NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|569008812|ref|XP_006527717|]
View 

polyglutamine-binding protein 1 isoform X1 [Mus musculus]

Protein Classification

WW domain-containing protein( domain architecture ID 10648633)

WW domain-containing protein; the WW domain mediates protein-protein interaction via proline-rich motifs, such as PPxY; similar to mammalian polyglutamine-binding protein 1, an intrinsically disordered protein that acts as a scaffold and is involved in different processes, such as pre-mRNA splicing, transcription regulation, innate immunity and neuron development

CATH:  2.20.70.10
Gene Ontology:  GO:0005515
PubMed:  22201747|9029943
SCOP:  3001621

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
WW smart00456
Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ...
47-78 2.46e-04

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides.


:

Pssm-ID: 197736 [Multi-domain]  Cd Length: 33  Bit Score: 37.58  E-value: 2.46e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 569008812    47 GLPPSWYKVFDPScGLPYYWNVETDLVSWLSP 78
Cdd:smart00456   1 PLPPGWEERKDPD-GRPYYYNHETKETQWEKP 31
 
Name Accession Description Interval E-value
WW smart00456
Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ...
47-78 2.46e-04

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides.


Pssm-ID: 197736 [Multi-domain]  Cd Length: 33  Bit Score: 37.58  E-value: 2.46e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 569008812    47 GLPPSWYKVFDPScGLPYYWNVETDLVSWLSP 78
Cdd:smart00456   1 PLPPGWEERKDPD-GRPYYYNHETKETQWEKP 31
 
Name Accession Description Interval E-value
WW smart00456
Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ...
47-78 2.46e-04

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides.


Pssm-ID: 197736 [Multi-domain]  Cd Length: 33  Bit Score: 37.58  E-value: 2.46e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 569008812    47 GLPPSWYKVFDPScGLPYYWNVETDLVSWLSP 78
Cdd:smart00456   1 PLPPGWEERKDPD-GRPYYYNHETKETQWEKP 31
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH