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Conserved domains on  [gi|568984296|ref|XP_006517630|]
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homeobox protein orthopedia isoform X1 [Mus musculus]

Protein Classification

homeobox domain-containing protein( domain architecture ID 11079034)

homeobox domain-containing protein may be involved in the transcriptional regulation of key eukaryotic developmental processes; also contains an OAR domain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
93-143 5.67e-23

Homeodomain;


:

Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 89.48  E-value: 5.67e-23
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568984296   93 RHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRR 143
Cdd:pfam00046   2 RKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRR 52
OAR pfam03826
OAR motif; The entry represents the OAR motif.
 290-307 4.71e-05

OAR motif; The entry represents the OAR motif.


:

Pssm-ID: 461067  Cd Length: 19  Bit Score: 39.70  E-value: 4.71e-05
                          10
                  ....*....|....*...
gi 568984296  290 WRGTSIASLRRKALEHTV 307
Cdd:pfam03826   2 RRSSSIASLRLKAKEHSA 19
 
Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
93-143 5.67e-23

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 89.48  E-value: 5.67e-23
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568984296   93 RHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRR 143
Cdd:pfam00046   2 RKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRR 52
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 93-142 1.17e-20

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 83.45  E-value: 1.17e-20
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 568984296    93 RHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNR 142
Cdd:smart00389   3 RKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNR 52
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 93-143 3.79e-20

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 82.29  E-value: 3.79e-20
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 568984296  93 RHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRR 143
Cdd:cd00086    2 RKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRR 52
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
93-141 1.09e-11

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 62.07  E-value: 1.09e-11
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 568984296  93 RHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQN 141
Cdd:COG5576   53 SKRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQN 101
OAR pfam03826
OAR motif; The entry represents the OAR motif.
 290-307 4.71e-05

OAR motif; The entry represents the OAR motif.


Pssm-ID: 461067  Cd Length: 19  Bit Score: 39.70  E-value: 4.71e-05
                          10
                  ....*....|....*...
gi 568984296  290 WRGTSIASLRRKALEHTV 307
Cdd:pfam03826   2 RRSSSIASLRLKAKEHSA 19
 
Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
93-143 5.67e-23

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 89.48  E-value: 5.67e-23
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568984296   93 RHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRR 143
Cdd:pfam00046   2 RKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRR 52
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 93-142 1.17e-20

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 83.45  E-value: 1.17e-20
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 568984296    93 RHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNR 142
Cdd:smart00389   3 RKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNR 52
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 93-143 3.79e-20

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 82.29  E-value: 3.79e-20
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 568984296  93 RHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRR 143
Cdd:cd00086    2 RKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRR 52
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
93-141 1.09e-11

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 62.07  E-value: 1.09e-11
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 568984296  93 RHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQN 141
Cdd:COG5576   53 SKRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQN 101
OAR pfam03826
OAR motif; The entry represents the OAR motif.
 290-307 4.71e-05

OAR motif; The entry represents the OAR motif.


Pssm-ID: 461067  Cd Length: 19  Bit Score: 39.70  E-value: 4.71e-05
                          10
                  ....*....|....*...
gi 568984296  290 WRGTSIASLRRKALEHTV 307
Cdd:pfam03826   2 RRSSSIASLRLKAKEHSA 19
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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