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Conserved domains on  [gi|568978510|ref|XP_006515389|]
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tetratricopeptide repeat protein 7B isoform X3 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TTC7_N pfam19440
Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a ...
 1-386 0e+00

Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a protein that forms the regulatory subunit of the PI4KIIIalpha complex (also known as PI4KA). This complex is composed of PI4KIIIalpha, TTC7 and FAM126A and catalyzes the first step in plasma membrane phosphoinositide synthesis. This TTC7 N-terminal domain contains basic residues suitable for interaction with the acidic inner leaflet of the plasma membrane and is required for localising the active site near its substrate. TTC7 acts as a bridge between PI4KA and EFR3B-FAM126A, via direct interactions. ERF3B is not part of the complex but contributes to its recruitment to the membrane.


:

Pssm-ID: 466084  Cd Length: 386  Bit Score: 697.30  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510    1 MATRKAGSRLETEIERCRSECQWERIPELVKQLSAKLIANDDMAELLLGESKLEQHLKEKPLRQGASPRGPRPQLTEVRK 80
Cdd:pfam19440   3 SRISFSGYRLETEIERCRSECQWDKVPELVEQLKAKRIANDDMANLLLGEGKLEQYLKENPPILENSTEKNQPKLSEAKK 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510   81 HLTAALDRGNLKSEFLQESNLVMAKLTYVEGDYKEALNIYARVGLDDLPLTAVPPYRLRMIAEAYATKGLCLEKLPVSSS 160
Cdd:pfam19440  83 HLTSALDRGNLKPEFLQEAHLLLAKLNYVEGDYREALNMYARAGLDDLTLKELPVYRLRLLAEAYAIKGLCLEKQAVSSS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  161 TSNLHVDREQDVITCYEKAGDIALLYLQEIERVMlTNIQNRSPKPGPAPHDQELGFFLETGLQRAHVLYFKNGNLTRGVG 240
Cdd:pfam19440 163 SRVRLAEREEEMITCYEKAGDIALLYLQELERIN-SNTQNRSPKPGPPSQEQELGFFLETALQRAYVLYFKKGNLARGVG 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  241 RFRELLRAVETRTTQNLRMTIARQLAEILLRGMCEQSYWSPLEEPPYQSPLDDPLrKGANTKAYTLPRRARVYSGENIFC 320
Cdd:pfam19440 242 RYREILRAVETRTTQNLRMTIARQLAEVLLRGVCEQSYWNPLEDPPPQSLLDEPL-KGTNTKNYTPSRKPRVYSGENIFC 320

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568978510  321 PQENTEEALLLLLISESMANRDAVLSRIPEHKSDRLISLQSASVVYDLLTIALGRRGQYEMLSECL 386
Cdd:pfam19440 321 PQDNVEEALLLLLISESMANRDAVLSRSPEHREARIISLQNATAVYDLLTIAMGRRGQYEMLSECL 386
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
781-914 7.07e-22

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 95.84  E-value: 7.07e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 781 LAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVL 860
Cdd:COG0457    7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLAL 86

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 568978510 861 HQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELE 914
Cdd:COG0457   87 QALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELD 140
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 371-611 5.28e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.45  E-value: 5.28e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 371 IALG----RRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCVGSLH 446
Cdd:COG2956   46 LALGnlyrRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGD 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 447 WlEEAEKFAKTVVDVGEKTSEFkakgYLALGLTYslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLA 526
Cdd:COG2956  126 W-EKAIEVLERLLKLGPENAHA----YCELAELY-----------LEQGDYDEAIEALEKALKLDPDCARALLLLAELYL 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 527 ISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENfILLFSKVKLESLCRGPDEALLTC 606
Cdd:COG2956  190 EQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD-DLLLALADLLERKEGLEAALALL 268


                 ....*
gi 568978510 607 KHMLQ 611
Cdd:COG2956  269 ERQLR 273
 
Name Accession Description Interval E-value
TTC7_N pfam19440
Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a ...
 1-386 0e+00

Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a protein that forms the regulatory subunit of the PI4KIIIalpha complex (also known as PI4KA). This complex is composed of PI4KIIIalpha, TTC7 and FAM126A and catalyzes the first step in plasma membrane phosphoinositide synthesis. This TTC7 N-terminal domain contains basic residues suitable for interaction with the acidic inner leaflet of the plasma membrane and is required for localising the active site near its substrate. TTC7 acts as a bridge between PI4KA and EFR3B-FAM126A, via direct interactions. ERF3B is not part of the complex but contributes to its recruitment to the membrane.


Pssm-ID: 466084  Cd Length: 386  Bit Score: 697.30  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510    1 MATRKAGSRLETEIERCRSECQWERIPELVKQLSAKLIANDDMAELLLGESKLEQHLKEKPLRQGASPRGPRPQLTEVRK 80
Cdd:pfam19440   3 SRISFSGYRLETEIERCRSECQWDKVPELVEQLKAKRIANDDMANLLLGEGKLEQYLKENPPILENSTEKNQPKLSEAKK 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510   81 HLTAALDRGNLKSEFLQESNLVMAKLTYVEGDYKEALNIYARVGLDDLPLTAVPPYRLRMIAEAYATKGLCLEKLPVSSS 160
Cdd:pfam19440  83 HLTSALDRGNLKPEFLQEAHLLLAKLNYVEGDYREALNMYARAGLDDLTLKELPVYRLRLLAEAYAIKGLCLEKQAVSSS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  161 TSNLHVDREQDVITCYEKAGDIALLYLQEIERVMlTNIQNRSPKPGPAPHDQELGFFLETGLQRAHVLYFKNGNLTRGVG 240
Cdd:pfam19440 163 SRVRLAEREEEMITCYEKAGDIALLYLQELERIN-SNTQNRSPKPGPPSQEQELGFFLETALQRAYVLYFKKGNLARGVG 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  241 RFRELLRAVETRTTQNLRMTIARQLAEILLRGMCEQSYWSPLEEPPYQSPLDDPLrKGANTKAYTLPRRARVYSGENIFC 320
Cdd:pfam19440 242 RYREILRAVETRTTQNLRMTIARQLAEVLLRGVCEQSYWNPLEDPPPQSLLDEPL-KGTNTKNYTPSRKPRVYSGENIFC 320

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568978510  321 PQENTEEALLLLLISESMANRDAVLSRIPEHKSDRLISLQSASVVYDLLTIALGRRGQYEMLSECL 386
Cdd:pfam19440 321 PQDNVEEALLLLLISESMANRDAVLSRSPEHREARIISLQNATAVYDLLTIAMGRRGQYEMLSECL 386
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
781-914 7.07e-22

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 95.84  E-value: 7.07e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 781 LAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVL 860
Cdd:COG0457    7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLAL 86

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 568978510 861 HQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELE 914
Cdd:COG0457   87 QALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELD 140
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 371-611 5.28e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.45  E-value: 5.28e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 371 IALG----RRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCVGSLH 446
Cdd:COG2956   46 LALGnlyrRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGD 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 447 WlEEAEKFAKTVVDVGEKTSEFkakgYLALGLTYslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLA 526
Cdd:COG2956  126 W-EKAIEVLERLLKLGPENAHA----YCELAELY-----------LEQGDYDEAIEALEKALKLDPDCARALLLLAELYL 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 527 ISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENfILLFSKVKLESLCRGPDEALLTC 606
Cdd:COG2956  190 EQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD-DLLLALADLLERKEGLEAALALL 268


                 ....*
gi 568978510 607 KHMLQ 611
Cdd:COG2956  269 ERQLR 273
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 755-928 3.89e-10

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 63.46  E-value: 3.89e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  755 EQALSEVASSLQssapkqgpLHPWMTlaQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDE 834
Cdd:TIGR00990 348 LEALADLSKSIE--------LDPRVT--QSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQ 417

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  835 ARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELE 914
Cdd:TIGR00990 418 AGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELE 497

                         170
                  ....*....|....
gi 568978510  915 ASSPAVPFTVIPRV 928
Cdd:TIGR00990 498 KETKPMYMNVLPLI 511
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 326-433 8.88e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.80  E-value: 8.88e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 326 EEALLLLLISESMANRDAVLSRIPEHKSDRLISLQSASVVYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFAL 405
Cdd:COG5010   17 LTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLAL 96

                         90       100
                 ....*....|....*....|....*...
gi 568978510 406 SLMAAGKSARAVKVLKECIRLKPDDATI 433
Cdd:COG5010   97 LYSRSGDKDEAKEYYEKALALSPDNPNA 124
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 818-848 1.54e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 39.81  E-value: 1.54e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 568978510  818 VLYMRGQVAELRGHFDEARRWYEEALSISPT 848
Cdd:pfam07719   3 ALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 755-903 8.76e-04

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 42.87  E-value: 8.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 755 EQALsEVASSLQSSapKQGPLHPwmTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDE 834
Cdd:PRK11788 158 QKAI-DVAERLEKL--GGDSLRV--EIAHFYCELAQQALARGDLDAARALLKKALAADPQCVRASILLGDLALAQGDYAA 232

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 835 ARRWYEEALSISPTHV-KSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAhEVWNGLGEVLQAQGNDAAA 903
Cdd:PRK11788 233 AIEALERVEEQDPEYLsEVLPKLMECYQALGDEAEGLEFLRRALEEYPGA-DLLLALAQLLEEQEGPEAA 301
pgaA PRK10049
outer membrane protein PgaA; Provisional
 482-603 1.80e-03

outer membrane protein PgaA; Provisional


Pssm-ID: 236644 [Multi-domain]  Cd Length: 765  Bit Score: 42.01  E-value: 1.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 482 LQATDASLRGMQEglQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSA 561
Cdd:PRK10049  52 YAAVAVAYRNLKQ--WQNSLTLWQKALSLEPQNDDYQRGLILTLADAGQYDEALVKAKQLVSGAPDKANLLALAYVYKRA 129

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 568978510 562 QKHYhDALNIIDMALSEYPENFILLFSKVKLESLCRGPDEAL 603
Cdd:PRK10049 130 GRHW-DELRAMTQALPRAPQTQQYPTEYVQALRNNRLSAPAL 170
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 401-582 6.37e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.45  E-value: 6.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  401 YQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCVGSlhwleeaEKFaKTVVDVGEKTSEFKAKGYLALgltY 480
Cdd:TIGR02917  60 FLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQ-------GKF-QQVLDELPGKTLLDDEGAAEL---L 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  481 SLQATDASLRGMQEglqrKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLS 560
Cdd:TIGR02917 129 ALRGLAYLGLGQLE----LAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLL 204

                         170       180
                  ....*....|....*....|..
gi 568978510  561 AQKHYHDALNIIDMALSEYPEN 582
Cdd:TIGR02917 205 SLGNIELALAAYRKAIALRPNN 226
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 829-913 7.34e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.53  E-value: 7.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 829 RGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTA-HEVWNGLGEVLqaQGNDAAatECF 907
Cdd:cd24142   13 QGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGgYEKYLYLGQLS--GGEEAL--QYY 88


                 ....*.
gi 568978510 908 LTALEL 913
Cdd:cd24142   89 EKGIEI 94
 
Name Accession Description Interval E-value
TTC7_N pfam19440
Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a ...
 1-386 0e+00

Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a protein that forms the regulatory subunit of the PI4KIIIalpha complex (also known as PI4KA). This complex is composed of PI4KIIIalpha, TTC7 and FAM126A and catalyzes the first step in plasma membrane phosphoinositide synthesis. This TTC7 N-terminal domain contains basic residues suitable for interaction with the acidic inner leaflet of the plasma membrane and is required for localising the active site near its substrate. TTC7 acts as a bridge between PI4KA and EFR3B-FAM126A, via direct interactions. ERF3B is not part of the complex but contributes to its recruitment to the membrane.


Pssm-ID: 466084  Cd Length: 386  Bit Score: 697.30  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510    1 MATRKAGSRLETEIERCRSECQWERIPELVKQLSAKLIANDDMAELLLGESKLEQHLKEKPLRQGASPRGPRPQLTEVRK 80
Cdd:pfam19440   3 SRISFSGYRLETEIERCRSECQWDKVPELVEQLKAKRIANDDMANLLLGEGKLEQYLKENPPILENSTEKNQPKLSEAKK 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510   81 HLTAALDRGNLKSEFLQESNLVMAKLTYVEGDYKEALNIYARVGLDDLPLTAVPPYRLRMIAEAYATKGLCLEKLPVSSS 160
Cdd:pfam19440  83 HLTSALDRGNLKPEFLQEAHLLLAKLNYVEGDYREALNMYARAGLDDLTLKELPVYRLRLLAEAYAIKGLCLEKQAVSSS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  161 TSNLHVDREQDVITCYEKAGDIALLYLQEIERVMlTNIQNRSPKPGPAPHDQELGFFLETGLQRAHVLYFKNGNLTRGVG 240
Cdd:pfam19440 163 SRVRLAEREEEMITCYEKAGDIALLYLQELERIN-SNTQNRSPKPGPPSQEQELGFFLETALQRAYVLYFKKGNLARGVG 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  241 RFRELLRAVETRTTQNLRMTIARQLAEILLRGMCEQSYWSPLEEPPYQSPLDDPLrKGANTKAYTLPRRARVYSGENIFC 320
Cdd:pfam19440 242 RYREILRAVETRTTQNLRMTIARQLAEVLLRGVCEQSYWNPLEDPPPQSLLDEPL-KGTNTKNYTPSRKPRVYSGENIFC 320

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568978510  321 PQENTEEALLLLLISESMANRDAVLSRIPEHKSDRLISLQSASVVYDLLTIALGRRGQYEMLSECL 386
Cdd:pfam19440 321 PQDNVEEALLLLLISESMANRDAVLSRSPEHREARIISLQNATAVYDLLTIAMGRRGQYEMLSECL 386
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
781-914 7.07e-22

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 95.84  E-value: 7.07e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 781 LAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVL 860
Cdd:COG0457    7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLAL 86

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 568978510 861 HQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELE 914
Cdd:COG0457   87 QALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELD 140
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 779-920 8.83e-20

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 94.67  E-value: 8.83e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 779 MTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLAL 858
Cdd:COG3914   75 LLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGE 154

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568978510 859 VLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEASSPAV 920
Cdd:COG3914  155 ALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 782-915 1.22e-17

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 80.24  E-value: 1.22e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 782 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLH 861
Cdd:COG4783    4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 568978510 862 QLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEA 915
Cdd:COG4783   84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
782-915 5.02e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 81.59  E-value: 5.02e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 782 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLH 861
Cdd:COG0457   42 AEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALL 121

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 568978510 862 QLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEA 915
Cdd:COG0457  122 ELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAAL 175
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
811-920 2.23e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 79.67  E-value: 2.23e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 811 LFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGL 890
Cdd:COG0457    3 LDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82

                         90       100       110
                 ....*....|....*....|....*....|
gi 568978510 891 GEVLQAQGNDAAATECFLTALELEASSPAV 920
Cdd:COG0457   83 GLALQALGRYEEALEDYDKALELDPDDAEA 112
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 782-920 5.45e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 76.31  E-value: 5.45e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 782 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLH 861
Cdd:COG2956  110 AEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYL 189

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 568978510 862 QLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEASSPAV 920
Cdd:COG2956  190 EQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLL 248
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 746-920 2.24e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 77.34  E-value: 2.24e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 746 ATSVAASRVEQALSEVASSLQSSAPKQGPLHPWMTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQV 825
Cdd:COG3914    8 ALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 826 AELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATE 905
Cdd:COG3914   88 LQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIA 167

                        170
                 ....*....|....*
gi 568978510 906 CFLTALELEASSPAV 920
Cdd:COG3914  168 ALRRALELDPDNAEA 182
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 818-920 3.07e-14

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 70.61  E-value: 3.07e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 818 VLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQ 897
Cdd:COG4783    6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                         90       100
                 ....*....|....*....|...
gi 568978510 898 GNDAAATECFLTALELEASSPAV 920
Cdd:COG4783   86 GDYDEALALLEKALKLDPEHPEA 108
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 755-912 3.52e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 74.00  E-value: 3.52e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 755 EQALsEVASSLQSSAPKQgplhpwmtlAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDE 834
Cdd:COG2956  127 EKAI-EVLERLLKLGPEN---------AHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEE 196

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568978510 835 ARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAhEVWNGLGEVLQAQGNDAAATECFLTALE 912
Cdd:COG2956  197 AIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD-DLLLALADLLERKEGLEAALALLERQLR 273
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 782-920 1.38e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 72.07  E-value: 1.38e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 782 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLH 861
Cdd:COG2956   76 AEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYL 155

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 568978510 862 QLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEASSPAV 920
Cdd:COG2956  156 EQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPA 214
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 785-913 2.74e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 71.30  E-value: 2.74e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 785 WLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLG 864
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 568978510 865 RYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALEL 913
Cdd:COG2956   91 LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKL 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 782-920 5.88e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 70.14  E-value: 5.88e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 782 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLH 861
Cdd:COG2956   42 VEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYE 121

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 568978510 862 QLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEASSPAV 920
Cdd:COG2956  122 QEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARA 180
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 782-880 1.42e-12

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 65.41  E-value: 1.42e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 782 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLH 861
Cdd:COG4235   17 AEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAF 96

                         90
                 ....*....|....*....
gi 568978510 862 QLGRYSLAEKILRDAVQVN 880
Cdd:COG4235   97 QQGDYAEAIAAWQKLLALL 115
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 735-880 2.61e-12

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 65.75  E-value: 2.61e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 735 HAGMEEAGSVHATSVAASRVEQALSEVASSLQSSAPKQGPLHPWMTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPM 814
Cdd:COG5010    7 FDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPN 86

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568978510 815 SHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVN 880
Cdd:COG5010   87 NPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 782-924 4.83e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 69.64  E-value: 4.83e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 782 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLH 861
Cdd:COG3914  112 AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQ 191

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568978510 862 QLGRYSLAEKILRDAVQVNSTAHEVW-NGLGEVLQAQGNDAAATECFLTALELEASSPAVPFTV 924
Cdd:COG3914  192 DLGRLEEAIAAYRRALELDPDNADAHsNLLFALRQACDWEVYDRFEELLAALARGPSELSPFAL 255
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
825-916 5.13e-12

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 62.88  E-value: 5.13e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 825 VAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKiLRDAVQVNSTAHEVWNGLGEVLQAQGNDAAAT 904
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|..
gi 568978510 905 ECFLTALELEAS 916
Cdd:COG3063   80 AYLERALELDPS 91
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 371-611 5.28e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.45  E-value: 5.28e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 371 IALG----RRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCVGSLH 446
Cdd:COG2956   46 LALGnlyrRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGD 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 447 WlEEAEKFAKTVVDVGEKTSEFkakgYLALGLTYslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLA 526
Cdd:COG2956  126 W-EKAIEVLERLLKLGPENAHA----YCELAELY-----------LEQGDYDEAIEALEKALKLDPDCARALLLLAELYL 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 527 ISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENfILLFSKVKLESLCRGPDEALLTC 606
Cdd:COG2956  190 EQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD-DLLLALADLLERKEGLEAALALL 268


                 ....*
gi 568978510 607 KHMLQ 611
Cdd:COG2956  269 ERQLR 273
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 800-913 1.12e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 63.10  E-value: 1.12e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 800 EATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQV 879
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 568978510 880 NSTAHEVWNGLGEVLQAQGNDAAATECFLTALEL 913
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLAL 114
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 825-914 2.50e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 62.67  E-value: 2.50e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 825 VAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAAT 904
Cdd:COG5010   63 LYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAK 142

                         90
                 ....*....|
gi 568978510 905 ECFLTALELE 914
Cdd:COG5010  143 AALQRALGTS 152
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
791-885 2.77e-11

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 60.57  E-value: 2.77e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 791 VYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRwYEEALSISPTHVKSMQRLALVLHQLGRYSLAE 870
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|....*
gi 568978510 871 KILRDAVQVNSTAHE 885
Cdd:COG3063   80 AYLERALELDPSALR 94
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 400-612 3.98e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 64.75  E-value: 3.98e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 400 WYQFALSLMAAGKSARAVKVLKECIRLKPDDAtipllAAKLCVGSLHW----LEEAEKFAKTVVDVGEKtsefKAKGYLA 475
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETV-----EAHLALGNLYRrrgeYDRAIRIHQKLLERDPD----RAEALLE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 476 LGLTYslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLL 555
Cdd:COG2956   82 LAQDY-----------LKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCEL 150

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 568978510 556 ALLLSAQKHYHDALNIIDMALSEYPENFILLFSKVKLESLCRGPDEALLTCKHMLQI 612
Cdd:COG2956  151 AELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQ 207
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
767-912 6.95e-11

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 63.01  E-value: 6.95e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 767 SSAPKQGPLHPWMTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSIS 846
Cdd:COG4785   58 LAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELD 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 847 PTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHE--VWNGL------------------GEVLQAQGNDAAATEC 906
Cdd:COG4785  138 PDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPEraLWLYLaerkldpekalallledwATAYLLQGDTEEAREL 217


                 ....*.
gi 568978510 907 FLTALE 912
Cdd:COG4785  218 FKLALA 223
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 755-928 3.89e-10

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 63.46  E-value: 3.89e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  755 EQALSEVASSLQssapkqgpLHPWMTlaQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDE 834
Cdd:TIGR00990 348 LEALADLSKSIE--------LDPRVT--QSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQ 417

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  835 ARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELE 914
Cdd:TIGR00990 418 AGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELE 497

                         170
                  ....*....|....
gi 568978510  915 ASSPAVPFTVIPRV 928
Cdd:TIGR00990 498 KETKPMYMNVLPLI 511
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
365-586 1.05e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 60.02  E-value: 1.05e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 365 VYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIpLLAAKLCVGS 444
Cdd:COG0457   10 AYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEA-LNNLGLALQA 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 445 LHWLEEAEKFAKTVVDVGEKtsefKAKGYLALGLTYslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQ 524
Cdd:COG0457   89 LGRYEEALEDYDKALELDPD----DAEALYNLGLAL-----------LELGRYDEAIEAYERALELDPDDADALYNLGIA 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568978510 525 LAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENFILL 586
Cdd:COG0457  154 LEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILT 215
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 782-922 1.25e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 62.41  E-value: 1.25e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  782 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLY-MRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVL 860
Cdd:TIGR02917  90 NQVLPLLARAYLLQGKFQQVLDELPGKTLLDDEGAAELLaLRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLA 169

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568978510  861 HQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEASSPAVPF 922
Cdd:TIGR02917 170 LAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLL 231
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 820-920 7.44e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.82  E-value: 7.44e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 820 YMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGN 899
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                         90       100
                 ....*....|....*....|.
gi 568978510 900 DAAATECFLTALELEASSPAV 920
Cdd:COG2956   92 LDRAEELLEKLLELDPDDAEA 112
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 492-612 4.14e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.93  E-value: 4.14e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 492 MQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNI 571
Cdd:COG3914   89 QALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAA 168

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 568978510 572 IDMALSEYPENFILLFSKVK-LESLCRgPDEALLTCKHMLQI 612
Cdd:COG3914  169 LRRALELDPDNAEALNNLGNaLQDLGR-LEEAIAAYRRALEL 209
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 470-582 4.80e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 52.70  E-value: 4.80e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 470 AKGYLALGLTYslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDA 549
Cdd:COG4235   17 AEGWLLLGRAY-----------LRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                         90       100       110
                 ....*....|....*....|....*....|...
gi 568978510 550 NSLHLLALLLSAQKHYHDALNIIDMALSEYPEN 582
Cdd:COG4235   86 EALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
843-920 8.09e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 54.24  E-value: 8.09e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568978510 843 LSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEASSPAV 920
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEA 78
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 781-888 1.28e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 55.38  E-value: 1.28e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 781 LAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVL 860
Cdd:COG3914  145 FAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFAL 224

                         90       100
                 ....*....|....*....|....*...
gi 568978510 861 HQLGRYSLAEKILRDAVQVNSTAHEVWN 888
Cdd:COG3914  225 RQACDWEVYDRFEELLAALARGPSELSP 252
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 359-549 3.52e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 54.23  E-value: 3.52e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 359 LQSASVVYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIpllaa 438
Cdd:COG3914   74 LLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEA----- 148

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 439 klcvgslhwleeaekfaktvvdvgektsefkakgYLALGLTYslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHQAA 518
Cdd:COG3914  149 ----------------------------------YLNLGEAL-----------RRLGRLEEAIAALRRALELDPDNAEAL 183

                        170       180       190
                 ....*....|....*....|....*....|.
gi 568978510 519 FYLALQLAISRQIPEALGYVRQALQLQGDDA 549
Cdd:COG3914  184 NNLGNALQDLGRLEEAIAAYRRALELDPDNA 214
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 782-919 6.12e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 53.55  E-value: 6.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  782 AQIWLHAAEVYIGIGKPAEATACTQEAANL----FPMSHNVLymrgQVAELRGHFDEARRWYEEALSISPTHVKSMQRLA 857
Cdd:TIGR02917 465 ASLHNLLGAIYLGKGDLAKAREAFEKALSIepdfFPAAANLA----RIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALA 540

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568978510  858 LVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEASSPA 919
Cdd:TIGR02917 541 GLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPE 602
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 400-548 1.22e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 48.65  E-value: 1.22e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 400 WYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCVGSLHWlEEAEKFAKTVVDVGEKTSEFkakgYLALGLT 479
Cdd:COG4783    7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDL-DEAIVLLHEALELDPDEPEA----RLNLGLA 81

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568978510 480 YslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDD 548
Cdd:COG4783   82 L-----------LKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 796-878 1.44e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 47.68  E-value: 1.44e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 796 GKPAEATACTQEAANLFPMSH---NVLYMRGQVAELRGHFDEARRWYEEALSISPTHVK---SMQRLALVLHQLGRYSLA 869
Cdd:COG1729    7 GDYDEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELGDYDKA 86


                 ....*....
gi 568978510 870 EKILRDAVQ 878
Cdd:COG1729   87 RATLEELIK 95
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 261-535 1.86e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 51.92  E-value: 1.86e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 261 IARQLAEILLRGMCEQSYWSPLEEPPYQSPLDDPLRKGANTKAYTLPRRARVYSGENIFCPQENTEEALLLLLISESMAN 340
Cdd:COG3914   21 AAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALAL 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 341 RDAVLSRIPEHksdrlislqsaSVVYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVL 420
Cdd:COG3914  101 YRRALALNPDN-----------AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAAL 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 421 KECIRLKPDDATIPLLAAKLCvGSLHWLEEAEKFAKTVVDVgeKTSEFKAKGYLALGLTYS-----LQATDASLRGMQEG 495
Cdd:COG3914  170 RRALELDPDNAEALNNLGNAL-QDLGRLEEAIAAYRRALEL--DPDNADAHSNLLFALRQAcdwevYDRFEELLAALARG 246

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 568978510 496 LQRKALLAFQRAHSLSPTDHqaafyLALQLAISRQIPEAL 535
Cdd:COG3914  247 PSELSPFALLYLPDDDPAEL-----LALARAWAQLVAAAA 281
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 782-847 2.58e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 47.69  E-value: 2.58e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568978510 782 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISP 847
Cdd:COG4235   51 ADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLP 116
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 384-550 3.16e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 47.31  E-value: 3.16e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 384 ECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIpllaaklcvgslhwleeaekfaktvvdvge 463
Cdd:COG4235    4 ARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADA------------------------------ 53

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 464 ktsefkakgYLALGLTYslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQ 543
Cdd:COG4235   54 ---------LLDLAEAL-----------LAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLA 113


                 ....*..
gi 568978510 544 LQGDDAN 550
Cdd:COG4235  114 LLPADAP 120
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
400-603 4.90e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 48.85  E-value: 4.90e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 400 WYQFALSLMAAGKSARAVKVLKECIRLKPDDATIpllaaklcvgslhwleeaekfaktvvdvgektsefkakgYLALGLT 479
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEA---------------------------------------LYNLGLA 51

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 480 YslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLL 559
Cdd:COG0457   52 Y-----------LRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLAL 120

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 568978510 560 SAQKHYHDALNIIDMALSEYPENFILLFSKVKLESLCRGPDEAL 603
Cdd:COG0457  121 LELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEAL 164
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 756-920 1.52e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.93  E-value: 1.52e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  756 QALSeVASSLQSSAPKQgplhpwmtlAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEA 835
Cdd:TIGR02917 585 KALA-ILNEAADAAPDS---------PEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKA 654

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  836 RRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEA 915
Cdd:TIGR02917 655 ITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAP 734


                  ....*
gi 568978510  916 SSPAV 920
Cdd:TIGR02917 735 SSQNA 739
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 750-920 1.59e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.93  E-value: 1.59e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  750 AASRVEQALSEVASSLQssapkqgpLHPWMTLAQIWLhaAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELR 829
Cdd:TIGR02917 647 VMKNYAKAITSLKRALE--------LKPDNTEAQIGL--AQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQ 716

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  830 GHFDEARRWYEEALSISPTHVKSMQrLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLT 909
Cdd:TIGR02917 717 KDYPAAIQAYRKALKRAPSSQNAIK-LHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQT 795

                         170
                  ....*....|.
gi 568978510  910 ALELEASSPAV 920
Cdd:TIGR02917 796 VVKKAPDNAVV 806
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 354-440 1.83e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.57  E-value: 1.83e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 354 DRLISLQSASV-VYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDAT 432
Cdd:COG4783   28 EKALELDPDNPeAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPE 107


                 ....*...
gi 568978510 433 IPLLAAKL 440
Cdd:COG4783  108 AYLRLARA 115
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
819-918 2.33e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 46.45  E-value: 2.33e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 819 LYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQG 898
Cdd:COG4785   76 YYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLG 155

                         90       100
                 ....*....|....*....|
gi 568978510 899 NDAAATECFLTALELEASSP 918
Cdd:COG4785  156 RYELAIADLEKALELDPNDP 175
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
782-847 3.09e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 43.62  E-value: 3.09e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568978510 782 AQIWLHAAEVYIGIGKPAEATACtQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISP 847
Cdd:COG3063   26 ADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDP 90
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 492-612 3.12e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.80  E-value: 3.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 492 MQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNI 571
Cdd:COG4783   15 LLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALAL 94

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 568978510 572 IDMALSEYPENFILLFSKVKLESLCRGPDEALLTCKHMLQI 612
Cdd:COG4783   95 LEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 492-580 4.70e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.57  E-value: 4.70e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 492 MQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNI 571
Cdd:COG5010   65 NKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAA 144


                 ....*....
gi 568978510 572 IDMALSEYP 580
Cdd:COG5010  145 LQRALGTSP 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 834-920 6.87e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.18  E-value: 6.87e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 834 EARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALEL 913
Cdd:COG5010   38 KEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALAL 117


                 ....*..
gi 568978510 914 EASSPAV 920
Cdd:COG5010  118 SPDNPNA 124
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 735-920 8.14e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.62  E-value: 8.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  735 HAGMEEAGSVHATSVAASRVEQALsEVASSLQSSApkqgplhpwmtlaQIWLHAAEVYIGIGKPAEATACTQEAANLFPM 814
Cdd:TIGR02917 703 ALGFELEGDLYLRQKDYPAAIQAY-RKALKRAPSS-------------QNAIKLHRALLASGNTAEAVKTLEAWLKTHPN 768

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  815 SHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGR---YSLAEKilrdAVQVNSTAHEVWNGLG 891
Cdd:TIGR02917 769 DAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKDpraLEYAER----ALKLAPNIPAILDTLG 844

                         170       180
                  ....*....|....*....|....*....
gi 568978510  892 EVLQAQGNDAAATECFLTALELEASSPAV 920
Cdd:TIGR02917 845 WLLVEKGEADRALPLLRKAVNIAPEAAAI 873
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 326-433 8.88e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.80  E-value: 8.88e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 326 EEALLLLLISESMANRDAVLSRIPEHKSDRLISLQSASVVYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFAL 405
Cdd:COG5010   17 LTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLAL 96

                         90       100
                 ....*....|....*....|....*...
gi 568978510 406 SLMAAGKSARAVKVLKECIRLKPDDATI 433
Cdd:COG5010   97 LYSRSGDKDEAKEYYEKALALSPDNPNA 124
LcrH_SycD TIGR02552
type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in ...
 855-922 9.41e-05

type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in type III secretion operons. LcrH, from Yersinia is believed to have a regulatory function in the low-calcium response of the secretion system. The same protein is also known as SycD (SYC = Specific Yop Chaperone) for its chaperone role. In Pseudomonas, where the homolog is known as PcrH, the chaperone role has been demonstrated and the regulatory role appears to be absent. ScyD/LcrH contains three central tetratricopeptide-like repeats that are predicted to fold into an all-alpha-helical array.


Pssm-ID: 274197 [Multi-domain]  Cd Length: 135  Bit Score: 43.05  E-value: 9.41e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568978510  855 RLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEASSPAVPF 922
Cdd:TIGR02552  22 ALAYNLYQQGRYDEALKLFQLLAAYDPYNSRYWLGLAACCQMLKEYEEAIDAYALAAALDPDDPRPYF 89
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 368-586 1.04e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 46.14  E-value: 1.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 368 LLTIALGRRGQYEMLSECLERAMKFAFEEFH---------LWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAA 438
Cdd:COG3914    6 LLALAALAAAALLAAAAAAELALAAELEAAAlaaalglalLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 439 KLCVgSLHWLEEAEKFAKTVVDVGEKTsefkAKGYLALGLTYSLQatdaslrgmqeGLQRKALLAFQRAHSLSPTDHQAA 518
Cdd:COG3914   86 LLLQ-ALGRYEEALALYRRALALNPDN----AEALFNLGNLLLAL-----------GRLEEALAALRRALALNPDFAEAY 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568978510 519 FYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENFILL 586
Cdd:COG3914  150 LNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAH 217
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 818-848 1.54e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 39.81  E-value: 1.54e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 568978510  818 VLYMRGQVAELRGHFDEARRWYEEALSISPT 848
Cdd:pfam07719   3 ALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 369-514 5.22e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 41.33  E-value: 5.22e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 369 LTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCVgSLHWL 448
Cdd:COG4783   10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL-KAGDY 88

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568978510 449 EEAEKFAKTVVDVGEKTSEFkakgYLALGLTYslqatdaslrgMQEGLQRKALLAFQRAHSLSPTD 514
Cdd:COG4783   89 DEALALLEKALKLDPEHPEA----YLRLARAY-----------RALGRPDEAIAALEKALELDPDD 139
TPR_19 pfam14559
Tetratricopeptide repeat;
830-897 5.46e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 39.10  E-value: 5.46e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568978510  830 GHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNglgevLQAQ 897
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAA-----LLAK 64
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
492-581 5.84e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.77  E-value: 5.84e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 492 MQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYvRQALQLQGDDANSLHLLALLLSAQKHYHDALNI 571
Cdd:COG3063    3 LKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEALAY 81

                         90
                 ....*....|
gi 568978510 572 IDMALSEYPE 581
Cdd:COG3063   82 LERALELDPS 91
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 771-847 6.81e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 40.36  E-value: 6.81e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 771 KQGPLHPWMTLAQIWLhaAEVYIGIGKPAEATACTQEAANLFPMSHNV---LYMRGQVAELRGHFDEARRWYEEALSISP 847
Cdd:COG1729   21 KRYPNSPLAPDALYWL--GEAYYALGDYDEAAEAFEKLLKRYPDSPKApdaLLKLGLSYLELGDYDKARATLEELIKKYP 98
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 360-545 6.98e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.41  E-value: 6.98e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 360 QSASVVYDLLTIALgRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAK 439
Cdd:COG2956  108 DDAEALRLLAEIYE-QEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAE 186

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 440 LcvgsLHWLEEAEKFAKTVVDVGEKTSEFkAKGYLALGLTYslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHqAAF 519
Cdd:COG2956  187 L----YLEQGDYEEAIAALERALEQDPDY-LPALPRLAELY-----------EKLGDPEEALELLRKALELDPSDD-LLL 249

                        170       180
                 ....*....|....*....|....*.
gi 568978510 520 YLALQLAISRQIPEALGYVRQALQLQ 545
Cdd:COG2956  250 ALADLLERKEGLEAALALLERQLRRH 275
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 782-847 7.08e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.10  E-value: 7.08e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568978510 782 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISP 847
Cdd:COG5010   88 PELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 792-903 7.62e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.53  E-value: 7.62e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  792 YIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEK 871
Cdd:TIGR02917 135 YLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALA 214

                          90       100       110
                  ....*....|....*....|....*....|..
gi 568978510  872 ILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAA 903
Cdd:TIGR02917 215 AYRKAIALRPNNIAVLLALATILIEAGEFEEA 246
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 755-903 8.76e-04

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 42.87  E-value: 8.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 755 EQALsEVASSLQSSapKQGPLHPwmTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDE 834
Cdd:PRK11788 158 QKAI-DVAERLEKL--GGDSLRV--EIAHFYCELAQQALARGDLDAARALLKKALAADPQCVRASILLGDLALAQGDYAA 232

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 835 ARRWYEEALSISPTHV-KSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAhEVWNGLGEVLQAQGNDAAA 903
Cdd:PRK11788 233 AIEALERVEEQDPEYLsEVLPKLMECYQALGDEAEGLEFLRRALEEYPGA-DLLLALAQLLEEQEGPEAA 301
TPR_12 pfam13424
Tetratricopeptide repeat;
855-913 8.95e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.91  E-value: 8.95e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568978510  855 RLALVLHQLGRYSLAEKILRDAVQVNSTAH--------EVWNGLGEVLQAQGNDAAATECFLTALEL 913
Cdd:pfam13424   8 NLAAVLRRLGRYDEALELLEKALEIARRLLgpdhpltaTTLLNLGRLYLELGRYEEALELLERALAL 74
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 749-920 9.10e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.15  E-value: 9.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  749 VAASRVEQALSeVASSLQssapKQGPLHpwmtlAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMrGQVAEL 828
Cdd:TIGR02917 680 LAAKRTESAKK-IAKSLQ----KQHPKA-----ALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIKL-HRALLA 748

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  829 RGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQaQGNDAAATECFL 908
Cdd:TIGR02917 749 SGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYL-ELKDPRALEYAE 827

                         170
                  ....*....|..
gi 568978510  909 TALELEASSPAV 920
Cdd:TIGR02917 828 RALKLAPNIPAI 839
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 782-849 1.67e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.79  E-value: 1.67e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568978510 782 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTH 849
Cdd:COG4783   72 PEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
365-531 1.73e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.15  E-value: 1.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 365 VYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIpLLAAKLCVGS 444
Cdd:COG0457   78 ALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADA-LYNLGIALEK 156

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 445 LHWLEEAEKFAKTVVDVGEKTSEFKAKGYLALGLTYSLQATDASLRGMQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQ 524
Cdd:COG0457  157 LGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLA 236


                 ....*..
gi 568978510 525 LAISRQI 531
Cdd:COG0457  237 ALALYQY 243
pgaA PRK10049
outer membrane protein PgaA; Provisional
 482-603 1.80e-03

outer membrane protein PgaA; Provisional


Pssm-ID: 236644 [Multi-domain]  Cd Length: 765  Bit Score: 42.01  E-value: 1.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 482 LQATDASLRGMQEglQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSA 561
Cdd:PRK10049  52 YAAVAVAYRNLKQ--WQNSLTLWQKALSLEPQNDDYQRGLILTLADAGQYDEALVKAKQLVSGAPDKANLLALAYVYKRA 129

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 568978510 562 QKHYhDALNIIDMALSEYPENFILLFSKVKLESLCRGPDEAL 603
Cdd:PRK10049 130 GRHW-DELRAMTQALPRAPQTQQYPTEYVQALRNNRLSAPAL 170
TPR_12 pfam13424
Tetratricopeptide repeat;
781-845 2.46e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 37.75  E-value: 2.46e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568978510  781 LAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSH--------NVLYMRGQVAELRGHFDEARRWYEEALSI 845
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLLgpdhpltaTTLLNLGRLYLELGRYEEALELLERALAL 74
YfgM COG2976
Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal ...
 830-919 3.53e-03

Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal transduction mechanisms];


Pssm-ID: 442215 [Multi-domain]  Cd Length: 207  Bit Score: 39.84  E-value: 3.53e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 830 GHFDEARRWYEEALSISPTH-VKSM--QRLALVLHQLGRYSLAEKILrDAVQVNSTAHEVWNGLGEVLQAQGNDAAATEC 906
Cdd:COG2976  104 GDLDKAAAQLQWVLDNAKDPaLKALarLRLARVLLAQKKYDEALATL-DAVKPEAFAALYAELRGDILLAQGDKAEARAA 182

                         90
                 ....*....|...
gi 568978510 907 FLTALELEASSPA 919
Cdd:COG2976  183 YQKALAALPEDAP 195
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 499-587 3.96e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.45  E-value: 3.96e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 499 KALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSE 578
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80


                 ....*....
gi 568978510 579 YPENFILLF 587
Cdd:COG4235   81 DPDNPEALY 89
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 829-921 4.90e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.66  E-value: 4.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 829 RGHFDEARRWYEEALSISPTHVKSMQ---RLALVLHQLGRYSLAEKILRDAVQV---NSTAHEVWNGLGEVLQAQGNDAA 902
Cdd:COG1729    6 AGDYDEAIAAFKAFLKRYPNSPLAPDalyWLGEAYYALGDYDEAAEAFEKLLKRypdSPKAPDALLKLGLSYLELGDYDK 85

                         90
                 ....*....|....*....
gi 568978510 903 ATECFLTALELEASSPAVP 921
Cdd:COG1729   86 ARATLEELIKKYPDSEAAK 104
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
782-903 5.03e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 39.60  E-value: 5.03e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 782 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLH 861
Cdd:COG0457  110 AEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALA 189

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 568978510 862 QLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAA 903
Cdd:COG0457  190 LAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLL 231
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 366-438 5.23e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.06  E-value: 5.23e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568978510 366 YDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAA 438
Cdd:COG4235   20 WLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLG 92
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 401-582 6.37e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.45  E-value: 6.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  401 YQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCVGSlhwleeaEKFaKTVVDVGEKTSEFKAKGYLALgltY 480
Cdd:TIGR02917  60 FLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQ-------GKF-QQVLDELPGKTLLDDEGAAEL---L 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  481 SLQATDASLRGMQEglqrKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLS 560
Cdd:TIGR02917 129 ALRGLAYLGLGQLE----LAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLL 204

                         170       180
                  ....*....|....*....|..
gi 568978510  561 AQKHYHDALNIIDMALSEYPEN 582
Cdd:TIGR02917 205 SLGNIELALAAYRKAIALRPNN 226
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 829-913 7.34e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.53  E-value: 7.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 829 RGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTA-HEVWNGLGEVLqaQGNDAAatECF 907
Cdd:cd24142   13 QGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGgYEKYLYLGQLS--GGEEAL--QYY 88


                 ....*.
gi 568978510 908 LTALEL 913
Cdd:cd24142   89 EKGIEI 94
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 820-883 7.69e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 35.77  E-value: 7.69e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568978510  820 YMRGQVAELRGHFDEARRWYEEAL---SISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTA 883
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALarfPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
789-919 7.86e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 39.09  E-value: 7.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 789 AEVYIGIGKPAEATACTQEAAN-LFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRL--ALVLHQLGR 865
Cdd:COG4700   96 ADALLELGRYDEAIELYEEALTgIFADDPHILLGLAQALFELGRYAEALETLEKLIAKNPDFKSSDAHLlyARALEALGD 175

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 568978510 866 YSLAEKILRDAVQVNSTAhEVWNGLGEVLQAQGNDAAATECFLTALELEASSPA 919
Cdd:COG4700  176 LEAAEAELEALARRYSGP-EARYRYAKFLARQGRTAEAKELLEEILDEAKHMPK 228
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 787-878 8.36e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 8.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510  787 HAAEVYIGI--GKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLG 864
Cdd:TIGR02917 230 LLALATILIeaGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLG 309

                          90
                  ....*....|....
gi 568978510  865 RYSLAEKILRDAVQ 878
Cdd:TIGR02917 310 NLEQAYQYLNQILK 323
PRK12370 PRK12370
HilA/EilA family virulence transcriptional regulator;
415-545 9.37e-03

HilA/EilA family virulence transcriptional regulator;


Pssm-ID: 237080 [Multi-domain]  Cd Length: 553  Bit Score: 39.84  E-value: 9.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978510 415 RAVKVLKECIRLKPDDaTIPLLAAKLCVGSLHWL--EEAEKFAKTVVDVGEKTSEFKAKGYLALGLTyslqATDASLRGM 492
Cdd:PRK12370 279 QALKLLTQCVNMSPNS-IAPYCALAECYLSMAQMgiFDKQNAMIKAKEHAIKATELDHNNPQALGLL----GLINTIHSE 353

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 568978510 493 QEglqrKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQ 545
Cdd:PRK12370 354 YI----VGSLLFKQANLLSPISADIKYYYGWNLFMAGQLEEALQTINECLKLD 402
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 856-922 9.47e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.15  E-value: 9.47e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568978510 856 LALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEASSPAVPF 922
Cdd:cd24142    6 KAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYEKY 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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