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Conserved domains on  [gi|568967308|ref|XP_006513590|]
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centrosomal protein of 290 kDa isoform X2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CEP209_CC5 pfam16574
Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry ...
 1314-1441 5.64e-36

Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry a number of coiled-coil regions, and this is the fifth along the length of the protein. It is thought that the proteins are involved in cilia biosynthesis.


:

Pssm-ID: 465184 [Multi-domain]  Cd Length: 128  Bit Score: 133.66  E-value: 5.64e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1314 TMIQLQNDKLKIMQEMKNSQQEHRNMENKTLELELKLKGLEELISTLKDARGAQKVINWHVKIEELRLQELKLNRELVKG 1393
Cdd:pfam16574    1 TMIQLQEDKAKLQEELKHAEEERRRAEDRAQELELKLKGLEELISTLKDGKGAQKVTEWHKKMEEIRLQELKLQRELSKQ 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 568967308  1394 KEEIKYLNNIISEYEHTINSLEEEIVQQSKFHEERQMAWDQREVELER 1441
Cdd:pfam16574   81 KEEIKYLENLIREQERTISSLEEEIVQQTKLHEERQLAWDQREVELER 128
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1107-1882 2.57e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.25  E-value: 2.57e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1107 HLRTSLKQMEERNFELETKFTELTKINLDAQKVEQMLRDELADSVTKavsdadRQRILELEKSEVELKVEVSKLREISDI 1186
Cdd:TIGR02168  226 ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEEL------RLEVSELEEEIEELQKELYALANEISR 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1187 AKRQVDFLNSQQQSREKEVESLRTQLLDFQAQSDEKALIAKlhqhvvSLQISEATALGKLESVTSKLQKMEAYNLRLEQK 1266
Cdd:TIGR02168  300 LEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA------ELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1267 LDEKEQALYYARlegrNRAKHLRQTIQSLRrqfsgalplAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEL 1346
Cdd:TIGR02168  374 LEELEEQLETLR----SKVAQLELQIASLN---------NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQA 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1347 ELKLKGLEELISTLKDARGAQKVINWHVKIEELRLQELKLNRELVKGKEEIKYLNNIISEYEHTINSLEEEIVQQSKFHE 1426
Cdd:TIGR02168  441 ELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSG 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1427 ERQMAWDQREV----ELERQLDIFDHQQNEILSAAQKFEDSTGSMPDPSLPLPNQLE---IALRKIKENIQVILKTQATC 1499
Cdd:TIGR02168  521 ILGVLSELISVdegyEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPldsIKGTEIQGNDREILKNIEGF 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1500 KSLEEKLKEKESALRLAEQNILSRDKVINELR--LRLPATADREKLIAELERKELEPKSHHTMKiAHQTIANMQARLNHK 1577
Cdd:TIGR02168  601 LGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDnaLELAKKLRPGYRIVTLDGDLVRPGGVITGG-SAKTNSSILERRREI 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1578 EEVLKKYQHLLEKAREEQREIVkkheedlhvlhhKLEQQADNSLNKFRQTAQDLLKQSPAPVPTNKHFIRLAEMEQTVAE 1657
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALA------------ELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEE 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1658 QDDSLSSLLTKLKKVSKDLEKQKEITELKVREFENTKLRLQEthasEVKKVKAEVEDLRHALAQAHKDSQSLKSELQAQK 1737
Cdd:TIGR02168  748 RIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA----QIEQLKEELKALREALDELRAELTLLNEEAANLR 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1738 E--ANSRAPTTTMRNLVDRLKSQLALKEKQQKALSRALLELRSEMtAAAEERIIAVTSQKEANLNVQQVVERHTRELKSQ 1815
Cdd:TIGR02168  824 ErlESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELI-EELESELEALLNERASLEEALALLRSELEELSEE 902

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568967308  1816 IEDLNENLLKLKEALKTSKNKENSLADDLNELNNELQKKQKAYNK--------ILREKDGIDQENDELRRQIKRL 1882
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEeysltleeAEALENKIEDDEEEARRRLKRL 977
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1648-2365 8.54e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 8.54e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1648 LAEMEQTVAEQDDSLSSLLTKLKKVSKDLEKQKEITEL--------------KVREFENTKLRLQ---ETHASEVKKVKA 1710
Cdd:TIGR02168  188 LDRLEDILNELERQLKSLERQAEKAERYKELKAELRELelallvlrleelreELEELQEELKEAEeelEELTAELQELEE 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1711 EVEDLRHALAQAHKDSQSLKSELQAQKEANSRaptttMRNLVDRLKSQLALKEKQQKALSRALLELRSEMTAAAEERIIA 1790
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQKELYALANEISR-----LEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEL 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1791 VTSQKEANLNVQQVVERHTrELKSQIEDLNENLLKLKEALKTSKNKENSLADDLNELNNELQKKQKAYNKILREKDGIDQ 1870
Cdd:TIGR02168  343 EEKLEELKEELESLEAELE-ELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1871 ENDELRRQIKRLSSGLQSKTLiDNKQSLIDELQKKVKKLESQLERKVDDVDIKPVKEKSSKEEL----IRWEEGKKWQTK 1946
Cdd:TIGR02168  422 EIEELLKKLEEAELKELQAEL-EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELaqlqARLDSLERLQEN 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1947 VEGLRNRLKEKEGEAHGLAKQLNTLKELF----------------------------AKADKEKLTLQKKLKTTGMTVDQ 1998
Cdd:TIGR02168  501 LEGFSEGVKALLKNQSGLSGILGVLSELIsvdegyeaaieaalggrlqavvvenlnaAKKAIAFLKQNELGRVTFLPLDS 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1999 VLGVRALESEKELEELKKKNLDLENDILYMRT------QQALPRDSVVEDL----HLQNKY-LQEKLHTLEKKL------ 2061
Cdd:TIGR02168  581 IKGTEIQGNDREILKNIEGFLGVAKDLVKFDPklrkalSYLLGGVLVVDDLdnalELAKKLrPGYRIVTLDGDLvrpggv 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2062 ----SKEKYSQSLTSEIESDDHCQK-------EQELQKENLKLSSENIELKFQLEQANKDLPRLKNQVKDLKEMCEFLKK 2130
Cdd:TIGR02168  661 itggSAKTNSSILERRREIEELEEKieeleekIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA 740

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2131 GKLELERKLGQ-----VRGAGRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKAsgiltSEKMATIEEENRNLKAELEKL 2205
Cdd:TIGR02168  741 EVEQLEERIAQlskelTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQL-----KEELKALREALDELRAELTLL 815

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2206 KAHFGRQLSMQFESKNKGTEKIVaENERLRKELKKEIEASEKLRIAKNNLELVNDKMAAQLEETGKRLQFAESRAPQLEG 2285
Cdd:TIGR02168  816 NEEAANLRERLESLERRIAATER-RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRS 894

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2286 ADSKSWKSIvvsRVYETKMKELESDIAKKNQSITDLKQLVREAT-EREQKAKKYTEDLEQQIEILKNVPEGAETEQELIR 2364
Cdd:TIGR02168  895 ELEELSEEL---RELESKRSELRRELEELREKLAQLELRLEGLEvRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEAR 971


                   .
gi 568967308  2365 E 2365
Cdd:TIGR02168  972 R 972
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 93-781 8.61e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 8.61e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308    93 KLENELEMAQQSAGGRDTRFLRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENENSKLRRENEQLRQD 172
Cdd:TIGR02168  217 ELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   173 IIDYQKQIDSQKESLlsrrgedSDYRSQLSKKNYELVQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNR 252
Cdd:TIGR02168  297 ISRLEQQKQILRERL-------ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   253 MKALVHQSDAVMDQIKKENEHYRLQVRELtdllkakdeeddpvmmavNAKVEEWKLILSSKDDEIIEYQQMLQSLRGKLK 332
Cdd:TIGR02168  370 LESRLEELEEQLETLRSKVAQLELQIASL------------------NNEIERLEARLERLEDRRERLQQEIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   333 NAQLDADKSNIMALKQGIQERDSQIKMLTEQVEQYTKEMEKNTFIIEDLKNELQKDKG--TSNFYQQTHYMKIHSKVQIL 410
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQArlDSLERLQENLEGFSEGVKAL 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   411 EEKTKEAE----RIAELAEADAR------------------EKDKELVEALKRLKDYESG------VYGLEDAVIEIKNC 462
Cdd:TIGR02168  512 LKNQSGLSgilgVLSELISVDEGyeaaieaalggrlqavvvENLNAAKKAIAFLKQNELGrvtflpLDSIKGTEIQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   463 KAQIKIRD--GEMEVLTKEINKLEMKINDIL-------DENEALRERAGLEPKTMI-----DL----------TEFRNSK 518
Cdd:TIGR02168  592 EILKNIEGflGVAKDLVKFDPKLRKALSYLLggvlvvdDLDNALELAKKLRPGYRIvtldgDLvrpggvitggSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   519 RLKQQQYRAENQVLLKEIES----LEEERLDLKRKIRQMAQE-RGKRNAASGLTIDDLNLSETFSHENKIEGRKLNFMSL 593
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEkiaeLEKALAELRKELEELEEElEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   594 NNMNETQSKNETIVQDLPIQEEQSRNAELELDHQRSQAEQNEF------LSRELAEKEKDLERSRTVIAKFQSKLKELVE 667
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLkeelkaLREALDELRAELTLLNEEAANLRERLESLER 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   668 ENKQLEEGMKEILQAIKDMpkdsdvkggetSLIIPSLERLVNAMESKNAEgifdaslhLKAQVDQLTGRNEELRQELRQS 747
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEEL-----------SEDIESLAAEIEELEELIEE--------LESELEALLNERASLEEALALL 892

                          730       740       750
                   ....*....|....*....|....*....|....
gi 568967308   748 RKEAVNYSQQLVKANLKIDHLEKETDLLRQSAGS 781
Cdd:TIGR02168  893 RSELEELSEELRELESKRSELRRELEELREKLAQ 926
PTZ00121 super family cl31754
MAEBL; Provisional
 814-1398 1.44e-03

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 1.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  814 QELDNKEKKLKHLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKDIWKTDSEMIREEKRKLED--QAEQDAVKVKEYNNLLS 891
Cdd:PTZ00121 1246 EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEakKKAEEAKKADEAKKKAE 1325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  892 ALQMDSNEMKKMLSENSRKITVLQVNEKSLIRQYTTLVEMER--HLRKENGKHRNDVIAMEAEVTEKLGSLQRFKEMAIF 969
Cdd:PTZ00121 1326 EAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEaaEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKK 1405

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  970 KIAALQKVidnsvslselELANKQYNELTTKYRDILQKDnmlvqrtsnlehlecenaSLKEQMEAISKELEItKEKLHTI 1049
Cdd:PTZ00121 1406 KADELKKA----------AAAKKKADEAKKKAEEKKKAD------------------EAKKKAEEAKKADEA-KKKAEEA 1456

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1050 EQAWEQETKLGNDSNMDKAKKSMTNSDIVSISKKITVLEMKELNERQRAEHCQKMYEHLRTSlkqmEERNFELETKFTEL 1129
Cdd:PTZ00121 1457 KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA----EEAKKADEAKKAEE 1532

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1130 TKINLDAQKVEQMLRdelADSVTKAVsdadrqrilELEKSEVELKVE-VSKLREISDIAKRQVDFLNSQQQSREKEVESL 1208
Cdd:PTZ00121 1533 AKKADEAKKAEEKKK---ADELKKAE---------ELKKAEEKKKAEeAKKAEEDKNMALRKAEEAKKAEEARIEEVMKL 1600

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1209 RTQLLDFQAQSDEKALIAKLHQHVVSLQISEATALGKLESVTSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHL 1288
Cdd:PTZ00121 1601 YEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEA 1680

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1289 RQTIQSLRRQFSGALPLAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRnmeNKTLELELKLKGLEELISTLKDARGAQK 1368
Cdd:PTZ00121 1681 KKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENK---IKAEEAKKEAEEDKKKAEEAKKDEEEKK 1757

                         570       580       590
                  ....*....|....*....|....*....|
gi 568967308 1369 VINWHVKIEELRLQELKLNRELVKgKEEIK 1398
Cdd:PTZ00121 1758 KIAHLKKEEEKKAEEIRKEKEAVI-EEELD 1786
 
Name Accession Description Interval E-value
CEP209_CC5 pfam16574
Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry ...
 1314-1441 5.64e-36

Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry a number of coiled-coil regions, and this is the fifth along the length of the protein. It is thought that the proteins are involved in cilia biosynthesis.


Pssm-ID: 465184 [Multi-domain]  Cd Length: 128  Bit Score: 133.66  E-value: 5.64e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1314 TMIQLQNDKLKIMQEMKNSQQEHRNMENKTLELELKLKGLEELISTLKDARGAQKVINWHVKIEELRLQELKLNRELVKG 1393
Cdd:pfam16574    1 TMIQLQEDKAKLQEELKHAEEERRRAEDRAQELELKLKGLEELISTLKDGKGAQKVTEWHKKMEEIRLQELKLQRELSKQ 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 568967308  1394 KEEIKYLNNIISEYEHTINSLEEEIVQQSKFHEERQMAWDQREVELER 1441
Cdd:pfam16574   81 KEEIKYLENLIREQERTISSLEEEIVQQTKLHEERQLAWDQREVELER 128
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1107-1882 2.57e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.25  E-value: 2.57e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1107 HLRTSLKQMEERNFELETKFTELTKINLDAQKVEQMLRDELADSVTKavsdadRQRILELEKSEVELKVEVSKLREISDI 1186
Cdd:TIGR02168  226 ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEEL------RLEVSELEEEIEELQKELYALANEISR 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1187 AKRQVDFLNSQQQSREKEVESLRTQLLDFQAQSDEKALIAKlhqhvvSLQISEATALGKLESVTSKLQKMEAYNLRLEQK 1266
Cdd:TIGR02168  300 LEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA------ELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1267 LDEKEQALYYARlegrNRAKHLRQTIQSLRrqfsgalplAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEL 1346
Cdd:TIGR02168  374 LEELEEQLETLR----SKVAQLELQIASLN---------NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQA 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1347 ELKLKGLEELISTLKDARGAQKVINWHVKIEELRLQELKLNRELVKGKEEIKYLNNIISEYEHTINSLEEEIVQQSKFHE 1426
Cdd:TIGR02168  441 ELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSG 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1427 ERQMAWDQREV----ELERQLDIFDHQQNEILSAAQKFEDSTGSMPDPSLPLPNQLE---IALRKIKENIQVILKTQATC 1499
Cdd:TIGR02168  521 ILGVLSELISVdegyEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPldsIKGTEIQGNDREILKNIEGF 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1500 KSLEEKLKEKESALRLAEQNILSRDKVINELR--LRLPATADREKLIAELERKELEPKSHHTMKiAHQTIANMQARLNHK 1577
Cdd:TIGR02168  601 LGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDnaLELAKKLRPGYRIVTLDGDLVRPGGVITGG-SAKTNSSILERRREI 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1578 EEVLKKYQHLLEKAREEQREIVkkheedlhvlhhKLEQQADNSLNKFRQTAQDLLKQSPAPVPTNKHFIRLAEMEQTVAE 1657
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALA------------ELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEE 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1658 QDDSLSSLLTKLKKVSKDLEKQKEITELKVREFENTKLRLQEthasEVKKVKAEVEDLRHALAQAHKDSQSLKSELQAQK 1737
Cdd:TIGR02168  748 RIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA----QIEQLKEELKALREALDELRAELTLLNEEAANLR 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1738 E--ANSRAPTTTMRNLVDRLKSQLALKEKQQKALSRALLELRSEMtAAAEERIIAVTSQKEANLNVQQVVERHTRELKSQ 1815
Cdd:TIGR02168  824 ErlESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELI-EELESELEALLNERASLEEALALLRSELEELSEE 902

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568967308  1816 IEDLNENLLKLKEALKTSKNKENSLADDLNELNNELQKKQKAYNK--------ILREKDGIDQENDELRRQIKRL 1882
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEeysltleeAEALENKIEDDEEEARRRLKRL 977
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1648-2365 8.54e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 8.54e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1648 LAEMEQTVAEQDDSLSSLLTKLKKVSKDLEKQKEITEL--------------KVREFENTKLRLQ---ETHASEVKKVKA 1710
Cdd:TIGR02168  188 LDRLEDILNELERQLKSLERQAEKAERYKELKAELRELelallvlrleelreELEELQEELKEAEeelEELTAELQELEE 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1711 EVEDLRHALAQAHKDSQSLKSELQAQKEANSRaptttMRNLVDRLKSQLALKEKQQKALSRALLELRSEMTAAAEERIIA 1790
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQKELYALANEISR-----LEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEL 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1791 VTSQKEANLNVQQVVERHTrELKSQIEDLNENLLKLKEALKTSKNKENSLADDLNELNNELQKKQKAYNKILREKDGIDQ 1870
Cdd:TIGR02168  343 EEKLEELKEELESLEAELE-ELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1871 ENDELRRQIKRLSSGLQSKTLiDNKQSLIDELQKKVKKLESQLERKVDDVDIKPVKEKSSKEEL----IRWEEGKKWQTK 1946
Cdd:TIGR02168  422 EIEELLKKLEEAELKELQAEL-EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELaqlqARLDSLERLQEN 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1947 VEGLRNRLKEKEGEAHGLAKQLNTLKELF----------------------------AKADKEKLTLQKKLKTTGMTVDQ 1998
Cdd:TIGR02168  501 LEGFSEGVKALLKNQSGLSGILGVLSELIsvdegyeaaieaalggrlqavvvenlnaAKKAIAFLKQNELGRVTFLPLDS 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1999 VLGVRALESEKELEELKKKNLDLENDILYMRT------QQALPRDSVVEDL----HLQNKY-LQEKLHTLEKKL------ 2061
Cdd:TIGR02168  581 IKGTEIQGNDREILKNIEGFLGVAKDLVKFDPklrkalSYLLGGVLVVDDLdnalELAKKLrPGYRIVTLDGDLvrpggv 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2062 ----SKEKYSQSLTSEIESDDHCQK-------EQELQKENLKLSSENIELKFQLEQANKDLPRLKNQVKDLKEMCEFLKK 2130
Cdd:TIGR02168  661 itggSAKTNSSILERRREIEELEEKieeleekIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA 740

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2131 GKLELERKLGQ-----VRGAGRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKAsgiltSEKMATIEEENRNLKAELEKL 2205
Cdd:TIGR02168  741 EVEQLEERIAQlskelTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQL-----KEELKALREALDELRAELTLL 815

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2206 KAHFGRQLSMQFESKNKGTEKIVaENERLRKELKKEIEASEKLRIAKNNLELVNDKMAAQLEETGKRLQFAESRAPQLEG 2285
Cdd:TIGR02168  816 NEEAANLRERLESLERRIAATER-RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRS 894

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2286 ADSKSWKSIvvsRVYETKMKELESDIAKKNQSITDLKQLVREAT-EREQKAKKYTEDLEQQIEILKNVPEGAETEQELIR 2364
Cdd:TIGR02168  895 ELEELSEEL---RELESKRSELRRELEELREKLAQLELRLEGLEvRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEAR 971


                   .
gi 568967308  2365 E 2365
Cdd:TIGR02168  972 R 972
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 93-781 8.61e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 8.61e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308    93 KLENELEMAQQSAGGRDTRFLRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENENSKLRRENEQLRQD 172
Cdd:TIGR02168  217 ELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   173 IIDYQKQIDSQKESLlsrrgedSDYRSQLSKKNYELVQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNR 252
Cdd:TIGR02168  297 ISRLEQQKQILRERL-------ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   253 MKALVHQSDAVMDQIKKENEHYRLQVRELtdllkakdeeddpvmmavNAKVEEWKLILSSKDDEIIEYQQMLQSLRGKLK 332
Cdd:TIGR02168  370 LESRLEELEEQLETLRSKVAQLELQIASL------------------NNEIERLEARLERLEDRRERLQQEIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   333 NAQLDADKSNIMALKQGIQERDSQIKMLTEQVEQYTKEMEKNTFIIEDLKNELQKDKG--TSNFYQQTHYMKIHSKVQIL 410
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQArlDSLERLQENLEGFSEGVKAL 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   411 EEKTKEAE----RIAELAEADAR------------------EKDKELVEALKRLKDYESG------VYGLEDAVIEIKNC 462
Cdd:TIGR02168  512 LKNQSGLSgilgVLSELISVDEGyeaaieaalggrlqavvvENLNAAKKAIAFLKQNELGrvtflpLDSIKGTEIQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   463 KAQIKIRD--GEMEVLTKEINKLEMKINDIL-------DENEALRERAGLEPKTMI-----DL----------TEFRNSK 518
Cdd:TIGR02168  592 EILKNIEGflGVAKDLVKFDPKLRKALSYLLggvlvvdDLDNALELAKKLRPGYRIvtldgDLvrpggvitggSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   519 RLKQQQYRAENQVLLKEIES----LEEERLDLKRKIRQMAQE-RGKRNAASGLTIDDLNLSETFSHENKIEGRKLNFMSL 593
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEkiaeLEKALAELRKELEELEEElEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   594 NNMNETQSKNETIVQDLPIQEEQSRNAELELDHQRSQAEQNEF------LSRELAEKEKDLERSRTVIAKFQSKLKELVE 667
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLkeelkaLREALDELRAELTLLNEEAANLRERLESLER 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   668 ENKQLEEGMKEILQAIKDMpkdsdvkggetSLIIPSLERLVNAMESKNAEgifdaslhLKAQVDQLTGRNEELRQELRQS 747
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEEL-----------SEDIESLAAEIEELEELIEE--------LESELEALLNERASLEEALALL 892

                          730       740       750
                   ....*....|....*....|....*....|....
gi 568967308   748 RKEAVNYSQQLVKANLKIDHLEKETDLLRQSAGS 781
Cdd:TIGR02168  893 RSELEELSEELRELESKRSELRRELEELREKLAQ 926
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1658-1939 5.33e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 5.33e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1658 QDDSLSSLLTKLKKVSKDLEKQKEITELKVREFENTKLRLQETHASEVKKVKAEVEDLRHALAQAHKDSQSLKSELQAQK 1737
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1738 EANSRAptttmrnlvDRLKSQLALKEKQQKALSRALLELRSEMTAAAEERIIAvtsqKEANLNVQQVVERHTRELKSQIE 1817
Cdd:COG1196   313 ELEERL---------EELEEELAELEEELEELEEELEELEEELEEAEEELEEA----EAELAEAEEALLEAEAELAEAEE 379

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1818 DLNENLLKLKEALKTSKNKENSLADDLNELNNELQKKQKAYNKILREKDGIDQENDELRRQIKRLSSGLQSKTLIDNKQS 1897
Cdd:COG1196   380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 568967308 1898 LIDELQKKVKKLESQLERKVDDVDIKPVKEKSSKEELIRWEE 1939
Cdd:COG1196   460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEA 501
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 113-686 8.13e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.49  E-value: 8.13e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  113 LRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENENSKLRRENEQLRQDIIDYQKQIDSQKESLLSRRG 192
Cdd:COG1196   244 LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEE 323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  193 EDSDYRSQLSKKNYELVQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKALVHQSDAVMDQIKKENE 272
Cdd:COG1196   324 ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  273 HYRLQVRELTDLLKAKDEEddpvmmavnakVEEWKLILSSKDDEIIEYQQMLQSLRGKLKNAQLDAdKSNIMALKQGIQE 352
Cdd:COG1196   404 ELEEAEEALLERLERLEEE-----------LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE-EALLELLAELLEE 471

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  353 RDSQIKMLTEQVEQYTKEMEKNTFIIEDLKNELQKDKGTSNFYQQTHYMKIHSKVQILEEKTKEAERIAELAEADA---- 428
Cdd:COG1196   472 AALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAAlqni 551

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  429 -REKDKELVEALKRLKDYESG-------------------------VYGLEDAVIEIKNCKAQIKIRDGEMEVLTKEINK 482
Cdd:COG1196   552 vVEDDEVAAAAIEYLKAAKAGratflpldkiraraalaaalargaiGAAVDLVASDLREADARYYVLGDTLLGRTLVAAR 631

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  483 LEMKINDILDENEALRERAGLEPKTMIDLTEFRNSKRLKQQQYRAENQVLLKEIESLEEERLDLKRKIRQMAQERGKRNA 562
Cdd:COG1196   632 LEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAE 711

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  563 ASGLTIDDLNLSEtfshenkiegrklnfmslnnmNETQSKNETIVQDLPIQEEQSRNAELELDHQRSQAEQNEFLSRELA 642
Cdd:COG1196   712 AEEERLEEELEEE---------------------ALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568967308  643 EKEKDLERSRTV----IAKFQS---KLKELVEENKQLEEGMKEILQAIKDM 686
Cdd:COG1196   771 RLEREIEALGPVnllaIEEYEEleeRYDFLSEQREDLEEARETLEEAIEEI 821
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 518-1300 2.98e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.69  E-value: 2.98e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   518 KRLKQQQYRAENQVLLKEIESLEEERLDLKRKIRQMAQERGKRNAASGLTIDDLNLSETFSHENKIEGRKLNfMSLNNMN 597
Cdd:TIGR02168  216 KELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQ-KELYALA 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   598 ETQSKNETIVQDLPIQEEQSRNAELELDHQRSQAEQ-NEFLSRELAEKEKDLERSRTVIAKFQSKLKELVEENKQLEEGM 676
Cdd:TIGR02168  295 NEISRLEQQKQILRERLANLERQLEELEAQLEELESkLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   677 KEILQAIKDMPKDSDVKGGETSLIIPSLERLvnamesknaegifdaslhlKAQVDQLTGRNEELRQELRQSRKEAVNYSQ 756
Cdd:TIGR02168  375 EELEEQLETLRSKVAQLELQIASLNNEIERL-------------------EARLERLEDRRERLQQEIEELLKKLEEAEL 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   757 QLVKANLKIDHLEKETDLLRQSAGsnvvykgidlpdgiapssayiinsqNEYLIHLLQELDNKEKKLKHLEDSLEDYNRK 836
Cdd:TIGR02168  436 KELQAELEELEEELEELQEELERL-------------------------EEALEELREELEEAEQALDAAERELAQLQAR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   837 FAVIRHQQSLLYKEYLSEKDIWKTdsemirEEKRKLEDQAEQDAVKV-KEYNNLLSALQMDSNEMKKMLSENSRKITVLQ 915
Cdd:TIGR02168  491 LDSLERLQENLEGFSEGVKALLKN------QSGLSGILGVLSELISVdEGYEAAIEAALGGRLQAVVVENLNAAKKAIAF 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   916 VNEKSLIRQyTTLVEMERHLRKENGKHRNdviaMEAEVTEKLGSLQRFKEMAIFKIAALQKVIDNSVSLSELELANKQYN 995
Cdd:TIGR02168  565 LKQNELGRV-TFLPLDSIKGTEIQGNDRE----ILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAK 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   996 ELTTKYRDI-----------------LQKDNMLVQRTSNLEHLECENASLKEQMEAISKELEITKEKLHTIEQAWEQETK 1058
Cdd:TIGR02168  640 KLRPGYRIVtldgdlvrpggvitggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRK 719

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1059 LGNDsnmdkakksmtnsdivsISKKITVLEMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELETKFTELTKiNLDAQK 1138
Cdd:TIGR02168  720 ELEE-----------------LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE-ELAEAE 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1139 VEQMLRDELADSVTKAVSdADRQRILELEKSEVELKVEVSKLREISDIAKRQVDFLNSQQQSREKEVESLRTQLLDFQAQ 1218
Cdd:TIGR02168  782 AEIEELEAQIEQLKEELK-ALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE 860

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1219 -SDEKALIAKLHQHVVSLQISEATALGKLESVTSKLQKMEAYNLRLEQKLDEKEQALYYARL---EGRNRAKHLRQTIQS 1294
Cdd:TIGR02168  861 iEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREklaQLELRLEGLEVRIDN 940


                   ....*.
gi 568967308  1295 LRRQFS 1300
Cdd:TIGR02168  941 LQERLS 946
PTZ00121 PTZ00121
MAEBL; Provisional
 1763-2411 1.27e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 54.38  E-value: 1.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1763 EKQQKALSRALLELRSEMTAAAEERIIAVTSQKEANLNVQQvvERHTRELKSQIEDLNENLLKLKEALKTS-----KNKE 1837
Cdd:PTZ00121 1236 KKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEE--ARKADELKKAEEKKKADEAKKAEEKKKAdeakkKAEE 1313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1838 NSLADDLNELNNELQKKQKAYNKILREKDGIDQENDELRRQIKRLSSGLQSKTLIDNKQSliDELQKKVKKLESQLE--R 1915
Cdd:PTZ00121 1314 AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKK--EEAKKKADAAKKKAEekK 1391

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1916 KVDDVDIKPVKEKSSKEELIRWEEGKKwqtkveglrnrlkeKEGEAHGLAKQLNTLKELFAKADKEKLTLQKKLKTTGMT 1995
Cdd:PTZ00121 1392 KADEAKKKAEEDKKKADELKKAAAAKK--------------KADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAK 1457

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1996 VDQVLGVRALESEKELEELKKKNLDLENDILYMRTQQALPRDSVVEDLHLQNKYLQEKLHTLEKKLSKE---KYSQSLTS 2072
Cdd:PTZ00121 1458 KAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEakkAEEAKKAD 1537

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2073 EIESDDHCQKEQELQK-ENLKLSSE--NIELKFQLEQANKDLPRLKNQVKDLKE--MCEFLKKGKLELERKLGQVRGAGR 2147
Cdd:PTZ00121 1538 EAKKAEEKKKADELKKaEELKKAEEkkKAEEAKKAEEDKNMALRKAEEAKKAEEarIEEVMKLYEEEKKMKAEEAKKAEE 1617

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2148 SGKTIPELEKTIGLMKKVVEKVQRENEQLKKASGILTSEKMATIEEENRNLKAELEKLKAhfgRQLSMQFESKNKGTEKI 2227
Cdd:PTZ00121 1618 AKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKA---EEAKKAEEDEKKAAEAL 1694

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2228 VAENERLRK-ELKKEIEASEKlriaknnlelvndKMAAQLEETGKRLQFAESRAPQLEGADSKSWKSIVVSRVYETKMKE 2306
Cdd:PTZ00121 1695 KKEAEEAKKaEELKKKEAEEK-------------KKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAH 1761

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2307 LESDIAKKNQSITDLKQLV------REATEREQKAKKYTEDLEQQIEIL-----KNVPEGAETEQELIRELQLLRLANNq 2375
Cdd:PTZ00121 1762 LKKEEEKKAEEIRKEKEAVieeeldEEDEKRRMEVDKKIKDIFDNFANIieggkEGNLVINDSKEMEDSAIKEVADSKN- 1840

                         650       660       670
                  ....*....|....*....|....*....|....*.
gi 568967308 2376 MDKERAELIHQIEINKDQTRADSSIPDSDQLKEKIN 2411
Cdd:PTZ00121 1841 MQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDL 1876
PRK11281 PRK11281
mechanosensitive channel MscK;
1660-1912 2.24e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 53.38  E-value: 2.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1660 DSLSSLLTKLKKvSKDLEKQKEITelkVREFENTKLRLQEThasevKKVKAEVEDLRHALAQAHKDSQSLKSELQAQKEA 1739
Cdd:PRK11281   39 ADVQAQLDALNK-QKLLEAEDKLV---QQDLEQTLALLDKI-----DRQKEETEQLKQQLAQAPAKLRQAQAELEALKDD 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1740 NSRAPTTTMRNL-VDRLKSQLALKEKQQKALSRALLELRSEMTAA--AEERiiavtSQKEANLNVQQvverhTRELKSQI 1816
Cdd:PRK11281  110 NDEETRETLSTLsLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLqtQPER-----AQAALYANSQR-----LQQIRNLL 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1817 EDLNENLLKLKEALKTSKNKENSLADdlneLNNELQKKQKAYNKILreKDGIDQENDELRRQIKRLSSGLQS-KTLIDNK 1895
Cdd:PRK11281  180 KGGKVGGKALRPSQRVLLQAEQALLN----AQNDLQRKSLEGNTQL--QDLLQKQRDYLTARIQRLEHQLQLlQEAINSK 253

                         250
                  ....*....|....*..
gi 568967308 1896 QslIDELQKKVKKLESQ 1912
Cdd:PRK11281  254 R--LTLSEKTVQEAQSQ 268
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 429-685 9.59e-06

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 51.08  E-value: 9.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  429 REKDKELVEALkrlkdYESGVYGLEDAVIEIKNckaqikirdgemEVLTKEINKLeMKINDILDENEALRERAGLEPKTM 508
Cdd:PRK05771   15 KSYKDEVLEAL-----HELGVVHIEDLKEELSN------------ERLRKLRSLL-TKLSEALDKLRSYLPKLNPLREEK 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  509 IDLTEFRNSKRLKQQQYRAENqvLLKEIESLEEERLDLKRKIRQMAQERG--KRNAASGLTIDDLNLSETFS------HE 580
Cdd:PRK05771   77 KKVSVKSLEELIKDVEEELEK--IEKEIKELEEEISELENEIKELEQEIErlEPWGNFDLDLSLLLGFKYVSvfvgtvPE 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  581 NKIEGRKLNFMSLNNMNETQSKNETIV------QDLPIQEEQSRNAE---LELDHQRSQAEQNEFLSRELAEKEKDLERS 651
Cdd:PRK05771  155 DKLEELKLESDVENVEYISTDKGYVYVvvvvlkELSDEVEEELKKLGferLELEEEGTPSELIREIKEELEEIEKERESL 234

                         250       260       270
                  ....*....|....*....|....*....|....
gi 568967308  652 RtviakfqSKLKELVEENKQLEEGMKEILQAIKD 685
Cdd:PRK05771  235 L-------EELKELAKKYLEELLALYEYLEIELE 261
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1755-2421 1.24e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 1.24e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1755 LKSQLALKEKQQKALSRALlELRSEmtaaAEERiiavtsQKEANLNVQQVVERHTRELKSQIEDLNENLLKLKEALKTSK 1834
Cdd:COG1196   198 LERQLEPLERQAEKAERYR-ELKEE----LKEL------EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELE 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1835 NKENSLADDLNELNNELQKKQKAYNKILREKDGIDQENDELRRQIKRLssglqsktlidnkQSLIDELQKKVKKLESQLE 1914
Cdd:COG1196   267 AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL-------------EERLEELEEELAELEEELE 333

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1915 RKvddvdikpvkekssKEELIRWEEgkkwqtkveglrnRLKEKEGEAHGLAKQLNTLKELFAKADKEKLTLQKklkttgm 1994
Cdd:COG1196   334 EL--------------EEELEELEE-------------ELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE------- 379

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1995 tvdqvlgvRALESEKELEELKKKNLDLENDILYMRTQQAlprdsvvEDLHLQNKYLQEKlhtlekklsKEKYSQSLTSEI 2074
Cdd:COG1196   380 --------ELEELAEELLEALRAAAELAAQLEELEEAEE-------ALLERLERLEEEL---------EELEEALAELEE 435

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2075 ESDDHCQKEQELQKENLKLSSENIELKFQLEQANKDLPRLKNQVKDLKEMCEFLKKGKLELERKLGQVRGAGRSGKTIPE 2154
Cdd:COG1196   436 EEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALL 515

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2155 LEKTIGLMKKVVEKVQRENEQLKKASGILTSEKMATIEEENRNLKAELEKLKAHFGRQLSmqFESKNKGTEKIVAENERL 2234
Cdd:COG1196   516 LAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAT--FLPLDKIRARAALAAALA 593

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2235 RKELKKEIEASEKLRIAKNNLELVNDKMAAQLEETGKRLQFAESRAPQLEGADSKswKSIVVSRVYETKMKELESDIAKK 2314
Cdd:COG1196   594 RGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLRE--VTLEGEGGSAGGSLTGGSRRELL 671

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2315 NQSITDLKQLVREATEREQKAKKYTEDLEQQIEILKnvpEGAETEQELIRELQLLRLANNQMDKERAELIHQIEINKDQT 2394
Cdd:COG1196   672 AALLEAEAELEELAERLAEEELELEEALLAEEEEER---ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELL 748

                         650       660       670
                  ....*....|....*....|....*....|..
gi 568967308 2395 RAD-----SSIPDSDQLKEKINDLETQLRKLE 2421
Cdd:COG1196   749 EEEaleelPEPPDLEELERELERLEREIEALG 780
Mitofilin pfam09731
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ...
 1583-1987 1.38e-05

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.


Pssm-ID: 430783 [Multi-domain]  Cd Length: 618  Bit Score: 50.53  E-value: 1.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1583 KYQHLLEKAREEQREIVKKHEEDLHVLHHKLEQQADnslnKFRQTAQDLLKQSPAPVPTNKHFIRLAEMEQTVA------ 1656
Cdd:pfam09731   31 NFRDFFEEYIPYGEEVVLYALGEDPPLAPKPKTFRP----LQPSVVSAVTGESKEPKEEKKQVKIPRQSGVSSEvaeeek 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1657 -EQDDSLSSLLTKLKKVSKDLEKQKEITELKVREFENTKLRLQETHASEVKKVKAEVEDLRHALAQAHKDSQSLKSELQA 1735
Cdd:pfam09731  107 eATKDAAEAKAQLPKSEQEKEKALEEVLKEAISKAESATAVAKEAKDDAIQAVKAHTDSLKEASDTAEISREKATDSALQ 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1736 QKEANSRAPTTTM----RNLVDRLKSQLALKEKQQKALSRALLELRSEMTAAAEERIIAVTSQKEANLNVQQVVerhtRE 1811
Cdd:pfam09731  187 KAEALAEKLKEVInlakQSEEEAAPPLLDAAPETPPKLPEHLDNVEEKVEKAQSLAKLVDQYKELVASERIVFQ----QE 262

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1812 LKSQIEDLNENLlklKEALKTSKNKENSLAD----DLNELNNELQKKQKAYNKilREKDGIDQENDELRRQIKRLSSGLQ 1887
Cdd:pfam09731  263 LVSIFPDIIPVL---KEDNLLSNDDLNSLIAhahrEIDQLSKKLAELKKREEK--HIERALEKQKEELDKLAEELSARLE 337

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1888 SKTLIDNKQsLIDELQKKV--------KKLESQLERKVDDVDIKPVKEKSSKEELIRWEEGKKWQTKVEGLRNRLKEKEG 1959
Cdd:pfam09731  338 EVRAADEAQ-LRLEFEREReeiresyeEKLRTELERQAEAHEEHLKDVLVEQEIELQREFLQDIKEKVEEERAGRLLKLN 416

                          410       420
                   ....*....|....*....|....*...
gi 568967308  1960 EAHGLAKQLNTLKELFAKADKEKLTLQK 1987
Cdd:pfam09731  417 ELLANLKGLEKATSSHSEVEDENRKAQQ 444
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 113-894 7.06e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 45.35  E-value: 7.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   113 LRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENENSKLRRENEQLRQDIIDYQKQIDSQKESLLSRRG 192
Cdd:pfam02463  192 LEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVL 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   193 EDSDYRSQLSK-KNYELVQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKALVHQSDAVMDQIKKEN 271
Cdd:pfam02463  272 KENKEEEKEKKlQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKR 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   272 EHYRLQVRELTDLLKAKDEEDDPVMMAVNAKVEEwklilSSKDDEIIEYQQMLQSLRGKLKNAQLDADKSNIMALKQGIQ 351
Cdd:pfam02463  352 EAEEEEEEELEKLQEKLEQLEEELLAKKKLESER-----LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKK 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   352 ERDSQIKMLTEqveqyTKEMEKNTFIIEDLKNELQKDKGTSNFYQQTHYMKIHSKVQILEEKTKEAERIAELAEADAREK 431
Cdd:pfam02463  427 EELEILEEEEE-----SIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQK 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   432 DKELVEALKRLKDYESGVYGLEDAVIEIKNCKAQIKIRDGEMEVLTKEINKLEMKIndILDENEALRERAGLEPKTMIDL 511
Cdd:pfam02463  502 ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATA--DEVEERQKLVRALTELPLGARK 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   512 TEFRNSKRLKQQQYRAENQVLLKEIESLEEERLDLKRKIRQMAQERGK--RNAASGLTIDDLNLSETFSHENKIEGRKLN 589
Cdd:pfam02463  580 LRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGilKDTELTKLKESAKAKESGLRKGVSLEEGLA 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   590 FMSLNNMNETQSKNETIVQDLPIQEEQSRNAELELdHQRSQAEQNEFLSRELAEKEKDLERSRTVIAKFQSKLKELVEEN 669
Cdd:pfam02463  660 EKSEVKASLSELTKELLEIQELQEKAESELAKEEI-LRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEEL 738

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   670 KQLEEGMKEILQAIKDMPKDSDVKGGETSLIIPSLERLVNAMESKNAEGIFDASLH-LKAQVDQLTGRNEELRQELRQSR 748
Cdd:pfam02463  739 KLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEkLKAQEEELRALEEELKEEAELLE 818

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   749 KEAVNYSQQLVKANLKIDHLEKETDLLRQSAGSNVVYKGIDLpdgiAPSSAYIINSQNEYLIHLLQELDNKEKKLKHLED 828
Cdd:pfam02463  819 EEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLE----EEITKEELLQELLLKEEELEEQKLKDELESKEEK 894

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568967308   829 SLEDYNRKFAVIRHQQSLLYKEYLSEKDIWKTDSEMIREEKRKLEDQAEQDAVKVKEYNNLLSALQ 894
Cdd:pfam02463  895 EKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEE 960
PTZ00121 PTZ00121
MAEBL; Provisional
 814-1398 1.44e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 1.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  814 QELDNKEKKLKHLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKDIWKTDSEMIREEKRKLED--QAEQDAVKVKEYNNLLS 891
Cdd:PTZ00121 1246 EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEakKKAEEAKKADEAKKKAE 1325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  892 ALQMDSNEMKKMLSENSRKITVLQVNEKSLIRQYTTLVEMER--HLRKENGKHRNDVIAMEAEVTEKLGSLQRFKEMAIF 969
Cdd:PTZ00121 1326 EAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEaaEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKK 1405

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  970 KIAALQKVidnsvslselELANKQYNELTTKYRDILQKDnmlvqrtsnlehlecenaSLKEQMEAISKELEItKEKLHTI 1049
Cdd:PTZ00121 1406 KADELKKA----------AAAKKKADEAKKKAEEKKKAD------------------EAKKKAEEAKKADEA-KKKAEEA 1456

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1050 EQAWEQETKLGNDSNMDKAKKSMTNSDIVSISKKITVLEMKELNERQRAEHCQKMYEHLRTSlkqmEERNFELETKFTEL 1129
Cdd:PTZ00121 1457 KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA----EEAKKADEAKKAEE 1532

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1130 TKINLDAQKVEQMLRdelADSVTKAVsdadrqrilELEKSEVELKVE-VSKLREISDIAKRQVDFLNSQQQSREKEVESL 1208
Cdd:PTZ00121 1533 AKKADEAKKAEEKKK---ADELKKAE---------ELKKAEEKKKAEeAKKAEEDKNMALRKAEEAKKAEEARIEEVMKL 1600

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1209 RTQLLDFQAQSDEKALIAKLHQHVVSLQISEATALGKLESVTSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHL 1288
Cdd:PTZ00121 1601 YEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEA 1680

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1289 RQTIQSLRRQFSGALPLAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRnmeNKTLELELKLKGLEELISTLKDARGAQK 1368
Cdd:PTZ00121 1681 KKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENK---IKAEEAKKEAEEDKKKAEEAKKDEEEKK 1757

                         570       580       590
                  ....*....|....*....|....*....|
gi 568967308 1369 VINWHVKIEELRLQELKLNRELVKgKEEIK 1398
Cdd:PTZ00121 1758 KIAHLKKEEEKKAEEIRKEKEAVI-EEELD 1786
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 624-1444 4.04e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.74  E-value: 4.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   624 LDHQRSQAEQNEFLSRELAEKEK-----DLERSRTVIAKFQSKLKELVEENKQLEEGMKEILQAIKdmpkdsdvkggETS 698
Cdd:TIGR02168  205 LERQAEKAERYKELKAELRELELallvlRLEELREELEELQEELKEAEEELEELTAELQELEEKLE-----------ELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   699 LIIPSLERLVNAMESKNAEgifdaslhLKAQVDQLTGRNEELRQELRQSRKEAVNYSQQLVKANLKIDHLEKETDLLRQS 778
Cdd:TIGR02168  274 LEVSELEEEIEELQKELYA--------LANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEK 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   779 AGSnvvykgidlpdgiapsSAYIINSQNEYLIHLLQELDNKEKKLKHLEDSLEDYNRKFAVIRHQQSLLykeylsEKDIW 858
Cdd:TIGR02168  346 LEE----------------LKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL------NNEIE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   859 KTDSEMIREEKRKLEDQAEQDAVKVKEYNNLLSALQMDSNEMKKMLSENSRKITVLQVNEKSLIRQYTTLVEMERHLRKE 938
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERE 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   939 NGKHRNDVIAMEAEVTEKLGSLQRFKE--MAIFKIAALQKVIDNSVSL-SELELA-------NKQY---NELTTKYRDI- 1004
Cdd:TIGR02168  484 LAQLQARLDSLERLQENLEGFSEGVKAllKNQSGLSGILGVLSELISVdEGYEAAieaalggRLQAvvvENLNAAKKAIa 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1005 ------LQKDNMLVQRTSNLEHLECENASLKEQME---AISKELEITKEKLHTIEQAWEQETKLGND--SNMDKAKKSMT 1073
Cdd:TIGR02168  564 flkqneLGRVTFLPLDSIKGTEIQGNDREILKNIEgflGVAKDLVKFDPKLRKALSYLLGGVLVVDDldNALELAKKLRP 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1074 NSDIVS-----------ISKKITVLEMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELETKFTELTKINLDAQKVEQM 1142
Cdd:TIGR02168  644 GYRIVTldgdlvrpggvITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1143 LRDELADsvTKAVSDADRQRILELEKSEVELKVEVSKLREISDIAKRQVDFLNSQQQSREKEVESLRTQLLDFQAQ-SDE 1221
Cdd:TIGR02168  724 LSRQISA--LRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEElKAL 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1222 KALIAKLHQHVVSLQISEATALGKLESVTSKLQKMEAYNLRLEQKLDEKEQALyyarlegrNRAKHLRQTIQSLRRQFSG 1301
Cdd:TIGR02168  802 REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDI--------ESLAAEIEELEELIEELES 873

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1302 ALplaqqEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKtlelelklkgleelistLKDARGAQKVINWHVKIEELRL 1381
Cdd:TIGR02168  874 EL-----EALLNERASLEEALALLRSELEELSEELRELESK-----------------RSELRRELEELREKLAQLELRL 931

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568967308  1382 QELKLNRELVKGKeeikylnnIISEYEHTinslEEEIVQQSKFHEERQMAWDQREVELERQLD 1444
Cdd:TIGR02168  932 EGLEVRIDNLQER--------LSEEYSLT----LEEAEALENKIEDDEEEARRRLKRLENKIK 982
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 575-1257 8.49e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 41.64  E-value: 8.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   575 ETFSHENKIEGRKLNfmSLNNMNETQS---KNETIVQDLPIQEEQ-SRNAELELDHQRSQAEQNefLSRELAEKEKDLER 650
Cdd:pfam15921   81 EEYSHQVKDLQRRLN--ESNELHEKQKfylRQSVIDLQTKLQEMQmERDAMADIRRRESQSQED--LRNQLQNTVHELEA 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   651 SRTVIAKFQSKLKELVEENKQLEEGMKEILQAIKDMPKDSDVKGGETsliIPSLERLVNAMESKNAEGIFDASLHLKAQV 730
Cdd:pfam15921  157 AKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKK---IYEHDSMSTMHFRSLGSAISKILRELDTEI 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   731 DQLTGRNEELRQELRQSRKEAVNYSQQLVKANL-KIDHLEKE-----TDLLRQSAGSNVVYKGIDLPDGIAPSSAyiiNS 804
Cdd:pfam15921  234 SYLKGRIFPVEDQLEALKSESQNKIELLLQQHQdRIEQLISEheveiTGLTEKASSARSQANSIQSQLEIIQEQA---RN 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   805 QNEYLIHLLQELDNKEKKLK-HLEDSLEDYNRKFAVIRHQQSLLYKEyLSEKdiwKTDSEMIREEKRKLEDQ-------- 875
Cdd:pfam15921  311 QNSMYMRQLSDLESTVSQLRsELREAKRMYEDKIEELEKQLVLANSE-LTEA---RTERDQFSQESGNLDDQlqklladl 386

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   876 --AEQDAVKVKEYNNLLSALQMDS----NEMKKMLSENSRKITVLQVNEKSLIRQYTTlvEMERHLRKENGKhrNDVIAM 949
Cdd:pfam15921  387 hkREKELSLEKEQNKRLWDRDTGNsitiDHLRRELDDRNMEVQRLEALLKAMKSECQG--QMERQMAAIQGK--NESLEK 462

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   950 EAEVTEKLGSLQRFKEMAIFKIAALQKVIDNS--------VSLSELELANKQYNELTTKYRD----ILQKDNMLVQRTSN 1017
Cdd:pfam15921  463 VSSLTAQLESTKEMLRKVVEELTAKKMTLESSertvsdltASLQEKERAIEATNAEITKLRSrvdlKLQELQHLKNEGDH 542

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1018 LEHLECENASLKEQMEAISKELEITKEKLHTIEQAWEQETKLGNDSNMDKAKKSMTNSDivsisKKITVLEMKELNERQR 1097
Cdd:pfam15921  543 LRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEIND-----RRLELQEFKILKDKKD 617

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1098 AEhcqkmyehlrtsLKQMEERNFELETKFTELTKIN---LDAQKVEQMLRDELADSVTKAVSdadrqrilELEKSEVELK 1174
Cdd:pfam15921  618 AK------------IRELEARVSDLELEKVKLVNAGserLRAVKDIKQERDQLLNEVKTSRN--------ELNSLSEDYE 677

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1175 VEVSKLREISDIAKRQVDFLNSQQQSREKEVESLRTQLLDFQAQSDEKALIAklhqhvVSLQISEATALGKLESVTSKLQ 1254
Cdd:pfam15921  678 VLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVA------MGMQKQITAKRGQIDALQSKIQ 751


                   ...
gi 568967308  1255 KME 1257
Cdd:pfam15921  752 FLE 754
 
Name Accession Description Interval E-value
CEP209_CC5 pfam16574
Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry ...
 1314-1441 5.64e-36

Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry a number of coiled-coil regions, and this is the fifth along the length of the protein. It is thought that the proteins are involved in cilia biosynthesis.


Pssm-ID: 465184 [Multi-domain]  Cd Length: 128  Bit Score: 133.66  E-value: 5.64e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1314 TMIQLQNDKLKIMQEMKNSQQEHRNMENKTLELELKLKGLEELISTLKDARGAQKVINWHVKIEELRLQELKLNRELVKG 1393
Cdd:pfam16574    1 TMIQLQEDKAKLQEELKHAEEERRRAEDRAQELELKLKGLEELISTLKDGKGAQKVTEWHKKMEEIRLQELKLQRELSKQ 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 568967308  1394 KEEIKYLNNIISEYEHTINSLEEEIVQQSKFHEERQMAWDQREVELER 1441
Cdd:pfam16574   81 KEEIKYLENLIREQERTISSLEEEIVQQTKLHEERQLAWDQREVELER 128
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1107-1882 2.57e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.25  E-value: 2.57e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1107 HLRTSLKQMEERNFELETKFTELTKINLDAQKVEQMLRDELADSVTKavsdadRQRILELEKSEVELKVEVSKLREISDI 1186
Cdd:TIGR02168  226 ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEEL------RLEVSELEEEIEELQKELYALANEISR 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1187 AKRQVDFLNSQQQSREKEVESLRTQLLDFQAQSDEKALIAKlhqhvvSLQISEATALGKLESVTSKLQKMEAYNLRLEQK 1266
Cdd:TIGR02168  300 LEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA------ELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1267 LDEKEQALYYARlegrNRAKHLRQTIQSLRrqfsgalplAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEL 1346
Cdd:TIGR02168  374 LEELEEQLETLR----SKVAQLELQIASLN---------NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQA 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1347 ELKLKGLEELISTLKDARGAQKVINWHVKIEELRLQELKLNRELVKGKEEIKYLNNIISEYEHTINSLEEEIVQQSKFHE 1426
Cdd:TIGR02168  441 ELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSG 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1427 ERQMAWDQREV----ELERQLDIFDHQQNEILSAAQKFEDSTGSMPDPSLPLPNQLE---IALRKIKENIQVILKTQATC 1499
Cdd:TIGR02168  521 ILGVLSELISVdegyEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPldsIKGTEIQGNDREILKNIEGF 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1500 KSLEEKLKEKESALRLAEQNILSRDKVINELR--LRLPATADREKLIAELERKELEPKSHHTMKiAHQTIANMQARLNHK 1577
Cdd:TIGR02168  601 LGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDnaLELAKKLRPGYRIVTLDGDLVRPGGVITGG-SAKTNSSILERRREI 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1578 EEVLKKYQHLLEKAREEQREIVkkheedlhvlhhKLEQQADNSLNKFRQTAQDLLKQSPAPVPTNKHFIRLAEMEQTVAE 1657
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALA------------ELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEE 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1658 QDDSLSSLLTKLKKVSKDLEKQKEITELKVREFENTKLRLQEthasEVKKVKAEVEDLRHALAQAHKDSQSLKSELQAQK 1737
Cdd:TIGR02168  748 RIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA----QIEQLKEELKALREALDELRAELTLLNEEAANLR 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1738 E--ANSRAPTTTMRNLVDRLKSQLALKEKQQKALSRALLELRSEMtAAAEERIIAVTSQKEANLNVQQVVERHTRELKSQ 1815
Cdd:TIGR02168  824 ErlESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELI-EELESELEALLNERASLEEALALLRSELEELSEE 902

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568967308  1816 IEDLNENLLKLKEALKTSKNKENSLADDLNELNNELQKKQKAYNK--------ILREKDGIDQENDELRRQIKRL 1882
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEeysltleeAEALENKIEDDEEEARRRLKRL 977
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1648-2365 8.54e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 8.54e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1648 LAEMEQTVAEQDDSLSSLLTKLKKVSKDLEKQKEITEL--------------KVREFENTKLRLQ---ETHASEVKKVKA 1710
Cdd:TIGR02168  188 LDRLEDILNELERQLKSLERQAEKAERYKELKAELRELelallvlrleelreELEELQEELKEAEeelEELTAELQELEE 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1711 EVEDLRHALAQAHKDSQSLKSELQAQKEANSRaptttMRNLVDRLKSQLALKEKQQKALSRALLELRSEMTAAAEERIIA 1790
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQKELYALANEISR-----LEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEL 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1791 VTSQKEANLNVQQVVERHTrELKSQIEDLNENLLKLKEALKTSKNKENSLADDLNELNNELQKKQKAYNKILREKDGIDQ 1870
Cdd:TIGR02168  343 EEKLEELKEELESLEAELE-ELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1871 ENDELRRQIKRLSSGLQSKTLiDNKQSLIDELQKKVKKLESQLERKVDDVDIKPVKEKSSKEEL----IRWEEGKKWQTK 1946
Cdd:TIGR02168  422 EIEELLKKLEEAELKELQAEL-EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELaqlqARLDSLERLQEN 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1947 VEGLRNRLKEKEGEAHGLAKQLNTLKELF----------------------------AKADKEKLTLQKKLKTTGMTVDQ 1998
Cdd:TIGR02168  501 LEGFSEGVKALLKNQSGLSGILGVLSELIsvdegyeaaieaalggrlqavvvenlnaAKKAIAFLKQNELGRVTFLPLDS 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1999 VLGVRALESEKELEELKKKNLDLENDILYMRT------QQALPRDSVVEDL----HLQNKY-LQEKLHTLEKKL------ 2061
Cdd:TIGR02168  581 IKGTEIQGNDREILKNIEGFLGVAKDLVKFDPklrkalSYLLGGVLVVDDLdnalELAKKLrPGYRIVTLDGDLvrpggv 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2062 ----SKEKYSQSLTSEIESDDHCQK-------EQELQKENLKLSSENIELKFQLEQANKDLPRLKNQVKDLKEMCEFLKK 2130
Cdd:TIGR02168  661 itggSAKTNSSILERRREIEELEEKieeleekIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA 740

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2131 GKLELERKLGQ-----VRGAGRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKAsgiltSEKMATIEEENRNLKAELEKL 2205
Cdd:TIGR02168  741 EVEQLEERIAQlskelTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQL-----KEELKALREALDELRAELTLL 815

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2206 KAHFGRQLSMQFESKNKGTEKIVaENERLRKELKKEIEASEKLRIAKNNLELVNDKMAAQLEETGKRLQFAESRAPQLEG 2285
Cdd:TIGR02168  816 NEEAANLRERLESLERRIAATER-RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRS 894

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2286 ADSKSWKSIvvsRVYETKMKELESDIAKKNQSITDLKQLVREAT-EREQKAKKYTEDLEQQIEILKNVPEGAETEQELIR 2364
Cdd:TIGR02168  895 ELEELSEEL---RELESKRSELRRELEELREKLAQLELRLEGLEvRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEAR 971


                   .
gi 568967308  2365 E 2365
Cdd:TIGR02168  972 R 972
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 93-781 8.61e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 8.61e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308    93 KLENELEMAQQSAGGRDTRFLRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENENSKLRRENEQLRQD 172
Cdd:TIGR02168  217 ELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   173 IIDYQKQIDSQKESLlsrrgedSDYRSQLSKKNYELVQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNR 252
Cdd:TIGR02168  297 ISRLEQQKQILRERL-------ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   253 MKALVHQSDAVMDQIKKENEHYRLQVRELtdllkakdeeddpvmmavNAKVEEWKLILSSKDDEIIEYQQMLQSLRGKLK 332
Cdd:TIGR02168  370 LESRLEELEEQLETLRSKVAQLELQIASL------------------NNEIERLEARLERLEDRRERLQQEIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   333 NAQLDADKSNIMALKQGIQERDSQIKMLTEQVEQYTKEMEKNTFIIEDLKNELQKDKG--TSNFYQQTHYMKIHSKVQIL 410
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQArlDSLERLQENLEGFSEGVKAL 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   411 EEKTKEAE----RIAELAEADAR------------------EKDKELVEALKRLKDYESG------VYGLEDAVIEIKNC 462
Cdd:TIGR02168  512 LKNQSGLSgilgVLSELISVDEGyeaaieaalggrlqavvvENLNAAKKAIAFLKQNELGrvtflpLDSIKGTEIQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   463 KAQIKIRD--GEMEVLTKEINKLEMKINDIL-------DENEALRERAGLEPKTMI-----DL----------TEFRNSK 518
Cdd:TIGR02168  592 EILKNIEGflGVAKDLVKFDPKLRKALSYLLggvlvvdDLDNALELAKKLRPGYRIvtldgDLvrpggvitggSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   519 RLKQQQYRAENQVLLKEIES----LEEERLDLKRKIRQMAQE-RGKRNAASGLTIDDLNLSETFSHENKIEGRKLNFMSL 593
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEkiaeLEKALAELRKELEELEEElEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   594 NNMNETQSKNETIVQDLPIQEEQSRNAELELDHQRSQAEQNEF------LSRELAEKEKDLERSRTVIAKFQSKLKELVE 667
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLkeelkaLREALDELRAELTLLNEEAANLRERLESLER 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   668 ENKQLEEGMKEILQAIKDMpkdsdvkggetSLIIPSLERLVNAMESKNAEgifdaslhLKAQVDQLTGRNEELRQELRQS 747
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEEL-----------SEDIESLAAEIEELEELIEE--------LESELEALLNERASLEEALALL 892

                          730       740       750
                   ....*....|....*....|....*....|....
gi 568967308   748 RKEAVNYSQQLVKANLKIDHLEKETDLLRQSAGS 781
Cdd:TIGR02168  893 RSELEELSEELRELESKRSELRRELEELREKLAQ 926
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 327-1209 1.75e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.00  E-value: 1.75e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   327 LRGKLKNAQLDADKSNIMALKQGIQERDSQIKMLTEQVEQYTKEMEKNTFIIEDLKNELQKDKGTSNFYQQTHYmKIHSK 406
Cdd:TIGR02168  218 LKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELY-ALANE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   407 VQILEEKTKEAERIAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVIEIKNCKAQIKirdGEMEVLTKEINKLEMK 486
Cdd:TIGR02168  297 ISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLE---AELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   487 INDILDENEALRERaglepktmidltefRNSKRLKQQQYRAENQVLLKEIESLEEERLDLKRKIRQMAQERGKRNAASgl 566
Cdd:TIGR02168  374 LEELEEQLETLRSK--------------VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKE-- 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   567 tiddlnLSETFSHENKIEgrklnfmslnnmNETQSKNETIVQDLPIQEEQSRNAELELDHQRSQAEQneflsreLAEKEK 646
Cdd:TIGR02168  438 ------LQAELEELEEEL------------EELQEELERLEEALEELREELEEAEQALDAAERELAQ-------LQARLD 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   647 DLERSRTVIAKFQSKLKELVEENKQLEEGMKEILQAIKdmpkdsdVKGGETSLIIPSLERLVNAMESKNAEGIFDASLHL 726
Cdd:TIGR02168  493 SLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELIS-------VDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFL 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   727 KaqvDQLTGRNEELrqELRQSRKEAVNYSQQLVKANLKidhleketdlLRQSAGSNVVYKGIDLPDGIAPSSAYIINSQN 806
Cdd:TIGR02168  566 K---QNELGRVTFL--PLDSIKGTEIQGNDREILKNIE----------GFLGVAKDLVKFDPKLRKALSYLLGGVLVVDD 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   807 eylihlLQELDNKEKKLKHLED--SLEDYnrkfaVIRHQQSLLYKEYLSEKDIWKTDSEM--IREEKRKLEDQAEQDAVK 882
Cdd:TIGR02168  631 ------LDNALELAKKLRPGYRivTLDGD-----LVRPGGVITGGSAKTNSSILERRREIeeLEEKIEELEEKIAELEKA 699

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   883 VKEYNNLLSALQMDSNEMKKMLSENSRKITVLQVNEKSLIRQYTTLVEMERHLRKEngkhRNDVIAMEAEVTEKLGSLQR 962
Cdd:TIGR02168  700 LAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE----LTELEAEIEELEERLEEAEE 775

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   963 FKEMAIFKIAALQKVIDN-----SVSLSELELANKQYNELTTKYRDILQKDNMLVQRTS----NLEHLECENASLKEQME 1033
Cdd:TIGR02168  776 ELAEAEAEIEELEAQIEQlkeelKALREALDELRAELTLLNEEAANLRERLESLERRIAaterRLEDLEEQIEELSEDIE 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1034 AISKELEITKEKLHTIEQAWEQETKLGNDSN--MDKAKKSMTNSdivsiSKKITVLEMKELNERQRAEHCQKMYEHLRTS 1111
Cdd:TIGR02168  856 SLAAEIEELEELIEELESELEALLNERASLEeaLALLRSELEEL-----SEELRELESKRSELRRELEELREKLAQLELR 930

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1112 LKQMEERNFELETKFTELTKINLDAQKVEQMLRDELADSVtkavsdadRQRILELEKSEVEL-KVEVSKLREISDIAKRQ 1190
Cdd:TIGR02168  931 LEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEA--------RRRLKRLENKIKELgPVNLAAIEEYEELKERY 1002

                          890
                   ....*....|....*....
gi 568967308  1191 vDFLNSQQQSREKEVESLR 1209
Cdd:TIGR02168 1003 -DFLTAQKEDLTEAKETLE 1020
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 28-683 2.43e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 66.23  E-value: 2.43e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308    28 LLISLSKVEVNELK------NEDQENMIHLFRITQSLMKMK----AQEVELALEEVEKAGEEQAKFeNQLKTKVMKLENE 97
Cdd:TIGR02168  225 LELALLVLRLEELReeleelQEELKEAEEELEELTAELQELeeklEELRLEVSELEEEIEELQKEL-YALANEISRLEQQ 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308    98 LEMAQQSAGGRDTRFLR--DEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENENSKLRRENEQLRQDIID 175
Cdd:TIGR02168  304 KQILRERLANLERQLEEleAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLET 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   176 YQKQIDSQKESLLSRRGEDSDYRSQLSKKNYELVQYLDEIQTLTEANEKIEVQNQEMR-----KNLEESVQEMEKMTDEY 250
Cdd:TIGR02168  384 LRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAEleeleEELEELQEELERLEEAL 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   251 NRMKALVHQSDAVMDQIKKENEHYRLQVRELTDLLKAKDEEDDPVMMAVNAKV----------------EEWKL------ 308
Cdd:TIGR02168  464 EELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSglsgilgvlselisvdEGYEAaieaal 543

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   309 ------ILSSKDDEIIEYQQML-QSLRGK-----LKNAQLDADKSNIMALKQGIQERDSQIKMLTEQVEQYTKEME---K 373
Cdd:TIGR02168  544 ggrlqaVVVENLNAAKKAIAFLkQNELGRvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSyllG 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   374 NTFIIEDLKNEL----QKDKGTSNFYQQTHYM-----------KIHSKVQILEEKTKEAERIAELAEADAREKDKELVEA 438
Cdd:TIGR02168  624 GVLVVDDLDNALelakKLRPGYRIVTLDGDLVrpggvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   439 LKRLKDYESGVYGL----EDAVIEIKNCKAQIKIRDGEMEVLTKEINKLEMKINDILDENEALRERAGLEPKTMIDLTEF 514
Cdd:TIGR02168  704 RKELEELEEELEQLrkelEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   515 RNSKRLKQQQYRAENQVLLKEIESLEEERLDLKRKIRQMAQERGKRNAASGLTIDDLNLSetfshENKIEGRKLNFMSLN 594
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDL-----EEQIEELSEDIESLA 858

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   595 -NMNETQSKNETIVQDLPIQEEQSRNAELELDHQRSQAEQnefLSRELAEKEKDLERSRTVIAKFQSKLKELVEENKQLE 673
Cdd:TIGR02168  859 aEIEELEELIEELESELEALLNERASLEEALALLRSELEE---LSEELRELESKRSELRRELEELREKLAQLELRLEGLE 935

                          730
                   ....*....|
gi 568967308   674 EGMKEILQAI 683
Cdd:TIGR02168  936 VRIDNLQERL 945
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1670-2025 5.42e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.46  E-value: 5.42e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1670 KKVSKDLEKQKEITELKvREFENTKLRLQETHAsEVKKVKAEVEDLRHALAQAHKDSQSLKSELQAQKEansraptttmr 1749
Cdd:TIGR02168  667 KTNSSILERRREIEELE-EKIEELEEKIAELEK-ALAELRKELEELEEELEQLRKELEELSRQISALRK----------- 733

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1750 nLVDRLKSQLALKEKQQKALSRALLELRSEMTAAAEERIIAvtsqkeanlnvqqvvERHTRELKSQIEDLNENLLKLKEA 1829
Cdd:TIGR02168  734 -DLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEA---------------EEELAEAEAEIEELEAQIEQLKEE 797

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1830 LKTSKNKENSLADDLNELNNELQKKQKAYNKILREKDGIDQENDELRRQIKRLSSGLQSKTLidnkqsLIDELQKKVKKL 1909
Cdd:TIGR02168  798 LKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAA------EIEELEELIEEL 871

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1910 ESQLERKVDDVDIKPVKEKSSKEELIrweegkKWQTKVEGLRNRLKEKEGEAHGLAKQLNTLKELFAKADKEKLTLQKKL 1989
Cdd:TIGR02168  872 ESELEALLNERASLEEALALLRSELE------ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 568967308  1990 KTTGMTVDQVLGVRALESEKELEELKKKNLDLENDI 2025
Cdd:TIGR02168  946 SEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1658-1939 5.33e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 5.33e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1658 QDDSLSSLLTKLKKVSKDLEKQKEITELKVREFENTKLRLQETHASEVKKVKAEVEDLRHALAQAHKDSQSLKSELQAQK 1737
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1738 EANSRAptttmrnlvDRLKSQLALKEKQQKALSRALLELRSEMTAAAEERIIAvtsqKEANLNVQQVVERHTRELKSQIE 1817
Cdd:COG1196   313 ELEERL---------EELEEELAELEEELEELEEELEELEEELEEAEEELEEA----EAELAEAEEALLEAEAELAEAEE 379

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1818 DLNENLLKLKEALKTSKNKENSLADDLNELNNELQKKQKAYNKILREKDGIDQENDELRRQIKRLSSGLQSKTLIDNKQS 1897
Cdd:COG1196   380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 568967308 1898 LIDELQKKVKKLESQLERKVDDVDIKPVKEKSSKEELIRWEE 1939
Cdd:COG1196   460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEA 501
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1582-2453 6.69e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.61  E-value: 6.69e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1582 KKYQHLLEKAREEQREIVKKHEEDLHVLHHKLEQQAdNSLNKFRQTAQDLLKQSPAPVPTNKHFIRlaEMEQTVAEQDDS 1661
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEELREELEELQEEL-KEAEEELEELTAELQELEEKLEELRLEVS--ELEEEIEELQKE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1662 LSSLLTKLKkvskDLEKQKEITELKVREFENTKLRLQEthasEVKKVKAEVEDLRHALAQAHKDSQSLKSELQAQKEANS 1741
Cdd:TIGR02168  290 LYALANEIS----RLEQQKQILRERLANLERQLEELEA----QLEELESKLDELAEELAELEEKLEELKEELESLEAELE 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1742 RAptttmRNLVDRLKSQLALKEKQQKALSRALLELRSEMTAAAEERIIAVTSQKEANLNVQQvverhtreLKSQIEDLNE 1821
Cdd:TIGR02168  362 EL-----EAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRER--------LQQEIEELLK 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1822 NLLKLKeaLKTSKNKENSLADDLNELNNELQKKQKAYNKILREKDGIDQENDELRRQIKRLSSGLQSKTLIDNKQSLIDE 1901
Cdd:TIGR02168  429 KLEEAE--LKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSE 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1902 LQKKVKKLESQLERKVDDVdikpvkeksskEELIRWEEGkkWQTKVE-GLRNRL-------KEKEGEAHGLAKQLNTLKE 1973
Cdd:TIGR02168  507 GVKALLKNQSGLSGILGVL-----------SELISVDEG--YEAAIEaALGGRLqavvvenLNAAKKAIAFLKQNELGRV 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1974 LFAKADKEKLT-LQKKLKTTGMTVDQVLGVralesekeLEELKKKNLDLENDILYMrTQQALPRDSVVEDLHLQNKY-LQ 2051
Cdd:TIGR02168  574 TFLPLDSIKGTeIQGNDREILKNIEGFLGV--------AKDLVKFDPKLRKALSYL-LGGVLVVDDLDNALELAKKLrPG 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2052 EKLHTLEKKLSKEKYSQSLTSEIESddhcQKEQELQKENLKLSSENIELKFQLEQANKDLPRLKNQVKDLKEMCEFLKKG 2131
Cdd:TIGR02168  645 YRIVTLDGDLVRPGGVITGGSAKTN----SSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKE 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2132 KLELERKLGQVR-GAGRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKASGILTSEKmATIEEENRNLKAELEKLKahfg 2210
Cdd:TIGR02168  721 LEELSRQISALRkDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL-AEAEAEIEELEAQIEQLK---- 795

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2211 rqlsmqfESKNKGTEKIVAENERLRKelkkeieasekLRIAKNNLELVNDKMAAQLEETGKRLQFAESRAPQLEGADSKs 2290
Cdd:TIGR02168  796 -------EELKALREALDELRAELTL-----------LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES- 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2291 wksivvsrvYETKMKELESDIAKKNQSITDLKQLVREATEREQKAKKYTEDLEQQIEilknvpEGAETEQELIRELQLLR 2370
Cdd:TIGR02168  857 ---------LAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELR------ELESKRSELRRELEELR 921

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2371 LANNQMDKERAELIHQIEINKDQTRADSSIPdsdqlkekINDLETQLRKLELEKQHSKEEVKKLKKELENFDPSFFEEIE 2450
Cdd:TIGR02168  922 EKLAQLELRLEGLEVRIDNLQERLSEEYSLT--------LEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIE 993


                   ...
gi 568967308  2451 DLK 2453
Cdd:TIGR02168  994 EYE 996
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 113-686 8.13e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.49  E-value: 8.13e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  113 LRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENENSKLRRENEQLRQDIIDYQKQIDSQKESLLSRRG 192
Cdd:COG1196   244 LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEE 323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  193 EDSDYRSQLSKKNYELVQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKALVHQSDAVMDQIKKENE 272
Cdd:COG1196   324 ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  273 HYRLQVRELTDLLKAKDEEddpvmmavnakVEEWKLILSSKDDEIIEYQQMLQSLRGKLKNAQLDAdKSNIMALKQGIQE 352
Cdd:COG1196   404 ELEEAEEALLERLERLEEE-----------LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE-EALLELLAELLEE 471

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  353 RDSQIKMLTEQVEQYTKEMEKNTFIIEDLKNELQKDKGTSNFYQQTHYMKIHSKVQILEEKTKEAERIAELAEADA---- 428
Cdd:COG1196   472 AALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAAlqni 551

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  429 -REKDKELVEALKRLKDYESG-------------------------VYGLEDAVIEIKNCKAQIKIRDGEMEVLTKEINK 482
Cdd:COG1196   552 vVEDDEVAAAAIEYLKAAKAGratflpldkiraraalaaalargaiGAAVDLVASDLREADARYYVLGDTLLGRTLVAAR 631

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  483 LEMKINDILDENEALRERAGLEPKTMIDLTEFRNSKRLKQQQYRAENQVLLKEIESLEEERLDLKRKIRQMAQERGKRNA 562
Cdd:COG1196   632 LEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAE 711

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  563 ASGLTIDDLNLSEtfshenkiegrklnfmslnnmNETQSKNETIVQDLPIQEEQSRNAELELDHQRSQAEQNEFLSRELA 642
Cdd:COG1196   712 AEEERLEEELEEE---------------------ALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568967308  643 EKEKDLERSRTV----IAKFQS---KLKELVEENKQLEEGMKEILQAIKDM 686
Cdd:COG1196   771 RLEREIEALGPVnllaIEEYEEleeRYDFLSEQREDLEEARETLEEAIEEI 821
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 114-493 1.41e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.46  E-value: 1.41e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   114 RDEIRQLEKQLEQKDRELEDMEKELdkekkvneqlalrnEEAENENSKLRRENEQLRQDIIDYQKQIDSQKESLLSRRGE 193
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKAL--------------AELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAE 741

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   194 DSDYRSQLSKKNYELVQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEynrMKALVHQSDAVMDQIKKENEH 273
Cdd:TIGR02168  742 VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEE---LKALREALDELRAELTLLNEE 818

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   274 YRLQVRELTDLLKAKDEEDDPVMMAVNAKVEEwKLILSSKDDEIIEYQQMLQSLRGKLKNA--QLDADKSNIMALKQGIQ 351
Cdd:TIGR02168  819 AANLRERLESLERRIAATERRLEDLEEQIEEL-SEDIESLAAEIEELEELIEELESELEALlnERASLEEALALLRSELE 897

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   352 ERDSQIKMLTEQVEQYTKEMEKNTFIIEDLKNELQKDKGTSNFYQQthymKIHSKVQILEEKTKEAERIAELAEADAREK 431
Cdd:TIGR02168  898 ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQE----RLSEEYSLTLEEAEALENKIEDDEEEARRR 973

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568967308   432 DKELVEALKRLkdyesGVYGLeDAVIEIKNCKAQIKIRDGEMEVLTKEINKLEMKINDILDE 493
Cdd:TIGR02168  974 LKRLENKIKEL-----GPVNL-AAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 114-452 2.53e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 59.70  E-value: 2.53e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   114 RDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQL----ALRNEEAENENSKLRRENEQLRQDIIDYQKQIDSQKESLLS 189
Cdd:TIGR02169  176 LEELEEVEENIERLDLIIDEKRQQLERLRREREKAeryqALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEK 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   190 RRGEDSDYRSQLSKKNYELVQYLDEIQTLTEAN--------EKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKALVHQSD 261
Cdd:TIGR02169  256 LTEEISELEKRLEEIEQLLEELNKKIKDLGEEEqlrvkekiGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   262 AVMDQIKKENEHYRLQVRELTDLLKA-KDEEDDPV--MMAVNAKVEEWKLILSSKDDEIIEYQQMLQSLRGKLKNAQLDA 338
Cdd:TIGR02169  336 AEIEELEREIEEERKRRDKLTEEYAElKEELEDLRaeLEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEEL 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   339 DK--SNIMALKQGIQERDSQIKMLTEQVEQYTKEMEKNTFIIEDLKNELQKdkgtsnfYQQTHYmKIHSKVQILEEKTKE 416
Cdd:TIGR02169  416 QRlsEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSK-------YEQELY-DLKEEYDRVEKELSK 487

                          330       340       350
                   ....*....|....*....|....*....|....*....
gi 568967308   417 AERIAELAEADAR---EKDKELVEALKRLKDYESGVYGL 452
Cdd:TIGR02169  488 LQRELAEAEAQARaseERVRGGRAVEEVLKASIQGVHGT 526
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 518-1300 2.98e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.69  E-value: 2.98e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   518 KRLKQQQYRAENQVLLKEIESLEEERLDLKRKIRQMAQERGKRNAASGLTIDDLNLSETFSHENKIEGRKLNfMSLNNMN 597
Cdd:TIGR02168  216 KELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQ-KELYALA 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   598 ETQSKNETIVQDLPIQEEQSRNAELELDHQRSQAEQ-NEFLSRELAEKEKDLERSRTVIAKFQSKLKELVEENKQLEEGM 676
Cdd:TIGR02168  295 NEISRLEQQKQILRERLANLERQLEELEAQLEELESkLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   677 KEILQAIKDMPKDSDVKGGETSLIIPSLERLvnamesknaegifdaslhlKAQVDQLTGRNEELRQELRQSRKEAVNYSQ 756
Cdd:TIGR02168  375 EELEEQLETLRSKVAQLELQIASLNNEIERL-------------------EARLERLEDRRERLQQEIEELLKKLEEAEL 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   757 QLVKANLKIDHLEKETDLLRQSAGsnvvykgidlpdgiapssayiinsqNEYLIHLLQELDNKEKKLKHLEDSLEDYNRK 836
Cdd:TIGR02168  436 KELQAELEELEEELEELQEELERL-------------------------EEALEELREELEEAEQALDAAERELAQLQAR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   837 FAVIRHQQSLLYKEYLSEKDIWKTdsemirEEKRKLEDQAEQDAVKV-KEYNNLLSALQMDSNEMKKMLSENSRKITVLQ 915
Cdd:TIGR02168  491 LDSLERLQENLEGFSEGVKALLKN------QSGLSGILGVLSELISVdEGYEAAIEAALGGRLQAVVVENLNAAKKAIAF 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   916 VNEKSLIRQyTTLVEMERHLRKENGKHRNdviaMEAEVTEKLGSLQRFKEMAIFKIAALQKVIDNSVSLSELELANKQYN 995
Cdd:TIGR02168  565 LKQNELGRV-TFLPLDSIKGTEIQGNDRE----ILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAK 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   996 ELTTKYRDI-----------------LQKDNMLVQRTSNLEHLECENASLKEQMEAISKELEITKEKLHTIEQAWEQETK 1058
Cdd:TIGR02168  640 KLRPGYRIVtldgdlvrpggvitggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRK 719

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1059 LGNDsnmdkakksmtnsdivsISKKITVLEMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELETKFTELTKiNLDAQK 1138
Cdd:TIGR02168  720 ELEE-----------------LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE-ELAEAE 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1139 VEQMLRDELADSVTKAVSdADRQRILELEKSEVELKVEVSKLREISDIAKRQVDFLNSQQQSREKEVESLRTQLLDFQAQ 1218
Cdd:TIGR02168  782 AEIEELEAQIEQLKEELK-ALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE 860

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1219 -SDEKALIAKLHQHVVSLQISEATALGKLESVTSKLQKMEAYNLRLEQKLDEKEQALYYARL---EGRNRAKHLRQTIQS 1294
Cdd:TIGR02168  861 iEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREklaQLELRLEGLEVRIDN 940


                   ....*.
gi 568967308  1295 LRRQFS 1300
Cdd:TIGR02168  941 LQERLS 946
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 113-712 3.06e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.57  E-value: 3.06e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  113 LRDEIRQLEKQLEQKDRELEDMEK--ELDKEKKV--NEQLALRNEEAENENSKLRRENEQLRQDIIDYQKQIDSQKESLL 188
Cdd:COG1196   191 LEDILGELERQLEPLERQAEKAERyrELKEELKEleAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELE 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  189 SRRGEDSDYRSQLSKKNYELVQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKALVHQSDAVMDQIK 268
Cdd:COG1196   271 ELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE 350

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  269 KENEHYRLQVRELTDLLKAKDEEDDPVMMAVNAKVEEwkliLSSKDDEIIEYQQMLQSLRGKLKNAQLDADksnimALKQ 348
Cdd:COG1196   351 EELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE----LLEALRAAAELAAQLEELEEAEEALLERLE-----RLEE 421

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  349 GIQERDSQIKMLTEQVEQYTKEMEKNTFIIEDLKNELQKDKgtsnfyqqthymKIHSKVQILEEKTKEAERIAELAEADA 428
Cdd:COG1196   422 ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALL------------ELLAELLEEAALLEAALAELLEELAEA 489

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  429 REKDKELVEALKRLKDYESGVYGLEDAVIEIKNCKAQIKIRDGEMEVLTKEINKLEMKINDILDENEALRERAGLEPK-- 506
Cdd:COG1196   490 AARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKaa 569

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  507 -----TMIDLTEFRNSKRLKQQQYRAENQVLLKEIESLEEERLDLKRKIRQMAQERGKRNAASGLTIDDLNLSETFSHEN 581
Cdd:COG1196   570 kagraTFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREV 649

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  582 KIEGRKLNFMSLNNMNETQSKNETIVQDLPIQEEQSRNAELELDHQRSQAEQNEFLSRELAEKEKDLERSRTVIAKFQSK 661
Cdd:COG1196   650 TLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQ 729

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568967308  662 LKELVEENKQLEEGMKEILQAIKDMPKDSDVKGGETSLIIPSLERLVNAME 712
Cdd:COG1196   730 LEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1810-2476 6.86e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.53  E-value: 6.86e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1810 RELKSQIEDLNENLLKLKEALKTSKNKENSL------ADDLNELNNELQKKQKAYnkILREKDGIDQENDELRRQIKRLS 1883
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQLKSLerqaekAERYKELKAELRELELAL--LVLRLEELREELEELQEELKEAE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1884 SGLQS-KTLIDNKQSLIDELQKKVKKLESQLERKVDDVDIKpVKEKSSKEELIRweegkKWQTKVEGLRNRLKEKEGEAH 1962
Cdd:TIGR02168  253 EELEElTAELQELEEKLEELRLEVSELEEEIEELQKELYAL-ANEISRLEQQKQ-----ILRERLANLERQLEELEAQLE 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1963 GLAKQLNTLKELFAKADKEKLTLQKKLKTtgmtvdqvLGVRALESEKELEELKKKNLDLENDILYMRTQQALPRDSVvED 2042
Cdd:TIGR02168  327 ELESKLDELAEELAELEEKLEELKEELES--------LEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI-AS 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2043 LHLQNKYLQEKLHTLEKKLSKEKYSQSL----TSEIESDDHCQKEQELQKENLKLSSENIELKFQLEQANKDLPRLKNQV 2118
Cdd:TIGR02168  398 LNNEIERLEARLERLEDRRERLQQEIEEllkkLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQAL 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2119 KDLKEMCEFLKKGKLELERKLGQVRGAGRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKASGILTSEKMATIEEENRN- 2197
Cdd:TIGR02168  478 DAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNa 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2198 LKAELEKLKAHFGRQLSMQFESKNKGTEKIVAENERLRKE------LKKEIEASEKLRIAKNNLeLVNDKMAAQLE---E 2268
Cdd:TIGR02168  558 AKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIegflgvAKDLVKFDPKLRKALSYL-LGGVLVVDDLDnalE 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2269 TGKRLQFAE----------SRAPQLEGADSKSWKSIVVSRV----YETKMKELESDIAKKNQSITDLKQLVREATEREQK 2334
Cdd:TIGR02168  637 LAKKLRPGYrivtldgdlvRPGGVITGGSAKTNSSILERRReieeLEEKIEELEEKIAELEKALAELRKELEELEEELEQ 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2335 AKKYTEDLEQQIEILKNVPEGAETEQELIRE-LQLLRLANNQMDKERAELIHQIEINKDQTRADSSipDSDQLKEKINDL 2413
Cdd:TIGR02168  717 LRKELEELSRQISALRKDLARLEAEVEQLEErIAQLSKELTELEAEIEELEERLEEAEEELAEAEA--EIEELEAQIEQL 794

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568967308  2414 ETQLRKL-----ELEKQHSKEEVKKLKKElenfdpsffEEIEDLKYNYKEEVKKNILLEEKLKKLSEQ 2476
Cdd:TIGR02168  795 KEELKALrealdELRAELTLLNEEAANLR---------ERLESLERRIAATERRLEDLEEQIEELSED 853
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 109-365 3.07e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 56.23  E-value: 3.07e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   109 DTRFLRDEIRQLEKQLEQKDRELEDMEKELDK-EKKVNEQLALRNE------EAENENSKLRRENEQLRQDIIDYQKQID 181
Cdd:TIGR02169  668 FSRSEPAELQRLRERLEGLKRELSSLQSELRRiENRLDELSQELSDasrkigEIEKEIEQLEQEEEKLKERLEELEEDLS 747

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   182 SQKESLLSRRGEDSDYRSQLSKKNYELVQYLDEIQTL--TEANEKIEVQNQEMRKnLEESVQEMEKMTDEYNRMKALVHQ 259
Cdd:TIGR02169  748 SLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLeaRLSHSRIPEIQAELSK-LEEEVSRIEARLREIEQKLNRLTL 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   260 SDAVMDQIKKENEHYRLQVRELTDLLKAKDEEDdpvmmavNAKVEEWKLILSSKDDEIIEYQQMLQSLRGKLKN--AQLD 337
Cdd:TIGR02169  827 EKEYLEKEIQELQEQRIDLKEQIKSIEKEIENL-------NGKKEELEEELEELEAALRDLESRLGDLKKERDEleAQLR 899

                          250       260
                   ....*....|....*....|....*...
gi 568967308   338 ADKSNIMALKQGIQERDSQIKMLTEQVE 365
Cdd:TIGR02169  900 ELERKIEELEAQIEKKRKRLSELKAKLE 927
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 230-999 4.69e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.45  E-value: 4.69e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   230 QEMRKNLEESVQEMEKMTD---EYNR-MKALVHQSDAVMDQIKKENEHYRLQVRELTDLLKAKDEEDDPVMMAVNAKVEE 305
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDilnELERqLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   306 wkliLSSKDDEIIEYQQMLQSLRGKL--KNAQLDADKSNIMALKQGIQERDSQIKMLTEQVEQYTKEMEKNTFIIEDLKN 383
Cdd:TIGR02168  255 ----LEELTAELQELEEKLEELRLEVseLEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   384 ELQKDKgtsnfyqqthymkihSKVQILEEKTKEAERIAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVIEIKNCK 463
Cdd:TIGR02168  331 KLDELA---------------EELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   464 AQIKirdGEMEVLTKEINKLEMKINDILDENEALRERagLEPKTMIDLTEFRNSKRLKQQQYRAENQVLLKEIESLEEER 543
Cdd:TIGR02168  396 ASLN---NEIERLEARLERLEDRRERLQQEIEELLKK--LEEAELKELQAELEELEEELEELQEELERLEEALEELREEL 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   544 LDLKRKIRQMAQERGKRNAASGLTIDDLNLSETFSHENKI-----EGRKLNFMSLNNMNETQSKNET--------IVQDL 610
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKAllknqSGLSGILGVLSELISVDEGYEAaieaalggRLQAV 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   611 PIQEEQSRNAELELDHQRSQAEQNEFL--SRELAEKEKDLERSRTVIAKFQSKLKELVEENKQLEEGMKEIL-------- 680
Cdd:TIGR02168  551 VVENLNAAKKAIAFLKQNELGRVTFLPldSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLggvlvvdd 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   681 --QAIKDMPKdsdvKGGETSLIIPSLERL-----VNAMESKNAEGIFD---ASLHLKAQVDQLTGRNEELRQELRQSRKE 750
Cdd:TIGR02168  631 ldNALELAKK----LRPGYRIVTLDGDLVrpggvITGGSAKTNSSILErrrEIEELEEKIEELEEKIAELEKALAELRKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   751 AVNYSQQLVKANLKIDHLEKETDLLRQSAG-----SNVVYKGIDLPDGIAPSSAYIINSQNEYLIHLLQELDNKEKKLKH 825
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLArleaeVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   826 LEDSLEDYNRKFAVIRHQQSLLYKEY----------LSEKDIWKTDSEMIREEKRKLEDQAEQDAVKVKEYNNLLSALQM 895
Cdd:TIGR02168  787 LEAQIEQLKEELKALREALDELRAELtllneeaanlRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   896 DSNEMKKMLSENSRKITVLQVNEKSLIRQYTTLVEMERHLRKENGKHRNDVIameaEVTEKLGSLQRFKEMAIFKIAALQ 975
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELE----ELREKLAQLELRLEGLEVRIDNLQ 942

                          810       820
                   ....*....|....*....|....
gi 568967308   976 KVIDNSVSLsELELANKQYNELTT 999
Cdd:TIGR02168  943 ERLSEEYSL-TLEEAEALENKIED 965
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 75-459 7.21e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.06  E-value: 7.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308    75 KAGEEQAKFENQLKTKVMKLENELEMAQQsaggrDTRFLRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEE 154
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEELEE-----ELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   155 AENENSKLRRENEQLRQDIIDYQKQIDSQKESLLSRRGEDSDYRSQLSKKNYELVQYLDEIQTLTEANEKIEVQNQEMRK 234
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATER 838

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   235 NLEESVQEMEKMTDEynrmkalvhqsdavMDQIKKENEHYRLQVRELTDLLKAKDEEddpvMMAVNAKVEEWKLILSSKD 314
Cdd:TIGR02168  839 RLEDLEEQIEELSED--------------IESLAAEIEELEELIEELESELEALLNE----RASLEEALALLRSELEELS 900

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   315 DEIIEYQQMLQSLRGKLKNAQLDADKSNiMALKQGIQERDSQIKMLTEQVEQYTKEMEKNTFIIEDLKNELQKdkgtsnf 394
Cdd:TIGR02168  901 EELRELESKRSELRRELEELREKLAQLE-LRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARR------- 972

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568967308   395 yqqthymkihsKVQILEEKTKEAERIAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVIEI 459
Cdd:TIGR02168  973 -----------RLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEI 1026
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1666-2426 8.32e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 54.68  E-value: 8.32e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1666 LTKLKKVSKDLEKQKEitelkvrefentKLRLQETHASEVKKVKAEVEDLRHALAQAHKdsQSLKSELQAQKEAnsrapt 1745
Cdd:TIGR02168  188 LDRLEDILNELERQLK------------SLERQAEKAERYKELKAELRELELALLVLRL--EELREELEELQEE------ 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1746 ttmrnlVDRLKSQLALKEKQQKALSRALLELRSEMTAAAEERIIAVTSQKEANlNVQQVVERHTRELKSQIEDLNENLLK 1825
Cdd:TIGR02168  248 ------LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA-NEISRLEQQKQILRERLANLERQLEE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1826 LKEALKTSKNKENSLADDLNELNNELQKKQKaynkilrEKDGIDQENDELRRQIKRLSSGLQSK-TLIDNKQSLIDELQK 1904
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAELEEKLEELKE-------ELESLEAELEELEAELEELESRLEELeEQLETLRSKVAQLEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1905 KVKKLESQLERKVDDVDIKPVKEKSSKEElIRWEEGKKWQTKVEGLRNRLKEKEGEAHGLAKQLNTLKELFAKADKEKLT 1984
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQE-IEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEE 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1985 LQKKLKTTGMTVDQvLGVRALESEKELEELKKKNLDLENdILYMRTQQALPRDSVVEDLHLQNKYLQEKLHTLEKKLske 2064
Cdd:TIGR02168  473 AEQALDAAERELAQ-LQARLDSLERLQENLEGFSEGVKA-LLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRL--- 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2065 kysQSLTseIESDDHCQKEQELQKENLKLSSENIELkfqleqankdlprlknqvkDLKEMCEFLKKGKLELERKLGQVRG 2144
Cdd:TIGR02168  548 ---QAVV--VENLNAAKKAIAFLKQNELGRVTFLPL-------------------DSIKGTEIQGNDREILKNIEGFLGV 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2145 AGRSGKTIPELEKTIGLM---KKVVEKVQRENEQLKKasgiltsekmatIEEENRNLKAELEKLKAHFgrQLSMQFESKN 2221
Cdd:TIGR02168  604 AKDLVKFDPKLRKALSYLlggVLVVDDLDNALELAKK------------LRPGYRIVTLDGDLVRPGG--VITGGSAKTN 669

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2222 KGTEKIVAENERLRKELKkeiEASEKLRIAKNNLELVNDKMAAQLEETGKRLQFAESRAPQLEGADSKSWKSIVVSRVYE 2301
Cdd:TIGR02168  670 SSILERRREIEELEEKIE---ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2302 TKMKELESDIAKKNQSITDLKQLVREATEREQKAKKYTEDLEQQIEILKNVPEGAETE--------QELIRELQLLRLAN 2373
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREAldelraelTLLNEEAANLRERL 826

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|...
gi 568967308  2374 NQMDKERAELIHQIEINKDQTRADSSipDSDQLKEKINDLETQLRKLELEKQH 2426
Cdd:TIGR02168  827 ESLERRIAATERRLEDLEEQIEELSE--DIESLAAEIEELEELIEELESELEA 877
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1504-2273 8.98e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 54.68  E-value: 8.98e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1504 EKLKEKESALRLAEQNILSRDKVINELRLRLPaTADREKLIAELERKELEPKSHHTMKIAHQTIANMQARLNHKEEVLKK 1583
Cdd:TIGR02168  172 ERRKETERKLERTRENLDRLEDILNELERQLK-SLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1584 YQHLLEKAREEQREIVKKHEEdLHVLHHKLEQQAdnslnkfrQTAQDLLKQspapvptnkHFIRLAEMEQTVAEQDDSLS 1663
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEE-LRLEVSELEEEI--------EELQKELYA---------LANEISRLEQQKQILRERLA 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1664 SLLTKLKKVSKDLEKQKEITELKVREFENTKLRLQEthasevkkVKAEVEDLRHALAQAHKDSQSLKSELQAQKEAnsra 1743
Cdd:TIGR02168  313 NLERQLEELEAQLEELESKLDELAEELAELEEKLEE--------LKEELESLEAELEELEAELEELESRLEELEEQ---- 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1744 ptttmrnlVDRLKSQLALKEKQQKALSRALLELRSEMTAAAE--ERIIAVTSQKEANLNVQQVVERHTR---------EL 1812
Cdd:TIGR02168  381 --------LETLRSKVAQLELQIASLNNEIERLEARLERLEDrrERLQQEIEELLKKLEEAELKELQAEleeleeeleEL 452

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1813 KSQIEDLNENLLKLKEALKTSKNKENSLADDLNELNNE---LQKKQKAYNKILREKDGIDQENDELRRQIKRLSSGLQ-- 1887
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQALDAAERELAQLQARldsLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISvd 532

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1888 -------SKTLIDNKQSLIDELQKKVKK-LESQLERKVDDVDIKPVKEKSSKEELIRWEEGKKWQTKVEGLRNRLKEKEG 1959
Cdd:TIGR02168  533 egyeaaiEAALGGRLQAVVVENLNAAKKaIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDP 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1960 EAHG--------------LAKQLNTLKEL-----------------------FAKADKEKLTLQKKLKTTGMTVDQvLGV 2002
Cdd:TIGR02168  613 KLRKalsyllggvlvvddLDNALELAKKLrpgyrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEKIEE-LEE 691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2003 RALESEKELEELKKKNLDLENDilymrtqqalprdsvVEDLHLQNKYLQEKLHTLEKKLSK-EKYSQSLTSEIESDDHCQ 2081
Cdd:TIGR02168  692 KIAELEKALAELRKELEELEEE---------------LEQLRKELEELSRQISALRKDLARlEAEVEQLEERIAQLSKEL 756

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2082 KEQELQKEnlKLSSENIELKFQLEQANKDLPRLKNQVKDLKEMCEFLKKGKLELERKLGQVRG-AGRSGKTIPELEKTIG 2160
Cdd:TIGR02168  757 TELEAEIE--ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEeAANLRERLESLERRIA 834

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2161 LMKKVVEKVQRENEQLKKASGILTSEkMATIEEENRNLKAELEKLKAHFgRQLSMQFESKNKGTEKIVAENERLRKELKK 2240
Cdd:TIGR02168  835 ATERRLEDLEEQIEELSEDIESLAAE-IEELEELIEELESELEALLNER-ASLEEALALLRSELEELSEELRELESKRSE 912

                          810       820       830
                   ....*....|....*....|....*....|...
gi 568967308  2241 EIEASEKLRIAKNNLELVNDKMAAQLEETGKRL 2273
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
PTZ00121 PTZ00121
MAEBL; Provisional
 1763-2411 1.27e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 54.38  E-value: 1.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1763 EKQQKALSRALLELRSEMTAAAEERIIAVTSQKEANLNVQQvvERHTRELKSQIEDLNENLLKLKEALKTS-----KNKE 1837
Cdd:PTZ00121 1236 KKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEE--ARKADELKKAEEKKKADEAKKAEEKKKAdeakkKAEE 1313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1838 NSLADDLNELNNELQKKQKAYNKILREKDGIDQENDELRRQIKRLSSGLQSKTLIDNKQSliDELQKKVKKLESQLE--R 1915
Cdd:PTZ00121 1314 AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKK--EEAKKKADAAKKKAEekK 1391

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1916 KVDDVDIKPVKEKSSKEELIRWEEGKKwqtkveglrnrlkeKEGEAHGLAKQLNTLKELFAKADKEKLTLQKKLKTTGMT 1995
Cdd:PTZ00121 1392 KADEAKKKAEEDKKKADELKKAAAAKK--------------KADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAK 1457

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1996 VDQVLGVRALESEKELEELKKKNLDLENDILYMRTQQALPRDSVVEDLHLQNKYLQEKLHTLEKKLSKE---KYSQSLTS 2072
Cdd:PTZ00121 1458 KAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEakkAEEAKKAD 1537

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2073 EIESDDHCQKEQELQK-ENLKLSSE--NIELKFQLEQANKDLPRLKNQVKDLKE--MCEFLKKGKLELERKLGQVRGAGR 2147
Cdd:PTZ00121 1538 EAKKAEEKKKADELKKaEELKKAEEkkKAEEAKKAEEDKNMALRKAEEAKKAEEarIEEVMKLYEEEKKMKAEEAKKAEE 1617

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2148 SGKTIPELEKTIGLMKKVVEKVQRENEQLKKASGILTSEKMATIEEENRNLKAELEKLKAhfgRQLSMQFESKNKGTEKI 2227
Cdd:PTZ00121 1618 AKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKA---EEAKKAEEDEKKAAEAL 1694

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2228 VAENERLRK-ELKKEIEASEKlriaknnlelvndKMAAQLEETGKRLQFAESRAPQLEGADSKSWKSIVVSRVYETKMKE 2306
Cdd:PTZ00121 1695 KKEAEEAKKaEELKKKEAEEK-------------KKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAH 1761

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2307 LESDIAKKNQSITDLKQLV------REATEREQKAKKYTEDLEQQIEIL-----KNVPEGAETEQELIRELQLLRLANNq 2375
Cdd:PTZ00121 1762 LKKEEEKKAEEIRKEKEAVieeeldEEDEKRRMEVDKKIKDIFDNFANIieggkEGNLVINDSKEMEDSAIKEVADSKN- 1840

                         650       660       670
                  ....*....|....*....|....*....|....*.
gi 568967308 2376 MDKERAELIHQIEINKDQTRADSSIPDSDQLKEKIN 2411
Cdd:PTZ00121 1841 MQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDL 1876
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
54-187 1.67e-06

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 53.32  E-value: 1.67e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   54 ITQSLMKMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLENELEMaqqsaggrdtrfLRDEIRQLEKQLEQKDRELED 133
Cdd:COG2433   378 IEEALEELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVER------------LEAEVEELEAELEEKDERIER 445

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 568967308  134 MEKELDKEKKVNEQLALRNEEAenenSKLRRENEQLRQDIIDYQKQIDSQKESL 187
Cdd:COG2433   446 LERELSEARSEERREIRKDREI----SRLDREIERLERELEEERERIEELKRKL 495
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1375-1915 2.01e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 2.01e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1375 KIEELRLQELKLNRELVKGKEEIKYLNNIISEYEHTINSLEEEIVQQSKFHEERQMAWDQREVELERQLDIFDHQQNEIL 1454
Cdd:COG1196   268 ELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELE 347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1455 SAAQKFEDSTGSMpdpslplpNQLEIALRKIKENIQVILKTQATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRL 1534
Cdd:COG1196   348 EAEEELEEAEAEL--------AEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL 419

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1535 PATADREKLIAELERKELEPKSHHTMKIAHQTIANMQARLNHKEEVLKKYQhlLEKAREEQREIVKKHEEDLHVLHHKLE 1614
Cdd:COG1196   420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLE--EAALLEAALAELLEELAEAAARLLLLL 497

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1615 QQADNSLNKFRQTAQDLLKQSPAPVPtnKHFIRLAEMEQTVAEQDDSLSSLLTKLKKVSKDLEKQKEITELKvrefENTK 1694
Cdd:COG1196   498 EAEADYEGFLEGVKAALLLAGLRGLA--GAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLK----AAKA 571

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1695 LRLQETHASEVKKVKAEVEDlrHALAQAHKDSQSLKSELQAQKEANSRAPTTTMRNLVDRLKSQLALKEKqqKALSRALL 1774
Cdd:COG1196   572 GRATFLPLDKIRARAALAAA--LARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRA--VTLAGRLR 647

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1775 ELRSEMTAAAEERIIAVTSQKEANLNVQQVVERHTRELKSQIEDLNENLLKLKEALKTSKNKENSLADDLNELNNELQKK 1854
Cdd:COG1196   648 EVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALE 727

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568967308 1855 QKAYNKILREKDGIDQENDELRRQIKRLSSGLQSktlidnkqslIDELQKKVKKLESQLER 1915
Cdd:COG1196   728 EQLEAEREELLEELLEEEELLEEEALEELPEPPD----------LEELERELERLEREIEA 778
PRK11281 PRK11281
mechanosensitive channel MscK;
1660-1912 2.24e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 53.38  E-value: 2.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1660 DSLSSLLTKLKKvSKDLEKQKEITelkVREFENTKLRLQEThasevKKVKAEVEDLRHALAQAHKDSQSLKSELQAQKEA 1739
Cdd:PRK11281   39 ADVQAQLDALNK-QKLLEAEDKLV---QQDLEQTLALLDKI-----DRQKEETEQLKQQLAQAPAKLRQAQAELEALKDD 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1740 NSRAPTTTMRNL-VDRLKSQLALKEKQQKALSRALLELRSEMTAA--AEERiiavtSQKEANLNVQQvverhTRELKSQI 1816
Cdd:PRK11281  110 NDEETRETLSTLsLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLqtQPER-----AQAALYANSQR-----LQQIRNLL 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1817 EDLNENLLKLKEALKTSKNKENSLADdlneLNNELQKKQKAYNKILreKDGIDQENDELRRQIKRLSSGLQS-KTLIDNK 1895
Cdd:PRK11281  180 KGGKVGGKALRPSQRVLLQAEQALLN----AQNDLQRKSLEGNTQL--QDLLQKQRDYLTARIQRLEHQLQLlQEAINSK 253

                         250
                  ....*....|....*..
gi 568967308 1896 QslIDELQKKVKKLESQ 1912
Cdd:PRK11281  254 R--LTLSEKTVQEAQSQ 268
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 992-1882 2.27e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.52  E-value: 2.27e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   992 KQYNELTTKYRDiLQKDNMLVQRTSNLEHLEcenaSLKEQMEAISKELEITKEKLHTIEQAWEqETKLGnDSNMDKAKKS 1071
Cdd:TIGR02168  213 ERYKELKAELRE-LELALLVLRLEELREELE----ELQEELKEAEEELEELTAELQELEEKLE-ELRLE-VSELEEEIEE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1072 MTnSDIVSISKKITVLEMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELETKFTELTKINLDAQKVEQMLRDELadsv 1151
Cdd:TIGR02168  286 LQ-KELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAEL---- 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1152 tkavsDADRQRILELEKSEVELKVEVSKLREISDIAKRQVDFLNSQQQSREKEVESL---RTQLLDFQAQSDEKALIAKL 1228
Cdd:TIGR02168  361 -----EELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLedrRERLQQEIEELLKKLEEAEL 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1229 HQHVVSLQISEATalgkLESVTSKLQKMEAYNLRLEQKLDEKEQALYYARlEGRNRAKHLRQTIQSLRRQFSG-----AL 1303
Cdd:TIGR02168  436 KELQAELEELEEE----LEELQEELERLEEALEELREELEEAEQALDAAE-RELAQLQARLDSLERLQENLEGfsegvKA 510

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1304 PLAQQEKFSKTMIQLQnDKLKIMQE----MKNSQQEHRN---MENKTlelelklkGLEELISTLKDARGAQKVINWHVKI 1376
Cdd:TIGR02168  511 LLKNQSGLSGILGVLS-ELISVDEGyeaaIEAALGGRLQavvVENLN--------AAKKAIAFLKQNELGRVTFLPLDSI 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1377 EELRLQelKLNRELVKGKEEIKYLNNIISEYEHTINSLEEEIVQQSKFHEERQMAWDQReveleRQLDifdhQQNEILSA 1456
Cdd:TIGR02168  582 KGTEIQ--GNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELA-----KKLR----PGYRIVTL 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1457 AQKFEDSTGSMPDPSLPLPNQLEIALRKIKENIQVILKTQATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLpa 1536
Cdd:TIGR02168  651 DGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQI-- 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1537 tADREKLIAELERKelepkshhtmkiaHQTIANMQARLNHKEEVLKKYQHLLEKAREEQREIVKKHEEDLhvlhHKLEQQ 1616
Cdd:TIGR02168  729 -SALRKDLARLEAE-------------VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI----EELEAQ 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1617 ADNSLNKFRQTAQDLLKQSPAPVPTNKHFIRLAEMEQTVAEQDDSLSSLLTKLKKVSKDLEKQKEITELKVREFEntklR 1696
Cdd:TIGR02168  791 IEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE----E 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1697 LQETHASEVKKVKAEVEDLRHALAQAHKDSQSLKSELQAQKEANSRAptttmRNLVDRLKSQLA-LKEKQQKALSRaLLE 1775
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSEL-----RRELEELREKLAqLELRLEGLEVR-IDN 940

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1776 LRSEMTAAAEERIIAVTSQKEANLNVQQVVERHTRELKSQIEDLNE-NLLKLKEALKTSKNKENSLA--DDLNELNNELQ 1852
Cdd:TIGR02168  941 LQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPvNLAAIEEYEELKERYDFLTAqkEDLTEAKETLE 1020

                          890       900       910
                   ....*....|....*....|....*....|..
gi 568967308  1853 KKQKAYNKILRE--KDGIDQENDELRRQIKRL 1882
Cdd:TIGR02168 1021 EAIEEIDREARErfKDTFDQVNENFQRVFPKL 1052
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1648-2424 2.89e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.15  E-value: 2.89e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1648 LAEMEQTVAEQDDSLSSLLTKLKKVSKDLEKQKEITEL--KVREFENTKL--RLQETHAS-------------EVKKVKA 1710
Cdd:TIGR02169  179 LEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALlkEKREYEGYELlkEKEALERQkeaierqlasleeELEKLTE 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1711 EVEDLRHALAQAHKDSQSLKSELQAQKEANSRAPTTTMRNL---VDRLKSQLALKEKQQKALSRALLELRSEMTAAAEER 1787
Cdd:TIGR02169  259 EISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELeaeIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEI 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1788 IIAVTSQKEANLNVQQVVERHtRELKSQIEDLNENLLKLKEALKTSKNKENSLADDLNELNNELQKKQKAYNKILREKDG 1867
Cdd:TIGR02169  339 EELEREIEEERKRRDKLTEEY-AELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQR 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1868 IDQENDELRRQIKRLSSGLqsKTLIDNKQSLIDE----------LQKKVKKLESQLERKVDDVDIKPVKEKSSKEELIRW 1937
Cdd:TIGR02169  418 LSEELADLNAAIAGIEAKI--NELEEEKEDKALEikkqewkleqLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEA 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1938 E-EGKKWQTKVEGLRNR---LKEKEGEAHGLAKQLNTLKELFAKA-------------------DKEKLTLQKKLKTTGM 1994
Cdd:TIGR02169  496 EaQARASEERVRGGRAVeevLKASIQGVHGTVAQLGSVGERYATAievaagnrlnnvvveddavAKEAIELLKRRKAGRA 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1995 TVDQVLGVRALESEKELEELKKKNLDLENDILYMRT-----QQALPRDSVVEDLHLQNKYL-QEKLHTLEKKLSKEkySQ 2068
Cdd:TIGR02169  576 TFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKyepafKYVFGDTLVVEDIEAARRLMgKYRMVTLEGELFEK--SG 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2069 SLTSEIESDDHCQKEQELQKENLKLSSENIE-LKFQLEQANKDLPRLKNQVKDLKEMCEFLKKGKLELERKLGQVRG-AG 2146
Cdd:TIGR02169  654 AMTGGSRAPRGGILFSRSEPAELQRLRERLEgLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQeEE 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2147 RSGKTIPELEKTIGLMKKVVEKVQRENEQLKKasgiltseKMATIEEENRNLKAELEKLKAHFGRQLSMQFESKNKGTEK 2226
Cdd:TIGR02169  734 KLKERLEELEEDLSSLEQEIENVKSELKELEA--------RIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEE 805

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2227 IVAENERLRKELKKEIEAS----EKLRIAKNNLELVNDKMAAQLEETGKRLQFAESRAPQLEgadskswksivvsrvyeT 2302
Cdd:TIGR02169  806 EVSRIEARLREIEQKLNRLtlekEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELE-----------------E 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2303 KMKELESDIAKKNQSITDLKQLVREATEREQKAKKYTEDLEQQIEILK-NVPEGAETEQELIRELQLLRLANNQMDKERA 2381
Cdd:TIGR02169  869 ELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRkRLSELKAKLEALEEELSEIEDPKGEDEEIPE 948

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....
gi 568967308  2382 EL--IHQIEINKDQTRADSS---------IPDSDQLKEKINDLETQLRKLELEK 2424
Cdd:TIGR02169  949 EElsLEDVQAELQRVEEEIRalepvnmlaIQEYEEVLKRLDELKEKRAKLEEER 1002
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 79-379 4.37e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 52.38  E-value: 4.37e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308    79 EQAKFENQLKTKVMKLENELEMAQQSAGGRDTRFLRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENE 158
Cdd:TIGR02169  701 ENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEA 780

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   159 NSKLRRENEQLRQDIIdyQKQIDSQKESLLSRRGEDSDYRSQLSKKNYELVQYLDEIQTLTEANEKIEVQNQEMRKNLEE 238
Cdd:TIGR02169  781 LNDLEARLSHSRIPEI--QAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEN 858

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   239 SVQEMEKMTDEYNRMKALVHQSDAVMDQIKKENEHYRLQVRELT---DLLKAKDEEDDPVMMAVNAKVEEWKLILSSKDD 315
Cdd:TIGR02169  859 LNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELErkiEELEAQIEKKRKRLSELKAKLEALEEELSEIED 938

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568967308   316 ---EIIEYQQMLQSLrGKLKnAQLDADKSNIMALK----QGIQERDSQIKMLTEQVEQYTKEMEKNTFIIE 379
Cdd:TIGR02169  939 pkgEDEEIPEEELSL-EDVQ-AELQRVEEEIRALEpvnmLAIQEYEEVLKRLDELKEKRAKLEEERKAILE 1007
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 813-1721 4.53e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 52.37  E-value: 4.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   813 LQELDNKEKKLKHLEDSLEDYNRKFAVIRHQ--QSLLYKEYLSE-----KDIWKTDSEMIREEKRKLEDQAEQDAVKVKE 885
Cdd:TIGR02168  178 ERKLERTRENLDRLEDILNELERQLKSLERQaeKAERYKELKAElreleLALLVLRLEELREELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   886 YNNLLSALQMDSNEMKKMLSENSRKITVLQVNEKSLIRQYTTLVEMERHLRKEngkhRNDVIAMEAEVTEKLGSLQRFKE 965
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRER----LANLERQLEELEAQLEELESKLD 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   966 MAIFKIAALQKVIDnsVSLSELELANKQYNELTTKYRDILQKdnmLVQRTSNLEHLECENASLKEQMEAISKELEITKEK 1045
Cdd:TIGR02168  334 ELAEELAELEEKLE--ELKEELESLEAELEELEAELEELESR---LEELEEQLETLRSKVAQLELQIASLNNEIERLEAR 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1046 LHTIEQAWE--QETKLGNDSNMDKAKKSMTNSDIVSISKKITVLEMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELE 1123
Cdd:TIGR02168  409 LERLEDRRErlQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQ 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1124 TKFTELTKINLDAQKVEQMLRDELADsvtKAVSDADRQRILELEKSEVELKVEVSK---------LREISDIAKRQVDFL 1194
Cdd:TIGR02168  489 ARLDSLERLQENLEGFSEGVKALLKN---QSGLSGILGVLSELISVDEGYEAAIEAalggrlqavVVENLNAAKKAIAFL 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1195 nsqqqsreKEVESLRTQLLDFQAQSDekALIAKLHQHVVSLQISEATALGKLESVTSKLQKMEAYNLRLEQKLDEKEQAL 1274
Cdd:TIGR02168  566 --------KQNELGRVTFLPLDSIKG--TEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNAL 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1275 YYARLEGRnrakhlRQTIQSLRRQFSGALPLAQQEKFSKTMIQLQNDklkimQEMKNSQQEHRNMENKTLELELKLKGLE 1354
Cdd:TIGR02168  636 ELAKKLRP------GYRIVTLDGDLVRPGGVITGGSAKTNSSILERR-----REIEELEEKIEELEEKIAELEKALAELR 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1355 ELISTLKDArgaqkvinwhvkIEELRLQELKLNRELVKGKEEIKYLNNIISEYEHTINSLEEEIVQQSKFHEERQMAWDQ 1434
Cdd:TIGR02168  705 KELEELEEE------------LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEE 772

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1435 REVELERQLDIFDHQQNEIlsaaqkfedstgsmpdpslplpNQLEIALRKIKENIQvilKTQATCKSLEEKLKEKESALR 1514
Cdd:TIGR02168  773 AEEELAEAEAEIEELEAQI----------------------EQLKEELKALREALD---ELRAELTLLNEEAANLRERLE 827

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1515 LAEQNILSRDKVINELRLRLP-ATADREKLIAELERKELEPKSHhtmkiaHQTIANMQARLNHKEEVLKKYQHLLEKARE 1593
Cdd:TIGR02168  828 SLERRIAATERRLEDLEEQIEeLSEDIESLAAEIEELEELIEEL------ESELEALLNERASLEEALALLRSELEELSE 901

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1594 EQREI---VKKHEEDLHVLHHKLEqQADNSLNKFRQTAQDLLKQSpapvpTNKHFIRLAEMEQTVAEQDDSLSSLLTKLK 1670
Cdd:TIGR02168  902 ELRELeskRSELRRELEELREKLA-QLELRLEGLEVRIDNLQERL-----SEEYSLTLEEAEALENKIEDDEEEARRRLK 975

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|.
gi 568967308  1671 KVSKDLEKQKEITELKVREFENTKLRLQEthasevkkVKAEVEDLRHALAQ 1721
Cdd:TIGR02168  976 RLENKIKELGPVNLAAIEEYEELKERYDF--------LTAQKEDLTEAKET 1018
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 429-685 9.59e-06

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 51.08  E-value: 9.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  429 REKDKELVEALkrlkdYESGVYGLEDAVIEIKNckaqikirdgemEVLTKEINKLeMKINDILDENEALRERAGLEPKTM 508
Cdd:PRK05771   15 KSYKDEVLEAL-----HELGVVHIEDLKEELSN------------ERLRKLRSLL-TKLSEALDKLRSYLPKLNPLREEK 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  509 IDLTEFRNSKRLKQQQYRAENqvLLKEIESLEEERLDLKRKIRQMAQERG--KRNAASGLTIDDLNLSETFS------HE 580
Cdd:PRK05771   77 KKVSVKSLEELIKDVEEELEK--IEKEIKELEEEISELENEIKELEQEIErlEPWGNFDLDLSLLLGFKYVSvfvgtvPE 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  581 NKIEGRKLNFMSLNNMNETQSKNETIV------QDLPIQEEQSRNAE---LELDHQRSQAEQNEFLSRELAEKEKDLERS 651
Cdd:PRK05771  155 DKLEELKLESDVENVEYISTDKGYVYVvvvvlkELSDEVEEELKKLGferLELEEEGTPSELIREIKEELEEIEKERESL 234

                         250       260       270
                  ....*....|....*....|....*....|....
gi 568967308  652 RtviakfqSKLKELVEENKQLEEGMKEILQAIKD 685
Cdd:PRK05771  235 L-------EELKELAKKYLEELLALYEYLEIELE 261
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1755-2421 1.24e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 1.24e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1755 LKSQLALKEKQQKALSRALlELRSEmtaaAEERiiavtsQKEANLNVQQVVERHTRELKSQIEDLNENLLKLKEALKTSK 1834
Cdd:COG1196   198 LERQLEPLERQAEKAERYR-ELKEE----LKEL------EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELE 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1835 NKENSLADDLNELNNELQKKQKAYNKILREKDGIDQENDELRRQIKRLssglqsktlidnkQSLIDELQKKVKKLESQLE 1914
Cdd:COG1196   267 AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL-------------EERLEELEEELAELEEELE 333

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1915 RKvddvdikpvkekssKEELIRWEEgkkwqtkveglrnRLKEKEGEAHGLAKQLNTLKELFAKADKEKLTLQKklkttgm 1994
Cdd:COG1196   334 EL--------------EEELEELEE-------------ELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE------- 379

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1995 tvdqvlgvRALESEKELEELKKKNLDLENDILYMRTQQAlprdsvvEDLHLQNKYLQEKlhtlekklsKEKYSQSLTSEI 2074
Cdd:COG1196   380 --------ELEELAEELLEALRAAAELAAQLEELEEAEE-------ALLERLERLEEEL---------EELEEALAELEE 435

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2075 ESDDHCQKEQELQKENLKLSSENIELKFQLEQANKDLPRLKNQVKDLKEMCEFLKKGKLELERKLGQVRGAGRSGKTIPE 2154
Cdd:COG1196   436 EEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALL 515

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2155 LEKTIGLMKKVVEKVQRENEQLKKASGILTSEKMATIEEENRNLKAELEKLKAHFGRQLSmqFESKNKGTEKIVAENERL 2234
Cdd:COG1196   516 LAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAT--FLPLDKIRARAALAAALA 593

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2235 RKELKKEIEASEKLRIAKNNLELVNDKMAAQLEETGKRLQFAESRAPQLEGADSKswKSIVVSRVYETKMKELESDIAKK 2314
Cdd:COG1196   594 RGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLRE--VTLEGEGGSAGGSLTGGSRRELL 671

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2315 NQSITDLKQLVREATEREQKAKKYTEDLEQQIEILKnvpEGAETEQELIRELQLLRLANNQMDKERAELIHQIEINKDQT 2394
Cdd:COG1196   672 AALLEAEAELEELAERLAEEELELEEALLAEEEEER---ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELL 748

                         650       660       670
                  ....*....|....*....|....*....|..
gi 568967308 2395 RAD-----SSIPDSDQLKEKINDLETQLRKLE 2421
Cdd:COG1196   749 EEEaleelPEPPDLEELERELERLEREIEALG 780
Mitofilin pfam09731
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ...
 1583-1987 1.38e-05

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.


Pssm-ID: 430783 [Multi-domain]  Cd Length: 618  Bit Score: 50.53  E-value: 1.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1583 KYQHLLEKAREEQREIVKKHEEDLHVLHHKLEQQADnslnKFRQTAQDLLKQSPAPVPTNKHFIRLAEMEQTVA------ 1656
Cdd:pfam09731   31 NFRDFFEEYIPYGEEVVLYALGEDPPLAPKPKTFRP----LQPSVVSAVTGESKEPKEEKKQVKIPRQSGVSSEvaeeek 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1657 -EQDDSLSSLLTKLKKVSKDLEKQKEITELKVREFENTKLRLQETHASEVKKVKAEVEDLRHALAQAHKDSQSLKSELQA 1735
Cdd:pfam09731  107 eATKDAAEAKAQLPKSEQEKEKALEEVLKEAISKAESATAVAKEAKDDAIQAVKAHTDSLKEASDTAEISREKATDSALQ 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1736 QKEANSRAPTTTM----RNLVDRLKSQLALKEKQQKALSRALLELRSEMTAAAEERIIAVTSQKEANLNVQQVVerhtRE 1811
Cdd:pfam09731  187 KAEALAEKLKEVInlakQSEEEAAPPLLDAAPETPPKLPEHLDNVEEKVEKAQSLAKLVDQYKELVASERIVFQ----QE 262

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1812 LKSQIEDLNENLlklKEALKTSKNKENSLAD----DLNELNNELQKKQKAYNKilREKDGIDQENDELRRQIKRLSSGLQ 1887
Cdd:pfam09731  263 LVSIFPDIIPVL---KEDNLLSNDDLNSLIAhahrEIDQLSKKLAELKKREEK--HIERALEKQKEELDKLAEELSARLE 337

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1888 SKTLIDNKQsLIDELQKKV--------KKLESQLERKVDDVDIKPVKEKSSKEELIRWEEGKKWQTKVEGLRNRLKEKEG 1959
Cdd:pfam09731  338 EVRAADEAQ-LRLEFEREReeiresyeEKLRTELERQAEAHEEHLKDVLVEQEIELQREFLQDIKEKVEEERAGRLLKLN 416

                          410       420
                   ....*....|....*....|....*...
gi 568967308  1960 EAHGLAKQLNTLKELFAKADKEKLTLQK 1987
Cdd:pfam09731  417 ELLANLKGLEKATSSHSEVEDENRKAQQ 444
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
113-556 2.08e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.04  E-value: 2.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  113 LRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENENSKLRRENEQLRQDIIDYQKQIDSQKESLLSRRG 192
Cdd:PRK02224  277 LAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEE 356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  193 EDSDYRSQLSKKNYELVQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDeynrmkalvhqsdavmdqikkene 272
Cdd:PRK02224  357 RAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAED------------------------ 412

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  273 hyrlqvrELTDLLKAKDEeddpvmmaVNAKVEEWKLILSSKDDEIIEYQQMLQSlrGKLKNAQLDADKSNIMAlkqGIQE 352
Cdd:PRK02224  413 -------FLEELREERDE--------LREREAELEATLRTARERVEEAEALLEA--GKCPECGQPVEGSPHVE---TIEE 472

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  353 RDSQIKMLTEQVEQYTKEmekntfiIEDLKNELQKDKGTSnfyqqthymKIHSKVQILEEKTKEAERIAELAEADAREKD 432
Cdd:PRK02224  473 DRERVEELEAELEDLEEE-------VEEVEERLERAEDLV---------EAEDRIERLEERREDLEELIAERRETIEEKR 536

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  433 KELVEALKRLKDYESGVYGLEDAV----IEIKNCKAQIKIRDGEMEVLTKEINKLEmKINDILDENEALRERAGLEPKTM 508
Cdd:PRK02224  537 ERAEELRERAAELEAEAEEKREAAaeaeEEAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEIERLREKR 615

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 568967308  509 IDLTEFRNSKRLKQQQYRAENQVLLkeiESLEEERLDLKRKIRQMAQE 556
Cdd:PRK02224  616 EALAELNDERRERLAEKRERKRELE---AEFDEARIEEAREDKERAEE 660
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1393-2284 3.14e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 49.73  E-value: 3.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1393 GKEEIKylnNIISEYEHTINSLEEEIVQQSKFHEERQMAWDQREVELERQLDIFDHQQNEILSAAQKFEDSTGSmpdpsl 1472
Cdd:pfam15921   72 GKEHIE---RVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQED------ 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1473 pLPNQLEIALRKIKeniqvilktqaTCKSL-EEKLKEKESALRLAEQNILSRDKVINELRLRLP--ATADREKL-----I 1544
Cdd:pfam15921  143 -LRNQLQNTVHELE-----------AAKCLkEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVdfEEASGKKIyehdsM 210

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1545 AELERKELEPKSHHTMKIAHQTIANMQARLNHKEEVLK--------KYQHLLEKAREEQREIVKKHEEDLHVLHHKlEQQ 1616
Cdd:pfam15921  211 STMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEalksesqnKIELLLQQHQDRIEQLISEHEVEITGLTEK-ASS 289

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1617 ADNSLNKFRqtAQDLLKQSPAPVPTNKHFIRLAEMEQTVAEQDDSLSSLLTKLKKVSKDLEKQKEITelkvrefeNTKLR 1696
Cdd:pfam15921  290 ARSQANSIQ--SQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLA--------NSELT 359

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1697 LQETHASEVKKVKAEVED-LRHALAQAHKDSQslksELQAQKEANSRAPTTTMRN--LVDRLKSQLALKEKQQKALSRAL 1773
Cdd:pfam15921  360 EARTERDQFSQESGNLDDqLQKLLADLHKREK----ELSLEKEQNKRLWDRDTGNsiTIDHLRRELDDRNMEVQRLEALL 435

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1774 LELRSEMTAAAEERIIAVTSQKEANLNVQQvverhtreLKSQIEDLNENLLKLKEALKTSKNKENSLADDLNELNNELQK 1853
Cdd:pfam15921  436 KAMKSECQGQMERQMAAIQGKNESLEKVSS--------LTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQE 507

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1854 KQKAynkilrekdgidqendelrrqikrlssglqsktlidnkqslIDELQKKVKKLESQLerkvdDVDIKPVKEKSSKEE 1933
Cdd:pfam15921  508 KERA-----------------------------------------IEATNAEITKLRSRV-----DLKLQELQHLKNEGD 541

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1934 LIRweegkKWQTKVEGLRNRLKEKEGEAHGLAKQLNTLKELFAKADK-------EKLTLQKKLKTTGMTVdQVLGVRALE 2006
Cdd:pfam15921  542 HLR-----NVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRtagamqvEKAQLEKEINDRRLEL-QEFKILKDK 615

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2007 SEKELEELKKKNLDLENDILYMrTQQALPRDSVVEDLHLQNKYLQEKLHTLEKKLSkekysqSLTseiesddhcqKEQEL 2086
Cdd:pfam15921  616 KDAKIRELEARVSDLELEKVKL-VNAGSERLRAVKDIKQERDQLLNEVKTSRNELN------SLS----------EDYEV 678

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2087 QKENLKLSSENIE-----LKFQLEQANKDLPRLKNQVKDLKEMCEFLKKGKLELERKLGQVRGagrsgkTIPELEKTIGL 2161
Cdd:pfam15921  679 LKRNFRNKSEEMEtttnkLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRG------QIDALQSKIQF 752

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2162 MKKVVEKVQRENEQLKKASGILtSEKMATIEEENRNLKAELEKLKAhfgrqlsmqfesknkgtekivaENERLRKELKke 2241
Cdd:pfam15921  753 LEEAMTNANKEKHFLKEEKNKL-SQELSTVATEKNKMAGELEVLRS----------------------QERRLKEKVA-- 807

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|...
gi 568967308  2242 ieaseklriaknNLELVNDKMAAQLEETGKRLQFAESRAPQLE 2284
Cdd:pfam15921  808 ------------NMEVALDKASLQFAECQDIIQRQEQESVRLK 838
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1016-1553 3.67e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.16  E-value: 3.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1016 SNLEHLEcENASLKEQMEAISKELEITK--EKLHTIEQAWEQETKLGNDSNMDKAKKSMTNSDIVSISKKITVLEMKELN 1093
Cdd:COG1196   200 RQLEPLE-RQAEKAERYRELKEELKELEaeLLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEE 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1094 ERQRAEHCQKMYEHLRTSLKQME-------ERNFELETKFTELTKINLDAQKVEQMLRDELADSVTKAVSDADRQRILEL 1166
Cdd:COG1196   279 LELELEEAQAEEYELLAELARLEqdiarleERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEA 358

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1167 EKSEVELKvEVSKLREISDIAKRQVDFLNSQQQSREKEVESLRTQLLDFQAQSDEKALIAKLHQHVVSLQISEATALGKL 1246
Cdd:COG1196   359 ELAEAEEA-LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEE 437

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1247 ESVTSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQSLRRqfsgalpLAQQEKFSKTMIQLQNDKLKIM 1326
Cdd:COG1196   438 EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE-------AAARLLLLLEAEADYEGFLEGV 510

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1327 QEMKNSQQ---------EHRNMENKTLELELKLKGLEELISTLKDARGAQKVINWHVKIEELRLQELKLNRELVKGKEEI 1397
Cdd:COG1196   511 KAALLLAGlrglagavaVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAA 590

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1398 KYLNNIISEYEHTINSLEEEivqqskfHEERQMAWDQREVELERQLDIFDHQQNEILSAAQKFEDSTGSMPDpSLPLPNQ 1477
Cdd:COG1196   591 ALARGAIGAAVDLVASDLRE-------ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEG-GSAGGSL 662

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568967308 1478 LEIALRKIKENIQVILKTQATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATADREKLIAELERKELE 1553
Cdd:COG1196   663 TGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELL 738
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1573-2421 3.88e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.30  E-value: 3.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1573 RLNHKEEVLKKYQHLLEKARE-EQREIVKKHEEdlhvlHHKLEQQADNSLNKFRQTAQDLLKQSPApvpTNKHFIRLAEM 1651
Cdd:TIGR02169  202 RLRREREKAERYQALLKEKREyEGYELLKEKEA-----LERQKEAIERQLASLEEELEKLTEEISE---LEKRLEEIEQL 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1652 EQTVAEQDDSLSS-----LLTKLKKVSKDLEKQKEITELKVREFENTKLRLQETHaSEVKKVKAEVEDLRHALAQAHKDS 1726
Cdd:TIGR02169  274 LEELNKKIKDLGEeeqlrVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLE-AEIDKLLAEIEELEREIEEERKRR 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1727 QSLKSELQAQKEAnsraptttmrnlVDRLKSQLALKEKQQKALSRALLELRSEMTAAAEERiiavtsqkeanlnvqqvve 1806
Cdd:TIGR02169  353 DKLTEEYAELKEE------------LEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI------------------- 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1807 rhtRELKSQIEDLNENLLKLKEALKTSKNKENSLADDLNELNNELQKKQKAYNKILREKDGIDQENDELRRQIKRLssgl 1886
Cdd:TIGR02169  402 ---NELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDL---- 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1887 qsktlidnkQSLIDELQKKVKKLESQLERKvddvdikpvkeKSSKEELIRWEEGKKWQTKVeglrnrLKEKEGEAHGLAK 1966
Cdd:TIGR02169  475 ---------KEEYDRVEKELSKLQRELAEA-----------EAQARASEERVRGGRAVEEV------LKASIQGVHGTVA 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1967 QLNTLKELFAKA-------------------DKEKLTLQKKLKTTGMTVDQVLGVRALESEKELEELKKKNLDLENDILY 2027
Cdd:TIGR02169  529 QLGSVGERYATAievaagnrlnnvvveddavAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEF 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2028 MRT-----QQALPRDSVVEDLHLQNKYL-QEKLHTLEKKLSKEkySQSLTSEIESDDHCQKEQELQKENLKLSSENIE-L 2100
Cdd:TIGR02169  609 DPKyepafKYVFGDTLVVEDIEAARRLMgKYRMVTLEGELFEK--SGAMTGGSRAPRGGILFSRSEPAELQRLRERLEgL 686

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2101 KFQLEQANKDLPRLKNQVKDLKEMCEflkkgklELERKLGqvrgagrsgktipELEKTIGLMKKVVEKVQRENEQLKkas 2180
Cdd:TIGR02169  687 KRELSSLQSELRRIENRLDELSQELS-------DASRKIG-------------EIEKEIEQLEQEEEKLKERLEELE--- 743

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2181 giltsEKMATIEEENRNLKAELEKLKAhfgrQLSMQFESKNKGTEKIVAENERLRKELKKEIEAS-EKLRIAKNNLELVN 2259
Cdd:TIGR02169  744 -----EDLSSLEQEIENVKSELKELEA----RIEELEEDLHKLEEALNDLEARLSHSRIPEIQAElSKLEEEVSRIEARL 814

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2260 DKMAAQLEETGKRLQFAESRAPQLEgADSKSWKSIVVSRvyETKMKELESDIAKKNQSITDLKQLVREATEREQKAKKYT 2339
Cdd:TIGR02169  815 REIEQKLNRLTLEKEYLEKEIQELQ-EQRIDLKEQIKSI--EKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKER 891

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2340 EDLEQQIEILKNVPEGAETEQELIRELQLLRLANNQMDKERaelIHQIEINKDQTRADSS-IPDSDQLKEKINDLETQLR 2418
Cdd:TIGR02169  892 DELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE---LSEIEDPKGEDEEIPEeELSLEDVQAELQRVEEEIR 968


                   ...
gi 568967308  2419 KLE 2421
Cdd:TIGR02169  969 ALE 971
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1090-1915 3.88e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 49.35  E-value: 3.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1090 KELNERQRAEHCQKMYehLRTSLkqmeernFELETKFTELtkinldaqkveQMLRDELADsVTKAVSDADRQRILELEKS 1169
Cdd:pfam15921   92 RRLNESNELHEKQKFY--LRQSV-------IDLQTKLQEM-----------QMERDAMAD-IRRRESQSQEDLRNQLQNT 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1170 EVELKVEVSKLREISDIAKRQVDFLNSQQQSREKEVESLRTQLLDFQAQSDEKaliakLHQHVvSLQISEATALGKleSV 1249
Cdd:pfam15921  151 VHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKK-----IYEHD-SMSTMHFRSLGS--AI 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1250 TSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQSLRRQF--------SGALPLAQQEKFSKTMIQLQnd 1321
Cdd:pfam15921  223 SKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLiseheveiTGLTEKASSARSQANSIQSQ-- 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1322 kLKIMQEmknsqqehrNMENKTLELELKLKGLEELISTLK-DARGAQKVinWHVKIEELRLQELKLNRELVKGKEEIKYL 1400
Cdd:pfam15921  301 -LEIIQE---------QARNQNSMYMRQLSDLESTVSQLRsELREAKRM--YEDKIEELEKQLVLANSELTEARTERDQF 368

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1401 N----NIISEYEHTINSLEEEIVQQSKFHEERQMAWDqREVELERQLDIFDHQQNEILSAAQKFEDSTGSMPDPSLPLPN 1476
Cdd:pfam15921  369 SqesgNLDDQLQKLLADLHKREKELSLEKEQNKRLWD-RDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQME 447

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1477 QLEIALRKIKENIQVILKTQATCKSLEEKLKEKESALRLAEQNILSRDKVINELrlrlpatadreklIAELERKElepks 1556
Cdd:pfam15921  448 RQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDL-------------TASLQEKE----- 509

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1557 hHTMKIAHQTIANMQARLNHKeevLKKYQHLlekareeqreivkKHEEDlHVLHHKLEQQADNSLNKFRQTAQDLLKQsp 1636
Cdd:pfam15921  510 -RAIEATNAEITKLRSRVDLK---LQELQHL-------------KNEGD-HLRNVQTECEALKLQMAEKDKVIEILRQ-- 569

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1637 apvptnkhfiRLAEMEQTVAEQDDSLSSLLTKLKKVSKDL-EKQKEITELKV-REFENTKLRLQETHASE---------- 1704
Cdd:pfam15921  570 ----------QIENMTQLVGQHGRTAGAMQVEKAQLEKEInDRRLELQEFKIlKDKKDAKIRELEARVSDlelekvklvn 639

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1705 --------VKKVKAEVEDLRHALAQAHKDSQSLKSELQAQKEaNSRAPTTTMRNLVDRLKSQLalkEKQQKALSRALLEL 1776
Cdd:pfam15921  640 agserlraVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKR-NFRNKSEEMETTTNKLKMQL---KSAQSELEQTRNTL 715

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1777 RSEMTAAAEERIIAVTSQKEANLNvqqvverhtrelKSQIEDLNENLLKLKEALKTSKNKENSLADDLNELNNELqkkqk 1856
Cdd:pfam15921  716 KSMEGSDGHAMKVAMGMQKQITAK------------RGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQEL----- 778

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1857 ayNKILREKDGIDQENDELRRQIKRLSSGLQSKTLIDNKQSL-IDELQKKVKKLESQLER 1915
Cdd:pfam15921  779 --STVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLqFAECQDIIQRQEQESVR 836
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1660-2136 3.96e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.29  E-value: 3.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1660 DSLSSLLTKLKKVSKDLEKQKEITELKVREFENtKLRLQETHASEVKKVKAEVEDLRHALAQAHKDSQSLKSELQAQKEA 1739
Cdd:PRK03918  234 EELKEEIEELEKELESLEGSKRKLEEKIRELEE-RIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREI 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1740 NSRAPT-TTMRNLVDRLKSQLALKEKQQKALSRALLELRSEMtAAAEERIIAVTSQKEANLNVQQVVERHTRElksQIED 1818
Cdd:PRK03918  313 EKRLSRlEEEINGIEERIKELEEKEERLEELKKKLKELEKRL-EELEERHELYEEAKAKKEELERLKKRLTGL---TPEK 388

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1819 LNENLLKLKEALKTSKNKENSLADDLNELNNELQKKQKAYNKIL----------REKDGIDQEN--DELRRQIKRLSSGL 1886
Cdd:PRK03918  389 LEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgkcpvcgRELTEEHRKEllEEYTAELKRIEKEL 468

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1887 qsKTLIDNKQSLIDELQKKVKKLESQLERKVDDVDIKPVKEKSSKEELIRWEEGKKWQTKVEGLRNRLKEKEGEAHGLAK 1966
Cdd:PRK03918  469 --KEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKK 546

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1967 QLNTLKELfakaDKEKLTLQKKLKTTGMTVDQVLGVRALESEKELEELKKKNLDLENdiLYMRTQQALPRDSVVEDLHLQ 2046
Cdd:PRK03918  547 ELEKLEEL----KKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEP--FYNEYLELKDAEKELEREEKE 620

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2047 NKYLQEKLHTLEKKLSK-EKYSQSLTSEIESDDHCQKEQE---LQKENLKLSSENIELKFQLEQANKDLPRLKNQVKDLK 2122
Cdd:PRK03918  621 LKKLEEELDKAFEELAEtEKRLEELRKELEELEKKYSEEEyeeLREEYLELSRELAGLRAELEELEKRREEIKKTLEKLK 700

                         490
                  ....*....|....
gi 568967308 2123 EMCEFLKKGKLELE 2136
Cdd:PRK03918  701 EELEEREKAKKELE 714
PTZ00121 PTZ00121
MAEBL; Provisional
 16-422 4.09e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.37  E-value: 4.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   16 DDLPRQEELadKLLISLSKVEVNELKNEDQENMIHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLE 95
Cdd:PTZ00121 1549 DELKKAEEL--KKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELK 1626

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   96 NELEMaqqsaggrdtrflRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENENSKLRRENEQLRQDIID 175
Cdd:PTZ00121 1627 KAEEE-------------KKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEA 1693

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  176 YQKQIDSQKESLLSRRGEDSDYRSQLSKKNYELVQYLDEIQTLTEANEKiEVQNQEMRKNLEESVQEMEKMTDEYNRMKA 255
Cdd:PTZ00121 1694 LKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED-KKKAEEAKKDEEEKKKIAHLKKEEEKKAEE 1772

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  256 LVHQSDAVMDQ-IKKENEHYRLQVRELTDLLKAKDEEDDPVMMAVNAKVEEWKLILSSKDDEIIEYQQMlqsLRGKLKNA 334
Cdd:PTZ00121 1773 IRKEKEAVIEEeLDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNM---QLEEADAF 1849

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  335 QLDADKSNIMALKQGIQERDSQIKmlTEQVEQYTKEMEKNTFIIEDLKNELQKDKGTSNfYQQTHYMKIHSKVQILEEKT 414
Cdd:PTZ00121 1850 EKHKFNKNNENGEDGNKEADFNKE--KDLKEDDEEEIEEADEIEKIDKDDIEREIPNNN-MAGKNNDIIDDKLDKDEYIK 1926


                  ....*...
gi 568967308  415 KEAERIAE 422
Cdd:PTZ00121 1927 RDAEETRE 1934
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 988-1297 4.20e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.16  E-value: 4.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  988 ELANKQYNELTTKYRDILQKdnmLVQRTSNLEHLECENASLKEQMEAISKELEITKEKLHTIEQAWEQEtklgndsnmdK 1067
Cdd:COG1196   221 ELKELEAELLLLKLRELEAE---LEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEA----------Q 287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1068 AKKSMTNSDIVSISKKITVLEMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELETKFTELTKINLDAQKVEQMLRDEL 1147
Cdd:COG1196   288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1148 ADSVTKAVS-----DADRQRILELEKSEVELKVEVSKL-REISDIAKRQVDFLNSQQQSREKEVESLRTQLLDFQAQSDE 1221
Cdd:COG1196   368 LEAEAELAEaeeelEELAEELLEALRAAAELAAQLEELeEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568967308 1222 KALIAKLHQHVVSLQISEATALGKLESVTSKLQKMEAYNLRLEQKLDEKEQALyyARLEGRNRAKHLRQTIQSLRR 1297
Cdd:COG1196   448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE--ADYEGFLEGVKAALLLAGLRG 521
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 78-233 4.59e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.91  E-value: 4.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308    78 EEQAKFENQLKTKVMKLENELEMAQQSAGGRDTRF--LRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEA 155
Cdd:TIGR02169  346 EEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFaeTRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADL 425

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568967308   156 ENENSKLRRENEQLRQDIIDYQKQIDSQKESLLSRRGEDSDYRSQLSKKNYELVQYLDEIQTLTEANEKIEVQNQEMR 233
Cdd:TIGR02169  426 NAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASE 503
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1781-1982 4.70e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 48.29  E-value: 4.70e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1781 TAAAEERIIAVTSQKEANLNVQQVVERHTRELKSQIEDLNENLLKLKEALKTSKNKENSLADDLNELNNELQKKQKAYNK 1860
Cdd:COG3883    11 PAFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGE 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1861 ILRE--KDGIDQ-------ENDELRRQIKRLSSglqSKTLIDNKQSLIDELQKKVKKLE---SQLERKVDDVDIKPVKEK 1928
Cdd:COG3883    91 RARAlyRSGGSVsyldvllGSESFSDFLDRLSA---LSKIADADADLLEELKADKAELEakkAELEAKLAELEALKAELE 167

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 568967308 1929 SSKEELIRWEEGKkwQTKVEGLRNRLKEKEGEAHGLAKQLNTLKELFAKADKEK 1982
Cdd:COG3883   168 AAKAELEAQQAEQ--EALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAA 219
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1609-1881 9.72e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.99  E-value: 9.72e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1609 LHHKLEQQADNSLNKFRQTaqdllkQSPAPVPTNKHFIRlAEM--EQTVAEQDDSLSSLLTKLKKVSKDLEKQKEITELk 1686
Cdd:COG4913   182 LRRRLGIGSEKALRLLHKT------QSFKPIGDLDDFVR-EYMleEPDTFEAADALVEHFDDLERAHEALEDAREQIEL- 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1687 vrefentkLRLQETHASEVKKVKAEVEDLRHALAQAHKDSQSLKSELQAQKEANSRAptttmrnLVDRLKSQLALKEKQQ 1766
Cdd:COG4913   254 --------LEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRA-------ELARLEAELERLEARL 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1767 KALSRALLELRSEMTAAAEERIIAVTSQKEANLNVQQVVERHTRELKSQI-----------EDLNENLLKLKEALKTSKN 1835
Cdd:COG4913   319 DALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLaalglplpasaEEFAALRAEAAALLEALEE 398

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 568967308 1836 KENSLADDLNELNNELQKKQKAYNKILREKDG-------IDQENDELRRQIKR 1881
Cdd:COG4913   399 ELEALEEALAEAEAALRDLRRELRELEAEIASlerrksnIPARLLALRDALAE 451
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 113-281 1.02e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 1.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  113 LRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENENSKLRRENEQLRQDIIDYQKQIDSQKESL----- 187
Cdd:COG4942    32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELaellr 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  188 -LSRRGEDSDYRSQLSKKN-------YELVQYL-----DEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMK 254
Cdd:COG4942   112 aLYRLGRQPPLALLLSPEDfldavrrLQYLKYLaparrEQAEELRADLAELAALRAELEAERAELEALLAELEEERAALE 191

                         170       180
                  ....*....|....*....|....*..
gi 568967308  255 ALVHQSDAVMDQIKKENEHYRLQVREL 281
Cdd:COG4942   192 ALKAERQKLLARLEKELAELAAELAEL 218
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1375-1914 1.12e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.75  E-value: 1.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1375 KIEELRLQELKLNRELVKGKEEIKYLNNIISEYEHTINSLEEEIVQQSKFHEERqmawdQREVELERQLDIFDHQQNEIL 1454
Cdd:PRK03918  239 EIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKA-----EEYIKLSEFYEEYLDELREIE 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1455 SAAQKFEDstgsmpdpslpLPNQLEIALRKIKENIQVILKTQATCKSLEEKLKEKESALRLAEQnILSRDKVINELRLRL 1534
Cdd:PRK03918  314 KRLSRLEE-----------EINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEE-AKAKKEELERLKKRL 381

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1535 pATADREKLIAELERKElepKSHHTMKIAHQTIANMQARLNHKEEVLKKYQHLLEKAREE----QREIVKKHEEDLhvlh 1610
Cdd:PRK03918  382 -TGLTPEKLEKELEELE---KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcGRELTEEHRKEL---- 453

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1611 hkleqqadnslnkfrqtaqdllkqspapvpTNKHFIRLAEMEQTVAEQDDSLSSLLTKLKKVSKDLEKQKEITELK--VR 1688
Cdd:PRK03918  454 ------------------------------LEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKelAE 503

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1689 EFENTKLRLQETHASEVKKVKAEVEDLRHALAQAHKDSQSLKSELQAQKEANSRAPTttmrnlvdrLKSQLALKEKQQKA 1768
Cdd:PRK03918  504 QLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAE---------LEKKLDELEEELAE 574

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1769 LSRALLELRSEMTAAAEERIIAVTSQKEANLNVQQVverhtrelKSQIEDLNENLLKLKEALKTSKNKENSLADDLNELN 1848
Cdd:PRK03918  575 LLKELEELGFESVEELEERLKELEPFYNEYLELKDA--------EKELEREEKELKKLEEELDKAFEELAETEKRLEELR 646

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568967308 1849 NELQKKQKAYNKilREKDGIDQENDELRRQIKRLSSGLQSktlidnKQSLIDELQKKVKKLESQLE 1914
Cdd:PRK03918  647 KELEELEKKYSE--EEYEELREEYLELSRELAGLRAELEE------LEKRREEIKKTLEKLKEELE 704
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1477-1987 1.15e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.75  E-value: 1.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1477 QLEIALRKIKENIQVILKTQATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATADREKLIAELERKELE--- 1553
Cdd:PRK03918  218 ELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEyik 297

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1554 -PKSHHTMKIAHQTIANMQARLNHKEEVLKKYQHLLEKAREEQREIVKKHEEDLHVL-----HHKLEQQADNSLNKFRQT 1627
Cdd:PRK03918  298 lSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLeeleeRHELYEEAKAKKEELERL 377

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1628 AQDLLKQSPAPVPTNKHFIRLAEME-----QTVAEQDDSLSSLLTKLKKVSKDLEKQKEITELKVREF-ENTKLRLQETH 1701
Cdd:PRK03918  378 KKRLTGLTPEKLEKELEELEKAKEEieeeiSKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELtEEHRKELLEEY 457

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1702 ASEVKKVKAEVEDLRHALAQAHKDSQSLKSELQAQKEansrapTTTMRNLVDRLKSQlalkEKQQKALSRALLELRSEMT 1781
Cdd:PRK03918  458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKESE------LIKLKELAEQLKEL----EEKLKKYNLEELEKKAEEY 527

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1782 AAAEERIIAVTSQKEanlNVQQVVERhTRELKSQIEDLNENLLKLKEALKTSKNKENSLA-DDLNELNNELQKKQKAYNK 1860
Cdd:PRK03918  528 EKLKEKLIKLKGEIK---SLKKELEK-LEELKKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEPFYNE 603

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1861 ILREKDGidqeNDELRRQIKRLSSglqSKTLIDNKQSLIDELQKKVKKLESQLERKVDDVDIKPVKEKSSKEELIRWEeg 1940
Cdd:PRK03918  604 YLELKDA----EKELEREEKELKK---LEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRE-- 674

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*..
gi 568967308 1941 kkwqtkVEGLRNRLKEKEGEAHGLAKQLNTLKELFAKADKEKLTLQK 1987
Cdd:PRK03918  675 ------LAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEK 715
PTZ00121 PTZ00121
MAEBL; Provisional
 1167-1992 1.17e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.83  E-value: 1.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1167 EKSEVELKVEVSKLREISDIAKRQVDFLNSQQQSREKEVESLRTQLLDFQAQSDEKALIAKLHQHVVSL-QISEATALGK 1245
Cdd:PTZ00121 1031 ELTEYGNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKaEEAKKTETGK 1110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1246 LESVTSKLQKM----EAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQSLRRQFSGALPLAQQEKFSKTMIQLQND 1321
Cdd:PTZ00121 1111 AEEARKAEEAKkkaeDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKA 1190

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1322 KLKIMQEMKNSQQEHRNMENKTLELELKLKGLEELISTLKDARGAQKvinwhvKIEELRLQELKLNRELVKGKEEIKYLN 1401
Cdd:PTZ00121 1191 EELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKK------DAEEAKKAEEERNNEEIRKFEEARMAH 1264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1402 niISEYEHTINSLEEEIVQQSKFHEERQMAWDQREVELERQLDifdhqqneilSAAQKFEDStgsmpdpslplpNQLEIA 1481
Cdd:PTZ00121 1265 --FARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKAD----------EAKKKAEEA------------KKADEA 1320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1482 LRKIKENIQvilKTQATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATADREKLIAELERKELEPKSHHTMK 1561
Cdd:PTZ00121 1321 KKKAEEAKK---KADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAK 1397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1562 IAHQTIANMQARLNHKEEVLKKYQHLLEKAREEQR--EIVKKHEEdlhvlhhkleqqadnslnkfRQTAQDLLKQSPAPv 1639
Cdd:PTZ00121 1398 KKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKadEAKKKAEE--------------------AKKADEAKKKAEEA- 1456

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1640 ptnkhfiRLAEMEQTVAEQDDSLSSLLTKLKKVSKDLEKQKEITELKVREFENTKLRLQETHASEVKKV--KAEVEDLRH 1717
Cdd:PTZ00121 1457 -------KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAeeAKKADEAKK 1529

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1718 AlAQAHKDSQSLKSELQAQKEANSRAPTTTMRNLVDRLKSQLALKEKQQKALSRAllelrSEMTAAAEERIIAVTSQKEA 1797
Cdd:PTZ00121 1530 A-EEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKA-----EEAKKAEEARIEEVMKLYEE 1603

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1798 NLNVQQVVERHTRELKSQIEDLNE--------NLLKLKEALKTSKNKENSLADDLNELNNELQKKQKAYNKilREKDGID 1869
Cdd:PTZ00121 1604 EKKMKAEEAKKAEEAKIKAEELKKaeeekkkvEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDK--KKAEEAK 1681

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1870 QENDELRRQIKRLSSGLQSKTLIDNKQSLIDELQKK---VKKLESQLERKVDDVDIKPVKEKSSKEELIRWEEGKKwqtK 1946
Cdd:PTZ00121 1682 KAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKaeeLKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKK---K 1758

                         810       820       830       840
                  ....*....|....*....|....*....|....*....|....*.
gi 568967308 1947 VEGLRnRLKEKEGEAHGLAKQLNTLKELFAKADKEKLTLQKKLKTT 1992
Cdd:PTZ00121 1759 IAHLK-KEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDI 1803
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 113-291 1.32e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 46.75  E-value: 1.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  113 LRDEIRQLEKQLEQKDRELEDMEKELDkekKVNEQLalrnEEAENENSKLRRENEQLRQDIIDYQKQIDSQKESL----- 187
Cdd:COG3883    21 KQKELSELQAELEAAQAELDALQAELE---ELNEEY----NELQAELEALQAEIDKLQAEIAEAEAEIEERREELgerar 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  188 -LSRRGEDSDYRSQL--SKKNYELVQYLDEIQTLTEANEKI-------EVQNQEMRKNLEESVQEMEKMTDEYNRMK--- 254
Cdd:COG3883    94 aLYRSGGSVSYLDVLlgSESFSDFLDRLSALSKIADADADLleelkadKAELEAKKAELEAKLAELEALKAELEAAKael 173

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 568967308  255 -ALVHQSDAVMDQIKKENEHYRLQVRELTDLLKAKDEE 291
Cdd:COG3883   174 eAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAA 211
PTZ00121 PTZ00121
MAEBL; Provisional
 2059-2481 2.14e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.06  E-value: 2.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2059 KKLSKEKYSQSLTSEIESDDHCQKEQELQKENLKLSSENIELKFQLEQANKDLPRLKNQVKDLKEMCEFLKKGKlELERK 2138
Cdd:PTZ00121 1348 AKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKAD-EAKKK 1426

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2139 LGQVRGAGRSGKTIPELEKTIGLMKKVVEKVQRENEQlKKASGILTSEKMATIEEENRNL-----KAELEKLKAHFGRQL 2213
Cdd:PTZ00121 1427 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAK-KKAEEAKKADEAKKKAEEAKKAdeakkKAEEAKKKADEAKKA 1505

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2214 S---------MQFESKNKGTEKIVAENERLRKELKK--EIEASEKLRIAKNNLELVNDKMAAQLEETGKRLQFAESRAPQ 2282
Cdd:PTZ00121 1506 AeakkkadeaKKAEEAKKADEAKKAEEAKKADEAKKaeEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEE 1585

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2283 LEGADSKSWKSIVVSRVYETKMK-------ELESDIAKKNQSITDLKQLVREATEREQKAKKYTEDLEQQIEILK-NVPE 2354
Cdd:PTZ00121 1586 AKKAEEARIEEVMKLYEEEKKMKaeeakkaEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKiKAAE 1665

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2355 GAETEQELIRELQLLRLANNQMDKERAELIHQIEINKD----QTRADSSIPDSDQLK--EKINDLETQLRKLELEKQHSK 2428
Cdd:PTZ00121 1666 EAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKaeelKKKEAEEKKKAEELKkaEEENKIKAEEAKKEAEEDKKK 1745

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 568967308 2429 EEVKKLKKELENFDPSFFEEIEDLKYNYKEEvkKNILLEEKLKKLSEQFGFEL 2481
Cdd:PTZ00121 1746 AEEAKKDEEEKKKIAHLKKEEEKKAEEIRKE--KEAVIEEELDEEDEKRRMEV 1796
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 149-376 2.19e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 2.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  149 ALRNEEAENENSKLRRENEQLRQDIIDYQKQIDSQKESLLSRRGEDSDYRSQLSKKNYELVQYLDEIQTLTEANEKIEVQ 228
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  229 NQEMRKNLEESVQEMEKMtDEYNRMKALVHQSD------------AVMDQIKKENEHYRLQVRELTDLLKAKDEEDDPVM 296
Cdd:COG4942    99 LEAQKEELAELLRALYRL-GRQPPLALLLSPEDfldavrrlqylkYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  297 MAVNAKVEEWKLILSSKDdeiiEYQQMLQSLrgklkNAQLDADKSNIMALKQGIQERDSQIKMLTEQVEQYTKEMEKNTF 376
Cdd:COG4942   178 ALLAELEEERAALEALKA----ERQKLLARL-----EKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGF 248
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 30-493 2.88e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.17  E-value: 2.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308    30 ISLSKVEVNELKNEDQENMIHLFRITQSLMKMKAQEVELALEEvekagEEQAKFENQLKTKVMKLENELEMAQQSAGGRD 109
Cdd:TIGR04523  234 IEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKEL-----EQNNKKIKELEKQLNQLKSEISDLNNQKEQDW 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   110 TRFLRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENENSKLRRENEQLRQDIIDYQKQIDSQKESLLS 189
Cdd:TIGR04523  309 NKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKN 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   190 RRGEDSDYRSQLSKKNYELVQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKALVHQSDAVMDQIKK 269
Cdd:TIGR04523  389 LESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLET 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   270 ENEHYRLQVRELTDLLKAKDEEDdpvmmavnakveewklilsskddeiieyqqmlqslrgKLKNAQLDADKSNIMALKQG 349
Cdd:TIGR04523  469 QLKVLSRSINKIKQNLEQKQKEL-------------------------------------KSKEKELKKLNEEKKELEEK 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   350 IQERDSQIKMLTEQVEQYTKEMEKNTFIIEDLKNELQKDKGTSNFYQ-QTHYMKIHSKVQILEEKTKEAERIAELAEADA 428
Cdd:TIGR04523  512 VKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENlEKEIDEKNKEIEELKQTQKSLKKKQEEKQELI 591

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568967308   429 REKDKELVEALKRLKDYESGVYGLEDAVIEIKNCKAQIKIRDGEMEVLTKEINKLEMKINDILDE 493
Cdd:TIGR04523  592 DQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKE 656
PTZ00121 PTZ00121
MAEBL; Provisional
 79-582 3.15e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.29  E-value: 3.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   79 EQAKFENQLKTKVMKLENELEMAQQSAGGrdtrfLRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENE 158
Cdd:PTZ00121 1305 DEAKKKAEEAKKADEAKKKAEEAKKKADA-----AKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKK 1379

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  159 NSKLRRENEQLRQDIIDYQKQIDSQKESLLSRRGEDSDYRSQLSKKNYELVQYLDEIQTLTEANEKIEvqnqEMRKNLEE 238
Cdd:PTZ00121 1380 ADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKAD----EAKKKAEE 1455

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  239 S--VQEMEKMTDEYNRMKALVHQSDAV--MDQIKKENEHYRLQVRELTDLLKAKDEEDDPVMMAVNAKVEEWKLILSSKD 314
Cdd:PTZ00121 1456 AkkAEEAKKKAEEAKKADEAKKKAEEAkkADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKK 1535

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  315 DEiieyqqmlqslrgKLKNAQldaDKSNIMALKQGIQERDSQIKmltEQVEQYTKEMEKNTFIIEdlKNELQKDKGTSNF 394
Cdd:PTZ00121 1536 AD-------------EAKKAE---EKKKADELKKAEELKKAEEK---KKAEEAKKAEEDKNMALR--KAEEAKKAEEARI 1594

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  395 YQQTHYMKIHSKVQILEEKTKEAERIAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVIEIKNCKAQIKIRDGEME 474
Cdd:PTZ00121 1595 EEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDK 1674

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  475 VLTKEINKLEmkiNDILDENEALRERAGlEPKTMIDLTEFRNSKRLKQQQYRAENQVLLKEIESLEEERLDLKRKIRQMA 554
Cdd:PTZ00121 1675 KKAEEAKKAE---EDEKKAAEALKKEAE-EAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAK 1750

                         490       500
                  ....*....|....*....|....*...
gi 568967308  555 QERGKRNAASGLTIDDLNLSETFSHENK 582
Cdd:PTZ00121 1751 KDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1846-2434 4.62e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.70  E-value: 4.62e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1846 ELNNELQKKQKAYnkILREKDGIDQENDELRRQIKRLssglqsKTLIDNKQSLIDELQKKVKKLESQLERKVDDVDIKPV 1925
Cdd:COG1196   217 ELKEELKELEAEL--LLLKLRELEAELEELEAELEEL------EAELEELEAELAELEAELEELRLELEELELELEEAQA 288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1926 KEKSSKEELIRWEEGKK-WQTKVEGLRNRLKEKEGEAHGLAKQLNTLKELFAKADKEKLTLQKKLKTTGMTVDQVLGVRA 2004
Cdd:COG1196   289 EEYELLAELARLEQDIArLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2005 LESEKELEELKKKNLDLENDILYMRTQQALpRDSVVEDLHLQNKYLQEKLHTLEKKLSKEKysQSLTSEIESDDHCQKEQ 2084
Cdd:COG1196   369 EAEAELAEAEEELEELAEELLEALRAAAEL-AAQLEELEEAEEALLERLERLEEELEELEE--ALAELEEEEEEEEEALE 445

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2085 ELQKENLKLSSENIELKFQLEQANKDLPRLKNQVKDLKEMCEFLKKGKLELERKLGQVRGAGRSGKTIPELEKTIGLMKK 2164
Cdd:COG1196   446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGA 525

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2165 VVEKVQRENEQLKKASGILTSEKMATIEEENRNLKAELEKLKAhfgrqlsmqfesKNKGTEKIVAENERLRKELKKEIEA 2244
Cdd:COG1196   526 VAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA------------AKAGRATFLPLDKIRARAALAAALA 593

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2245 SEKLRIAKNNLELvndkmAAQLEETGKRLQFAESRAPQLEGADSKSWKSIVVSRVYETKMKELESDIAKKNQSITDLKQL 2324
Cdd:COG1196   594 RGAIGAAVDLVAS-----DLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRR 668

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2325 VREATEREQKAKKytEDLEQQIEilknvpEGAETEQELIRELQLLRLANNQMDKERAELIHQIEINKDQTRADSSIPDSD 2404
Cdd:COG1196   669 ELLAALLEAEAEL--EELAERLA------EEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEE 740

                         570       580       590
                  ....*....|....*....|....*....|
gi 568967308 2405 QLKEKINDLETQLRKLELEKqhSKEEVKKL 2434
Cdd:COG1196   741 LLEEEELLEEEALEELPEPP--DLEELERE 768
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1495-2308 5.40e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 45.42  E-value: 5.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1495 TQATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATADREKLIAELERKELEPkSHHTMKIAHQTIANMQARL 1574
Cdd:TIGR00606  236 SREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKV-FQGTDEQLNDLYHNHQRTV 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1575 NHKEEVLKKYQHLLEKAREEQREIVKKHEEdLHVLHHKLEQQADNSLNKFRqtAQDLLKQSPAPVP-------------- 1640
Cdd:TIGR00606  315 REKERELVDCQRELEKLNKERRLLNQEKTE-LLVEQGRLQLQADRHQEHIR--ARDSLIQSLATRLeldgfergpfserq 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1641 -TNKHFIRLAEMEQTVAEQDDSLSSLLTKLKKVSKDLEKQKEITELKVREFENTKLRLqETHASEVKKVKAEVEDLRHAL 1719
Cdd:TIGR00606  392 iKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEIL-EKKQEELKFVIKELQQLEGSS 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1720 AQAHKDSQSLKSELQAQKEANSRAPTTTMRNLVDRLKSQLALKEKQQKALSRALLELRSEMTAAAEERIIAvTSQKEANL 1799
Cdd:TIGR00606  471 DRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLT-KDKMDKDE 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1800 NVQQVVERHTRELKSQIEDLnENLLKLKEALKTSKNKENSLADDLNELNNELQKKQKAYNKILREKD------------- 1866
Cdd:TIGR00606  550 QIRKIKSRHSDELTSLLGYF-PNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELEskeeqlssyedkl 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1867 ----GIDQENDELRRQIKRLSSGLQSKTLIDNKQSLIDE--------------LQKKVKKLESQLERKVDDVDIK----P 1924
Cdd:TIGR00606  629 fdvcGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQfitqltdenqsccpVCQRVFQTEAELQEFISDLQSKlrlaP 708

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1925 VKEKSSKEELIRWE-EGKKWQTKVEGLRNRLKEKEGEAHGLAKQLNTLKELFAKaDKEKLTLQKKLKTTGMTVDQVLGVr 2003
Cdd:TIGR00606  709 DKLKSTESELKKKEkRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQR-LKNDIEEQETLLGTIMPEEESAKV- 786

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2004 ALESEKELEELKKKNLDLENDIlymrTQQALPRDSVVEDLHLQ--NKYLQEKLHTLEKKLSKEKYSQSLtseieSDDHCQ 2081
Cdd:TIGR00606  787 CLTDVTIMERFQMELKDVERKI----AQQAAKLQGSDLDRTVQqvNQEKQEKQHELDTVVSKIELNRKL-----IQDQQE 857

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2082 KEQELQKENLKLSSENIELKFQLEQANKDLPRLKNQVKDLKEMCEFLKKGKLE-----------LERKLGQVRGAGRSGK 2150
Cdd:TIGR00606  858 QIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQdspletflekdQQEKEELISSKETSNK 937

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2151 TI--------PELEKTIGLMKKVVEKVQRENEQLKKASGILTSEKMATIEEE-------NRNLKAELEKLKAHFGRQLSM 2215
Cdd:TIGR00606  938 KAqdkvndikEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECekhqekiNEDMRLMRQDIDTQKIQERWL 1017

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2216 QFESKNKGTEKIVAENERLRKELKKEI-------------EASEKLRIAKNNLELVNDKMAAQLEEtgKRLQFAESRAPQ 2282
Cdd:TIGR00606 1018 QDNLTLRKRENELKEVEEELKQHLKEMgqmqvlqmkqehqKLEENIDLIKRNHVLALGRQKGYEKE--IKHFKKELREPQ 1095

                          890       900
                   ....*....|....*....|....*.
gi 568967308  2283 LEGADSKSWKSIVVSRVYETKMKELE 2308
Cdd:TIGR00606 1096 FRDAEEKYREMMIVMRTTELVNKDLD 1121
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2233-2478 5.67e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.44  E-value: 5.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2233 RLRKELKKEIEASEKLRIAKNNLELVNDKMAAQLEETGKRLQFAESRAPQLEGADSKSWKSIVVSRVYETKMKELESDIA 2312
Cdd:PRK03918  169 EVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELE 248

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2313 KKNQSITDLKQLVREATEREQKAKKYTEDLEQQIEILKNVPEGAETEQELIRELQLLRLANNQMDKERAELIHQI----- 2387
Cdd:PRK03918  249 SLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEIngiee 328

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2388 ---EINKDQTRADSSIPDSDQLKEKINDLETQLRKLELEKQHSKEEVKKLKKELEnfdpsffEEIEDLKYNYKEEVKKNI 2464
Cdd:PRK03918  329 rikELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTG-------LTPEKLEKELEELEKAKE 401

                         250
                  ....*....|....
gi 568967308 2465 LLEEKLKKLSEQFG 2478
Cdd:PRK03918  402 EIEEEISKITARIG 415
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 113-894 7.06e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 45.35  E-value: 7.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   113 LRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENENSKLRRENEQLRQDIIDYQKQIDSQKESLLSRRG 192
Cdd:pfam02463  192 LEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVL 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   193 EDSDYRSQLSK-KNYELVQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKALVHQSDAVMDQIKKEN 271
Cdd:pfam02463  272 KENKEEEKEKKlQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKR 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   272 EHYRLQVRELTDLLKAKDEEDDPVMMAVNAKVEEwklilSSKDDEIIEYQQMLQSLRGKLKNAQLDADKSNIMALKQGIQ 351
Cdd:pfam02463  352 EAEEEEEEELEKLQEKLEQLEEELLAKKKLESER-----LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKK 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   352 ERDSQIKMLTEqveqyTKEMEKNTFIIEDLKNELQKDKGTSNFYQQTHYMKIHSKVQILEEKTKEAERIAELAEADAREK 431
Cdd:pfam02463  427 EELEILEEEEE-----SIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQK 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   432 DKELVEALKRLKDYESGVYGLEDAVIEIKNCKAQIKIRDGEMEVLTKEINKLEMKIndILDENEALRERAGLEPKTMIDL 511
Cdd:pfam02463  502 ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATA--DEVEERQKLVRALTELPLGARK 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   512 TEFRNSKRLKQQQYRAENQVLLKEIESLEEERLDLKRKIRQMAQERGK--RNAASGLTIDDLNLSETFSHENKIEGRKLN 589
Cdd:pfam02463  580 LRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGilKDTELTKLKESAKAKESGLRKGVSLEEGLA 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   590 FMSLNNMNETQSKNETIVQDLPIQEEQSRNAELELdHQRSQAEQNEFLSRELAEKEKDLERSRTVIAKFQSKLKELVEEN 669
Cdd:pfam02463  660 EKSEVKASLSELTKELLEIQELQEKAESELAKEEI-LRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEEL 738

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   670 KQLEEGMKEILQAIKDMPKDSDVKGGETSLIIPSLERLVNAMESKNAEGIFDASLH-LKAQVDQLTGRNEELRQELRQSR 748
Cdd:pfam02463  739 KLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEkLKAQEEELRALEEELKEEAELLE 818

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   749 KEAVNYSQQLVKANLKIDHLEKETDLLRQSAGSNVVYKGIDLpdgiAPSSAYIINSQNEYLIHLLQELDNKEKKLKHLED 828
Cdd:pfam02463  819 EEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLE----EEITKEELLQELLLKEEELEEQKLKDELESKEEK 894

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568967308   829 SLEDYNRKFAVIRHQQSLLYKEYLSEKDIWKTDSEMIREEKRKLEDQAEQDAVKVKEYNNLLSALQ 894
Cdd:pfam02463  895 EKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEE 960
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1851-2422 7.19e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.05  E-value: 7.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1851 LQKKQKAYNKILREKDGIDQENDELRRQIKRLSsglQSKTLIDNKQSLIDELQKKVKKLESQLERKVDDVD--------- 1921
Cdd:PRK03918  157 LDDYENAYKNLGEVIKEIKRRIERLEKFIKRTE---NIEELIKEKEKELEEVLREINEISSELPELREELEklekevkel 233

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1922 --IKPVKEKSSKEELIRWEEGKKWQTKVEGLRNRLKEKEGEAHGLAKQLNTLKELfaKADKEKLTLQKKLKTTGMTVDQV 1999
Cdd:PRK03918  234 eeLKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL--KEKAEEYIKLSEFYEEYLDELRE 311

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2000 LGVRALESEKELEELKKKNLDLENDilymrtqqalprDSVVEDLHLQNKYLQEKLHTLEKKLSKEKYSQSLTSEIE---S 2076
Cdd:PRK03918  312 IEKRLSRLEEEINGIEERIKELEEK------------EERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELErlkK 379

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2077 DDHCQKEQELQKENLKLSSENIELKFQLEQANKDLPRLKNQVKDLKEMCEFLKKGKLELE---RKLGQVRGAGRSGKTIP 2153
Cdd:PRK03918  380 RLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPvcgRELTEEHRKELLEEYTA 459

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2154 ELEKTIGLMKKVVEKVQRENEQLKKASGILTSE----KMATIEEENRNLKAELEKLKAHFGRQLSMQFESKNKGTEKIVA 2229
Cdd:PRK03918  460 ELKRIEKELKEIEEKERKLRKELRELEKVLKKEseliKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKG 539

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2230 ENERLRKELKKEIEASEKLRIAKNNLELVNDKMAA---QLEETG-KRLQFAESRAPQLEGADSKSwksivvsrvyeTKMK 2305
Cdd:PRK03918  540 EIKSLKKELEKLEELKKKLAELEKKLDELEEELAEllkELEELGfESVEELEERLKELEPFYNEY-----------LELK 608

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 2306 ELESDIAKKNQSITDLKQLVREATEREQKAKKYTEDLEQQIEILKNvpEGAETEQELIRELQLlrlannQMDKERAELIH 2385
Cdd:PRK03918  609 DAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEK--KYSEEEYEELREEYL------ELSRELAGLRA 680

                         570       580       590
                  ....*....|....*....|....*....|....*..
gi 568967308 2386 QIEINKDqtRADSSIPDSDQLKEKINDLETQLRKLEL 2422
Cdd:PRK03918  681 ELEELEK--RREEIKKTLEKLKEELEEREKAKKELEK 715
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 223-500 9.08e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.67  E-value: 9.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   223 EKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKALVHQSDAVMDQIKKENEHYRLQVRELTDLLKAKDEEDdpvMMAVNAK 302
Cdd:TIGR02169  219 EKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEE---QLRVKEK 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   303 VEEWKLILSSKDDEIIEYQQMLQSLRGKLKNAQLDADKSnimalkqgiqerDSQIKMLTEQVEQYTKEMEKNTFIIEDLK 382
Cdd:TIGR02169  296 IGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL------------LAEIEELEREIEEERKRRDKLTEEYAELK 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   383 NElqkdkgtsnfyqqthYMKIHSKVQILEEKTKEA-ERIAELAEA--DAREKDKELVEALKRLKDYESGVYG-LEDAVIE 458
Cdd:TIGR02169  364 EE---------------LEDLRAELEEVDKEFAETrDELKDYREKleKLKREINELKRELDRLQEELQRLSEeLADLNAA 428

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 568967308   459 IKNCKAQIKIRDGEMEVLTKEINKLEMKINDILDENEALRER 500
Cdd:TIGR02169  429 IAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE 470
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 108-679 9.60e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 44.63  E-value: 9.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   108 RDTRFLRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENENSKLRRENEQLRQDIIDYQKQIDSQKESL 187
Cdd:TIGR04523  103 SDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEK 182

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   188 LSRRGEDSDYRSQLSKKNYEL---VQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKALVHQSDAVM 264
Cdd:TIGR04523  183 LNIQKNIDKIKNKLLKLELLLsnlKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQ 262

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   265 DQIKKENEHYRLQVRELTDLLKAKDEEDDPVMMAV----NAKVEEWKLILSSKDDEIIEYQQMLQSlrgklknaQLDADK 340
Cdd:TIGR04523  263 NKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEIsdlnNQKEQDWNKELKSELKNQEKKLEEIQN--------QISQNN 334

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   341 SNIMALKQGIQERDSQIKMLTEQVEQYTKEMEKNTFIIEDLKNELQKDKGTSNfyqqthymKIHSKVQILEEKTKEAERI 420
Cdd:TIGR04523  335 KIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIK--------NLESQINDLESKIQNQEKL 406

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   421 AELAEADAREKDKELVEALKRLKDYESGVYGLEDAVIEIKNCKAQIKIRDGEMEVLTKEINK----LEMKINDILDENEA 496
Cdd:TIGR04523  407 NQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETqlkvLSRSINKIKQNLEQ 486

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   497 LRERAGLEPKTMIDLTEFRNSKRLKQQQYRAENQVLLKEIESLEEERLDLKRKIRQMAQERGKRNaaSGLTIDDLNlSET 576
Cdd:TIGR04523  487 KQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDD--FELKKENLE-KEI 563

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   577 FSHENKIEGRKLNFMSLnnmnetQSKNETIVQDLPIQEEQSRNAELELDHQRSQAEQnefLSRELAEKEKDLERSRTVIA 656
Cdd:TIGR04523  564 DEKNKEIEELKQTQKSL------KKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISS---LEKELEKAKKENEKLSSIIK 634

                          570       580
                   ....*....|....*....|...
gi 568967308   657 KFQSKLKELVEENKQLEEGMKEI 679
Cdd:TIGR04523  635 NIKSKKNKLKQEVKQIKETIKEI 657
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 119-875 1.16e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.34  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   119 QLEKQLEQKDRELEDMEKELDKEkkvneqlalrNEEAENENSKLRRENEQLRQDIIDYQKQIDSQKESLLSRRGEDSDYR 198
Cdd:pfam15921   75 HIERVLEEYSHQVKDLQRRLNES----------NELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLR 144

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   199 SQLSKKNYEL--VQYLDEiQTLTEANEKIEvQNQEMRKNLEESVQEMEKMtdeynrmkaLVHQSDAVMDQIKKENEHYRL 276
Cdd:pfam15921  145 NQLQNTVHELeaAKCLKE-DMLEDSNTQIE-QLRKMMLSHEGVLQEIRSI---------LVDFEEASGKKIYEHDSMSTM 213

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   277 QVRELTDllkakdeeddpvmmAVNAKVEEWKLILSSKDDEIIEYQQMLQSLRGKLKNAQLDADKSNIMALKQGIQERDSQ 356
Cdd:pfam15921  214 HFRSLGS--------------AISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVE 279

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   357 IKMLTEQVEQYTKEMEKntfiIEDLKNELQKDKGTSNFYQQTHYMKIHSKVQILEEKTKEAERiaeLAEADAREKDKELV 436
Cdd:pfam15921  280 ITGLTEKASSARSQANS----IQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKR---MYEDKIEELEKQLV 352

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   437 EALKRLKdyesgvygleDAVIEIKNCKAQIKIRDGEMEVLTKEINKLEMKINDILDENEALRERAGLEPKTMIDLTEFRN 516
Cdd:pfam15921  353 LANSELT----------EARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELD 422

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   517 SKRLKQQQYRAenqvLLKEIESLEEERLDlkrkiRQMAQERGKRNAASGLTIDDLNLSETFSHENK-IEGRKLNFMSLNN 595
Cdd:pfam15921  423 DRNMEVQRLEA----LLKAMKSECQGQME-----RQMAAIQGKNESLEKVSSLTAQLESTKEMLRKvVEELTAKKMTLES 493

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   596 MNETQSKNETIVQ--------------------DLPIQEEQsrNAELELDHQRSQAEQNEFLSRELAEKEKDLERSRTVI 655
Cdd:pfam15921  494 SERTVSDLTASLQekeraieatnaeitklrsrvDLKLQELQ--HLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQI 571

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   656 AKFQSKLKE-------LVEENKQLEEGMKEILQAIKDMPKDSDVKGGEtsliIPSLERLVNAMESKNAEGIFDASLHLKA 728
Cdd:pfam15921  572 ENMTQLVGQhgrtagaMQVEKAQLEKEINDRRLELQEFKILKDKKDAK----IRELEARVSDLELEKVKLVNAGSERLRA 647

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   729 qVDQLTGRNEELRQELRQSRKEAVNYSQ--QLVKANL--KIDHLEKETDLLR---QSAGSNV-----VYKGIDLPDGIAP 796
Cdd:pfam15921  648 -VKDIKQERDQLLNEVKTSRNELNSLSEdyEVLKRNFrnKSEEMETTTNKLKmqlKSAQSELeqtrnTLKSMEGSDGHAM 726

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   797 SSAYIINSQneyLIHLLQELDNKEKKLKHLEDSLEDYNRKFAVIRHQQSLLYKEY---LSEKDIWKTDSEMIREEKRKLE 873
Cdd:pfam15921  727 KVAMGMQKQ---ITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELstvATEKNKMAGELEVLRSQERRLK 803


                   ..
gi 568967308   874 DQ 875
Cdd:pfam15921  804 EK 805
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1748-2412 1.43e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.86  E-value: 1.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1748 MRNLVDRLKSQLALKEKQQKALSRALLELRSEMTAAAEEriIAVTSQKEANLNVQQVVErhtrelKSQIEDLNENLLKLK 1827
Cdd:TIGR04523   38 LEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNK--IKILEQQIKDLNDKLKKN------KDKINKLNSDLSKIN 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1828 EALKTSKNKENSLADDLNELNNELQKKQKAYNKIL----REKDGIDQENDELRRQIKRLSSGLQSKTLIDNKQSLIDELQ 1903
Cdd:TIGR04523  110 SEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLteikKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNI 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1904 KKVKKLESQLERKVDDVDIKPVKEKSSKEELIRWEEGKKWQTK-VEGLRNRLKEKEGEAHGLAKQLNTLKELFAKADKEK 1982
Cdd:TIGR04523  190 DKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDnIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQL 269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1983 LTLQKKLKTTGMTVDQvlgvralesekeleeLKKKNLDLENDILYMRTQQAlprDSVVEDLHLQNKYLQEKLHTLEKKLS 2062
Cdd:TIGR04523  270 SEKQKELEQNNKKIKE---------------LEKQLNQLKSEISDLNNQKE---QDWNKELKSELKNQEKKLEEIQNQIS 331

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2063 K-EKYSQSLTSEIESddhcqkeqeLQKENLKLSSENIELKFQLEQANKDLPRLKNQVKDLKEMCEFLKKGKLELERKLGQ 2141
Cdd:TIGR04523  332 QnNKIISQLNEQISQ---------LKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQN 402

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2142 VRgagrsgKTIPELEKTIGLMKKVVEKVQRENEQLkKASGILTSEKMATIEEENRNLKAELEKLKAhFGRQLSMQFESKN 2221
Cdd:TIGR04523  403 QE------KLNQQKDEQIKKLQQEKELLEKEIERL-KETIIKNNSEIKDLTNQDSVKELIIKNLDN-TRESLETQLKVLS 474

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2222 KGTEKIVAENERLRKELKKEIEASEKLRIAKNNLELVNDKMAAQLEETGKRLQFAESRAPQLEgADSKSWKSIVVSRVYE 2301
Cdd:TIGR04523  475 RSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKE-SKISDLEDELNKDDFE 553

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2302 TKMKELESDIAKKNQSITDLKQ----LVREATEREQKAKKYTED-------LEQQIEILKNVPEGAETEQELIRELQLLR 2370
Cdd:TIGR04523  554 LKKENLEKEIDEKNKEIEELKQtqksLKKKQEEKQELIDQKEKEkkdlikeIEEKEKKISSLEKELEKAKKENEKLSSII 633

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....
gi 568967308  2371 LANNQMDKERAELIHQIEINKDQTRADSSIPDSD--QLKEKIND 2412
Cdd:TIGR04523  634 KNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKikESKTKIDD 677
PTZ00121 PTZ00121
MAEBL; Provisional
 814-1398 1.44e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 1.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  814 QELDNKEKKLKHLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKDIWKTDSEMIREEKRKLED--QAEQDAVKVKEYNNLLS 891
Cdd:PTZ00121 1246 EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEakKKAEEAKKADEAKKKAE 1325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  892 ALQMDSNEMKKMLSENSRKITVLQVNEKSLIRQYTTLVEMER--HLRKENGKHRNDVIAMEAEVTEKLGSLQRFKEMAIF 969
Cdd:PTZ00121 1326 EAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEaaEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKK 1405

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  970 KIAALQKVidnsvslselELANKQYNELTTKYRDILQKDnmlvqrtsnlehlecenaSLKEQMEAISKELEItKEKLHTI 1049
Cdd:PTZ00121 1406 KADELKKA----------AAAKKKADEAKKKAEEKKKAD------------------EAKKKAEEAKKADEA-KKKAEEA 1456

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1050 EQAWEQETKLGNDSNMDKAKKSMTNSDIVSISKKITVLEMKELNERQRAEHCQKMYEHLRTSlkqmEERNFELETKFTEL 1129
Cdd:PTZ00121 1457 KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA----EEAKKADEAKKAEE 1532

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1130 TKINLDAQKVEQMLRdelADSVTKAVsdadrqrilELEKSEVELKVE-VSKLREISDIAKRQVDFLNSQQQSREKEVESL 1208
Cdd:PTZ00121 1533 AKKADEAKKAEEKKK---ADELKKAE---------ELKKAEEKKKAEeAKKAEEDKNMALRKAEEAKKAEEARIEEVMKL 1600

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1209 RTQLLDFQAQSDEKALIAKLHQHVVSLQISEATALGKLESVTSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHL 1288
Cdd:PTZ00121 1601 YEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEA 1680

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1289 RQTIQSLRRQFSGALPLAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRnmeNKTLELELKLKGLEELISTLKDARGAQK 1368
Cdd:PTZ00121 1681 KKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENK---IKAEEAKKEAEEDKKKAEEAKKDEEEKK 1757

                         570       580       590
                  ....*....|....*....|....*....|
gi 568967308 1369 VINWHVKIEELRLQELKLNRELVKgKEEIK 1398
Cdd:PTZ00121 1758 KIAHLKKEEEKKAEEIRKEKEAVI-EEELD 1786
PRK03992 PRK03992
proteasome-activating nucleotidase; Provisional
 130-173 1.59e-03

proteasome-activating nucleotidase; Provisional


Pssm-ID: 179699 [Multi-domain]  Cd Length: 389  Bit Score: 43.28  E-value: 1.59e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 568967308  130 ELEDMEKELDKEKKVNEQLALRNEEAENENSKLRRENEQLRQDI 173
Cdd:PRK03992    2 RLEALEERNSELEEQIRQLELKLRDLEAENEKLERELERLKSEL 45
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1482-2248 1.65e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 43.81  E-value: 1.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1482 LRKIKENIQVILKTQATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATADREKLIAELERKELEPKSHHTMK 1561
Cdd:pfam02463  271 LKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIK 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1562 IAHQTIANMQARLNHKEEVLKKYQHLLEKAREEQREIVKKHEEDLHVLHHKLEQQADNSLNKFRQTAQDLLKqspapvpt 1641
Cdd:pfam02463  351 REAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLK-------- 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1642 nkhfIRLAEMEQTVAEQDDSLSSLLTKLKKVSKDLEKQKEITELKVREFENTKLRLQETHASEVKKVKAEvEDLRHALAQ 1721
Cdd:pfam02463  423 ----EEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLEL-LLSRQKLEE 497

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1722 AHKDSQSLKSELQAQKEANSRAPTTTMRNLVDRLKSQLALKEKQQKALSRALLELRSEMTAAAEERIIAVTSQKEANLNV 1801
Cdd:pfam02463  498 RSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGA 577

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1802 QQVVERHTRELKSQIEDLNENLLKLKEALKTSKNKENSLADDLNELNNELQKKQKAYNKILREKDGIDQENDELRRQIKR 1881
Cdd:pfam02463  578 RKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEG 657

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1882 LSSGLQSKTLIDNKQSLIDELQKKVKKLESQLERKVddvdIKPVKEKSSKEELIRWEEGKKWQTKVEGLRNRLKEKEGEA 1961
Cdd:pfam02463  658 LAEKSEVKASLSELTKELLEIQELQEKAESELAKEE----ILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDK 733

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1962 HGLAKQLNTLKELFAKADKEKLTLQKKLKTTGMTVDQVLGVRALESEKELEELKKKNLDLENDILYMRTQQALPRDSVVE 2041
Cdd:pfam02463  734 INEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEE 813

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2042 DLHLQNKYLQEKLHTLEKKLSKEKYSQSLTSEIESDDHCQKEQELQKENLKLSSENIELKFQLEQANKDLPRLKNQVKDL 2121
Cdd:pfam02463  814 AELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEE 893

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  2122 KEmcEFLKKGKLELERKLGQVRgagrsgKTIPELEKTIGLMKKVVEKVQRENEQLKKAsGILTSEKMATIEEENRNLKAE 2201
Cdd:pfam02463  894 KE--KEEKKELEEESQKLNLLE------EKENEIEERIKEEAEILLKYEEEPEELLLE-EADEKEKEENNKEEEEERNKR 964

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 568967308  2202 LEKLKAHFGRQLSM---QFESKNKGTEKIVAENERLRKELKKEIEASEKL 2248
Cdd:pfam02463  965 LLLAKEELGKVNLMaieEFEEKEERYNKDELEKERLEEEKKKLIRAIIEE 1014
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 85-689 1.77e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.90  E-value: 1.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308    85 NQLKTKVMKLENELEMAQqsaggRDTRFLRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENENSKLRR 164
Cdd:TIGR02169  290 LRVKEKIGELEAEIASLE-----RSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKE 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   165 ENEQLRQDIIDYQKQIDSQKESLLSRRGEDSDYRSQLSKKNYELVQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEME 244
Cdd:TIGR02169  365 ELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKE 444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   245 KMTDEYNRMKALVHQSDAVMDQIKKENEHYRLQVRELTDLLKAKDEEDDPVMMAVNAKVEEWK------LILSSKDDEII 318
Cdd:TIGR02169  445 DKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRggraveEVLKASIQGVH 524

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   319 -----------EYQQMLQSLRG-KLKNAQLDAD---KSNIMALKQGIQERDSQIKMLTEQVEQYTKEMEKNTFIIEDLKN 383
Cdd:TIGR02169  525 gtvaqlgsvgeRYATAIEVAAGnRLNNVVVEDDavaKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVD 604

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   384 ELQKDKGtsnfYQQTHYMKIHSKVqiLEEKTKEAERIAELA-----EADAREKDKELVEALKRLKDYESGVYGLEDAVIE 458
Cdd:TIGR02169  605 LVEFDPK----YEPAFKYVFGDTL--VVEDIEAARRLMGKYrmvtlEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQR 678

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   459 IKnckAQIKIRDGEMEVLTKEINKLEMKINDILDENEALRERAGLEPKTMIDLTEFRNSKRLKQQQYRAENQVLLKEIES 538
Cdd:TIGR02169  679 LR---ERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEN 755

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   539 LEEERLDLKRKIRQMAQERGKRNAAsgltIDDLNLSETFSHENKIEGrklnfmSLNNMNETQSKNETIVQDLPiQEEQSR 618
Cdd:TIGR02169  756 VKSELKELEARIEELEEDLHKLEEA----LNDLEARLSHSRIPEIQA------ELSKLEEEVSRIEARLREIE-QKLNRL 824

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568967308   619 NAELELDHQRSQAEQNEFLSREL--AEKEKDLERSRTVIAKFQSKLKELVEENKQLEEGMKEILQAIKDMPKD 689
Cdd:TIGR02169  825 TLEKEYLEKEIQELQEQRIDLKEqiKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQ 897
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 52-252 1.94e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 43.48  E-value: 1.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308    52 FRITQSLMKMKAQEVELALEEVEKAGEEQAKFENQ-----LKTKVMKLENELEMAQQsaggrDTRFLRDEIRQLEKQLEQ 126
Cdd:pfam05667  300 FTHTEKLQFTNEAPAATSSPPTKVETEEELQQQREeeleeLQEQLEDLESSIQELEK-----EIKKLESSIKQVEEELEE 374

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   127 KDRELEDMEKELDKEKKVNEQLalrnEEAENENSKLRRENEQLRQDIIDYQKQIDSQKESLLSrrgEDSDYRSQLSKKNY 206
Cdd:pfam05667  375 LKEQNEELEKQYKVKKKTLDLL----PDAEENIAKLQALVDASAQRLVELAGQWEKHRVPLIE---EYRALKEAKSNKED 447

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 568967308   207 ELVQYLDEIQTLteaNEKIEVQNQEMRKNLEESVQ---EMEKMTDEYNR 252
Cdd:pfam05667  448 ESQRKLEEIKEL---REKIKEVAEEAKQKEELYKQlvaEYERLPKDVSR 493
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1756-1919 1.94e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1756 KSQLALKEKQQKALSRALLELRSEMTAAAEERIiAVTSQKEANLNVQQV---------VERHTRELKSQIEDLNENLLKL 1826
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAELD-ALQERREALQRLAEYswdeidvasAEREIAELEAELERLDASSDDL 687

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1827 KEalktsknkensLADDLNELNNELQKKQKAYNKILREKDGIDQENDELRRQIKRLSSGLQS------------------ 1888
Cdd:COG4913   688 AA-----------LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaedlarlelralleerfa 756

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 568967308 1889 --------KTLIDNKQSLIDELQKKVKKLESQLERKVDD 1919
Cdd:COG4913   757 aalgdaveRELRENLEERIDALRARLNRAEEELERAMRA 795
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1764-1993 2.11e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1764 KQQKALSRALLELRSEMtaAAEERIIAVTSQKEANLNVQqvverhTRELKSQIEDLNENLLKLKEALKTSKNKENSLADD 1843
Cdd:COG4942    20 DAAAEAEAELEQLQQEI--AELEKELAALKKEEKALLKQ------LAALERRIAALARRIRALEQELAALEAELAELEKE 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1844 LNELNNELQKKQKAYNKILREKDGIDQEN--------DELRRQIKRLSSglqSKTLIDNKQSLIDELQKKVKKLESQLER 1915
Cdd:COG4942    92 IAELRAELEAQKEELAELLRALYRLGRQPplalllspEDFLDAVRRLQY---LKYLAPARREQAEELRADLAELAALRAE 168

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568967308 1916 KVDDVDIKPVKEKSSKEELIRWEEGKKWQTK-VEGLRNRLKEKEGEAHGLAKQLNTLKELFAKADKEKLTLQKKLKTTG 1993
Cdd:COG4942   169 LEAERAELEALLAELEEERAALEALKAERQKlLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 120-491 2.74e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.09  E-value: 2.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   120 LEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENENSKLRRENEQLRQDIIDYQKQ---IDSQKESLLSRRGEDSD 196
Cdd:TIGR04523  361 KQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEkelLEKEIERLKETIIKNNS 440

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   197 YRSQLSKKNYELVQYLDEIQTLTEANEK----IEVQNQEMRKNLEESVQEMEKMTDEYNRMKALVHQSDAVMDQIKKENE 272
Cdd:TIGR04523  441 EIKDLTNQDSVKELIIKNLDNTRESLETqlkvLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKIS 520

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   273 HYRLQVRELTDL-----LKAKDEEDDPVMMAVNAKVEEWKLILSSKDDEIIEYQQMLQSLRGKLKNAQLDADK--SNIMA 345
Cdd:TIGR04523  521 SLKEKIEKLESEkkekeSKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQkeKEKKD 600

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   346 LKQGIQERDSQIKMLTEQVEQYTKEMEKNTFIIEDLKNELQKDKGTSNFYQQTHYMKIHSKVQILEEKTKEAERIAELAE 425
Cdd:TIGR04523  601 LIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIE 680

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568967308   426 ADAREKDKELVEALKRLKDyESGVYGLEDAVIEIKNCKAQIKIRDGEMEVLTKEINKLEMKINDIL 491
Cdd:TIGR04523  681 LMKDWLKELSLHYKKYITR-MIRIKDLPKLEEKYKEIEKELKKLDEFSKELENIIKNFNKKFDDAF 745
COG4026 COG4026
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General ...
 82-191 2.95e-03

Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General function prediction only];


Pssm-ID: 443204 [Multi-domain]  Cd Length: 287  Bit Score: 42.02  E-value: 2.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   82 KFENQLKTKV-----MKL--------------ENELEMAQQSAGGRDTRFLRdEIRQLEKQLEQKDRELEDMEKELDKEK 142
Cdd:COG4026    77 KFFEELKGMVghverMKLplghdveyvdvelvRKEIKNAIIRAGLKSLQNIP-EYNELREELLELKEKIDEIAKEKEKLT 155

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 568967308  143 KVNEQLALRNEEAENENSKLRRENEQLRQD---IIDYQKQIDSQKESLLSRR 191
Cdd:COG4026   156 KENEELESELEELREEYKKLREENSILEEEfdnIKSEYSDLKSRFEELLKKR 207
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
94-284 3.51e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.70  E-value: 3.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   94 LENELEMAQQSAGGRdTRFLRDEIRQLEKQLEQKDRELEDMEKE-----LDKEKKVNEQlalRNEEAENENSKLRRENEQ 168
Cdd:COG3206   162 LEQNLELRREEARKA-LEFLEEQLPELRKELEEAEAALEEFRQKnglvdLSEEAKLLLQ---QLSELESQLAEARAELAE 237

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  169 LRQDIIDYQKQIDSQKESL--LSRRGEDSDYRSQLSKKNYELVQ----YLDEIQTLTEANEKIEVQNQEMRKNLEESVQE 242
Cdd:COG3206   238 AEARLAALRAQLGSGPDALpeLLQSPVIQQLRAQLAELEAELAElsarYTPNHPDVIALRAQIAALRAQLQQEAQRILAS 317

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 568967308  243 MEKmtdEYNRMKALVHQSDAVMDQIKKENEHYRLQVRELTDL 284
Cdd:COG3206   318 LEA---ELEALQAREASLQAQLAQLEARLAELPELEAELRRL 356
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1677-1860 3.94e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 3.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1677 EKQKEITELKvrefenTKLRLQETHASEVKKVKAEVEDLRHAL-------------AQAHKDSQSLKSELQAQKEANSRa 1743
Cdd:COG4913   614 ALEAELAELE------EELAEAEERLEALEAELDALQERREALqrlaeyswdeidvASAEREIAELEAELERLDASSDD- 686

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1744 ptttmrnlVDRLKSQLALKEKQQKALSRALLELRSEMTAAAEERIIAVTSQKEANLNVQQVVERHTRELKSQIEDLNENL 1823
Cdd:COG4913   687 --------LAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAA 758

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 568967308 1824 LKLKEALKTSKNKENSLAD---DLNELNNELQKKQKAYNK 1860
Cdd:COG4913   759 LGDAVERELRENLEERIDAlraRLNRAEEELERAMRAFNR 798
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 624-1444 4.04e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.74  E-value: 4.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   624 LDHQRSQAEQNEFLSRELAEKEK-----DLERSRTVIAKFQSKLKELVEENKQLEEGMKEILQAIKdmpkdsdvkggETS 698
Cdd:TIGR02168  205 LERQAEKAERYKELKAELRELELallvlRLEELREELEELQEELKEAEEELEELTAELQELEEKLE-----------ELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   699 LIIPSLERLVNAMESKNAEgifdaslhLKAQVDQLTGRNEELRQELRQSRKEAVNYSQQLVKANLKIDHLEKETDLLRQS 778
Cdd:TIGR02168  274 LEVSELEEEIEELQKELYA--------LANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEK 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   779 AGSnvvykgidlpdgiapsSAYIINSQNEYLIHLLQELDNKEKKLKHLEDSLEDYNRKFAVIRHQQSLLykeylsEKDIW 858
Cdd:TIGR02168  346 LEE----------------LKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL------NNEIE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   859 KTDSEMIREEKRKLEDQAEQDAVKVKEYNNLLSALQMDSNEMKKMLSENSRKITVLQVNEKSLIRQYTTLVEMERHLRKE 938
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERE 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   939 NGKHRNDVIAMEAEVTEKLGSLQRFKE--MAIFKIAALQKVIDNSVSL-SELELA-------NKQY---NELTTKYRDI- 1004
Cdd:TIGR02168  484 LAQLQARLDSLERLQENLEGFSEGVKAllKNQSGLSGILGVLSELISVdEGYEAAieaalggRLQAvvvENLNAAKKAIa 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1005 ------LQKDNMLVQRTSNLEHLECENASLKEQME---AISKELEITKEKLHTIEQAWEQETKLGND--SNMDKAKKSMT 1073
Cdd:TIGR02168  564 flkqneLGRVTFLPLDSIKGTEIQGNDREILKNIEgflGVAKDLVKFDPKLRKALSYLLGGVLVVDDldNALELAKKLRP 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1074 NSDIVS-----------ISKKITVLEMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELETKFTELTKINLDAQKVEQM 1142
Cdd:TIGR02168  644 GYRIVTldgdlvrpggvITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1143 LRDELADsvTKAVSDADRQRILELEKSEVELKVEVSKLREISDIAKRQVDFLNSQQQSREKEVESLRTQLLDFQAQ-SDE 1221
Cdd:TIGR02168  724 LSRQISA--LRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEElKAL 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1222 KALIAKLHQHVVSLQISEATALGKLESVTSKLQKMEAYNLRLEQKLDEKEQALyyarlegrNRAKHLRQTIQSLRRQFSG 1301
Cdd:TIGR02168  802 REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDI--------ESLAAEIEELEELIEELES 873

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1302 ALplaqqEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKtlelelklkgleelistLKDARGAQKVINWHVKIEELRL 1381
Cdd:TIGR02168  874 EL-----EALLNERASLEEALALLRSELEELSEELRELESK-----------------RSELRRELEELREKLAQLELRL 931

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568967308  1382 QELKLNRELVKGKeeikylnnIISEYEHTinslEEEIVQQSKFHEERQMAWDQREVELERQLD 1444
Cdd:TIGR02168  932 EGLEVRIDNLQER--------LSEEYSLT----LEEAEALENKIEDDEEEARRRLKRLENKIK 982
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1786-1997 4.82e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.12  E-value: 4.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1786 ERIIAVTSQKEANLNVQqvvERHTRELKSQIEDLNENLLKLKEALKtsknkensladdlNELNNELQKKQKAYNKILRE- 1864
Cdd:PRK00409  519 NELIASLEELERELEQK---AEEAEALLKEAEKLKEELEEKKEKLQ-------------EEEDKLLEEAEKEAQQAIKEa 582

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1865 KDGIDQENDELRRQIKRLSSGLQSKTLIDNKQSLIDELQKKVKKL----ESQLERKV-DDVDIKPVKEKSskeELIRWEE 1939
Cdd:PRK00409  583 KKEADEIIKELRQLQKGGYASVKAHELIEARKRLNKANEKKEKKKkkqkEKQEELKVgDEVKYLSLGQKG---EVLSIPD 659

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 568967308 1940 GKKWQTKVEGLRNRLKEKEGEAHGLAKqlntlKELFAKADKEKLtlqkKLKTTGMTVD 1997
Cdd:PRK00409  660 DKEAIVQAGIMKMKVPLSDLEKIQKPK-----KKKKKKPKTVKP----KPRTVSLELD 708
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 78-183 4.91e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 42.35  E-value: 4.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   78 EEQAKFEnQLKTKVMKLE---NELEMAQQSAGGRD--TRfLRDEIrqLEKQLEQKDRELEDMEKELDKEKKVNEQLALRN 152
Cdd:PRK10929  170 LAQAQLT-ALQAESAALKalvDELELAQLSANNRQelAR-LRSEL--AKKRSQQLDAYLQALRNQLNSQRQREAERALES 245

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 568967308  153 EEAENENS-----------KLRRE-----NEQL-RQDIIDY-QKQIDSQ 183
Cdd:PRK10929  246 TELLAEQSgdlpksivaqfKINRElsqalNQQAqRMDLIASqQRQAASQ 294
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1648-1897 4.94e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.74  E-value: 4.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1648 LAEMEQTVAEQDDSLSSLLTKLKKVSKDLEK-QKEITELkvrefentklrlqethASEVKKVKAEVEDLRHALAQAHKDS 1726
Cdd:COG3883     4 LALAAPTPAFADPQIQAKQKELSELQAELEAaQAELDAL----------------QAELEELNEEYNELQAELEALQAEI 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1727 QSLKSELQAQKEAnsraptttMRNLVDRLKSQLALKEKQQKALSRALLELRSEMTAAAEERIIAVTSQKEANLNVqqvve 1806
Cdd:COG3883    68 DKLQAEIAEAEAE--------IEERREELGERARALYRSGGSVSYLDVLLGSESFSDFLDRLSALSKIADADADL----- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308 1807 rhTRELKSQIEDLNENLLKLKEALKTSKNKENSLADDLNELNNELQKKQKAYNKILREKDGIDQENDELRRQIKRLSSGL 1886
Cdd:COG3883   135 --LEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAA 212

                         250
                  ....*....|.
gi 568967308 1887 QSKTLIDNKQS 1897
Cdd:COG3883   213 AAAAAAAAAAA 223
PTZ00121 PTZ00121
MAEBL; Provisional
 78-750 5.48e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 5.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   78 EEQAKFENQLKTKVMKLENELEMAQQSAGGRDTRFLRDEIRQLEKQLEQKDRELEDmEKELDKEKKVNE----QLALRNE 153
Cdd:PTZ00121 1095 EAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAED-AKRVEIARKAEDarkaEEARKAE 1173

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  154 EAENENSKLR----RENEQLRQdiIDYQKQIDSQKESLLSRRGEDSdyRSQLSKKNYELVQYLDEIQTLTEANEKIEvqn 229
Cdd:PTZ00121 1174 DAKKAEAARKaeevRKAEELRK--AEDARKAEAARKAEEERKAEEA--RKAEDAKKAEAVKKAEEAKKDAEEAKKAE--- 1246

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  230 qEMRKNLEESVQEMEKMTDEYNRMKALVHQSDAVMDQIKKENEHYRL-------QVRELTDLLKAKDEEDDPVMMAVNAK 302
Cdd:PTZ00121 1247 -EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKAdeakkaeEKKKADEAKKKAEEAKKADEAKKKAE 1325

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  303 VEEWKLILSSKDDEIIEYQQMLQSLRGKLKNAQLDADKSNIMALKQGIQERDSQIKMLTEQVEQYTKEMEKNTFIIEDLK 382
Cdd:PTZ00121 1326 EAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKK 1405

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  383 NELQKDKGTSNFYQQTHYMKIHSKVQILEEKTKEAERIAELAEADAREKDKELVEALKRLKDyesgvyglEDAVIEIKNC 462
Cdd:PTZ00121 1406 KADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAE--------EAKKADEAKK 1477

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  463 KAQIKIRDGEMEVLTKEINKLEMKINDILDENEALRERAGLEPKTMIDLTEFRNSKRLKQQQYRAENQVLLKEIESLEE- 541
Cdd:PTZ00121 1478 KAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEEl 1557

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  542 ERLDLKRKIRQMAQERGKRNAASgLTIDDLNLSEtfshENKIEGRKLNFMSLNNMNETQSKNEtivQDLPIQEEQSRNAE 621
Cdd:PTZ00121 1558 KKAEEKKKAEEAKKAEEDKNMAL-RKAEEAKKAE----EARIEEVMKLYEEEKKMKAEEAKKA---EEAKIKAEELKKAE 1629

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  622 lELDHQRSQAEQNEFLSRELAEKEKDLERSRTVIAKFQSKLKElvEENKQLEEGMKEilQAIKDMPKDSDVKGGETSLII 701
Cdd:PTZ00121 1630 -EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAE--EDKKKAEEAKKA--EEDEKKAAEALKKEAEEAKKA 1704

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....*....
gi 568967308  702 PSLERlVNAMESKNAEGIFDASLHLKAQVDQLTGRNEELRQELRQSRKE 750
Cdd:PTZ00121 1705 EELKK-KEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD 1752
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 614-938 6.06e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.23  E-value: 6.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  614 EEQSRNAE--LELDHQRSQAEQNEFLsRELAEKEKDLERSRTVIAKFQSKLKELVEENKQLEEGMKEILQAIKDMPKDSD 691
Cdd:COG1196   206 ERQAEKAEryRELKEELKELEAELLL-LKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE 284

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  692 VKGGETSLIIPSLERLVNAMEsknaegifdaslHLKAQVDQLTGRNEELRQELRQSRKEAVNYSQQLVKANLKIDHLEKE 771
Cdd:COG1196   285 EAQAEEYELLAELARLEQDIA------------RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEE 352

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  772 TDLLRQSagsnvvykgidlpdgiapssayiinsqneyLIHLLQELDNKEKKLKHLEDSLEDYNRKFAVIRHQQSLLYKEY 851
Cdd:COG1196   353 LEEAEAE------------------------------LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  852 LSEkdiwKTDSEMIREEKRKLEDQAEQDAVKVKEYNNLLSALQMDSNEMKKMLSENSRKITVLQVNEKSLIRQYTTLVEM 931
Cdd:COG1196   403 EEL----EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAA 478


                  ....*..
gi 568967308  932 ERHLRKE 938
Cdd:COG1196   479 LAELLEE 485
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 458-694 6.73e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 6.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  458 EIKNCKAQIKIRDGEMEVLTKEINKLEMKINDILDENEALRERaglepktMIDLTEFRNSKRLKQQQYRAENQVLLKEIE 537
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERR-------IAALARRIRALEQELAALEAELAELEKEIA 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  538 SLEEERLDLKRKIRQMAQERGKRNAASGLTIddLNLSETFSHENKiegrklNFMSLNNMNETQSKN-ETIVQDLPIQEEQ 616
Cdd:COG4942    94 ELRAELEAQKEELAELLRALYRLGRQPPLAL--LLSPEDFLDAVR------RLQYLKYLAPARREQaEELRADLAELAAL 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  617 SRNAELELDHQRS----QAEQNEFLSRELAEKEKDLERSRTVIAKFQSKLKELVEENKQLEEGMKEILQAIKDMPKDSDV 692
Cdd:COG4942   166 RAELEAERAELEAllaeLEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245


                  ..
gi 568967308  693 KG 694
Cdd:COG4942   246 AG 247
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 90-556 8.42e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 41.64  E-value: 8.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308    90 KVMKLENELEMAQQSAggRDTRFLRDEIRQ----LEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENENSKLRRE 165
Cdd:pfam15921  343 KIEELEKQLVLANSEL--TEARTERDQFSQesgnLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRE 420

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   166 NEQLRQDIidyqkqidSQKESLLsrrgedsdyRSQLSKKNYELVQYLDEIQTLTEANEKIevqnQEMRKNLEESVQEMEK 245
Cdd:pfam15921  421 LDDRNMEV--------QRLEALL---------KAMKSECQGQMERQMAAIQGKNESLEKV----SSLTAQLESTKEMLRK 479

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   246 MTDEYNRMKALVHQSDavmdqikkenehyrlqvRELTDlLKAKDEEDDPVMMAVNAKVEEwkliLSSKDDEIIEYQQMLQ 325
Cdd:pfam15921  480 VVEELTAKKMTLESSE-----------------RTVSD-LTASLQEKERAIEATNAEITK----LRSRVDLKLQELQHLK 537

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   326 SLRGKLKNAQLDADksnimALKQGIQERDSQIKMLTEQVEQYTK---EMEKNTFIIEDLKNELQKDKGTSNFYQQthymk 402
Cdd:pfam15921  538 NEGDHLRNVQTECE-----ALKLQMAEKDKVIEILRQQIENMTQlvgQHGRTAGAMQVEKAQLEKEINDRRLELQ----- 607

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   403 ihsKVQILEEKTKEAERIAELAEADAREKDKELVEA-LKRLKDYESGVYGLEDAVIEIKNCKAQIKIRDGEMEVLTKEI- 480
Cdd:pfam15921  608 ---EFKILKDKKDAKIRELEARVSDLELEKVKLVNAgSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFr 684

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   481 ----------NKLEMKINDILDENEALRERA-------GLEPKTMIDLTEFRNSKRLKQQQYRAENQVLLKEIESLEEER 543
Cdd:pfam15921  685 nkseemetttNKLKMQLKSAQSELEQTRNTLksmegsdGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEK 764

                          490
                   ....*....|...
gi 568967308   544 LDLKRKIRQMAQE 556
Cdd:pfam15921  765 HFLKEEKNKLSQE 777
PRK12704 PRK12704
phosphodiesterase; Provisional
 86-189 8.48e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 8.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   86 QLKTKVMKLENELEmaqqsaggRDTRFLRDEIRQLEKQLEQKDRELEDMEKELDKekkvneqlalRNEEAENENSKLRRE 165
Cdd:PRK12704   61 EAKEEIHKLRNEFE--------KELRERRNELQKLEKRLLQKEENLDRKLELLEK----------REEELEKKEKELEQK 122

                          90       100
                  ....*....|....*....|....
gi 568967308  166 NEQLRQDIIDYQKQIDSQKESLLS 189
Cdd:PRK12704  123 QQELEKKEEELEELIEEQLQELER 146
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 575-1257 8.49e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 41.64  E-value: 8.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   575 ETFSHENKIEGRKLNfmSLNNMNETQS---KNETIVQDLPIQEEQ-SRNAELELDHQRSQAEQNefLSRELAEKEKDLER 650
Cdd:pfam15921   81 EEYSHQVKDLQRRLN--ESNELHEKQKfylRQSVIDLQTKLQEMQmERDAMADIRRRESQSQED--LRNQLQNTVHELEA 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   651 SRTVIAKFQSKLKELVEENKQLEEGMKEILQAIKDMPKDSDVKGGETsliIPSLERLVNAMESKNAEGIFDASLHLKAQV 730
Cdd:pfam15921  157 AKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKK---IYEHDSMSTMHFRSLGSAISKILRELDTEI 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   731 DQLTGRNEELRQELRQSRKEAVNYSQQLVKANL-KIDHLEKE-----TDLLRQSAGSNVVYKGIDLPDGIAPSSAyiiNS 804
Cdd:pfam15921  234 SYLKGRIFPVEDQLEALKSESQNKIELLLQQHQdRIEQLISEheveiTGLTEKASSARSQANSIQSQLEIIQEQA---RN 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   805 QNEYLIHLLQELDNKEKKLK-HLEDSLEDYNRKFAVIRHQQSLLYKEyLSEKdiwKTDSEMIREEKRKLEDQ-------- 875
Cdd:pfam15921  311 QNSMYMRQLSDLESTVSQLRsELREAKRMYEDKIEELEKQLVLANSE-LTEA---RTERDQFSQESGNLDDQlqklladl 386

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   876 --AEQDAVKVKEYNNLLSALQMDS----NEMKKMLSENSRKITVLQVNEKSLIRQYTTlvEMERHLRKENGKhrNDVIAM 949
Cdd:pfam15921  387 hkREKELSLEKEQNKRLWDRDTGNsitiDHLRRELDDRNMEVQRLEALLKAMKSECQG--QMERQMAAIQGK--NESLEK 462

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   950 EAEVTEKLGSLQRFKEMAIFKIAALQKVIDNS--------VSLSELELANKQYNELTTKYRD----ILQKDNMLVQRTSN 1017
Cdd:pfam15921  463 VSSLTAQLESTKEMLRKVVEELTAKKMTLESSertvsdltASLQEKERAIEATNAEITKLRSrvdlKLQELQHLKNEGDH 542

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1018 LEHLECENASLKEQMEAISKELEITKEKLHTIEQAWEQETKLGNDSNMDKAKKSMTNSDivsisKKITVLEMKELNERQR 1097
Cdd:pfam15921  543 LRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEIND-----RRLELQEFKILKDKKD 617

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1098 AEhcqkmyehlrtsLKQMEERNFELETKFTELTKIN---LDAQKVEQMLRDELADSVTKAVSdadrqrilELEKSEVELK 1174
Cdd:pfam15921  618 AK------------IRELEARVSDLELEKVKLVNAGserLRAVKDIKQERDQLLNEVKTSRN--------ELNSLSEDYE 677

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  1175 VEVSKLREISDIAKRQVDFLNSQQQSREKEVESLRTQLLDFQAQSDEKALIAklhqhvVSLQISEATALGKLESVTSKLQ 1254
Cdd:pfam15921  678 VLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVA------MGMQKQITAKRGQIDALQSKIQ 751


                   ...
gi 568967308  1255 KME 1257
Cdd:pfam15921  752 FLE 754
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
78-563 9.15e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.59  E-value: 9.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   78 EEQAKFENQLKTKVMKLENELEMAQQ-SAGGRDTRFLRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLalrnEEAE 156
Cdd:PRK03918  269 EELKKEIEELEEKVKELKELKEKAEEyIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERL----EELK 344

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  157 NENSKLRRENEQLRQDIIDYQ--KQIDSQKESLLSRRGEdsdyrsqlskknyelvqyldeiqtltEANEKIEVQNQEMRK 234
Cdd:PRK03918  345 KKLKELEKRLEELEERHELYEeaKAKKEELERLKKRLTG--------------------------LTPEKLEKELEELEK 398

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  235 NLEESVQEMEKMTDEYNRMKALVHQSDAVMDQIKKENEHYRLQVRELTdllkakdEEDDPVMMavnakvEEWKLILSSKD 314
Cdd:PRK03918  399 AKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELT-------EEHRKELL------EEYTAELKRIE 465

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  315 DEIIEYQQMLQSLRGKLKNAQ-LDADKSNIMALKQGIQerdsQIKMLTEQVEQYTKE-MEKNTFIIEDLKNELQKDKGts 392
Cdd:PRK03918  466 KELKEIEEKERKLRKELRELEkVLKKESELIKLKELAE----QLKELEEKLKKYNLEeLEKKAEEYEKLKEKLIKLKG-- 539

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  393 nfyQQTHYMKIHSKVQILEEKTKEAERIAELAEADAREKDKELVE-ALKRLKDYESGVYGLEDA---VIEIKNCKAQIKI 468
Cdd:PRK03918  540 ---EIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEElGFESVEELEERLKELEPFyneYLELKDAEKELER 616

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308  469 RDGEMEVLTKEINKLEMKINDILDENEALRERAGlEPKTMIDLTEFRNsKRLKQQQYRAENQVLLKEIESLEEERLDLKR 548
Cdd:PRK03918  617 EEKELKKLEEELDKAFEELAETEKRLEELRKELE-ELEKKYSEEEYEE-LREEYLELSRELAGLRAELEELEKRREEIKK 694

                         490
                  ....*....|....*
gi 568967308  549 KIRQMAQERGKRNAA 563
Cdd:PRK03918  695 TLEKLKEELEEREKA 709
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 27-674 9.55e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 41.50  E-value: 9.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308    27 KLLISLSKVEVNELKNEDQENMIHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLENELEMAQQSAG 106
Cdd:pfam02463  233 KLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDD 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   107 GRDTRFLRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQlalrNEEAENENSKLRRENEQLRQDIIDYQKQIDSQKES 186
Cdd:pfam02463  313 EEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREA----EEEEEEELEKLQEKLEQLEEELLAKKKLESERLSS 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   187 LLSRRGEDSDYRSQLSKKNYELVQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKALVHQSDAVMDQ 266
Cdd:pfam02463  389 AAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELK 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   267 ---IKKENEHYRLQVRELTDLLKAKDEEDDPVMMAVNAKVEEWKLIL-----SSKDDEIIEYQQMLQSLRGKLKNAQLDA 338
Cdd:pfam02463  469 kseDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALikdgvGGRIISAHGRLGDLGVAVENYKVAISTA 548

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   339 DKSNIMALKQGIQERDSQIKMLTEQveqyTKEMEKNTFIIEDLKNELQKDKGTSNFYQQTHYMKIHSKVQILEEKTKEAE 418
Cdd:pfam02463  549 VIVEVSATADEVEERQKLVRALTEL----PLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKV 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   419 RIAELAEAD-AREKDKELVEALKRLKDYESGVYGLEDAVIEIKNCKAQIKIRDGEMEVLTKEINKLEMKINDILDENEAL 497
Cdd:pfam02463  625 VEGILKDTElTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKK 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   498 RERAGLEPKTMIDLTEFRNSKRLKQQQYRAENQVLLKEIESLEEERLDLKRKIRQMAQERGKRNAASGLTIDDLNLSETF 577
Cdd:pfam02463  705 EQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTE 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967308   578 SH---ENKIEGRKLNFMSLNNMNETQSKNETIVQDLPIQEEQSRNAELELDHQRSQAEQNEFLSRELAEKEKDLERSRTV 654
Cdd:pfam02463  785 KLkveEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEIT 864

                          650       660
                   ....*....|....*....|
gi 568967308   655 IAKFQSKLKELVEENKQLEE 674
Cdd:pfam02463  865 KEELLQELLLKEEELEEQKL 884
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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