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Conserved domains on  [gi|568959964|ref|XP_006510619|]
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endonuclease/exonuclease/phosphatase family domain-containing protein 1 isoform X3 [Mus musculus]

Protein Classification

ComEA family DNA-binding protein( domain architecture ID 11446237)

ComEA family DNA-binding protein contains a helix-hairpin-helix (HhH) motif

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ComEA COG1555
DNA uptake protein ComE or related DNA-binding protein [Replication, recombination and repair]; ...
 127-195 2.07e-23

DNA uptake protein ComE or related DNA-binding protein [Replication, recombination and repair];


:

Pssm-ID: 441164 [Multi-domain]  Cd Length: 72  Bit Score: 91.08  E-value: 2.07e-23
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568959964 127 LTTTVPLTPRVNINTATLAQLMSVRGLSEKMALSIVDYRREHGPFRSVEDLVRMDGINAAFLDRIRHQV 195
Cdd:COG1555    3 ASASAAAGGKVDINTATAEELQTLPGIGPKLAQRIVEYREKNGPFKSVEDLLEVKGIGPKTLEKLKPYL 71
ComEA COG1555
DNA uptake protein ComE or related DNA-binding protein [Replication, recombination and repair]; ...
 38-95 3.55e-22

DNA uptake protein ComE or related DNA-binding protein [Replication, recombination and repair];


:

Pssm-ID: 441164 [Multi-domain]  Cd Length: 72  Bit Score: 88.00  E-value: 3.55e-22
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 568959964  38 ERLNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVK 95
Cdd:COG1555   11 GKVDINTATAEELQTLPGIGPKLAQRIVEYREKNGPFKSVEDLLEVKGIGPKTLEKLK 68
 
Name Accession Description Interval E-value
ComEA COG1555
DNA uptake protein ComE or related DNA-binding protein [Replication, recombination and repair]; ...
 127-195 2.07e-23

DNA uptake protein ComE or related DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 441164 [Multi-domain]  Cd Length: 72  Bit Score: 91.08  E-value: 2.07e-23
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568959964 127 LTTTVPLTPRVNINTATLAQLMSVRGLSEKMALSIVDYRREHGPFRSVEDLVRMDGINAAFLDRIRHQV 195
Cdd:COG1555    3 ASASAAAGGKVDINTATAEELQTLPGIGPKLAQRIVEYREKNGPFKSVEDLLEVKGIGPKTLEKLKPYL 71
ComEA COG1555
DNA uptake protein ComE or related DNA-binding protein [Replication, recombination and repair]; ...
 38-95 3.55e-22

DNA uptake protein ComE or related DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 441164 [Multi-domain]  Cd Length: 72  Bit Score: 88.00  E-value: 3.55e-22
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 568959964  38 ERLNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVK 95
Cdd:COG1555   11 GKVDINTATAEELQTLPGIGPKLAQRIVEYREKNGPFKSVEDLLEVKGIGPKTLEKLK 68
HHH_3 pfam12836
Helix-hairpin-helix motif; The HhH domain is a short DNA-binding domain.
 37-95 1.31e-19

Helix-hairpin-helix motif; The HhH domain is a short DNA-binding domain.


Pssm-ID: 463723 [Multi-domain]  Cd Length: 62  Bit Score: 80.60  E-value: 1.31e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568959964   37 QERLNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVK 95
Cdd:pfam12836   1 AVGVDINTASAELLSRVPGLGPKLAKNIVEYREENGPFRSREDLLKVKGLGPKTFEQLA 59
HHH_3 pfam12836
Helix-hairpin-helix motif; The HhH domain is a short DNA-binding domain.
 136-195 7.96e-19

Helix-hairpin-helix motif; The HhH domain is a short DNA-binding domain.


Pssm-ID: 463723 [Multi-domain]  Cd Length: 62  Bit Score: 78.68  E-value: 7.96e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959964  136 RVNINTATLAQLMSVRGLSEKMALSIVDYRREHGPFRSVEDLVRMDGINAAFLDRIRHQV 195
Cdd:pfam12836   3 GVDINTASAELLSRVPGLGPKLAKNIVEYREENGPFRSREDLLKVKGLGPKTFEQLAGFL 62
comE TIGR01259
comEA protein; This model describes the ComEA protein in bacteria. The com E locus is ...
 40-100 7.35e-14

comEA protein; This model describes the ComEA protein in bacteria. The com E locus is obligatory for bacterial cell competence - the process of internalizing the exogenous added DNA. Lesions in the loci has been variously described for the appearance of competence-related pheonotypes and impairment of competence, suggesting their intimate functional role in bacterial transformation. [Cellular processes, DNA transformation]


Pssm-ID: 213597 [Multi-domain]  Cd Length: 120  Bit Score: 66.85  E-value: 7.35e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568959964   40 LNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICV 100
Cdd:TIGR01259  60 VNINAASLEELQALPGIGPAKAKAIIEYREENGAFKSVDDLTKVSGIGEKSLEKLKDYATV 120
comE TIGR01259
comEA protein; This model describes the ComEA protein in bacteria. The com E locus is ...
 137-195 2.69e-12

comEA protein; This model describes the ComEA protein in bacteria. The com E locus is obligatory for bacterial cell competence - the process of internalizing the exogenous added DNA. Lesions in the loci has been variously described for the appearance of competence-related pheonotypes and impairment of competence, suggesting their intimate functional role in bacterial transformation. [Cellular processes, DNA transformation]


Pssm-ID: 213597 [Multi-domain]  Cd Length: 120  Bit Score: 62.61  E-value: 2.69e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568959964  137 VNINTATLAQLMSVRGLSEKMALSIVDYRREHGPFRSVEDLVRMDGINAAFLDRIRHQV 195
Cdd:TIGR01259  60 VNINAASLEELQALPGIGPAKAKAIIEYREENGAFKSVDDLTKVSGIGEKSLEKLKDYA 118
dnaE2 PRK05672
error-prone DNA polymerase; Validated
 110-189 1.48e-04

error-prone DNA polymerase; Validated


Pssm-ID: 235553 [Multi-domain]  Cd Length: 1046  Bit Score: 43.31  E-value: 1.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959964  110 SPSSLrrdlLAEQQPHHLTTTVP----------LTPRVNINTATLAQLMSVRGLSEKMALSIVDyRREHGPFRSVEDLVR 179
Cdd:PRK05672  775 SPQQL----VQDARRHGVEVLPVdvnasgwdatLEPLPDGGPAVRLGLRLVRGLGEEAAERIVA-ARARGPFTSVEDLAR 849

                          90
                  ....*....|
gi 568959964  180 MDGINAAFLD 189
Cdd:PRK05672  850 RAGLDRRQLE 859
T2SS_GspK NF037980
type II secretion system minor pseudopilin GspK;
33-95 1.76e-04

type II secretion system minor pseudopilin GspK;


Pssm-ID: 468299 [Multi-domain]  Cd Length: 311  Bit Score: 42.66  E-value: 1.76e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568959964  33 ILVNQERLNINTATEEELMTL-PGVTRAVARSIVEYREYiGGFKKVEDLALVSGVGATKLEQVK 95
Cdd:NF037980 206 LPTTTLAINVNTAPAEVLAALaALLSLSQARALLAARPA-AGFRSVGDFLAQLALAGLALDASD 268
T2SS_GspK NF037980
type II secretion system minor pseudopilin GspK;
109-177 3.25e-04

type II secretion system minor pseudopilin GspK;


Pssm-ID: 468299 [Multi-domain]  Cd Length: 311  Bit Score: 41.89  E-value: 3.25e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568959964 109 HSPSSLRR------DLLAEQQPHhLTTTVPLTPRVNINTATLAQLMSVR-GLSEKMALSIVDyRREHGPFRSVEDL 177
Cdd:NF037980 180 ADVSELRLvpgvtpALYARLRPY-VCALPTTTLAINVNTAPAEVLAALAaLLSLSQARALLA-ARPAAGFRSVGDF 253
 
Name Accession Description Interval E-value
ComEA COG1555
DNA uptake protein ComE or related DNA-binding protein [Replication, recombination and repair]; ...
 127-195 2.07e-23

DNA uptake protein ComE or related DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 441164 [Multi-domain]  Cd Length: 72  Bit Score: 91.08  E-value: 2.07e-23
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568959964 127 LTTTVPLTPRVNINTATLAQLMSVRGLSEKMALSIVDYRREHGPFRSVEDLVRMDGINAAFLDRIRHQV 195
Cdd:COG1555    3 ASASAAAGGKVDINTATAEELQTLPGIGPKLAQRIVEYREKNGPFKSVEDLLEVKGIGPKTLEKLKPYL 71
ComEA COG1555
DNA uptake protein ComE or related DNA-binding protein [Replication, recombination and repair]; ...
 38-95 3.55e-22

DNA uptake protein ComE or related DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 441164 [Multi-domain]  Cd Length: 72  Bit Score: 88.00  E-value: 3.55e-22
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 568959964  38 ERLNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVK 95
Cdd:COG1555   11 GKVDINTATAEELQTLPGIGPKLAQRIVEYREKNGPFKSVEDLLEVKGIGPKTLEKLK 68
HHH_3 pfam12836
Helix-hairpin-helix motif; The HhH domain is a short DNA-binding domain.
 37-95 1.31e-19

Helix-hairpin-helix motif; The HhH domain is a short DNA-binding domain.


Pssm-ID: 463723 [Multi-domain]  Cd Length: 62  Bit Score: 80.60  E-value: 1.31e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568959964   37 QERLNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVK 95
Cdd:pfam12836   1 AVGVDINTASAELLSRVPGLGPKLAKNIVEYREENGPFRSREDLLKVKGLGPKTFEQLA 59
HHH_3 pfam12836
Helix-hairpin-helix motif; The HhH domain is a short DNA-binding domain.
 136-195 7.96e-19

Helix-hairpin-helix motif; The HhH domain is a short DNA-binding domain.


Pssm-ID: 463723 [Multi-domain]  Cd Length: 62  Bit Score: 78.68  E-value: 7.96e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959964  136 RVNINTATLAQLMSVRGLSEKMALSIVDYRREHGPFRSVEDLVRMDGINAAFLDRIRHQV 195
Cdd:pfam12836   3 GVDINTASAELLSRVPGLGPKLAKNIVEYREENGPFRSREDLLKVKGLGPKTFEQLAGFL 62
comE TIGR01259
comEA protein; This model describes the ComEA protein in bacteria. The com E locus is ...
 40-100 7.35e-14

comEA protein; This model describes the ComEA protein in bacteria. The com E locus is obligatory for bacterial cell competence - the process of internalizing the exogenous added DNA. Lesions in the loci has been variously described for the appearance of competence-related pheonotypes and impairment of competence, suggesting their intimate functional role in bacterial transformation. [Cellular processes, DNA transformation]


Pssm-ID: 213597 [Multi-domain]  Cd Length: 120  Bit Score: 66.85  E-value: 7.35e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568959964   40 LNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICV 100
Cdd:TIGR01259  60 VNINAASLEELQALPGIGPAKAKAIIEYREENGAFKSVDDLTKVSGIGEKSLEKLKDYATV 120
comE TIGR01259
comEA protein; This model describes the ComEA protein in bacteria. The com E locus is ...
 137-195 2.69e-12

comEA protein; This model describes the ComEA protein in bacteria. The com E locus is obligatory for bacterial cell competence - the process of internalizing the exogenous added DNA. Lesions in the loci has been variously described for the appearance of competence-related pheonotypes and impairment of competence, suggesting their intimate functional role in bacterial transformation. [Cellular processes, DNA transformation]


Pssm-ID: 213597 [Multi-domain]  Cd Length: 120  Bit Score: 62.61  E-value: 2.69e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568959964  137 VNINTATLAQLMSVRGLSEKMALSIVDYRREHGPFRSVEDLVRMDGINAAFLDRIRHQV 195
Cdd:TIGR01259  60 VNINAASLEELQALPGIGPAKAKAIIEYREENGAFKSVDDLTKVSGIGEKSLEKLKDYA 118
TIGR00426 TIGR00426
competence protein ComEA helix-hairpin-helix repeat region; Members of the subfamily ...
 136-192 7.56e-12

competence protein ComEA helix-hairpin-helix repeat region; Members of the subfamily recognized by this model include competence protein ComEA and closely related proteins from a number of species that exhibit competence for transformation by exongenous DNA, including Streptococcus pneumoniae, Bacillus subtilis, Neisseria meningitidis, and Haemophilus influenzae. This model represents a region of two tandem copies of a helix-hairpin-helix domain (pfam00633), each about 30 residues in length. Limited sequence similarity can be found among some members of this family N-terminal to the region covered by this model. [Cellular processes, DNA transformation]


Pssm-ID: 129520 [Multi-domain]  Cd Length: 69  Bit Score: 59.94  E-value: 7.56e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 568959964  136 RVNINTATLAQLM-SVRGLSEKMALSIVDYRREHGPFRSVEDLVRMDGINAAFLDRIR 192
Cdd:TIGR00426   7 RVNINTATAEELQrAMNGVGLKKAEAIVSYREEYGPFKTVEDLKQVPGIGNSLVEKNL 64
TIGR00426 TIGR00426
competence protein ComEA helix-hairpin-helix repeat region; Members of the subfamily ...
 39-100 9.13e-11

competence protein ComEA helix-hairpin-helix repeat region; Members of the subfamily recognized by this model include competence protein ComEA and closely related proteins from a number of species that exhibit competence for transformation by exongenous DNA, including Streptococcus pneumoniae, Bacillus subtilis, Neisseria meningitidis, and Haemophilus influenzae. This model represents a region of two tandem copies of a helix-hairpin-helix domain (pfam00633), each about 30 residues in length. Limited sequence similarity can be found among some members of this family N-terminal to the region covered by this model. [Cellular processes, DNA transformation]


Pssm-ID: 129520 [Multi-domain]  Cd Length: 69  Bit Score: 56.86  E-value: 9.13e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568959964   39 RLNINTATEEELM-TLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICV 100
Cdd:TIGR00426   7 RVNINTATAEELQrAMNGVGLKKAEAIVSYREEYGPFKTVEDLKQVPGIGNSLVEKNLAVITL 69
Tex COG2183
Transcriptional accessory protein Tex/SPT6 [Transcription];
137-177 7.96e-08

Transcriptional accessory protein Tex/SPT6 [Transcription];


Pssm-ID: 441786 [Multi-domain]  Cd Length: 719  Bit Score: 53.49  E-value: 7.96e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 568959964 137 VNINTATlAQLMS-VRGLSEKMALSIVDYRREHGPFRSVEDL 177
Cdd:COG2183  487 VDLNTAS-APLLSyVSGLNPTLAKNIVAYRDENGAFKSRKEL 527
HHH pfam00633
Helix-hairpin-helix motif; The helix-hairpin-helix DNA-binding motif is found to be duplicated ...
 41-67 2.27e-06

Helix-hairpin-helix motif; The helix-hairpin-helix DNA-binding motif is found to be duplicated in the central domain of RuvA. The HhH domain of DisA, a bacterial checkpoint control protein, is a DNA-binding domain.


Pssm-ID: 425789 [Multi-domain]  Cd Length: 30  Bit Score: 43.56  E-value: 2.27e-06
                          10        20
                  ....*....|....*....|....*..
gi 568959964   41 NINTATEEELMTLPGVTRAVARSIVEY 67
Cdd:pfam00633   4 GLIPASVEELLALPGVGPKTAEAILSY 30
DnaE COG0587
DNA polymerase III, alpha subunit [Replication, recombination and repair];
147-179 3.07e-05

DNA polymerase III, alpha subunit [Replication, recombination and repair];


Pssm-ID: 440352 [Multi-domain]  Cd Length: 1050  Bit Score: 45.45  E-value: 3.07e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 568959964  147 LMSVRGLSEKMALSIVDYRREHGPFRSVEDLVR 179
Cdd:COG0587   817 LGAIKGVGEAAAEAIVAAREENGPFTSLFDFCR 849
PulK COG3156
Type II secretory pathway, component PulK [Intracellular trafficking, secretion, and vesicular ...
 39-93 3.35e-05

Type II secretory pathway, component PulK [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442390 [Multi-domain]  Cd Length: 307  Bit Score: 44.60  E-value: 3.35e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 568959964  39 RLNINTATEEELMTL-PGVTRAVARSIVEYREyIGGFKKVEDLALVSGVGATKLEQ 93
Cdd:COG3156  212 KINVNTAPPEVLAALlGGLSLDDAQALLAARP-EKGFADVADFLALLGLAGLDLLK 266
Tex COG2183
Transcriptional accessory protein Tex/SPT6 [Transcription];
35-93 1.05e-04

Transcriptional accessory protein Tex/SPT6 [Transcription];


Pssm-ID: 441786 [Multi-domain]  Cd Length: 719  Bit Score: 43.86  E-value: 1.05e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 568959964  35 VNQERLNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQ 93
Cdd:COG2183  482 VNAVGVDLNTASAPLLSYVSGLNPTLAKNIVAYRDENGAFKSRKELLKVPRLGPKAFEQ 540
dnaE2 PRK05672
error-prone DNA polymerase; Validated
 110-189 1.48e-04

error-prone DNA polymerase; Validated


Pssm-ID: 235553 [Multi-domain]  Cd Length: 1046  Bit Score: 43.31  E-value: 1.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959964  110 SPSSLrrdlLAEQQPHHLTTTVP----------LTPRVNINTATLAQLMSVRGLSEKMALSIVDyRREHGPFRSVEDLVR 179
Cdd:PRK05672  775 SPQQL----VQDARRHGVEVLPVdvnasgwdatLEPLPDGGPAVRLGLRLVRGLGEEAAERIVA-ARARGPFTSVEDLAR 849

                          90
                  ....*....|
gi 568959964  180 MDGINAAFLD 189
Cdd:PRK05672  850 RAGLDRRQLE 859
T2SS_GspK NF037980
type II secretion system minor pseudopilin GspK;
33-95 1.76e-04

type II secretion system minor pseudopilin GspK;


Pssm-ID: 468299 [Multi-domain]  Cd Length: 311  Bit Score: 42.66  E-value: 1.76e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568959964  33 ILVNQERLNINTATEEELMTL-PGVTRAVARSIVEYREYiGGFKKVEDLALVSGVGATKLEQVK 95
Cdd:NF037980 206 LPTTTLAINVNTAPAEVLAALaALLSLSQARALLAARPA-AGFRSVGDFLAQLALAGLALDASD 268
PulK COG3156
Type II secretory pathway, component PulK [Intracellular trafficking, secretion, and vesicular ...
 110-190 3.02e-04

Type II secretory pathway, component PulK [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442390 [Multi-domain]  Cd Length: 307  Bit Score: 41.91  E-value: 3.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959964 110 SPSSLR------RDLLAEQQPHhlTTTVPLTPRVNINTATLAQLMSV-RGLSEKMALSIVDYRREhGPFRSVEDLVRMDG 182
Cdd:COG3156  182 SVSELRlvkgmtPELYARLAPY--VTALPGDTKINVNTAPPEVLAALlGGLSLDDAQALLAARPE-KGFADVADFLALLG 258


                 ....*...
gi 568959964 183 INAAFLDR 190
Cdd:COG3156  259 LAGLDLLK 266
T2SS_GspK NF037980
type II secretion system minor pseudopilin GspK;
109-177 3.25e-04

type II secretion system minor pseudopilin GspK;


Pssm-ID: 468299 [Multi-domain]  Cd Length: 311  Bit Score: 41.89  E-value: 3.25e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568959964 109 HSPSSLRR------DLLAEQQPHhLTTTVPLTPRVNINTATLAQLMSVR-GLSEKMALSIVDyRREHGPFRSVEDL 177
Cdd:NF037980 180 ADVSELRLvpgvtpALYARLRPY-VCALPTTTLAINVNTAPAEVLAALAaLLSLSQARALLA-ARPAAGFRSVGDF 253
T2SSK pfam03934
Type II secretion system (T2SS), protein K; Members of this family are involved in the Type II ...
 39-102 4.98e-04

Type II secretion system (T2SS), protein K; Members of this family are involved in the Type II protein secretion system. The T2SK family includes proteins such as ExeK, PulK, OutX and XcpX.


Pssm-ID: 427597 [Multi-domain]  Cd Length: 283  Bit Score: 41.16  E-value: 4.98e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568959964   39 RLNINTATEEELMTL-PGVTRAVARSIVEYREyIGGFKKVED---LALVSGVGATKLEQVKFEICVSS 102
Cdd:pfam03934 185 PINVNTAPAEVLAALfDGLSLDQAQALLAQRP-ADGFESVDDflaQPALGGGIAPSTAQLKTLLTVKS 251
HHH_6 pfam14579
Helix-hairpin-helix motif; The HHH domain is a short DNA-binding domain.
 147-179 1.24e-03

Helix-hairpin-helix motif; The HHH domain is a short DNA-binding domain.


Pssm-ID: 434050 [Multi-domain]  Cd Length: 88  Bit Score: 37.45  E-value: 1.24e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 568959964  147 LMSVRGLSEKMALSIVDyRREHGPFRSVEDLVR 179
Cdd:pfam14579  27 LGAIKGLGEAAAERIVE-ERENGPFKSLEDFAR 58
HHH_5 pfam14520
Helix-hairpin-helix domain;
47-98 1.60e-03

Helix-hairpin-helix domain;


Pssm-ID: 434010 [Multi-domain]  Cd Length: 57  Bit Score: 35.93  E-value: 1.60e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959964   47 EEELMTLPGVTRAVARSIVEyreyiGGFKKVEDLA--------LVSGVGATKLEQVKFEI 98
Cdd:pfam14520   1 FEELLSISGIGPKTALALLS-----AGIGTVEDLAeadvdelaEIPGIGEKTAQRIILEL 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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