NCBI Conserved Domain Search

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

1067-1423

4.00e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 101.17 E-value: 4.00e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1067 IRTEQQAALQRLREEAETLQKAERASLEQKSRRA------LEQLREQLEAEERSAqaalraekeaekeaallqlrEQLEG 1140
Cdd:COG1196   194 ILGELERQLEPLERQAEKAERYRELKEELKELEAellllkLRELEAELEELEAEL--------------------EELEA 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1141 ERKEAVAGLEKKHsAELEQlcssLEAKHQEvissLQKKIEGAQQKEEAQLQESLGWAEQRAHqkvhqvteyEQELSSLLR 1220
Cdd:COG1196   254 ELEELEAELAELE-AELEE----LRLELEE----LELELEEAQAEEYELLAELARLEQDIAR---------LEERRRELE 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1221 DKRQEVEREHERKMDKMKEEHwQEMADARERYEAEERKQRadllghltgELERLRRAHERELESMRQEQDQQLEDLRRRH 1300
Cdd:COG1196   316 ERLEELEEELAELEEELEELE-EELEELEEELEEAEEELE---------EAEAELAEAEEALLEAEAELAEAEEELEELA 385

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1301 RDHERKLQDLEvELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEAtatHQHLEEAKKEHTHLLETKQQL 1380
Cdd:COG1196   386 EELLEALRAAA-ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE---EEALEEAAEEEAELEEEEEAL 461

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 568959107 1381 RRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQ 1423
Cdd:COG1196   462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

1054-1387

3.88e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 91.66 E-value: 3.88e-18

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1054 AQVQSRTEAFENQIRtEQQAALQRLREEAETLQKAERA--SLEQKSRRALEQLREQLEAEERSAQAalraekeaekeaaL 1131
Cdd:TIGR02168  680 EELEEKIEELEEKIA-ELEKALAELRKELEELEEELEQlrKELEELSRQISALRKDLARLEAEVEQ-------------L 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1132 LQLREQLEGERKEAVAGLEKKHsAELEQLCSSLEAkHQEVISSLQKKIEgaQQKEEAQLQESLGWAEQRAHQ----KVHQ 1207
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELE-ERLEEAEEELAE-AEAEIEELEAQIE--QLKEELKALREALDELRAELTllneEAAN 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1208 VTEYEQELSSLLRDKRQEVEREHERKmdKMKEEHWQEMADARERYEAEERKQRADLLGHLtgeleRLRRAHERELESMRQ 1287
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQI--EELSEDIESLAAEIEELEELIEELESELEALL-----NERASLEEALALLRS 894

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1288 EqdqqLEDLRRRHRDHERKLQDLEVELSSRTK---DVKARLAQLNVQEENIR--------------KEKQLLLDAQRQAA 1350
Cdd:TIGR02168  895 E----LEELSEELRELESKRSELRRELEELREklaQLELRLEGLEVRIDNLQerlseeysltleeaEALENKIEDDEEEA 970

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 568959107  1351 LER-------------------EEATATHQHLEEAKKEHTHLLETKQQLRRTIDDL 1387
Cdd:TIGR02168  971 RRRlkrlenkikelgpvnlaaiEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEI 1026

PTZ00121

MAEBL; Provisional

922-1582

6.94e-16

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 84.42 E-value: 6.94e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  922 KEASALENTSDVSEESEIHGHLKDARHSGSEASgpKSFLGLDLGFRSRISEHLLDGDTLSpVLGGGHWEAQGLDQEEQDD 1001
Cdd:PTZ00121 1030 EELTEYGNNDDVLKEKDIIDEDIDGNHEGKAEA--KAHVGQDEGLKPSYKDFDFDAKEDN-RADEATEEAFGKAEEAKKT 1106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1002 SKSSIAEPQSKhtqgSESLLKAQlqkataeeKEKEEETKIREEESRRLVCLRAQVQSRTEAFENQIRTEQQAALQRLREE 1081
Cdd:PTZ00121 1107 ETGKAEEARKA----EEAKKKAE--------DARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAED 1174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1082 AETLQKAERAsleQKSRRAlEQLREQLEAeeRSAQAALRAEKEAEKEaallQLREQLEGERKEAVAGLEKKHSAELEQLC 1161
Cdd:PTZ00121 1175 AKKAEAARKA---EEVRKA-EELRKAEDA--RKAEAARKAEEERKAE----EARKAEDAKKAEAVKKAEEAKKDAEEAKK 1244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1162 SSLEAKHQEVisslqKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLLRDKRQEVER-----EHERKMD- 1235
Cdd:PTZ00121 1245 AEEERNNEEI-----RKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEakkkaEEAKKADe 1319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1236 -KMKEEHWQEMADARERyEAEERKQRADLL-GHLTGELERLRRAHER-ELESMRQEQDQQLEDLRRRHRDHERKLQDLEV 1312
Cdd:PTZ00121 1320 aKKKAEEAKKKADAAKK-KAEEAKKAAEAAkAEAEAAADEAEAAEEKaEAAEKKKEEAKKKADAAKKKAEEKKKADEAKK 1398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1313 ---ELSSRTKDVKARLA------QLNVQEENIRKEKQLLLDAQ--------RQAALEREEATATHQHLEEAKKEHThlLE 1375
Cdd:PTZ00121 1399 kaeEDKKKADELKKAAAakkkadEAKKKAEEKKKADEAKKKAEeakkadeaKKKAEEAKKAEEAKKKAEEAKKADE--AK 1476

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1376 TKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLK--EMAAEMNASPHPEPGLHIEDLRKSLD 1453
Cdd:PTZ00121 1477 KKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKkaEEAKKADEAKKAEEKKKADELKKAEE 1556

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1454 TNKNQEVSSSLSLSKEEIDLSMESVRqflsAEgvAVRNAKEFLVRQTRSMRRRQTALKAAQ-QHWRHELASAQEVDEDLP 1532
Cdd:PTZ00121 1557 LKKAEEKKKAEEAKKAEEDKNMALRK----AE--EAKKAEEARIEEVMKLYEEEKKMKAEEaKKAEEAKIKAEELKKAEE 1630

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....
gi 568959107 1533 GTEVLGNMRKNLNEETRHLDEMKSAMR----KGHDLLKKKEEKLIQLESSLQEE 1582
Cdd:PTZ00121 1631 EKKKVEQLKKKEAEEKKKAEELKKAEEenkiKAAEEAKKAEEDKKKAEEAKKAE 1684

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

1066-1582

1.47e-14

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 79.63 E-value: 1.47e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1066 QIRTEQQAALQRLREEAEtLQKAERASLEQKSRRALEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQLEGERKEA 1145
Cdd:pfam02463  177 KLIEETENLAELIIDLEE-LKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1146 VAGLEKKHSAELEQlcSSLEAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAH----QKVHQVTEYEQELSSLLRD 1221
Cdd:pfam02463  256 SKQEIEKEEEKLAQ--VLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVddeeKLKESEKEKKKAEKELKKE 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1222 KRQEVEREHERK-MDKMKEEHWQEMADARERYEAEERKQRADLLGHLTGELERLRRAHERELESMRQEQDQQ----LEDL 1296
Cdd:pfam02463  334 KEEIEELEKELKeLEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKeaqlLLEL 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1297 RRRHRDHERKLQD------LEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEEA---- 1366
Cdd:pfam02463  414 ARQLEDLLKEEKKeeleilEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLlsrq 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1367 KKEHTHLLETKQQ-----LRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNASPHPEP 1441
Cdd:pfam02463  494 KLEERSQKESKARsglkvLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTEL 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1442 GLHIEDLRKSLDTNKNQEVSSSLSLSKEEIDLSMESVRQFLSAEGVAVRNAKEFLVRQTRSMRRRQTALKAAQ--QHWRH 1519
Cdd:pfam02463  574 PLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESglRKGVS 653

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568959107  1520 ELASAQEVDEDLPGTEVLGNMRKN--LNEETRHLDEMKSAMRKGHDLLKKKEEKLIQLESSLQEE 1582
Cdd:pfam02463  654 LEEGLAEKSEVKASLSELTKELLEiqELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLE 718

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

1345-1593

1.00e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 56.31 E-value: 1.00e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1345 AQRQAALE--REEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRK 1422
Cdd:COG4942    23 AEAEAELEqlQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1423 QDVLKEMAAE---MNASPHPEPGLHIEDlrkSLDTNKNQEVssslslskeeidlsMESVRQFLSAEGVAVRNAKEFLVRQ 1499
Cdd:COG4942   103 KEELAELLRAlyrLGRQPPLALLLSPED---FLDAVRRLQY--------------LKYLAPARREQAEELRADLAELAAL 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1500 TRS---MRRRQTALKAAQQHWRHELASAQEVDEDLpgtevLGNMRKNLNEETRHLDEmksamrkghdlLKKKEEKLIQLE 1576
Cdd:COG4942   166 RAEleaERAELEALLAELEEERAALEALKAERQKL-----LARLEKELAELAAELAE-----------LQQEAEELEALI 229

                         250
                  ....*....|....*..
gi 568959107 1577 SSLQEEVSDEDTLKGSS 1593
Cdd:COG4942   230 ARLEAEAAAAAERTPAA 246

pfam00397

WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds ...

58-87

1.37e-05

WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds proline-rich peptide motifs in vitro.

Pssm-ID: 459800 [Multi-domain] Cd Length: 30 Bit Score: 43.26 E-value: 1.37e-05

                           10        20        30
                   ....*....|....*....|....*....|
gi 568959107    58 LPKGWKPCQNITGDLYYFNFDTGQSIWDHP 87
Cdd:pfam00397    1 LPPGWEERWDPDGRVYYYNHETGETQWEKP 30

Spc7

smart00787

Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...

1271-1423

2.04e-05

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.

Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 48.48 E-value: 2.04e-05

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107   1271 LERLRRAHERELESMRQEqDQQLedlrrrhRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRqaa 1350
Cdd:smart00787  142 LEGLKEGLDENLEGLKED-YKLL-------MKELELLNSIKPKLRDRKDALEEELRQLKQLEDELEDCDPTELDRAK--- 210

                            90       100       110       120       130       140       150
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568959107   1351 lerEEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDllQAQSQRLQ------KHLSSLEAEVQRKQ 1423
Cdd:smart00787  211 ---EKLKKLLQEIMIKVKKLEELEEELQELESKIEDLTNKKSELNTEIA--EAEKKLEQcrgftfKEIEKLKEQLKLLQ 284

growth_prot_Scy

polarized growth protein Scy;

1053-1409

2.49e-05

polarized growth protein Scy;

Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 49.44 E-value: 2.49e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1053 RAQVQSRTEAFENQIRTEQQAALQRLREEA---ETLQKAE--RASLEQKSRRALEQLReqleAEERSAQAALRAEKEAEK 1127
Cdd:NF041483  116 RLQAELHTEAVQRRQQLDQELAERRQTVEShvnENVAWAEqlRARTESQARRLLDESR----AEAEQALAAARAEAERLA 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1128 EAALLQLREQLEGERKEAVAGLeKKHSAELEQLCSSLEAKHQEVIS-SLQKKIEGAQQKEEA--QLQESLGWAEQRAhqk 1204
Cdd:NF041483  192 EEARQRLGSEAESARAEAEAIL-RRARKDAERLLNAASTQAQEATDhAEQLRSSTAAESDQArrQAAELSRAAEQRM--- 267

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1205 vhqvteyeQELSSLLRDKRQEVerehERKMDKMKEEHWQEMADARERYEAEER---KQRADLLGHLTGELERLRRAHERE 1281
Cdd:NF041483  268 --------QEAEEALREARAEA----EKVVAEAKEAAAKQLASAESANEQRTRtakEEIARLVGEATKEAEALKAEAEQA 335

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1282 LESMRQEQDQQLEDLRRRHR-----DHERKL----QDLEVELSSRTKDVKARLAQLNVQEENIRKEkqllldAQRQAALE 1352
Cdd:NF041483  336 LADARAEAEKLVAEAAEKARtvaaeDTAAQLakaaRTAEEVLTKASEDAKATTRAAAEEAERIRRE------AEAEADRL 409

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 568959107 1353 REEATATHQHLEEAKKEHThlletkqqlrrtiDDLRVRRVELESQVDLLQAQSQRLQ 1409
Cdd:NF041483  410 RGEAADQAEQLKGAAKDDT-------------KEYRAKTVELQEEARRLRGEAEQLR 453

growth_prot_Scy

polarized growth protein Scy;

1059-1365

3.49e-05

polarized growth protein Scy;

Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 49.05 E-value: 3.49e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1059 RTEAFE--NQIRTEQQAALQRLREEaetlqkAERASLEQKSRRALEQLREQLEAEERSAQAalraekeaekEAALLQLRE 1136
Cdd:NF041483  537 RAEAEEqaEEVRAAAERAARELREE------TERAIAARQAEAAEELTRLHTEAEERLTAA----------EEALADARA 600

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1137 QLEGERKEAVAGLEKkhsaeleqlcssLEAKHQEVISSLQkkiegAQQKEEAQLQESLGWAEQRAHQkvhqvTEYEQELS 1216
Cdd:NF041483  601 EAERIRREAAEETER------------LRTEAAERIRTLQ-----AQAEQEAERLRTEAAADASAAR-----AEGENVAV 658

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1217 SLLRDKRQEVER---EHERKMDKMKeehwQEMADARERYEAEErkqrADLLGHLTGELERLRRAHERELESMRQEQDQQl 1293
Cdd:NF041483  659 RLRSEAAAEAERlksEAQESADRVR----AEAAAAAERVGTEA----AEALAAAQEEAARRRREAEETLGSARAEADQE- 729

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568959107 1294 edlRRRHRDherklQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEE 1365
Cdd:NF041483  730 ---RERARE-----QSEELLASARKRVEEAQAEAQRLVEEADRRATELVSAAEQTAQQVRDSVAGLQEQAEE 793

cd00201

Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ...

59-89

5.04e-05

Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other peptide recognition proteins such as antibodies and receptors; WW domains have a single groove formed by a conserved Trp and Tyr which recognizes a pair of residues of the sequence X-Pro; variable loops and neighboring domains confer specificity in this domain; there are five distinct groups based on binding: 1) PPXY motifs 2) the PPLP motif; 3) PGM motifs; 4) PSP or PTP motifs; 5) PR motifs.

Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 41.74 E-value: 5.04e-05

                          10        20        30
                  ....*....|....*....|....*....|.
gi 568959107   59 PKGWKPCQNITGDLYYFNFDTGQSIWDHPCD 89
Cdd:cd00201     1 PPGWEERWDPDGRVYYYNHNTKETQWEDPRE 31

growth_prot_Scy

polarized growth protein Scy;

1060-1588

7.57e-05

polarized growth protein Scy;

Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 47.90 E-value: 7.57e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1060 TEAFENQIRTEQQAAlqRLREEAETLQKAERASLEQKSRRALEQLREQLEA-----EERSAQAALRAEKEAEKEAALLQL 1134
Cdd:NF041483  695 TEAAEALAAAQEEAA--RRRREAEETLGSARAEADQERERAREQSEELLASarkrvEEAQAEAQRLVEEADRRATELVSA 772

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1135 REQLEGERKEAVAGLEKKHSAELEQLCSSLEAKHQEVISSLQK-----KIEGAQQKEEA---------QLQESLGWAEQR 1200
Cdd:NF041483  773 AEQTAQQVRDSVAGLQEQAEEEIAGLRSAAEHAAERTRTEAQEeadrvRSDAYAERERAsedanrlrrEAQEETEAAKAL 852

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1201 AHQKVHQVTEYEQELSSLLRDKRQEVEREHERKMDKMKEEHWQEMADARE---RYEAEERKQRADLLGHLTGELERLRRA 1277
Cdd:NF041483  853 AERTVSEAIAEAERLRSDASEYAQRVRTEASDTLASAEQDAARTRADAREdanRIRSDAAAQADRLIGEATSEAERLTAE 932

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1278 HERELESMRQEQDQQLEdlrRRHRDHERKLQDLEVELSSRTKDVKARLAQLnvqeenirkekqlLLDAQRQAALEREEAt 1357
Cdd:NF041483  933 ARAEAERLRDEARAEAE---RVRADAAAQAEQLIAEATGEAERLRAEAAET-------------VGSAQQHAERIRTEA- 995

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1358 atHQHLEEAKKEHTHLL-ETKQQLRRTIDDLRV----RRVELESQVDLLQAQSQRLQKHLssleaeVQRKQDVLKEMAAE 1432
Cdd:NF041483  996 --ERVKAEAAAEAERLRtEAREEADRTLDEARKdankRRSEAAEQADTLITEAAAEADQL------TAKAQEEALRTTTE 1067

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1433 MNAsphpepglhiedlrksldtnknQEVSSSLSLSKEEIDLSMESVRQFLSAEGVAVRNAKEFLVrqtrSMRRRQTALKA 1512
Cdd:NF041483 1068 AEA----------------------QADTMVGAARKEAERIVAEATVEGNSLVEKARTDADELLV----GARRDATAIRE 1121

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568959107 1513 AQQHWRHELASaqEVDEdlpgtevlgnmrknLNEETRH--LDEMKSAMRKGHDLLKKKEEKLIQLESSLQEEVSDEDT 1588
Cdd:NF041483 1122 RAEELRDRITG--EIEE--------------LHERARResAEQMKSAGERCDALVKAAEEQLAEAEAKAKELVSDANS 1183

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

1061-1180

1.88e-04

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 45.65 E-value: 1.88e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1061 EAFENQIRTEQQAALQRLREEAETLQKAERASLEQKSRRA-LEQLREQLEAEERSAQAALRaekeaekeaallQLREQLE 1139
Cdd:cd16269   180 EAEAEAILQADQALTEKEKEIEAERAKAEAAEQERKLLEEqQRELEQKLEDQERSYEEHLR------------QLKEKME 247

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 568959107 1140 GERKEAVAGLEKKHSAELEQLCSSLEAKHQEVISSLQKKIE 1180
Cdd:cd16269   248 EERENLLKEQERALESKLKEQEALLEEGFKEQAELLQEEIR 288

smart00456

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ...

57-87

2.83e-04

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides.

Pssm-ID: 197736 [Multi-domain] Cd Length: 33 Bit Score: 39.89 E-value: 2.83e-04

                            10        20        30
                    ....*....|....*....|....*....|.
gi 568959107     57 PLPKGWKPCQNITGDLYYFNFDTGQSIWDHP 87
Cdd:smart00456    1 PLPPGWEERKDPDGRPYYYNHETKETQWEKP 31

PLN02939

transferase, transferring glycosyl groups

1275-1581

3.97e-04

transferase, transferring glycosyl groups

Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 45.28 E-value: 3.97e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1275 RRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENI-------RKEKQLLLDAQR 1347
Cdd:PLN02939   36 RARRRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDhnrasmqRDEAIAAIDNEQ 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1348 QAALEREEATATHQhLEEakkehthLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLK 1427
Cdd:PLN02939  116 QTNSKDGEQLSDFQ-LED-------LVGMIQNAEKNILLLNQARLQALEDLEKILTEKEALQGKINILEMRLSETDARIK 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1428 eMAAEMNAspHPE-PGLHIEDLRKSLDTNKNQEVSSSLSLSKEEIDLSMESVR-----QFLSAEGVAVRNAKEFLVRqtr 1501
Cdd:PLN02939  188 -LAAQEKI--HVEiLEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLlkddiQFLKAELIEVAETEERVFK--- 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1502 sMRRRQTALKAAQQHWRHELASAQE---------VDEDLPGTEVLGNMrknLNEETRHLDEMKSAMRKGHDLLKKKEEkl 1572
Cdd:PLN02939  262 -LEKERSLLDASLRELESKFIVAQEdvsklsplqYDCWWEKVENLQDL---LDRATNQVEKAALVLDQNQDLRDKVDK-- 335


                  ....*....
gi 568959107 1573 iqLESSLQE 1581
Cdd:PLN02939  336 --LEASLKE 342

PHA03247

large tegument protein UL36; Provisional

325-740

6.14e-04

large tegument protein UL36; Provisional

Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 44.93 E-value: 6.14e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  325 PGGDKGQNTAPLPPSEEEPSLSlgSSDHALPARRNKLFLLESGPAEDLSWQGVPGEGGDVGRERWRRESPGLwmgqvSKL 404
Cdd:PHA03247 2601 PVDDRGDPRGPAPPSPLPPDTH--APDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRL-----GRA 2673

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  405 INKDTPERcKETEPAAPK---DAEASAEDSPQGPSPMPPETLASEPVPKPPLGDPANEDRQHPPGSLEPLNEDGKPSTPG 481
Cdd:PHA03247 2674 AQASSPPQ-RPRRRAARPtvgSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPG 2752

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  482 TDS------------------DNSSGGGSSLASPLGSQVLGEINNFPWDLQNPQGSVPVMGPLGPGPRDVRFCPFLVPQL 543
Cdd:PHA03247 2753 GPArparppttagppapappaAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPT 2832

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  544 SHISSVEEQSesedySEDQRFYQHILQMVKISRQLEGLGLPENMQEMPCKDVAGMVCSMANEPSRMSNKGDHKATRAPER 623
Cdd:PHA03247 2833 SAQPTAPPPP-----PGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPER 2907

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  624 DSgllawGPELLEHPLgaVSAPAGQEATQQAQCQPSGLRQGPVQPSPDTGLGAEPSKMQLLSQVLGSPLALVQAPLWGL- 702
Cdd:PHA03247 2908 PP-----QPQAPPPPQ--PQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVp 2980

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 568959107  703 --APLRGLGDAPPSALRGSQSVSLGSSADSGHLGEPTLPP 740
Cdd:PHA03247 2981 qpAPSREAPASSTPPLTGHSLSRVSSWASSLALHEETDPP 3020

Filament

pfam00038

Intermediate filament protein;

1304-1568

9.50e-03

Intermediate filament protein;

Pssm-ID: 459643 [Multi-domain] Cd Length: 313 Bit Score: 40.29 E-value: 9.50e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1304 ERKLQDLEVELSSRTKDVKARLAQL-NVQEENIRKEKQLLLDAQRQAA---LEREEATATHQHL----EEAKKEHTHLLE 1375
Cdd:pfam00038   24 EQQNKLLETKISELRQKKGAEPSRLySLYEKEIEDLRRQLDTLTVERArlqLELDNLRLAAEDFrqkyEDELNLRTSAEN 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1376 TKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHlssLEAEVQ--RKQDVLKEMAAEMNASPHPEPGLHIEDLRKSLD 1453
Cdd:pfam00038  104 DLVGLRKDLDEATLARVDLEAKIESLKEELAFLKKN---HEEEVRelQAQVSDTQVNVEMDAARKLDLTSALAEIRAQYE 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1454 --TNKNQEVSSSLSLSKEEiDLSMESVRQflsaeGVAVRNAKEFLVRQTRSMRRRQT---ALKAAQQHWRHELASAQEVd 1528
Cdd:pfam00038  181 eiAAKNREEAEEWYQSKLE-ELQQAAARN-----GDALRSAKEEITELRRTIQSLEIelqSLKKQKASLERQLAETEER- 253

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 568959107  1529 edlpGTEVLGNMRKNLNEETRHLDEMKSAM----RKGHDLLKKK 1568
Cdd:pfam00038  254 ----YELQLADYQELISELEAELQETRQEMarqlREYQELLNVK 293

Name

Accession

Description

Interval

E-value

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

1067-1423

4.00e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 101.17 E-value: 4.00e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1067 IRTEQQAALQRLREEAETLQKAERASLEQKSRRA------LEQLREQLEAEERSAqaalraekeaekeaallqlrEQLEG 1140
Cdd:COG1196   194 ILGELERQLEPLERQAEKAERYRELKEELKELEAellllkLRELEAELEELEAEL--------------------EELEA 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1141 ERKEAVAGLEKKHsAELEQlcssLEAKHQEvissLQKKIEGAQQKEEAQLQESLGWAEQRAHqkvhqvteyEQELSSLLR 1220
Cdd:COG1196   254 ELEELEAELAELE-AELEE----LRLELEE----LELELEEAQAEEYELLAELARLEQDIAR---------LEERRRELE 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1221 DKRQEVEREHERKMDKMKEEHwQEMADARERYEAEERKQRadllghltgELERLRRAHERELESMRQEQDQQLEDLRRRH 1300
Cdd:COG1196   316 ERLEELEEELAELEEELEELE-EELEELEEELEEAEEELE---------EAEAELAEAEEALLEAEAELAEAEEELEELA 385

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1301 RDHERKLQDLEvELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEAtatHQHLEEAKKEHTHLLETKQQL 1380
Cdd:COG1196   386 EELLEALRAAA-ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE---EEALEEAAEEEAELEEEEEAL 461

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 568959107 1381 RRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQ 1423
Cdd:COG1196   462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

1053-1582

1.08e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 93.08 E-value: 1.08e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1053 RAQVQSRTEAFENQIRtEQQAALQRLREEAETLQkAERASLEQKsRRALEQLREQLEAEERSAQAALRAekeaekeaalL 1132
Cdd:COG1196   234 LRELEAELEELEAELE-ELEAELEELEAELAELE-AELEELRLE-LEELELELEEAQAEEYELLAELAR----------L 300

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1133 QLREQLEGERKEAVAglekkhsAELEQLcssleakhQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVhqvtEYE 1212
Cdd:COG1196   301 EQDIARLEERRRELE-------ERLEEL--------EEELAELEEELEELEEELEELEEELEEAEEELEEAEA----ELA 361

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1213 QELSSLLRDKRQEVEREHERkmdkmkEEHWQEMADARERyEAEERKQRADLLGHLTGELERLRRAHERELEsmRQEQDQQ 1292
Cdd:COG1196   362 EAEEALLEAEAELAEAEEEL------EELAEELLEALRA-AAELAAQLEELEEAEEALLERLERLEEELEE--LEEALAE 432

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1293 LEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALER---EEATATHQHLEEAKKE 1369
Cdd:COG1196   433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLlllLEAEADYEGFLEGVKA 512

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1370 hTHLLETKQQLRRTIDDLRVRRVELEsQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNASPHPEPGLHIEDLR 1449
Cdd:COG1196   513 -ALLLAGLRGLAGAVAVLIGVEAAYE-AALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAA 590

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1450 KSLDTNKNQEVSSSLSLSKEEIDLSMESVRQFLSAEGVAVRNAKEFLVRQTRSMRRRQTALKAAQQHWRHELASAQEVDE 1529
Cdd:COG1196   591 ALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRREL 670

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|...
gi 568959107 1530 DLPGTEVLGNMRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKLIQLESSLQEE 1582
Cdd:COG1196   671 LAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEE 723

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

1054-1387

3.88e-18

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 91.66 E-value: 3.88e-18

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1054 AQVQSRTEAFENQIRtEQQAALQRLREEAETLQKAERA--SLEQKSRRALEQLREQLEAEERSAQAalraekeaekeaaL 1131
Cdd:TIGR02168  680 EELEEKIEELEEKIA-ELEKALAELRKELEELEEELEQlrKELEELSRQISALRKDLARLEAEVEQ-------------L 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1132 LQLREQLEGERKEAVAGLEKKHsAELEQLCSSLEAkHQEVISSLQKKIEgaQQKEEAQLQESLGWAEQRAHQ----KVHQ 1207
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELE-ERLEEAEEELAE-AEAEIEELEAQIE--QLKEELKALREALDELRAELTllneEAAN 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1208 VTEYEQELSSLLRDKRQEVEREHERKmdKMKEEHWQEMADARERYEAEERKQRADLLGHLtgeleRLRRAHERELESMRQ 1287
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQI--EELSEDIESLAAEIEELEELIEELESELEALL-----NERASLEEALALLRS 894

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1288 EqdqqLEDLRRRHRDHERKLQDLEVELSSRTK---DVKARLAQLNVQEENIR--------------KEKQLLLDAQRQAA 1350
Cdd:TIGR02168  895 E----LEELSEELRELESKRSELRRELEELREklaQLELRLEGLEVRIDNLQerlseeysltleeaEALENKIEDDEEEA 970

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 568959107  1351 LER-------------------EEATATHQHLEEAKKEHTHLLETKQQLRRTIDDL 1387
Cdd:TIGR02168  971 RRRlkrlenkikelgpvnlaaiEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEI 1026

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

1059-1435

4.71e-18

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 91.27 E-value: 4.71e-18

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1059 RTEAfENQIRtEQQAALQRLREEAETLQKAERaSLEQKSRRAlEQLREqLEAEERSAQAALRAEKEAEKEAALLQLREQL 1138
Cdd:TIGR02168  174 RKET-ERKLE-RTRENLDRLEDILNELERQLK-SLERQAEKA-ERYKE-LKAELRELELALLVLRLEELREELEELQEEL 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1139 ---EGERKEAVAGLEKKHsAELEQlcssLEAKHQEVisslqkkiegaqQKEEAQLQESLGWAEQRAHQKVHQVTEYEQEL 1215
Cdd:TIGR02168  249 keaEEELEELTAELQELE-EKLEE----LRLEVSEL------------EEEIEELQKELYALANEISRLEQQKQILRERL 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1216 SSLLRD-KRQEVEREH-ERKMDKMKEEhwqemadareryEAEERKQRADLLGHLTGELERLRRAHE--RELESMRQEQDQ 1291
Cdd:TIGR02168  312 ANLERQlEELEAQLEElESKLDELAEE------------LAELEEKLEELKEELESLEAELEELEAelEELESRLEELEE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1292 QLEDLRRRHRDHERKLQDLEVELSSrtkdVKARLAQLNVQEENIRKEKQLLLDAQRQAALEreeatATHQHLEEAKKEHT 1371
Cdd:TIGR02168  380 QLETLRSKVAQLELQIASLNNEIER----LEARLERLEDRRERLQQEIEELLKKLEEAELK-----ELQAELEELEEELE 450

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568959107  1372 HLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNA 1435
Cdd:TIGR02168  451 ELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKN 514

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

1053-1587

3.93e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 88.07 E-value: 3.93e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1053 RAQVQSRTEAFENQIRtEQQAALQRLREEAETLQKAERASLEQKSR--RALEQLREQL-EAEERSAQAALRAEKEAEKEA 1129
Cdd:COG1196   255 LEELEAELAELEAELE-ELRLELEELELELEEAQAEEYELLAELARleQDIARLEERRrELEERLEELEEELAELEEELE 333

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1130 ALLQLREQLEGERKEAVAGLEkkhsaELEQLCSSLEAKHQEVISSLQKKIEGAQQKEEAQLQeslgwAEQRAHQKVHQVT 1209
Cdd:COG1196   334 ELEEELEELEEELEEAEEELE-----EAEAELAEAEEALLEAEAELAEAEEELEELAEELLE-----ALRAAAELAAQLE 403

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1210 EYEQELSSLLRDKRQEVEREHERkmdkmkEEHWQEMADARERYEAEERKQRADLLGHLTgELERLRRAHERELESMRQEQ 1289
Cdd:COG1196   404 ELEEAEEALLERLERLEEELEEL------EEALAELEEEEEEEEEALEEAAEEEAELEE-EEEALLELLAELLEEAALLE 476

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1290 DQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLD---AQRQAALEREEATATHQHLEEA 1366
Cdd:COG1196   477 AALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGveaAYEAALEAALAAALQNIVVEDD 556

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1367 K--KEHTHLLETKQQLRRTIDDLRVRRVElesqvDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNAsphpepglh 1444
Cdd:COG1196   557 EvaAAAIEYLKAAKAGRATFLPLDKIRAR-----AALAAALARGAIGAAVDLVASDLREADARYYVLGDTL--------- 622

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1445 IEDLRKSLDTNKNQEVSSSLSLSKEEIDLSMESVRQFLSAEGVAVRNAKEFLVRQtrsmRRRQTALKAAQQHWRHELASA 1524
Cdd:COG1196   623 LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEA----EAELEELAERLAEEELELEEA 698

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568959107 1525 QEVDEDlpgtevLGNMRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKLIQLESSLQEEVSDED 1587
Cdd:COG1196   699 LLAEEE------EERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE 755

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

1070-1585

4.69e-16

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 84.58 E-value: 4.69e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1070 EQQAALQRLREEAETLQkAERASLEQKsRRALEQLREQLEAEERSAQAALRAEKEAEKEAaLLQLREQLEGERKEAvagl 1149
Cdd:COG4913   285 FAQRRLELLEAELEELR-AELARLEAE-LERLEARLDALREELDELEAQIRGNGGDRLEQ-LEREIERLERELEER---- 357

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1150 eKKHSAELEQLCSSLEAKHQEVISSLQKKIEGAQQ------KEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLLRDK- 1222
Cdd:COG4913   358 -ERRRARLEALLAALGLPLPASAEEFAALRAEAAAllealeEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKs 436

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1223 ---------RQEVERE---HERKMD--------KMKEEHWQ---EM----------------ADARERYEAEERKQRADL 1263
Cdd:COG4913   437 niparllalRDALAEAlglDEAELPfvgelievRPEEERWRgaiERvlggfaltllvppehyAAALRWVNRLHLRGRLVY 516

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1264 LG-HLTGELERLRRAHEREL----------------ESMRQEQD-------QQLEDLRR-------------RHR----- 1301
Cdd:COG4913   517 ERvRTGLPDPERPRLDPDSLagkldfkphpfrawleAELGRRFDyvcvdspEELRRHPRaitragqvkgngtRHEkddrr 596

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1302 ----------DHERKLQDLEVE---LSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAAlEREEATATHQHLEEAKK 1368
Cdd:COG4913   597 rirsryvlgfDNRAKLAALEAElaeLEEELAEAEERLEALEAELDALQERREALQRLAEYSW-DEIDVASAEREIAELEA 675

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1369 EHTHLLETK---QQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKemAAEMNASPHPEPGLhi 1445
Cdd:COG4913   676 ELERLDASSddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE--AAEDLARLELRALL-- 751

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1446 EDLRKSLDtnknqevssslslskeeIDLSMESVRQFLSAEgvaVRNAKEFLVRQTRSMRRrqtALKAAQQHWRHELASAQ 1525
Cdd:COG4913   752 EERFAAAL-----------------GDAVERELRENLEER---IDALRARLNRAEEELER---AMRAFNREWPAETADLD 808

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568959107 1526 EVDEDLPGTEvlgNMRKNLNEE--TRHLDEMKSAmrkghdLLKKKEEKLIQLESSLQEEVSD 1585
Cdd:COG4913   809 ADLESLPEYL---ALLDRLEEDglPEYEERFKEL------LNENSIEFVADLLSKLRRAIRE 861

PTZ00121

MAEBL; Provisional

922-1582

6.94e-16

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 84.42 E-value: 6.94e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  922 KEASALENTSDVSEESEIHGHLKDARHSGSEASgpKSFLGLDLGFRSRISEHLLDGDTLSpVLGGGHWEAQGLDQEEQDD 1001
Cdd:PTZ00121 1030 EELTEYGNNDDVLKEKDIIDEDIDGNHEGKAEA--KAHVGQDEGLKPSYKDFDFDAKEDN-RADEATEEAFGKAEEAKKT 1106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1002 SKSSIAEPQSKhtqgSESLLKAQlqkataeeKEKEEETKIREEESRRLVCLRAQVQSRTEAFENQIRTEQQAALQRLREE 1081
Cdd:PTZ00121 1107 ETGKAEEARKA----EEAKKKAE--------DARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAED 1174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1082 AETLQKAERAsleQKSRRAlEQLREQLEAeeRSAQAALRAEKEAEKEaallQLREQLEGERKEAVAGLEKKHSAELEQLC 1161
Cdd:PTZ00121 1175 AKKAEAARKA---EEVRKA-EELRKAEDA--RKAEAARKAEEERKAE----EARKAEDAKKAEAVKKAEEAKKDAEEAKK 1244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1162 SSLEAKHQEVisslqKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLLRDKRQEVER-----EHERKMD- 1235
Cdd:PTZ00121 1245 AEEERNNEEI-----RKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEakkkaEEAKKADe 1319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1236 -KMKEEHWQEMADARERyEAEERKQRADLL-GHLTGELERLRRAHER-ELESMRQEQDQQLEDLRRRHRDHERKLQDLEV 1312
Cdd:PTZ00121 1320 aKKKAEEAKKKADAAKK-KAEEAKKAAEAAkAEAEAAADEAEAAEEKaEAAEKKKEEAKKKADAAKKKAEEKKKADEAKK 1398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1313 ---ELSSRTKDVKARLA------QLNVQEENIRKEKQLLLDAQ--------RQAALEREEATATHQHLEEAKKEHThlLE 1375
Cdd:PTZ00121 1399 kaeEDKKKADELKKAAAakkkadEAKKKAEEKKKADEAKKKAEeakkadeaKKKAEEAKKAEEAKKKAEEAKKADE--AK 1476

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1376 TKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLK--EMAAEMNASPHPEPGLHIEDLRKSLD 1453
Cdd:PTZ00121 1477 KKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKkaEEAKKADEAKKAEEKKKADELKKAEE 1556

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1454 TNKNQEVSSSLSLSKEEIDLSMESVRqflsAEgvAVRNAKEFLVRQTRSMRRRQTALKAAQ-QHWRHELASAQEVDEDLP 1532
Cdd:PTZ00121 1557 LKKAEEKKKAEEAKKAEEDKNMALRK----AE--EAKKAEEARIEEVMKLYEEEKKMKAEEaKKAEEAKIKAEELKKAEE 1630

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....
gi 568959107 1533 GTEVLGNMRKNLNEETRHLDEMKSAMR----KGHDLLKKKEEKLIQLESSLQEE 1582
Cdd:PTZ00121 1631 EKKKVEQLKKKEAEEKKKAEELKKAEEenkiKAAEEAKKAEEDKKKAEEAKKAE 1684

sbcc

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

993-1582

8.45e-16

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 83.86 E-value: 8.45e-16

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107   993 GLDQEEQDDSKSSIAEPQSKHTQGSESLLKAQLQKATAEEKEKEEETKIreeesrrlvclRAQVQSRTEAFENQIRTEQQ 1072
Cdd:TIGR00618  171 NLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHE-----------RKQVLEKELKHLREALQQTQ 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1073 AALQRLREEAEtlqkaeraSLEQKSRRalEQLREQLEAEERSAQAALraekeaekeAALLQLREQLEGERKEAVAGLEKK 1152
Cdd:TIGR00618  240 QSHAYLTQKRE--------AQEEQLKK--QQLLKQLRARIEELRAQE---------AVLEETQERINRARKAAPLAAHIK 300

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1153 HSAELEQ----LCSSLEAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQvtEYEQELSSLLRDKRQEVER 1228
Cdd:TIGR00618  301 AVTQIEQqaqrIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRD--AHEVATSIREISCQQHTLT 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1229 EHERKMDKMKEEHWQEMADARERYEAEERKQ---------RADLLGHL----TGELERLRRAHERELESMRQEQDQQLE- 1294
Cdd:TIGR00618  379 QHIHTLQQQKTTLTQKLQSLCKELDILQREQatidtrtsaFRDLQGQLahakKQQELQQRYAELCAAAITCTAQCEKLEk 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1295 ----DLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIR--KEKQLLLDAQRQAALEREEATATHQHLEEAKK 1368
Cdd:TIGR00618  459 ihlqESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCplCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1369 EHTHLLETkqqLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEV----QRKQDVLKEMAAEMNASPHPEPGLH 1444
Cdd:TIGR00618  539 QLETSEED---VYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIpnlqNITVRLQDLTEKLSEAEDMLACEQH 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1445 IEDLRKSLDTNkNQEVSSSLSLSKEEIDLSMESVRQFLSA-----EGVAVRNAKEFlvrQTRSMRRRQTALKAAQqhwrH 1519
Cdd:TIGR00618  616 ALLRKLQPEQD-LQDVRLHLQQCSQELALKLTALHALQLTltqerVREHALSIRVL---PKELLASRQLALQKMQ----S 687

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568959107  1520 ELASAQEVDEDLPGT-EVLGNMRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKLIQLESSLQEE 1582
Cdd:TIGR00618  688 EKEQLTYWKEMLAQCqTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQ 751

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

1012-1554

1.13e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 83.45 E-value: 1.13e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1012 KHTQGSESLLKAQLQKATAEEKEKEEETKIREEES--RRLVCLRAQVQSRTEAFE--NQIRTEQQAALQRLREEAETLQK 1087
Cdd:COG1196   223 KELEAELLLLKLRELEAELEELEAELEELEAELEEleAELAELEAELEELRLELEelELELEEAQAEEYELLAELARLEQ 302

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1088 AERASLEQKSRRALEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQLEG--ERKEAVAGLEKKHSAELEQLCSSLE 1165
Cdd:COG1196   303 DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEaeAELAEAEEALLEAEAELAEAEEELE 382

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1166 AKHQEVISSLQKKIEGAQQKEEAQLQESLgwAEQRAHQKVHQVTEYEQELSSLLRDKRQEVEREHERKMDKMKEEHWQEM 1245
Cdd:COG1196   383 ELAEELLEALRAAAELAAQLEELEEAEEA--LLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEA 460

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1246 ADARERYEAEERKQRADLLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVK--- 1322
Cdd:COG1196   461 LLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEaal 540

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1323 -----ARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLLETKQQLRRtiDDLRVRRVELESQ 1397
Cdd:COG1196   541 eaalaAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVA--SDLREADARYYVL 618

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1398 VDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNASPHPEPGLHIEDLRKSLDTNKNQEVSSSLSLSKEEIDLSMES 1477
Cdd:COG1196   619 GDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEA 698

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1478 VRQFLSAEGVAVRNAKEFLVRQTRSMRRRQTALKAAQQH----WRHELASAQEVDEDLPGTEVLGNMRKNLNEETRHLDE 1553
Cdd:COG1196   699 LLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELleelLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778


                  .
gi 568959107 1554 M 1554
Cdd:COG1196   779 L 779

PTZ00121

MAEBL; Provisional

1046-1603

4.94e-15

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 81.73 E-value: 4.94e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1046 SRRLVCLRAQVQSRTEAFEnqiRTEQQAALQRLREeAETLQKAERASLEQKSRRALEQLREQLEAEERSAQAALRAEKEA 1125
Cdd:PTZ00121 1266 ARRQAAIKAEEARKADELK---KAEEKKKADEAKK-AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEA 1341

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1126 EKEAALLQLREqlEGERKEAVAGLEKKHSAELEQlcssleakhqeviSSLQKKIEGAQQK-EEAQLQESLGWAEQRAHQK 1204
Cdd:PTZ00121 1342 KKAAEAAKAEA--EAAADEAEAAEEKAEAAEKKK-------------EEAKKKADAAKKKaEEKKKADEAKKKAEEDKKK 1406

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1205 VHQVTEYEQElssllRDKRQEVER--EHERKMDKMKEEhwqemadARERYEAEERKQRADLLGHLTGELERLRRAHEREL 1282
Cdd:PTZ00121 1407 ADELKKAAAA-----KKKADEAKKkaEEKKKADEAKKK-------AEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADE 1474

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1283 ESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQH 1362
Cdd:PTZ00121 1475 AKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKA 1554

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1363 LEEAKKEHTHLLETKqqlRRTIDDlrvRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEmaAEmnasphpEPG 1442
Cdd:PTZ00121 1555 EELKKAEEKKKAEEA---KKAEED---KNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKK--AE-------EAK 1619

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1443 LHIEDLRKSLDTNKNQEvssSLSLSKEEIDLSMESVRQflSAEGVAVRnaKEFLVRQTRSMRRRQTALKAAQQHWRHELA 1522
Cdd:PTZ00121 1620 IKAEELKKAEEEKKKVE---QLKKKEAEEKKKAEELKK--AEEENKIK--AAEEAKKAEEDKKKAEEAKKAEEDEKKAAE 1692

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1523 SAQEVDEDLPGTEvlgNMRKNLNEETRHLDEMKSA------------------MRKGHDLLKKKEEK------------- 1571
Cdd:PTZ00121 1693 ALKKEAEEAKKAE---ELKKKEAEEKKKAEELKKAeeenkikaeeakkeaeedKKKAEEAKKDEEEKkkiahlkkeeekk 1769

                         570       580       590
                  ....*....|....*....|....*....|....*.
gi 568959107 1572 ----LIQLESSLQEEVSDEDTLKGSSIKKVTFDLSD 1603
Cdd:PTZ00121 1770 aeeiRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFD 1805

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

1061-1581

7.64e-15

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 80.87 E-value: 7.64e-15

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1061 EAFENQIRTEQQAALQRLREEAETLQKAERASLEQKSRRA-LEQL---REQLEAEERSAQAALRAEKEAEKEAALLQLRE 1136
Cdd:TIGR02168  368 EELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEArLERLedrRERLQQEIEELLKKLEEAELKELQAELEELEE 447

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1137 QLEG-----ERKEAVAGLEKKHSAELEQLCSSLEAKHQEVIS------SLQKKIEGAQQ--KEEAQLQESLGWAEQRAHQ 1203
Cdd:TIGR02168  448 ELEElqeelERLEEALEELREELEEAEQALDAAERELAQLQArldsleRLQENLEGFSEgvKALLKNQSGLSGILGVLSE 527

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1204 KVHQVTEYEQELSSLLRDKRQEVE--------------REHE--------------------RKMDKMKEEHWQEMADAR 1249
Cdd:TIGR02168  528 LISVDEGYEAAIEAALGGRLQAVVvenlnaakkaiaflKQNElgrvtflpldsikgteiqgnDREILKNIEGFLGVAKDL 607

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1250 ERYEAEERKQRADLLGH------LTGELERLRRAHEREL----------------------ESMRQEQDQQLEDLRRR-- 1299
Cdd:TIGR02168  608 VKFDPKLRKALSYLLGGvlvvddLDNALELAKKLRPGYRivtldgdlvrpggvitggsaktNSSILERRREIEELEEKie 687

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1300 -----HRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLL 1374
Cdd:TIGR02168  688 eleekIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1375 ETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVL--KEMAAEMNASPHPEPGLHIEDLRKSL 1452
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAanLRERLESLERRIAATERRLEDLEEQI 847

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1453 DTNKNQEVSSSLSLSKEEIDL--------SMESVRQFLSAEGVAVRNAKEFLVRQTRSMRRRQTALKAAQQHWRHELASA 1524
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIeeleseleALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQL 927

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 568959107  1525 QevdEDLPGTEV-LGNMRKNLNEETR-HLDEMKSAMRKGHDLLKKKEEKLIQLESSLQE 1581
Cdd:TIGR02168  928 E---LRLEGLEVrIDNLQERLSEEYSlTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

1066-1582

1.47e-14

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 79.63 E-value: 1.47e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1066 QIRTEQQAALQRLREEAEtLQKAERASLEQKSRRALEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQLEGERKEA 1145
Cdd:pfam02463  177 KLIEETENLAELIIDLEE-LKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1146 VAGLEKKHSAELEQlcSSLEAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAH----QKVHQVTEYEQELSSLLRD 1221
Cdd:pfam02463  256 SKQEIEKEEEKLAQ--VLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVddeeKLKESEKEKKKAEKELKKE 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1222 KRQEVEREHERK-MDKMKEEHWQEMADARERYEAEERKQRADLLGHLTGELERLRRAHERELESMRQEQDQQ----LEDL 1296
Cdd:pfam02463  334 KEEIEELEKELKeLEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKeaqlLLEL 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1297 RRRHRDHERKLQD------LEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEEA---- 1366
Cdd:pfam02463  414 ARQLEDLLKEEKKeeleilEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLlsrq 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1367 KKEHTHLLETKQQ-----LRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNASPHPEP 1441
Cdd:pfam02463  494 KLEERSQKESKARsglkvLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTEL 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1442 GLHIEDLRKSLDTNKNQEVSSSLSLSKEEIDLSMESVRQFLSAEGVAVRNAKEFLVRQTRSMRRRQTALKAAQ--QHWRH 1519
Cdd:pfam02463  574 PLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESglRKGVS 653

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568959107  1520 ELASAQEVDEDLPGTEVLGNMRKN--LNEETRHLDEMKSAMRKGHDLLKKKEEKLIQLESSLQEE 1582
Cdd:pfam02463  654 LEEGLAEKSEVKASLSELTKELLEiqELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLE 718

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

988-1433

2.35e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 78.83 E-value: 2.35e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  988 HWEAQGLDQEEQDDSKSSIAEPQSkhTQGSESLLKAQLQKATAEEKEKEEETKIREEESRRLVCLRAQVQSRTEAFENQI 1067
Cdd:COG1196   384 LAEELLEALRAAAELAAQLEELEE--AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1068 RTEQQAALQRLREEAETLQKAERASLEQKSRR-ALEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQLEGERKEAV 1146
Cdd:COG1196   462 LELLAELLEEAALLEAALAELLEELAEAAARLlLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE 541

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1147 AGLEkkhsAELEQLCSSLEAKHQEVISSLQKKIEGAQqkEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLLRDKRQEV 1226
Cdd:COG1196   542 AALA----AALQNIVVEDDEVAAAAIEYLKAAKAGRA--TFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARY 615

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1227 EREHERKMDKMKEEHWQEMADARERYEAEERKQ--RADLLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDHE 1304
Cdd:COG1196   616 YVLGDTLLGRTLVAARLEAALRRAVTLAGRLREvtLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELEL 695

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1305 RKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEAtathqhLEEAKKEHTHLLETKQQLRRTI 1384
Cdd:COG1196   696 EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL------LEEEALEELPEPPDLEELEREL 769

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 568959107 1385 DDLRVRRVELESqVDLL-----QAQSQRLQkHLSS----LEAEVQRKQDVLKEMAAEM 1433
Cdd:COG1196   770 ERLEREIEALGP-VNLLaieeyEELEERYD-FLSEqredLEEARETLEEAIEEIDRET 825

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

1058-1387

2.92e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 78.96 E-value: 2.92e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1058 SRTEAFENQIRTEQQAALQRLREEAETLqKAERASLEQKSRRaLEQLREQLEAEERSAQAALRAEKEAekeaallqlREQ 1137
Cdd:TIGR02169  659 SRAPRGGILFSRSEPAELQRLRERLEGL-KRELSSLQSELRR-IENRLDELSQELSDASRKIGEIEKE---------IEQ 727

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1138 LEGERKEAVAGLEkkhsaELEQLCSSLEAKHQEVISSLQKKIEGAQQKEE--AQLQESLGWAEQR-AHQKVHQVT----- 1209
Cdd:TIGR02169  728 LEQEEEKLKERLE-----ELEEDLSSLEQEIENVKSELKELEARIEELEEdlHKLEEALNDLEARlSHSRIPEIQaelsk 802

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1210 --EYEQELSSLLRDKRQEVEREHERK--MDKMKEEHWQEMADARERyEAEERKQRADL---------------------- 1263
Cdd:TIGR02169  803 leEEVSRIEARLREIEQKLNRLTLEKeyLEKEIQELQEQRIDLKEQ-IKSIEKEIENLngkkeeleeeleeleaalrdle 881

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1264 --LGHLTGELERLRrAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKA-------RLAQLNVQEEN 1334
Cdd:TIGR02169  882 srLGDLKKERDELE-AQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeeELSLEDVQAEL 960

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 568959107  1335 IRKEKQL--LLDAQRQAALEREEATAThqhLEEAKKEHTHLLETKQQLRRTIDDL 1387
Cdd:TIGR02169  961 QRVEEEIraLEPVNMLAIQEYEEVLKR---LDELKEKRAKLEEERKAILERIEEY 1012

mukB

chromosome partition protein MukB;

1064-1415

1.47e-13

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 76.53 E-value: 1.47e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1064 ENQIRTEQQAaLQRLREEAETLqKAERASLEQksrrALEQLREQLEaeerSAQAALRAEKEAEK-EAALLQLREQLEgER 1142
Cdd:PRK04863  299 RRQLAAEQYR-LVEMARELAEL-NEAESDLEQ----DYQAASDHLN----LVQTALRQQEKIERyQADLEELEERLE-EQ 367

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1143 KEAVAGL--------EKKHSAELEQLC--SSLeAKHQEVISSLQKKIEGAQQKEEAqLQESLGWAeQRAHQKVHQVTEYE 1212
Cdd:PRK04863  368 NEVVEEAdeqqeeneARAEAAEEEVDElkSQL-ADYQQALDVQQTRAIQYQQAVQA-LERAKQLC-GLPDLTADNAEDWL 444

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1213 QELssllRDKRQEVE---REHERKMDkmkeehwqeMAD-ARERYEaeerkQRADLLGHLTGELERLR-----RAHERELE 1283
Cdd:PRK04863  445 EEF----QAKEQEATeelLSLEQKLS---------VAQaAHSQFE-----QAYQLVRKIAGEVSRSEawdvaRELLRRLR 506

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1284 SMRQeQDQQLEDLRRRHRDHERKLQdLEVELSSRTKDVKARLAQ-----LNVQEENIRKEkQLLLDAQRQAALEREEATA 1358
Cdd:PRK04863  507 EQRH-LAEQLQQLRMRLSELEQRLR-QQQRAERLLAEFCKRLGKnlddeDELEQLQEELE-ARLESLSESVSEARERRMA 583

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1359 THQHLEEAKKEHTHL------------------------LETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSS 1414
Cdd:PRK04863  584 LRQQLEQLQARIQRLaarapawlaaqdalarlreqsgeeFEDSQDVTEYMQQLLERERELTVERDELAARKQALDEEIER 663


                  .
gi 568959107 1415 L 1415
Cdd:PRK04863  664 L 664

PRK02224

DNA double-strand break repair Rad50 ATPase;

1071-1582

1.76e-13

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 75.85 E-value: 1.76e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1071 QQAALQRLREEAETLQKAERASLEQKsRRALEQLREQLEA-EERSAQAALraekeAEKEAALLQLREQL---EGERKEAV 1146
Cdd:PRK02224  160 QLGKLEEYRERASDARLGVERVLSDQ-RGSLDQLKAQIEEkEEKDLHERL-----NGLESELAELDEEIeryEEQREQAR 233

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1147 AGLEkkhsaELEQLCSSLEAKHQEvISSLQKKIEGAQQKEEAQLQESLGWAEQrahqkVHQVTEYEQELSSLLRDKRQEV 1226
Cdd:PRK02224  234 ETRD-----EADEVLEEHEERREE-LETLEAEIEDLRETIAETEREREELAEE-----VRDLRERLEELEEERDDLLAEA 302

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1227 ERehERKMDKMKEEHWQEMADARERYEAEERKQRADlLGHLTGELERLR----RAHER--ELESMRQEQDQQLEDLRRRH 1300
Cdd:PRK02224  303 GL--DDADAEAVEARREELEDRDEELRDRLEECRVA-AQAHNEEAESLRedadDLEERaeELREEAAELESELEEAREAV 379

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1301 RDHERKLQDLEVELssrtKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLL------ 1374
Cdd:PRK02224  380 EDRREEIEELEEEI----EELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLeagkcp 455

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1375 ETKQQLR-----RTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAevqrkqdvLKEMAAEmnasphpepglhIEDLR 1449
Cdd:PRK02224  456 ECGQPVEgsphvETIEEDRERVEELEAELEDLEEEVEEVEERLERAED--------LVEAEDR------------IERLE 515

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1450 KSLDTnkNQEVSSSLSLSKEEIDLSMESVR---QFLSAEGVAVRNAKEFLVRQTRSMRRRQTALKAAQQHWRHELASAQE 1526
Cdd:PRK02224  516 ERRED--LEELIAERRETIEEKRERAEELReraAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLER 593

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 568959107 1527 VDEDLPGTEVLGNMRKNLNEETRHLDEMKSAMRkghDLLKKKEEKLIQLESSLQEE 1582
Cdd:PRK02224  594 IRTLLAAIADAEDEIERLREKREALAELNDERR---ERLAEKRERKRELEAEFDEA 646

PTZ00121

MAEBL; Provisional

874-1388

6.40e-13

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 74.41 E-value: 6.40e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  874 KASSSQMAPELDPGGDQPSRASKKQQAEDPVQAGKEGECRRESAAKEPKEASALENTSDVSEESEiHGHLKDARHSGSEA 953
Cdd:PTZ00121 1291 KADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAA-ADEAEAAEEKAEAA 1369

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  954 SGPKSFLGLDLGFRSRISEHLLDGDTLSPVLGGGHWEAQGLDQEEQDDSKSSIAEPQSKHTQGSESLLK-AQLQKATAEE 1032
Cdd:PTZ00121 1370 EKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKkAEEAKKADEA 1449

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1033 KEKeeetkirEEESRRLVCLRAQVQSRTEAFENQIRTEQQAALQRLREEAETL-QKAERASLEQKSRRALEQLReqlEAE 1111
Cdd:PTZ00121 1450 KKK-------AEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAkKKADEAKKAAEAKKKADEAK---KAE 1519

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1112 ERSAQAALRAEKEAEKEAALLQLREQLEGE---RKEAVAGLEKKHSAELEQlcssleaKHQEVISSLQKKIEGAQQKEEA 1188
Cdd:PTZ00121 1520 EAKKADEAKKAEEAKKADEAKKAEEKKKADelkKAEELKKAEEKKKAEEAK-------KAEEDKNMALRKAEEAKKAEEA 1592

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1189 QLQESLGWAEQRAHQKVHQVTEYEQElssllRDKRQEVEREHE--RKMDKMKEEHWQEMADARE-RYEAEERKQRADLLG 1265
Cdd:PTZ00121 1593 RIEEVMKLYEEEKKMKAEEAKKAEEA-----KIKAEELKKAEEekKKVEQLKKKEAEEKKKAEElKKAEEENKIKAAEEA 1667

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1266 HLTGE----LERLRRAHERELESMRQ-----EQDQQLEDLRRRHRDHERKLQDL----EV------ELSSRTKDVKARLA 1326
Cdd:PTZ00121 1668 KKAEEdkkkAEEAKKAEEDEKKAAEAlkkeaEEAKKAEELKKKEAEEKKKAEELkkaeEEnkikaeEAKKEAEEDKKKAE 1747

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568959107 1327 QLNVQEENIRKEKQLLLDAQRQAALEREEATATHQhlEEAKKEHThllETKQQLRRTIDDLR 1388
Cdd:PTZ00121 1748 EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE--EELDEEDE---KRRMEVDKKIKDIF 1804

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

1142-1533

9.85e-13

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 73.94 E-value: 9.85e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1142 RKEAVAGLEK--KHSAELEQLCSSLEAKhqevISSLQKKIEGAQQKEEAQlqeslgwAEQRAHQK---VHQVTEYEQELS 1216
Cdd:TIGR02168  174 RKETERKLERtrENLDRLEDILNELERQ----LKSLERQAEKAERYKELK-------AELRELELallVLRLEELREELE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1217 SLlRDKRQEVEREHERKMDKMKEEHwQEMADAR-ERYEAEERKQradllgHLTGELERLRRAHEReLESMRQEQDQQLED 1295
Cdd:TIGR02168  243 EL-QEELKEAEEELEELTAELQELE-EKLEELRlEVSELEEEIE------ELQKELYALANEISR-LEQQKQILRERLAN 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1296 LRRRHRDHERKLQDLEvelsSRTKDVKARLAQLNVQEENIRKEKQLLLDAqrqaalereeatathqhLEEAKKEHTHLLE 1375
Cdd:TIGR02168  314 LERQLEELEAQLEELE----SKLDELAEELAELEEKLEELKEELESLEAE-----------------LEELEAELEELES 372

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1376 TKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVlkemaaemnasphpepglhIEDLRKSLDTN 1455
Cdd:TIGR02168  373 RLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQE-------------------IEELLKKLEEA 433

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568959107  1456 KNQEVSSSLSLSKEEIDLSMESVRqflsaegvAVRNAKEFLVRQTRSMRRRQTALKAAQQHWRHELASAQEVDEDLPG 1533
Cdd:TIGR02168  434 ELKELQAELEELEEELEELQEELE--------RLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

1070-1432

1.04e-12

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 73.26 E-value: 1.04e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1070 EQQAALQRLREEAETLQKAerasleQKSRRALEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQLEGERKEAVAGL 1149
Cdd:COG4717    75 ELEEELKEAEEKEEEYAEL------QEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERL 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1150 E--KKHSAELEQLCSSLEAKHQEvISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSL---LRDKRQ 1224
Cdd:COG4717   149 EelEERLEELRELEEELEELEAE-LAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAqeeLEELEE 227

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1225 EVEREHERKMDKMKEEHWQEMA-------------------------------------------DARERYEAEERKQRA 1261
Cdd:COG4717   228 ELEQLENELEAAALEERLKEARlllliaaallallglggsllsliltiagvlflvlgllallfllLAREKASLGKEAEEL 307

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1262 DLLGHLTG----ELERLRRAH--------ERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKA------ 1323
Cdd:COG4717   308 QALPALEEleeeELEELLAALglppdlspEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVedeeel 387

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1324 RLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQA 1403
Cdd:COG4717   388 RAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEE 467

                         410       420
                  ....*....|....*....|....*....
gi 568959107 1404 QSQrlqkhLSSLEAEVQRKQDVLKEMAAE 1432
Cdd:COG4717   468 DGE-----LAELLQELEELKAELRELAEE 491

PRK02224

DNA double-strand break repair Rad50 ATPase;

1061-1424

1.11e-12

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 73.54 E-value: 1.11e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1061 EAFENQIRtEQQAALQRLREEAETLqkAERASLEQKSRRALEQLREQLEAEERSAQAALRAEKEAEKeaallQLREQLEG 1140
Cdd:PRK02224  275 EELAEEVR-DLRERLEELEEERDDL--LAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQ-----AHNEEAES 346

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1141 ERKEAvAGLEKKhSAELEQLCSSLEA----------KHQEVISSLQKKIEGAQ--------QKEEAQ-LQESLGWAEQRA 1201
Cdd:PRK02224  347 LREDA-DDLEER-AEELREEAAELESeleeareaveDRREEIEELEEEIEELRerfgdapvDLGNAEdFLEELREERDEL 424

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1202 HQKvhqVTEYEQELSSlLRDKRQEVER-----------------EH----ERKMDKmKEEHWQEMADARERYEA-EERKQ 1259
Cdd:PRK02224  425 RER---EAELEATLRT-ARERVEEAEAlleagkcpecgqpvegsPHvetiEEDRER-VEELEAELEDLEEEVEEvEERLE 499

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1260 RADLLGHLTGELERLRRAHER------ELESMRQEQDQQLEDLRRRHRDHERKLQDLE---VELSSRTKDVKARLAQLNV 1330
Cdd:PRK02224  500 RAEDLVEAEDRIERLEERREDleeliaERRETIEEKRERAEELRERAAELEAEAEEKReaaAEAEEEAEEAREEVAELNS 579

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1331 QEENIRKEKQLLLDAQRQAAlEREEATATHQHLEEAKKehtHLLETKQQLRRTIDDLRVRRVELESQVD-----LLQAQS 1405
Cdd:PRK02224  580 KLAELKERIESLERIRTLLA-AIADAEDEIERLREKRE---ALAELNDERRERLAEKRERKRELEAEFDearieEAREDK 655

                         410
                  ....*....|....*....
gi 568959107 1406 QRLQKHLSSLEAEVQRKQD 1424
Cdd:PRK02224  656 ERAEEYLEQVEEKLDELRE 674

Myosin_tail_1

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

1078-1604

1.13e-12

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 73.67 E-value: 1.13e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1078 LREEAETLQKAERASLEQKSR-RALEQ----LREQLEAEERSAQAALRAEKEAEKEaaLLQLREQLEGErKEAVAGLE-- 1150
Cdd:pfam01576  470 LQDTQELLQEETRQKLNLSTRlRQLEDernsLQEQLEEEEEAKRNVERQLSTLQAQ--LSDMKKKLEED-AGTLEALEeg 546

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1151 -KKHSAELEQLCSSLEAKHQEViSSLQKKIEGAQQKEEAQL-----QESLGWAEQRAHQKVHQVTEYEQELSSLLRDKRQ 1224
Cdd:pfam01576  547 kKRLQRELEALTQQLEEKAAAY-DKLEKTKNRLQQELDDLLvdldhQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERD 625

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1225 EVE---REHERKMDKMKEEhWQEMADARERYEAEERKQRADL---------LGHLTGELERLRRAHERELESMRqEQDQQ 1292
Cdd:pfam01576  626 RAEaeaREKETRALSLARA-LEEALEAKEELERTNKQLRAEMedlvsskddVGKNVHELERSKRALEQQVEEMK-TQLEE 703

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1293 LEDLRRRHRD---------------HERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEA- 1356
Cdd:pfam01576  704 LEDELQATEDaklrlevnmqalkaqFERDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELe 783

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1357 ---TATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVEL-------ESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVL 1426
Cdd:pfam01576  784 aqiDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEIlaqskesEKKLKNLEAELLQLQEDLAASERARRQAQQER 863

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1427 KEMAAEMNASPHPEPGLhiEDLRKSLDT------NKNQEVSSSLSLSKEEIDLSMESVRQF---LSAEGVA---VRNAKE 1494
Cdd:pfam01576  864 DELADEIASGASGKSAL--QDEKRRLEAriaqleEELEEEQSNTELLNDRLRKSTLQVEQLtteLAAERSTsqkSESARQ 941

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1495 FLVRQTRSMRRR--------QTALKAAQQHWRHELASA-----QEVDEDLPGTEVLGNMRKNLNE-------ETRHLDEM 1554
Cdd:pfam01576  942 QLERQNKELKAKlqemegtvKSKFKSSIAALEAKIAQLeeqleQESRERQAANKLVRRTEKKLKEvllqvedERRHADQY 1021

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|
gi 568959107  1555 KSAMRKGHDLLKkkeekliQLESSLqEEVSDEDTLKGSSIKKVTFDLSDM 1604
Cdd:pfam01576 1022 KDQAEKGNSRMK-------QLKRQL-EEAEEEASRANAARRKLQRELDDA 1063

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

1136-1581

3.08e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 72.07 E-value: 3.08e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1136 EQLEGERKEAVAGLEKKHSAELEQLCSsleaKHQEVISSLQKKIEGAQQKEEAqLQESLGWAEQRAHQK----VHQVTEY 1211
Cdd:pfam15921  248 EALKSESQNKIELLLQQHQDRIEQLIS----EHEVEITGLTEKASSARSQANS-IQSQLEIIQEQARNQnsmyMRQLSDL 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1212 EQELSSLlRDKRQEVEREHErkmDKMKEEHWQEMADARERYEAE-ERKQRADLLGHLTGELERL-RRAHERELE-SMRQE 1288
Cdd:pfam15921  323 ESTVSQL-RSELREAKRMYE---DKIEELEKQLVLANSELTEARtERDQFSQESGNLDDQLQKLlADLHKREKElSLEKE 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1289 QDQQLEDlrrRHRDHERKLQDLEVELSSRTKDVKARLAQLNVqeenirkekqllLDAQRQAALEREEAT--ATHQHLEEA 1366
Cdd:pfam15921  399 QNKRLWD---RDTGNSITIDHLRRELDDRNMEVQRLEALLKA------------MKSECQGQMERQMAAiqGKNESLEKV 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1367 KKEHTHLLETKQQLRRTIDDLRVRRVELESQvdllqaqsqrlQKHLSSLEAEVQRKQDVLKEMAAEmnasphpepglhIE 1446
Cdd:pfam15921  464 SSLTAQLESTKEMLRKVVEELTAKKMTLESS-----------ERTVSDLTASLQEKERAIEATNAE------------IT 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1447 DLRKSLDTnKNQEVSSSLSLSK--EEIDLSMESVRQFLSAEGVAVrnakEFLVRQTRSMrrrqtaLKAAQQHWRheLASA 1524
Cdd:pfam15921  521 KLRSRVDL-KLQELQHLKNEGDhlRNVQTECEALKLQMAEKDKVI----EILRQQIENM------TQLVGQHGR--TAGA 587

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 568959107  1525 QEVDEdlpgtevlGNMRKNLNEETRHLDEMKSamrkghdLLKKKEEKLIQLESSLQE 1581
Cdd:pfam15921  588 MQVEK--------AQLEKEINDRRLELQEFKI-------LKDKKDAKIRELEARVSD 629

DUF5401

pfam17380

Family of unknown function (DUF5401); This is a family of unknown function found in ...

1079-1423

3.50e-12

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 71.69 E-value: 3.50e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1079 REEAETLQKAERASLEQKSRRALEQL--REQLEAEERSAQAALRAEKEAEKEaallQLREQLEGERkeavaglekkhsaE 1156
Cdd:pfam17380  287 RQQQEKFEKMEQERLRQEKEEKAREVerRRKLEEAEKARQAEMDRQAAIYAE----QERMAMERER-------------E 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1157 LEQLcsSLEAKHQEVISSLQKKIegAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSsLLRDKRQEVEREHERKMDK 1236
Cdd:pfam17380  350 LERI--RQEERKRELERIRQEEI--AMEISRMRELERLQMERQQKNERVRQELEAARKVK-ILEEERQRKIQQQKVEMEQ 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1237 MkeehwqemadareRYEAEERKQRadllghltgELERLRRAHERELESMRQE-QDQQLEDLRRRHRDHERKLQDLEVEls 1315
Cdd:pfam17380  425 I-------------RAEQEEARQR---------EVRRLEEERAREMERVRLEeQERQQQVERLRQQEEERKRKKLELE-- 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1316 sRTKDVKARLAQLN--VQEENIRKEKQLLLDAQRQAAL------EREEATATHQHLEEAKKEHTHLLETKQqlRRTIDDL 1387
Cdd:pfam17380  481 -KEKRDRKRAEEQRrkILEKELEERKQAMIEEERKRKLlekemeERQKAIYEEERRREAEEERRKQQEMEE--RRRIQEQ 557

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 568959107  1388 RVRRVELESQVDLLQAQSQRLQKhlsSLEAEVQRKQ 1423
Cdd:pfam17380  558 MRKATEERSRLEAMEREREMMRQ---IVESEKARAE 590

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

1054-1370

4.55e-12

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 70.95 E-value: 4.55e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1054 AQVQSRTEAFENQIRT--EQQAALQRLREEAETLQKAERASLEQKSRRALEQLREQLE-AEERSAQAALRAEKEAEKEAA 1130
Cdd:COG4717   142 AELPERLEELEERLEElrELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEeLEELQQRLAELEEELEEAQEE 221

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1131 LLQLREQLEGERKEAVAGLEKKHSAELEQL-------------------------------------CSSLEAKHQEVIS 1173
Cdd:COG4717   222 LEELEEELEQLENELEAAALEERLKEARLLlliaaallallglggsllsliltiagvlflvlgllalLFLLLAREKASLG 301

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1174 SLQKKIEGAQQKEEAQLQESLGWAEQR---AHQKVHQVTEYEQELSSLLRDKRQEVEREHERKMDKMKEE---------- 1240
Cdd:COG4717   302 KEAEELQALPALEELEEEELEELLAALglpPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEiaallaeagv 381

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1241 -------HWQEMADARERYEAEERKQRADLLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVE 1313
Cdd:COG4717   382 edeeelrAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAE 461

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 568959107 1314 LSSRTKDvkARLAQLnvqeeniRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEH 1370
Cdd:COG4717   462 LEQLEED--GELAEL-------LQELEELKAELRELAEEWAALKLALELLEEAREEY 509

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

1091-1433

5.32e-12

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 71.25 E-value: 5.32e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1091 ASLEQKSRRALEQLREQLEAEERsAQAALRAekeaekeaaLLQLREQLEGERKEAV---AGLEKKHSAELEQLCSSLEAk 1167
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIER-LDLIIDE---------KRQQLERLRREREKAEryqALLKEKREYEGYELLKEKEA- 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1168 HQEVISSLQKKIEGaQQKEEAQLQEslgwaeqrahqkvhQVTEYEQELSSLLRDKRQEverehERKMDKMKEEhwqEMAD 1247
Cdd:TIGR02169  235 LERQKEAIERQLAS-LEEELEKLTE--------------EISELEKRLEEIEQLLEEL-----NKKIKDLGEE---EQLR 291

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1248 ARERyeaeerkqradlLGHLTGELERLRRAherelesmrqeqdqqLEDLRRRHRDHERKLQDLEVELSSrtkdVKARLAQ 1327
Cdd:TIGR02169  292 VKEK------------IGELEAEIASLERS---------------IAEKERELEDAEERLAKLEAEIDK----LLAEIEE 340

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1328 LNVQEENIRKEKQLLLDAQRQAALEREEataTHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQR 1407
Cdd:TIGR02169  341 LEREIEEERKRRDKLTEEYAELKEELED---LRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQR 417

                          330       340
                   ....*....|....*....|....*.
gi 568959107  1408 LQKHLSSLEAEVQRKQDVLKEMAAEM 1433
Cdd:TIGR02169  418 LSEELADLNAAIAGIEAKINELEEEK 443

PRK03918

DNA double-strand break repair ATPase Rad50;

1169-1582

9.02e-12

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 70.48 E-value: 9.02e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1169 QEVISSLQKKIEGAQQ--KEEAQLQESLGWAEQRAHQKVHQVteyeQELSSLLRDKRQEVE--REHERKMDKMKEEHwqe 1244
Cdd:PRK03918  168 GEVIKEIKRRIERLEKfiKRTENIEELIKEKEKELEEVLREI----NEISSELPELREELEklEKEVKELEELKEEI--- 240

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1245 madareryeAEERKQRADLLGHLTGELERLR---------RAHERELESMRQEQDQ---------QLEDLRRRHRDHERK 1306
Cdd:PRK03918  241 ---------EELEKELESLEGSKRKLEEKIReleerieelKKEIEELEEKVKELKElkekaeeyiKLSEFYEEYLDELRE 311

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1307 LQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQR------------------QAALEREEATATHQHLEEAKK 1368
Cdd:PRK03918  312 IEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKrleeleerhelyeeakakKEELERLKKRLTGLTPEKLEK 391

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1369 EHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKH-----LSSLEAEVQRKQDVLKEMAAEmnasphpepgl 1443
Cdd:PRK03918  392 ELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAkgkcpVCGRELTEEHRKELLEEYTAE----------- 460

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1444 hIEDLRKSLDTNKNQEVSSSLSLSKEEIDLSMEsvRQFLSAEGVA--VRNAKEFLvrqtrsmrrRQTALKAAQQHWRhel 1521
Cdd:PRK03918  461 -LKRIEKELKEIEEKERKLRKELRELEKVLKKE--SELIKLKELAeqLKELEEKL---------KKYNLEELEKKAE--- 525

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568959107 1522 aSAQEVDEDLPGtevLGNMRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKLIQLESSLQEE 1582
Cdd:PRK03918  526 -EYEKLKEKLIK---LKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEEL 582

PTZ00121

MAEBL; Provisional

1061-1596

1.05e-11

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 70.56 E-value: 1.05e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1061 EAFENQIRTEQQAALQRLREEAETLQKAeRASLEQKSRRALEQLREQLEAEE-RSAQAALRAEkeaekeaallQLREQLE 1139
Cdd:PTZ00121 1082 DAKEDNRADEATEEAFGKAEEAKKTETG-KAEEARKAEEAKKKAEDARKAEEaRKAEDARKAE----------EARKAED 1150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1140 GERKEAVAGLEKKHSAEleqlcsslEAKHQEVisslQKKIEGAQQKEEAQLQESLGWAEQRahQKVHQVTEYEQElssll 1219
Cdd:PTZ00121 1151 AKRVEIARKAEDARKAE--------EARKAED----AKKAEAARKAEEVRKAEELRKAEDA--RKAEAARKAEEE----- 1211

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1220 rDKRQEVER-EHERKMDKMK--EEHWQEMADAR----ERYEAEERKQRADLLGHLTGELERLRRAHERELESMRQ-EQDQ 1291
Cdd:PTZ00121 1212 -RKAEEARKaEDAKKAEAVKkaEEAKKDAEEAKkaeeERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKaEEKK 1290

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1292 QLEDLRRRhrDHERKLQDLE--VELSSRTKDVKARLAQLNVQEENIRKEKQlllDAQRQAALEREEATATHQHLEEAKKE 1369
Cdd:PTZ00121 1291 KADEAKKA--EEKKKADEAKkkAEEAKKADEAKKKAEEAKKKADAAKKKAE---EAKKAAEAAKAEAEAAADEAEAAEEK 1365

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1370 HTHLLETKQQLRRTIDDLRvRRVELESQVDLLQAQSQRLQKHLSSLE--AEVQRKQDVLKEMAaemnasphpepglhiED 1447
Cdd:PTZ00121 1366 AEAAEKKKEEAKKKADAAK-KKAEEKKKADEAKKKAEEDKKKADELKkaAAAKKKADEAKKKA---------------EE 1429

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1448 LRKSLDTNKNQEvsssLSLSKEEIDLSMESVRQflsaegvavrnaKEFLVRQTRSMRRRQTALKAAQQhwrhelasAQEV 1527
Cdd:PTZ00121 1430 KKKADEAKKKAE----EAKKADEAKKKAEEAKK------------AEEAKKKAEEAKKADEAKKKAEE--------AKKA 1485

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568959107 1528 DEdlpgtevlgnMRKNLNEETRHLDEMKSAM--RKGHDLLKKKEEKLIQLESSLQEEVSDEDTLKGSSIKK 1596
Cdd:PTZ00121 1486 DE----------AKKKAEEAKKKADEAKKAAeaKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKK 1546

Myosin_tail_1

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

996-1428

2.40e-11

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 69.05 E-value: 2.40e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107   996 QEEQDDSKSSIAEPQSKHTQGSE--SLLKAQLQKATAEEKEKEEETKIREEESRRLVCLRAQVQSRTEAFE---NQIRTE 1070
Cdd:pfam01576   18 KERQQKAESELKELEKKHQQLCEekNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLEEEEersQQLQNE 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1071 Q-------QAALQRLREEAETLQK--AERASLEQKSRRALEQL-----------REQLEAEERSAQAALRAEKEAEKEAA 1130
Cdd:pfam01576   98 KkkmqqhiQDLEEQLDEEEAARQKlqLEKVTTEAKIKKLEEDIllledqnsklsKERKLLEERISEFTSNLAEEEEKAKS 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1131 LLQLREQLEGERKEAVAGL--EKKHSAELEQLCSSLEAKH---QEVISSLQKKIE---GAQQKEEAQLQESLGWAEQRAH 1202
Cdd:pfam01576  178 LSKLKNKHEAMISDLEERLkkEEKGRQELEKAKRKLEGEStdlQEQIAELQAQIAelrAQLAKKEEELQAALARLEEETA 257

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1203 QK---VHQVTEYEQELSSLLRDkrQEVEREHERKMDKMKEEHWQEMADARERYE---------AEERKQRADLLGHLTGE 1270
Cdd:pfam01576  258 QKnnaLKKIRELEAQISELQED--LESERAARNKAEKQRRDLGEELEALKTELEdtldttaaqQELRSKREQEVTELKKA 335

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1271 LERLRRAHERELESMRQEQDQ-------QLEDLRRRHRDHERKLQDLEVELSSRTKDVKArLAQLNVQEENIRKEkqllL 1343
Cdd:pfam01576  336 LEEETRSHEAQLQEMRQKHTQaleelteQLEQAKRNKANLEKAKQALESENAELQAELRT-LQQAKQDSEHKRKK----L 410

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1344 DAQRQAALEReeatathqhLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESqvdllqaQSQRLQKHLSSLEAEVQRKQ 1423
Cdd:pfam01576  411 EGQLQELQAR---------LSESERQRAELAEKLSKLQSELESVSSLLNEAEG-------KNIKLSKDVSSLESQLQDTQ 474


                   ....*
gi 568959107  1424 DVLKE 1428
Cdd:pfam01576  475 ELLQE 479

SCP-1

pfam05483

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...

1077-1581

2.45e-11

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.

Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 68.98 E-value: 2.45e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1077 RLREEAETLQK---AERASLEQKSRRaLEQLREQLEAEERSAQaalraEKEAEKEAALLQLREQLEgERKEAV------- 1146
Cdd:pfam05483   82 KLYKEAEKIKKwkvSIEAELKQKENK-LQENRKIIEAQRKAIQ-----ELQFENEKVSLKLEEEIQ-ENKDLIkennatr 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1147 --AGLEKKHSAELEQLCSSLEAKHQE---VISSLQKKIEGA--------QQKEEAQLQESLGWAEQraHQKVHQVteyEQ 1213
Cdd:pfam05483  155 hlCNLLKETCARSAEKTKKYEYEREEtrqVYMDLNNNIEKMilafeelrVQAENARLEMHFKLKED--HEKIQHL---EE 229

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1214 ELSSLLRDKRQEVER---EHERKMDKMKE-----EHWQEMADARE---RYEAEERKQRADLLGHLTGELERLRRAHEREL 1282
Cdd:pfam05483  230 EYKKEINDKEKQVSLlliQITEKENKMKDltfllEESRDKANQLEektKLQDENLKELIEKKDHLTKELEDIKMSLQRSM 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1283 ESMR-----------------QEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIrkeKQLLLDA 1345
Cdd:pfam05483  310 STQKaleedlqiatkticqltEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQL---KIITMEL 386

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1346 QRQAAlEREEATATHQH----LEEAKK---EHTHLLETKQQLRRTIDDLRVRRVELesqVDLLQAQSQRLQKHLSSLEAE 1418
Cdd:pfam05483  387 QKKSS-ELEEMTKFKNNkeveLEELKKilaEDEKLLDEKKQFEKIAEELKGKEQEL---IFLLQAREKEIHDLEIQLTAI 462

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1419 VQRKQDVLKEMaAEMNASPHPEPGLHIEdlrksLDTNKNQEVSSSLSLSKEEIDLSMESVRQflSAEGVAVRNAKEFLVR 1498
Cdd:pfam05483  463 KTSEEHYLKEV-EDLKTELEKEKLKNIE-----LTAHCDKLLLENKELTQEASDMTLELKKH--QEDIINCKKQEERMLK 534

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1499 QTRSMRRRQTALKAAQQHWRHEL-ASAQEVDEDLPGTEvlGNMRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKLIQLES 1577
Cdd:pfam05483  535 QIENLEEKEMNLRDELESVREEFiQKGDEVKCKLDKSE--ENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEE 612


                   ....
gi 568959107  1578 SLQE 1581
Cdd:pfam05483  613 LHQE 616

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

1217-1410

4.17e-11

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 67.87 E-value: 4.17e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1217 SLLRDKRQEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRAdlLGHLTGELERLRRAHErELESMRQEQDQQLEDL 1296
Cdd:COG4717    45 AMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEE--YAELQEELEELEEELE-ELEAELEELREELEKL 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1297 RR--RHRDHERKLQDLEVELSS---RTKDVKARLAQLNVQEENIRKEKQLLLDAQRQ-AALEREEATATHQHLEEAKKEH 1370
Cdd:COG4717   122 EKllQLLPLYQELEALEAELAElpeRLEELEERLEELRELEEELEELEAELAELQEElEELLEQLSLATEEELQDLAEEL 201

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 568959107 1371 THLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQK 1410
Cdd:COG4717   202 EELQQRLAELEEELEEAQEELEELEEELEQLENELEAAAL 241

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

1061-1348

4.71e-11

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 68.17 E-value: 4.71e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1061 EAFENQIRT--EQQAALQRLREEAETLQKAERASLEQKSRR-----ALEQLREQLEAEERSAQAALRAEKEAEKEAALlq 1133
Cdd:TIGR02169  240 EAIERQLASleEELEKLTEEISELEKRLEEIEQLLEELNKKikdlgEEEQLRVKEKIGELEAEIASLERSIAEKEREL-- 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1134 lrEQLEGERKEAVAGLEKKhSAELEQLCSSLEAKHQEVIsSLQKKIEGAQQKEEAQLQEsLGWAEQRAHQKVHQVTEYEQ 1213
Cdd:TIGR02169  318 --EDAEERLAKLEAEIDKL-LAEIEELEREIEEERKRRD-KLTEEYAELKEELEDLRAE-LEEVDKEFAETRDELKDYRE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1214 ELSSLLRdKRQEVEREHERKMDKMKEEHwQEMADARERYEAEERKQRAdllghLTGELERLR---RAHERELESMRqeqd 1290
Cdd:TIGR02169  393 KLEKLKR-EINELKRELDRLQEELQRLS-EELADLNAAIAGIEAKINE-----LEEEKEDKAleiKKQEWKLEQLA---- 461

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1291 QQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEK--QLLLDAQRQ 1348
Cdd:TIGR02169  462 ADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRavEEVLKASIQ 521

TPH

pfam13868

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

1070-1422

9.90e-11

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 65.33 E-value: 9.90e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1070 EQQAALQRLREEAETLQKAERASLEQKSRRALEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQLEgERKEAVAGL 1149
Cdd:pfam13868   44 RLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQIEEREQKRQEEYEEKLQEREQMDEIVERIQEE-DQAEAEEKL 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1150 EKKhsaeleqlcsslEAKHQEVISSLQKKIEGAQQKEEAQLQEslgwaEQRAHQKVHQVTEYEQElsslLRDKRQEVERE 1229
Cdd:pfam13868  123 EKQ------------RQLREEIDEFNEEQAEWKELEKEEEREE-----DERILEYLKEKAEREEE----REAEREEIEEE 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1230 HERKMDKMKEEhwQEMAdarERYEAEERKQRADLLghltgELERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQD 1309
Cdd:pfam13868  182 KEREIARLRAQ--QEKA---QDEKAERDELRAKLY-----QEEQERKERQKEREEAEKKARQRQELQQAREEQIELKERR 251

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1310 LEVElssrtkdvkarlaqlnVQEEniRKEKQLLLDAQRQA-ALEREEATATHQHLEEAKKEHTHLLETKQQLRRtiddlR 1388
Cdd:pfam13868  252 LAEE----------------AERE--EEEFERMLRKQAEDeEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRA-----A 308

                          330       340       350
                   ....*....|....*....|....*....|....
gi 568959107  1389 VRRVELESQVDLLQAQSQRLQKhlssLEAEVQRK 1422
Cdd:pfam13868  309 EREEELEEGERLREEEAERRER----IEEERQKK 338

sbcc

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

1093-1581

1.08e-10

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 66.92 E-value: 1.08e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1093 LEQKSRRAleQLREQLEAEERSAQAALRAEKEAEK---EAALLQLREQLEGERKEAVAGLEKKHSAELEQLCSSL-EAKH 1168
Cdd:TIGR00618  159 KAKSKEKK--ELLMNLFPLDQYTQLALMEFAKKKSlhgKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLrEALQ 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1169 QEVISSLQKKIEGAQQKEEAQLQESLGWA-----EQRAHQKVHQVTEYEQELS-------------SLLRDKRQEVEREH 1230
Cdd:TIGR00618  237 QTQQSHAYLTQKREAQEEQLKKQQLLKQLrarieELRAQEAVLEETQERINRArkaaplaahikavTQIEQQAQRIHTEL 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1231 ERKMDKMKEEHWQEMADARERYEAEERKQradLLGHLTGELERLRRAHERELeSMRQEQDQQLEDLRRRHRDHERK--LQ 1308
Cdd:TIGR00618  317 QSKMRSRAKLLMKRAAHVKQQSSIEEQRR---LLQTLHSQEIHIRDAHEVAT-SIREISCQQHTLTQHIHTLQQQKttLT 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1309 DLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEE----AKKEHTHLLETKQQLRRTI 1384
Cdd:TIGR00618  393 QKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCtaqcEKLEKIHLQESAQSLKERE 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1385 DDLRVRRVELESQVDLLQAQSQRLQKHlSSLEAEVQRKqdvLKEMAAEMNASPHPEPglhiedlrkslDTNKNQEVSSSL 1464
Cdd:TIGR00618  473 QQLQTKEQIHLQETRKKAVVLARLLEL-QEEPCPLCGS---CIHPNPARQDIDNPGP-----------LTRRMQRGEQTY 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1465 SLSKEEIdlsmESVRqflsAEGVAVRNAKEFLVRQTRSMrrRQTALKAAQQHwrhelasaQEVDEDLPGTevlgnmrKNL 1544
Cdd:TIGR00618  538 AQLETSE----EDVY----HQLTSERKQRASLKEQMQEI--QQSFSILTQCD--------NRSKEDIPNL-------QNI 592

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|..
gi 568959107  1545 NEETRHLDEMKSAMRK-----GHDLLKKKEEKLIQLESSLQE 1581
Cdd:TIGR00618  593 TVRLQDLTEKLSEAEDmlaceQHALLRKLQPEQDLQDVRLHL 634

DUF5401

pfam17380

Family of unknown function (DUF5401); This is a family of unknown function found in ...

1210-1429

1.20e-10

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 66.69 E-value: 1.20e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1210 EYEQELSSLLRDKRQEVEREHERKMDKM--------KEEHWQEMADARERYEAEERKQRA-DLLGHLTGELERLRRAHER 1280
Cdd:pfam17380  269 EFLNQLLHIVQHQKAVSERQQQEKFEKMeqerlrqeKEEKAREVERRRKLEEAEKARQAEmDRQAAIYAEQERMAMERER 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1281 ELESMRQEQ-DQQLEDLRRRHRDHE----RKLQDLEVELSSRTKDVKARLaqlnvqeENIRKEKQLLLDAQRQAALEREE 1355
Cdd:pfam17380  349 ELERIRQEErKRELERIRQEEIAMEisrmRELERLQMERQQKNERVRQEL-------EAARKVKILEEERQRKIQQQKVE 421

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568959107  1356 ATATHQHLEEAKKEHTHLLETKQQlrRTIDdlRVRRVELE--SQVDLLQAQSQRLQKHLSSLEAEvQRKQDVLKEM 1429
Cdd:pfam17380  422 MEQIRAEQEEARQREVRRLEEERA--REME--RVRLEEQErqQQVERLRQQEEERKRKKLELEKE-KRDRKRAEEQ 492

MAD

pfam05557

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...

1053-1595

1.36e-10

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.

Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 66.30 E-value: 1.36e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1053 RAQVQSRTEAFENQIRTEQQAALQRLREEAETLQKAERAS--LEQKSRRALEQLR--EQLEAEERSAQAALRAEKEaeke 1128
Cdd:pfam05557    1 RAELIESKARLSQLQNEKKQMELEHKRARIELEKKASALKrqLDRESDRNQELQKriRLLEKREAEAEEALREQAE---- 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1129 aallqlREQLEGERKEAVAGLEKKHSAELEQLCSSLEAKHQEvISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKvHQV 1208
Cdd:pfam05557   77 ------LNRLKKKYLEALNKKLNEKESQLADAREVISCLKNE-LSELRRQIQRAELELQSTNSELEELQERLDLLK-AKA 148

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1209 TEYEQELSSLlrDKRQEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRadlLGHLTGELERLRR--AHERELESMR 1286
Cdd:pfam05557  149 SEAEQLRQNL--EKQQSSLAEAEQRIKELEFEIQSQEQDSEIVKNSKSELAR---IPELEKELERLREhnKHLNENIENK 223

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1287 QEQDQQLEDLRR---RHRDHERKLQDLEVELSSRTKDVKA--RLAQ-----LNVQEENIRKEKQLLldaQRQAALEREEA 1356
Cdd:pfam05557  224 LLLKEEVEDLKRkleREEKYREEAATLELEKEKLEQELQSwvKLAQdtglnLRSPEDLSRRIEQLQ---QREIVLKEENS 300

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1357 TATHQ--HLEEAKKEhthLLETKQQLRRTIDDLRVRRVELESQVDllqaqsqRLQKHLSSLEAEVQRKQDVLKEMAAEMN 1434
Cdd:pfam05557  301 SLTSSarQLEKARRE---LEQELAQYLKKIEDLNKKLKRHKALVR-------RLQRRVLLLTKERDGYRAILESYDKELT 370

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1435 ASPH-PEPGLHIEDLRKSLD--TNKNQEVSSSLSLSKEEI----------DLSMESVRQ-------FLSAEGV-AVRNAK 1493
Cdd:pfam05557  371 MSNYsPQLLERIEEAEDMTQkmQAHNEEMEAQLSVAEEELggykqqaqtlERELQALRQqesladpSYSKEEVdSLRRKL 450

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1494 EFLVRQTRSMRRRQTALKAaqQHWRHELASaqevDEDLPGTEVLgNMRKNLNEETRhldEMKSAMrkgHDLLKKKEEKLI 1573
Cdd:pfam05557  451 ETLELERQRLREQKNELEM--ELERRCLQG----DYDPKKTKVL-HLSMNPAAEAY---QQRKNQ---LEKLQAEIERLK 517

                          570       580
                   ....*....|....*....|..
gi 568959107  1574 QLESSLQEEVSDEDTLKGSSIK 1595
Cdd:pfam05557  518 RLLKKLEDDLEQVLRLPETTST 539

DUF3584

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

1052-1460

2.14e-10

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 66.02 E-value: 2.14e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1052 LRAQVQSRTEAFENQIRTEQQAALQRLREEAETLQ-KAERASLEQKSRRALEQLREQLEAEERSAQAALRAEKEAEKEAA 1130
Cdd:pfam12128  409 QLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKsRLGELKLRLNQATATPELLLQLENFDERIERAREEQEAANAEVE 488

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1131 LLQLRE-QLEGERKEAVAGLEKKHSAeLEQLCSSLEAKHQEVISSLQKKIEgAQQKEEAQLQESLGW---AEQRAHQKVH 1206
Cdd:pfam12128  489 RLQSELrQARKRRDQASEALRQASRR-LEERQSALDELELQLFPQAGTLLH-FLRKEAPDWEQSIGKvisPELLHRTDLD 566

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1207 QVTEYEQELSSL------LRDKRQEV------EREHERKMDKMKEehwqEMADARERYEAEERKqradlLGHLTGELERL 1274
Cdd:pfam12128  567 PEVWDGSVGGELnlygvkLDLKRIDVpewaasEEELRERLDKAEE----ALQSAREKQAAAEEQ-----LVQANGELEKA 637

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1275 RRAHERELES--------------MRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQ 1340
Cdd:pfam12128  638 SREETFARTAlknarldlrrlfdeKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQ 717

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1341 LL-----------LDAQRQAALEREEATATHQ-------HLEEAKK--EHTHLLETKQQLR---RTIDDLRVRRVELESQ 1397
Cdd:pfam12128  718 AYwqvvegaldaqLALLKAAIAARRSGAKAELkaletwyKRDLASLgvDPDVIAKLKREIRtleRKIERIAVRRQEVLRY 797

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568959107  1398 VDLLQA----QSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNasphpepgLHIEDLRKSLDTNKNQEV 1460
Cdd:pfam12128  798 FDWYQEtwlqRRPRLATQLSNIERAISELQQQLARLIADTK--------LRRAKLEMERKASEKQQV 856

Mplasa_alph_rch

TIGR04523

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...

1131-1597

2.65e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.

Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 65.43 E-value: 2.65e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1131 LLQLREQLEgERKEAVAGLEKKHSAeLEQLCSSLEAKHQEvISSLQKKIEGAQQKEEaQLQESLGWAEQRAHQKVHQVTE 1210
Cdd:TIGR04523  175 LNLLEKEKL-NIQKNIDKIKNKLLK-LELLLSNLKKKIQK-NKSLESQISELKKQNN-QLKDNIEKKQQEINEKTTEISN 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1211 YEQELSSLLrDKRQEVEREHERKMdkmkeehwqemadareryeaEERKQRADLLGHLTGELERLrrahERELESMRQEQD 1290
Cdd:TIGR04523  251 TQTQLNQLK-DEQNKIKKQLSEKQ--------------------KELEQNNKKIKELEKQLNQL----KSEISDLNNQKE 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1291 QQL-EDLRRRHRDHERKLQDLEVELSSRTKdvkaRLAQLNVQEENIRKEKQlllDAQRQAALEREEATATHQHLEEAKKE 1369
Cdd:TIGR04523  306 QDWnKELKSELKNQEKKLEEIQNQISQNNK----IISQLNEQISQLKKELT---NSESENSEKQRELEEKQNEIEKLKKE 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1370 HTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRkqdvLKEMAAEMNASphpepglhIEDLR 1449
Cdd:TIGR04523  379 NQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIER----LKETIIKNNSE--------IKDLT 446

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1450 KSlDTNKNQEVssslslskEEIDLSMESVRQFLSAegvavrnakeflvrQTRSMRRRQTALKAAQQhwrhELASAQevde 1529
Cdd:TIGR04523  447 NQ-DSVKELII--------KNLDNTRESLETQLKV--------------LSRSINKIKQNLEQKQK----ELKSKE---- 495

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568959107  1530 dlpgtevlgNMRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKL------IQLE-SSLQEEV-SDEDTLKGSSIKKV 1597
Cdd:TIGR04523  496 ---------KELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLesekkeKESKiSDLEDELnKDDFELKKENLEKE 562

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

1224-1432

3.27e-10

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 64.01 E-value: 3.27e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1224 QEVEREHERKMDKMKeehwQEMADARERYEAEERKQRAdllghLTGELERLRRAhERELESMRQEQDQQLEDLRRRHRDH 1303
Cdd:COG4942    19 ADAAAEAEAELEQLQ----QEIAELEKELAALKKEEKA-----LLKQLAALERR-IAALARRIRALEQELAALEAELAEL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1304 ERKLQDLEVELSSRTKDVKARLAQLnvQEENIRKEKQLLL------DAQRQAALEREEATATHQHLEEAKKEHTHLLETK 1377
Cdd:COG4942    89 EKEIAELRAELEAQKEELAELLRAL--YRLGRQPPLALLLspedflDAVRRLQYLKYLAPARREQAEELRADLAELAALR 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 568959107 1378 QQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAE 1432
Cdd:COG4942   167 AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

1160-1578

4.26e-10

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 64.79 E-value: 4.26e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1160 LCSSLEAKHQEvISSLQKKIEGAQQKEEAQLQESLGWAEQRaHQKVHQVTEYEQELSSLLRDKRQEVE--REHERKMDKM 1237
Cdd:COG4717    47 LLERLEKEADE-LFKPQGRKPELNLKELKELEEELKEAEEK-EEEYAELQEELEELEEELEELEAELEelREELEKLEKL 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1238 KE--EHWQEMADAR-------ERYEA-----EERKQRADLLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDH 1303
Cdd:COG4717   125 LQllPLYQELEALEaelaelpERLEEleerlEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEEL 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1304 ERKLQDLEVELssrtKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALERE--------EATATHQHLEEAKKEHTHLLE 1375
Cdd:COG4717   205 QQRLAELEEEL----EEAQEELEELEEELEQLENELEAAALEERLKEARLLlliaaallALLGLGGSLLSLILTIAGVLF 280

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1376 TKQQLRrTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEaevqrkqdvLKEMAAEMNASPHPEPGlHIEDLRKSLDTN 1455
Cdd:COG4717   281 LVLGLL-ALLFLLLAREKASLGKEAEELQALPALEELEEEE---------LEELLAALGLPPDLSPE-ELLELLDRIEEL 349

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1456 KNQEVSSSLSLSKEEIDLSMESVRQFLSAEGVAvrNAKEFLVRQTRSmrRRQTALKAAQQHWRHELASAQEVDEDLPGTE 1535
Cdd:COG4717   350 QELLREAEELEEELQLEELEQEIAALLAEAGVE--DEEELRAALEQA--EEYQELKEELEELEEQLEELLGELEELLEAL 425

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 568959107 1536 VLGNMRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKLIQLESS 1578
Cdd:COG4717   426 DEEELEEELEELEEELEELEEELEELREELAELEAELEQLEED 468

sbcc

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

1052-1591

5.20e-10

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 64.60 E-value: 5.20e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1052 LRAQVQSRTEAF-ENQIRTEQQAALQRLREEAETLQKAE----RASLEQKSRRA-----------LEQLREQLEAEERSA 1115
Cdd:TIGR00618  316 LQSKMRSRAKLLmKRAAHVKQQSSIEEQRRLLQTLHSQEihirDAHEVATSIREiscqqhtltqhIHTLQQQKTTLTQKL 395

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1116 QAAlraekeaekEAALLQLREQlegerkeaVAGLEKKHSAELEQLCSSLEAKHQEVISSLQKKIEGAQQKEEAQLQESLG 1195
Cdd:TIGR00618  396 QSL---------CKELDILQRE--------QATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEK 458

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1196 WAEQRAHQKVHQVTEYEQELSSLLRdKRQEVEREHERKMDKMKEEhwQEMADARERYEAEERKQrADLLGHLTGELERL- 1274
Cdd:TIGR00618  459 IHLQESAQSLKEREQQLQTKEQIHL-QETRKKAVVLARLLELQEE--PCPLCGSCIHPNPARQD-IDNPGPLTRRMQRGe 534

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1275 --RRAHERELESMRQEQDQQLEDlRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALE 1352
Cdd:TIGR00618  535 qtYAQLETSEEDVYHQLTSERKQ-RASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACE 613

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1353 reeatathQHLEEAKKEHT-HLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAE--VQRKQDVLKEM 1429
Cdd:TIGR00618  614 --------QHALLRKLQPEqDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKelLASRQLALQKM 685

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1430 AAEMNASPHPEPGL-HIEDLRKSLDTnknqeVSSSLSLSKEEIDLSMESVRQFLSAEGVAVRNAkeflvrQTRSMRRRQT 1508
Cdd:TIGR00618  686 QSEKEQLTYWKEMLaQCQTLLRELET-----HIEEYDREFNEIENASSSLGSDLAAREDALNQS------LKELMHQART 754

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1509 ALKAaqQHWRHELASAQEVDEDLPGTEV------LGNMRKNLNEETRHLDEMKSAMRK----GHDLLKKKEEKLIQLESS 1578
Cdd:TIGR00618  755 VLKA--RTEAHFNNNEEVTAALQTGAELshlaaeIQFFNRLREEDTHLLKTLEAEIGQeipsDEDILNLQCETLVQEEEQ 832

                          570
                   ....*....|...
gi 568959107  1579 LQEEVSDEDTLKG 1591
Cdd:TIGR00618  833 FLSRLEEKSATLG 845

COG4372

Uncharacterized protein, contains DUF3084 domain [Function unknown];

1255-1514

6.21e-10

Uncharacterized protein, contains DUF3084 domain [Function unknown];

Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 63.38 E-value: 6.21e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1255 EERKQRADLLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEEN 1334
Cdd:COG4372     9 GKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQ 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1335 IRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSS 1414
Cdd:COG4372    89 LQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAA 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1415 LEAEVQRKQDVLKEMAAEMNASPHPEPGLHIEDLRKSLDTNKNQEVSSSLSLSKEEIDLSMESVRQFLSAEGVAVRNAKE 1494
Cdd:COG4372   169 LEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDK 248

                         250       260
                  ....*....|....*....|
gi 568959107 1495 FLVRQTRSMRRRQTALKAAQ 1514
Cdd:COG4372   249 EELLEEVILKEIEELELAIL 268

DUF5401

pfam17380

Family of unknown function (DUF5401); This is a family of unknown function found in ...

1055-1342

6.47e-10

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 64.37 E-value: 6.47e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1055 QVQSRTEAFENQ-IRTEQQAALQRL--REEAETLQKAERASLEQKS-------RRALEQLRE--QLEAEERSAQAALRAE 1122
Cdd:pfam17380  288 QQQEKFEKMEQErLRQEKEEKAREVerRRKLEEAEKARQAEMDRQAaiyaeqeRMAMEREREleRIRQEERKRELERIRQ 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1123 KEAEKEAALLQLREQLEGERKEAVAGLEKKHSAELEQlcSSLEAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAH 1202
Cdd:pfam17380  368 EEIAMEISRMRELERLQMERQQKNERVRQELEAARKV--KILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERA 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1203 QKVHQVTEYEQELSSLLRDKRQEVEREHERKMDKMKEEHWQEMADARERY----EAEERKQRADllghltgELERLRRAH 1278
Cdd:pfam17380  446 REMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKilekELEERKQAMI-------EEERKRKLL 518

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568959107  1279 ERELEsmrQEQDQQLEDLRRRHRDHERKLQdLEVELSSRTKDVKARLAQLNVQEENIRKEKQLL 1342
Cdd:pfam17380  519 EKEME---ERQKAIYEEERRREAEEERRKQ-QEMEERRRIQEQMRKATEERSRLEAMEREREMM 578

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

1219-1422

6.57e-10

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 63.24 E-value: 6.57e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1219 LRDKRQEVEREHERKMDKMKEEHWQEMADARERYEAEER-KQRADLLGHLTGELERLRR---AHERELESMRQEQDQQLE 1294
Cdd:COG4942    25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRiAALARRIRALEQELAALEAelaELEKEIAELRAELEAQKE 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1295 DLRRRHRDHER--KLQDLEVELSS--------RTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLE 1364
Cdd:COG4942   105 ELAELLRALYRlgRQPPLALLLSPedfldavrRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELE 184

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 568959107 1365 EAKKEhthLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRK 1422
Cdd:COG4942   185 EERAA---LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

994-1600

9.13e-10

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 63.93 E-value: 9.13e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107   994 LDQEEQDDSKSSIAEPQSK--HTQGSESLLKAQLQkataeekekeeetkIREEESRRLVCLRAQVQSRTEAFENQIRTEQ 1071
Cdd:TIGR02169  284 LGEEEQLRVKEKIGELEAEiaSLERSIAEKERELE--------------DAEERLAKLEAEIDKLLAEIEELEREIEEER 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1072 ------QAALQRLREEAETLqkaeRASLEQKSRRALEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQLEGER--- 1142
Cdd:TIGR02169  350 krrdklTEEYAELKEELEDL----RAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELadl 425

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1143 KEAVAGLEKKHS---AELEQLCSSLEAKHQEvISSLQKKIEGAQQ-------------KEEAQLQESLGWAEQRAHQKVH 1206
Cdd:TIGR02169  426 NAAIAGIEAKINeleEEKEDKALEIKKQEWK-LEQLAADLSKYEQelydlkeeydrveKELSKLQRELAEAEAQARASEE 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1207 QVTEYeQELSSLLRDKRQ----------EVEREH-------------------------------ERK--------MDKM 1237
Cdd:TIGR02169  505 RVRGG-RAVEEVLKASIQgvhgtvaqlgSVGERYataievaagnrlnnvvveddavakeaiellkRRKagratflpLNKM 583

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1238 KEEH--------------------------------------WQEMADARE----------------------------- 1250
Cdd:TIGR02169  584 RDERrdlsilsedgvigfavdlvefdpkyepafkyvfgdtlvVEDIEAARRlmgkyrmvtlegelfeksgamtggsrapr 663

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1251 ------RYEAEERKQRADLLGHLTGELERLrRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVE---LSSRTKDV 1321
Cdd:TIGR02169  664 ggilfsRSEPAELQRLRERLEGLKRELSSL-QSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEeekLKERLEEL 742

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1322 KARLAQLNVQEENIRKEKQLLldaqrQAALEREEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLL 1401
Cdd:TIGR02169  743 EEDLSSLEQEIENVKSELKEL-----EARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREI 817

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1402 QAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNasphpEPGLHIEDLRKSLDtNKNQEVSSSLSL----SKEEIDLSMEs 1477
Cdd:TIGR02169  818 EQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIK-----SIEKEIENLNGKKE-ELEEELEELEAAlrdlESRLGDLKKE- 890

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1478 vRQFLSAEGVAVRNAKEFLVRQTRSMRRRQTALKAAQQHWRHELA-------SAQEVDEDLPGTEVLGNMRKNLNEETRH 1550
Cdd:TIGR02169  891 -RDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSeiedpkgEDEEIPEEELSLEDVQAELQRVEEEIRA 969

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 568959107  1551 L--------DEMKSAMRKgHDLLKKKEEKLIQLESSLQEEVSDEDTLKGSSIKKvTFD 1600
Cdd:TIGR02169  970 LepvnmlaiQEYEEVLKR-LDELKEKRAKLEEERKAILERIEEYEKKKREVFME-AFE 1025

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

1059-1347

1.42e-09

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.54 E-value: 1.42e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1059 RTEAFENQIRT--EQQAALQRLREEAETLQKAERASLEQksrraLEQLREQLEAEERSAQAALRAEKEAEKEaalLQLRE 1136
Cdd:TIGR02168  233 RLEELREELEElqEELKEAEEELEELTAELQELEEKLEE-----LRLEVSELEEEIEELQKELYALANEISR---LEQQK 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1137 QLEGERKEAVAGLEKKHSAELEQLCSSLE------AKHQEVISSLQKKIEGAQQKEEAqLQESLGWAEQRAHQKVHQVTE 1210
Cdd:TIGR02168  305 QILRERLANLERQLEELEAQLEELESKLDelaeelAELEEKLEELKEELESLEAELEE-LEAELEELESRLEELEEQLET 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1211 YEQELSSLLRdkRQEVEREHERKMDKMKEehwqEMADARERYEAEERKQRADLLGHLTGELERLRRAHERELESMRQEQD 1290
Cdd:TIGR02168  384 LRSKVAQLEL--QIASLNNEIERLEARLE----RLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELE 457

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568959107  1291 ---QQLEDLRRRHRDHERKLQDLEVELSSrtkdVKARLAQLNVQEENIRKE----KQLLLDAQR 1347
Cdd:TIGR02168  458 rleEALEELREELEEAEQALDAAERELAQ----LQARLDSLERLQENLEGFsegvKALLKNQSG 517

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

1047-1329

1.52e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 63.40 E-value: 1.52e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1047 RRLVCLRAQVQSRTEAFE--NQIRTEQQAALQRLREEAETLQKAERASLEQKSRRALEQLREQLEAEERSAQAAlraeke 1124
Cdd:COG4913   610 AKLAALEAELAELEEELAeaEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDAS------ 683

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1125 aekEAALLQLREQLEgERKEAVAGLEKKHsAELEQLCSSLEAKH---QEVISSLQKKIEGAQQKEEAQLQESLgwaEQRA 1201
Cdd:COG4913   684 ---SDDLAALEEQLE-ELEAELEELEEEL-DELKGEIGRLEKELeqaEEELDELQDRLEAAEDLARLELRALL---EERF 755

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1202 HQkvHQVTEYEQELSSLLRDKRQEVEREHERKMDKMKEehwqEMADARERYEAEERKQRADL--LGHLTGELERLR---- 1275
Cdd:COG4913   756 AA--ALGDAVERELRENLEERIDALRARLNRAEEELER----AMRAFNREWPAETADLDADLesLPEYLALLDRLEedgl 829

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 568959107 1276 -RAHERELESMRQEQDQQLEDLRRRHRDHERklqdlevelssrtkDVKARLAQLN 1329
Cdd:COG4913   830 pEYEERFKELLNENSIEFVADLLSKLRRAIR--------------EIKERIDPLN 870

DR0291

COG1579

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

1245-1435

2.26e-09

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 59.94 E-value: 2.26e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1245 MADARERYEAEERKQRADLLGHLTGELERLRRAHERELESMRQEqdqqLEDLRRRHRDHERKLQDLEVELssrtKDVKAR 1324
Cdd:COG1579     3 PEDLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEAR----LEAAKTELEDLEKEIKRLELEI----EEVEAR 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1325 LAQLNVQEENIRKEKQLlldaqrqAALEREEATATHQhLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAq 1404
Cdd:COG1579    75 IKKYEEQLGNVRNNKEY-------EALQKEIESLKRR-ISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKA- 145

                         170       180       190
                  ....*....|....*....|....*....|.
gi 568959107 1405 sqRLQKHLSSLEAEVQRKQDVLKEMAAEMNA 1435
Cdd:COG1579   146 --ELDEELAELEAELEELEAEREELAAKIPP 174

PRK12704

phosphodiesterase; Provisional

1231-1372

2.68e-09

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 61.72 E-value: 2.68e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1231 ERKMDKMKEEHWQEMADAREryEAEERKQRADLlgHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDL 1310
Cdd:PRK12704   30 EAKIKEAEEEAKRILEEAKK--EAEAIKKEALL--EAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELL 105

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568959107 1311 ---EVELSSRTKDVKARLAQLNVQEENI-RKEKQLLLDAQRQAALEREEATAthQHLEEAKKEHTH 1372
Cdd:PRK12704  106 ekrEEELEKKEKELEQKQQELEKKEEELeELIEEQLQELERISGLTAEEAKE--ILLEKVEEEARH 169

PRK02224

DNA double-strand break repair Rad50 ATPase;

1053-1332

3.41e-09

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 61.98 E-value: 3.41e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1053 RAQVQSRTEAFENQIRT-----EQQAALQRLREEAETLQK---AERASLEQKSRRAlEQLREQL-----EAEERSAQAAl 1119
Cdd:PRK02224  484 LEDLEEEVEEVEERLERaedlvEAEDRIERLEERREDLEEliaERRETIEEKRERA-EELRERAaeleaEAEEKREAAA- 561

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1120 raekeaekeaallQLREQLEGERkEAVAGLEKKhsaeLEQLCSSLEAkhQEVISSLQKKIEgaqqkeeaqlqeslgwaeq 1199
Cdd:PRK02224  562 -------------EAEEEAEEAR-EEVAELNSK----LAELKERIES--LERIRTLLAAIA------------------- 602

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1200 rahqkvhqvtEYEQELSSlLRDKRQEV-EREHERKmDKMKE--EHWQEMADA--RERYE-AEERKQRA-DLLGHLTGELE 1272
Cdd:PRK02224  603 ----------DAEDEIER-LREKREALaELNDERR-ERLAEkrERKRELEAEfdEARIEeAREDKERAeEYLEQVEEKLD 670

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568959107 1273 RLrRAHERELES---MRQEQDQQLEDLRRRHRDHERKLQDLEV------ELSSRTKDVKARLAQLNVQE 1332
Cdd:PRK02224  671 EL-REERDDLQAeigAVENELEELEELRERREALENRVEALEAlydeaeELESMYGDLRAELRQRNVET 738

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

1046-1417

4.91e-09

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 61.89 E-value: 4.91e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1046 SRRLVCLRAQVQSRTEAFENQ-IRTEQQAALQRLREEAETLQKAERAsLEQKSRRALEQLREqleaeersAQAALRAEKE 1124
Cdd:COG3096   278 NERRELSERALELRRELFGARrQLAEEQYRLVEMARELEELSARESD-LEQDYQAASDHLNL--------VQTALRQQEK 348

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1125 -AEKEAALLQLREQLEgERKEAVAGL--------EKKHSAELE--QLCSSLeAKHQEVISSLQKKIEGAQQ----KEEAQ 1189
Cdd:COG3096   349 iERYQEDLEELTERLE-EQEEVVEEAaeqlaeaeARLEAAEEEvdSLKSQL-ADYQQALDVQQTRAIQYQQavqaLEKAR 426

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1190 LQ---ESLGWAEQRAHQKVHQvtEYEQELSSLLRDKRQEVE------REHERKMdkmkeEHWQEMADARERYEAEERKQ- 1259
Cdd:COG3096   427 ALcglPDLTPENAEDYLAAFR--AKEQQATEEVLELEQKLSvadaarRQFEKAY-----ELVCKIAGEVERSQAWQTARe 499

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1260 ---RADLLGHLTGELERLRRAH---ERELESmRQEQDQQLEDLRRRH---RDHERKLQDLEVELSSRTKDVKARLAqlNV 1330
Cdd:COG3096   500 llrRYRSQQALAQRLQQLRAQLaelEQRLRQ-QQNAERLLEEFCQRIgqqLDAAEELEELLAELEAQLEELEEQAA--EA 576

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1331 QEENIRKEKQLLLDAQRQAALEREE-----ATATHQHLEEAKKEHthlLETKQQLRRTIDDLRVRRVELESQVDLLQAQS 1405
Cdd:COG3096   577 VEQRSELRQQLEQLRARIKELAARApawlaAQDALERLREQSGEA---LADSQEVTAAMQQLLEREREATVERDELAARK 653

                         410
                  ....*....|..
gi 568959107 1406 QRLQKHLSSLEA 1417
Cdd:COG3096   654 QALESQIERLSQ 665

DUF3584

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

1083-1387

6.87e-09

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 61.01 E-value: 6.87e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1083 ETLQKAERASLEQKSRRALEQLREQLEAEERSAQAAlraekeaekEAALLQLREQLEGERKEAVAGLEKKHSAELEQlcS 1162
Cdd:pfam12128  588 KRIDVPEWAASEEELRERLDKAEEALQSAREKQAAA---------EEQLVQANGELEKASREETFARTALKNARLDL--R 656

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1163 SLEAKHQEVISSLQKKIEGAQQKEEAQLQESLgwAEQRAHQKVHQVTEYEQ-----ELSSLLRDKRQEVEREHERKMDKM 1237
Cdd:pfam12128  657 RLFDEKQSEKDKKNKALAERKDSANERLNSLE--AQLKQLDKKHQAWLEEQkeqkrEARTEKQAYWQVVEGALDAQLALL 734

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1238 KEE--HWQEMADARERYEAEERKQRADLLG--------------HLTGELERL--RRAHERELESMRQEQ-DQQLEDLRR 1298
Cdd:pfam12128  735 KAAiaARRSGAKAELKALETWYKRDLASLGvdpdviaklkreirTLERKIERIavRRQEVLRYFDWYQETwLQRRPRLAT 814

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1299 RHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQR--QAALEREEATATHQHLEEAKKEHTHLLET 1376
Cdd:pfam12128  815 QLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRglRCEMSKLATLKEDANSEQAQGSIGERLAQ 894

                          330
                   ....*....|.
gi 568959107  1377 KQQLRRTIDDL 1387
Cdd:pfam12128  895 LEDLKLKRDYL 905

PRK03918

DNA double-strand break repair ATPase Rad50;

1058-1577

1.29e-08

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 60.08 E-value: 1.29e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1058 SRTEAFENQIRTEQQ---AALQRLREEAETLQK--AERASLEQKSRRaLEQLREQLEAEERsaQAALRAEKEAEKEAALL 1132
Cdd:PRK03918  186 KRTENIEELIKEKEKeleEVLREINEISSELPElrEELEKLEKEVKE-LEELKEEIEELEK--ELESLEGSKRKLEEKIR 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1133 QLREQLEGERKEaVAGLEKKhSAELEQLcsSLEAKHQEVISSLQKKIEgaqqKEEAQLQESLGWAEQRAHQKVHQVTEYE 1212
Cdd:PRK03918  263 ELEERIEELKKE-IEELEEK-VKELKEL--KEKAEEYIKLSEFYEEYL----DELREIEKRLSRLEEEINGIEERIKELE 334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1213 QELSSL--LRDKRQEVEREHERkmdkMKEEHwQEMADARERYEAEER--KQRADL-LGHLTGELERLRRAHE------RE 1281
Cdd:PRK03918  335 EKEERLeeLKKKLKELEKRLEE----LEERH-ELYEEAKAKKEELERlkKRLTGLtPEKLEKELEELEKAKEeieeeiSK 409

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1282 LESMRQEQDQQLEDLR-----------------RRHRDHERKlqDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLld 1344
Cdd:PRK03918  410 ITARIGELKKEIKELKkaieelkkakgkcpvcgRELTEEHRK--ELLEEYTAELKRIEKELKEIEEKERKLRKELREL-- 485

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1345 aqRQAALEREEATATHQHLEEAKkehthllETKQQLRR-TIDDLRVRRVELEsqvdLLQAQSQRLQKHLSSLEAEVQRKQ 1423
Cdd:PRK03918  486 --EKVLKKESELIKLKELAEQLK-------ELEEKLKKyNLEELEKKAEEYE----KLKEKLIKLKGEIKSLKKELEKLE 552

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1424 DVLKEMAAEMNAsphpepglhIEDLRKSLdTNKNQEVSSSLSLSKEEIDLSMESVRQFLSaEGVAVRNAKEFLVRQTRSM 1503
Cdd:PRK03918  553 ELKKKLAELEKK---------LDELEEEL-AELLKELEELGFESVEELEERLKELEPFYN-EYLELKDAEKELEREEKEL 621

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1504 RRRQTALKAAQQHWRHELASAQEVDEDLPGTEV--------------------LGNMRKNLNEETRHLDEMKSAMRKGHD 1563
Cdd:PRK03918  622 KKLEEELDKAFEELAETEKRLEELRKELEELEKkyseeeyeelreeylelsreLAGLRAELEELEKRREEIKKTLEKLKE 701

                         570
                  ....*....|....
gi 568959107 1564 LLKKKEEKLIQLES 1577
Cdd:PRK03918  702 ELEEREKAKKELEK 715

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

1053-1221

1.40e-08

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 60.03 E-value: 1.40e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1053 RAQVQSRTEAFENQIRT------EQQAALQRLREEAETLQKAERASLEQKSRRALEQLREQLEAEERSAQAALR------ 1120
Cdd:COG3206   170 REEARKALEFLEEQLPElrkeleEAEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAalraql 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1121 -----AEKEAEKEAALLQLREQ---LEGERKEAVAGLEKKHS------AELEQLCSSLEAKHQEVISSLQKKIEGAQQkE 1186
Cdd:COG3206   250 gsgpdALPELLQSPVIQQLRAQlaeLEAELAELSARYTPNHPdvialrAQIAALRAQLQQEAQRILASLEAELEALQA-R 328

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 568959107 1187 EAQLQESLgwaeQRAHQKVHQVTEYEQELSSLLRD 1221
Cdd:COG3206   329 EASLQAQL----AQLEARLAELPELEAELRRLERE 359

Myosin_tail_1

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

1075-1458

1.45e-08

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 60.19 E-value: 1.45e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1075 LQRLREEAETLQKAERASLEQ----------------KSRRALEQ----LREQLEAEERSAQAA----LRAEKEAEKEAA 1130
Cdd:pfam01576  648 ALEAKEELERTNKQLRAEMEDlvsskddvgknvheleRSKRALEQqveeMKTQLEELEDELQATedakLRLEVNMQALKA 727

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1131 L----LQLREQLEGERKEAVAGLEKKHSAELEQlcsslEAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQ--K 1204
Cdd:pfam01576  728 QferdLQARDEQGEEKRRQLVKQVRELEAELED-----ERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQlkK 802

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1205 VH-QVTEYEQELSSLlRDKRQEV---EREHERKMDKMKEE--HWQEMADARERYEAEERKQRADLlghltgelerlrrah 1278
Cdd:pfam01576  803 LQaQMKDLQRELEEA-RASRDEIlaqSKESEKKLKNLEAEllQLQEDLAASERARRQAQQERDEL--------------- 866

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1279 ERELESMRQEQDQQLEDLRRRhrdhERKLQDLEVELSSrtkdvkarlAQLNVQEENIRKEKQLLLDAQRQAALEREEATA 1358
Cdd:pfam01576  867 ADEIASGASGKSALQDEKRRL----EARIAQLEEELEE---------EQSNTELLNDRLRKSTLQVEQLTTELAAERSTS 933

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1359 thQHLEEAKkehthlletkQQLRRTIDDLRVRRVELESQVdllqaqSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNASPH 1438
Cdd:pfam01576  934 --QKSESAR----------QQLERQNKELKAKLQEMEGTV------KSKFKSSIAALEAKIAQLEEQLEQESRERQAANK 995

                          410       420
                   ....*....|....*....|....*....
gi 568959107  1439 ---------PEPGLHIEDLRKSLDTNKNQ 1458
Cdd:pfam01576  996 lvrrtekklKEVLLQVEDERRHADQYKDQ 1024

Myosin_tail_1

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

1068-1424

2.04e-08

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 59.42 E-value: 2.04e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1068 RTEQQAALQRLREEAETLQKAERASLEQKSRRALEQLREQLEAEERS------AQAALRAEKE--AEKEAALLQLREQLE 1139
Cdd:pfam01576  325 REQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNkanlekAKQALESENAelQAELRTLQQAKQDSE 404

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1140 GERKEAVAGLEK--------------------KHSAELEQLCSSLEA------KHQEVISSLQKKIEGAQQkeeaQLQEs 1193
Cdd:pfam01576  405 HKRKKLEGQLQElqarlseserqraelaeklsKLQSELESVSSLLNEaegkniKLSKDVSSLESQLQDTQE----LLQE- 479

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1194 lgwaEQRAHQKV-HQVTEYEQELSSLLrdKRQEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRAdllghltgeLE 1272
Cdd:pfam01576  480 ----ETRQKLNLsTRLRQLEDERNSLQ--EQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEA---------LE 544

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1273 RLRRAHERELESMRQ---EQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKA------RLAQLNVQEENIRKEKQLLL 1343
Cdd:pfam01576  545 EGKKRLQRELEALTQqleEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNlekkqkKFDQMLAEEKAISARYAEER 624

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1344 DAQRQAALERE-EATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRR-------VELESQVDLLQAQSQRLQKHLSSL 1415
Cdd:pfam01576  625 DRAEAEAREKEtRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKddvgknvHELERSKRALEQQVEEMKTQLEEL 704


                   ....*....
gi 568959107  1416 EAEVQRKQD 1424
Cdd:pfam01576  705 EDELQATED 713

PRK03918

DNA double-strand break repair ATPase Rad50;

1055-1422

2.13e-08

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 59.31 E-value: 2.13e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1055 QVQSRTEAFENQIRT--EQQAALQRLREEAETLQK--AERASLEQKSRRaLEQLREQLEAEERSAQAALraEKEAEKEAA 1130
Cdd:PRK03918  263 ELEERIEELKKEIEEleEKVKELKELKEKAEEYIKlsEFYEEYLDELRE-IEKRLSRLEEEINGIEERI--KELEEKEER 339

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1131 LLQLREQLEGERKEaVAGLEKKHS---------AELEQLCSSLEAKHQEVISSLQKKIEGAQ---QKEEAQLQESLGWAE 1198
Cdd:PRK03918  340 LEELKKKLKELEKR-LEELEERHElyeeakakkEELERLKKRLTGLTPEKLEKELEELEKAKeeiEEEISKITARIGELK 418

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1199 QRAHQKVHQVTEYE----------QELSSllrDKRQEVEREHERKMDKMKEEhWQEMADARERYEAEERKQRADLLGHlt 1268
Cdd:PRK03918  419 KEIKELKKAIEELKkakgkcpvcgRELTE---EHRKELLEEYTAELKRIEKE-LKEIEEKERKLRKELRELEKVLKKE-- 492

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1269 GELERLRRAHE--RELESMRQEQDqqLEDLRRRHRDHE---RKLQDLEVELSS------RTKDVKARLAQLNVQEENIRK 1337
Cdd:PRK03918  493 SELIKLKELAEqlKELEEKLKKYN--LEELEKKAEEYEklkEKLIKLKGEIKSlkkeleKLEELKKKLAELEKKLDELEE 570

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1338 EKQLLLDAQRQAALER-EEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLE 1416
Cdd:PRK03918  571 ELAELLKELEELGFESvEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELE 650


                  ....*.
gi 568959107 1417 aEVQRK 1422
Cdd:PRK03918  651 -ELEKK 655

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

1070-1596

2.61e-08

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 59.21 E-value: 2.61e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1070 EQQAALQRLREEAETLQKAERASLEQKSRRALEQLREQLEAEERsaqaalraekeaeKEAALLQLREQLEGERKEAVAGL 1149
Cdd:pfam02463  144 IEIIAMMKPERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAE-------------LIIDLEELKLQELKLKEQAKKAL 210

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1150 E------KKHSAELEQLCSSLEAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAH-QKVHQVTEYEQELSSLLRDK 1222
Cdd:pfam02463  211 EyyqlkeKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQvLKENKEEEKEKKLQEEELKL 290

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1223 RQEVEREHERKMDKMKEehwQEMADARERYEAEERKQRADLLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRD 1302
Cdd:pfam02463  291 LAKEEEELKSELLKLER---RKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEK 367

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1303 HERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLLETKQ---- 1378
Cdd:pfam02463  368 LEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQgklt 447

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1379 QLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDvlKEMAAEMNASPHPEPGLHIEDLRKSLDTNKNQ 1458
Cdd:pfam02463  448 EEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQ--KLEERSQKESKARSGLKVLLALIKDGVGGRII 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1459 EVSSSLSLSKEEIDLsmESVRQFLSAEGVAVRNAKEFLVRQT---------RSMRRRQTALKAAQQHWRH--ELASAQEV 1527
Cdd:pfam02463  526 SAHGRLGDLGVAVEN--YKVAISTAVIVEVSATADEVEERQKlvraltelpLGARKLRLLIPKLKLPLKSiaVLEIDPIL 603

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568959107  1528 DEDLPGTEVLGNMRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKLIQLESSLQEEVSDEDTLKGSSIKK 1596
Cdd:pfam02463  604 NLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELT 672

HEC1

COG5185

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...

1170-1449

2.71e-08

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 58.82 E-value: 2.71e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1170 EVISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSsllrdkrqEVEREHERKMDKMKEEHWQEMADAR 1249
Cdd:COG5185   282 ENANNLIKQFENTKEKIAEYTKSIDIKKATESLEEQLAAAEAEQELE--------ESKRETETGIQNLTAEIEQGQESLT 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1250 ERYEAEeRKQRADLLGhltgeLERLRRAhERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLN 1329
Cdd:COG5185   354 ENLEAI-KEEIENIVG-----EVELSKS-SEELDSFKDTIESTKESLDEIPQNQRGYAQEILATLEDTLKAADRQIEELQ 426

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1330 VQ--------EENIRKEKQLLLDAQRQaalEREEATATHQHLEEAKKEHthlletKQQLRRTIDDLRVRRVELESQVDLL 1401
Cdd:COG5185   427 RQieqatssnEEVSKLLNELISELNKV---MREADEESQSRLEEAYDEI------NRSVRSKKEDLNEELTQIESRVSTL 497

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 568959107 1402 QAQsqrLQKHLSSLEAEVQRKQDVLKEMAAEMNASPHPEPGLHIEDLR 1449
Cdd:COG5185   498 KAT---LEKLRAKLERQLEGVRSKLDQVAESLKDFMRARGYAHILALE 542

TPH

pfam13868

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

1220-1433

2.75e-08

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 58.01 E-value: 2.75e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1220 RDKRQEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRADLLGHLTGELERLRRAHERELESMRQEQDQ-------- 1291
Cdd:pfam13868   31 KKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQIEEREQKRQEEYEEKLQEREQmdeiveri 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1292 QLEDLRRRHRDHERKLQDL-EVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEatathQHLEEAKKEH 1370
Cdd:pfam13868  111 QEEDQAEAEEKLEKQRQLReEIDEFNEEQAEWKELEKEEEREEDERILEYLKEKAEREEEREAER-----EEIEEEKERE 185

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568959107  1371 T----HLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEA--EVQRKQDVLKEMAAEM 1433
Cdd:pfam13868  186 IarlrAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQElqQAREEQIELKERRLAE 254

SCP-1

pfam05483

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...

1066-1501

3.08e-08

Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 58.96 E-value: 3.08e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1066 QIRTEQQAALQRLREEAETLQ------KAERASLEQKSRRALEQLrEQLEAEERSAQAALRAEKEAEKEAALLQLREQLE 1139
Cdd:pfam05483  328 QLTEEKEAQMEELNKAKAAHSfvvtefEATTCSLEELLRTEQQRL-EKNEDQLKIITMELQKKSSELEEMTKFKNNKEVE 406

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1140 GERKEAVAGLEKK---HSAELEQLCSSLEAKHQEVISSLQkkiegAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELS 1216
Cdd:pfam05483  407 LEELKKILAEDEKlldEKKQFEKIAEELKGKEQELIFLLQ-----AREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELE 481

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1217 sllRDKRQEVE-REHERKMDKMKEEHWQEMADAreryEAEERKQRADLLGHLTGElERLRRAHER----------ELESM 1285
Cdd:pfam05483  482 ---KEKLKNIElTAHCDKLLLENKELTQEASDM----TLELKKHQEDIINCKKQE-ERMLKQIENleekemnlrdELESV 553

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1286 RQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLE- 1364
Cdd:pfam05483  554 REEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNa 633

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1365 ---EAKKEHTHLLETKQQL-------RRTIDDLRVRRVELESQVDLLQA---QSQRLQKHLSsleaevQRKQDVLKEMAA 1431
Cdd:pfam05483  634 yeiKVNKLELELASAKQKFeeiidnyQKEIEDKKISEEKLLEEVEKAKAiadEAVKLQKEID------KRCQHKIAEMVA 707

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568959107  1432 EMNASPHPEPGLhIEDLRKSLDTNKNQEVSSSLSLSKEEIDLS-----MESVRQFLSAEgvavRNAKEFLVRQTR 1501
Cdd:pfam05483  708 LMEKHKHQYDKI-IEERDSELGLYKNKEQEQSSAKAALEIELSnikaeLLSLKKQLEIE----KEEKEKLKMEAK 777

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

1172-1419

3.67e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 58.77 E-value: 3.67e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1172 ISSLQKKIEGAQQKEEA--QLQEslgwAEQRAHQKVHQVTEYEQELSSLLRDKRQEVEREHERKMDKMKEEHwQEMADAR 1249
Cdd:COG4913   237 LERAHEALEDAREQIELlePIRE----LAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAEL-ARLEAEL 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1250 ERYEAEERKQRADLLghltgELERLRRAHE-RELESMRQEQDQ---QLEDLRRRHRDHERKLQDLEVELSSRTKDVKARL 1325
Cdd:COG4913   312 ERLEARLDALREELD-----ELEAQIRGNGgDRLEQLEREIERlerELEERERRRARLEALLAALGLPLPASAEEFAALR 386

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1326 AQLnvqeenirkeKQLLLDAQRQAALEREEATATHQHLEEAKKEHthlletkQQLRRTIDDLRVRRVELESQVDLLQAqs 1405
Cdd:COG4913   387 AEA----------AALLEALEEELEALEEALAEAEAALRDLRREL-------RELEAEIASLERRKSNIPARLLALRD-- 447

                         250
                  ....*....|....
gi 568959107 1406 qRLQKHLSSLEAEV 1419
Cdd:COG4913   448 -ALAEALGLDEAEL 460

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

1145-1358

3.74e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 57.85 E-value: 3.74e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1145 AVAGLEKKHSAELEQLcssleakhQEVISSLQKKIEgAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSL------ 1218
Cdd:COG4942    17 AQADAAAEAEAELEQL--------QQEIAELEKELA-ALKKEEKALLKQLAALERRIAALARRIRALEQELAALeaelae 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1219 LRDKRQEVEREHERKMDKMKE--------------------EHWQEMADARERYEA--EERKQRADLLGHLTGELERLRR 1276
Cdd:COG4942    88 LEKEIAELRAELEAQKEELAEllralyrlgrqpplalllspEDFLDAVRRLQYLKYlaPARREQAEELRADLAELAALRA 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1277 aherELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEA 1356
Cdd:COG4942   168 ----ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243


                  ..
gi 568959107 1357 TA 1358
Cdd:COG4942   244 PA 245

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

1091-1359

4.27e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 57.47 E-value: 4.27e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1091 ASLEQKSRRALEQLREQLEAEERSAQAALraekeaekeaallqlrEQLEGERKEAVAGLEK--KHSAELEQLCSSLEAKh 1168
Cdd:COG4942    15 AAAQADAAAEAEAELEQLQQEIAELEKEL----------------AALKKEEKALLKQLAAleRRIAALARRIRALEQE- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1169 qevISSLQKKIEGAqQKEEAQLQESLgwAEQRAhqkvhqvtEYEQELSSLLRDKRQeverehERKMDKMKEEHWQEMADA 1248
Cdd:COG4942    78 ---LAALEAELAEL-EKEIAELRAEL--EAQKE--------ELAELLRALYRLGRQ------PPLALLLSPEDFLDAVRR 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1249 RERYEA--EERKQRADLLGHLTGELERLRRAHERE---LESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRtkdvKA 1323
Cdd:COG4942   138 LQYLKYlaPARREQAEELRADLAELAALRAELEAEraeLEALLAELEEERAALEALKAERQKLLARLEKELAEL----AA 213

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 568959107 1324 RLAQLNVQEENIRKekqlLLDAQRQAALEREEATAT 1359
Cdd:COG4942   214 ELAELQQEAEELEA----LIARLEAEAAAAAERTPA 245

COG1340

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];

1162-1436

7.42e-08

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];

Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 56.07 E-value: 7.42e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1162 SSLEAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAhQKVHQVTEYEQELSSL--LRDKRQEVEREHERKmdkmKE 1239
Cdd:COG1340     7 SSSLEELEEKIEELREEIEELKEKRDELNEELKELAEKRD-ELNAQVKELREEAQELreKRDELNEKVKELKEE----RD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1240 EHWQEMADAREryEAEERKQRADLLGHLTGELERLRRAHERElesmrqEQDQQLEDLRRrhrDHERKLQDLEVELSSRTK 1319
Cdd:COG1340    82 ELNEKLNELRE--ELDELRKELAELNKAGGSIDKLRKEIERL------EWRQQTEVLSP---EEEKELVEKIKELEKELE 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1320 DVKArlaqlnvqeenIRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVD 1399
Cdd:COG1340   151 KAKK-----------ALEKNEKLKELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEADELHKEIV 219

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 568959107 1400 LLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNAS 1436
Cdd:COG1340   220 EAQEKADELHEEIIELQKELRELRKELKKLRKKQRAL 256

DUF3584

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

996-1415

7.88e-08

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 57.54 E-value: 7.88e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107   996 QEEQDDSKSSIAEPQSKHTQGSESLlkAQLQKATAEEKEKEEETKIREEESR-RLVCLRAQVQSRTEAFENQIRTEQQAA 1074
Cdd:pfam12128  603 RERLDKAEEALQSAREKQAAAEEQL--VQANGELEKASREETFARTALKNARlDLRRLFDEKQSEKDKKNKALAERKDSA 680

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1075 LQRLREEAetlqkAERASLEQKSRRALEQLREQLEAEERSAQAALRaekeaekeaALLQLREQLEGERKEAVAGLEKKHS 1154
Cdd:pfam12128  681 NERLNSLE-----AQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQ---------VVEGALDAQLALLKAAIAARRSGAK 746

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1155 AELEQL----CSSLEAK--HQEVISSLQKKIEGAQQKEEaqlqeslgwaeqRAHQKVHQVTEYE---QELSSLLRDKRQE 1225
Cdd:pfam12128  747 AELKALetwyKRDLASLgvDPDVIAKLKREIRTLERKIE------------RIAVRRQEVLRYFdwyQETWLQRRPRLAT 814

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1226 VEREHERKMDKMKEEHWQEMADARERYEAEER------KQRADLLGHLTG---ELERLRRAHE----RELESMRQEQDQQ 1292
Cdd:pfam12128  815 QLSNIERAISELQQQLARLIADTKLRRAKLEMerkaseKQQVRLSENLRGlrcEMSKLATLKEdansEQAQGSIGERLAQ 894

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1293 LEDLRRRHR----DHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREE-ATATHQHLEEAK 1367
Cdd:pfam12128  895 LEDLKLKRDylseSVKKYVEHFKNVIADHSGSGLAETWESLREEDHYQNDKGIRLLDYRKLVPYLEQwFDVRVPQSIMVL 974

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*....
gi 568959107  1368 KEHTHLL-ETKQQLRRTIDDLRvRRVelesqvdllQAQSQRLQKHLSSL 1415
Cdd:pfam12128  975 REQVSILgVDLTEFYDVLADFD-RRI---------ASFSRELQREVGEE 1013

Cast

pfam10174

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...

1141-1573

9.75e-08

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.

Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 57.14 E-value: 9.75e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1141 ERKEAVAGLE--KKHS----AELEQLCSSLEAKHQEVISsLQKKIE--GAQQKEEAQ----LQESLGWAEQRA---HQKV 1205
Cdd:pfam10174  269 DREEEIKQMEvyKSHSkfmkNKIDQLKQELSKKESELLA-LQTKLEtlTNQNSDCKQhievLKESLTAKEQRAailQTEV 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1206 HQVTEYEQELSSLLRDKRQEVEREHERKMDKMKE-EHWQEMADARERYEAEERKQRADLLGHLT---GELERLRRAHER- 1280
Cdd:pfam10174  348 DALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEiRDLKDMLDVKERKINVLQKKIENLQEQLRdkdKQLAGLKERVKSl 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1281 ------------ELESMRQEQDQQLEDLRRRHRDHERKLQDlevELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQ 1348
Cdd:pfam10174  428 qtdssntdtaltTLEEALSEKERIIERLKEQREREDRERLE---ELESLKKENKDLKEKVSALQPELTEKESSLIDLKEH 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1349 AALEREEATATHQHLE------EAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRK 1422
Cdd:pfam10174  505 ASSLASSGLKKDSKLKsleiavEQKKEECSKLENQLKKAHNAEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERL 584

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1423 QDVLKEMAAEMNASPHPEPGLHIEDLRKSLDTNKnqevssslslskeeidlsmeSVRQFLSAEGVAVRNAKEFLVRQtrs 1502
Cdd:pfam10174  585 LGILREVENEKNDKDKKIAELESLTLRQMKEQNK--------------------KVANIKHGQQEMKKKGAQLLEEA--- 641

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568959107  1503 mRRRQTALKAAQQHWRHE--LASAQEVDEDLPGTEV-LGNMRKNLNEETRHLDEMKSAMRKG-HDLLKKKEEKLI 1573
Cdd:pfam10174  642 -RRREDNLADNSQQLQLEelMGALEKTRQELDATKArLSSTQQSLAEKDGHLTNLRAERRKQlEEILEMKQEALL 715

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

1345-1593

1.00e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 56.31 E-value: 1.00e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1345 AQRQAALE--REEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRK 1422
Cdd:COG4942    23 AEAEAELEqlQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1423 QDVLKEMAAE---MNASPHPEPGLHIEDlrkSLDTNKNQEVssslslskeeidlsMESVRQFLSAEGVAVRNAKEFLVRQ 1499
Cdd:COG4942   103 KEELAELLRAlyrLGRQPPLALLLSPED---FLDAVRRLQY--------------LKYLAPARREQAEELRADLAELAAL 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1500 TRS---MRRRQTALKAAQQHWRHELASAQEVDEDLpgtevLGNMRKNLNEETRHLDEmksamrkghdlLKKKEEKLIQLE 1576
Cdd:COG4942   166 RAEleaERAELEALLAELEEERAALEALKAERQKL-----LARLEKELAELAAELAE-----------LQQEAEELEALI 229

                         250
                  ....*....|....*..
gi 568959107 1577 SSLQEEVSDEDTLKGSS 1593
Cdd:COG4942   230 ARLEAEAAAAAERTPAA 246

Myosin_tail_1

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

1022-1429

2.53e-07

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 55.95 E-value: 2.53e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1022 KAQLQKATAEEKEKEEETK--IREEESRRLVCLRAQVQSRTEAFENQIRTEQQAA--LQRLREEAETL--QKAERASLEQ 1095
Cdd:pfam01576  121 KLQLEKVTTEAKIKKLEEDilLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAksLSKLKNKHEAMisDLEERLKKEE 200

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1096 KSRRALEQLREQLEAEERSAQAALraekeAEKEAALLQLREQL---EGERKEAVAGLEKKHSAELEQLCSSLEAKHQevI 1172
Cdd:pfam01576  201 KGRQELEKAKRKLEGESTDLQEQI-----AELQAQIAELRAQLakkEEELQAALARLEEETAQKNNALKKIRELEAQ--I 273

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1173 SSLQKKIE---GAQQKEEAQ--------------LQESLGwaEQRAHQKVHqvTEYEQELSSLLRDKRQEVeREHERKMD 1235
Cdd:pfam01576  274 SELQEDLEserAARNKAEKQrrdlgeelealkteLEDTLD--TTAAQQELR--SKREQEVTELKKALEEET-RSHEAQLQ 348

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1236 KMKEEHWQEMADARERYEAEER------KQRADLLG---HLTGELERLRRAhERELESMRQEQDQQLEDLRRRHRDHER- 1305
Cdd:pfam01576  349 EMRQKHTQALEELTEQLEQAKRnkanleKAKQALESenaELQAELRTLQQA-KQDSEHKRKKLEGQLQELQARLSESERq 427

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1306 ------KLQDLEVELSSRT--------------KDVKARLAQLN-----VQEENIRK-----------------EKQLLL 1343
Cdd:pfam01576  428 raelaeKLSKLQSELESVSsllneaegkniklsKDVSSLESQLQdtqelLQEETRQKlnlstrlrqledernslQEQLEE 507

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1344 DAQRQAALEREEATATHQHLEEAKKEHTHLL------ETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEA 1417
Cdd:pfam01576  508 EEEAKRNVERQLSTLQAQLSDMKKKLEEDAGtlealeEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLV 587

                          490
                   ....*....|..
gi 568959107  1418 EVQRKQDVLKEM 1429
Cdd:pfam01576  588 DLDHQRQLVSNL 599

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

1174-1592

3.02e-07

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 55.75 E-value: 3.02e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1174 SLQKKIEGAQQ---KEEAQLQESLGWAEQR-----AHQKVHQVTEYEQELSSLLRdkrqEVEREHERKMdkmkeehwqEM 1245
Cdd:pfam02463  139 VQGGKIEIIAMmkpERRLEIEEEAAGSRLKrkkkeALKKLIEETENLAELIIDLE----ELKLQELKLK---------EQ 205

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1246 ADARERYEAEERKQRAdllghltgELERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEvelssrtkdvkarl 1325
Cdd:pfam02463  206 AKKALEYYQLKEKLEL--------EEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKE-------------- 263

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1326 aqlnvQEENIRKEKQLLLDAQRQAALEREEAtathqhleeakkehtHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQS 1405
Cdd:pfam02463  264 -----EEKLAQVLKENKEEEKEKKLQEEELK---------------LLAKEEEELKSELLKLERRKVDDEEKLKESEKEK 323

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1406 QRLQKHLSSLEAEVQRKQDVLKEMAAemnasPHPEPGLHIEDLRKSLDTNKNQEvssslslskEEIDLSMESVRQFLSAE 1485
Cdd:pfam02463  324 KKAEKELKKEKEEIEELEKELKELEI-----KREAEEEEEEELEKLQEKLEQLE---------EELLAKKKLESERLSSA 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1486 GVAVRNAKEFLVRQTRSmrrRQTALKAAQQHWRHELASAQEVDEDLPGTEVLGNMRKNLNEETRHLDEMKSAMRKGHDLL 1565
Cdd:pfam02463  390 AKLKEEELELKSEEEKE---AQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELE 466

                          410       420
                   ....*....|....*....|....*..
gi 568959107  1566 KKKEEKLIQLESSLQEEVSDEDTLKGS 1592
Cdd:pfam02463  467 LKKSEDLLKETQLVKLQEQLELLLSRQ 493

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

1095-1361

3.62e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 55.31 E-value: 3.62e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1095 QKSRRALEQLREQLEAEERSAQAAlraekeAEKEAALLQLREQLEgERKEAVAGLEKKHSAELEQlcssleAKHQEVISS 1174
Cdd:COG4913   606 FDNRAKLAALEAELAELEEELAEA------EERLEALEAELDALQ-ERREALQRLAEYSWDEIDV------ASAEREIAE 672

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1175 LQKKIEGAQQ--KEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSlLRDKRQEVEREHERKMDkmKEEHWQEMADARERY 1252
Cdd:COG4913   673 LEAELERLDAssDDLAALEEQLEELEAELEELEEELDELKGEIGR-LEKELEQAEEELDELQD--RLEAAEDLARLELRA 749

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1253 EAEERKQRADLLGHltgeLERLRRAHERELESMRQEQDQQLEDLRRRHRDHERK----LQDLEVELSSRTkDVKARLAQL 1328
Cdd:COG4913   750 LLEERFAAALGDAV----ERELRENLEERIDALRARLNRAEEELERAMRAFNREwpaeTADLDADLESLP-EYLALLDRL 824

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 568959107 1329 nVQEENIRKE---KQLLLDAQRQ------AALEREEATATHQ 1361
Cdd:COG4913   825 -EEDGLPEYEerfKELLNENSIEfvadllSKLRRAIREIKER 865

Caldesmon

pfam02029

Caldesmon;

1089-1397

3.85e-07

Caldesmon;

Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 54.87 E-value: 3.85e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1089 ERASLEQKSRRALEQLREQLEAEERSAQAalraekeaekeAALLQLREQ-LEGERKEAVAglEKKHSAELEQLCSSLEAK 1167
Cdd:pfam02029    4 EEEAARERRRRAREERRRQKEEEEPSGQV-----------TESVEPNEHnSYEEDSELKP--SGQGGLDEEEAFLDRTAK 70

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1168 HQE-VISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLLRDKRQEVErEHERKMDKMKEEHW-QEM 1245
Cdd:pfam02029   71 REErRQKRLQEALERQKEFDPTIADEKESVAERKENNEEEENSSWEKEEKRDSRLGRYKEE-ETEIREKEYQENKWsTEV 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1246 ADARERYEAEERKQradllghlTGELERLRRAHERE---LESMRQEQDQQLED---LRRRHRDHERKLQDLEVELSSRTK 1319
Cdd:pfam02029  150 RQAEEEGEEEEDKS--------EEAEEVPTENFAKEevkDEKIKKEKKVKYESkvfLDQKRGHPEVKSQNGEEEVTKLKV 221

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1320 DVKARLAQLNV-----QEENIRKEKQLLLDAQRQ--AALEREEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRV 1392
Cdd:pfam02029  222 TTKRRQGGLSQsqereEEAEVFLEAEQKLEELRRrrQEKESEEFEKLRQKQQEAELELEELKKKREERRKLLEEEEQRRK 301


                   ....*
gi 568959107  1393 ELESQ 1397
Cdd:pfam02029  302 QEEAE 306

PspA_IM30

pfam04012

PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent ...

1272-1436

4.35e-07

PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent transcription. The PspA protein, a negative regulator of the Escherichia coli phage shock psp operon, is produced when virulence factors are exported through secretins in many Gram-negative pathogenic bacteria and its homolog in plants, VIPP1, plays a critical role in thylakoid biogenesis, essential for photosynthesis. Activation of transcription by the enhancer-dependent bacterial sigma(54) containing RNA polymerase occurs through ATP hydrolysis-driven protein conformational changes enabled by activator proteins that belong to the large AAA(+) mechanochemical protein family. It has been shown that PspA directly and specifically acts upon and binds to the AAA(+) domain of the PspF transcription activator.

Pssm-ID: 461130 [Multi-domain] Cd Length: 215 Bit Score: 52.76 E-value: 4.35e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1272 ERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKdvKARLAqLNVQEENIRKEKqllldAQRQAAL 1351
Cdd:pfam04012   24 EKMLEQAIRDMQSELVKARQALAQTIARQKQLERRLEQQTEQAKKLEE--KAQAA-LTKGNEELAREA-----LAEKKSL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1352 EreeatathQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQA--QSQRLQKHL---------SSLEAEVQ 1420
Cdd:pfam04012   96 E--------KQAEALETQLAQQRSAVEQLRKQLAALETKIQQLKAKKNLLKArlKAAKAQEAVqtslgslstSSATDSFE 167

                          170
                   ....*....|....*.
gi 568959107  1421 RKQDVLKEMAAEMNAS 1436
Cdd:pfam04012  168 RIEEKIEEREARADAA 183

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

1243-1431

4.36e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 55.02 E-value: 4.36e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1243 QEMADARERYEAEERKQRAD-LLGHLTGELERLR---RAHERELESMRQEQDqqLEDLRRRHRDHERKLQDLEVELS--- 1315
Cdd:COG3206   155 NALAEAYLEQNLELRREEARkALEFLEEQLPELRkelEEAEAALEEFRQKNG--LVDLSEEAKLLLQQLSELESQLAear 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1316 SRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEEAKK---EHTHLLETKQQLRRTIDDLRVR-- 1390
Cdd:COG3206   233 AELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARytpNHPDVIALRAQIAALRAQLQQEaq 312

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 568959107 1391 --RVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAA 1431
Cdd:COG3206   313 riLASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRR 355

CHASE3

COG5278

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];

1065-1502

4.55e-07

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];

Pssm-ID: 444089 [Multi-domain] Cd Length: 530 Bit Score: 54.91 E-value: 4.55e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1065 NQIRTEQQAALQRLRE--EAETLQKAERASLEQKSRRALEQLREQLEA-EERSAQAALRAEKEAEKEAALLQLREQLEGE 1141
Cdd:COG5278    82 EEARAEIDELLAELRSltADNPEQQARLDELEALIDQWLAELEQVIALrRAGGLEAALALVRSGEGKALMDEIRARLLLL 161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1142 RKEAVAGLEKKHSAELEQLCSSLEAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLLRD 1221
Cdd:COG5278   162 ALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAALALA 241

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1222 KRQEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRADLLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHR 1301
Cdd:COG5278   242 LALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAAAAA 321

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1302 DHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLLETKQQLR 1381
Cdd:COG5278   322 AAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAAAAA 401

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1382 RTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNASPHPEPGLHIEDLRKSLDTNKNQEVS 1461
Cdd:COG5278   402 AAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAALAAAA 481

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|.
gi 568959107 1462 SSLSLSKEEIDLSMESVRQFLSAEGVAVRNAKEFLVRQTRS 1502
Cdd:COG5278   482 AALAEAEAAAALAAAAALSLALALAALLLAAAEAALAAALA 522

HCR

pfam07111

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...

1066-1585

8.73e-07

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.

Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 53.99 E-value: 8.73e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1066 QIRTEQQAALQRLREEAETLQKAeraSLEQKSRRALEQLR-EQLEAEERSAQAALRAEKEAEKEAALLqlREQLE-GERK 1143
Cdd:pfam07111   66 ELISRQLQELRRLEEEVRLLRET---SLQQKMRLEAQAMElDALAVAEKAGQAEAEGLRAALAGAEMV--RKNLEeGSQR 140

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1144 EavagLEKKHSAELEQLcSSLEAKHQEVISSLQKKIEGaqqkeeaqLQESLGWAEQRAHQKVHQVTEYEQElSSLLRDKR 1223
Cdd:pfam07111  141 E----LEEIQRLHQEQL-SSLTQAHEEALSSLTSKAEG--------LEKSLNSLETKRAGEAKQLAEAQKE-AELLRKQL 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1224 QEVEREHERK---MDKMKEEHWQEMADARERYEAE-ERKQRADLLGHL---------TGELERLR--------RAHEREL 1282
Cdd:pfam07111  207 SKTQEELEAQvtlVESLRKYVGEQVPPEVHSQTWElERQELLDTMQHLqedradlqaTVELLQVRvqslthmlALQEEEL 286

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1283 -------ESMRQEQDQQLEDLRRRHRDH------ERKLQDLevELSSRTKDVKARLAQLNVQEENIRKE----KQLLLDA 1345
Cdd:pfam07111  287 trkiqpsDSLEPEFPKKCRSLLNRWREKvfalmvQLKAQDL--EHRDSVKQLRGQVAELQEQVTSQSQEqailQRALQDK 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1346 QRQAALEREEATATHQHLEEA----KKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQR 1421
Cdd:pfam07111  365 AAEVEVERMSAKGLQMELSRAqearRRQQQQTASAEEQLKFVVNAMSSTQIWLETTMTRVEQAVARIPSLSNRLSYAVRK 444

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1422 KQDVLKEMAAEM-------NASPHPEPGLHIE-DLRKSLdtnknQEVSSSLSLSKEEIDLSMESVRQflsaegvAVRNAK 1493
Cdd:pfam07111  445 VHTIKGLMARKValaqlrqESCPPPPPAPPVDaDLSLEL-----EQLREERNRLDAELQLSAHLIQQ-------EVGRAR 512

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1494 EflvrQTRSMRRRqtaLKAAQQHWRHELASAQEVDEDLpgTEVLGNMRKNLNEETRHLDEMKSAMRKGHDLLKKK-EEKL 1572
Cdd:pfam07111  513 E----QGEAERQQ---LSEVAQQLEQELQRAQESLASV--GQQLEVARQGQQESTEEAASLRQELTQQQEIYGQAlQEKV 583

                          570
                   ....*....|...
gi 568959107  1573 IQLESSLQEEVSD 1585
Cdd:pfam07111  584 AEVETRLREQLSD 596

CwlO1

COG3883

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...

1246-1436

9.22e-07

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];

Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 53.30 E-value: 9.22e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1246 ADARERYEAEERKQRADLLGHLTGELERLrrahERELESMRQEQDQ---QLEDLRRRHRDHERKLQDLEVELSSRTKDVK 1322
Cdd:COG3883    14 ADPQIQAKQKELSELQAELEAAQAELDAL----QAELEELNEEYNElqaELEALQAEIDKLQAEIAEAEAEIEERREELG 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1323 ARLAQLNVQEENIRKEKQLLLDAQRQAALEREEA-----TATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQ 1397
Cdd:COG3883    90 ERARALYRSGGSVSYLDVLLGSESFSDFLDRLSAlskiaDADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAA 169

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 568959107 1398 VDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNAS 1436
Cdd:COG3883   170 KAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAA 208

PRK01156

chromosome segregation protein; Provisional

1081-1430

1.10e-06

chromosome segregation protein; Provisional

Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 53.75 E-value: 1.10e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1081 EAETLQKAERASLEQKSRRA-LEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQLEGERKEAVAGLEKKHSAELEQ 1159
Cdd:PRK01156  330 KLSVLQKDYNDYIKKKSRYDdLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKK 409

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1160 LCSSLEAKHQEV---ISSLQKKIEGAQQKEEaQLQESLGWAEQR----------AHQKVHQVTEYEQELSSLLRDKRQEV 1226
Cdd:PRK01156  410 ELNEINVKLQDIsskVSSLNQRIRALRENLD-ELSRNMEMLNGQsvcpvcgttlGEEKSNHIINHYNEKKSRLEEKIREI 488

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1227 ERE----HERKMDKMKEEHWQEMADAReRYEAEERK---QRADLlGHLTGELERLRRAHERELESMRQEQDQQLEDLRRR 1299
Cdd:PRK01156  489 EIEvkdiDEKIVDLKKRKEYLESEEIN-KSINEYNKiesARADL-EDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSK 566

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1300 HRDH-----ERKLQDLEV------ELSSRTKDVKARLAQLNVQ--------EENIRK----------------EKQLLLD 1344
Cdd:PRK01156  567 RTSWlnalaVISLIDIETnrsrsnEIKKQLNDLESRLQEIEIGfpddksyiDKSIREieneannlnnkyneiqENKILIE 646

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1345 AQRQAALEREEATATHQHLEEAKKEHT-HLLETK---QQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQ 1420
Cdd:PRK01156  647 KLRGKIDNYKKQIAEIDSIIPDLKEITsRINDIEdnlKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLE 726

                         410
                  ....*....|
gi 568959107 1421 RKQDVLKEMA 1430
Cdd:PRK01156  727 SMKKIKKAIG 736

PRK03918

DNA double-strand break repair ATPase Rad50;

1065-1358

2.04e-06

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 52.76 E-value: 2.04e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1065 NQIRTEQQAALQRLREEAETLQKAERASLEQKSRRALEQLREQL-EAEERSAQAALraekeaekeaallqlrEQLEGERK 1143
Cdd:PRK03918  462 KRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLkELEEKLKKYNL----------------EELEKKAE 525

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1144 EAVAGLEK--KHSAELEQLCSSLEaKHQEVISSLqKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSL--- 1218
Cdd:PRK03918  526 EYEKLKEKliKLKGEIKSLKKELE-KLEELKKKL-AELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFyne 603

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1219 ---LRDKRQEVEREhERKMDKMKEEHWQEMAD-ARERYEAEERKQRADLLGHLTGElERLRRAHER--ELESMRQEQDQQ 1292
Cdd:PRK03918  604 yleLKDAEKELERE-EKELKKLEEELDKAFEElAETEKRLEELRKELEELEKKYSE-EEYEELREEylELSRELAGLRAE 681

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568959107 1293 LEDLRRRHRDHERKLQDLEVELSSRTK------DVKARLAQLNVQEENIRKEKQLLldaqRQAALEREEATA 1358
Cdd:PRK03918  682 LEELEKRREEIKKTLEKLKEELEEREKakkeleKLEKALERVEELREKVKKYKALL----KERALSKVGEIA 749

rad50

TIGR00606

rad50; All proteins in this family for which functions are known are involvedin recombination, ...

996-1581

2.11e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).

Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 53.13 E-value: 2.11e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107   996 QEEQDDSKSSIAEPQSKHTQGSESLLKaqlqkataeEKEKEEETKIREEESRRLVCLRAQVQSRTEAFE-NQIRTEQQAA 1074
Cdd:TIGR00606  278 KKQMEKDNSELELKMEKVFQGTDEQLN---------DLYHNHQRTVREKERELVDCQRELEKLNKERRLlNQEKTELLVE 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1075 LQRLREEAETLQKAERAsleQKSRRALEQLREQLEAEERSAQAALRAEKEAEKeaallqLREQLEGERKEA---VAGLEK 1151
Cdd:TIGR00606  349 QGRLQLQADRHQEHIRA---RDSLIQSLATRLELDGFERGPFSERQIKNFHTL------VIERQEDEAKTAaqlCADLQS 419

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1152 KHSAELEQLcSSLEAKHQEVISSLQKKIEGAQQKEE------AQLQESLGwAEQRAHQKVHQVTEYEQELS-----SLLR 1220
Cdd:TIGR00606  420 KERLKQEQA-DEIRDEKKGLGRTIELKKEILEKKQEelkfviKELQQLEG-SSDRILELDQELRKAERELSkaeknSLTE 497

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1221 DKRQEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRADLLGHLTGELERLRRAHER----------------ELES 1284
Cdd:TIGR00606  498 TLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRhsdeltsllgyfpnkkQLED 577

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1285 MRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENI-------------RKEKQLLLDAQRQAAL 1351
Cdd:TIGR00606  578 WLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLfdvcgsqdeesdlERLKEEIEKSSKQRAM 657

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1352 EREEATATHQHLEEAKKEHTHLLETKQQLRRTiddlrvrRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEM-- 1429
Cdd:TIGR00606  658 LAGATAVYSQFITQLTDENQSCCPVCQRVFQT-------EAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMlg 730

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1430 AAEMNASPHPEPGLHIEDLRksldtNKNQEVSSSLSLSKEEIDLSMESVRQFLSAEGVAvrnakEFLVRQTRSMRRRQTA 1509
Cdd:TIGR00606  731 LAPGRQSIIDLKEKEIPELR-----NKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESA-----KVCLTDVTIMERFQME 800

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568959107  1510 LKAAQQHWRHELASAQEVDEDLPGTEVlgnmRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKLIQLESSLQE 1581
Cdd:TIGR00606  801 LKDVERKIAQQAAKLQGSDLDRTVQQV----NQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNE 868

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

1198-1425

2.12e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 52.71 E-value: 2.12e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1198 EQRAHQKVHQVTEYEQELSSLLRDKRQEVErEHERKMDKMKEEHW----QEMADARERYEAEERKQRADLLGHLTgELER 1273
Cdd:COG3206   163 EQNLELRREEARKALEFLEEQLPELRKELE-EAEAALEEFRQKNGlvdlSEEAKLLLQQLSELESQLAEARAELA-EAEA 240

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1274 LRRAHERELESMRQE-----QDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLL---DA 1345
Cdd:COG3206   241 RLAALRAQLGSGPDAlpellQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILaslEA 320

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1346 QRQAALEREEATAthQHLEEAKKEHTHLLETKQQLRRtiddlrvrrveLESQVDLLQAQSQRLQKHLSslEAEVQRKQDV 1425
Cdd:COG3206   321 ELEALQAREASLQ--AQLAQLEARLAELPELEAELRR-----------LEREVEVARELYESLLQRLE--EARLAEALTV 385

PTZ00121

MAEBL; Provisional

865-1362

2.36e-06

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.84 E-value: 2.36e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  865 QKENENSDPKASSSQMAPELDPGGDQPSRASKKQQAEDPVQAGKEGECRRESAAKEPKEASALENTSDVSEESEIHghlk 944
Cdd:PTZ00121 1489 KKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKK---- 1564

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  945 darhsgseasgpksflgldlgfrsrisehlldgdtlspvlggghwEAQGLDQEEQDDSKSsiaepqskhtqgsesllkaq 1024
Cdd:PTZ00121 1565 ---------------------------------------------KAEEAKKAEEDKNMA-------------------- 1579

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1025 lqkataeekekeeetkireeeSRRLVCLRAQVQSRTEAFENQIRTEQQAALQRLREEAETLQKAERASLEQKSRRALEQL 1104
Cdd:PTZ00121 1580 ---------------------LRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQL 1638

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1105 REQLEAEERSAQaalraekeaekeaallQLREQlegERKEAVAGLEKKHSAELEQlcssleAKHQEvissLQKKIEGAQQ 1184
Cdd:PTZ00121 1639 KKKEAEEKKKAE----------------ELKKA---EEENKIKAAEEAKKAEEDK------KKAEE----AKKAEEDEKK 1689

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1185 KEEAQLQEslgwAEQRahQKVHQVTEYEQElsslLRDKRQEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRADLL 1264
Cdd:PTZ00121 1690 AAEALKKE----AEEA--KKAEELKKKEAE----EKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKI 1759

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1265 GHLTGELERLRRAHERELESMRQEQDQQlEDLRRRhrdherklqdleVELSSRTKDVKARLAqlNVQEEN------IRKE 1338
Cdd:PTZ00121 1760 AHLKKEEEKKAEEIRKEKEAVIEEELDE-EDEKRR------------MEVDKKIKDIFDNFA--NIIEGGkegnlvINDS 1824

                         490       500
                  ....*....|....*....|....*...
gi 568959107 1339 KQLLLDAQRQAA----LEREEATATHQH 1362
Cdd:PTZ00121 1825 KEMEDSAIKEVAdsknMQLEEADAFEKH 1852

Mplasa_alph_rch

TIGR04523

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...

1064-1586

2.39e-06

Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 52.72 E-value: 2.39e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1064 ENQIRTEQQAaLQRLREEAETLQKaERASLEQKSRRALEQLRE-QLEAEERSAQaalraekEAEKEAALLQLREQLEGER 1142
Cdd:TIGR04523  231 KDNIEKKQQE-INEKTTEISNTQT-QLNQLKDEQNKIKKQLSEkQKELEQNNKK-------IKELEKQLNQLKSEISDLN 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1143 KEAVAGLEKKHSAELEQLCSSLE------AKHQEVISSLQKKIEGAQQK------EEAQLQESLGWAEQRAHQKVHQVTE 1210
Cdd:TIGR04523  302 NQKEQDWNKELKSELKNQEKKLEeiqnqiSQNNKIISQLNEQISQLKKEltnsesENSEKQRELEEKQNEIEKLKKENQS 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1211 YEQELSSL------LRDKRQEVEREHERKMDKMK--EEHWQEMADARERYEAEERKQrADLLGHLTGELERLRRAHErEL 1282
Cdd:TIGR04523  382 YKQEIKNLesqindLESKIQNQEKLNQQKDEQIKklQQEKELLEKEIERLKETIIKN-NSEIKDLTNQDSVKELIIK-NL 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1283 ESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKarlaQLNVQEENIRKEKQLLldAQRQAALEREEatathQH 1362
Cdd:TIGR04523  460 DNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELK----KLNEEKKELEEKVKDL--TKKISSLKEKI-----EK 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1363 LEEAKKEhthlLETK-QQLRRTI--DDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEmnasphp 1439
Cdd:TIGR04523  529 LESEKKE----KESKiSDLEDELnkDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKE------- 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1440 epglhIEDLRKSLDTNknqevSSSLSLSKEEIDLSMESVRQfLSAEGVAVRNAKEFLVRQTRSMrrrQTALKAAQQHWRH 1519
Cdd:TIGR04523  598 -----KKDLIKEIEEK-----EKKISSLEKELEKAKKENEK-LSSIIKNIKSKKNKLKQEVKQI---KETIKEIRNKWPE 663

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568959107  1520 ELASAQEVDEDLpgTEVLGNMRKNLNEETRHLDEMKSAMRKGHDLLKKKEE-KLIQLESSLQEEVSDE 1586
Cdd:TIGR04523  664 IIKKIKESKTKI--DDIIELMKDWLKELSLHYKKYITRMIRIKDLPKLEEKyKEIEKELKKLDEFSKE 729

mukB

chromosome partition protein MukB;

1065-1353

2.82e-06

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 52.65 E-value: 2.82e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1065 NQIRTEQQAALQRLREEaetlqkaeraslEQKSRRALEQLREQLEAEERSA-QAALraEKEAEKEAALLQLREQLEgERK 1143
Cdd:PRK04863  843 NRRRVELERALADHESQ------------EQQQRSQLEQAKEGLSALNRLLpRLNL--LADETLADRVEEIREQLD-EAE 907

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1144 EAVAGLEK--KHSAELEQLCSSLEAKHQEvISSLQKKIEGAQQKEEAQLQESLGWAE---QRAH---QKVHQVTEYEQEL 1215
Cdd:PRK04863  908 EAKRFVQQhgNALAQLEPIVSVLQSDPEQ-FEQLKQDYQQAQQTQRDAKQQAFALTEvvqRRAHfsyEDAAEMLAKNSDL 986

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1216 SSLLRDKRQEVEREHERKMDKMKE------EHWQEMADARERYEA-----EERKQRADLLG-HLTGELERLRRAHERELe 1283
Cdd:PRK04863  987 NEKLRQRLEQAEQERTRAREQLRQaqaqlaQYNQVLASLKSSYDAkrqmlQELKQELQDLGvPADSGAEERARARRDEL- 1065

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568959107 1284 smrqeqDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKA---RLAQLNVQEENIRKEKQLLLDAQRQAALER 1353
Cdd:PRK04863 1066 ------HARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKlerDYHEMREQVVNAKAGWCAVLRLVKDNGVER 1132

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

1096-1431

2.92e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 52.65 E-value: 2.92e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1096 KSRRALEQLREQLEAEERSAQAALRaekeaekeaaLLQLREQLEgERKEAVAGLEKKHSAELEQLCSSLEA-KHQEVISS 1174
Cdd:COG3096   283 LSERALELRRELFGARRQLAEEQYR----------LVEMARELE-ELSARESDLEQDYQAASDHLNLVQTAlRQQEKIER 351

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1175 LQKKIEGAQQKEEAQLQESLGWAEQRAHQKVhQVTEYEQELSSL---LRDKRQEVEREHERKMdkmkeeHWQEMADARER 1251
Cdd:COG3096   352 YQEDLEELTERLEEQEEVVEEAAEQLAEAEA-RLEAAEEEVDSLksqLADYQQALDVQQTRAI------QYQQAVQALEK 424

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1252 yeAEERKQRADLLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEV---ELSSRTKDVKARlaql 1328
Cdd:COG3096   425 --ARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKiagEVERSQAWQTAR---- 498

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1329 nvqeENIRKEKQLLLDAQRQAALEREEATAtHQHLEEAKKEHTHLLETKQQLRRTI---DDLRVRRVELESQVDLLQAQS 1405
Cdd:COG3096   499 ----ELLRRYRSQQALAQRLQQLRAQLAEL-EQRLRQQQNAERLLEEFCQRIGQQLdaaEELEELLAELEAQLEELEEQA 573

                         330       340
                  ....*....|....*....|....*.
gi 568959107 1406 QRLQKHLSSLEAEVQRKQDVLKEMAA 1431
Cdd:COG3096   574 AEAVEQRSELRQQLEQLRARIKELAA 599

Mitofilin

pfam09731

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ...

1054-1403

3.70e-06

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.

Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 52.07 E-value: 3.70e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1054 AQVQSRTEAFENQIRTEQQAALQRLREEAETLQKA---ERASLEQKSRRALEQLREQLEAEERSAQAALRAEKEAEKE-- 1128
Cdd:pfam09731  142 ESATAVAKEAKDDAIQAVKAHTDSLKEASDTAEISrekATDSALQKAEALAEKLKEVINLAKQSEEEAAPPLLDAAPEtp 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1129 ----AALLQLREQLEGERKEA--VAGLEKKHSAELEQLCSSLEAKHQEVISSLqKKIEGAQQKEEAQLQESLGWAEQRAH 1202
Cdd:pfam09731  222 pklpEHLDNVEEKVEKAQSLAklVDQYKELVASERIVFQQELVSIFPDIIPVL-KEDNLLSNDDLNSLIAHAHREIDQLS 300

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1203 QK-VHQVTEYEQELSSLLRDKRQEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRADLLGHLTGELERLRRAHERE 1281
Cdd:pfam09731  301 KKlAELKKREEKHIERALEKQKEELDKLAEELSARLEEVRAADEAQLRLEFEREREEIRESYEEKLRTELERQAEAHEEH 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1282 LESMRQEQDQQLEdlrRRHrdherklqdlevelssrTKDVKARLAqlnvQEENIRKEKqllLDAQRQAALEREEATATHQ 1361
Cdd:pfam09731  381 LKDVLVEQEIELQ---REF-----------------LQDIKEKVE----EERAGRLLK---LNELLANLKGLEKATSSHS 433

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 568959107  1362 HLEEAKKEHTHLLETKQQLRRTIDD--LRVRRVELESQVDLLQA 1403
Cdd:pfam09731  434 EVEDENRKAQQLWLAVEALRSTLEDgsADSRPRPLVRELKALKE 477

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

1199-1435

3.96e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 52.26 E-value: 3.96e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1199 QRAHQKVHQ-VTEY---------EQELSsLLRDKRQEVEREHERkmdkmkeehwQEMADARERYEAEERKQRADLLGHLT 1268
Cdd:COG3096   812 QRLHQAFSQfVGGHlavafapdpEAELA-ALRQRRSELERELAQ----------HRAQEQQLRQQLDQLKEQLQLLNKLL 880

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1269 GELERLRRA-HERELESMRQEQDQQLEDLR--RRHRDHERKLQDLEVELSSRTKD---VKARLAQLNVQEENIRKEKQLL 1342
Cdd:COG3096   881 PQANLLADEtLADRLEELREELDAAQEAQAfiQQHGKALAQLEPLVAVLQSDPEQfeqLQADYLQAKEQQRRLKQQIFAL 960

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1343 LD-AQRQAALEREEATathQHLEEAKKEHTHLletKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAevqr 1421
Cdd:COG3096   961 SEvVQRRPHFSYEDAV---GLLGENSDLNEKL---RARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKSSRDA---- 1030

                         250
                  ....*....|....
gi 568959107 1422 KQDVLKEMAAEMNA 1435
Cdd:COG3096  1031 KQQTLQELEQELEE 1044

Golgin_A5

pfam09787

Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ...

1163-1341

4.09e-06

Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.

Pssm-ID: 462900 [Multi-domain] Cd Length: 305 Bit Score: 50.91 E-value: 4.09e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1163 SLEAKHQEVISSLQKKIEGAQQKEE--AQLQESLGW------------AEQRAHQKVHQVTE---YEQELSSLlRDKRQE 1225
Cdd:pfam09787    1 NLESAKQELADYKQKAARILQSKEKliASLKEGSGVegldsstaltleLEELRQERDLLREEiqkLRGQIQQL-RTELQE 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1226 VEREHERKMDKMKEEhwqeMADARERYEAEERKqradllghltgelerlRRAHERELESMRQEQDQQLEDLRR------- 1298
Cdd:pfam09787   80 LEAQQQEEAESSREQ----LQELEEQLATERSA----------------RREAEAELERLQEELRYLEEELRRskatlqs 139

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 568959107  1299 RHRDHERKLQDLEVELSSRT------KDVKARLAQLNvqEENIRKEKQL 1341
Cdd:pfam09787  140 RIKDREAEIEKLRNQLTSKSqssssqSELENRLHQLT--ETLIQKQTML 186

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

1053-1310

6.34e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 51.49 E-value: 6.34e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1053 RAQVQSRTEAFENQIrTEQQAALQRLREEAETLQK--AERASLEQKSrraLEQLREQLEAEERSAQAALRAEKEAEKEAA 1130
Cdd:COG3096   845 RSELERELAQHRAQE-QQLRQQLDQLKEQLQLLNKllPQANLLADET---LADRLEELREELDAAQEAQAFIQQHGKALA 920

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1131 LLQ-----LR------EQLEGERKEAVAGLE--KKHSAELEQLCSSLEA-----------KHQEVISSLQKKIEGAqqkE 1186
Cdd:COG3096   921 QLEplvavLQsdpeqfEQLQADYLQAKEQQRrlKQQIFALSEVVQRRPHfsyedavgllgENSDLNEKLRARLEQA---E 997

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1187 EAQLQeslgwAEQRAHQKVHQVTEYEQELSSLL--RDKRQEVEREHERKMDKMKeehWQEMADARERyeAEERKQRadll 1264
Cdd:COG3096   998 EARRE-----AREQLRQAQAQYSQYNQVLASLKssRDAKQQTLQELEQELEELG---VQADAEAEER--ARIRRDE---- 1063

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 568959107 1265 ghLTGELERLrRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDL 1310
Cdd:COG3096  1064 --LHEELSQN-RSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQE 1106

Cast

pfam10174

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...

1052-1595

7.09e-06

Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 50.98 E-value: 7.09e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1052 LRAQVQSRTEAFENQIRTEQQAaLQRLREEAETLQKaeraslEQKSRRALEQLreqLEAEERSAQAALRAEKEAEKEAAL 1131
Cdd:pfam10174   47 LRKEEAARISVLKEQYRVTQEE-NQHLQLTIQALQD------ELRAQRDLNQL---LQQDFTTSPVDGEDKFSTPELTEE 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1132 LQLREQLEGERKEAVAGLEKKHSAELEqlcSSLEAKHQEVIS---SLQKKIEGAQQKEEAQLQESLGWAEQRahqkvhQV 1208
Cdd:pfam10174  117 NFRRLQSEHERQAKELFLLRKTLEEME---LRIETQKQTLGArdeSIKKLLEMLQSKGLPKKSGEEDWERTR------RI 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1209 TEYE---QELSSLLRDKrqEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRAdllghlTGELERLRRAHERELESM 1285
Cdd:pfam10174  188 AEAEmqlGHLEVLLDQK--EKENIHLREELHRRNQLQPDPAKTKALQTVIEMKDTK------ISSLERNIRDLEDEVQML 259

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1286 RQEQDQQLEDlrrrhrdHERKLQDLEVeLSSRTKDVKARLAQLNvQEENiRKEKQLLldaqrqaALEREEATATHQ---- 1361
Cdd:pfam10174  260 KTNGLLHTED-------REEEIKQMEV-YKSHSKFMKNKIDQLK-QELS-KKESELL-------ALQTKLETLTNQnsdc 322

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1362 --HLEEAKKEhthlLETKQQ----LRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNa 1435
Cdd:pfam10174  323 kqHIEVLKES----LTAKEQraaiLQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKIN- 397

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1436 sphpepGLH--IEDLrksldtnknQEVSSSLSLSKEEIDLSMESVRQFLSAEGVAVRNAKEFLVRQTRSMRRRQTALKAA 1513
Cdd:pfam10174  398 ------VLQkkIENL---------QEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQRERE 462

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1514 QQHWRHELASAQEVDEDLpgTEVLGNMRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKLIQLESSLQEEVSDEDTLKGSS 1593
Cdd:pfam10174  463 DRERLEELESLKKENKDL--KEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQL 540


                   ..
gi 568959107  1594 IK 1595
Cdd:pfam10174  541 KK 542

SCP-1

pfam05483

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...

1076-1359

8.38e-06

Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 50.88 E-value: 8.38e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1076 QRLREEAETLQKAErasleQKSRRALEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQlegerkeavaglekKHSA 1155
Cdd:pfam05483  530 ERMLKQIENLEEKE-----MNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKE--------------KQMK 590

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1156 ELEQLCSSLEAKhqevISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVhQVTEYEQELSSLlRDKRQEVEREHERKMD 1235
Cdd:pfam05483  591 ILENKCNNLKKQ----IENKNKNIEELHQENKALKKKGSAENKQLNAYEI-KVNKLELELASA-KQKFEEIIDNYQKEIE 664

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1236 --KMKEEHW-QEMADARERY-EAEERKQRADL-LGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDL 1310
Cdd:pfam05483  665 dkKISEEKLlEEVEKAKAIAdEAVKLQKEIDKrCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAAL 744

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 568959107  1311 EVELSsrtkDVKARLAQLNVQEENIRKEKQLLldaqrqaALEREEATAT 1359
Cdd:pfam05483  745 EIELS----NIKAELLSLKKQLEIEKEEKEKL-------KMEAKENTAI 782

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

1053-1323

1.04e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.76 E-value: 1.04e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1053 RAQVQSRTEAFENQIRtEQQAALQRLREEAETLQKaERASLEQKSRRALEQLREqLEAEERSAQAALRaekeaEKEAALL 1132
Cdd:COG4942    22 AAEAEAELEQLQQEIA-ELEKELAALKKEEKALLK-QLAALERRIAALARRIRA-LEQELAALEAELA-----ELEKEIA 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1133 QLREQLEgERKEAVAglekkhsaeleqlcssleakhqEVISSLQKKieGAQQKEEAQL-QESLGWAEQRAhQKVHQVTEY 1211
Cdd:COG4942    94 ELRAELE-AQKEELA----------------------ELLRALYRL--GRQPPLALLLsPEDFLDAVRRL-QYLKYLAPA 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1212 EQELSSLLRDKRQEVEReherkmdkmKEEHWQEMADARERYEAEERKQRADLLghltgELERLRRAHERELESMRQEQDQ 1291
Cdd:COG4942   148 RREQAEELRADLAELAA---------LRAELEAERAELEALLAELEEERAALE-----ALKAERQKLLARLEKELAELAA 213

                         250       260       270
                  ....*....|....*....|....*....|..
gi 568959107 1292 QLEDLRRRHRDHERKLQDLEVELSSRTKDVKA 1323
Cdd:COG4942   214 ELAELQQEAEELEALIARLEAEAAAAAERTPA 245

pfam00397

WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds ...

58-87

1.37e-05

WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds proline-rich peptide motifs in vitro.

Pssm-ID: 459800 [Multi-domain] Cd Length: 30 Bit Score: 43.26 E-value: 1.37e-05

                           10        20        30
                   ....*....|....*....|....*....|
gi 568959107    58 LPKGWKPCQNITGDLYYFNFDTGQSIWDHP 87
Cdd:pfam00397    1 LPPGWEERWDPDGRVYYYNHETGETQWEKP 30

PRK10929

putative mechanosensitive channel protein; Provisional

1182-1458

1.61e-05

putative mechanosensitive channel protein; Provisional

Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 50.05 E-value: 1.61e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1182 AQQKEEAQLQESLGWAE--QRAHQKvhQVTEYEQELSSLLRDKRQEVEREheRKMDKMKEEHWQEMADARERYEAEERKQ 1259
Cdd:PRK10929   20 ATAPDEKQITQELEQAKaaKTPAQA--EIVEALQSALNWLEERKGSLERA--KQYQQVIDNFPKLSAELRQQLNNERDEP 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1260 RADLLGHLTGELE-RLRRAHERELESMR---QEQD-------------QQLEDLRRRHRDHERKLQDLEvelSSRTKDVK 1322
Cdd:PRK10929   96 RSVPPNMSTDALEqEILQVSSQLLEKSRqaqQEQDrareisdslsqlpQQQTEARRQLNEIERRLQTLG---TPNTPLAQ 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1323 ARLAQLNVqEENIRKEKQLLLDAQRQAALEREEATatHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVE--LESqVDL 1400
Cdd:PRK10929  173 AQLTALQA-ESAALKALVDELELAQLSANNRQELA--RLRSELAKKRSQQLDAYLQALRNQLNSQRQREAEraLES-TEL 248

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568959107 1401 LQAQSQRLQKHLSSlEAEVQRK-QDVLKEMAAEMN--ASPHPEPGLHIEDLRKSLDTNKNQ 1458
Cdd:PRK10929  249 LAEQSGDLPKSIVA-QFKINRElSQALNQQAQRMDliASQQRQAASQTLQVRQALNTLREQ 308

Spc7

smart00787

Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...

1271-1423

2.04e-05

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.

Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 48.48 E-value: 2.04e-05

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107   1271 LERLRRAHERELESMRQEqDQQLedlrrrhRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRqaa 1350
Cdd:smart00787  142 LEGLKEGLDENLEGLKED-YKLL-------MKELELLNSIKPKLRDRKDALEEELRQLKQLEDELEDCDPTELDRAK--- 210

                            90       100       110       120       130       140       150
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568959107   1351 lerEEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDllQAQSQRLQ------KHLSSLEAEVQRKQ 1423
Cdd:smart00787  211 ---EKLKKLLQEIMIKVKKLEELEEELQELESKIEDLTNKKSELNTEIA--EAEKKLEQcrgftfKEIEKLKEQLKLLQ 284

PspA

COG1842

Phage shock protein A [Transcription, Signal transduction mechanisms];

1279-1436

2.44e-05

Phage shock protein A [Transcription, Signal transduction mechanisms];

Pssm-ID: 441447 [Multi-domain] Cd Length: 217 Bit Score: 47.51 E-value: 2.44e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1279 ERELESMRQEQDQQLEDLRR-------RHRDHERKLQDLEVELSSRTKdvKARLAqLNVQEENIRKEKqllldAQRQAAL 1351
Cdd:COG1842    25 EKMLDQAIRDMEEDLVEARQalaqviaNQKRLERQLEELEAEAEKWEE--KARLA-LEKGREDLAREA-----LERKAEL 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1352 ErEEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQsQRLQKHLSSLEAE--------VQRKQ 1423
Cdd:COG1842    97 E-AQAEALEAQLAQLEEQVEKLKEALRQLESKLEELKAKKDTLKARAKAAKAQ-EKVNEALSGIDSDdatsalerMEEKI 174

                         170
                  ....*....|...
gi 568959107 1424 DvlkEMAAEMNAS 1436
Cdd:COG1842   175 E---EMEARAEAA 184

growth_prot_Scy

polarized growth protein Scy;

1053-1409

2.49e-05

polarized growth protein Scy;

Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 49.44 E-value: 2.49e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1053 RAQVQSRTEAFENQIRTEQQAALQRLREEA---ETLQKAE--RASLEQKSRRALEQLReqleAEERSAQAALRAEKEAEK 1127
Cdd:NF041483  116 RLQAELHTEAVQRRQQLDQELAERRQTVEShvnENVAWAEqlRARTESQARRLLDESR----AEAEQALAAARAEAERLA 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1128 EAALLQLREQLEGERKEAVAGLeKKHSAELEQLCSSLEAKHQEVIS-SLQKKIEGAQQKEEA--QLQESLGWAEQRAhqk 1204
Cdd:NF041483  192 EEARQRLGSEAESARAEAEAIL-RRARKDAERLLNAASTQAQEATDhAEQLRSSTAAESDQArrQAAELSRAAEQRM--- 267

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1205 vhqvteyeQELSSLLRDKRQEVerehERKMDKMKEEHWQEMADARERYEAEER---KQRADLLGHLTGELERLRRAHERE 1281
Cdd:NF041483  268 --------QEAEEALREARAEA----EKVVAEAKEAAAKQLASAESANEQRTRtakEEIARLVGEATKEAEALKAEAEQA 335

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1282 LESMRQEQDQQLEDLRRRHR-----DHERKL----QDLEVELSSRTKDVKARLAQLNVQEENIRKEkqllldAQRQAALE 1352
Cdd:NF041483  336 LADARAEAEKLVAEAAEKARtvaaeDTAAQLakaaRTAEEVLTKASEDAKATTRAAAEEAERIRRE------AEAEADRL 409

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 568959107 1353 REEATATHQHLEEAKKEHThlletkqqlrrtiDDLRVRRVELESQVDLLQAQSQRLQ 1409
Cdd:NF041483  410 RGEAADQAEQLKGAAKDDT-------------KEYRAKTVELQEEARRLRGEAEQLR 453

WEMBL

pfam05701

Weak chloroplast movement under blue light; WEMBL consists of several plant proteins required ...

1222-1570

2.88e-05

Weak chloroplast movement under blue light; WEMBL consists of several plant proteins required for the chloroplast avoidance response under high intensity blue light. This avoidance response consists in the relocation of chloroplasts on the anticlinal side of exposed cells. Acts in association with PMI2 to maintain the velocity of chloroplast photo-relocation movement via the regulation of cp-actin filaments. Thus several member-sequences are described as "myosin heavy chain-like".

Pssm-ID: 461718 [Multi-domain] Cd Length: 562 Bit Score: 48.87 E-value: 2.88e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1222 KRQEVEREH--ERKMDKMKEEhwqeMADARERYE-AEERK-QRADLLGHLTGELERLRRAHER-ELESMRQEQDQQLEDL 1296
Cdd:pfam05701   30 RIQTVERRKlvELELEKVQEE----IPEYKKQSEaAEAAKaQVLEELESTKRLIEELKLNLERaQTEEAQAKQDSELAKL 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1297 RRRhrDHERKLQDLE-VELSSRTKDVKAR----LAQLN-VQEE--NIRKEKQLLLdAQRQAALER-EEATATHQHLEEAK 1367
Cdd:pfam05701  106 RVE--EMEQGIADEAsVAAKAQLEVAKARhaaaVAELKsVKEEleSLRKEYASLV-SERDIAIKRaEEAVSASKEIEKTV 182

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1368 KEHT-HLLETKQQL---RRTIDDLRVRRV---------ELESQVDLLQAQS--QRLQKHLSS---LEAEVQRKQDVLKEM 1429
Cdd:pfam05701  183 EELTiELIATKESLesaHAAHLEAEEHRIgaalareqdKLNWEKELKQAEEelQRLNQQLLSakdLKSKLETASALLLDL 262

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1430 AAEMNA---SPHPEPGLHIEDLRKSldTNKNQEVSSSLSLSKEEIDLSMESVRQFLSAEGVAVRNAKEFLVRQTR---SM 1503
Cdd:pfam05701  263 KAELAAymeSKLKEEADGEGNEKKT--STSIQAALASAKKELEEVKANIEKAKDEVNCLRVAAASLRSELEKEKAelaSL 340

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568959107  1504 RRRQT-------ALKAAQQHWRHELASAQEVDEDlpGTEVLGNMRKNLNEETRHLDEMKSAMRKGHDLLKK-KEE 1570
Cdd:pfam05701  341 RQREGmasiavsSLEAELNRTKSEIALVQAKEKE--AREKMVELPKQLQQAAQEAEEAKSLAQAAREELRKaKEE 413

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

996-1260

2.91e-05

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 49.20 E-value: 2.91e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107   996 QEEQDDSKSSIAEPQSKHTQGSESLLKAQLQKATAEEKEKEEETKIREEESRRLVCLRAQVQSRTEAFENQIRTEQQAAL 1075
Cdd:pfam02463  756 RLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEEL 835

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1076 QRLREEAETLQKAERASLEQKSR-----RALEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQLEGERKEAVagLE 1150
Cdd:pfam02463  836 EELALELKEEQKLEKLAEEELERleeeiTKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNL--LE 913

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1151 KKHSAELEQlcSSLEAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLLRDKRQEVEREH 1230
Cdd:pfam02463  914 EKENEIEER--IKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYN 991

                          250       260       270
                   ....*....|....*....|....*....|
gi 568959107  1231 ERKMDKMKEEhwQEMADARERYEAEERKQR 1260
Cdd:pfam02463  992 KDELEKERLE--EEKKKLIRAIIEETCQRL 1019

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

994-1587

2.96e-05

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 49.20 E-value: 2.96e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107   994 LDQEEQDDSKSSIAEPQSKhtqgseslLKAQLQKATAEEKEKEEetkireeesrrlvclraqVQSRTEAFENQI---RTE 1070
Cdd:pfam02463  311 DDEEKLKESEKEKKKAEKE--------LKKEKEEIEELEKELKE------------------LEIKREAEEEEEeelEKL 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1071 QQAALQRLREEAETLQKAERASLEQKSRRALEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQLEGERKEavAGLE 1150
Cdd:pfam02463  365 QEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEES--IELK 442

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1151 KKHSAELEQLCSSLEAKHQEVISSLQK--KIEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLLRDKRQEVER 1228
Cdd:pfam02463  443 QGKLTEEKEELEKQELKLLKDELELKKseDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGG 522

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1229 EHERKMDKMKEEHWQEMAD--ARERYEAEER---KQRADLLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDH 1303
Cdd:pfam02463  523 RIISAHGRLGDLGVAVENYkvAISTAVIVEVsatADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPI 602

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1304 ERKLQDLEVELSSRTKDVKARLAQLnvqeenIRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLLETKQQLRRT 1383
Cdd:pfam02463  603 LNLAQLDKATLEADEDDKRAKVVEG------ILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELL 676

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1384 IDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNASPHPEPGLHIEDLRKSLDTNKNQEVSSS 1463
Cdd:pfam02463  677 EIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSR 756

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1464 LSLSKEEIDLSMESVRQFLSAEGVAVRNAKEFLVRQTRSMRRRQTALKAAQQHWRHE---LASAQEVDEDLPGTEVLGNM 1540
Cdd:pfam02463  757 LKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEaelLEEEQLLIEQEEKIKEEELE 836

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 568959107  1541 RKNLNEETRHLDEMKSAMRKghDLLKKKEEKLIQLESSLQEEVSDED 1587
Cdd:pfam02463  837 ELALELKEEQKLEKLAEEEL--ERLEEEITKEELLQELLLKEEELEE 881

DR0291

COG1579

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

1207-1342

3.04e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 47.23 E-value: 3.04e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1207 QVTEYEQELSSLlRDKRQEVEREHErKMDKMKEEHWQEMADARERYEAEERKQR----ADLLGHLTGELERLRRAHErEL 1282
Cdd:COG1579    32 ELAELEDELAAL-EARLEAAKTELE-DLEKEIKRLELEIEEVEARIKKYEEQLGnvrnNKEYEALQKEIESLKRRIS-DL 108

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1283 ESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLL 1342
Cdd:COG1579   109 EDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREEL 168

RecN

COG0497

DNA repair ATPase RecN [Replication, recombination and repair];

1240-1436

3.37e-05

DNA repair ATPase RecN [Replication, recombination and repair];

Pssm-ID: 440263 [Multi-domain] Cd Length: 555 Bit Score: 48.53 E-value: 3.37e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1240 EHWQEMADARERYE-----AEERKQRADLLGHLTGELERLR-RAHErelesmrqeqDQQLEDLRRRHRDHER---KLQDL 1310
Cdd:COG0497   162 EAYRAWRALKKELEelradEAERARELDLLRFQLEELEAAAlQPGE----------EEELEEERRRLSNAEKlreALQEA 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1311 EVELSSRTKDVKARLAQLNVQEENIRKekqllLDAQRQAALER-EEATAthqHLEEAKKEHTHLLET------------- 1376
Cdd:COG0497   232 LEALSGGEGGALDLLGQALRALERLAE-----YDPSLAELAERlESALI---ELEEAASELRRYLDSlefdperleevee 303

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568959107 1377 -KQQLRR-------TIDDLRVRRVELESQVDLLQAQSQRLQKhlssLEAEVQRKQDVLKEMAAEMNAS 1436
Cdd:COG0497   304 rLALLRRlarkygvTVEELLAYAEELRAELAELENSDERLEE----LEAELAEAEAELLEAAEKLSAA 367

growth_prot_Scy

polarized growth protein Scy;

1059-1365

3.49e-05

polarized growth protein Scy;

Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 49.05 E-value: 3.49e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1059 RTEAFE--NQIRTEQQAALQRLREEaetlqkAERASLEQKSRRALEQLREQLEAEERSAQAalraekeaekEAALLQLRE 1136
Cdd:NF041483  537 RAEAEEqaEEVRAAAERAARELREE------TERAIAARQAEAAEELTRLHTEAEERLTAA----------EEALADARA 600

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1137 QLEGERKEAVAGLEKkhsaeleqlcssLEAKHQEVISSLQkkiegAQQKEEAQLQESLGWAEQRAHQkvhqvTEYEQELS 1216
Cdd:NF041483  601 EAERIRREAAEETER------------LRTEAAERIRTLQ-----AQAEQEAERLRTEAAADASAAR-----AEGENVAV 658

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1217 SLLRDKRQEVER---EHERKMDKMKeehwQEMADARERYEAEErkqrADLLGHLTGELERLRRAHERELESMRQEQDQQl 1293
Cdd:NF041483  659 RLRSEAAAEAERlksEAQESADRVR----AEAAAAAERVGTEA----AEALAAAQEEAARRRREAEETLGSARAEADQE- 729

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568959107 1294 edlRRRHRDherklQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEE 1365
Cdd:NF041483  730 ---RERARE-----QSEELLASARKRVEEAQAEAQRLVEEADRRATELVSAAEQTAQQVRDSVAGLQEQAEE 793

rad50

TIGR00606

rad50; All proteins in this family for which functions are known are involvedin recombination, ...

1198-1587

3.67e-05

Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 48.89 E-value: 3.67e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1198 EQRAHQKVHQVTEYEQELSSLLRDK--RQEVEREHERKMDKMKEEHWQEMADARERYEaEERKQRADLLGHLTG------ 1269
Cdd:TIGR00606  201 KVQEHQMELKYLKQYKEKACEIRDQitSKEAQLESSREIVKSYENELDPLKNRLKEIE-HNLSKIMKLDNEIKAlksrkk 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1270 ELERLRRAHERELESMRQEQDQQLEDLRRRH----RDHERKLQDLEVELSSRTKDVK-------------ARLA-QLNVQ 1331
Cdd:TIGR00606  280 QMEKDNSELELKMEKVFQGTDEQLNDLYHNHqrtvREKERELVDCQRELEKLNKERRllnqektellveqGRLQlQADRH 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1332 EENIRKEKQLLLDAQRQAALEREEATATHQhlEEAKKEHTHLLETKQQLRRTIDDLRVrrvELESQVDLLQAQSQRLQKH 1411
Cdd:TIGR00606  360 QEHIRARDSLIQSLATRLELDGFERGPFSE--RQIKNFHTLVIERQEDEAKTAAQLCA---DLQSKERLKQEQADEIRDE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1412 LSSLEAEVQRKQDVLKEMAAEM--------NASPHPEPGLHIED-LRKSL-DTNKNQEVSSSLSLSKEEIDLSMESVRQF 1481
Cdd:TIGR00606  435 KKGLGRTIELKKEILEKKQEELkfvikelqQLEGSSDRILELDQeLRKAErELSKAEKNSLTETLKKEVKSLQNEKADLD 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1482 LS----AEGVAVRNAKEFLVRQTRSMRRRQTalKAAQQ----HWRHELASAQEVDeDLPGTEVLGN-----------MRK 1542
Cdd:TIGR00606  515 RKlrklDQEMEQLNHHTTTRTQMEMLTKDKM--DKDEQirkiKSRHSDELTSLLG-YFPNKKQLEDwlhskskeinqTRD 591

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*...
gi 568959107  1543 NL---NEETRHLDEMKSAMRKGhdlLKKKEEKLIQLESSLQEEVSDED 1587
Cdd:TIGR00606  592 RLaklNKELASLEQNKNHINNE---LESKEEQLSSYEDKLFDVCGSQD 636

PspA_IM30

pfam04012

PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent ...

1052-1195

3.86e-05

Pssm-ID: 461130 [Multi-domain] Cd Length: 215 Bit Score: 46.98 E-value: 3.86e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1052 LRAQVQSRTEAFENQIRTEQQAalqrLREEAETLQKAERASLEQKSR-----RALEQLREQLEAEERSAQAALRaEKEAE 1126
Cdd:pfam04012    9 VRANIHEGLDKAEDPEKMLEQA----IRDMQSELVKARQALAQTIARqkqleRRLEQQTEQAKKLEEKAQAALT-KGNEE 83

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568959107  1127 KEAALLQLREQLEG--ERKEAVAGLEKKHSAELEQLCSSLEAKHQEVISSLQK-KIEGAQQKEEAQLQESLG 1195
Cdd:pfam04012   84 LAREALAEKKSLEKqaEALETQLAQQRSAVEQLRKQLAALETKIQQLKAKKNLlKARLKAAKAQEAVQTSLG 155

PspA

COG1842

Phage shock protein A [Transcription, Signal transduction mechanisms];

1052-1289

3.91e-05

Phage shock protein A [Transcription, Signal transduction mechanisms];

Pssm-ID: 441447 [Multi-domain] Cd Length: 217 Bit Score: 46.74 E-value: 3.91e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1052 LRAQVQSRTEAFENQIRTEQQAalqrLREEAETLQKAERASLEQK-SRRALEQLREQLEAE----ERSAQAALRAEkeae 1126
Cdd:COG1842    10 IRANINALLDKAEDPEKMLDQA----IRDMEEDLVEARQALAQVIaNQKRLERQLEELEAEaekwEEKARLALEKG---- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1127 keaallqlREQLegerkeAVAGLEKKhsAELEQLCSSLEAKHQevisslqkkiegAQQKEEAQLQESLgwaeQRAHQKvh 1206
Cdd:COG1842    82 --------REDL------AREALERK--AELEAQAEALEAQLA------------QLEEQVEKLKEAL----RQLESK-- 127

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1207 qVTEYEQELSSLL-RDKRQEVEREHERKMDKMKEEhwqEMADARERYEA--EERKQRADLLGHLTG------ELERLRRA 1277
Cdd:COG1842   128 -LEELKAKKDTLKaRAKAAKAQEKVNEALSGIDSD---DATSALERMEEkiEEMEARAEAAAELAAgdslddELAELEAD 203

                         250
                  ....*....|....
gi 568959107 1278 H--ERELESMRQEQ 1289
Cdd:COG1842   204 SevEDELAALKAKM 217

DUF4515

pfam14988

Domain of unknown function (DUF4515); This family of proteins is found in bacteria and ...

1225-1421

4.15e-05

Domain of unknown function (DUF4515); This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 198 and 469 amino acids in length. There are two completely conserved L residues that may be functionally important.

Pssm-ID: 405647 [Multi-domain] Cd Length: 206 Bit Score: 46.68 E-value: 4.15e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1225 EVEREHERKMDKMKEEHWQEMADAREryEAEERKQR-ADLLGHLTGELERLRRAHERELESMRQEQdQQLEDLRRRHRDH 1303
Cdd:pfam14988    7 EYLAKKTEEKQKKIEKLWNQYVQECE--EIERRRQElASRYTQQTAELQTQLLQKEKEQASLKKEL-QALRPFAKLKESQ 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1304 ERKLQDLEVELSSRTKDVKARLAQLNVQeenIRKEKQLLldaQRQAALEREEATATHQHLEEAKKEHTHLLETKQQLRRT 1383
Cdd:pfam14988   84 EREIQDLEEEKEKVRAETAEKDREAHLQ---FLKEKALL---EKQLQELRILELGERATRELKRKAQALKLAAKQALSEF 157

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 568959107  1384 IDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQR 1421
Cdd:pfam14988  158 CRSIKRENRQLQKELLQLIQETQALEAIKSKLENRKQR 195

cd00201

Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ...

59-89

5.04e-05

Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 41.74 E-value: 5.04e-05

                          10        20        30
                  ....*....|....*....|....*....|.
gi 568959107   59 PKGWKPCQNITGDLYYFNFDTGQSIWDHPCD 89
Cdd:cd00201     1 PPGWEERWDPDGRVYYYNHNTKETQWEDPRE 31

mukB

chromosome partition protein MukB;

1199-1435

6.01e-05

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 48.41 E-value: 6.01e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1199 QRAHQKVHQV----------TEYEQELSsLLRDKRQEVEREherkmdkmKEEHWQEMADARERYEAEerKQRADLLGHLT 1268
Cdd:PRK04863  813 QRLHQAFSRFigshlavafeADPEAELR-QLNRRRVELERA--------LADHESQEQQQRSQLEQA--KEGLSALNRLL 881

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1269 GELERLRR-AHERELESMRqEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKD------VKARLAQLNVQEENIRKEKQL 1341
Cdd:PRK04863  882 PRLNLLADeTLADRVEEIR-EQLDEAEEAKRFVQQHGNALAQLEPIVSVLQSDpeqfeqLKQDYQQAQQTQRDAKQQAFA 960

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1342 LLD-AQRQAALEREEATathQHLEEAKkehthllETKQQLRRTIDDLRVRRVELESQvdLLQAQSQRLQKH--LSSLEAE 1418
Cdd:PRK04863  961 LTEvVQRRAHFSYEDAA---EMLAKNS-------DLNEKLRQRLEQAEQERTRAREQ--LRQAQAQLAQYNqvLASLKSS 1028

                         250
                  ....*....|....*..
gi 568959107 1419 VQRKQDVLKEMAAEMNA 1435
Cdd:PRK04863 1029 YDAKRQMLQELKQELQD 1045

PRK12704

phosphodiesterase; Provisional

1057-1201

6.02e-05

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 47.85 E-value: 6.02e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1057 QSRTEAFENQIRTEQQAALQRLREEAETLQKAERASLEQKSRRaLEQLREQLEaeERSAQAALRAEKEAEKEAALLQLRE 1136
Cdd:PRK12704   48 KKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKR-LLQKEENLD--RKLELLEKREEELEKKEKELEQKQQ 124

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568959107 1137 QLEgERKEAVAGLEKKHSAELEQLcSSL---EAKhQEVISSLQKKIEGAQQK------EEAQLQeslgwAEQRA 1201
Cdd:PRK12704  125 ELE-KKEEELEELIEEQLQELERI-SGLtaeEAK-EILLEKVEEEARHEAAVlikeieEEAKEE-----ADKKA 190

Cast

pfam10174

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...

1070-1361

6.06e-05

Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 47.89 E-value: 6.06e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1070 EQQAALQRLREEAETLQKAERASLEQkSRRALEQLREQLEA-----EERSA-------QAALRAEKEAEKEAALLQLREQ 1137
Cdd:pfam10174  447 EKERIIERLKEQREREDRERLEELES-LKKENKDLKEKVSAlqpelTEKESslidlkeHASSLASSGLKKDSKLKSLEIA 525

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1138 LEGERKEAVA---GLEKKHSAELEQLCS---SLEAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEY 1211
Cdd:pfam10174  526 VEQKKEECSKlenQLKKAHNAEEAVRTNpeiNDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAEL 605

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1212 EQELSSLLRDKRQEVeREHERKMDKMKEEHWQEMADARERYEAEERKQRADLLGHLTGELERLRR---AHERELESMRQ- 1287
Cdd:pfam10174  606 ESLTLRQMKEQNKKV-ANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQLQLEELMGALEKTRQeldATKARLSSTQQs 684

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1288 --EQDQQLEDLRrrhrdHERKLQdLEVELSSRTkdvKARLAQLNVQEENI--------RKEKqlllDAQRQAALEREEAT 1357
Cdd:pfam10174  685 laEKDGHLTNLR-----AERRKQ-LEEILEMKQ---EALLAAISEKDANIallelsssKKKK----TQEEVMALKREKDR 751


                   ....
gi 568959107  1358 ATHQ 1361
Cdd:pfam10174  752 LVHQ 755

DUF3584

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

1134-1597

7.03e-05

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 47.91 E-value: 7.03e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1134 LREQLEGERKEAVAGLEKKHSAELEQLcSSLEAKhqevISSLQKKIEGAQQKEEAQLQEslgwaeQRAHQKvhqvtEYEQ 1213
Cdd:pfam12128  227 IRDIQAIAGIMKIRPEFTKLQQEFNTL-ESAELR----LSHLHFGYKSDETLIASRQEE------RQETSA-----ELNQ 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1214 ELSSLLRDKRQEVEREHER----KMDKMKEEHWQEMADAR----ERYEAEERKQRADLLGHLTGELERLRRAHERELESm 1285
Cdd:pfam12128  291 LLRTLDDQWKEKRDELNGElsaaDAAVAKDRSELEALEDQhgafLDADIETAAADQEQLPSWQSELENLEERLKALTGK- 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1286 rqeqdqqledlrrrHRDHERKLQDLEVELSSRTKDVkarLAQLNVQEENIRKEKQLLLDAQRqAALEREEATATHQH--- 1362
Cdd:pfam12128  370 --------------HQDVTAKYNRRRSKIKEQNNRD---IAGIKDKLAKIREARDRQLAVAE-DDLQALESELREQLeag 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1363 --------------LEEAK---KEHTHLLETKQQLRRTIDDLRVRRVELES--------QVDLLQAQSQRLQ--KHLSSL 1415
Cdd:pfam12128  432 klefneeeyrlksrLGELKlrlNQATATPELLLQLENFDERIERAREEQEAanaeverlQSELRQARKRRDQasEALRQA 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1416 EAEVQRKQDVLKEMAAEMNasphPEPGLHIEDLRKSLDTNKNQ--EVSSSLSLSKEEID--LSMESVRQFLSAEGVAVR- 1490
Cdd:pfam12128  512 SRRLEERQSALDELELQLF----PQAGTLLHFLRKEAPDWEQSigKVISPELLHRTDLDpeVWDGSVGGELNLYGVKLDl 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1491 ---NAKEFlVRQTRSMRRRQTALKAAQQHwRHELASAQEvdedlpgtEVLGNMRKNLNEETRHLDEMKSAMRKGHDLLKK 1567
Cdd:pfam12128  588 kriDVPEW-AASEEELRERLDKAEEALQS-AREKQAAAE--------EQLVQANGELEKASREETFARTALKNARLDLRR 657

                          490       500       510
                   ....*....|....*....|....*....|
gi 568959107  1568 KEEKLIQLESSLQEEVSDEDTLKGSSIKKV 1597
Cdd:pfam12128  658 LFDEKQSEKDKKNKALAERKDSANERLNSL 687

sbcc

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

1052-1311

7.34e-05

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 48.04 E-value: 7.34e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1052 LRAQVQSRTEAFENQIRTEQQAALQRLReeAETLQKAERaslEQKSRRALEQLREQLeAEERSAQAALRAEKEAEKEAAL 1131
Cdd:TIGR00618  604 SEAEDMLACEQHALLRKLQPEQDLQDVR--LHLQQCSQE---LALKLTALHALQLTL-TQERVREHALSIRVLPKELLAS 677

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1132 LQLREQLEGERKEAVAG----LEKKHSAELEQLCSSLEAKH-----QEVISSLQKKIEGaqqkEEAQLQESLGWAE-QRA 1201
Cdd:TIGR00618  678 RQLALQKMQSEKEQLTYwkemLAQCQTLLRELETHIEEYDRefneiENASSSLGSDLAA----REDALNQSLKELMhQAR 753

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1202 HQKVHQVTEYEQELSSLLRDKRQEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRADLLGHLTGELERLRRAHErE 1281
Cdd:TIGR00618  754 TVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEE-Q 832

                          250       260       270
                   ....*....|....*....|....*....|
gi 568959107  1282 LESMRQEQDQQLEDLRRRHRDHERKLQDLE 1311
Cdd:TIGR00618  833 FLSRLEEKSATLGEITHQLLKYEECSKQLA 862

Myosin_tail_1

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

1069-1582

7.38e-05

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 47.86 E-value: 7.38e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1069 TEQQAALQRLREEaetLQKA-ERASLEQKSRRALEQLREQLEAEERsaqaalraekeaekeaallQLREQLEGErkeava 1147
Cdd:pfam01576    1 TRQEEEMQAKEEE---LQKVkERQQKAESELKELEKKHQQLCEEKN-------------------ALQEQLQAE------ 52

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1148 gleKKHSAELEQLCSSLEAKHQE---VISSLQKKIEgaqqkEEAQLQESLGWAEQRAHQkvhQVTEYEQELSSLlRDKRQ 1224
Cdd:pfam01576   53 ---TELCAEAEEMRARLAARKQEleeILHELESRLE-----EEEERSQQLQNEKKKMQQ---HIQDLEEQLDEE-EAARQ 120

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1225 EVEREH---ERKMDKMkEEHWQEMADA-----RERYEAEERKqrADLLGHLTGE------LERLRRAHERELESMrQEQD 1290
Cdd:pfam01576  121 KLQLEKvttEAKIKKL-EEDILLLEDQnsklsKERKLLEERI--SEFTSNLAEEeekaksLSKLKNKHEAMISDL-EERL 196

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1291 QQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQeeNIRKEKQLlldaqrQAALER--EEATATHQHLEEAKK 1368
Cdd:pfam01576  197 KKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQ--LAKKEEEL------QAALARleEETAQKNNALKKIRE 268

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1369 EHTHLLETKQQL-------------RRTI-DDLRVRRVELESQVDLLQAQ----SQRLQK--HLS-SLEAEVQRKQDVLK 1427
Cdd:pfam01576  269 LEAQISELQEDLeseraarnkaekqRRDLgEELEALKTELEDTLDTTAAQqelrSKREQEvtELKkALEEETRSHEAQLQ 348

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1428 EMAAEMNASphpepglhIEDLRKSLDTNKNQEVSSslslskEEIDLSMESVRQFLSAEGVAVRNAKeflvrqTRSMRRRQ 1507
Cdd:pfam01576  349 EMRQKHTQA--------LEELTEQLEQAKRNKANL------EKAKQALESENAELQAELRTLQQAK------QDSEHKRK 408

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568959107  1508 TaLKAAQQHWRHELASAQEVDEDLpgTEVLGNMRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKLIQLESSLQEE 1582
Cdd:pfam01576  409 K-LEGQLQELQARLSESERQRAEL--AEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEE 480

growth_prot_Scy

polarized growth protein Scy;

1060-1588

7.57e-05

polarized growth protein Scy;

Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 47.90 E-value: 7.57e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1060 TEAFENQIRTEQQAAlqRLREEAETLQKAERASLEQKSRRALEQLREQLEA-----EERSAQAALRAEKEAEKEAALLQL 1134
Cdd:NF041483  695 TEAAEALAAAQEEAA--RRRREAEETLGSARAEADQERERAREQSEELLASarkrvEEAQAEAQRLVEEADRRATELVSA 772

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1135 REQLEGERKEAVAGLEKKHSAELEQLCSSLEAKHQEVISSLQK-----KIEGAQQKEEA---------QLQESLGWAEQR 1200
Cdd:NF041483  773 AEQTAQQVRDSVAGLQEQAEEEIAGLRSAAEHAAERTRTEAQEeadrvRSDAYAERERAsedanrlrrEAQEETEAAKAL 852

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1201 AHQKVHQVTEYEQELSSLLRDKRQEVEREHERKMDKMKEEHWQEMADARE---RYEAEERKQRADLLGHLTGELERLRRA 1277
Cdd:NF041483  853 AERTVSEAIAEAERLRSDASEYAQRVRTEASDTLASAEQDAARTRADAREdanRIRSDAAAQADRLIGEATSEAERLTAE 932

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1278 HERELESMRQEQDQQLEdlrRRHRDHERKLQDLEVELSSRTKDVKARLAQLnvqeenirkekqlLLDAQRQAALEREEAt 1357
Cdd:NF041483  933 ARAEAERLRDEARAEAE---RVRADAAAQAEQLIAEATGEAERLRAEAAET-------------VGSAQQHAERIRTEA- 995

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1358 atHQHLEEAKKEHTHLL-ETKQQLRRTIDDLRV----RRVELESQVDLLQAQSQRLQKHLssleaeVQRKQDVLKEMAAE 1432
Cdd:NF041483  996 --ERVKAEAAAEAERLRtEAREEADRTLDEARKdankRRSEAAEQADTLITEAAAEADQL------TAKAQEEALRTTTE 1067

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1433 MNAsphpepglhiedlrksldtnknQEVSSSLSLSKEEIDLSMESVRQFLSAEGVAVRNAKEFLVrqtrSMRRRQTALKA 1512
Cdd:NF041483 1068 AEA----------------------QADTMVGAARKEAERIVAEATVEGNSLVEKARTDADELLV----GARRDATAIRE 1121

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568959107 1513 AQQHWRHELASaqEVDEdlpgtevlgnmrknLNEETRH--LDEMKSAMRKGHDLLKKKEEKLIQLESSLQEEVSDEDT 1588
Cdd:NF041483 1122 RAEELRDRITG--EIEE--------------LHERARResAEQMKSAGERCDALVKAAEEQLAEAEAKAKELVSDANS 1183

CCDC22

pfam05667

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...

1064-1274

9.90e-05

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.

Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 47.33 E-value: 9.90e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1064 ENQIRTEQQAALQRLREEAETLQ------KAERASLEQKSRRALEQLRE-QLEAEERSAQaalraekeaekeaalLQLRE 1136
Cdd:pfam05667  326 EEELQQQREEELEELQEQLEDLEssiqelEKEIKKLESSIKQVEEELEElKEQNEELEKQ---------------YKVKK 390

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1137 QLEGERKEAVAGLEKkhsaeLEQLCSSleakhqevisSLQKKIEGAQQKEEaqlqeslgwaeqrahqkvHQVT---EYEQ 1213
Cdd:pfam05667  391 KTLDLLPDAEENIAK-----LQALVDA----------SAQRLVELAGQWEK------------------HRVPlieEYRA 437

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568959107  1214 elsslLRDKRQEVEREHERKMDKMKEEHwQEMADAreryeAEERKQRADLLGHLTGELERL 1274
Cdd:pfam05667  438 -----LKEAKSNKEDESQRKLEEIKELR-EKIKEV-----AEEAKQKEELYKQLVAEYERL 487

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

1082-1366

1.05e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 47.32 E-value: 1.05e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1082 AETLQKAERASLEQKSRRALEQLREQL-EAEERSAQAALRaekeaekeaaLLQLREQlegerkEAVAGLEKKHSAELEQL 1160
Cdd:COG3206   158 AEAYLEQNLELRREEARKALEFLEEQLpELRKELEEAEAA----------LEEFRQK------NGLVDLSEEAKLLLQQL 221

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1161 cSSLEAKhqevISSLQKKIEGAQQKEEaQLQESLGWAEQRAhQKVHQVTEYEQelsslLRDKRQEVEREHERKMDKMKEE 1240
Cdd:COG3206   222 -SELESQ----LAEARAELAEAEARLA-ALRAQLGSGPDAL-PELLQSPVIQQ-----LRAQLAELEAELAELSARYTPN 289

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1241 HwQEMADAREryeaeerkQRADLLGHLTGELERLRRAHERELESMRQeQDQQLEDLRRRHRDHERKLQDLEVELSSRTKD 1320
Cdd:COG3206   290 H-PDVIALRA--------QIAALRAQLQQEAQRILASLEAELEALQA-REASLQAQLAQLEARLAELPELEAELRRLERE 359

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 568959107 1321 VKARLAQLnvqeenirkekQLLLDAQRQAALEREEATATHQHLEEA 1366
Cdd:COG3206   360 VEVARELY-----------ESLLQRLEEARLAEALTVGNVRVIDPA 394

RNase_Y_N

pfam12072

RNase Y N-terminal region;

1227-1372

1.05e-04

RNase Y N-terminal region;

Pssm-ID: 463456 [Multi-domain] Cd Length: 201 Bit Score: 45.26 E-value: 1.05e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1227 EREHERKMDKMKEEHWQEMADAREryEAEERKQRADLLGHltGELERLRRAHEREL-----ESMRQEQ---------DQQ 1292
Cdd:pfam12072   22 KSIAEAKIGSAEELAKRIIEEAKK--EAETKKKEALLEAK--EEIHKLRAEAERELkerrnELQRQERrllqkeetlDRK 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1293 LEDLRRRhrdhERKLQDLEVELSSRTKDVKARLAQLnvqEENIRKEKQLLldaQRQAALEREEATAthQHLEEAKKEHTH 1372
Cdd:pfam12072   98 DESLEKK----EESLEKKEKELEAQQQQLEEKEEEL---EELIEEQRQEL---ERISGLTSEEAKE--ILLDEVEEELRH 165

PKK

pfam12474

Polo kinase kinase; This domain family is found in eukaryotes, and is approximately 140 amino ...

1203-1310

1.14e-04

Polo kinase kinase; This domain family is found in eukaryotes, and is approximately 140 amino acids in length. The family is found in association with pfam00069. Polo-like kinase 1 (Plx1) is essential during mitosis for the activation of Cdc25C, for spindle assembly, and for cyclin B degradation. This family is Polo kinase kinase (PKK) which phosphorylates Polo kinase and Polo-like kinase to activate them. PKK is a serine/threonine kinase.

Pssm-ID: 463600 [Multi-domain] Cd Length: 139 Bit Score: 44.09 E-value: 1.14e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1203 QKVHQVTEYEQELSSLLRDKRQEVE---REHERKMDKMKEEHWQEMADA--RERYEAEER--------KQRADLlghLTG 1269
Cdd:pfam12474    4 QKEQQKDRFEQERQQLKKRYEKELEqleRQQKQQIEKLEQRQTQELRRLpkRIRAEQKKRlkmfreslKQEKKE---LKQ 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 568959107  1270 ELERLRRAHERELESMRQEQ------DQQLEDLRRRHRDHERKLQDL 1310
Cdd:pfam12474   81 EVEKLPKFQRKEAKRQRKEEleleqkHEELEFLQAQSEALERELQQL 127

mukB

chromosome partition protein MukB;

1098-1418

1.36e-04

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 47.26 E-value: 1.36e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1098 RRALEQLREQLEAEersaqaalraekeaekeaallqlREQLEGERKEAVAGLEKKHSaeLEQLCSSLEAKHQEVisSLQK 1177
Cdd:PRK04863  781 RAAREKRIEQLRAE-----------------------REELAERYATLSFDVQKLQR--LHQAFSRFIGSHLAV--AFEA 833

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1178 KIEGAQQKEEAQLQEslgwaeqrAHQKVHQVTEYEQELSSLLRDKRQEVE--REHERKMDKMKEEHWQEMADA--RERYE 1253
Cdd:PRK04863  834 DPEAELRQLNRRRVE--------LERALADHESQEQQQRSQLEQAKEGLSalNRLLPRLNLLADETLADRVEEirEQLDE 905

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1254 AEERKQRADLLGHLTGELER--------------LRRAHErELESMRQEQDQQLEDL-----RRRHRDHERKLQDL--EV 1312
Cdd:PRK04863  906 AEEAKRFVQQHGNALAQLEPivsvlqsdpeqfeqLKQDYQ-QAQQTQRDAKQQAFALtevvqRRAHFSYEDAAEMLakNS 984

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1313 ELSSRtkdVKARLAQLNVQEENIRkekqlllDAQRQAaleREEATATHQHLEEAKKEHTHLLETKQQLRRTIDDL----- 1387
Cdd:PRK04863  985 DLNEK---LRQRLEQAEQERTRAR-------EQLRQA---QAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLgvpad 1051

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 568959107 1388 -------RVRRVELESQvdLLQAQSQR--LQKHLSSLEAE 1418
Cdd:PRK04863 1052 sgaeeraRARRDELHAR--LSANRSRRnqLEKQLTFCEAE 1089

PRK12704

phosphodiesterase; Provisional

1279-1433

1.45e-04

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 46.69 E-value: 1.45e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1279 ERELESMRQEQDQQLEDlrrrhRDHERKlQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLldaqrqaalereeata 1358
Cdd:PRK12704   48 KKEAEAIKKEALLEAKE-----EIHKLR-NEFEKELRERRNELQKLEKRLLQKEENLDRKLELL---------------- 105

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568959107 1359 thqhleeaKKEHTHLLETKQQLRRTIDDLRVRRVELEsqvDLLQAQSQRLQkHLSSLEAEvQRKQDVLKEMAAEM 1433
Cdd:PRK12704  106 --------EKREEELEKKEKELEQKQQELEKKEEELE---ELIEEQLQELE-RISGLTAE-EAKEILLEKVEEEA 167

tolA_full

TIGR02794

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

1060-1285

1.62e-04

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 45.99 E-value: 1.62e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1060 TEAFENQIRTEQQAALQRLREEAETLQKAERASLEQKSRRALEQLREQLEAEERSAQAALRAEKeaekeaallQLREQLE 1139
Cdd:TIGR02794   45 PGAVAQQANRIQQQKKPAAKKEQERQKKLEQQAEEAEKQRAAEQARQKELEQRAAAEKAAKQAE---------QAAKQAE 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1140 GERKEAVaglEKKHSAELEQlcssleAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQVteyEQElssll 1219
Cdd:TIGR02794  116 EKQKQAE---EAKAKQAAEA------KAKAEAEAERKAKEEAAKQAEEEAKAKAAAEAKKKAEEAKKKA---EAE----- 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568959107  1220 RDKRQEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRADllghltgELERLRRAHERELESM 1285
Cdd:TIGR02794  179 AKAKAEAEAKAKAEEAKAKAEAAKAKAAAEAAAKAEAEAAAAA-------AAEAERKADEAELGDI 237

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

1070-1425

1.80e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 46.87 E-value: 1.80e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1070 EQQAALqrLREEAETL--QKAERASLEQKSRRALEQLREQL------------EAEERSAQAALR--AEKEAEKEAALLQ 1133
Cdd:COG3096   784 EKRLEE--LRAERDELaeQYAKASFDVQKLQRLHQAFSQFVgghlavafapdpEAELAALRQRRSelERELAQHRAQEQQ 861

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1134 LREQLEgERKEAVAGLEKKhsaeLEQLCSSLEAKHQEVISSLQKKIEGAQQKEeaqlqeslgwAEQRAHQKvhQVTEYEQ 1213
Cdd:COG3096   862 LRQQLD-QLKEQLQLLNKL----LPQANLLADETLADRLEELREELDAAQEAQ----------AFIQQHGK--ALAQLEP 924

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1214 ELSSLLRDKRQ--EVEREHERKMDKMKEEHWQ--EMADARERYEAEERKQRADLLGHLTGELERLRrAHERELESMRQEQ 1289
Cdd:COG3096   925 LVAVLQSDPEQfeQLQADYLQAKEQQRRLKQQifALSEVVQRRPHFSYEDAVGLLGENSDLNEKLR-ARLEQAEEARREA 1003

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1290 DQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKA---RLAQLNVQEENirkekqlllDAQRQAALEREEatathqhleea 1366
Cdd:COG3096  1004 REQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQEleqELEELGVQADA---------EAEERARIRRDE----------- 1063

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568959107 1367 kkehthlleTKQQLRRTiddlRVRRVELESQVDLLQAQSQRLQKHLSSLEAE--VQRKQDV 1425
Cdd:COG3096  1064 ---------LHEELSQN----RSRRSQLEKQLTRCEAEMDSLQKRLRKAERDykQEREQVV 1111

PRK11281

mechanosensitive channel MscK;

1160-1432

1.84e-04

mechanosensitive channel MscK;

Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 46.44 E-value: 1.84e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1160 LCSSLEAKHQEVISSLQKKIEGAQQKEEAQLQESLGwAEQRAHQKVhqvteYEQELSSLlrDKRQEVEREHErKMDKMKE 1239
Cdd:PRK11281   20 LCLSSAFARAASNGDLPTEADVQAQLDALNKQKLLE-AEDKLVQQD-----LEQTLALL--DKIDRQKEETE-QLKQQLA 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1240 EHWQEMADARERYEAEERKQRADLLghltgelERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLqdleVELSSRTK 1319
Cdd:PRK11281   91 QAPAKLRQAQAELEALKDDNDEETR-------ETLSTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQL----VSLQTQPE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1320 DVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEEAKKE-HTHLLETKQQLRrtidDLrvrrveLESQV 1398
Cdd:PRK11281  160 RAQAALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDlQRKSLEGNTQLQ----DL------LQKQR 229

                         250       260       270
                  ....*....|....*....|....*....|....
gi 568959107 1399 DLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAE 1432
Cdd:PRK11281  230 DYLTARIQRLEHQLQLLQEAINSKRLTLSEKTVQ 263

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

1061-1180

1.88e-04

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 45.65 E-value: 1.88e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1061 EAFENQIRTEQQAALQRLREEAETLQKAERASLEQKSRRA-LEQLREQLEAEERSAQAALRaekeaekeaallQLREQLE 1139
Cdd:cd16269   180 EAEAEAILQADQALTEKEKEIEAERAKAEAAEQERKLLEEqQRELEQKLEDQERSYEEHLR------------QLKEKME 247

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 568959107 1140 GERKEAVAGLEKKHSAELEQLCSSLEAKHQEVISSLQKKIE 1180
Cdd:cd16269   248 EERENLLKEQERALESKLKEQEALLEEGFKEQAELLQEEIR 288

PRK11637

AmiB activator; Provisional

1243-1429

2.15e-04

AmiB activator; Provisional

Pssm-ID: 236942 [Multi-domain] Cd Length: 428 Bit Score: 45.84 E-value: 2.15e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1243 QEMAdARERYEAEERKQRADLLGHLtgelerlrraherelesmrQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVK 1322
Cdd:PRK11637   54 QDIA-AKEKSVRQQQQQRASLLAQL-------------------KKQEEAISQASRKLRETQNTLNQLNKQIDELNASIA 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1323 ARLAQLNVQ--------------------------EENIRKEKQL----LLDAQRQAALE-----REEATATHQHLEEAK 1367
Cdd:PRK11637  114 KLEQQQAAQerllaaqldaafrqgehtglqlilsgEESQRGERILayfgYLNQARQETIAelkqtREELAAQKAELEEKQ 193

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568959107 1368 KEHTHLLETKQQlrrtiddlrvrrveleSQVDLLQAQSQRlQKHLSSLEAEVQRKQDVLKEM 1429
Cdd:PRK11637  194 SQQKTLLYEQQA----------------QQQKLEQARNER-KKTLTGLESSLQKDQQQLSEL 238

PRK12705

hypothetical protein; Provisional

1243-1382

2.32e-04

hypothetical protein; Provisional

Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 45.86 E-value: 2.32e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1243 QEMADARERYEAEERKQRADLLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDHER---KLQDLEVELSSRTK 1319
Cdd:PRK12705   33 KEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEERLVQKEEQLDAraeKLDNLENQLEEREK 112

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568959107 1320 DVKARLAQLNVQEENIRKEkqllldAQRQAALEREEATATHQHLEEAKKEHTHLLETKQQLRR 1382
Cdd:PRK12705  113 ALSARELELEELEKQLDNE------LYRVAGLTPEQARKLLLKLLDAELEEEKAQRVKKIEEE 169

DUF4670

pfam15709

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

1070-1291

2.36e-04

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 45.71 E-value: 2.36e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1070 EQQAALQRLREEAETLQKAERASLEQKSRRALEQLREQLEAEERSAQAALRaekeaekeaaLLQLREQLEGERKEAvagl 1149
Cdd:pfam15709  340 AERAEMRRLEVERKRREQEEQRRLQQEQLERAEKMREELELEQQRRFEEIR----------LRKQRLEEERQRQEE---- 405

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1150 EKKHSAELEQLCSSLEAKHQEVISSLQKKIEGAQQKEEAQLQESlgwAEQRAHQKVHQVTEYEQELSSLLRDKRQEVERE 1229
Cdd:pfam15709  406 EERKQRLQLQAAQERARQQQEEFRRKLQELQRKKQQEEAERAEA---EKQRQKELEMQLAEEQKRLMEMAEEERLEYQRQ 482

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568959107  1230 herkmdkmKEEhwqemADARERYEAEERKQRADllghltgelERLRRAHErelESMRQEQDQ 1291
Cdd:pfam15709  483 --------KQE-----AEEKARLEAEERRQKEE---------EAARLALE---EAMKQAQEQ 519

CALCOCO1

pfam07888

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...

1020-1377

2.41e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.

Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 45.66 E-value: 2.41e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1020 LLKAQLQKATAEEKEKEEETKIREEESRRLVCLRAQVQsrteafenqirtEQQAALQRLREEAETLQKAERAslEQKSRR 1099
Cdd:pfam07888   46 LLQAQEAANRQREKEKERYKRDREQWERQRRELESRVA------------ELKEELRQSREKHEELEEKYKE--LSASSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1100 ALEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQLE----GERKEAVAGLEKKHSAELEQLCSSLEAKHQEvISSL 1175
Cdd:pfam07888  112 ELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETElermKERAKKAGAQRKEEEAERKQLQAKLQQTEEE-LRSL 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1176 QKKIEG-----AQQKEEA-QLQESLGWAEQR---AHQKVHQVTEYEQELSSLlrdkrQEVEREHERKMDKMKEEhWQEMA 1246
Cdd:pfam07888  191 SKEFQElrnslAQRDTQVlQLQDTITTLTQKlttAHRKEAENEALLEELRSL-----QERLNASERKVEGLGEE-LSSMA 264

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1247 DARERYEAEERKQRADlLGHLTGEL---------ERLRRAHERE--LESMRQEQDqQLEDLRRRHRDHERKLQD------ 1309
Cdd:pfam07888  265 AQRDRTQAELHQARLQ-AAQLTLQLadaslalreGRARWAQEREtlQQSAEADKD-RIEKLSAELQRLEERLQEermere 342

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568959107  1310 -LEVELsSRTKDVKarlaqlNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLeeakKEHTHLLETK 1377
Cdd:pfam07888  343 kLEVEL-GREKDCN------RVQLSESRRELQELKASLRVAQKEKEQLQAEKQEL----LEYIRQLEQR 400

GAF

COG2203

GAF domain [Signal transduction mechanisms];

1074-1424

2.61e-04

GAF domain [Signal transduction mechanisms];

Pssm-ID: 441805 [Multi-domain] Cd Length: 712 Bit Score: 45.95 E-value: 2.61e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1074 ALQRLREEAETLQKAERASLEQKSRRALEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQLEGERKEAVAGLEKKH 1153
Cdd:COG2203   343 AIERARLYEALEAALAALLQELALLRLLLDLELTLLRLRQLLLELLLALLLLLSLLGAELLLLLLDAADLSGLLALEGLL 422

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1154 SAELEQLCSSLEAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLLRDKRQEVEREHERk 1233
Cdd:COG2203   423 LLDLLLLLLLLRRILLLRVLRRLLLGDEEGLVLLLALAELELLEILELLVLLAVILLALALLAALLLLLLLLLALLALS- 501

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1234 mdkmkEEHWQEMADARERYEAEERKQRADLLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVE 1313
Cdd:COG2203   502 -----ALAVLASLLLALLLLLLLLLLLLLLGLLAALAADLLLLAAALLEDLLILLLVLLLERELLTLVGVLLLLGLSVLL 576

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1314 LSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVE 1393
Cdd:COG2203   577 IELALALILALALLELLLVAVGDLLLLERDLLLLLVLLVRLLLELLVVTLELTVLVVLAAVEDSALLLRLALALASLVLL 656

                         330       340       350
                  ....*....|....*....|....*....|.
gi 568959107 1394 LESQVDLLQAQSQRLQKHLSSLEAEVQRKQD 1424
Cdd:COG2203   657 RALLATELDLILDSSLLLGLLLLGALLLLGG 687

DUF4670

pfam15709

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

1251-1432

2.64e-04

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 45.71 E-value: 2.64e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1251 RYEAEERKQRAD------LLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKAR 1324
Cdd:pfam15709  283 KYDAEESQVSIDgrssptQTFVVTGNMESEEERSEEDPSKALLEKREQEKASRDRLRAERAEMRRLEVERKRREQEEQRR 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1325 LAQlNVQEENIRKEKQLLLDAQRQAalerEEATATHQHLEEAKKEHTHLlETKQQLRRTIDDLRVRRVELESQVDLLQAQ 1404
Cdd:pfam15709  363 LQQ-EQLERAEKMREELELEQQRRF----EEIRLRKQRLEEERQRQEEE-ERKQRLQLQAAQERARQQQEEFRRKLQELQ 436

                          170       180
                   ....*....|....*....|....*...
gi 568959107  1405 SQRLQKHLSSLEAEVQRKQDVLKEMAAE 1432
Cdd:pfam15709  437 RKKQQEEAERAEAEKQRQKELEMQLAEE 464

smart00456

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ...

57-87

2.83e-04

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides.

Pssm-ID: 197736 [Multi-domain] Cd Length: 33 Bit Score: 39.89 E-value: 2.83e-04

                            10        20        30
                    ....*....|....*....|....*....|.
gi 568959107     57 PLPKGWKPCQNITGDLYYFNFDTGQSIWDHP 87
Cdd:smart00456    1 PLPPGWEERKDPDGRPYYYNHETKETQWEKP 31

PRK10929

putative mechanosensitive channel protein; Provisional

1064-1421

2.89e-04

putative mechanosensitive channel protein; Provisional

Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 45.82 E-value: 2.89e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1064 ENQIRTEQQAAlqrlrEEAETLQKAERASLEQKSRRALEQLREQLEAEERSAQAAlraekeaEKEAALLQ-LREQLEGER 1142
Cdd:PRK10929   25 EKQITQELEQA-----KAAKTPAQAEIVEALQSALNWLEERKGSLERAKQYQQVI-------DNFPKLSAeLRQQLNNER 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1143 KEAVAGLEKKHSAELEQlcSSLEAKHQEVISSLQkkiegAQQKEEA--QLQESLGWAEQRAHQKVHQVTEYEQELSSLlr 1220
Cdd:PRK10929   93 DEPRSVPPNMSTDALEQ--EILQVSSQLLEKSRQ-----AQQEQDRarEISDSLSQLPQQQTEARRQLNEIERRLQTL-- 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1221 DKRQEVEREHERKMDKMkeehwqemadareryEAEERKQRADLLghltgELERLRRAHERELESMR--------QEQDQQ 1292
Cdd:PRK10929  164 GTPNTPLAQAQLTALQA---------------ESAALKALVDEL-----ELAQLSANNRQELARLRselakkrsQQLDAY 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1293 LEDLR-----RRHRDHERKLQ----------DLEVELSSRTKDVKARLAQLNVQEENIrkekQLLLDAQRQAA---LERE 1354
Cdd:PRK10929  224 LQALRnqlnsQRQREAERALEstellaeqsgDLPKSIVAQFKINRELSQALNQQAQRM----DLIASQQRQAAsqtLQVR 299

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1355 EATATHQHLEEAKKEHTHLLET-------------KQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQR 1421
Cdd:PRK10929  300 QALNTLREQSQWLGVSNALGEAlraqvarlpempkPQQLDTEMAQLRVQRLRYEDLLNKQPQLRQIRQADGQPLTAEQNR 379

ARGLU

pfam15346

Arginine and glutamate-rich 1; ARGLU, arginine and glutamate-rich 1 protein family, is ...

1212-1343

3.43e-04

Arginine and glutamate-rich 1; ARGLU, arginine and glutamate-rich 1 protein family, is required for the oestrogen-dependent expression of ESR1 target genes. It functions in cooperation with MED1. The family of proteins is found in eukaryotes.

Pssm-ID: 405931 [Multi-domain] Cd Length: 151 Bit Score: 42.73 E-value: 3.43e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1212 EQELSSLLRDKRQEVEREHERKMDKMKEEHWQEMAD--ARERYEAEERKQRADllghltgELERLRRAherELESMRQEQ 1289
Cdd:pfam15346   21 AKRVEEELEKRKDEIEAEVERRVEEARKIMEKQVLEelEREREAELEEERRKE-------EEERKKRE---ELERILEEN 90

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 568959107  1290 DQQLEDLRRRHRDHERKlqdlEVELSSRTKDVKARLAQLnvQEENIRKEKQLLL 1343
Cdd:pfam15346   91 NRKIEEAQRKEAEERLA----MLEEQRRMKEERQRREKE--EEEREKREQQKIL 138

YqiK

COG2268

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

1207-1369

3.65e-04

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 45.25 E-value: 3.65e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1207 QVTEYEQE---LSSLLRDKRQEV-------EREHERKMDKMKEEHWQEMADARERYEAE-ERKQRADLlghlTGELERLR 1275
Cdd:COG2268   175 AITDLEDEnnyLDALGRRKIAEIirdariaEAEAERETEIAIAQANREAEEAELEQEREiETARIAEA----EAELAKKK 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1276 RAHERELESMRQEQDQQLEDLRrrhrdhERKLQDLE--VELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALER 1353
Cdd:COG2268   251 AEERREAETARAEAEAAYEIAE------ANAEREVQrqLEIAEREREIELQEKEAEREEAELEADVRKPAEAEKQAAEAE 324

                         170
                  ....*....|....*.
gi 568959107 1354 EEATATHQhLEEAKKE 1369
Cdd:COG2268   325 AEAEAEAI-RAKGLAE 339

PLN02939

transferase, transferring glycosyl groups

1275-1581

3.97e-04

transferase, transferring glycosyl groups

Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 45.28 E-value: 3.97e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1275 RRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENI-------RKEKQLLLDAQR 1347
Cdd:PLN02939   36 RARRRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDhnrasmqRDEAIAAIDNEQ 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1348 QAALEREEATATHQhLEEakkehthLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLK 1427
Cdd:PLN02939  116 QTNSKDGEQLSDFQ-LED-------LVGMIQNAEKNILLLNQARLQALEDLEKILTEKEALQGKINILEMRLSETDARIK 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1428 eMAAEMNAspHPE-PGLHIEDLRKSLDTNKNQEVSSSLSLSKEEIDLSMESVR-----QFLSAEGVAVRNAKEFLVRqtr 1501
Cdd:PLN02939  188 -LAAQEKI--HVEiLEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLlkddiQFLKAELIEVAETEERVFK--- 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1502 sMRRRQTALKAAQQHWRHELASAQE---------VDEDLPGTEVLGNMrknLNEETRHLDEMKSAMRKGHDLLKKKEEkl 1572
Cdd:PLN02939  262 -LEKERSLLDASLRELESKFIVAQEdvsklsplqYDCWWEKVENLQDL---LDRATNQVEKAALVLDQNQDLRDKVDK-- 335


                  ....*....
gi 568959107 1573 iqLESSLQE 1581
Cdd:PLN02939  336 --LEASLKE 342

DUF4659

pfam15558

Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins ...

1046-1350

4.29e-04

Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins in this family are typically between 427 and 674 amino acids in length. There are two completely conserved residues (D and I) that may be functionally important.

Pssm-ID: 464768 [Multi-domain] Cd Length: 374 Bit Score: 44.64 E-value: 4.29e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1046 SRR--LVCLRAQVQSRTEAFENQIRTEQQAALQRLREEAETLQKAERASLEQKSRRALEQL-REQLEAEERSAQAALRAE 1122
Cdd:pfam15558   51 ERRllLQQSQEQWQAEKEQRKARLGREERRRADRREKQVIEKESRWREQAEDQENQRQEKLeRARQEAEQRKQCQEQRLK 130

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1123 KEAEKEAALLQlREQLEGERKEAVAGlEKKHSAELEQLCSSLEAKHQEVISSLQKKIEGAQQ--KEEAQLQESLGWAEQR 1200
Cdd:pfam15558  131 EKEEELQALRE-QNSLQLQERLEEAC-HKRQLKEREEQKKVQENNLSELLNHQARKVLVDCQakAEELLRRLSLEQSLQR 208

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1201 AHQKVHQVTEyeqelssllrdKRQEVEREHERKMdkmkEEHWQEMADARERYEaEERKQRADLLGHLTGelERLRRAHER 1280
Cdd:pfam15558  209 SQENYEQLVE-----------ERHRELREKAQKE----EEQFQRAKWRAEEKE-EERQEHKEALAELAD--RKIQQARQV 270

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1281 ELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAA 1350
Cdd:pfam15558  271 AHKTVQDKAQRARELNLEREKNHHILKLKVEKEEKCHREGIKEAIKKKEQRSEQISREKEATLEEARKTA 340

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

1313-1532

4.87e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.29 E-value: 4.87e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1313 ELSSRTKDVKARLAQLNVQEENIRKEKQ---LLLDAqRQAALEREEATATHQHLEEAKKEHTHL-LETKQQL-RRTIDDL 1387
Cdd:COG4913   222 DTFEAADALVEHFDDLERAHEALEDAREqieLLEPI-RELAERYAAARERLAELEYLRAALRLWfAQRRLELlEAELEEL 300

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1388 RVRRVELESQVDLLQAQSQRLQKHLSSLEA-------------------------EVQRKQDVLKEMAAEMnasphpepG 1442
Cdd:COG4913   301 RAELARLEAELERLEARLDALREELDELEAqirgnggdrleqlereierlereleERERRRARLEALLAAL--------G 372

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1443 LHIEDLRKSLDTNKnQEVSSSLSLSKEEIDLSMESVRQFLSAEgVAVRNAKEFLVRQTRSMRRRQTALKAAQQHWRHELA 1522
Cdd:COG4913   373 LPLPASAEEFAALR-AEAAALLEALEEELEALEEALAEAEAAL-RDLRRELRELEAEIASLERRKSNIPARLLALRDALA 450

                         250
                  ....*....|.
gi 568959107 1523 SAQEVDE-DLP 1532
Cdd:COG4913   451 EALGLDEaELP 461

DUF4686

pfam15742

Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ...

1191-1589

4.95e-04

Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.

Pssm-ID: 464838 [Multi-domain] Cd Length: 384 Bit Score: 44.67 E-value: 4.95e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1191 QESLGWAEQRAHQKVHQVTeyeQELSSLLRDKRQEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRAD----LLGH 1266
Cdd:pfam15742    4 GEKLKYQQQEEVQQLRQNL---QRLQILCTSAEKELRYERGKNLDLKQHNSLLQEENIKIKAELKQAQQKLLdstkMCSS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1267 LTGELERLR-RAHERELESMRQEQD--------QQLEDLRRRHRDHERKLQDLEVELSSrtkdvkarLAQLNVQEENIRK 1337
Cdd:pfam15742   81 LTAEWKHCQqKIRELELEVLKQAQSiksqnslqEKLAQEKSRVADAEEKILELQQKLEH--------AHKVCLTDTCILE 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1338 EKQLlldaQRQAALEREEATATHQHLEEakkehthlletkQQLRRTIDDLRVRrvELESQVDLLQAQSQRLQKHLSSLEA 1417
Cdd:pfam15742  153 KKQL----EERIKEASENEAKLKQQYQE------------EQQKRKLLDQNVN--ELQQQVRSLQDKEAQLEMTNSQQQL 214

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1418 EVQRKQDVLKEMAAEMNASphpepglhiEDLRKSldtnkNQEVSSSLSLSKEEIDLSMESVRQFLSAEGVAVRNAKEflv 1497
Cdd:pfam15742  215 RIQQQEAQLKQLENEKRKS---------DEHLKS-----NQELSEKLSSLQQEKEALQEELQQVLKQLDVHVRKYNE--- 277

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1498 RQTrsmrRRQTALKAAQQHWRHELASAQEVDEDLpgtevlgnmrKNLNEETRHLDEMKSAMrkgHDLLKKKEEKLIQLES 1577
Cdd:pfam15742  278 KHH----HHKAKLRRAKDRLVHEVEQRDERIKQL----------ENEIGILQQQSEKEKAF---QKQVTAQNEILLLEKR 340

                          410
                   ....*....|..
gi 568959107  1578 SLQEEVSDEDTL 1589
Cdd:pfam15742  341 KLLEQLTEQEEL 352

Crescentin

pfam19220

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...

1263-1421

5.06e-04

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.

Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 44.67 E-value: 5.06e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1263 LLGHLTGELERLRRAHER--ELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKdvKARLAQLNVQEENIRKEKQ 1340
Cdd:pfam19220   32 LIEPIEAILRELPQAKSRllELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVA--RLAKLEAALREAEAAKEEL 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1341 LLLDAQRQAALEREE--ATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAE 1418
Cdd:pfam19220  110 RIELRDKTAQAEALErqLAAETEQNRALEEENKALREEAQAAEKALQRAEGELATARERLALLEQENRRLQALSEEQAAE 189


                   ...
gi 568959107  1419 VQR 1421
Cdd:pfam19220  190 LAE 192

CALCOCO1

pfam07888

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...

1255-1432

5.26e-04

Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 44.89 E-value: 5.26e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1255 EERKQRADLLghltgeleRLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDV---KARLAQLNVQ 1331
Cdd:pfam07888   38 ECLQERAELL--------QAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHeelEEKYKELSAS 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1332 EENIRKEKQLLLDA-----QRQAALEREEATATHQHLEeakkEHTHLLETKQQLRRTIDDLRvrrvELESQVDLLQAQSQ 1406
Cdd:pfam07888  110 SEELSEEKDALLAQraaheARIRELEEDIKTLTQRVLE----RETELERMKERAKKAGAQRK----EEEAERKQLQAKLQ 181

                          170       180
                   ....*....|....*....|....*.
gi 568959107  1407 RLQKHLSSLEAEVQRKQDVLKEMAAE 1432
Cdd:pfam07888  182 QTEEELRSLSKEFQELRNSLAQRDTQ 207

PRK12704

phosphodiesterase; Provisional

1072-1262

5.75e-04

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 44.77 E-value: 5.75e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1072 QAALQRLREEAETLQKAERASLEQKSRRALeqlreqLEAEERsaqaalraekeaekeaaLLQLREQLEGERKEAVAGLEK 1151
Cdd:PRK12704   30 EAKIKEAEEEAKRILEEAKKEAEAIKKEAL------LEAKEE-----------------IHKLRNEFEKELRERRNELQK 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1152 khsaeleqlcssLEAKHQEVISSLQKKIEGAQQKEEaQLQESlgwaEQRAHQKVHQVTEYEQELSSLLRDKRQEVER--- 1228
Cdd:PRK12704   87 ------------LEKRLLQKEENLDRKLELLEKREE-ELEKK----EKELEQKQQELEKKEEELEELIEEQLQELERisg 149

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 568959107 1229 ---EHERKM--DKMKEEHWQEMADARERYEaEERKQRAD 1262
Cdd:PRK12704  150 ltaEEAKEIllEKVEEEARHEAAVLIKEIE-EEAKEEAD 187

PHA03247

large tegument protein UL36; Provisional

325-740

6.14e-04

large tegument protein UL36; Provisional

Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 44.93 E-value: 6.14e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  325 PGGDKGQNTAPLPPSEEEPSLSlgSSDHALPARRNKLFLLESGPAEDLSWQGVPGEGGDVGRERWRRESPGLwmgqvSKL 404
Cdd:PHA03247 2601 PVDDRGDPRGPAPPSPLPPDTH--APDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRL-----GRA 2673

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  405 INKDTPERcKETEPAAPK---DAEASAEDSPQGPSPMPPETLASEPVPKPPLGDPANEDRQHPPGSLEPLNEDGKPSTPG 481
Cdd:PHA03247 2674 AQASSPPQ-RPRRRAARPtvgSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPG 2752

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  482 TDS------------------DNSSGGGSSLASPLGSQVLGEINNFPWDLQNPQGSVPVMGPLGPGPRDVRFCPFLVPQL 543
Cdd:PHA03247 2753 GPArparppttagppapappaAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPT 2832

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  544 SHISSVEEQSesedySEDQRFYQHILQMVKISRQLEGLGLPENMQEMPCKDVAGMVCSMANEPSRMSNKGDHKATRAPER 623
Cdd:PHA03247 2833 SAQPTAPPPP-----PGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPER 2907

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  624 DSgllawGPELLEHPLgaVSAPAGQEATQQAQCQPSGLRQGPVQPSPDTGLGAEPSKMQLLSQVLGSPLALVQAPLWGL- 702
Cdd:PHA03247 2908 PP-----QPQAPPPPQ--PQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVp 2980

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 568959107  703 --APLRGLGDAPPSALRGSQSVSLGSSADSGHLGEPTLPP 740
Cdd:PHA03247 2981 qpAPSREAPASSTPPLTGHSLSRVSSWASSLALHEETDPP 3020

COG4372

Uncharacterized protein, contains DUF3084 domain [Function unknown];

1052-1337

6.24e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];

Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 44.12 E-value: 6.24e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1052 LRAQVQSRTEAFENQI--RTEQQAALQRLREEAETLQKaERASLeQKSRRALEQLREQLEAEERSAQAALraekeAEKEA 1129
Cdd:COG4372    78 LEEELEELNEQLQAAQaeLAQAQEELESLQEEAEELQE-ELEEL-QKERQDLEQQRKQLEAQIAELQSEI-----AEREE 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1130 ALLQLREQLEGERKEAVAGLEKKHSAELEQLCSSLEAKHQEVISSLQKKIEGAQQkEEAQLQESLGWAEQRAHQKVHQVT 1209
Cdd:COG4372   151 ELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEA-EKLIESLPRELAEELLEAKDSLEA 229

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1210 EYEQELSSLLRDKRQEVEREHERKMDKMKEehwqemADARERYEAEERKQRADLLGHLTGELERLRRAHERELESMRQEQ 1289
Cdd:COG4372   230 KLGLALSALLDALELEEDKEELLEEVILKE------IEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLN 303

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 568959107 1290 DQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRK 1337
Cdd:COG4372   304 LAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLL 351

PHA02562

endonuclease subunit; Provisional

1214-1432

6.43e-04

endonuclease subunit; Provisional

Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 44.62 E-value: 6.43e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1214 ELSSLLRDKRQEVEREheRKMDKMKEEHWQEMADARERYEAEERKQRADllghltgELERLRRAHERELESMRQEQdQQL 1293
Cdd:PHA02562  167 EMDKLNKDKIRELNQQ--IQTLDMKIDHIQQQIKTYNKNIEEQRKKNGE-------NIARKQNKYDELVEEAKTIK-AEI 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1294 EDLRRRHRDHERKLQDLevelSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQrqaalereEATATHQHLEEAKKEHTHL 1373
Cdd:PHA02562  237 EELTDELLNLVMDIEDP----SAALNKLNTAAAKIKSKIEQFQKVIKMYEKGG--------VCPTCTQQISEGPDRITKI 304

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568959107 1374 LETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQ----------KHLSSLEAEVQRKQDVLKEMAAE 1432
Cdd:PHA02562  305 KDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLLelknkistnkQSLITLVDKAKKVKAAIEELQAE 373

PRK10246

exonuclease subunit SbcC; Provisional

1054-1454

7.55e-04

exonuclease subunit SbcC; Provisional

Pssm-ID: 182330 [Multi-domain] Cd Length: 1047 Bit Score: 44.41 E-value: 7.55e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1054 AQVQSRTEAF------ENQIRTEQQAALQRL----REEAETLQKAERASLEQKSRRALEQLREQLEAEERSAQAAlraek 1123
Cdd:PRK10246  216 EQVQSLTASLqvltdeEKQLLTAQQQQQQSLnwltRLDELQQEASRRQQALQQALAAEEKAQPQLAALSLAQPAR----- 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1124 eaekeaallQLREQLEgERKEAVAGLE--KKHSAELEQLCSSLEAKHQEVISSLQKKIEgAQQKEEAQL----------- 1190
Cdd:PRK10246  291 ---------QLRPHWE-RIQEQSAALAhtRQQIEEVNTRLQSTMALRARIRHHAAKQSA-ELQAQQQSLntwlaehdrfr 359

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1191 ---QESLGWAEQRAHQKV--HQVTEYEQELSSLlrdkrqeverehERKMDKMKEEHW----QEMADARERYEAEE--RKQ 1259
Cdd:PRK10246  360 qwnNELAGWRAQFSQQTSdrEQLRQWQQQLTHA------------EQKLNALPAITLtltaDEVAAALAQHAEQRplRQR 427

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1260 RADLLGHLTGELERLRRAHE--RELESMRQEQDQQLEDLRRRHRDHERKLQDLEV--ELSSRTKDVKARLAQLNVqeeni 1335
Cdd:PRK10246  428 LVALHGQIVPQQKRLAQLQVaiQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTicEQEARIKDLEAQRAQLQA----- 502

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1336 rKEKQLLLDAQRQAALEREEA---TATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHL 1412
Cdd:PRK10246  503 -GQPCPLCGSTSHPAVEAYQAlepGVNQSRLDALEKEVKKLGEEGAALRGQLDALTKQLQRDESEAQSLRQEEQALTQQW 581

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|..
gi 568959107 1413 SSLEAEVQRKQDVLKEMAAEMNASPHPEPGLHIEDLRKSLDT 1454
Cdd:PRK10246  582 QAVCASLNITLQPQDDIQPWLDAQEEHERQLRLLSQRHELQG 623

CCCAP

pfam15964

Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ...

1132-1583

7.65e-04

Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.

Pssm-ID: 435040 [Multi-domain] Cd Length: 703 Bit Score: 44.51 E-value: 7.65e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1132 LQLREQLEGERKEAVAGLEKKHSAELEQLCSSLEA--KHQE--VISSLQKKIEGAQQKEeAQLQESLGWAEQRAH-QKVH 1206
Cdd:pfam15964  225 LKLLYEAKTEVLESQVKSLRKDLAESQKTCEDLKErlKHKEslVAASTSSRVGGLCLKC-AQHEAVLAQTHTNVHmQTIE 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1207 QVTEYEQELSSLLRDKRQEVEREHERKMDKMKE-EHWQEMADareryEAEERKQRADL-LGHLTGELERLRRAHERELES 1284
Cdd:pfam15964  304 RLTKERDDLMSALVSVRSSLAEAQQRESSAYEQvKQAVQMTE-----EANFEKTKALIqCEQLKSELERQKERLEKELAS 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1285 -----------MRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKD-------VKARLAQLNVQEENIRK---EKQLLL 1343
Cdd:pfam15964  379 qqekraqekeaLRKEMKKEREELGATMLALSQNVAQLEAQVEKVTREknslvsqLEEAQKQLASQEMDVTKvcgEMRYQL 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1344 DaqrQAALEREEA--------TATHQHLE----EAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLqAQSQRlQKH 1411
Cdd:pfam15964  459 N---QTKMKKDEAekehreyrTKTGRQLEikdqEIEKLGLELSESKQRLEQAQQDAARAREECLKLTELL-GESEH-QLH 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1412 LSSLEAEvQRKQDVLKEMAAEMNASPHPEPGLhiedlrksldTNKNQEVSSSLSLSKEEIDLSMESVRQFLSAEGVAVRN 1491
Cdd:pfam15964  534 LTRLEKE-SIQQSFSNEAKAQALQAQQREQEL----------TQKMQQMEAQHDKTVNEQYSLLTSQNTFIAKLKEECCT 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1492 AKEFLVRQTRSMRRRQTALKAAQQHWRHELASAQEVDEDLPGTEVL-GNMRKNLNEETRHLDEMKSAMRKGHDLLKKKEE 1570
Cdd:pfam15964  603 LAKKLEEITQKSRSEVEQLSQEKEYLQDRLEKLQKRNEELEEQCVQhGRMHERMKQRLRQLDKHCQATAQQLVQLLSKQN 682

                          490
                   ....*....|...
gi 568959107  1571 KLIQLESSLQEEV 1583
Cdd:pfam15964  683 QLFKERQNLTEEV 695

Apolipoprotein

pfam01442

Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a ...

1052-1192

1.09e-03

Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a pair of alpha helices. This family includes: Apolipoprotein A-I. Apolipoprotein A-IV. Apolipoprotein E.

Pssm-ID: 460211 [Multi-domain] Cd Length: 175 Bit Score: 41.87 E-value: 1.09e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1052 LRAQVQSRTEAFENQIrteqQAALQRLREEAETLQKAERASLEQKsrraLEQLREQLEAEERSAQAALRAEKEaekeaal 1131
Cdd:pfam01442   49 VRAKLEPYLEELQAKL----GQNVEELRQRLEPYTEELRKRLNAD----AEELQEKLAPYGEELRERLEQNVD------- 113

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568959107  1132 lQLREQLEGERKEAVAGLEKKhsaeLEQLCSSLEAKHQEVISSLQKKIEGAQQKEEAQLQE 1192
Cdd:pfam01442  114 -ALRARLAPYAEELRQKLAER----LEELKESLAPYAEEVQAQLSQRLQELREKLEPQAED 169

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

996-1232

1.11e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.60 E-value: 1.11e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  996 QEEQDDSKSSIAEPQS--KHTQGSESLLKAQLQkataeekekeeetkireEESRRLVCLRAQVQsrteAFENQIRtEQQA 1073
Cdd:COG4942    26 EAELEQLQQEIAELEKelAALKKEEKALLKQLA-----------------ALERRIAALARRIR----ALEQELA-ALEA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1074 ALQRLREEAETLQKaeraSLEQKSRRALEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQLEGERKEAVAGLEKKh 1153
Cdd:COG4942    84 ELAELEKEIAELRA----ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRAD- 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1154 SAELEQLCSSLEAKHQEVISSLQKKIE-----GAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLLRDKRQEVER 1228
Cdd:COG4942   159 LAELAALRAELEAERAELEALLAELEEeraalEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238


                  ....
gi 568959107 1229 EHER 1232
Cdd:COG4942   239 AAER 242

PRK00409

recombination and DNA strand exchange inhibitor protein; Reviewed

1250-1483

1.16e-03

recombination and DNA strand exchange inhibitor protein; Reviewed

Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 44.05 E-value: 1.16e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1250 ERYEAEERKQRADLLghltgELERLRraheRELESMRQEQDQQLEDLRRRhrdHERKLQDLEVELSSRTKDVKARLAQln 1329
Cdd:PRK00409  523 ASLEELERELEQKAE-----EAEALL----KEAEKLKEELEEKKEKLQEE---EDKLLEEAEKEAQQAIKEAKKEADE-- 588

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1330 vqeenIRKEKQLLLDAQrQAALEREEATATHQHLEEAKKEhthlLETKQQLRRTIDDL-----RVRRVELESQVDLLQAQ 1404
Cdd:PRK00409  589 -----IIKELRQLQKGG-YASVKAHELIEARKRLNKANEK----KEKKKKKQKEKQEElkvgdEVKYLSLGQKGEVLSIP 658

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1405 SQRlqkhlsslEAEVQrkQDVLKemaaeMNasphpepgLHIEDLRKSLDTNKNQEVSSSLSLSKE-----EIDL------ 1473
Cdd:PRK00409  659 DDK--------EAIVQ--AGIMK-----MK--------VPLSDLEKIQKPKKKKKKKPKTVKPKPrtvslELDLrgmrye 715

                         250
                  ....*....|.
gi 568959107 1474 -SMESVRQFLS 1483
Cdd:PRK00409  716 eALERLDKYLD 726

PRK12705

hypothetical protein; Provisional

1047-1190

1.29e-03

hypothetical protein; Provisional

Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 43.54 E-value: 1.29e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1047 RRLVCLRAQVQSRTEAFENQ----IRTEQQAALQRLREEAETLQKAERASL---EQKSRRA--LEQLREQLEAEERSAQA 1117
Cdd:PRK12705   37 RILQEAQKEAEEKLEAALLEakelLLRERNQQRQEARREREELQREEERLVqkeEQLDARAekLDNLENQLEEREKALSA 116

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568959107 1118 alraekeaeKEAALLQLREQLEGERKEaVAGLEKKHSaeLEQLCSSLEAKHQEvisslQKKIEGAQQKEEAQL 1190
Cdd:PRK12705  117 ---------RELELEELEKQLDNELYR-VAGLTPEQA--RKLLLKLLDAELEE-----EKAQRVKKIEEEADL 172

FliJ

COG2882

Flagellar biosynthesis chaperone FliJ [Cell motility];

1131-1235

1.41e-03

Flagellar biosynthesis chaperone FliJ [Cell motility];

Pssm-ID: 442129 [Multi-domain] Cd Length: 142 Bit Score: 41.04 E-value: 1.41e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1131 LLQLREQLEGERKEAVAGLEKKHSAELEQLcSSLEAKHQEVISSLQKKIEGA-------------QQKEEA--QLQESLG 1195
Cdd:COG2882    10 LLDLAEKEEDEAARELGQAQQALEQAEEQL-EQLEQYREEYEQRLQQKLQQGlsaaqlrnyqqfiARLDEAieQQQQQVA 88

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 568959107 1196 WAEQRAHQKVHQVTEYEQELSSL--LRDKRQEVEREHERKMD 1235
Cdd:COG2882    89 QAEQQVEQARQAWLEARQERKALekLKERRREEERQEENRRE 130

CusB_dom_1

pfam00529

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...

1072-1228

1.45e-03

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.

Pssm-ID: 425733 [Multi-domain] Cd Length: 322 Bit Score: 42.80 E-value: 1.45e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1072 QAALQRLREEAETLQ-KAERASLEQKSRRALEQLREQLEAEERSAQAALRAEKEAekeaaLLQLREQLEGER-KEAVAGL 1149
Cdd:pfam00529   64 EAQLAKAQAQVARLQaELDRLQALESELAISRQDYDGATAQLRAAQAAVKAAQAQ-----LAQAQIDLARRRvLAPIGGI 138

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568959107  1150 EKKHSAELEQLCSSLEAKHQEVISSLQKkiegAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLLRDKRQEVER 1228
Cdd:pfam00529  139 SRESLVTAGALVAQAQANLLATVAQLDQ----IYVQITQSAAENQAEVRSELSGAQLQIAEAEAELKLAKLDLERTEIR 213

YqiK

COG2268

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

1053-1191

1.64e-03

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 42.94 E-value: 1.64e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107 1053 RAQVQSRTEAFENQIRTE---QQAALQRLREEAETLQKAERASLEQ-KSRRALEQLREQLEAEERSAQAALRAEKEAEKE 1128
Cdd:COG2268   194 IAEIIRDARIAEAEAEREteiAIAQANREAEEAELEQEREIETARIaEAEAELAKKKAEERREAETARAEAEAAYEIAEA 273

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568959107 1129 AALLQLREQLEGERKEAVAGLEKKhSAELEQlcssleakhQEVISSLQKKIEG----AQQKEEAQLQ 1191
Cdd:COG2268   274 NAEREVQRQLEIAEREREIELQEK-EAEREE---------AELEADVRKPAEAekqaAEAEAEAEAE 330

Apolipoprotein

pfam01442

Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a ...

1133-1325

1.94e-03

Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a pair of alpha helices. This family includes: Apolipoprotein A-I. Apolipoprotein A-IV. Apolipoprotein E.

Pssm-ID: 460211 [Multi-domain] Cd Length: 175 Bit Score: 41.10 E-value: 1.94e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1133 QLREQLEGERKEAVAGLEKkhsaELEQLCSSLEAKHQEVISSLQKKIEGAQQKEEAQLQEslgwaeqrahqkvhqvteYE 1212
Cdd:pfam01442   15 ELQEQLGPVAQELVDRLEK----ETEALRERLQKDLEEVRAKLEPYLEELQAKLGQNVEE------------------LR 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568959107  1213 QELSSLLRDKRQEVEREHERKMDKMKeehwQEMADARERYEAEERKQRAdllgHLTGELERLRRAHERELESMRQEQDQQ 1292
Cdd:pfam01442   73 QRLEPYTEELRKRLNADAEELQEKLA----PYGEELRERLEQNVDALRA----RLAPYAEELRQKLAERLEELKESLAPY 144

                          170       180       190
                   ....*....|....*....|....*....|...
gi 568959107  1293 LEDLRRRHRDHerkLQDLEVELSSRTKDVKARL 1325
Cdd:pfam01442  145 AEEVQAQLSQR---LQELREKLEPQAEDLREKL 174

Smc