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Conserved domains on  [gi|568916052|ref|XP_006499110|]
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excitatory amino acid transporter 2 isoform X2 [Mus musculus]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10448728)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SDF pfam00375
Sodium:dicarboxylate symporter family;
46-495 3.06e-123

Sodium:dicarboxylate symporter family;


:

Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 367.62  E-value: 3.06e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052   46 LLSLTVFGVILGAVCGGLLrlaspihPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAMVYY 124
Cdd:pfam00375   1 LLLQILIALVLGILIGLFF-------PELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYF 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052  125 MSTTIIAAVLGVILVLAIHPGNPKLKKQLGPgkKNDEVSSLDAFLDLIRNLFPENLVQACFQQiqtvtkkvlvappseea 204
Cdd:pfam00375  74 LVTTAIAALIGLLVANVFQPGSGLALIAASL--KEAKAAEAPSLLDFILNIIPSNIFEALAEG----------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052  205 nttkavismlnetmneapeetkivikkglefkdgmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIM 284
Cdd:pfam00375 135 -----------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVM 179

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052  285 WYSPLGIACLICgKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSA 364
Cdd:pfam00375 180 KLAPIGVFALIA-NTVGTYGLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSA 257

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052  365 GTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSA 444
Cdd:pfam00375 258 ATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGG 337

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568916052  445 GLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL 495
Cdd:pfam00375 338 GLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
 
Name Accession Description Interval E-value
SDF pfam00375
Sodium:dicarboxylate symporter family;
46-495 3.06e-123

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 367.62  E-value: 3.06e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052   46 LLSLTVFGVILGAVCGGLLrlaspihPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAMVYY 124
Cdd:pfam00375   1 LLLQILIALVLGILIGLFF-------PELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYF 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052  125 MSTTIIAAVLGVILVLAIHPGNPKLKKQLGPgkKNDEVSSLDAFLDLIRNLFPENLVQACFQQiqtvtkkvlvappseea 204
Cdd:pfam00375  74 LVTTAIAALIGLLVANVFQPGSGLALIAASL--KEAKAAEAPSLLDFILNIIPSNIFEALAEG----------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052  205 nttkavismlnetmneapeetkivikkglefkdgmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIM 284
Cdd:pfam00375 135 -----------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVM 179

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052  285 WYSPLGIACLICgKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSA 364
Cdd:pfam00375 180 KLAPIGVFALIA-NTVGTYGLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSA 257

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052  365 GTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSA 444
Cdd:pfam00375 258 ATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGG 337

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568916052  445 GLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL 495
Cdd:pfam00375 338 GLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
43-492 3.74e-123

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 367.90  E-value: 3.74e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052  43 KNLLLSLTVFGVILGAVCGGLLrlaspiHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAM 121
Cdd:COG1301    2 KLSLTLQILIALVLGILLGLLL------PELVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 122 VYYMSTTIIAAVLGVILVLAIHPGNPkLKKQLGPGKKNDEVSSLDaFLDLIRNLFPENLVQAcfqqiqtvtkkvlvapps 201
Cdd:COG1301   76 LYFLVTTTIALVIGLVVANLFQPGAG-LNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA------------------ 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 202 eeanttkavismlnetmneapeetkivikkgleFKDGmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVI 281
Cdd:COG1301  136 ---------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVG 181

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 282 MIMWYSPLGIACLIcGKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTA 361
Cdd:COG1301  182 WVMKLAPIGVFALI-AATVAKYGLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTS 259

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 362 SSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASI 441
Cdd:COG1301  260 SSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGV 339

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|.
gi 568916052 442 PSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIV 492
Cdd:COG1301  340 PGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVV 390
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 43-502 2.16e-40

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 151.59  E-value: 2.16e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052  43 KNLLLSLTvFGVILGAVCGGLLRLaspIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAM 121
Cdd:PRK01663   3 KPLYKSLY-FQVLVAIIIGILLGH---FYPELGAQMKPLGDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGRVGGKAL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 122 VYYMSTTIIAAVLGVILVLAIHPGNpklkkqlgpgKKNDEVSSLDAfldlirnlfpenlvqacfQQIQTVTKKvlvappS 201
Cdd:PRK01663  79 LYFEIVSTIALIIGLIVVNVVQPGA----------GMNIDPATLDA------------------KAVAQYAAQ------A 124

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 202 EEANTTKAVISMLNETMNEApeetkivikkgleFKDGmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVI 281
Cdd:PRK01663 125 HEQGTVDFLMDIIPTTVVGA-------------FASG-DILQVLLFAVLFGFALARLGEKGKPVFDFIESLSHVLFGIVN 190

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 282 MIMWYSPLG----IACLIcGKIiAIKDLevvaRQLGMYMITVIVGLIIhggiFLPLIYFVVTRKNPFSFFAgiFQAWITA 357
Cdd:PRK01663 191 MIMKLAPIGafgaMAFTI-GKY-GVGSL----VQLGQLIGCFYITCIL----FVFVVLGAIARLTGFSIFK--FIRYIKE 258

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 358 -----LGTASSAGTLPVTFRCLEdNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTAT 432
Cdd:PRK01663 259 ellivLGTSSSESALPRMMEKME-KLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLL 337

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568916052 433 LASIGAASIPSAGLVTMLLILTAVG-LPTEDISLLVAVDWLLDRMRTSVNVVGDSFgAGIVYHLSKSELDT 502
Cdd:PRK01663 338 LTSKGAAGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTNLIGNGV-ATVVVAKWEKELDR 407
 
Name Accession Description Interval E-value
SDF pfam00375
Sodium:dicarboxylate symporter family;
46-495 3.06e-123

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 367.62  E-value: 3.06e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052   46 LLSLTVFGVILGAVCGGLLrlaspihPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAMVYY 124
Cdd:pfam00375   1 LLLQILIALVLGILIGLFF-------PELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYF 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052  125 MSTTIIAAVLGVILVLAIHPGNPKLKKQLGPgkKNDEVSSLDAFLDLIRNLFPENLVQACFQQiqtvtkkvlvappseea 204
Cdd:pfam00375  74 LVTTAIAALIGLLVANVFQPGSGLALIAASL--KEAKAAEAPSLLDFILNIIPSNIFEALAEG----------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052  205 nttkavismlnetmneapeetkivikkglefkdgmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIM 284
Cdd:pfam00375 135 -----------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVM 179

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052  285 WYSPLGIACLICgKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSA 364
Cdd:pfam00375 180 KLAPIGVFALIA-NTVGTYGLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSA 257

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052  365 GTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSA 444
Cdd:pfam00375 258 ATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGG 337

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568916052  445 GLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL 495
Cdd:pfam00375 338 GLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
43-492 3.74e-123

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 367.90  E-value: 3.74e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052  43 KNLLLSLTVFGVILGAVCGGLLrlaspiHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAM 121
Cdd:COG1301    2 KLSLTLQILIALVLGILLGLLL------PELVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 122 VYYMSTTIIAAVLGVILVLAIHPGNPkLKKQLGPGKKNDEVSSLDaFLDLIRNLFPENLVQAcfqqiqtvtkkvlvapps 201
Cdd:COG1301   76 LYFLVTTTIALVIGLVVANLFQPGAG-LNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA------------------ 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 202 eeanttkavismlnetmneapeetkivikkgleFKDGmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVI 281
Cdd:COG1301  136 ---------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVG 181

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 282 MIMWYSPLGIACLIcGKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTA 361
Cdd:COG1301  182 WVMKLAPIGVFALI-AATVAKYGLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTS 259

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 362 SSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASI 441
Cdd:COG1301  260 SSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGV 339

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|.
gi 568916052 442 PSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIV 492
Cdd:COG1301  340 PGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVV 390
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 43-502 2.16e-40

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 151.59  E-value: 2.16e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052  43 KNLLLSLTvFGVILGAVCGGLLRLaspIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAM 121
Cdd:PRK01663   3 KPLYKSLY-FQVLVAIIIGILLGH---FYPELGAQMKPLGDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGRVGGKAL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 122 VYYMSTTIIAAVLGVILVLAIHPGNpklkkqlgpgKKNDEVSSLDAfldlirnlfpenlvqacfQQIQTVTKKvlvappS 201
Cdd:PRK01663  79 LYFEIVSTIALIIGLIVVNVVQPGA----------GMNIDPATLDA------------------KAVAQYAAQ------A 124

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 202 EEANTTKAVISMLNETMNEApeetkivikkgleFKDGmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVI 281
Cdd:PRK01663 125 HEQGTVDFLMDIIPTTVVGA-------------FASG-DILQVLLFAVLFGFALARLGEKGKPVFDFIESLSHVLFGIVN 190

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 282 MIMWYSPLG----IACLIcGKIiAIKDLevvaRQLGMYMITVIVGLIIhggiFLPLIYFVVTRKNPFSFFAgiFQAWITA 357
Cdd:PRK01663 191 MIMKLAPIGafgaMAFTI-GKY-GVGSL----VQLGQLIGCFYITCIL----FVFVVLGAIARLTGFSIFK--FIRYIKE 258

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 358 -----LGTASSAGTLPVTFRCLEdNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTAT 432
Cdd:PRK01663 259 ellivLGTSSSESALPRMMEKME-KLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLL 337

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568916052 433 LASIGAASIPSAGLVTMLLILTAVG-LPTEDISLLVAVDWLLDRMRTSVNVVGDSFgAGIVYHLSKSELDT 502
Cdd:PRK01663 338 LTSKGAAGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTNLIGNGV-ATVVVAKWEKELDR 407
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
 43-486 1.85e-39

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 149.53  E-value: 1.85e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052  43 KNLLLSLT---VFGVILGAVCGGLLRLASPIHPDVVMLIAFP-GDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLG 117
Cdd:PRK11283   2 KNIKFSLAwqiLIALVLGILLGAYLHYHSDSRDWLVSNLLSPaGDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 118 TRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGP------GKKNDEVSSLD-AFLDLIRNLFPENLVQAcfqqiqt 190
Cdd:PRK11283  82 AKTIIYFEVITTVAIILGITLANVFQPGAGIDMSQLATvdiskyQSTTEEVQSHShGLMGTILSLIPTNIFAS------- 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 191 vtkkvlvappseeanttkavismlnetmneapeetkivIKKGlefkdgmNVLGLIGFFIAFGIAMGKMGEQAKL-MVEFF 269
Cdd:PRK11283 155 --------------------------------------MAKG-------EMLPIIFFSVLFGLGLSSLPATHREpLVTVF 189

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 270 NILNEIVMKLVIMIMWYSPLGIACLIcgkiiaikdlEVVARQLGMYMITVIVGLII--HGGI--FLPLIYFVVTRKNPFS 345
Cdd:PRK11283 190 RSVSETMFKVTHMVMRYAPVGVFALI----------AVTVANFGFASLWPLAKLVLlvYFAIlfFALVVLGIVARLCGLS 259

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 346 FFAGIF---QAWITALGTASSAGTLPVTFRCLEdNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGG 422
Cdd:PRK11283 260 IWILIRilkDELILAYSTASSETVLPRIIEKME-AYGAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIW 338

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568916052 423 QIVTVSLTATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDS 486
Cdd:PRK11283 339 QEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNA 402
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
 51-485 9.28e-36

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 138.65  E-value: 9.28e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052  51 VFGVILGAVCGGLLrlaspihPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAMVYYMSTTI 129
Cdd:PRK13027  13 VIALVLGVALGAFF-------PHFAESLKPLGDGFIKLIKMLIGPIVFCVVVSGIAGAgDLKKVGRVGLKAVIYFEVMTT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 130 IAAVLGVILVLAIHPG---NPKLKkQLGPGKKNDEVS---SLDAFLDLIRNLFPENLVQAcfqqiqtvtkkvlvappsee 203
Cdd:PRK13027  86 IALVIGLVLAYLTGPGvgmNIDLR-SLDAASLAGYAKnaqSLKGTAGFLLKLIPTTAVDA-------------------- 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 204 anttkavismlnetmneapeetkivikkgleFKDGmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMI 283
Cdd:PRK13027 145 -------------------------------FAKG-DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSHVLFRIMGFI 192

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 284 MWYSPLGIACLIC---GKIiAIKDLevvaRQLGMYMITVIVGLIIhggiFLPLIYFVVTRKNPFSFFAGI---FQAWITA 357
Cdd:PRK13027 193 IKLAPLGVLGAIAfttGKY-GVGSL----KQLGMLVAVFYLTCFV----FVVVVLGAVMRLAGFSVFKLIrylREELLIV 263

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 358 LGTASSAGTLPVTFRCLEdNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIG 437
Cdd:PRK13027 264 LGTASSDAVLPQVMRKLE-HMGIKDSTVGLVIPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVSLVTSKG 342

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*....
gi 568916052 438 AASIPSAGLVTMLLILTAVG-LPTEDISLLVAVDWLLDRMRTSVNVVGD 485
Cdd:PRK13027 343 AHGIPGSAIVILAATLSAIPaIPVLGLVLILPVDWFMGIARALTNLIGN 391
TcyP COG1823
L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and ...
 43-492 1.81e-26

L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and metabolism];


Pssm-ID: 441428  Cd Length: 463  Bit Score: 112.61  E-value: 1.81e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052  43 KNLLLSLTVF-GVILGAVCGGLLRLA----SPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRL 116
Cdd:COG1823   26 KHVSFSKRVFtGLGLGILFGLILQLIygagSPVIKQSIDWFNIVGNGYVRLLQMIVMPLVFVSILSAITKLkNASSLGKI 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 117 GTRAMVYYMSTTIIAAVLGVILVLAIHpgnpklkkqlgpgkkndevssLDAfldlirnlfpENLVQAcfqqiqtvtkkvl 196
Cdd:COG1823  106 SGLIIGILLGTTAIAALVGILVALLFG---------------------LTA----------EGLTQG------------- 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 197 vappseEANTTKavISMLNETMNEAPEETkiVIKKGLE------FKD--GMNVLGLIG--FFIAF-GIA----MGKMGEQ 261
Cdd:COG1823  142 ------AAETAR--GEALEERLGEVEDLS--LPQQILSfiptnpFADltGARPTSTIAvvIFAAFlGIAalglRRKKPEQ 211

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 262 AKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICgKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIyfVVTRK 341
Cdd:COG1823  212 AETFLKGIDALQAIVMRLVRLVLRLTPYGVLALMT-KVVATSDFADIL-NLGKFVVASYVALIIMFIVHLLLL--ALAGL 287

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 342 NPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTA-LYEAVAAIFIAQMNGV-IL 419
Cdd:COG1823  288 NPLTYFKKVWPVLTFAFTSRSSAGTIPLNIETQTKRLGVPEGIANFAASFGATIGQNGCAgIYPAMLAVMIAPTVGInPL 367

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568916052 420 DGGQIVTVSLTATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNvVGDSFGAGIV 492
Cdd:COG1823  368 DPSFILTLIAVVTISSFGVAGVGGGATFAALIVLSAMGLPVALAGLLISIEPLIDMGRTALN-VSGSMTAGTV 439
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
 240-486 1.21e-14

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 75.09  E-value: 1.21e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 240 NVLGLIGFFIAFGIAMGKMGEQAKlmvEFFNILNEIVMKLVIMIMWYSPLGIACLICgKIIAIKDLEVVArQLGMYMITV 319
Cdd:PRK14695  60 NYIGILSWAVIFGIAMREASKNSK---ELLKTIADVTSKIVEWIINLAPFGILGLVF-KTISDKGVGSLA-NYGILLVLL 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 320 IVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQ-AWITALGTASSAGTLPVTFRCLEDnLGIDKRVTRFVLPVGATINMD 398
Cdd:PRK14695 135 VTTMLFVAPVVNPLIAFFFMRRNPYPLVWNCLRvSGVTAFFTRSSATNIPVNMKLCHD-LGLNPDTYSVSIPLGSTINMA 213

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 399 GTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRT 478
Cdd:PRK14695 214 GVAITINLLTLVTVNTLGIPVDFATAFVLSVVAAISACGASGIAGGSLLLIPVACSLFGISNDIAIQIVGVGFVIGVIQD 293


                 ....*...
gi 568916052 479 SVNVVGDS 486
Cdd:PRK14695 294 SCETALNS 301
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
 240-458 6.83e-12

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 67.58  E-value: 6.83e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 240 NVLGLIGFFIAFGIAMGKMGEQAKlmvEFFNILNEIVMKLVIMIMWYSPLGIACLICGkIIAIKDLEVVAR--QLGMYMI 317
Cdd:PRK13628 146 NYIGILAWAIGLGLALRHASDTTK---NVVNDLSEAVSQIVKWVIRFAPIGIFGLVAS-TLAETGFSALAGyaQLLAVLV 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 318 T--VIVGLIIHggiflPLIYFVVTRKNPFSF-FAGIFQAWITALGTASSAGTLPVTFRCLEDnLGIDKRVTRFVLPVGAT 394
Cdd:PRK13628 222 GcmLFVALVVN-----PLIVFWKIRRNPYPLvFTCLRESGVTAFFTRSSAANIPVNMALCEK-LGLDEDTYSVSIPLGAT 295

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568916052 395 INMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSAGLvtmLLILTAVGL 458
Cdd:PRK13628 296 INMAGAAITITVLTLAAVHTLGIPVDLPTALLLSVVAAISACGASGVAGGSL---LLIPLACSL 356
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
240-458 2.16e-10

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 62.88  E-value: 2.16e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 240 NVLGLIGFFIAFGIAMGKMGEQAKLMvefFNILNEIVMKLVIMIMWYSPLGIACLICGkIIAIKDLEVvarqLGMY--MI 317
Cdd:COG3633  145 NYIGILAWAIGLGLALRHASDTTKTV---LSDLSDAVSKIVRWVIRFAPLGIFGLVAS-TVATTGFSA----LLGYahLL 216

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568916052 318 TVIVG------LIIHggiflPLIYFVVTRKNPFSF-FAGIFQAWITALGTASSAGTLPVTFRCLEDnLGIDKRVTRFVLP 390
Cdd:COG3633  217 AVLVGcmlfvaLVVN-----PLIVFLKIRRNPYPLvFTCLRESGITAFFTRSSAANIPVNMALCEK-LGLDEDTYSVSIP 290

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568916052 391 VGATINMDGtalyeavAAIFIAQMN-------GVILDGGQIVTVSLTATLASIGAASIPSAGLvtmLLILTAVGL 458
Cdd:COG3633  291 LGATINMAG-------AAITITVLTlaavhtlGIEVDLPTALLLSVVAAVSACGASGVAGGSL---LLIPLACSL 355
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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