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Conserved domains on  [gi|568910577|ref|XP_006496772|]
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protoporphyrinogen oxidase isoform X3 [Mus musculus]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11440906)

NAD(P)/FAD-dependent oxidoreductase such as polyamine oxidase (PAO), flavin-containing monoamine oxidases (MAOs), D-amino acid dehydrogenase, and linoleic acid isomerase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 3-390 1.66e-58

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


:

Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 196.59  E-value: 1.66e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577   3 RTVIVLGGGISGLAASYHLIRgpSPPKVILVEGSKRLGGWIRSIRgSDGAIFELG------------------------- 57
Cdd:COG1232    2 KRVAVIGGGIAGLTAAYRLAK--AGHEVTVLEASDRVGGLIRTVE-VDGFRIDRGphsfltrdpevlellrelglgdelv 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  58 ------------------PRGIRPA---GALGARTLLLVA--------------SLA---------------MDSLCRGV 87
Cdd:COG1232   79 wpntrksyiyyggklhplPQGPLALlrsPLLSLAGKLRALlellaprrppgedeSLAefvrrrfgrevyerlVEPLLEGV 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  88 FAGNSRELSIRSCFPSLFQAEQTHRSillglllgagqspqpdssLIRQARAERWSQ------WSLRGGLEVLPQALHNHL 161
Cdd:COG1232  159 YAGDPDELSADWAFPRLKRLELEHGS------------------LIKGALALRKGAkagevfGYLRGGLGTLVEALAEAL 220

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577 162 asKGVTVLSGQPVCGLSLQpEGRWKVSLGD-SSLEADHIISAIPASELSKLLPAEAAPLARILSTIKAVSVAVVNLQYRG 240
Cdd:COG1232  221 --EAGEIRLGTRVTAIERE-GGGWRVTTSDgETIEADAVVSATPAPALARLLAPLPPEVAAALAGIPYASVAVVALGFDR 297

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577 241 ACL-PVQGFGHLVPSSEDPTVLGIVYDSVAFPEQDGNPPSLrVTVMLGGywlqklkaAGH----QLSPELFQQQAQEAAA 315
Cdd:COG1232  298 PDLpPPDGFGWLVPRDEGVPILAVTFSSNKWPHRAPDGKVL-LRLEVGG--------AGDpelwQLSDEELVALALADLR 368

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568910577 316 TQLGLKEPPSHCLVHLHKNCIPQYTIGHWQKLDSAMQFLtaQRLP-LTLAGASYEGVAVNDCIESGRQAAVAVLGT 390
Cdd:COG1232  369 KLLGIDAEPVDTRVVRWPKAYPQYTVGHLERVAAIREAL--AALPgLYLAGRAYDGVGLPDCIRSGREAAERILAE 442
 
Name Accession Description Interval E-value
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 3-390 1.66e-58

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 196.59  E-value: 1.66e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577   3 RTVIVLGGGISGLAASYHLIRgpSPPKVILVEGSKRLGGWIRSIRgSDGAIFELG------------------------- 57
Cdd:COG1232    2 KRVAVIGGGIAGLTAAYRLAK--AGHEVTVLEASDRVGGLIRTVE-VDGFRIDRGphsfltrdpevlellrelglgdelv 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  58 ------------------PRGIRPA---GALGARTLLLVA--------------SLA---------------MDSLCRGV 87
Cdd:COG1232   79 wpntrksyiyyggklhplPQGPLALlrsPLLSLAGKLRALlellaprrppgedeSLAefvrrrfgrevyerlVEPLLEGV 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  88 FAGNSRELSIRSCFPSLFQAEQTHRSillglllgagqspqpdssLIRQARAERWSQ------WSLRGGLEVLPQALHNHL 161
Cdd:COG1232  159 YAGDPDELSADWAFPRLKRLELEHGS------------------LIKGALALRKGAkagevfGYLRGGLGTLVEALAEAL 220

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577 162 asKGVTVLSGQPVCGLSLQpEGRWKVSLGD-SSLEADHIISAIPASELSKLLPAEAAPLARILSTIKAVSVAVVNLQYRG 240
Cdd:COG1232  221 --EAGEIRLGTRVTAIERE-GGGWRVTTSDgETIEADAVVSATPAPALARLLAPLPPEVAAALAGIPYASVAVVALGFDR 297

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577 241 ACL-PVQGFGHLVPSSEDPTVLGIVYDSVAFPEQDGNPPSLrVTVMLGGywlqklkaAGH----QLSPELFQQQAQEAAA 315
Cdd:COG1232  298 PDLpPPDGFGWLVPRDEGVPILAVTFSSNKWPHRAPDGKVL-LRLEVGG--------AGDpelwQLSDEELVALALADLR 368

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568910577 316 TQLGLKEPPSHCLVHLHKNCIPQYTIGHWQKLDSAMQFLtaQRLP-LTLAGASYEGVAVNDCIESGRQAAVAVLGT 390
Cdd:COG1232  369 KLLGIDAEPVDTRVVRWPKAYPQYTVGHLERVAAIREAL--AALPgLYLAGRAYDGVGLPDCIRSGREAAERILAE 442
proto_IX_ox TIGR00562
protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a ...
 3-388 1.89e-51

protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a precursor of heme and chlorophyll. Bacillus subtilis HemY also has coproporphyrinogen III to coproporphyrin III oxidase activity in a heterologous expression system, although the role for this activity in vivo is unclear. This protein is a flavoprotein and has a beta-alpha-beta dinucleotide binding motif near the amino end. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 213540 [Multi-domain]  Cd Length: 462  Bit Score: 178.49  E-value: 1.89e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577    3 RTVIVLGGGISGLAASYHL--IRGPSPPKVILVEGSKRLGGWIRSiRGSDGAIFELGPRGIR------------------ 62
Cdd:TIGR00562   3 KHVVIIGGGISGLCAAYYLekEIPELPVELTLVEASDRVGGKIQT-VKEDGYLIERGPDSFLerkksapdlvkdlglehv 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577   63 -------------PAGAL--------------------GARTLLL------------------------VASLAMDSLCR 85
Cdd:TIGR00562  82 lvsdatgqryvlvNRGKLmpvptkiapfvktglfslggKLRAGMDfirpaspgkdesveefvrrrfgdeVVENLIEPLLS 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577   86 GVFAGNSRELSIRSCFPSLFQAEQTHRSILLGLLLGAgQSPQpDSSLIRQARAERWSQWSLRGGLEVLPQALHNHLasKG 165
Cdd:TIGR00562 162 GIYAGDPSKLSLKSTFPKFYQTEQKHGSLILGMKKTR-NLPQ-GSGLQLTAKKQGQDFQTLATGLETLPEEIEKRL--KL 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  166 VTVLSGQPVCGLSLQPEGRWKVSLGDSSLEADHIISAIPASELSKLLPAEAAPLARILSTIKAVSVAVVNLQYRGACL-- 243
Cdd:TIGR00562 238 TKVYKGTKVTKLSHRGSNYTLELDNGVTVETDSVVVTAPHKAAAGLLSELSNSASSHLDKIHSPPVANVNLGFPEGSVdg 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  244 PVQGFGHLVPSSEDPTVLGIVYDSVAFPEQdgNPP-SLRVTVMLGGywlqKLKAAGHQLSPELFQQQAQEAAATQLGLKE 322
Cdd:TIGR00562 318 ELEGFGFLISRSSKFAILGCIFTSKLFPNR--APPgKTLLTAYIGG----ATDESIVDLSENEIINIVLRDLKKVLNINN 391

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568910577  323 PPSHCLVHLHKNCIPQYTIGHWQKLDSAMQFLTAQRLPLTLAGASYEGVAVNDCIESGRQAAVAVL 388
Cdd:TIGR00562 392 EPEMLCVTRWHRAIPQYHVGHDQRLKEARELLESAYPGVFLTGNSFEGVGIPDCIDQGKAAASDVL 457
PRK11883 PRK11883
protoporphyrinogen oxidase; Reviewed
 3-389 5.63e-35

protoporphyrinogen oxidase; Reviewed


Pssm-ID: 237009 [Multi-domain]  Cd Length: 451  Bit Score: 133.82  E-value: 5.63e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577   3 RTVIVLGGGISGLAASYHLIRGPSPPKVILVEGSKRLGGWIRSIRgSDGAIFELGPRG---------------------I 61
Cdd:PRK11883   1 KKVAIIGGGITGLSAAYRLHKKGPDADITLLEASDRLGGKIQTVR-KDGFPIELGPESflarkpsapalvkelgledelV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  62 RPAGA------------LGARTL---------LLVASL---------AMDS----------------------------- 82
Cdd:PRK11883  80 ANTTGqsyiyvngklhpIPPGTVmgiptsiapFLFAGLvspigklraAADLrpprwkpgqdqsvgaffrrrfgdevvenl 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  83 ---LCRGVFAGNSRELSIRSCFPSLFQAEQTHRSILLGLLLGAGQSPQPDSSLIRQaraerwsqwsLRGGLEVLPQALHN 159
Cdd:PRK11883 160 iepLLSGIYAGDIDTLSLRATFPQLAQAEDKYGSLLRGMRKALPKEKKKTKGVFGT----------LKGGLQSLIEALEE 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577 160 HLASKgvTVLSGQPVCGLSLQPEGrWKVSL-GDSSLEADHIISAIPASELSKLLPAEAAplARILSTIKAVSVAVVNLQY 238
Cdd:PRK11883 230 KLPAG--TIHKGTPVTKIDKSGDG-YEIVLsNGGEIEADAVIVAVPHPVLPSLFVAPPA--FALFKTIPSTSVATVALAF 304

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577 239 RGACLPV-QGFGHLVPSSEDPTVLGIVYDSVAFPEQdgNPPS---LRVTVmlgGYWLQKLKAAGHQlspELFQQQAQEAA 314
Cdd:PRK11883 305 PESATNLpDGTGFLVARNSDYTITACTWTSKKWPHT--TPEGkvlLRLYV---GRPGDEAVVDATD---EELVAFVLADL 376

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568910577 315 ATQLGLKEPPSHCLVHLHKNCIPQYTIGHWQKLDSAMQFLtaQRLP-LTLAGASYEGVAVNDCIESGRQAAVAVLG 389
Cdd:PRK11883 377 SKVMGITGDPEFTIVQRWKEAMPQYGVGHIERVAELRAGL--PHYPgLYVAGASFEGVGLPDCIAQAKRAAARLLA 450
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 12-388 1.25e-29

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 119.13  E-value: 1.25e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577   12 ISGLAASYHLIRgpSPPKVILVEGSKRLGGWIRSIRgSDGAIFELGPRGIRPAGA--------LGARTLLLVASLAMDsl 83
Cdd:pfam01593   1 LAGLAAARELLR--AGHDVTVLEARDRVGGRIRTVR-DDGFLIELGAMWFHGAQPpllallkeLGLEDRLVLPDPAPF-- 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577   84 CRGVFAGNSRELSIRSCFPSLFQA----------EQTHRSILLGLLLGAGQSPQPDS-----SLIRQAR-----AERW-- 141
Cdd:pfam01593  76 YTVLFAGGRRYPGDFRRVPAGWEGllefgrllsiPEKLRLGLAALASDALDEFDLDDfslaeSLLFLGRrgpgdVEVWdr 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  142 -----------------------------------------SQWSLRGGLEVLPQALHNHLAskGVTVLSGQPVCGLSLQ 180
Cdd:pfam01593 156 lidpelfaalpfasgafagdpselsaglalpllwallgeggSLLLPRGGLGALPDALAAQLL--GGDVRLNTRVRSIDRE 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  181 PEGRWKVSLGDSSLEADHIISAIPASELSKL-----LPAEAAPLARILstiKAVSVAVVNLQYRGACLPVQgfGHLVPSS 255
Cdd:pfam01593 234 GDGVTVTLTDGEVIEADAVIVTVPLGVLKRIlftppLPPEKARAIRNL---GYGPVNKVHLEFDRKFWPDL--GLLGLLS 308

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  256 EDPTVLGIVYDSVAFPEQDGNPPSLRVTVMLG-GYWLQKLKAaghqLSPELFQQQAQEAAATQLG--LKEPPSHCLVHLH 332
Cdd:pfam01593 309 ELLTGLGTAFSWLTFPNRAPPGKGLLLLVYVGpGDRARELEG----LSDEELLQAVLRDLRKLFGeeAPEPLRVLVSDWH 384

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568910577  333 KNCIP-------QYTIGHWQKLDSAMQFLTaqrlPLTLAGAS----YEGVaVNDCIESGRQAAVAVL 388
Cdd:pfam01593 385 TDPWPrgsyslpQYGPGHDDYRPLARTPDP----GLFFAGEHtstgYPGT-VEGAIESGRRAARAVL 446
 
Name Accession Description Interval E-value
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 3-390 1.66e-58

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 196.59  E-value: 1.66e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577   3 RTVIVLGGGISGLAASYHLIRgpSPPKVILVEGSKRLGGWIRSIRgSDGAIFELG------------------------- 57
Cdd:COG1232    2 KRVAVIGGGIAGLTAAYRLAK--AGHEVTVLEASDRVGGLIRTVE-VDGFRIDRGphsfltrdpevlellrelglgdelv 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  58 ------------------PRGIRPA---GALGARTLLLVA--------------SLA---------------MDSLCRGV 87
Cdd:COG1232   79 wpntrksyiyyggklhplPQGPLALlrsPLLSLAGKLRALlellaprrppgedeSLAefvrrrfgrevyerlVEPLLEGV 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  88 FAGNSRELSIRSCFPSLFQAEQTHRSillglllgagqspqpdssLIRQARAERWSQ------WSLRGGLEVLPQALHNHL 161
Cdd:COG1232  159 YAGDPDELSADWAFPRLKRLELEHGS------------------LIKGALALRKGAkagevfGYLRGGLGTLVEALAEAL 220

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577 162 asKGVTVLSGQPVCGLSLQpEGRWKVSLGD-SSLEADHIISAIPASELSKLLPAEAAPLARILSTIKAVSVAVVNLQYRG 240
Cdd:COG1232  221 --EAGEIRLGTRVTAIERE-GGGWRVTTSDgETIEADAVVSATPAPALARLLAPLPPEVAAALAGIPYASVAVVALGFDR 297

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577 241 ACL-PVQGFGHLVPSSEDPTVLGIVYDSVAFPEQDGNPPSLrVTVMLGGywlqklkaAGH----QLSPELFQQQAQEAAA 315
Cdd:COG1232  298 PDLpPPDGFGWLVPRDEGVPILAVTFSSNKWPHRAPDGKVL-LRLEVGG--------AGDpelwQLSDEELVALALADLR 368

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568910577 316 TQLGLKEPPSHCLVHLHKNCIPQYTIGHWQKLDSAMQFLtaQRLP-LTLAGASYEGVAVNDCIESGRQAAVAVLGT 390
Cdd:COG1232  369 KLLGIDAEPVDTRVVRWPKAYPQYTVGHLERVAAIREAL--AALPgLYLAGRAYDGVGLPDCIRSGREAAERILAE 442
proto_IX_ox TIGR00562
protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a ...
 3-388 1.89e-51

protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a precursor of heme and chlorophyll. Bacillus subtilis HemY also has coproporphyrinogen III to coproporphyrin III oxidase activity in a heterologous expression system, although the role for this activity in vivo is unclear. This protein is a flavoprotein and has a beta-alpha-beta dinucleotide binding motif near the amino end. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 213540 [Multi-domain]  Cd Length: 462  Bit Score: 178.49  E-value: 1.89e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577    3 RTVIVLGGGISGLAASYHL--IRGPSPPKVILVEGSKRLGGWIRSiRGSDGAIFELGPRGIR------------------ 62
Cdd:TIGR00562   3 KHVVIIGGGISGLCAAYYLekEIPELPVELTLVEASDRVGGKIQT-VKEDGYLIERGPDSFLerkksapdlvkdlglehv 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577   63 -------------PAGAL--------------------GARTLLL------------------------VASLAMDSLCR 85
Cdd:TIGR00562  82 lvsdatgqryvlvNRGKLmpvptkiapfvktglfslggKLRAGMDfirpaspgkdesveefvrrrfgdeVVENLIEPLLS 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577   86 GVFAGNSRELSIRSCFPSLFQAEQTHRSILLGLLLGAgQSPQpDSSLIRQARAERWSQWSLRGGLEVLPQALHNHLasKG 165
Cdd:TIGR00562 162 GIYAGDPSKLSLKSTFPKFYQTEQKHGSLILGMKKTR-NLPQ-GSGLQLTAKKQGQDFQTLATGLETLPEEIEKRL--KL 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  166 VTVLSGQPVCGLSLQPEGRWKVSLGDSSLEADHIISAIPASELSKLLPAEAAPLARILSTIKAVSVAVVNLQYRGACL-- 243
Cdd:TIGR00562 238 TKVYKGTKVTKLSHRGSNYTLELDNGVTVETDSVVVTAPHKAAAGLLSELSNSASSHLDKIHSPPVANVNLGFPEGSVdg 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  244 PVQGFGHLVPSSEDPTVLGIVYDSVAFPEQdgNPP-SLRVTVMLGGywlqKLKAAGHQLSPELFQQQAQEAAATQLGLKE 322
Cdd:TIGR00562 318 ELEGFGFLISRSSKFAILGCIFTSKLFPNR--APPgKTLLTAYIGG----ATDESIVDLSENEIINIVLRDLKKVLNINN 391

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568910577  323 PPSHCLVHLHKNCIPQYTIGHWQKLDSAMQFLTAQRLPLTLAGASYEGVAVNDCIESGRQAAVAVL 388
Cdd:TIGR00562 392 EPEMLCVTRWHRAIPQYHVGHDQRLKEARELLESAYPGVFLTGNSFEGVGIPDCIDQGKAAASDVL 457
PRK11883 PRK11883
protoporphyrinogen oxidase; Reviewed
 3-389 5.63e-35

protoporphyrinogen oxidase; Reviewed


Pssm-ID: 237009 [Multi-domain]  Cd Length: 451  Bit Score: 133.82  E-value: 5.63e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577   3 RTVIVLGGGISGLAASYHLIRGPSPPKVILVEGSKRLGGWIRSIRgSDGAIFELGPRG---------------------I 61
Cdd:PRK11883   1 KKVAIIGGGITGLSAAYRLHKKGPDADITLLEASDRLGGKIQTVR-KDGFPIELGPESflarkpsapalvkelgledelV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  62 RPAGA------------LGARTL---------LLVASL---------AMDS----------------------------- 82
Cdd:PRK11883  80 ANTTGqsyiyvngklhpIPPGTVmgiptsiapFLFAGLvspigklraAADLrpprwkpgqdqsvgaffrrrfgdevvenl 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  83 ---LCRGVFAGNSRELSIRSCFPSLFQAEQTHRSILLGLLLGAGQSPQPDSSLIRQaraerwsqwsLRGGLEVLPQALHN 159
Cdd:PRK11883 160 iepLLSGIYAGDIDTLSLRATFPQLAQAEDKYGSLLRGMRKALPKEKKKTKGVFGT----------LKGGLQSLIEALEE 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577 160 HLASKgvTVLSGQPVCGLSLQPEGrWKVSL-GDSSLEADHIISAIPASELSKLLPAEAAplARILSTIKAVSVAVVNLQY 238
Cdd:PRK11883 230 KLPAG--TIHKGTPVTKIDKSGDG-YEIVLsNGGEIEADAVIVAVPHPVLPSLFVAPPA--FALFKTIPSTSVATVALAF 304

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577 239 RGACLPV-QGFGHLVPSSEDPTVLGIVYDSVAFPEQdgNPPS---LRVTVmlgGYWLQKLKAAGHQlspELFQQQAQEAA 314
Cdd:PRK11883 305 PESATNLpDGTGFLVARNSDYTITACTWTSKKWPHT--TPEGkvlLRLYV---GRPGDEAVVDATD---EELVAFVLADL 376

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568910577 315 ATQLGLKEPPSHCLVHLHKNCIPQYTIGHWQKLDSAMQFLtaQRLP-LTLAGASYEGVAVNDCIESGRQAAVAVLG 389
Cdd:PRK11883 377 SKVMGITGDPEFTIVQRWKEAMPQYGVGHIERVAELRAGL--PHYPgLYVAGASFEGVGLPDCIAQAKRAAARLLA 450
PLN02576 PLN02576
protoporphyrinogen oxidase
 2-388 4.78e-30

protoporphyrinogen oxidase


Pssm-ID: 215314 [Multi-domain]  Cd Length: 496  Bit Score: 120.89  E-value: 4.78e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577   2 GRTVIVLGGGISGLAASYHLiRGPSPPKVILVEGSKRLGGWIRSIRGsDGAIFELGPR---------------GIR---- 62
Cdd:PLN02576  12 SKDVAVVGAGVSGLAAAYAL-ASKHGVNVLVTEARDRVGGNITSVSE-DGFIWEEGPNsfqpsdpeltsavdsGLRddlv 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  63 -------------------PAGALGART-----------LLLVASL----------------------------AMDSLC 84
Cdd:PLN02576  90 fpdpqapryvvwngklrplPSNPIDLPTfdllsapgkirAGLGAFGwkrppppgreesvgefvrrhlgdevferLIDPFV 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  85 RGVFAGNSRELSIRSCFPSLFQAEQTHRSILL---GLLLGAGQSPQPDSSLIRQARAERWSQWSLRGGLEVLPQALHNHL 161
Cdd:PLN02576 170 SGVYAGDPSSLSMKAAFPKLWNLEKRGGSIIGgaiKAIQEAKKNPKPEPRDPRLPKPKGQTVGSFRGGLQTLPDALAKRL 249

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577 162 ASKGVTVLSgqPVCGLSLQPEGRWKVSL----GDSSLEADHIISAIPASELSKLLPAEAAPLARILSTIKAVSVAVVNLQ 237
Cdd:PLN02576 250 GKDKVKLNW--KVLSLSKNDDGGYSLTYdtpeGKVNVTAKAVVMTAPLYVVSEMLRPKSPAAADALPEFYYPPVAAVTTS 327

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577 238 Y--------RGACLPVQGFGHLVPSSEDPTVLGIVYDSVAFPeqDGNPPSLRV-TVMLGGYWLQKLKaaghQLSPELFQQ 308
Cdd:PLN02576 328 YpkeavkreRLIDGPLEGFGQLHPRKQGVKTLGTIYSSSLFP--DRAPEGRVLlLNYIGGSRNTGIA----SASEEELVE 401

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577 309 QAQEAAATQLGL--KEPPSHCLVHLHKNCIPQYTIGHWQKLDSAMQFLTAQRLP-LTLAGASYEGVAVNDCIESGRQAAV 385
Cdd:PLN02576 402 AVDRDLRKLLLKpgAPPPKVVGVRVWPKAIPQYLLGHLDVLEAAEKMEKDLGLPgLFLGGNYRGGVALGKCVESGYEAAD 481


                 ...
gi 568910577 386 AVL 388
Cdd:PLN02576 482 LVI 484
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 12-388 1.25e-29

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 119.13  E-value: 1.25e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577   12 ISGLAASYHLIRgpSPPKVILVEGSKRLGGWIRSIRgSDGAIFELGPRGIRPAGA--------LGARTLLLVASLAMDsl 83
Cdd:pfam01593   1 LAGLAAARELLR--AGHDVTVLEARDRVGGRIRTVR-DDGFLIELGAMWFHGAQPpllallkeLGLEDRLVLPDPAPF-- 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577   84 CRGVFAGNSRELSIRSCFPSLFQA----------EQTHRSILLGLLLGAGQSPQPDS-----SLIRQAR-----AERW-- 141
Cdd:pfam01593  76 YTVLFAGGRRYPGDFRRVPAGWEGllefgrllsiPEKLRLGLAALASDALDEFDLDDfslaeSLLFLGRrgpgdVEVWdr 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  142 -----------------------------------------SQWSLRGGLEVLPQALHNHLAskGVTVLSGQPVCGLSLQ 180
Cdd:pfam01593 156 lidpelfaalpfasgafagdpselsaglalpllwallgeggSLLLPRGGLGALPDALAAQLL--GGDVRLNTRVRSIDRE 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  181 PEGRWKVSLGDSSLEADHIISAIPASELSKL-----LPAEAAPLARILstiKAVSVAVVNLQYRGACLPVQgfGHLVPSS 255
Cdd:pfam01593 234 GDGVTVTLTDGEVIEADAVIVTVPLGVLKRIlftppLPPEKARAIRNL---GYGPVNKVHLEFDRKFWPDL--GLLGLLS 308

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  256 EDPTVLGIVYDSVAFPEQDGNPPSLRVTVMLG-GYWLQKLKAaghqLSPELFQQQAQEAAATQLG--LKEPPSHCLVHLH 332
Cdd:pfam01593 309 ELLTGLGTAFSWLTFPNRAPPGKGLLLLVYVGpGDRARELEG----LSDEELLQAVLRDLRKLFGeeAPEPLRVLVSDWH 384

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568910577  333 KNCIP-------QYTIGHWQKLDSAMQFLTaqrlPLTLAGAS----YEGVaVNDCIESGRQAAVAVL 388
Cdd:pfam01593 385 TDPWPrgsyslpQYGPGHDDYRPLARTPDP----GLFFAGEHtstgYPGT-VEGAIESGRRAARAVL 446
PRK12416 PRK12416
protoporphyrinogen oxidase; Provisional
 3-390 5.34e-13

protoporphyrinogen oxidase; Provisional


Pssm-ID: 183516  Cd Length: 463  Bit Score: 70.24  E-value: 5.34e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577   3 RTVIVLGGGISGLAASYHLIRGPS----PPKVILVEGSKRLGGWIRSIR--------GSD-------------------- 50
Cdd:PRK12416   2 KTVVVIGGGITGLSTMFYLEKLKKdyniDLNLILVEKEEYLGGKIHSVEekdfimesGADsivarnehvmplvkdlnlee 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  51 -------GAIFELGPRGIRPAGA-------LGARTLL---LVASLAM-----------------DSLC------------ 84
Cdd:PRK12416  82 emvynetGISYIYSDNTLHPIPSdtifgipMSVESLFsstLVSTKGKivalkdfitknkeftkdTSLAlflesflgkelv 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  85 --------RGVFAGNSRELSIRSCFPSLFQAEQTHRSILLGLLLGAGQspqpdsslIRQARAERWSqwSLRGGLEVLPQA 156
Cdd:PRK12416 162 erqiapvlSGVYSGKLNELTMASTLPYLLDYKNKYGSIIKGFEENKKQ--------FQSAGNKKFV--SFKGGLSTIIDR 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577 157 LHNHLASkgVTVLSGQPVCGLSLQPEgRWKVSL-GDSSLEADHIISAIPASELSKLLpaEAAPLARILSTIKAVSVAVVN 235
Cdd:PRK12416 232 LEEVLTE--TVVKKGAVTTAVSKQGD-RYEISFaNHESIQADYVVLAAPHDIAETLL--QSNELNEQFHTFKNSSLISIY 306

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577 236 LQY--RGACLPVQGFGHLVPSSEDPTVLGIVYDSVAFPEQDGNPPSL-RVTVMLGGYWLQKLKaaghQLSPELFQQQAQE 312
Cdd:PRK12416 307 LGFdiLDEQLPADGTGFIVTENSDLHCDACTWTSRKWKHTSGKQKLLvRMFYKSTNPVYETIK----NYSEEELVRVALY 382

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568910577 313 AAATQLGLKEPPSHCLVHLHKNCIPQYTIGHWQKLDSAMQFLTAQRLPLTLAGASYEGVAVNDCIESGRQAAVAVLGT 390
Cdd:PRK12416 383 DIEKSLGIKGEPEVVEVTNWKDLMPKYHLEHNQAVQSLQEKMMNLYPNIYLAGASYYGVGIGACIGNGKNTANEIIAT 460
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 1-248 3.19e-11

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 64.49  E-value: 3.19e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577   1 MGRTVIVLGGGISGLAASYHLI-RGPsppKVILVEGSKRLGGWIRSIRGSDG----------------AIFEL------- 56
Cdd:COG3349    2 MPPRVVVVGGGLAGLAAAVELAeAGF---RVTLLEARPRLGGRARSFPDPDTglpidngqhvllgcyrNTLDLlrrigaa 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  57 ---------------GPRGIRPAGALGARTLLLVASLAMD--------SLCRGVFAGNSR------ELSIRSCFPSLFQA 107
Cdd:COG3349   79 dnlvgpeplqfplpgGRRWTLRAPRLPAPLHLLRALLRAPglsladrlALLRLLTACRERrwreldDISVADWLRRHGQS 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577 108 EQTHRSILLGLLLGAGQSPQPDSSL------IRQ---ARAERWSQWSLRGGL-EVLPQALHNHLASKGVTVLSGQPVCGL 177
Cdd:COG3349  159 PRLIRRLWEPLLLAALNTPPEQASArlaltvLREtllAGPAASDLLVPRGPLsELFVDPALAYLEARGGEVRLGTRVRAL 238

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568910577 178 SLQpEGRWK--VSLGDSSLEADHIISAIPASELSKLLPA-EAAPLARILSTIKAVSVAVVNLQY-RGACLPVQGF 248
Cdd:COG3349  239 EFD-GGRVTglVLADGETVPADAVVLAVPPEVAARLLPElARLPELGLLAPLEYSPIVNVHLWLdRPVTLGPPPF 312
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
2-239 7.56e-11

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 63.40  E-value: 7.56e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577   2 GRTVIVLGGGISGLAASYHLIR-GPSppkVILVEGSKRLGGWIRSIRGSD-GAIFELGP--------------------- 58
Cdd:COG1231    7 GKDVVIVGAGLAGLAAARELRKaGLD---VTVLEARDRVGGRVWTLRFGDdGLYAELGAmrippshtnllalarelglpl 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  59 --------------RGIRPAGALGARTLLLVASL---AMDSLCRGVFAGNSR-----ELSIRSCFPSLFQAEQTHRSILL 116
Cdd:COG1231   84 epfpnengnallylGGKRVRAGEIAADLRGVAELlakLLRALAAALDPWAHPaaeldRESLAEWLRRNGASPSARRLLGL 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577 117 GLLLGAGQSPQPDSSL--IRQARAERWS--QWSLRGGLEVLPQALHNHLaskGVTVLSGQPVCGLSLQPEGrwkVSL--- 189
Cdd:COG1231  164 LGAGEYGADPDELSLLdlLRYAASAGGGaqQFRIVGGMDQLPRALAAEL---GDRIRLGAPVTRIRQDGDG---VTVttd 237

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 568910577 190 GDSSLEADHIISAIPASELSKL--LPAEAAPLARILSTIKAVSVAVVNLQYR 239
Cdd:COG1231  238 DGGTVRADAVIVTVPPSVLRRIefDPPLPAAKRAAIQRLPYGAAIKVFLQFD 289
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
7-73 9.65e-07

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 45.60  E-value: 9.65e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568910577    7 VLGGGISGLAASYHLIRgpSPPKVILVEGSKRLGGWIRSIRgSDGAIFELGPRGIRPAGALGARTLL 73
Cdd:pfam13450   1 IVGAGLAGLVAAALLAK--RGFRVLVLEKRDRLGGNAYSYR-VPGYVFDYGAHIFHGSDEPNVRDLL 64
PRK07233 PRK07233
hypothetical protein; Provisional
 146-234 2.22e-04

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 42.95  E-value: 2.22e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577 146 LRGGLEVLPQALHNHLASKGVTVLSGQPVCGLSLQPEGRWKVSLGDSSLEADHIISAIPASELSKLLPAEAAPLARILST 225
Cdd:PRK07233 193 LEGGFATLIDALAEAIEARGGEIRLGTPVTSVVIDGGGVTGVEVDGEEEDFDAVISTAPPPILARLVPDLPADVLARLRR 272


                 ....*....
gi 568910577 226 IKAVSVAVV 234
Cdd:PRK07233 273 IDYQGVVCM 281
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
5-200 3.49e-04

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 42.20  E-value: 3.49e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577   5 VIVLGGGISGLAASYHLI-RGPSppkVILVE-------GSKRLGGWIRSirgsdgAIFELGPRGIRPAGALGARTLL-LV 75
Cdd:COG0665    5 VVVIGGGIAGLSTAYHLArRGLD---VTVLErgrpgsgASGRNAGQLRP------GLAALADRALVRLAREALDLWReLA 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  76 ASLAMDSLCR--GVF--AGNSRELsirscfpSLFQAEQTHRsillglllgagQSPQPDSSLIRQARA-ERWSQWS---LR 147
Cdd:COG0665   76 AELGIDCDFRrtGVLylARTEAEL-------AALRAEAEAL-----------RALGLPVELLDAAELrEREPGLGspdYA 137

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568910577 148 GGLEV----------LPQALHNHLASKGVTVLSGQPVCGLSLQPEGRWKVSLGDSSLEADHII 200
Cdd:COG0665  138 GGLYDpddghvdpakLVRALARAARAAGVRIREGTPVTGLEREGGRVTGVRTERGTVRADAVV 200
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 5-42 4.37e-04

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 42.16  E-value: 4.37e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 568910577   5 VIVLGGGISGLAASYHLIR-GPSppkVILVEGSKRLGG-W 42
Cdd:COG2072    9 VVVIGAGQAGLAAAYHLRRaGID---FVVLEKADDVGGtW 45
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 1-58 9.90e-04

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 40.99  E-value: 9.90e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 568910577   1 MGRTVIVLGGGISGLAASYHLIR-GpspPKVILVEGSKRLGGWIRSIRgSDGAIFELGP 58
Cdd:COG1233    2 MMYDVVVIGAGIGGLAAAALLARaG---YRVTVLEKNDTPGGRARTFE-RPGFRFDVGP 56
PRK07233 PRK07233
hypothetical protein; Provisional
 4-41 1.10e-03

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 41.03  E-value: 1.10e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 568910577   4 TVIVLGGGISGLAASYHLIRgpSPPKVILVEGSKRLGG 41
Cdd:PRK07233   1 KIAIVGGGIAGLAAAYRLAK--RGHEVTVFEADDQLGG 36
PLN02268 PLN02268
probable polyamine oxidase
 4-43 1.42e-03

probable polyamine oxidase


Pssm-ID: 177909 [Multi-domain]  Cd Length: 435  Bit Score: 40.44  E-value: 1.42e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 568910577   4 TVIVLGGGISGLAASYHLIRgpSPPKVILVEGSKRLGGWI 43
Cdd:PLN02268   2 SVIVIGGGIAGIAAARALHD--ASFKVTLLESRDRIGGRV 39
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 5-281 1.50e-03

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 40.46  E-value: 1.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577    5 VIVLGGGISGLAASYHLIRgpSPPKVILVEG--------SKRLGGWIRSirgsdgaifELGPRGIRPAGALGARTLLLVA 76
Cdd:pfam01266   2 VVVIGGGIVGLSTAYELAR--RGLSVTLLERgddpgsgaSGRNAGLIHP---------GLRYLEPSELARLALEALDLWE 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577   77 SLAmdslcrgvfAGNSRELSIRSCFpsLFQAEQTHRSILLGLLLGAGQSPQPDSSLIRQARAERWSQWS--LRGGLEV-- 152
Cdd:pfam01266  71 ELE---------EELGIDCGFRRCG--VLVLARDEEEEALEKLLAALRRLGVPAELLDAEELRELEPLLpgLRGGLFYpd 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568910577  153 --------LPQALHNHLASKGVTVLSGQPVCGLSlQPEGRWKVSLGDsslEADHIISAipASELSKLLPaeAAPLARILS 224
Cdd:pfam01266 140 gghvdparLLRALARAAEALGVRIIEGTEVTGIE-EEGGVWGVVTTG---EADAVVNA--AGAWADLLA--LPGLRLPVR 211

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568910577  225 TIKAVSVAVVNLQYRGACLPVQGFG------HLVPSSEDPTVLGIVYDSVAFPEQDGNPPSLR 281
Cdd:pfam01266 212 PVRGQVLVLEPLPEALLILPVPITVdpgrgvYLRPRADGRLLLGGTDEEDGFDDPTPDPEEIE 274
YdhS COG4529
Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];
3-40 3.12e-03

Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];


Pssm-ID: 443597 [Multi-domain]  Cd Length: 466  Bit Score: 39.55  E-value: 3.12e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 568910577   3 RTVIVLGGGISGLAASYHLIR-GPSPPKVILVEGSKRLG 40
Cdd:COG4529    6 KRIAIIGGGASGTALAIHLLRrAPEPLRITLFEPRPELG 44
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 2-44 3.18e-03

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 39.47  E-value: 3.18e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 568910577   2 GRTVIVLGGGISGLAASYHLIR-GPSppkVILVEGSKRLGGWIR 44
Cdd:PRK12771 137 GKRVAVIGGGPAGLSAAYHLRRmGHA---VTIFEAGPKLGGMMR 177
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
3-47 3.44e-03

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 39.46  E-value: 3.44e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 568910577   3 RTVIVLGGGISGLAASYHL----IrgpsppKVILVEGSKRLGGWIRSIR 47
Cdd:COG1148  141 KRALVIGGGIAGMTAALELaeqgY------EVYLVEKEPELGGRAAQLH 183
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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