|
Name |
Accession |
Description |
Interval |
E-value |
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
173-1606 |
7.11e-114 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 400.93 E-value: 7.11e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 173 YWKNGFVAFQTAINAAIievTTNHSVMEELISVVGINMRTPPFISKGESI--NEWF-IFICIVY-FSPFVYVASLNITKE 248
Cdd:TIGR01257 603 YIWGGFAYLQDMVEQGI---TRSQMQAEPPVGIYLQQMPYPCFVDDSFMIilNRCFpIFMVLAWiYSVSMTVKSIVLEKE 679
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 249 RKkFKKLMTAMGLQQSAFWLSWalmyagFVFVVSIfMTLVIKLFQMVILTGFVVLVS------LFTL-YGLSLIALAFLL 321
Cdd:TIGR01257 680 LR-LKETLKNQGVSNAVIWCTW------FLDSFSI-MSMSIFLLTIFIMHGRILHYSdpfilfLFLLaFSTATIMQCFLL 751
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 322 CVLIKRPIL----TGVVgsLFTVFWGCLGFTALYRQLPSSLGWALCLFSPFAFTAGVAQISHQEYHVSGVVFPD-----P 392
Cdd:TIGR01257 752 STFFSKASLaaacSGVI--YFTLYLPHILCFAWQDRMTADLKTAVSLLSPVAFGFGTEYLVRFEEQGLGLQWSNignspL 829
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 393 SGESYTMIVIFFLLAFDTLLYLTLTLYFEHILPDESGQRHSPLFFLKSSFWSQHKNTHHEVFGNEMNSELSCDDSFEPVS 472
Cdd:TIGR01257 830 EGDEFSFLLSMKMMLLDAALYGLLAWYLDQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTEPLTEEMEDPEH 909
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 473 PE-----FHRKE------AIRIRNLRK--EYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEG 539
Cdd:TIGR01257 910 PEgindsFFERElpglvpGVCVKNLVKifEPSGRP----AVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSG 985
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 540 SATIYNTQLSeiINMEEIRNYTGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELS 619
Cdd:TIGR01257 986 TVLVGGKDIE--TNLDAVRQSLGMCPQHNILFHHLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS 1063
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 620 GGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:TIGR01257 1064 GGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGT 1143
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 700 SLFLKRKWGIGYHLSLHR-----------------------NERC---------------NTERITSLITQHISDAKLTA 741
Cdd:TIGR01257 1144 PLFLKNCFGTGFYLTLVRkmkniqsqrggcegtcsctskgfSTRCparvdeitpeqvldgDVNELMDLVYHHVPEAKLVE 1223
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 742 ENEEKLVYTLPLE--RTDKFPDLCRDLENS-SDQGIMSFGVSMTTLNEVFL---------------------NLKGRSAI 797
Cdd:TIGR01257 1224 CIGQELIFLLPNKnfKQRAYASLFRELEETlADLGLSSFGISDTPLEEIFLkvtedadsgslfaggaqqkreNANLRHPC 1303
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 798 NGPDPGVGGLAEIDVTRDPGAESEAQQALGSlPEVK----QAASSAALWRRQVCAVARLRFLKLRNERKIFLSLLV---- 869
Cdd:TIGR01257 1304 SGPTEKAGQTPQASHTCSPGQPAAHPEGQPP-PEPEdpgvPLNTGARLILQHVQALLVKRFQHTIRSHKDFLAQIVlpat 1382
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 870 -VFgIAL-----IPTVCE--KIVYSVYFHDHRWEF--------------------SPGMYFRSLEQ--LPQPPLTNLLII 919
Cdd:TIGR01257 1383 fVF-LALmlsiiIPPFGEypALTLHPWMYGQQYTFfsmdepnsehlevladvllnKPGFGNRCLKEewLPEYPCGNSTPW 1461
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 920 nNTGSSIEDAVQSLKHQNLVLE---------------------------------------VDDARNRNGSD-------- 952
Cdd:TIGR01257 1462 -KTPSVSPNITHLFQKQKWTAAhpspscrcstrekltmlpecpegagglpppqrtqrsteiLQDLTDRNISDflvktypa 1540
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 953 -------------DPSYNGAII--------------------------VSGG-----------------HRDYRFSVACN 976
Cdd:TIGR01257 1541 lirsslkskfwvnEQRYGGISIggklpaipitgealvgflsdlgqmmnVSGGpvtreaskempdflkhlETEDNIKVWFN 1620
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 977 TKRMNCFPVLIGIVSNALLgifnvtelikteRSTFPPD-NP-RWGMGLLDFLLLLVVNCLSPYIGMSS------------ 1042
Cdd:TIGR01257 1621 NKGWHALVSFLNVAHNAIL------------RASLPKDrDPeEYGITVISQPLNLTKEQLSEITVLTTsvdavvaicvif 1688
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1043 -------------VSDYKQKAQSQLRISGLCPSAYWCGQALVDIPFYfgiLVSIHLMYYIFL----ESTIVLQFMFALVV 1105
Cdd:TIGR01257 1689 amsfvpasfvlylIQERVNKAKHLQFISGVSPTTYWLTNFLWDIMNY---AVSAGLVVGIFIgfqkKAYTSPENLPALVA 1765
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1106 CVASCAACLILLTYVISFLF--PSgrknNGFWSLSffLISLFMLIllglthseniiiiciilipSCTSVFFLVQMIELSS 1183
Cdd:TIGR01257 1766 LLMLYGWAVIPMMYPASFLFdvPS----TAYVALS--CANLFIGI-------------------NSSAITFVLELFENNR 1820
|
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1184 MYHRRsesqdpekSATGKMILPIFiPYLQI---IVFLFIIRCLEMKYGK--ETMRKDPFFRISPRRGEYRPNPEEPEEED 1258
Cdd:TIGR01257 1821 TLLRF--------NAMLRKLLIVF-PHFCLgrgLIDLALSQAVTDVYAQfgEEHSANPFQWDLIGKNLVAMAVEGVVYFL 1891
|
1370 1380 1390 1400 1410 1420 1430 1440
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1259 EDVQTERVKTANALTASSLDEPVIMASclhKEYKQEKKRCFS-ARKT----------------KTAVRNVSFCINKGEVL 1321
Cdd:TIGR01257 1892 LTLLIQHHFFLSRWIAEPAKEPIFDED---DDVAEERQRIISgGNKTdilrlneltkvysgtsSPAVDRLCVGVRPGECF 1968
|
1450 1460 1470 1480 1490 1500 1510 1520
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1322 GLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTRQAGGGFRHLGYCPQEDVLWPDLTVREHLDLYSAVKGLTKEE 1401
Cdd:TIGR01257 1969 GLLGVNGAGKTTTFKMLTGDTTVTSGDATV--AGKSILTNISDVHQNMGYCPQFDAIDDLLTGREHLYLYARLRGVPAEE 2046
|
1530 1540 1550 1560 1570 1580 1590 1600
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1402 ---------AALSVSRLADALklqdqmalpAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIV 1472
Cdd:TIGR01257 2047 iekvanwsiQSLGLSLYADRL---------AGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSII 2117
|
1610 1620 1630 1640 1650 1660 1670 1680
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1473 KsSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLKSKFGKDYLLEVKVKA-----LTLVEPLHMEILKLFPQA 1547
Cdd:TIGR01257 2118 R-EGRAVVLTSHSMEECEALCTRLAIMVKGAFQCLGTIQHLKSKFGDGYIVTMKIKSpkddlLPDLNPVEQFFQGNFPGS 2196
|
1690 1700 1710 1720 1730
....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 1548 ARQERYSFVMAYKLAIEDvhpLSQTFSKLEAVKQAFDLEEYSLSQATLEQVFLELSKEQ 1606
Cdd:TIGR01257 2197 VQRERHYNMLQFQVSSSS---LARIFQLLISHKDSLLIEEYSVTQTTLDQVFVNFAKQQ 2252
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
1287-1514 |
1.21e-85 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 279.00 E-value: 1.21e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1287 LHKEYKqekkrcfsaRKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD-SGTPPTRQAggg 1365
Cdd:cd03263 6 LTKTYK---------KGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGySIRTDRKAA--- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1366 FRHLGYCPQEDVLWPDLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPA 1445
Cdd:cd03263 74 RQSLGYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPS 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 1446 LLLLDEPTTGMDPEGQLQMWQAIQAIVKSsaRGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLK 1514
Cdd:cd03263 154 VLLLDEPTSGLDPASRRAIWDLILEVRKG--RSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
481-704 |
2.45e-81 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 266.68 E-value: 2.45e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEKveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiiNMEEIRNY 560
Cdd:cd03263 1 LQIRNLTKTYKKGTKP--AVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRT--DRKAARQS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLL 640
Cdd:cd03263 77 LGYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1387227070 641 LDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGSSLFLK 704
Cdd:cd03263 157 LDEPTSGLDPASRRAIWDLILEVRKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
1303-1517 |
3.36e-71 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 238.42 E-value: 3.36e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1303 KTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAG-VVVFrdsGTPPTRQAGGGFRHLGYCPQEDVLWPD 1381
Cdd:COG1131 11 GDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGeVRVL---GEDVARDPAEVRRRIGYVPQEPALYPD 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 LTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQ 1461
Cdd:COG1131 88 LTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEPTSGLDPEAR 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 1462 LQMWQAIQAIVkssARGA--LLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLKSKF 1517
Cdd:COG1131 168 RELWELLRELA---AEGKtvLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKARL 222
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
481-699 |
1.21e-65 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 222.25 E-value: 1.21e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiiNMEEIRNY 560
Cdd:COG1131 1 IEVRGLTKRYGDKT----ALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVAR--DPAEVRRR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLL 640
Cdd:COG1131 75 IGYVPQEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLI 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 641 LDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:COG1131 155 LDEPTSGLDPEARRELWELLRElAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGT 214
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
1281-1530 |
3.72e-56 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 195.46 E-value: 3.72e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1281 VIMASCLHKEYKQekkrcfsarktKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTR 1360
Cdd:COG4555 1 MIEVENLSKKYGK-----------VPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILI--DGEDVRK 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1361 QAGGGFRHLGYCPQEDVLWPDLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSV 1440
Cdd:COG4555 68 EPREARRQIGVLPDERGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARAL 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1441 LGSPALLLLDEPTTGMDPEGQLQMWQAIQAIvKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLKSKFGKD 1520
Cdd:COG4555 148 VHDPKVLLLDEPTNGLDVMARRLLREILRAL-KKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEIGEE 226
|
250
....*....|
gi 1387227070 1521 YLLEVKVKAL 1530
Cdd:COG4555 227 NLEDAFVALI 236
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
1303-1504 |
6.64e-56 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 191.84 E-value: 6.64e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1303 KTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTRQAGGGFRHLGYCPQEDVLWPDL 1382
Cdd:cd03230 11 GKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKV--LGKDIKKEPEEVKRRIGYLPEEPSLYENL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1383 TVREHLDLysavkgltkeeaalsvSRladalklqdqmalpakalpeGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQL 1462
Cdd:cd03230 89 TVRENLKL----------------SG--------------------GMKQRLALAQALLHDPELLILDEPTSGLDPESRR 132
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1387227070 1463 QMWQAIQAIVKssaRGA--LLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:cd03230 133 EFWELLRELKK---EGKtiLLSSHILEEAERLCDRVAILNNGRI 173
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
481-699 |
1.22e-53 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 188.14 E-value: 1.22e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKgkpeKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINmeEIRNY 560
Cdd:COG4555 2 IEVENLSKKYG----KVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPR--EARRQ 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLL 640
Cdd:COG4555 76 IGVLPDERGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLL 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 641 LDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:COG4555 156 LDEPTNGLDVMARRLLREILRAlKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGS 215
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
1306-1514 |
7.31e-53 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 184.88 E-value: 7.31e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1306 TAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAG-VVVFrdsGTPPTRQAGGGFRHLGYCPQEDVLWPDLTV 1384
Cdd:cd03265 14 EAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGrATVA---GHDVVREPREVRRRIGIVFQDLSVDDELTG 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1385 REHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQM 1464
Cdd:cd03265 91 WENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTIGLDPQTRAHV 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1465 WQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLK 1514
Cdd:cd03265 171 WEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEELK 220
|
|
| drrA |
TIGR01188 |
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ... |
1307-1602 |
9.59e-53 |
|
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]
Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 187.98 E-value: 9.59e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVvfRDSGTPPTRQAGGGFRHLGYCPQEDVLWPDLTVRE 1386
Cdd:TIGR01188 8 AVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTA--RVAGYDVVREPRKVRRSIGIVPQYASVDEDLTGRE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1387 HLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQ 1466
Cdd:TIGR01188 86 NLEMMGRLYGLPKDEAEERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPRTRRAIWD 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1467 AIQAIvKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLKSKFGKDYLLEVKVKALTLVEPLHMEILKLFPQ 1546
Cdd:TIGR01188 166 YIRAL-KEEGVTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEELKRRLGKDTLESRPRDIQSLKVEVSMLIAELGET 244
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 1547 AarqerysfvmaykLAIEDVHPLSQTFSKL-----EAVKQAFD--------LEEYSLSQATLEQVFLEL 1602
Cdd:TIGR01188 245 G-------------LGLLAVTVDSDRIKILvpdgdETVPEIVEaairngirIRSISTERPSLDDVFLKL 300
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
481-694 |
6.23e-51 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 177.59 E-value: 6.23e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiiNMEEIRNY 560
Cdd:cd03230 1 IEVRNLSKRYGKKT----ALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKK--EPEEVKRR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFLTVRENLRLfakikgippkeveqevksimmeldmhniqdviakelSGGQKRKLTFGIAILGDPQVLL 640
Cdd:cd03230 75 IGYLPEEPSLYENLTVRENLKL------------------------------------SGGMKQRLALAQALLHDPELLI 118
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 641 LDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:cd03230 119 LDEPTSGLDPESRREFWELLRElKKEGKTILLSSHILEEAERLCDRVAILNNGRI 173
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1304-1607 |
1.30e-48 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 175.68 E-value: 1.30e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1304 TKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRdsGTPPTRQAGggfRHLGYCPQEDVLWPDLT 1383
Cdd:COG4152 13 DKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWD--GEPLDPEDR---RRIGYLPEERGLYPKMK 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1384 VREHLdLYSA-VKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQL 1462
Cdd:COG4152 88 VGEQL-VYLArLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELLILDEPFSGLDPVNVE 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1463 QMWQAIQAIVkssARGA--LLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLKSKFGKdyllevkvKALTLVEPLHMEI 1540
Cdd:COG4152 167 LLKDVIRELA---AKGTtvIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEIRRQFGR--------NTLRLEADGDAGW 235
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 1541 LKLFPQAARQERYSFVMAYKLAIEDVhplSQTFskLEAVKQAFDLEEYSLSQATLEQVFLELSKEQE 1607
Cdd:COG4152 236 LRALPGVTVVEEDGDGAELKLEDGAD---AQEL--LRALLARGPVREFEEVRPSLNEIFIEVVGEKA 297
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
481-694 |
3.60e-47 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 168.44 E-value: 3.60e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNT---QLSEIINMEEI 557
Cdd:cd03255 1 IELKNLSKTYGGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTdisKLSEKELAAFR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 558 RNYTGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQ 637
Cdd:cd03255 81 RRHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 638 VLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADiLADRKVFLSNGKL 694
Cdd:cd03255 161 IILADEPTGNLDSETGKEVMELLRElnKEAGTTIVVVTHDPELAE-YADRIIELRDGKI 218
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
1303-1508 |
6.80e-47 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 167.46 E-value: 6.80e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1303 KTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPPTRQagggfRHLGYCPQEDVLWPDL 1382
Cdd:cd03269 11 GRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIAAR-----NRIGYLPEERGLYPKM 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1383 TVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQL 1462
Cdd:cd03269 86 KVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSGLDPVNVE 165
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1387227070 1463 QMWQAIQAIvKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIG 1508
Cdd:cd03269 166 LLKDVIREL-ARAGKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1287-1605 |
8.75e-45 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 165.65 E-value: 8.75e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1287 LHKEYK-QEKKRCFSA---------RKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVvfrdsgt 1356
Cdd:COG4586 7 LSKTYRvYEKEPGLKGalkglfrreYREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEV------- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1357 pptrqagggfRHLGYCPQED----------V------LWPDLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMA 1420
Cdd:COG4586 80 ----------RVLGYVPFKRrkefarrigvVfgqrsqLWWDLPAIDSFRLLKAIYRIPDAEYKKRLDELVELLDLGELLD 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1421 LPAkalpegakRKLS--------FALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSsaRGA--LLTTHSMAEAE 1490
Cdd:COG4586 150 TPV--------RQLSlgqrmrceLAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRE--RGTtiLLTSHDMDDIE 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1491 AVCDRVAIMVSGRLRCIGSVQHLKSKFGKDYLLEVkvkalTLVEPLHMEILKLFPQAARQERYSfvmaYKLAIEDVHPLS 1570
Cdd:COG4586 220 ALCDRVIVIDHGRIIYDGSLEELKERFGPYKTIVL-----ELAEPVPPLELPRGGEVIEREGNR----VRLEVDPRESLA 290
|
330 340 350
....*....|....*....|....*....|....*
gi 1387227070 1571 QTFSKLEAvkqAFDLEEYSLSQATLEQVFLELSKE 1605
Cdd:COG4586 291 EVLARLLA---RYPVRDLTIEEPPIEEVIRRIYKE 322
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
481-699 |
4.08e-44 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 160.19 E-value: 4.08e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYkgkPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRNY 560
Cdd:COG1122 1 IELENLSFSY---PGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKK-NLRELRRK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQF-NIYFDFLTVRENLrLFA-KIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLtfgiAILG---- 634
Cdd:COG1122 77 VGLVFQNpDDQLFAPTVEEDV-AFGpENLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRV----AIAGvlam 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 635 DPQVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:COG1122 152 EPEVLVLDEPTAGLDPRGRRELLELLKRlNKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGT 217
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
481-695 |
3.94e-43 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 156.58 E-value: 3.94e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKpekvEALQGICLDVYEGqLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiiNMEEIRNY 560
Cdd:cd03264 1 LQLENLTKRYGKK----RALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLK--QPQKLRRR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQ-FNIYFDFlTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVL 639
Cdd:cd03264 74 IGYLPQeFGVYPNF-TVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSIL 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 640 LLDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTQFMDEADILADRKVFLSNGKLR 695
Cdd:cd03264 153 IVDEPTAGLDPEERIRFRNLLSELGEDRIVILSTHIVEDVESLCNQVAVLNKGKLV 208
|
|
| drrA |
TIGR01188 |
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ... |
496-793 |
5.37e-43 |
|
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]
Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 159.48 E-value: 5.37e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 496 KVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLseIINMEEIRNYTGFCPQFNIYFDFLT 575
Cdd:TIGR01188 5 DFKAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGYDV--VREPRKVRRSIGIVPQYASVDEDLT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 576 VRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHL 655
Cdd:TIGR01188 83 GRENLEMMGRLYGLPKDEAEERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPRTRRA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 656 VWNFL-KERKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGSSLFLKRKWGiGYHLSLHRNERC-----NTERITSL 729
Cdd:TIGR01188 163 IWDYIrALKEEGVTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEELKRRLG-KDTLESRPRDIQslkveVSMLIAEL 241
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 730 ITQHISDAKLTAENEEKLVYTLPLERTdkfpdLCRDLENSSDQG--IMSFGVSMTTLNEVFLNLKG 793
Cdd:TIGR01188 242 GETGLGLLAVTVDSDRIKILVPDGDET-----VPEIVEAAIRNGirIRSISTERPSLDDVFLKLTG 302
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
478-694 |
7.76e-42 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 153.66 E-value: 7.76e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 478 KEAIRIRNLRKEYKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYN---TQLSEIiNM 554
Cdd:COG1136 2 SPLLELRNLTKSYGTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGqdiSSLSER-EL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 555 EEIRNYT-GFCPQ-FNIyFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQK------Rkl 626
Cdd:COG1136 81 ARLRRRHiGFVFQfFNL-LPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQqrvaiaR-- 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 627 tfgiAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADIlADRKVFLSNGKL 694
Cdd:COG1136 158 ----ALVNRPKLILADEPTGNLDSKTGEEVLELLRElnRELGTTIVMVTHDPELAAR-ADRVIRLRDGRI 222
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
481-704 |
8.49e-42 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 153.29 E-value: 8.49e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGkpekVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNtqLSEIINMEEIRNY 560
Cdd:cd03265 1 IEVENLVKKYGD----FEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAG--HDVVREPREVRRR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLL 640
Cdd:cd03265 75 IGIVFQDLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLF 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 641 LDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGSSLFLK 704
Cdd:cd03265 155 LDEPTIGLDPQTRAHVWEYIEKlkEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEELK 220
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
481-695 |
2.65e-41 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 151.22 E-value: 2.65e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNtqlSEIINMEEIRNY 560
Cdd:cd03268 1 LKTNDLTKTYGKKR----VLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDG---KSYQKNIEALRR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQevksIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLL 640
Cdd:cd03268 74 IGALIEAPGFYPNLTARENLRLLARLLGIRKKRIDE----VLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLI 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 641 LDEPTAGLDPFSRHLVWNFL-KERKTNHTILFSTQFMDEADILADRKVFLSNGKLR 695
Cdd:cd03268 150 LDEPTNGLDPDGIKELRELIlSLRDQGITVLISSHLLSEIQKVADRIGIINKGKLI 205
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
1305-1603 |
6.14e-41 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 153.81 E-value: 6.14e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVvfRDSGTPPTRQAGGGFRHLGYCPQEDVLWPDLTV 1384
Cdd:PRK13537 20 KLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSI--SLCGEPVPSRARHARQRVGVVPQFDNLDPDFTV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1385 REHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQM 1464
Cdd:PRK13537 98 RENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTTGLDPQARHLM 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1465 WQAIQAIVkssARGA--LLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHL-KSKFGKDyLLEVKVKALtlvEPLHMEil 1541
Cdd:PRK13537 178 WERLRSLL---ARGKtiLLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHALiESEIGCD-VIEIYGPDP---VALRDE-- 248
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 1542 kLFPQAARQE-RYSFVMAYklaIEDVHPLsqtfskLEAVKQAFDLeEYSLSQATLEQVFLELS 1603
Cdd:PRK13537 249 -LAPLAERTEiSGETLFCY---VRDPEPL------HARLKGRAGL-RYLHRPANLEDVFLRLT 300
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
482-693 |
2.01e-40 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 149.15 E-value: 2.01e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 482 RIRNLRKEYKGKPEKveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRNYT 561
Cdd:cd03225 1 ELKNLSFSYPDGARP--ALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKL-SLKELRRKV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 562 GFCPQF-NIYFDFLTVRENLrLFA-KIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVL 639
Cdd:cd03225 78 GLVFQNpDDQFFGPTVEEEV-AFGlENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDIL 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 640 LLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGK 693
Cdd:cd03225 157 LLDEPTAGLDPAGRRELLELLKKlKAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
1282-1508 |
3.58e-40 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 148.67 E-value: 3.58e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1282 IMASCLHKEYKQEKKRCfsarktkTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVV---FRDSGTPp 1358
Cdd:cd03266 2 ITADALTKRFRDVKKTV-------QAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATvdgFDVVKEP- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1359 tRQAGggfRHLGYCPQEDVLWPDLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFAL 1438
Cdd:cd03266 74 -AEAR---RRLGFVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIAR 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1439 SVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIvKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIG 1508
Cdd:cd03266 150 ALVHDPPVLLLDEPTTGLDVMATRALREFIRQL-RALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
481-691 |
5.60e-40 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 148.00 E-value: 5.60e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSeiinmeEIRNY 560
Cdd:cd03293 1 LEVRNVSKTYGGGGGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVT------GPGPD 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLL 640
Cdd:cd03293 75 RGYVFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 641 LDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSN 691
Cdd:cd03293 155 LDEPFSALDALTREQLQEELLDiwRETGKTVLLVTHDIDEAVFLADRVVVLSA 207
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
481-698 |
2.51e-39 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 145.97 E-value: 2.51e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiiNMEEIRNY 560
Cdd:cd03266 2 ITADALTKRFRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVK--EPAEARRR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLL 640
Cdd:cd03266 80 LGFVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLL 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 641 LDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAG 698
Cdd:cd03266 160 LDEPTTGLDVMATRALREFIRQlRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
1306-1504 |
3.26e-39 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 147.11 E-value: 3.26e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1306 TAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPTRQAGGG----FRHLGycpqedvL 1378
Cdd:COG0411 18 VAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGrdiTGLPPHRIARLGiartFQNPR-------L 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1379 WPDLTVREHLDL-------YSAVKGLT------KEEAALS--VSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGS 1443
Cdd:COG0411 91 FPELTVLENVLVaaharlgRGLLAALLrlprarREEREARerAEELLERVGLADRADEPAGNLSYGQQRRLEIARALATE 170
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 1444 PALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:COG0411 171 PKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADRIVVLDFGRV 231
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
1309-1484 |
4.61e-39 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 144.93 E-value: 4.61e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1309 RNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRdsGTPPTRQAGGGFRHLGYCPQEDVLWPDLTVREHL 1388
Cdd:COG4133 19 SGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWN--GEPIRDAREDYRRRLAYLGHADGLKPELTVRENL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1389 DLYSAVKGLTKEEAAlsVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAI 1468
Cdd:COG4133 97 RFWAALYGLRADREA--IDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPFTALDAAGVALLAELI 174
|
170
....*....|....*..
gi 1387227070 1469 QAivKSSARGA-LLTTH 1484
Cdd:COG4133 175 AA--HLARGGAvLLTTH 189
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
1306-1504 |
5.58e-39 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 145.66 E-value: 5.58e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1306 TAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPTRQAGGG----FRHLGycpqedvL 1378
Cdd:cd03219 14 VALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGediTGLPPHEIARLGigrtFQIPR-------L 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1379 WPDLTVRE--------HLDLYSAVKGLTKEEAALS--VSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLL 1448
Cdd:cd03219 87 FPELTVLEnvmvaaqaRTGSGLLLARARREEREARerAEELLERVGLADLADRPAGELSYGQQRRLEIARALATDPKLLL 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 1449 LDEPTTGMDPEGQLQMWQAIQAIvKSSARGALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:cd03219 167 LDEPAAGLNPEETEELAELIREL-RERGITVLLVEHDMDVVMSLADRVTVLDQGRV 221
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
1303-1505 |
5.88e-39 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 144.67 E-value: 5.88e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1303 KTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPPTRQAgggFRHLGYCPQEDVLWPDL 1382
Cdd:cd03268 11 GKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIEA---LRRIGALIEAPGFYPNL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1383 TVREHLDLYSAVKGLTKEEaalsVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQL 1462
Cdd:cd03268 88 TARENLRLLARLLGIRKKR----IDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNGLDPDGIK 163
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1387227070 1463 QMWQAIQAIvKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLR 1505
Cdd:cd03268 164 ELRELILSL-RDQGITVLISSHLLSEIQKVADRIGIINKGKLI 205
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
1305-1503 |
9.75e-39 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 148.44 E-value: 9.75e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRdsGTPPTRQAGGGFRHLGYCPQEDVLWPDLTV 1384
Cdd:PRK13536 54 KAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVL--GVPVPARARLARARIGVVPQFDNLDLEFTV 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1385 REHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQM 1464
Cdd:PRK13536 132 RENLLVFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLILDEPTTGLDPHARHLI 211
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1387227070 1465 WQAIQAIVkssARGA--LLTTHSMAEAEAVCDRVAIMVSGR 1503
Cdd:PRK13536 212 WERLRSLL---ARGKtiLLTTHFMEEAERLCDRLCVLEAGR 249
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
1305-1505 |
2.52e-38 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 143.10 E-value: 2.52e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGeVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTRQAGGGFRHLGYCPQEDVLWPDLTV 1384
Cdd:cd03264 13 KRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRI--DGQDVLKQPQKLRRRIGYLPQEFGVYPNFTV 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1385 REHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQM 1464
Cdd:cd03264 90 REFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTAGLDPEERIRF 169
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1387227070 1465 WQAIQAIvkSSARGALLTTHSMAEAEAVCDRVAIMVSGRLR 1505
Cdd:cd03264 170 RNLLSEL--GEDRIVILSTHIVEDVESLCNQVAVLNKGKLV 208
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
1282-1504 |
3.53e-38 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 143.63 E-value: 3.53e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1282 IMASCLHKEYKQEKK--------RCFSARK--TKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVvf 1351
Cdd:cd03267 1 IEVSNLSKSYRVYSKepgligslKSLFKRKyrEVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEV-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1352 RDSGTPPTRQAGGGFRHLGYC-PQEDVLWPDLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGA 1430
Cdd:cd03267 79 RVAGLVPWKRRKKFLRRIGVVfGQKTQLWWDLPVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQ 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1387227070 1431 KRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:cd03267 159 RMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRL 232
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
456-693 |
2.51e-36 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 141.51 E-value: 2.51e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 456 NEMNSELSCDDSFEPVSPEFHRKE--AIRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGW 533
Cdd:PRK13536 15 ELSPIERKHQGISEAKASIPGSMStvAIDLAGVSKSYGDKA----VVNGLSFTVASGECFGLLGPNGAGKSTIARMILGM 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 534 SACTEGSATIYNTQLSEIINMEEIRnyTGFCPQF-NIYFDFlTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQD 612
Cdd:PRK13536 91 TSPDAGKITVLGVPVPARARLARAR--IGVVPQFdNLDLEF-TVRENLLVFGRYFGMSTREIEAVIPSLLEFARLESKAD 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 613 VIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKT-NHTILFSTQFMDEADILADRKVFLSN 691
Cdd:PRK13536 168 ARVSDLSGGMKRRLTLARALINDPQLLILDEPTTGLDPHARHLIWERLRSLLArGKTILLTTHFMEEAERLCDRLCVLEA 247
|
..
gi 1387227070 692 GK 693
Cdd:PRK13536 248 GR 249
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
480-692 |
4.62e-36 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 138.30 E-value: 4.62e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLseiinmEEIRN 559
Cdd:COG1116 7 ALELRGVSKRFPTGGGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPV------TGPGP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YTGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSImmeLDMHNIQDVIAK---ELSGGQKRKLtfGIA--ILG 634
Cdd:COG1116 81 DRGVVFQEPALLPWLTVLDNVALGLELRGVPKAERRERAREL---LELVGLAGFEDAyphQLSGGMRQRV--AIAraLAN 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 635 DPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNG 692
Cdd:COG1116 156 DPEVLLMDEPFGALDALTRERLQDELLRlwQETGKTVLFVTHDVDEAVFLADRVVVLSAR 215
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
1303-1509 |
1.01e-35 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 136.13 E-value: 1.01e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1303 KTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPTRQAGGGfrhLGYCPQEDVLW 1379
Cdd:cd03218 11 GKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGqdiTKLPMHKRARLG---IGYLPQEASIF 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1380 PDLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPE 1459
Cdd:cd03218 88 RKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDEPFAGVDPI 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1460 GqLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGS 1509
Cdd:cd03218 168 A-VQDIQKIIKILKDRGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGT 216
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
1298-1524 |
1.49e-35 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 135.54 E-value: 1.49e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1298 CFSARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRdsGTPPTRQAGGGFR-HLGYCPQEd 1376
Cdd:COG1122 7 SFSYPGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVD--GKDITKKNLRELRrKVGLVFQN- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1377 vlwPDL-----TVRE-------HLdlysavkGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFAlSVLG-S 1443
Cdd:COG1122 84 ---PDDqlfapTVEEdvafgpeNL-------GLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIA-GVLAmE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1444 PALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSaRGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLkskFGKDYLL 1523
Cdd:COG1122 153 PEVLVLDEPTAGLDPRGRRELLELLKRLNKEG-KTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREV---FSDYELL 228
|
.
gi 1387227070 1524 E 1524
Cdd:COG1122 229 E 229
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
482-693 |
1.77e-35 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 132.75 E-value: 1.77e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 482 RIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINmEEIRNYT 561
Cdd:cd00267 1 EIENLSFRYGGRT----ALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPL-EELRRRI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 562 GFCPQfniyfdfltvrenlrlfakikgippkeveqevksimmeldmhniqdviakeLSGGQKRKLTFGIAILGDPQVLLL 641
Cdd:cd00267 76 GYVPQ---------------------------------------------------LSGGQRQRVALARALLLNPDLLLL 104
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 642 DEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGK 693
Cdd:cd00267 105 DEPTSGLDPASRERLLELLRElAEEGRTVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
1308-1454 |
2.94e-35 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 132.00 E-value: 2.94e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1308 VRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRdsGTPPTRQAGGGFR-HLGYCPQEDVLWPDLTVRE 1386
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLD--GQDLTDDERKSLRkEIGYVFQDPQLFPRLTVRE 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 1387 HLDLYSAVKGLTKEEAAlsvSRLADALKLQDQMALPAKALPE-------GAKRKLSFALSVLGSPALLLLDEPTT 1454
Cdd:pfam00005 79 NLRLGLLLKGLSKREKD---ARAEEALEKLGLGDLADRPVGErpgtlsgGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
481-698 |
3.10e-35 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 133.95 E-value: 3.10e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKgkpeKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiinmeEIRNY 560
Cdd:cd03269 1 LEVENVTKRFG----RVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDI-----AARNR 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLL 640
Cdd:cd03269 72 IGYLPEERGLYPKMKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLI 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 641 LDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAG 698
Cdd:cd03269 152 LDEPFSGLDPVNVELLKDVIRElARAGKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
480-693 |
7.44e-35 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 136.09 E-value: 7.44e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKgkpEKVeALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiiNMEEIRN 559
Cdd:PRK13537 7 PIDFRNVEKRYG---DKL-VVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPS--RARHARQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YTGFCPQF-NIYFDFlTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQV 638
Cdd:PRK13537 81 RVGVVPQFdNLDPDF-TVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDV 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 639 LLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGK 693
Cdd:PRK13537 160 LVLDEPTTGLDPQARHLMWERLRSlLARGKTILLTTHFMEEAERLCDRLCVIEEGR 215
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
1305-1508 |
1.50e-34 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 132.26 E-value: 1.50e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPTRqagggfRHLGYCPQEDVLWPD 1381
Cdd:cd03259 13 VRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGrdvTGVPPER------RNIGMVFQDYALFPH 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 LTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQ 1461
Cdd:cd03259 87 LTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLSALDAKLR 166
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1387227070 1462 LQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIG 1508
Cdd:cd03259 167 EELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
1305-1611 |
2.13e-34 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 145.16 E-value: 2.13e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF--RDSGT--PPTRQAgggfrhLGYCPQEDVLWP 1380
Cdd:TIGR01257 943 RPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVggKDIETnlDAVRQS------LGMCPQHNILFH 1016
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 DLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEG 1460
Cdd:TIGR01257 1017 HLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYS 1096
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1461 QLQMWQAIqaIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLKSKFGKDYLLEV--------------- 1525
Cdd:TIGR01257 1097 RRSIWDLL--LKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTPLFLKNCFGTGFYLTLvrkmkniqsqrggce 1174
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1526 ----------------KVKALT------------------------LVEPLHMEILKLFPQAARQERysfvmAYklaied 1565
Cdd:TIGR01257 1175 gtcsctskgfstrcpaRVDEITpeqvldgdvnelmdlvyhhvpeakLVECIGQELIFLLPNKNFKQR-----AY------ 1243
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 1387227070 1566 vhplSQTFSKLEAVKQAFDLEEYSLSQATLEQVFLELSKEQELGNL 1611
Cdd:TIGR01257 1244 ----ASLFRELEETLADLGLSSFGISDTPLEEIFLKVTEDADSGSL 1285
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
484-694 |
2.20e-34 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 131.13 E-value: 2.20e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 484 RNLRKEYKGKPEKVEA--LQGICLDVYEGQLTAILGHSGAGKSSLLSILGG--WSACTEGSATIYNTQLSeiinMEEIRN 559
Cdd:cd03213 7 RNLTVTVKSSPSKSGKqlLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGrrTGLGVSGEVLINGRPLD----KRSFRK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YTGFCPQFNIYFDFLTVRENLRLFAKIKGIppkeveqevksimmeldmhniqdviakelSGGQKRKLTFGIAILGDPQVL 639
Cdd:cd03213 83 IIGYVPQDDILHPTLTVRETLMFAAKLRGL-----------------------------SGGERKRVSIALELVSNPSLL 133
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 640 LLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFST-QFMDEADILADRKVFLSNGKL 694
Cdd:cd03213 134 FLDEPTSGLDSSSALQVMSLLRRlADTGRTIICSIhQPSSEIFELFDKLLLLSQGRV 190
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
481-693 |
3.30e-34 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 131.06 E-value: 3.30e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiiNMEEIRNY 560
Cdd:COG4133 3 LEAENLSCRRGERL----LFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRD--AREDYRRR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEveQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLL 640
Cdd:COG4133 77 LAYLGHADGLKPELTVRENLRFWAALYGLRADR--EAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1387227070 641 LDEPTAGLDPFSRHLVWNFLKERKTNH-TILFSTQfmDEADILADRKVFLSNGK 693
Cdd:COG4133 155 LDEPFTALDAAGVALLAELIAAHLARGgAVLLTTH--QPLELAAARVLDLGDFK 206
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
481-699 |
3.34e-34 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 131.86 E-value: 3.34e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINME--EIR 558
Cdd:cd03261 1 IELRGLTKSFGGRT----VLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAElyRLR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 559 NYTGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVksIMMELDMHNIQDVIAK---ELSGGQKRKLTFGIAILGD 635
Cdd:cd03261 77 RRMGMLFQSGALFDSLTVFENVAFPLREHTRLSEEEIREI--VLEKLEAVGLRGAEDLypaELSGGMKKRVALARALALD 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 636 PQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:cd03261 155 PELLLYDEPTAGLDPIASGVIDDLIRSlkKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGT 220
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
500-646 |
1.67e-33 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 126.99 E-value: 1.67e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 500 LQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIInMEEIRNYTGFCPQFNIYFDFLTVREN 579
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDE-RKSLRKEIGYVFQDPQLFPRLTVREN 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 580 LRLFAKIKGIPPKEVEQEVKSIMMELDM----HNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTA 646
Cdd:pfam00005 80 LRLGLLLKGLSKREKDARAEEALEKLGLgdlaDRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
481-715 |
1.79e-33 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 131.03 E-value: 1.79e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEY-KGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATI--YNTQLSEIINMEEI 557
Cdd:TIGR04521 1 IKLKNVSYIYqPGTPFEKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIdgRDITAKKKKKLKDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 558 RNYTGFCPQFNIYFDF-LTVRE-------NLrlfakikGIPPKEVEQEVKSIMMELDMHniQDVIAK---ELSGGQKRKl 626
Cdd:TIGR04521 81 RKKVGLVFQFPEHQLFeETVYKdiafgpkNL-------GLSEEEAEERVKEALELVGLD--EEYLERspfELSGGQMRR- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 627 tfgIAILG----DPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGSS 700
Cdd:TIGR04521 151 ---VAIAGvlamEPEVLILDEPTAGLDPKGRKEILDLFKRlhKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTP 227
|
250
....*....|....*..
gi 1387227070 701 --LFLKRKWGIGYHLSL 715
Cdd:TIGR04521 228 reVFSDVDELEKIGLDV 244
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
481-693 |
4.68e-33 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 126.34 E-value: 4.68e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEKVeaLQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiINMEEIRNY 560
Cdd:cd03228 1 IEFKNVSFSYPGRPKPV--LKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRD-LDLESLRKN 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFlTVRENLrlfakikgippkeveqevksimmeldmhniqdviakeLSGGQKRKLTFGIAILGDPQVLL 640
Cdd:cd03228 78 IAYVPQDPFLFSG-TIRENI-------------------------------------LSGGQRQRIAIARALLRDPPILI 119
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 641 LDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTQFMDEADiLADRKVFLSNGK 693
Cdd:cd03228 120 LDEATSALDPETEALILEALRALAKGKTVIVIAHRLSTIR-DADRIIVLDDGR 171
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
481-694 |
6.12e-33 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 128.07 E-value: 6.12e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKpekvEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSAC-----TEGSATIYNTQLSEI-INM 554
Cdd:cd03260 1 IELRDLNVYYGDK----HALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLipgapDEGEVLLDGKDIYDLdVDV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 555 EEIRNYTGFCPQFNIYFDfLTVRENLRLFAKIKGIPPKEV-EQEVKSI--MMELDMHNIQDVIAKELSGGQKRKLTFGIA 631
Cdd:cd03260 77 LELRRRVGMVFQKPNPFP-GSIYDNVAYGLRLHGIKLKEElDERVEEAlrKAALWDEVKDRLHALGLSGGQQQRLCLARA 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 632 ILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:cd03260 156 LANEPEVLLLDEPTSALDPISTAKIEELIAELKKEYTIVIVTHNMQQAARVADRTAFLLNGRL 218
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
481-694 |
6.17e-33 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 128.08 E-value: 6.17e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINME--EIR 558
Cdd:cd03258 2 IELKNVSKVFGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKElrKAR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 559 NYTGFCPQ-FNIyFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQ 637
Cdd:cd03258 82 RRIGMIFQhFNL-LSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPK 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 638 VLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:cd03258 161 VLLCDEATSALDPETTQSILALLRDinRELGLTIVLITHEMEVVKRICDRVAVMEKGEV 219
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
1301-1511 |
1.91e-32 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 127.47 E-value: 1.91e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1301 ARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF--RDSGTPPTRQ-AgggfRHLGYCPQEDV 1377
Cdd:COG1120 10 GYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLdgRDLASLSRRElA----RRIAYVPQEPP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1378 LWPDLTVRE--------HLDLYSavkGLTKE--EAALSVSRLADALKLQD-----------QMALPAKALpegAKRklsf 1436
Cdd:COG1120 86 APFGLTVRElvalgrypHLGLFG---RPSAEdrEAVEEALERTGLEHLADrpvdelsggerQRVLIARAL---AQE---- 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 1437 alsvlgsPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQ 1511
Cdd:COG1120 156 -------PPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPE 223
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
1307-1503 |
1.96e-32 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 126.39 E-value: 1.96e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPTRQAGGGfrhLGYCPQEDVLWPDLT 1383
Cdd:cd03224 15 ILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGrdiTGLPPHERARAG---IGYVPEGRRIFPELT 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1384 VREHLDLYSAVKGLTKEEAalsvsRLADAL----KLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPE 1459
Cdd:cd03224 92 VEENLLLGAYARRRAKRKA-----RLERVYelfpRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEPSEGLAPK 166
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1387227070 1460 GQLQMWQAIQAIvksSARGA--LLTTHSMAEAEAVCDRVAIMVSGR 1503
Cdd:cd03224 167 IVEEIFEAIREL---RDEGVtiLLVEQNARFALEIADRAYVLERGR 209
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
480-699 |
2.41e-32 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 126.63 E-value: 2.41e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYN---TQLSEIiNMEE 556
Cdd:COG1127 5 MIEVRNLTKSFGDRV----VLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGqdiTGLSEK-ELYE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 557 IRNYTGFCPQFNIYFDFLTVREN----LRLFakiKGIPPKEVEQEVksiMMELDMHNIQDVIAK---ELSGGQKRKLtfG 629
Cdd:COG1127 80 LRRRIGMLFQGGALFDSLTVFENvafpLREH---TDLSEAEIRELV---LEKLELVGLPGAADKmpsELSGGMRKRV--A 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1387227070 630 IA--ILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:COG1127 152 LAraLALDPEILLYDEPTAGLDPITSAVIDELIRElrDELGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGT 225
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
1305-1504 |
2.75e-32 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 125.70 E-value: 2.75e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPTRqagggFRH-LGYCPQEDVLWP 1380
Cdd:COG4619 13 KPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGkplSAMPPPE-----WRRqVAYVPQEPALWG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 DlTVREHLDLYSAVKGLTKEEAALSvsRLADALKLQ-DQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPE 1459
Cdd:COG4619 88 G-TVRDNLPFPFQLRERKFDRERAL--ELLERLGLPpDILDKPVERLSGGERQRLALIRALLLQPDVLLLDEPTSALDPE 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1387227070 1460 GQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:COG4619 165 NTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
1279-1513 |
3.84e-32 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 126.30 E-value: 3.84e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1279 EPVIMASCLHKEYKqekKRcfsarktkTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SG 1355
Cdd:COG1137 1 MMTLEAENLVKSYG---KR--------TVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGediTH 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1356 TPPTRQAGGGfrhLGYCPQEDVLWPDLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQ---DQMALpakALPEGAKR 1432
Cdd:COG1137 70 LPMHKRARLG---IGYLPQEASIFRKLTVEDNILAVLELRKLSKKEREERLEELLEEFGIThlrKSKAY---SLSGGERR 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1433 KLSFALSVLGSPALLLLDEPTTGMDP----EgqlqmwqaIQAIVKS-SARGA--LLTTHSMAEAEAVCDRVAIMVSGRLR 1505
Cdd:COG1137 144 RVEIARALATNPKFILLDEPFAGVDPiavaD--------IQKIIRHlKERGIgvLITDHNVRETLGICDRAYIISEGKVL 215
|
....*...
gi 1387227070 1506 CIGSVQHL 1513
Cdd:COG1137 216 AEGTPEEI 223
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
481-694 |
6.34e-32 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 124.55 E-value: 6.34e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIinMEEIRNy 560
Cdd:cd03259 1 LELKGLSKTYGSVR----ALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGV--PPERRN- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLL 640
Cdd:cd03259 74 IGMVFQDYALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLL 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 641 LDEPTAGLDPFSR----HLVWNFLKERKTnhTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:cd03259 154 LDEPLSALDAKLReelrEELKELQRELGI--TTIYVTHDQEEALALADRIAVMNEGRI 209
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
476-694 |
1.81e-31 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 123.98 E-value: 1.81e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 476 HRKEAIRIRNLRKEYKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIyntqlseiinME 555
Cdd:cd03267 13 YSKEPGLIGSLKSLFKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRV----------AG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 556 EI--RNYTGFCPQFNIYF--------DfLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRK 625
Cdd:cd03267 83 LVpwKRRKKFLRRIGVVFgqktqlwwD-LPVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMR 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 626 LTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:cd03267 162 AEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEynRERGTTVLLTSHYMKDIEALARRVLVIDKGRL 232
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
481-694 |
1.92e-31 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 123.00 E-value: 1.92e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEkveaLQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRNY 560
Cdd:COG4619 1 LELEGLSFRVGGKPI----LSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAM-PPPEWRRQ 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDfLTVRENLRLFAKIKGIPPKEveQEVKSIMMELDMHNI---QDViaKELSGGQKRKLTFGIAILGDPQ 637
Cdd:COG4619 76 VAYVPQEPALWG-GTVRDNLPFPFQLRERKFDR--ERALELLERLGLPPDildKPV--ERLSGGERQRLALIRALLLQPD 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 638 VLLLDEPTAGLDPFSRHLVWNFLKERKTNH--TILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:COG4619 151 VLLLDEPTSALDPENTRRVEELLREYLAEEgrAVLWVSHDPEQIERVADRVLTLEAGRL 209
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
480-699 |
5.07e-31 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 124.84 E-value: 5.07e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLS-EIINM---- 554
Cdd:COG4152 1 MLELKGLTKRFGDKT----AVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDpEDRRRigyl 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 555 -EEiRnytGFCPQfniyfdfLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAIL 633
Cdd:COG4152 77 pEE-R---GLYPK-------MKVGEQLVYLARLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALL 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 634 GDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTN-HTILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:COG4152 146 HDPELLILDEPFSGLDPVNVELLKDVIRELAAKgTTVIFSSHQMELVEELCDRIVIINKGRKVLSGS 212
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1271-1513 |
5.19e-31 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 129.64 E-value: 5.19e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1271 ALTASSLDEPVIMASCLHKEYKQEKKRcfsarkTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVV 1350
Cdd:COG1123 250 AAPAAAAAEPLLEVRNLSKRYPVRGKG------GVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSIL 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1351 FRdsGTPPTRQAGGGF----RHLGYCPQ--EDVLWPDLTVREH----LDLYsavKGLTKEEAALSVSRLADALKLQDQMA 1420
Cdd:COG1123 324 FD--GKDLTKLSRRSLrelrRRVQMVFQdpYSSLNPRMTVGDIiaepLRLH---GLLSRAERRERVAELLERVGLPPDLA 398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1421 --LPAkALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAI 1498
Cdd:COG1123 399 drYPH-ELSGGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAV 477
|
250
....*....|....*
gi 1387227070 1499 MVSGRLRCIGSVQHL 1513
Cdd:COG1123 478 MYDGRIVEDGPTEEV 492
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
1306-1522 |
6.94e-31 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 132.56 E-value: 6.94e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1306 TAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAG-------VVvfrDSGTPPTRqagggfRHLGYCPQEDVL 1378
Cdd:NF033858 280 TAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGeawlfgqPV---DAGDIATR------RRVGYMSQAFSL 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1379 WPDLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQM-ALPAkALPEGAKRKLSFALSVLGSPALLLLDEPTTGMD 1457
Cdd:NF033858 351 YGELTVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVAdALPD-SLPLGIRQRLSLAVAVIHKPELLILDEPTSGVD 429
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 1458 PEGQLQMWQAIqaIVKSSARGA--LLTTHSMAEAEAvCDRVAIMVSGRLRCIGSVQHLKSKFGKDYL 1522
Cdd:NF033858 430 PVARDMFWRLL--IELSREDGVtiFISTHFMNEAER-CDRISLMHAGRVLASDTPAALVAARGAATL 493
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
1302-1503 |
7.04e-31 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 121.42 E-value: 7.04e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1302 RKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRdsGTPPTRQAGGGFR-HLGYCPQEdvlwP 1380
Cdd:cd03225 11 DGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVD--GKDLTKLSLKELRrKVGLVFQN----P 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 D-----LTVREhlDLYSAVK--GLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFAlSVL-GSPALLLLDEP 1452
Cdd:cd03225 85 DdqffgPTVEE--EVAFGLEnlGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIA-GVLaMDPDILLLDEP 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 1453 TTGMDPEGQLQMWQAIQAIvKSSARGALLTTHSMAEAEAVCDRVAIMVSGR 1503
Cdd:cd03225 162 TAGLDPAGRRELLELLKKL-KAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
1302-1508 |
1.32e-30 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 121.10 E-value: 1.32e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1302 RKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPPTRqAGGGFRhlgycpqedvlwPD 1381
Cdd:cd03220 32 VGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRVSSLLG-LGGGFN------------PE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 LTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQ 1461
Cdd:cd03220 99 LTGRENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDEVLAVGDAAFQ 178
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1387227070 1462 LQMWQAIQAIVKsSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIG 1508
Cdd:cd03220 179 EKCQRRLRELLK-QGKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
1303-1503 |
1.40e-30 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 118.89 E-value: 1.40e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1303 KTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF--RDSGTPPTRQAgggFRHLGYCPQedvlwp 1380
Cdd:cd00267 10 GGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIdgKDIAKLPLEEL---RRRIGYVPQ------ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 dltvrehldlysavkgltkeeaaLSVsrladalklqdqmalpakalpeGAKRKLSFALSVLGSPALLLLDEPTTGMDPEG 1460
Cdd:cd00267 81 -----------------------LSG----------------------GQRQRVALARALLLNPDLLLLDEPTSGLDPAS 115
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1387227070 1461 QLQMWQAIQAIVKsSARGALLTTHSMAEAEAVCDRVAIMVSGR 1503
Cdd:cd00267 116 RERLLELLRELAE-EGRTVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
480-699 |
1.77e-30 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 121.35 E-value: 1.77e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTqlseiiNMEEIRN 559
Cdd:COG1121 6 AIELENLTVSYGGRP----VLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGK------PPRRARR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YTGFCPQ-FNIYFDF-LTVRE--------NLRLFakikGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFG 629
Cdd:COG1121 76 RIGYVPQrAEVDWDFpITVRDvvlmgrygRRGLF----RRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLA 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 630 IAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLsNGKLRCAGS 699
Cdd:COG1121 152 RALAQDPDLLLLDEPFAGVDAATEEALYELLRElRREGKTILVVTHDLGAVREYFDRVLLL-NRGLVAHGP 221
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1304-1509 |
2.46e-30 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 124.05 E-value: 2.46e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1304 TKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPTRqagggfRHLGYCPQEDVLWP 1380
Cdd:COG3842 17 DVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGrdvTGLPPEK------RNVGMVFQDYALFP 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 DLTVREHLdlysA----VKGLTKEEAAlsvSRLADALKL-----------------QDQ-MALpAKALpegAKRklsfal 1438
Cdd:COG3842 91 HLTVAENV----AfglrMRGVPKAEIR---ARVAELLELvglegladryphqlsggQQQrVAL-ARAL---APE------ 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 1439 svlgsPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGS 1509
Cdd:COG3842 154 -----PRVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGT 219
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
481-699 |
2.78e-30 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 121.77 E-value: 2.78e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGkpEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINMEEIRNY 560
Cdd:TIGR04520 1 IEVENVSFSYPE--SEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLDTLDEENLWEIRKK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGfcpqfnIYF---D--FL--TVR-------ENLrlfakikGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKl 626
Cdd:TIGR04520 79 VG------MVFqnpDnqFVgaTVEddvafglENL-------GVPREEMRKRVDEALKLVGMEDFRDREPHLLSGGQKQR- 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 627 tfgIAILG----DPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEAdILADRKVFLSNGKLRCAGS 699
Cdd:TIGR04520 145 ---VAIAGvlamRPDIIILDEATSMLDPKGRKEVLETIRKlnKEEGITVISITHDMEEA-VLADRVIVMNKGKIVAEGT 219
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
480-699 |
4.33e-30 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 127.57 E-value: 4.33e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYkgkPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiINMEEIRN 559
Cdd:COG4988 336 SIELEDVSFSY---PGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSD-LDPASWRR 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YTGFCPQfNIYFDFLTVRENLRLFAkikgipPKEVEQEVKSImmeLDMHNIQDVIAK----------E----LSGGQKRK 625
Cdd:COG4988 412 QIAWVPQ-NPYLFAGTIRENLRLGR------PDASDEELEAA---LEAAGLDEFVAAlpdgldtplgEggrgLSGGQAQR 481
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 626 LTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTQfmDEADI-LADRKVFLSNGKLRCAGS 699
Cdd:COG4988 482 LALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAKGRTVILITH--RLALLaQADRILVLDDGRIVEQGT 554
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
1296-1503 |
5.32e-30 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 119.11 E-value: 5.32e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1296 KRCFSARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRdsGTPPTRQAgggfRHLGYCPQE 1375
Cdd:cd03293 8 KTYGGGGGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVD--GEPVTGPG----PDRGYVFQQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1376 DVLWPDLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQmalpAKALPE----GAKRKLSFALSVLGSPALLLLDE 1451
Cdd:cd03293 82 DALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGF----ENAYPHqlsgGMRQRVALARALAVDPDVLLLDE 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 1452 PTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMvSGR 1503
Cdd:cd03293 158 PFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVL-SAR 208
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
480-699 |
5.50e-30 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 120.53 E-value: 5.50e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRN 559
Cdd:COG1120 1 MLEAENLSVGYGGRP----VLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASL-SRRELAR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YTGFCPQFNIYFDFLTVRENLRL----FAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGD 635
Cdd:COG1120 76 RIAYVPQEPPAPFGLTVRELVALgrypHLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQE 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 636 PQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:COG1120 156 PPLLLLDEPTSHLDLAHQLEVLELLRRlaRERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGP 221
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
491-694 |
1.55e-29 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 118.14 E-value: 1.55e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 491 KGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGG---WSACTEGSATIYNTQLSEiinmEEIRNYTGFCPQF 567
Cdd:cd03234 14 KNWNKYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGrveGGGTTSGQILFNGQPRKP----DQFQKCVAYVRQD 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 568 NIYFDFLTVRENLRLFAKIKG--IPPKEVEQEVKSIMMELDMHN--IQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDE 643
Cdd:cd03234 90 DILLPGLTVRETLTYTAILRLprKSSDAIRKKRVEDVLLRDLALtrIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDE 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1387227070 644 PTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQfMDEADI--LADRKVFLSNGKL 694
Cdd:cd03234 170 PTSGLDSFTALNLVSTLSQlARRNRIVILTIH-QPRSDLfrLFDRILLLSSGEI 222
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
480-699 |
2.94e-29 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 117.83 E-value: 2.94e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINMEeiRN 559
Cdd:cd03296 2 SIEVRNVSKRFGDFV----ALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQE--RN 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 yTGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMEL----DMHNIQDVIAKELSGGQKRKLTFGIAILGD 635
Cdd:cd03296 76 -VGFVFQHYALFRHMTVFDNVAFGLRVKPRSERPPEAEIRAKVHELlklvQLDWLADRYPAQLSGGQRQRVALARALAVE 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 636 PQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:cd03296 155 PKVLLLDEPFGALDAKVRKELRRWLRRlhDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGT 220
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
1310-1508 |
5.79e-29 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 116.24 E-value: 5.79e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1310 NVSFCINkGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDS---------GTPPTRqagggfRHLGYCPQEDVLWP 1380
Cdd:cd03297 16 KIDFDLN-EEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTvlfdsrkkiNLPPQQ------RKIGLVFQQYALFP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 DLTVREHLDLysAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEG 1460
Cdd:cd03297 89 HLNVRENLAF--GLKRKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRAL 166
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1387227070 1461 QLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIG 1508
Cdd:cd03297 167 RLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
1287-1510 |
8.87e-29 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 116.72 E-value: 8.87e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1287 LHKEYKQEKKRCFSARK-----------TKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSG 1355
Cdd:COG1134 10 VSKSYRLYHEPSRSLKElllrrrrtrreEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGRV 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1356 TPPTrQAGGGFRhlgycpqedvlwPDLTVREHLDLYSAVKGLTKEEAAlsvSRLADALK---LQDQMALPAKALPEGAKR 1432
Cdd:COG1134 90 SALL-ELGAGFH------------PELTGRENIYLNGRLLGLSRKEID---EKFDEIVEfaeLGDFIDQPVKTYSSGMRA 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 1433 KLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKsSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSV 1510
Cdd:COG1134 154 RLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLARIRELRE-SGRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDP 230
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
480-713 |
1.38e-28 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 122.95 E-value: 1.38e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGKPEKVeaLQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRN 559
Cdd:COG4987 333 SLELEDVSFRYPGAGRPV--LDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDL-DEDDLRR 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YTGFCPQ----FNIyfdflTVRENLRLfAKikgipPKEVEQEVKSImmeLDMHNIQDVIAKE--------------LSGG 621
Cdd:COG4987 410 RIAVVPQrphlFDT-----TLRENLRL-AR-----PDATDEELWAA---LERVGLGDWLAALpdgldtwlgeggrrLSGG 475
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 622 QKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTQFMDEADiLADRKVFLSNGKLRCAGSSL 701
Cdd:COG4987 476 ERRRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEALAGRTVLLITHRLAGLE-RMDRILVLEDGRIVEQGTHE 554
|
250
....*....|..
gi 1387227070 702 FLKRKWGIGYHL 713
Cdd:COG4987 555 ELLAQNGRYRQL 566
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
480-699 |
2.28e-28 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 121.55 E-value: 2.28e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGKPekVEALQGICLDVYEGQLTAILGHSGAGKSSL-LSILG--GWSACTEGSATIYNTQLSEIiNMEE 556
Cdd:COG1123 4 LLEVRDLSVRYPGGD--VPAVDGVSLTIAPGETVALVGESGSGKSTLaLALMGllPHGGRISGEVLLDGRDLLEL-SEAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 557 IRNYTGFCPQ-FNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGD 635
Cdd:COG1123 81 RGRRIGMVFQdPMTQLNPVTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALD 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 636 PQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:COG1123 161 PDLLIADEPTTALDVTTQAEILDLLRElqRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGP 226
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
481-694 |
2.39e-28 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 115.09 E-value: 2.39e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEkveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRNY 560
Cdd:cd03295 1 IEFENVTKRYGGGKK---AVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQ-DPVELRRK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSI--MMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQV 638
Cdd:cd03295 77 IGYVIQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELlaLVGLDPAEFADRYPHELSGGQQQRVGVARALAADPPL 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 639 LLLDEPTAGLDPFSR-HLVWNFLK-ERKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:cd03295 157 LLMDEPFGALDPITRdQLQEEFKRlQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEI 214
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
1307-1515 |
3.24e-28 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 114.69 E-value: 3.24e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPTRQAGGGfrhLGYCPQEDVLWPDLT 1383
Cdd:COG0410 18 VLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGediTGLPPHRIARLG---IGYVPEGRRIFPSLT 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1384 VREHLDLYSAVKGLTKEEAAlsvsRLADAL----KLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPE 1459
Cdd:COG0410 95 VEENLLLGAYARRDRAEVRA----DLERVYelfpRLKERRRQRAGTLSGGEQQMLAIGRALMSRPKLLLLDEPSLGLAPL 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 1460 GQLQMWQAIQAIvksSARGA--LLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLKS 1515
Cdd:COG0410 171 IVEEIFEIIRRL---NREGVtiLLVEQNARFALEIADRAYVLERGRIVLEGTAAELLA 225
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1301-1513 |
4.11e-28 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 120.78 E-value: 4.11e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1301 ARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTA---GVVVF--RDSGTPPTRQAGggfRHLGYCPQE 1375
Cdd:COG1123 15 PGGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGGrisGEVLLdgRDLLELSEALRG---RRIGMVFQD 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1376 --DVLWPdLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPT 1453
Cdd:COG1123 92 pmTQLNP-VTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPDLLIADEPT 170
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1454 TGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHL 1513
Cdd:COG1123 171 TALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEI 230
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
1302-1504 |
4.49e-28 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 114.14 E-value: 4.49e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1302 RKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF--RDSGTPPTRQAGGGFRHLGYCPQE--DV 1377
Cdd:cd03257 15 GGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFdgKDLLKLSRRLRKIRRKEIQMVFQDpmSS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1378 LWPDLTVREHL-DLYSAVKGLTKEEAalsvsRLADALKLQDQMALPAKAL---PE----GAKRKLSFALSVLGSPALLLL 1449
Cdd:cd03257 95 LNPRMTIGEQIaEPLRIHGKLSKKEA-----RKEAVLLLLVGVGLPEEVLnryPHelsgGQRQRVAIARALALNPKLLIA 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 1450 DEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:cd03257 170 DEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKI 224
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
481-699 |
7.63e-28 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 113.69 E-value: 7.63e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGkpekVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSAtIYN----TQLS--EIINM 554
Cdd:cd03219 1 LEVRGLTKRFGG----LVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSV-LFDgediTGLPphEIARL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 555 eeirnytGFCPQF---NIYFDfLTVRENLRLFAKIKGIPP----------KEVEQEVKSIMMELDMHNIQDVIAKELSGG 621
Cdd:cd03219 76 -------GIGRTFqipRLFPE-LTVLENVMVAAQARTGSGlllararreeREARERAEELLERVGLADLADRPAGELSYG 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 622 QKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILfstqfMDEADI-----LADRKVFLSNGKLR 695
Cdd:cd03219 148 QQRRLEIARALATDPKLLLLDEPAAGLNPEETEELAELIRElRERGITVL-----LVEHDMdvvmsLADRVTVLDQGRVI 222
|
....
gi 1387227070 696 CAGS 699
Cdd:cd03219 223 AEGT 226
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1276-1503 |
7.65e-28 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 114.42 E-value: 7.65e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1276 SLDEPVIMASCLHKEYKqekkrcfSARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRdsG 1355
Cdd:COG1116 2 SAAAPALELRGVSKRFP-------TGGGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVD--G 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1356 TPPTrqagGGFRHLGYCPQEDVLWPDLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQM-ALPaKALPEGAKRKL 1434
Cdd:COG1116 73 KPVT----GPGPDRGVVFQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEdAYP-HQLSGGMRQRV 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 1435 SFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMvSGR 1503
Cdd:COG1116 148 AIARALANDPEVLLMDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHDVDEAVFLADRVVVL-SAR 215
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
481-694 |
8.31e-28 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 112.62 E-value: 8.31e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKpekvEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLS-EIINMEEIRN 559
Cdd:cd03262 1 IEIKNLHKSFGDF----HVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTdDKKNINELRQ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YTGFCPQ-FNIyFDFLTVRENLRL-FAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQ 637
Cdd:cd03262 77 KVGMVFQqFNL-FPHLTVLENITLaPIKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPK 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 638 VLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:cd03262 156 VMLFDEPTSALDPELVGEVLDVMKDlAEEGMTMVVVTHEMGFAREVADRVIFMDDGRI 213
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
481-700 |
9.11e-28 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 112.91 E-value: 9.11e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKgkpeKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINMEEIRNY 560
Cdd:cd03224 1 LEVENLNAGYG----KSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERARAG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFLTVRENLRLFAKIKgiPPKEVEQEVKSImmeLDM----HNIQDVIAKELSGGQKRKLTFGIAILGDP 636
Cdd:cd03224 77 IGYVPEGRRIFPELTVEENLLLGAYAR--RRAKRKARLERV---YELfprlKERRKQLAGTLSGGEQQMLAIARALMSRP 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 637 QVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGSS 700
Cdd:cd03224 152 KLLLLDEPSEGLAPKIVEEIFEAIRElRDEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTA 216
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
481-694 |
2.45e-27 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 111.83 E-value: 2.45e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIIN--MEEIR 558
Cdd:cd03257 2 LEVKNLSVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRrlRKIRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 559 NYTGFCPQ-----FNIYFdflTVRENLRLFAKIKGIPPKEVEQEVKsIMMELDMHNIQDVIAK----ELSGGQKRKLTFG 629
Cdd:cd03257 82 KEIQMVFQdpmssLNPRM---TIGEQIAEPLRIHGKLSKKEARKEA-VLLLLVGVGLPEEVLNryphELSGGQRQRVAIA 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 630 IAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:cd03257 158 RALALNPKLLIADEPTSALDVSVQAQILDLLKKlqEELGLTLLFITHDLGVVAKIADRVAVMYAGKI 224
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
481-693 |
2.72e-27 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 109.97 E-value: 2.72e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQL-SEIINMEEIRN 559
Cdd:cd03229 1 LELKNVSKRYGQKT----VLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLtDLEDELPPLRR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YTGFCPQFNIYFDFLTVRENLRLfakikgippkeveqevksimmeldmhniqdviakELSGGQKRKLTFGIAILGDPQVL 639
Cdd:cd03229 77 RIGMVFQDFALFPHLTVLENIAL----------------------------------GLSGGQQQRVALARALAMDPDVL 122
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 640 LLDEPTAGLDPFSRHLVWNFLKERKTNH--TILFSTQFMDEADILADRKVFLSNGK 693
Cdd:cd03229 123 LLDEPTSALDPITRREVRALLKSLQAQLgiTVVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
1287-1504 |
2.73e-27 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 111.43 E-value: 2.73e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1287 LHKEYKQEKKRcfsarktKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTRQAGGG- 1365
Cdd:cd03255 6 LSKTYGGGGEK-------VQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRV--DGTDISKLSEKEl 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1366 --FR--HLGYCPQEDVLWPDLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVL 1441
Cdd:cd03255 77 aaFRrrHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALA 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 1442 GSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAvCDRVAIMVSGRL 1504
Cdd:cd03255 157 NDPKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELAEY-ADRIIELRDGKI 218
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
480-694 |
5.42e-27 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 114.42 E-value: 5.42e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIInMEEiRN 559
Cdd:COG3842 5 ALELENVSKRYGDVT----ALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLP-PEK-RN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 yTGFCPQfNiY--FDFLTVRENLRLFAKIKGIPPKEVEQEVKSImmeLDMHNIQDVIAK---ELSGGQK------Rkltf 628
Cdd:COG3842 79 -VGMVFQ-D-YalFPHLTVAENVAFGLRMRGVPKAEIRARVAEL---LELVGLEGLADRyphQLSGGQQqrvalaR---- 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 629 giAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFST--QfmDEADILADRKVFLSNGKL 694
Cdd:COG3842 149 --ALAPEPRVLLLDEPLSALDAKLREEMREELRRlqRELGITFIYVThdQ--EEALALADRIAVMNDGRI 214
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
481-694 |
7.54e-27 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 110.14 E-value: 7.54e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYkgkPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiINMEEI--- 557
Cdd:COG2884 2 IRFENVSKRY---PGGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSR-LKRREIpyl 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 558 RNYTGFCPQfniyfDF-----LTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLtfGI-- 630
Cdd:COG2884 78 RRRIGVVFQ-----DFrllpdRTVYENVALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRV--AIar 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 631 AILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFST---QFMDEadiLADRKVFLSNGKL 694
Cdd:COG2884 151 ALVNRPELLLADEPTGNLDPETSWEIMELLEEiNRRGTTVLIAThdlELVDR---MPKRVLELEDGRL 215
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
480-699 |
7.87e-27 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 114.01 E-value: 7.87e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGkpekVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGsaTIYntqlseiINMEEI-- 557
Cdd:COG3839 3 SLELENVSKSYGG----VEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSG--EIL-------IGGRDVtd 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 558 -----RNyTGFCPQFNIYFDFLTVRENLrLFA-KIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIA 631
Cdd:COG3839 70 lppkdRN-IAMVFQSYALYPHMTVYENI-AFPlKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRA 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 632 ILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:COG3839 148 LVREPKVFLLDEPLSNLDAKLRVEMRAEIKRlhRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGT 217
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
477-699 |
1.09e-26 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 111.24 E-value: 1.09e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 477 RKEAIRIRNLRKEYKgkPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiINMEE 556
Cdd:PRK13632 4 KSVMIKVENVSFSYP--NSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISK-ENLKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 557 IRNYTGFCPQfNIYFDFL--TVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILG 634
Cdd:PRK13632 81 IRKKIGIIFQ-NPDNQFIgaTVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLAL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 635 DPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEAdILADRKVFLSNGKLRCAGS 699
Cdd:PRK13632 160 NPEIIIFDESTSMLDPKGKREIKKIMVDlrKTRKKTLISITHDMDEA-ILADKVIVFSEGKLIAQGK 225
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
481-694 |
1.17e-26 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 113.32 E-value: 1.17e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATI----YNTQLS--Eiinm 554
Cdd:COG1118 3 IEVRNISKRFGSFT----LLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLngrdLFTNLPprE---- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 555 eeiRNyTGFCPQfNiY--FDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQK------RKL 626
Cdd:COG1118 75 ---RR-VGFVFQ-H-YalFPHMTVAENIAFGLRVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRqrvalaRAL 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 627 tfgiAIlgDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:COG1118 149 ----AV--EPEVLLLDEPFGALDAKVRKELRRWLRRlhDELGGTTVFVTHDQEEALELADRVVVMNQGRI 212
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
1301-1484 |
1.20e-26 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 108.99 E-value: 1.20e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1301 ARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTRQAGGGFRHLGYCPQEDVLWP 1380
Cdd:TIGR01189 9 SRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRW--NGTPLAEQRDEPHENILYLGHLPGLKP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 DLTVREHLDLYSAVKGltkeEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEG 1460
Cdd:TIGR01189 87 ELSALENLHFWAAIHG----GAQRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKAG 162
|
170 180
....*....|....*....|....*.
gi 1387227070 1461 QLQMWQAIQAivkSSARG--ALLTTH 1484
Cdd:TIGR01189 163 VALLAGLLRA---HLARGgiVLLTTH 185
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1305-1512 |
1.50e-26 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 110.18 E-value: 1.50e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTRQAgggfRHLGYCPQ-EDVLW--Pd 1381
Cdd:COG1121 19 RPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRL--FGKPPRRAR----RRIGYVPQrAEVDWdfP- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 LTVRE--------HLdlySAVKGLTKEEAAlsvsRLADALK---LQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLD 1450
Cdd:COG1121 92 ITVRDvvlmgrygRR---GLFRRPSRADRE----AVDEALErvgLEDLADRPIGELSGGQQQRVLLARALAQDPDLLLLD 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 1451 EPTTGMDPEGQlqmwQAIQAIVKS-SARGA--LLTTHSMAEAEAVCDRVaIMVSGRLRCIGSVQH 1512
Cdd:COG1121 165 EPFAGVDAATE----EALYELLRElRREGKtiLVVTHDLGAVREYFDRV-LLLNRGLVAHGPPEE 224
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
1305-1503 |
1.57e-26 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 108.04 E-value: 1.57e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPPTRQAGGGFR-HLGYCPQEDVLWPDLT 1383
Cdd:cd03229 13 KTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDELPPLRrRIGMVFQDFALFPHLT 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1384 VREHLDLysavkgltkeeaalsvsrladalklqdqmalpakALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQ 1463
Cdd:cd03229 93 VLENIAL----------------------------------GLSGGQQQRVALARALAMDPDVLLLDEPTSALDPITRRE 138
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1387227070 1464 MWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGR 1503
Cdd:cd03229 139 VRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
458-713 |
2.10e-26 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 117.24 E-value: 2.10e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 458 MNSELSCDDSFEPVSPEfHRKEAIRIRNLRKEYKGKPEKVeaLQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACT 537
Cdd:COG2274 452 LDLPPEREEGRSKLSLP-RLKGDIELENVSFRYPGDSPPV--LDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPT 528
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 538 EGSATIYNTQLSEIiNMEEIRNYTGFCPQfNIYFDFLTVRENLRLFAKikGIPPKEVEQEvksimmeLDMHNIQDVIAK- 616
Cdd:COG2274 529 SGRILIDGIDLRQI-DPASLRRQIGVVLQ-DVFLFSGTIRENITLGDP--DATDEEIIEA-------ARLAGLHDFIEAl 597
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 617 -------------ELSGGQKRKLtfGIA--ILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTQfmDEADI 681
Cdd:COG2274 598 pmgydtvvgeggsNLSGGQRQRL--AIAraLLRNPRILILDEATSALDAETEAIILENLRRLLKGRTVIIIAH--RLSTI 673
|
250 260 270
....*....|....*....|....*....|...
gi 1387227070 682 -LADRKVFLSNGKLRCAGSSLFLKRKWGIGYHL 713
Cdd:COG2274 674 rLADRIIVLDKGRIVEDGTHEELLARKGLYAEL 706
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
480-694 |
2.26e-26 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 109.89 E-value: 2.26e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINMEEIRN 559
Cdd:COG1124 1 MLEVRNLSVSYGQGGRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRKAFRRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 --------YTGFCPQFniyfdflTVRENLRLFAKIKGIPpkEVEQEVKSIMMELDMH-NIQDVIAKELSGGQKRKLTFGI 630
Cdd:COG1124 81 vqmvfqdpYASLHPRH-------TVDRILAEPLRIHGLP--DREERIAELLEQVGLPpSFLDRYPHQLSGGQRQRVAIAR 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 631 AILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:COG1124 152 ALILEPELLLLDEPTSALDVSVQAEILNLLKDlrEERGLTYLFVSHDLAVVAHLCDRVAVMQNGRI 217
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
481-693 |
3.42e-26 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 110.52 E-value: 3.42e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEY-KGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQL-SEIINMEEIR 558
Cdd:PRK13637 3 IKIENLTHIYmEGTPFEKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDItDKKVKLSDIR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 559 NYTGFCPQFNIYFDFL-TVRENLRLFAKIKGIPPKEVEQEVKSIM--MELDMHNIQDVIAKELSGGQKRKltfgIAILG- 634
Cdd:PRK13637 83 KKVGLVFQYPEYQLFEeTIEKDIAFGPINLGLSEEEIENRVKRAMniVGLDYEDYKDKSPFELSGGQKRR----VAIAGv 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1387227070 635 ---DPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGK 693
Cdd:PRK13637 159 vamEPKILILDEPTAGLDPKGRDEILNKIKElhKEYNMTIILVSHSMEDVAKLADRIIVMNKGK 222
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
480-731 |
3.44e-26 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 111.33 E-value: 3.44e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYK------G---------KPEK--VEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSAT 542
Cdd:COG4586 1 IIEVENLSKTYRvyekepGlkgalkglfRREYreVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 543 IyntqLSEIINMEEIRNytgfcpQFNI----------YFDfLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQD 612
Cdd:COG4586 81 V----LGYVPFKRRKEF------ARRIgvvfgqrsqlWWD-LPAIDSFRLLKAIYRIPDAEYKKRLDELVELLDLGELLD 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 613 VIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDeaDI--LADRKVF 688
Cdd:COG4586 150 TPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEynRERGTTILLTSHDMD--DIeaLCDRVIV 227
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 1387227070 689 LSNGKLRCAGSSLFLKRKWGIGYHLSLHRNERCNTERITSLIT 731
Cdd:COG4586 228 IDHGRIIYDGSLEELKERFGPYKTIVLELAEPVPPLELPRGGE 270
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
481-699 |
3.77e-26 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 108.48 E-value: 3.77e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEI------INM 554
Cdd:cd03300 1 IELENVSKFYGGFV----ALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLpphkrpVNT 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 555 eeirnytgfcpQFNIY--FDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAI 632
Cdd:cd03300 77 -----------VFQNYalFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARAL 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 633 LGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:cd03300 146 VNEPKVLLLDEPLGALDLKLRKDMQLELKRlqKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGT 214
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
480-694 |
4.20e-26 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 108.99 E-value: 4.20e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGKpekVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINME--EI 557
Cdd:COG3638 2 MLELRNLSKRYPGG---TPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRGRAlrRL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 558 RNYTGFCPQ-FNIyFDFLTVREN--------LRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLtf 628
Cdd:COG3638 79 RRRIGMIFQqFNL-VPRLSVLTNvlagrlgrTSTWRSLLGLFPPEDRERALEALERVGLADKAYQRADQLSGGQQQRV-- 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 629 GIA--ILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:COG3638 156 AIAraLVQEPKLILADEPVASLDPKTARQVMDLLRRiaREDGITVVVNLHQVDLARRYADRIIGLRDGRV 225
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
482-694 |
5.81e-26 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 107.34 E-value: 5.81e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 482 RIRNLRKEYKGKPEkveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNtqlsEIINMEEIRNYT 561
Cdd:cd03226 1 RIENISFSYKKGTE---ILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNG----KPIKAKERRKSI 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 562 GFCPQ---FNIYFDflTVRENLRLFAKIKGIPPKEVEQevksIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQV 638
Cdd:cd03226 74 GYVMQdvdYQLFTD--SVREELLLGLKELDAGNEQAET----VLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDL 147
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 639 LLLDEPTAGLDPFSRHLVWN-FLKERKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:cd03226 148 LIFDEPTSGLDYKNMERVGElIRELAAQGKAVIVITHDYEFLAKVCDRVLLLANGAI 204
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
479-695 |
1.39e-25 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 108.03 E-value: 1.39e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 479 EAIRIRNLRKEYKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIyntqlseiiNMEEIr 558
Cdd:COG4525 2 SMLTVRHVSVRYPGGGQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITL---------DGVPV- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 559 nyTG--------FcpQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLtfGI 630
Cdd:COG4525 72 --TGpgadrgvvF--QKDALLPWLNVLDNVAFGLRLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRV--GI 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1387227070 631 A--ILGDPQVLLLDEPTAGLDPFSR-----HL--VWnflkeRKTNHTILFSTQFMDEADILADRKVFLSNGKLR 695
Cdd:COG4525 146 AraLAADPRFLLMDEPFGALDALTReqmqeLLldVW-----QRTGKGVFLITHSVEEALFLATRLVVMSPGPGR 214
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
481-694 |
1.58e-25 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 109.78 E-value: 1.58e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYN---TQLSEiinmEEI 557
Cdd:COG1135 2 IELENLSKTFPTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGvdlTALSE----REL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 558 RNY---TGFCPQ-FNIyFDFLTVRENLRLFAKIKGIPPKEVEQEVKSImmeLDMHNIQDVIAK---ELSGGQKRKLtfGI 630
Cdd:COG1135 78 RAArrkIGMIFQhFNL-LSSRTVAENVALPLEIAGVPKAEIRKRVAEL---LELVGLSDKADAypsQLSGGQKQRV--GI 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 631 A--ILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:COG1135 152 AraLANNPKVLLCDEATSALDPETTRSILDLLKDinRELGLTIVLITHEMDVVRRICDRVAVLENGRI 219
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
481-700 |
1.61e-25 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 112.69 E-value: 1.61e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGK-PEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEII--NMEEI 557
Cdd:COG1123 261 LEVRNLSKRYPVRgKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSrrSLREL 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 558 RNYTGFCPQ-----FNiyfDFLTVRENLRLFAKIKGI-PPKEVEQEVKSIM--MELDmhniQDVIAK---ELSGGQKRKL 626
Cdd:COG1123 341 RRRVQMVFQdpyssLN---PRMTVGDIIAEPLRLHGLlSRAERRERVAELLerVGLP----PDLADRyphELSGGQRQRV 413
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 627 TFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGSS 700
Cdd:COG1123 414 AIARALALEPKLLILDEPTSALDVSVQAQILNLLRDlqRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPT 489
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
481-695 |
1.91e-25 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 105.80 E-value: 1.91e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKgkpeKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGsaTIYntqlseiINMEEI--- 557
Cdd:cd03301 1 VELENVTKRFG----NVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSG--RIY-------IGGRDVtdl 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 558 ----RNYTGFCPQFNIYfDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAIL 633
Cdd:cd03301 68 ppkdRDIAMVFQNYALY-PHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIV 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1387227070 634 GDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKLR 695
Cdd:cd03301 147 REPKVFLMDEPLSNLDAKLRVQMRAELKRlqQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQ 210
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
482-698 |
3.46e-25 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 105.31 E-value: 3.46e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 482 RIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLseiinmEEIRNYT 561
Cdd:cd03235 1 EVEDLTVSYGGHP----VLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPL------EKERKRI 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 562 GFCPQ-FNIYFDF-LTVRE--NLRLFAKIK--GIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGD 635
Cdd:cd03235 71 GYVPQrRSIDRDFpISVRDvvLMGLYGHKGlfRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQD 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1387227070 636 PQVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRkVFLSNGKLRCAG 698
Cdd:cd03235 151 PDLLLLDEPFAGVDPKTQEDIYELLRElRREGMTILVVTHDLGLVLEYFDR-VLLLNRTVVASG 213
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
1303-1508 |
4.81e-25 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 104.64 E-value: 4.81e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1303 KTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPTRqagggfRHLGYCPQEDVLW 1379
Cdd:cd03301 11 GNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGrdvTDLPPKD------RDIAMVFQNYALY 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1380 PDLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPE 1459
Cdd:cd03301 85 PHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLSNLDAK 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1387227070 1460 GQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIG 1508
Cdd:cd03301 165 LRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
473-698 |
4.85e-25 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 105.31 E-value: 4.85e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 473 PEFHRKEAIRIRNLRKEYKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIyNTQLSEII 552
Cdd:cd03220 11 PTYKGGSSSLKKLGILGRKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTV-RGRVSSLL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 553 NMEeirnyTGFCPQfniyfdfLTVRENLRLFAKIKGIPPKEVEQEVKSImmeLDMHNIQDVI---AKELSGGQKRKLTFG 629
Cdd:cd03220 90 GLG-----GGFNPE-------LTGRENIYLNGRLLGLSRKEIDEKIDEI---IEFSELGDFIdlpVKTYSSGMKARLAFA 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 630 IAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNH-TILFSTQFMDEADILADRKVFLSNGKLRCAG 698
Cdd:cd03220 155 IATALEPDILLIDEVLAVGDAAFQEKCQRRLRELLKQGkTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
496-700 |
6.75e-25 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 105.06 E-value: 6.75e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 496 KVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATiYNTQlsEIINM--EEI-RNYTGFCPQF-NIyF 571
Cdd:COG0410 15 GIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIR-FDGE--DITGLppHRIaRLGIGYVPEGrRI-F 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 572 DFLTVRENLRLFAKIKgiPPKEVEQEVKSIMMEL--DMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLD 649
Cdd:COG0410 91 PSLTVEENLLLGAYAR--RDRAEVRADLERVYELfpRLKERRRQRAGTLSGGEQQMLAIGRALMSRPKLLLLDEPSLGLA 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 650 PFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGSS 700
Cdd:COG0410 169 PLIVEEIFEIIRRlNREGVTILLVEQNARFALEIADRAYVLERGRIVLEGTA 220
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
481-693 |
1.02e-24 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 104.57 E-value: 1.02e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYkgkPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINMEE--IR 558
Cdd:cd03256 1 IEVENLSKTY---PNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKALrqLR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 559 NYTGFCPQ-FNIyFDFLTVRENL---RL-----FAKIKGIPPKEVEQEVKSIMME---LDMHNIQdviAKELSGGQKRKL 626
Cdd:cd03256 78 RQIGMIFQqFNL-IERLSVLENVlsgRLgrrstWRSLFGLFPKEEKQRALAALERvglLDKAYQR---ADQLSGGQQQRV 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 627 tfGIA--ILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGK 693
Cdd:cd03256 154 --AIAraLMQQPKLILADEPVASLDPASSRQVMDLLKRinREEGITVIVSLHQVDLAREYADRIVGLKDGR 222
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
1301-1509 |
1.17e-24 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 104.59 E-value: 1.17e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1301 ARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPPTRQAGGGFRHLGYCPQEDVLWP 1380
Cdd:PRK10895 12 AYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHARARRGIGYLPQEASIFR 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 DLTVREHL-DLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPE 1459
Cdd:PRK10895 92 RLSVYDNLmAVLQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDPI 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1460 GQLQMWQAIQAIvKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGS 1509
Cdd:PRK10895 172 SVIDIKRIIEHL-RDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGT 220
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
1305-1508 |
1.58e-24 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 103.38 E-value: 1.58e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVV-VFrdsGTPPTRQAgggfRHLGYCPQ-EDVLW--P 1380
Cdd:cd03235 12 HPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIrVF---GKPLEKER----KRIGYVPQrRSIDRdfP 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 dLTVRE--HLDLYSAV---KGLTKEEAAlsvsRLADALKLQDQMALPAKALPE---GAKRKLSFALSVLGSPALLLLDEP 1452
Cdd:cd03235 85 -ISVRDvvLMGLYGHKglfRRLSKADKA----KVDEALERVGLSELADRQIGElsgGQQQRVLLARALVQDPDLLLLDEP 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 1453 TTGMDPEGQLQMWQAIQAiVKSSARGALLTTHSMAEAEAVCDRVaIMVSGRLRCIG 1508
Cdd:cd03235 160 FAGVDPKTQEDIYELLRE-LRREGMTILVVTHDLGLVLEYFDRV-LLLNRTVVASG 213
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
481-694 |
1.75e-24 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 103.26 E-value: 1.75e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYkgkPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIIN--MEEIR 558
Cdd:cd03292 1 IEFINVTKTY---PNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGraIPYLR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 559 NYTGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQV 638
Cdd:cd03292 78 RKIGVVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTI 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 639 LLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:cd03292 158 LIADEPTGNLDPDTTWEIMNLLKKiNKAGTTVVVATHAKELVDTTRHRVIALERGKL 214
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
482-698 |
2.26e-24 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 101.74 E-value: 2.26e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 482 RIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIinmeeirnyt 561
Cdd:cd03214 1 EVENLSVGYGGRT----VLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASL---------- 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 562 gfcpqfniyfdfltvreNLRLFAKIKGIppkeVEQevksIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLL 641
Cdd:cd03214 67 -----------------SPKELARKIAY----VPQ----ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLL 121
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 642 DEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAG 698
Cdd:cd03214 122 DEPTSHLDIAHQIELLELLRRlaRERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
478-699 |
2.66e-24 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 104.78 E-value: 2.66e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 478 KEAIRIRNLRKEYKGKPEKVE--ALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINME 555
Cdd:PRK13633 2 NEMIKCKNVSYKYESNEESTEklALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEENLW 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 556 EIRNYTGFC---PQFNIYFDFltVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKltfgIAI 632
Cdd:PRK13633 82 DIRNKAGMVfqnPDNQIVATI--VEEDVAFGPENLGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQR----VAI 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 633 LG----DPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEAdILADRKVFLSNGKLRCAGS 699
Cdd:PRK13633 156 AGilamRPECIIFDEPTAMLDPSGRREVVNTIKElnKKYGITIILITHYMEEA-VEADRIIVMDSGKVVMEGT 227
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
509-698 |
3.03e-24 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 102.37 E-value: 3.03e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 509 EGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQL--SEI-INMEEIRNYTGFCPQFNIYFDFLTVRENLrLFAk 585
Cdd:cd03297 22 NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLfdSRKkINLPPQQRKIGLVFQQYALFPHLNVRENL-AFG- 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 586 IKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKT 665
Cdd:cd03297 100 LKRKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLPELKQIKK 179
|
170 180 190
....*....|....*....|....*....|....*
gi 1387227070 666 NHTI--LFSTQFMDEADILADRKVFLSNGKLRCAG 698
Cdd:cd03297 180 NLNIpvIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
|
|
| urea_trans_UrtE |
TIGR03410 |
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ... |
482-692 |
3.08e-24 |
|
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 102.99 E-value: 3.08e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 482 RIRNLRKEYKGKpekvEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINMEEIRNYT 561
Cdd:TIGR03410 2 EVSNLNVYYGQS----HILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHERARAGI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 562 GFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMEL-DMHNIQdviAKELSGGQKRKLTFGIAILGDPQVLL 640
Cdd:TIGR03410 78 AYVPQGREIFPRLTVEENLLTGLAALPRRSRKIPDEIYELFPVLkEMLGRR---GGDLSGGQQQQLAIARALVTRPKLLL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 641 LDEPTAGLDPfS----RHLVWNFLKERKtNHTILFSTQFMDEADILADRKVFLSNG 692
Cdd:TIGR03410 155 LDEPTEGIQP-SiikdIGRVIRRLRAEG-GMAILLVEQYLDFARELADRYYVMERG 208
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
481-700 |
3.91e-24 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 102.62 E-value: 3.91e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSatIYntqlseiINMEEIRNY 560
Cdd:cd03218 1 LRAENLSKRYGKRK----VVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGK--IL-------LDGQDITKL 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 T---------GFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIA 631
Cdd:cd03218 68 PmhkrarlgiGYLPQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARA 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 632 ILGDPQVLLLDEPTAGLDPFS----RHLVwNFLKERK-----TNHTIlfstqfmDEADILADRKVFLSNGKLRCAGSS 700
Cdd:cd03218 148 LATNPKFLLLDEPFAGVDPIAvqdiQKII-KILKDRGigvliTDHNV-------RETLSITDRAYIIYEGKVLAEGTP 217
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
1305-1508 |
4.43e-24 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 100.97 E-value: 4.43e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF--RDSGTPPTRQAGggfRHLGYCPQedvlwpdl 1382
Cdd:cd03214 12 RTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLdgKDLASLSPKELA---RKIAYVPQ-------- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1383 tvrehldlysavkgltkeeaalsVSRLADALKLQDQmalPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQL 1462
Cdd:cd03214 81 -----------------------ALELLGLAHLADR---PFNELSGGERQRVLLARALAQEPPILLLDEPTSHLDIAHQI 134
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1387227070 1463 QMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIG 1508
Cdd:cd03214 135 ELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
1299-1504 |
7.36e-24 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 100.70 E-value: 7.36e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1299 FSARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTA--GVVVFrdSGTPPTRQAGGgfRHLGYCPQED 1376
Cdd:cd03213 16 SPSKSGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGLGvsGEVLI--NGRPLDKRSFR--KIIGYVPQDD 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1377 VLWPDLTVREHLDlYSAvkgltkeeaalsvsrladalKLqdqmalpaKALPEGAKRKLSFALSVLGSPALLLLDEPTTGM 1456
Cdd:cd03213 92 ILHPTLTVRETLM-FAA--------------------KL--------RGLSGGERKRVSIALELVSNPSLLFLDEPTSGL 142
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1387227070 1457 DPEGQLQMWQAIQAIVKSSaRGALLTTHS-MAEAEAVCDRVAIMVSGRL 1504
Cdd:cd03213 143 DSSSALQVMSLLRRLADTG-RTIICSIHQpSSEIFELFDKLLLLSQGRV 190
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
481-694 |
7.87e-24 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 102.38 E-value: 7.87e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYkgkPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINME--EIR 558
Cdd:TIGR02315 2 LEVENLSKVY---PNGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLRGKKlrKLR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 559 NYTGFCPQ-FNIyFDFLTVRENL---RLFAK--IKGIP---PKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFG 629
Cdd:TIGR02315 79 RRIGMIFQhYNL-IERLTVLENVlhgRLGYKptWRSLLgrfSEEDKERALSALERVGLADKAYQRADQLSGGQQQRVAIA 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 630 IAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:TIGR02315 158 RALAQQPDLILADEPIASLDPKTSKQVMDYLKRinKEDGITVIINLHQVDLAKKYADRIVGLKAGEI 224
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
1287-1513 |
8.38e-24 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 101.89 E-value: 8.38e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1287 LHKEYKQekkrcfsARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTRQAGGGF 1366
Cdd:cd03258 7 VSKVFGD-------TGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLV--DGTDLTLLSGKEL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1367 R----HLGYCPQEDVLWPDLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQmalpAKALPE----GAKRKLSFAL 1438
Cdd:cd03258 78 RkarrRIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDK----ADAYPAqlsgGQKQRVGIAR 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 1439 SVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHL 1513
Cdd:cd03258 154 ALANNPKVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEV 228
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
505-698 |
8.60e-24 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 101.03 E-value: 8.60e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 505 LDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTqlsEIINMEEIRNYTGFCPQFNIYFDFLTVRENLRLfA 584
Cdd:cd03298 19 LTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGV---DVTAAPPADRPVSMLFQENNLFAHLTVEQNVGL-G 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 585 KIKGIPPKEVEQE-VKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE- 662
Cdd:cd03298 95 LSPGLKLTAEDRQaIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLVLDl 174
|
170 180 190
....*....|....*....|....*....|....*..
gi 1387227070 663 -RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAG 698
Cdd:cd03298 175 hAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
1305-1525 |
1.25e-23 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 102.53 E-value: 1.25e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD-SGTPPTRQAGGGFRH-LGYCPQ--EDVLWP 1380
Cdd:TIGR04521 18 KKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGrDITAKKKKKLKDLRKkVGLVFQfpEHQLFE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 DlTVREhlDLYSAVK--GLTKEEAAlsvSRLADALKLqdqMALPAK-------ALPEGAKRKLSFAlSVLGS-PALLLLD 1450
Cdd:TIGR04521 98 E-TVYK--DIAFGPKnlGLSEEEAE---ERVKEALEL---VGLDEEylerspfELSGGQMRRVAIA-GVLAMePEVLILD 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 1451 EPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHL--KSKFGKDYLLEV 1525
Cdd:TIGR04521 168 EPTAGLDPKGRKEILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVfsDVDELEKIGLDV 244
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
1306-1504 |
1.64e-23 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 100.56 E-value: 1.64e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1306 TAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVV--------FRDSGTPPTRqagggfRHLGYCPQEDV 1377
Cdd:cd03292 15 AALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRvngqdvsdLRGRAIPYLR------RKIGVVFQDFR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1378 LWPDLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQM-ALPAKaLPEGAKRKLSFALSVLGSPALLLLDEPTTGM 1456
Cdd:cd03292 89 LLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHrALPAE-LSGGEQQRVAIARAIVNSPTILIADEPTGNL 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1457 DPEgqlQMWQAIQAIVKSSARGA--LLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:cd03292 168 DPD---TTWEIMNLLKKINKAGTtvVVATHAKELVDTTRHRVIALERGKL 214
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
1308-1522 |
2.44e-23 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 100.49 E-value: 2.44e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1308 VRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPTRqagggfRHLGYCPQEDVLWPDLTV 1384
Cdd:cd03299 15 LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGkdiTNLPPEK------RDISYVPQNYALFPHMTV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1385 REHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQM 1464
Cdd:cd03299 89 YKNIAYGLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKEKL 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 1465 WQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQ----HLKSKFGKDYL 1522
Cdd:cd03299 169 REELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEevfkKPKNEFVAEFL 230
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
1302-1503 |
2.52e-23 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 100.93 E-value: 2.52e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1302 RKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAG--VVVFrdsGtpptRQAGGG--F---RHLGYCPQ 1374
Cdd:COG1119 13 RGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGndVRLF---G----ERRGGEdvWelrKRIGLVSP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1375 EDVLW--PDLTVRE--------HLDLYSAVkglTKEEAALsVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSP 1444
Cdd:COG1119 86 ALQLRfpRDETVLDvvlsgffdSIGLYREP---TDEQRER-ARELLELLGLAHLADRPFGTLSQGEQRRVLIARALVKDP 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 1445 ALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGR 1503
Cdd:COG1119 162 ELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGR 220
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
467-693 |
2.71e-23 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 106.67 E-value: 2.71e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 467 SFEPVSPEFH---RKEAIRIRNLRKEYKGKPEKvEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSAC-TEGSAT 542
Cdd:TIGR00955 6 RNSDVFGRVAqdgSWKQLVSRLRGCFCRERPRK-HLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKgVKGSGS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 543 IynTQLSEIINMEEIRNYTGFCPQFNIYFDFLTVRENLRLFAKIK---GIPPKEVEQEVKSIMMELDMHNIQDVI----- 614
Cdd:TIGR00955 85 V--LLNGMPIDAKEMRAISAYVQQDDLFIPTLTVREHLMFQAHLRmprRVTKKEKRERVDEVLQALGLRKCANTRigvpg 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 615 -AKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTQFMDEADI--LADRKVFLSN 691
Cdd:TIGR00955 163 rVKGLSGGERKRLAFASELLTDPPLLFCDEPTSGLDSFMAYSVVQVLKGLAQKGKTIICTIHQPSSELfeLFDKIILMAE 242
|
..
gi 1387227070 692 GK 693
Cdd:TIGR00955 243 GR 244
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
479-698 |
2.99e-23 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 100.54 E-value: 2.99e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 479 EAIRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEG-SATIYNTQLSEIiNMEEI 557
Cdd:COG1119 2 PLLELRNVTVRRGGKT----ILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGnDVRLFGERRGGE-DVWEL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 558 RNYTGFC-PQFNIYFD-FLTVRENLR--LFAKIkGIPPK---EVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGI 630
Cdd:COG1119 77 RKRIGLVsPALQLRFPrDETVLDVVLsgFFDSI-GLYREptdEQRERARELLELLGLAHLADRPFGTLSQGEQRRVLIAR 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 631 AILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEadILA--DRKVFLSNGKLRCAG 698
Cdd:COG1119 156 ALVKDPELLILDEPTAGLDLGARELLLALLDKlaAEGAPTLVLVTHHVEE--IPPgiTHVLLLKDGRVVAAG 225
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
1305-1504 |
3.07e-23 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 99.74 E-value: 3.07e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAG-VVVF-------RDSGTPPTRqagggfRHLGYCPQED 1376
Cdd:COG2884 15 REALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGqVLVNgqdlsrlKRREIPYLR------RRIGVVFQDF 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1377 VLWPDLTVREHLDLYSAVKGLTKEEAAlsvSRLADALK---LQDQmalpAKALPE----GAKRKLSFALSVLGSPALLLL 1449
Cdd:COG2884 89 RLLPDRTVYENVALPLRVTGKSRKEIR---RRVREVLDlvgLSDK----AKALPHelsgGEQQRVAIARALVNRPELLLA 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 1450 DEPTTGMDPEGQLQMWQAIQAIvksSARGA--LLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:COG2884 162 DEPTGNLDPETSWEIMELLEEI---NRRGTtvLIATHDLELVDRMPKRVLELEDGRL 215
|
|
| galliderm_ABC |
TIGR03740 |
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ... |
481-695 |
3.73e-23 |
|
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.
Pssm-ID: 163452 [Multi-domain] Cd Length: 223 Bit Score: 99.78 E-value: 3.73e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKpekvEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiinmEEIRNY 560
Cdd:TIGR03740 1 LETKNLSKRFGKQ----TAVNNISLTVPKNSVYGLLGPNGAGKSTLLKMITGILRPTSGEIIFDGHPWTR----KDLHKI 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYfDFLTVRENLRLFAKIKGIPpkevEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLL 640
Cdd:TIGR03740 73 GSLIESPPLY-ENLTARENLKVHTTLLGLP----DSRIDEVLNIVDLTNTGKKKAKQFSLGMKQRLGIAIALLNHPKLLI 147
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 641 LDEPTAGLDPFS----RHLVWNFLKErktNHTILFSTQFMDEADILADRKVFLSNGKLR 695
Cdd:TIGR03740 148 LDEPTNGLDPIGiqelRELIRSFPEQ---GITVILSSHILSEVQQLADHIGIISEGVLG 203
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
491-715 |
6.82e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 100.62 E-value: 6.82e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 491 KGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATI------YNTQLSEIinmEEIRNYTGFC 564
Cdd:PRK13646 14 KGTPYEHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVddititHKTKDKYI---RPVRKRIGMV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 565 PQF---NIYFDflTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDM-HNIQDVIAKELSGGQKRKLTFgIAILG-DPQVL 639
Cdd:PRK13646 91 FQFpesQLFED--TVEREIIFGPKNFKMNLDEVKNYAHRLLMDLGFsRDVMSQSPFQMSGGQMRKIAI-VSILAmNPDII 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 640 LLDEPTAGLDPFSRHLVWNFLKERKT--NHTILFSTQFMDEADILADRKVFLSNGKL--RCAGSSLFLKRKWGIGYHLSL 715
Cdd:PRK13646 168 VLDEPTAGLDPQSKRQVMRLLKSLQTdeNKTIILVSHDMNEVARYADEVIVMKEGSIvsQTSPKELFKDKKKLADWHIGL 247
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
481-694 |
8.51e-23 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 100.15 E-value: 8.51e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYkgkPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLS-EIINMEEIRN 559
Cdd:PRK13639 2 LETRDLKYSY---PDGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKyDKKSLLEVRK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YTG----------FCPqfniyfdflTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKltfg 629
Cdd:PRK13639 79 TVGivfqnpddqlFAP---------TVEEDVAFGPLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKR---- 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 630 IAILG----DPQVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:PRK13639 146 VAIAGilamKPEIIVLDEPTSGLDPMGASQIMKLLYDlNKEGITIIISTHDVDLVPVYADKVYVMSDGKI 215
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
1301-1485 |
9.65e-23 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 98.02 E-value: 9.65e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1301 ARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPPTRqAGGGFRHLGYcpqEDVLWP 1380
Cdd:PRK13539 11 VRGGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPD-VAEACHYLGH---RNAMKP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 DLTVREHLDLYSAVKGltkeEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFA-LSVLGSPaLLLLDEPTTGMDPE 1459
Cdd:PRK13539 87 ALTVAENLEFWAAFLG----GEELDIAAALEAVGLAPLAHLPFGYLSAGQKRRVALArLLVSNRP-IWILDEPTAALDAA 161
|
170 180
....*....|....*....|....*...
gi 1387227070 1460 GQLQMWQAIQAivkSSARG--ALLTTHS 1485
Cdd:PRK13539 162 AVALFAELIRA---HLAQGgiVIAATHI 186
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
481-694 |
9.94e-23 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 98.95 E-value: 9.94e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKpekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWsaCTEGSATIYnTQLSEIINMEEIRNY 560
Cdd:cd03299 1 LKVENLSKDWKEF-----KLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGF--IKPDSGKIL-LNGKDITNLPPEKRD 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLL 640
Cdd:cd03299 73 ISYVPQNYALFPHMTVYKNIAYGLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILL 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 641 LDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:cd03299 153 LDEPFSALDVRTKEKLREELKKirKEFGVTVLHVTHDFEEAWALADKVAIMLNGKL 208
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
481-698 |
1.05e-22 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 97.00 E-value: 1.05e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEKVeaLQGICLDVYEGQLTAILGHSGAGKSSLLS-ILGGWSAcTEGSATIYNTQLSEIinMEEIRN 559
Cdd:cd03247 1 LSINNVSFSYPEQEQQV--LKNLSLELKQGEKIALLGRSGSGKSTLLQlLTGDLKP-QQGEITLDGVPVSDL--EKALSS 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YTGFCPQFNIYFDfLTVRENLrlfakikgippkeveqevksimmeldmhniqdviAKELSGGQKRKLTFGIAILGDPQVL 639
Cdd:cd03247 76 LISVLNQRPYLFD-TTLRNNL----------------------------------GRRFSGGERQRLALARILLQDAPIV 120
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 640 LLDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTQFMDEADiLADRKVFLSNGKLRCAG 698
Cdd:cd03247 121 LLDEPTVGLDPITERQLLSLIFEVLKDKTLIWITHHLTGIE-HMDKILFLENGKIIMQG 178
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
481-715 |
1.06e-22 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 100.09 E-value: 1.06e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGK-PEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLS---EIINMEE 556
Cdd:PRK13634 3 ITFQKVEHRYQYKtPFERRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITagkKNKKLKP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 557 IRNYTGFCPQF--NIYFDfLTVRENLRLFAKIKGIPPKEVEQEVKSI--MMELDmhniQDVIAK---ELSGGQKRKltfg 629
Cdd:PRK13634 83 LRKKVGIVFQFpeHQLFE-ETVEKDICFGPMNFGVSEEDAKQKAREMieLVGLP----EELLARspfELSGGQMRR---- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 630 IAILG----DPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGS--SL 701
Cdd:PRK13634 154 VAIAGvlamEPEVLVLDEPTAGLDPKGRKEMMEMFYKlhKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTprEI 233
|
250
....*....|....
gi 1387227070 702 FLKRKWGIGYHLSL 715
Cdd:PRK13634 234 FADPDELEAIGLDL 247
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
481-650 |
1.67e-22 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 98.14 E-value: 1.67e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGkpekVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSE-IINMEEIRN 559
Cdd:COG1126 2 IEIENLHKSFGD----LEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTDsKKDINKLRR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YTGFCPQ-FNIyFDFLTVRENLRLfA--KIKGIPPKEVEQEVksiMMELDMHNIQDVIAK---ELSGGQK-RkltfgIAI 632
Cdd:COG1126 78 KVGMVFQqFNL-FPHLTVLENVTL-ApiKVKKMSKAEAEERA---MELLERVGLADKADAypaQLSGGQQqR-----VAI 147
|
170 180
....*....|....*....|..
gi 1387227070 633 ---LG-DPQVLLLDEPTAGLDP 650
Cdd:COG1126 148 araLAmEPKVMLFDEPTSALDP 169
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
484-661 |
2.03e-22 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 96.54 E-value: 2.03e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 484 RNLRKEYKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGW--SACTEGSATIyNTQLseiiNMEEIRNYT 561
Cdd:cd03232 7 KNLNYTVPVKGGKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGRktAGVITGEILI-NGRP----LDKNFQRST 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 562 GFCPQFNIYFDFLTVRENLRLFAKIKGippkeveqevksimmeldmhniqdviakeLSGGQKRKLTFGIAILGDPQVLLL 641
Cdd:cd03232 82 GYVEQQDVHSPNLTVREALRFSALLRG-----------------------------LSVEQRKRLTIGVELAAKPSILFL 132
|
170 180
....*....|....*....|
gi 1387227070 642 DEPTAGLDPFSRHLVWNFLK 661
Cdd:cd03232 133 DEPTSGLDSQAAYNIVRFLK 152
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
481-663 |
2.17e-22 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 97.79 E-value: 2.17e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSatIYntqlseiINMEEIRNY 560
Cdd:COG1137 4 LEAENLVKSYGKRT----VVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGR--IF-------LDGEDITHL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 T---------GFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIA 631
Cdd:COG1137 71 PmhkrarlgiGYLPQEASIFRKLTVEDNILAVLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARA 150
|
170 180 190
....*....|....*....|....*....|....*.
gi 1387227070 632 ILGDPQVLLLDEPTAGLDPFS----RHLVwNFLKER 663
Cdd:COG1137 151 LATNPKFILLDEPFAGVDPIAvadiQKII-RHLKER 185
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
481-694 |
2.64e-22 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 100.26 E-value: 2.64e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINME--EIR 558
Cdd:PRK11153 2 IELKNISKVFPQGGRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKElrKAR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 559 NYTGFCPQfniYFDFL---TVRENLRLFAKIKGIPPKEVEQEVKSImmeLDMHNIQD---VIAKELSGGQKRKLtfGIA- 631
Cdd:PRK11153 82 RQIGMIFQ---HFNLLssrTVFDNVALPLELAGTPKAEIKARVTEL---LELVGLSDkadRYPAQLSGGQKQRV--AIAr 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 632 -ILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:PRK11153 154 aLASNPKVLLCDEATSALDPATTRSILELLKDinRELGLTIVLITHEMDVVKRICDRVAVIDAGRL 219
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
482-694 |
3.02e-22 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 97.80 E-value: 3.02e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 482 RIRNLRKEYKGkpekVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLS-----EIINMee 556
Cdd:COG0411 6 EVRGLTKRFGG----LVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITglpphRIARL-- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 557 irnytG----FcpQFNIYFDFLTVRENLRL----------FAKIKGIPP-----KEVEQEVKSIMMELDMHNIQDVIAKE 617
Cdd:COG0411 80 -----GiartF--QNPRLFPELTVLENVLVaaharlgrglLAALLRLPRarreeREARERAEELLERVGLADRADEPAGN 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 618 LSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILfstqfMDEADI-----LADRKVFLS 690
Cdd:COG0411 153 LSYGQQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRlrDERGITIL-----LIEHDMdlvmgLADRIVVLD 227
|
....
gi 1387227070 691 NGKL 694
Cdd:COG0411 228 FGRV 231
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
480-694 |
4.35e-22 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 97.41 E-value: 4.35e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGKpekvEALQGICLDVYEGQLTAILGHSGAGKSSLLSIL-------GGwsACTEGSAT-----IYNTQ 547
Cdd:COG1117 11 KIEVRNLNVYYGDK----QALKDINLDIPENKVTALIGPSGCGKSTLLRCLnrmndliPG--ARVEGEILldgedIYDPD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 548 lseiINMEEIRNYTGFCPQ------FNIYfdfltvrENLRLFAKIKGIPPKE-----VEQ---------EVKSimmELDM 607
Cdd:COG1117 85 ----VDVVELRRRVGMVFQkpnpfpKSIY-------DNVAYGLRLHGIKSKSeldeiVEEslrkaalwdEVKD---RLKK 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 608 HniqdviAKELSGGQKRKLTfgIA--ILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTQFMDEADILADR 685
Cdd:COG1117 151 S------ALGLSGGQQQRLC--IAraLAVEPEVLLMDEPTSALDPISTAKIEELILELKKDYTIVIVTHNMQQAARVSDY 222
|
....*....
gi 1387227070 686 KVFLSNGKL 694
Cdd:COG1117 223 TAFFYLGEL 231
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
481-713 |
4.38e-22 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 96.84 E-value: 4.38e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEkVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRNY 560
Cdd:cd03249 1 IEFKNVSFRYPSRPD-VPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDL-NLRWLRSQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDfLTVRENLRLfakikGIPPKEVEQEVKSIMMEldmhNIQDVIAK--------------ELSGGQKRKL 626
Cdd:cd03249 79 IGLVSQEPVLFD-GTIAENIRY-----GKPDATDEEVEEAAKKA----NIHDFIMSlpdgydtlvgergsQLSGGQKQRI 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 627 TFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTIL-----FSTqfmdeadIL-ADRKVFLSNGKLRCAGSS 700
Cdd:cd03249 149 AIARALLRNPKILLLDEATSALDAESEKLVQEALDRAMKGRTTIviahrLST-------IRnADLIAVLQNGQVVEQGTH 221
|
250
....*....|...
gi 1387227070 701 LFLKRKWGIGYHL 713
Cdd:cd03249 222 DELMAQKGVYAKL 234
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
1306-1504 |
4.79e-22 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 94.42 E-value: 4.79e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1306 TAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPPT-----RQAGGGFRHlgycpQedvlwp 1380
Cdd:cd03216 14 KALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFAsprdaRRAGIAMVY-----Q------ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 dltvrehldlysavkgltkeeaaLSVSrladalklQDQMALPAKALPEGAKrklsfalsvlgspaLLLLDEPTTGMDPEG 1460
Cdd:cd03216 83 -----------------------LSVG--------ERQMVEIARALARNAR--------------LLILDEPTAALTPAE 117
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1387227070 1461 QLQMWQAIQAIvKSSARGALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:cd03216 118 VERLFKVIRRL-RAQGVAVIFISHRLDEVFEIADRVTVLRDGRV 160
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
480-706 |
5.13e-22 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 97.88 E-value: 5.13e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKgkpEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRN 559
Cdd:PRK13647 4 IIEVEDLHFRYK---DGTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAE-NEKWVRS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YTGFC---PQFNIYFDflTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKltfgIAILG-- 634
Cdd:PRK13647 80 KVGLVfqdPDDQVFSS--TVWDDVAFGPVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKR----VAIAGvl 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 635 --DPQVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGSSLFLKRK 706
Cdd:PRK13647 154 amDPDVIVLDEPMAYLDPRGQETLMEILDRlHNQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKSLLTDE 228
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
1303-1503 |
8.37e-22 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 93.99 E-value: 8.37e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1303 KTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTpPTRQAGGG--FRHLGYCPQEDVLWP 1380
Cdd:cd03228 13 RPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILI--DGV-DLRDLDLEslRKNIAYVPQDPFLFS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 DlTVREHLdlysavkgltkeeaaLSVsrladalklqdqmalpakalpeGAKRKLSFALSVLGSPALLLLDEPTTGMDPEG 1460
Cdd:cd03228 90 G-TIRENI---------------LSG----------------------GQRQRIAIARALLRDPPILILDEATSALDPET 131
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1387227070 1461 QLQMWQAIQAIvkSSARGALLTTHSMAEAEAvCDRVAIMVSGR 1503
Cdd:cd03228 132 EALILEALRAL--AKGKTVIVIAHRLSTIRD-ADRIIVLDDGR 171
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
1299-1513 |
8.45e-22 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 96.22 E-value: 8.45e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1299 FSARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPTRQAgggfRHLGYCPQE 1375
Cdd:cd03295 8 KRYGGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGediREQDPVELR----RKIGYVIQQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1376 DVLWPDLTVREHLDLYSAVKGLTKEEAAlsvSRLADALKLqdqMALPAKALPE--------GAKRKLSFALSVLGSPALL 1447
Cdd:cd03295 84 IGLFPHMTVEENIALVPKLLKWPKEKIR---ERADELLAL---VGLDPAEFADryphelsgGQQQRVGVARALAADPPLL 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 1448 LLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHL 1513
Cdd:cd03295 158 LMDEPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEI 223
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
1307-1534 |
1.13e-21 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 99.14 E-value: 1.13e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPTRqagggfRHLGYCPQEDVLWPDLT 1383
Cdd:PRK11607 34 AVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGvdlSHVPPYQ------RPINMMFQSYALFPHMT 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1384 VREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQ 1463
Cdd:PRK11607 108 VEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALDKKLRDR 187
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 1464 MWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGS----VQHLKSKFGKDYLLEVKVKALTLVE 1534
Cdd:PRK11607 188 MQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEpeeiYEHPTTRYSAEFIGSVNVFEGVLKE 262
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
1304-1513 |
1.24e-21 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 101.38 E-value: 1.24e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1304 TKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTRQAGGGFR-HLGYCPQEDVLWPDl 1382
Cdd:COG4987 347 GRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITL--GGVDLRDLDEDDLRrRIAVVPQRPHLFDT- 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1383 TVREHLDLysAVKGLTKEE--AALSVSRLADALKlqdqmalpakALPE---------------GAKRKLSFALSVLGSPA 1445
Cdd:COG4987 424 TLRENLRL--ARPDATDEElwAALERVGLGDWLA----------ALPDgldtwlgeggrrlsgGERRRLALARALLRDAP 491
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 1446 LLLLDEPTTGMDPEGQLQMWQAIQAIVKSsaRGALLTTHSMAEAEAVcDRVAIMVSGRLRCIGSVQHL 1513
Cdd:COG4987 492 ILLLDEPTEGLDAATEQALLADLLEALAG--RTVLLITHRLAGLERM-DRILVLEDGRIVEQGTHEEL 556
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
1295-1502 |
1.40e-21 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 94.63 E-value: 1.40e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1295 KKRCFSARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPPTRQagggFRHLGYCPQ 1374
Cdd:cd03226 3 ENISFSYKKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKAKER----RKSIGYVMQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1375 E--DVLWPDlTVREHLDlysavkgLTKEEAALSVSRLADALKLQDQMALPAK---ALPEGAKRKLSFALSVLGSPALLLL 1449
Cdd:cd03226 79 DvdYQLFTD-SVREELL-------LGLKELDAGNEQAETVLKDLDLYALKERhplSLSGGQKQRLAIAAALLSGKDLLIF 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 1450 DEPTTGMDPEGqlqMWQAIQAIVKSSARGA--LLTTHSMAEAEAVCDRVAIMVSG 1502
Cdd:cd03226 151 DEPTSGLDYKN---MERVGELIRELAAQGKavIVITHDYEFLAKVCDRVLLLANG 202
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
1307-1504 |
1.46e-21 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 94.96 E-value: 1.46e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPT--RqagggfRHLGYCPQEDVLWPD 1381
Cdd:cd03245 19 ALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGtdiRQLDPAdlR------RNIGYVPQDVTLFYG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 lTVREHLDLYsavKGLTKEEAALSVSRLADALKLQDQ----MALP----AKALPEGAKRKLSFALSVLGSPALLLLDEPT 1453
Cdd:cd03245 93 -TLRDNITLG---APLADDERILRAAELAGVTDFVNKhpngLDLQigerGRGLSGGQRQAVALARALLNDPPILLLDEPT 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 1454 TGMDPEGQLQMWQAIQAIVKSsaRGALLTTHSMAeAEAVCDRVAIMVSGRL 1504
Cdd:cd03245 169 SAMDMNSEERLKERLRQLLGD--KTLIIITHRPS-LLDLVDRIIVMDSGRI 216
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
480-694 |
1.58e-21 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 94.96 E-value: 1.58e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKgkPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiINMEEIRN 559
Cdd:cd03245 2 RIEFRNVSFSYP--NQEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQ-LDPADLRR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YTGFCPQfNIYFDFLTVRENLRLFAkikgipPKEVEQEvksIMMELDMHNIQDVIAK--------------ELSGGQKRK 625
Cdd:cd03245 79 NIGYVPQ-DVTLFYGTLRDNITLGA------PLADDER---ILRAAELAGVTDFVNKhpngldlqigergrGLSGGQRQA 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 626 LTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTQFMDEADiLADRKVFLSNGKL 694
Cdd:cd03245 149 VALARALLNDPPILLLDEPTSAMDMNSEERLKERLRQLLGDKTLIIITHRPSLLD-LVDRIIVMDSGRI 216
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
500-692 |
2.04e-21 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 94.84 E-value: 2.04e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 500 LQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSE--IINMEEIRNYTgfcpqfniYFDFLTVR 577
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEpgPDRMVVFQNYS--------LLPWLTVR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 578 ENLRLfaKIKGIPPKEVEQEVKSIMME-LDMHNIQDVIAK---ELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSR 653
Cdd:TIGR01184 73 ENIAL--AVDRVLPDLSKSERRAIVEEhIALVGLTEAADKrpgQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTR 150
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1387227070 654 HLVWNFLKERKTNH--TILFSTQFMDEADILADRKVFLSNG 692
Cdd:TIGR01184 151 GNLQEELMQIWEEHrvTVLMVTHDVDEALLLSDRVVMLTNG 191
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
1304-1514 |
2.50e-21 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 94.88 E-value: 2.50e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1304 TKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTRQAGGGFRHL----GYCPQEDVLW 1379
Cdd:cd03261 12 GRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLI--DGEDISGLSEAELYRLrrrmGMLFQSGALF 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1380 PDLTV--------REHLDlysavkgLTKEEaalsVSRLAdALKLQ--------DQMalPAKaLPEGAKRKLSFALSVLGS 1443
Cdd:cd03261 90 DSLTVfenvafplREHTR-------LSEEE----IREIV-LEKLEavglrgaeDLY--PAE-LSGGMKKRVALARALALD 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 1444 PALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLK 1514
Cdd:cd03261 155 PELLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELR 225
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
480-714 |
2.67e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 96.05 E-value: 2.67e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYK-GKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEII---NME 555
Cdd:PRK13641 2 SIKFENVDYIYSpGTPMEKKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPETgnkNLK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 556 EIRNYTGFCPQF--NIYFDFlTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHniQDVIAK---ELSGGQKRKLTFGI 630
Cdd:PRK13641 82 KLRKKVSLVFQFpeAQLFEN-TVLKDVEFGPKNFGFSEDEAKEKALKWLKKVGLS--EDLISKspfELSGGQMRRVAIAG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 631 AILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKL--RCAGSSLFLKRKW 707
Cdd:PRK13641 159 VMAYEPEILCLDEPAAGLDPEGRKEMMQLFKDyQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLikHASPKEIFSDKEW 238
|
....*..
gi 1387227070 708 GIGYHLS 714
Cdd:PRK13641 239 LKKHYLD 245
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
1305-1514 |
3.29e-21 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 94.66 E-value: 3.29e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF--RDSGTPPTRQAGGGFRHLGYCPQEDVLWPDL 1382
Cdd:COG1127 18 RVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVdgQDITGLSEKELYELRRRIGMLFQGGALFDSL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1383 TV--------REHLDLysavkglTKEEA------ALSVSRLADALKLqdqmaLPAkalpE---GAKRKLSFALSVLGSPA 1445
Cdd:COG1127 98 TVfenvafplREHTDL-------SEAEIrelvleKLELVGLPGAADK-----MPS----ElsgGMRKRVALARALALDPE 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1387227070 1446 LLLLDEPTTGMDPEG-----QLqmwqaIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLK 1514
Cdd:COG1127 162 ILLYDEPTAGLDPITsavidEL-----IRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEELL 230
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
1305-1509 |
4.23e-21 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 93.84 E-value: 4.23e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPTRqagggfRHLGYCPQEDVLWPD 1381
Cdd:cd03300 13 FVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGkdiTNLPPHK------RPVNTVFQNYALFPH 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 LTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQ 1461
Cdd:cd03300 87 LTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGALDLKLR 166
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1387227070 1462 LQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGS 1509
Cdd:cd03300 167 KDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGT 214
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
478-694 |
4.26e-21 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 99.47 E-value: 4.26e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 478 KEAIRIRNLRKEYkgkPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiINMEEI 557
Cdd:COG1132 337 RGEIEFENVSFSY---PGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRD-LTLESL 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 558 RNYTGFCPQFNIYFDfLTVRENLRLFAkiKGIPPKEVEQEVKsimmeldMHNIQDVIAK--------------ELSGGQK 623
Cdd:COG1132 413 RRQIGVVPQDTFLFS-GTIRENIRYGR--PDATDEEVEEAAK-------AAQAHEFIEAlpdgydtvvgergvNLSGGQR 482
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 624 RKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTIL-----FSTqfmdeadIL-ADRKVFLSNGKL 694
Cdd:COG1132 483 QRIAIARALLKDPPILILDEATSALDTETEALIQEALERLMKGRTTIviahrLST-------IRnADRILVLDDGRI 552
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
1301-1504 |
4.39e-21 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 93.87 E-value: 4.39e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1301 ARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITG---DTKPTAGVVVFRdsGTPPTRQAgggFR-HLGYCPQED 1376
Cdd:cd03234 16 WNKYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGrveGGGTTSGQILFN--GQPRKPDQ---FQkCVAYVRQDD 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1377 VLWPDLTVREHLdLYSAV---------KGLTKEEAALSVSRLADALKLQDQMalpaKALPEGAKRKLSFALSVLGSPALL 1447
Cdd:cd03234 91 ILLPGLTVRETL-TYTAIlrlprkssdAIRKKRVEDVLLRDLALTRIGGNLV----KGISGGERRRVSIAVQLLWDPKVL 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 1448 LLDEPTTGMDPEGQLQMWQAIQAIVKSSaRGALLTTHS-MAEAEAVCDRVAIMVSGRL 1504
Cdd:cd03234 166 ILDEPTSGLDSFTALNLVSTLSQLARRN-RIVILTIHQpRSDLFRLFDRILLLSSGEI 222
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
480-699 |
4.51e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 95.20 E-value: 4.51e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYK-GKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQL---SEIINME 555
Cdd:PRK13649 2 GINLQNVSYTYQaGTPFEGRALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLItstSKNKDIK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 556 EIRNYTGFCPQF--NIYFDfLTVRENLRLFAKIKGIPPKEVEQEVKSimmELDMHNI-QDVIAK---ELSGGQKRKltfg 629
Cdd:PRK13649 82 QIRKKVGLVFQFpeSQLFE-ETVLKDVAFGPQNFGVSQEEAEALARE---KLALVGIsESLFEKnpfELSGGQMRR---- 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 630 IAILG----DPQVLLLDEPTAGLDPFSR-HLVWNFLKERKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:PRK13649 154 VAIAGilamEPKILVLDEPTAGLDPKGRkELMTLFKKLHQSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGK 228
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
480-694 |
5.52e-21 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 94.05 E-value: 5.52e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGKpekvEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINM----- 554
Cdd:PRK11264 3 AIEVKNLVKKFHGQ----TVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDITIDTARSLsqqkg 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 555 --EEIRNYTGFCPQ-FNIyFDFLTVRENLRLFAKI-KGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGI 630
Cdd:PRK11264 79 liRQLRQHVGFVFQnFNL-FPHRTVLENIIEGPVIvKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIAR 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 631 AILGDPQVLLLDEPTAGLDPfsrHLVWNFLKERKT----NHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:PRK11264 158 ALAMRPEVILFDEPTSALDP---ELVGEVLNTIRQlaqeKRTMVIVTHEMSFARDVADRAIFMDQGRI 222
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
479-699 |
6.65e-21 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 93.61 E-value: 6.65e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 479 EAIRIRNLRKEY------------------KGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGS 540
Cdd:COG1134 3 SMIEVENVSKSYrlyhepsrslkelllrrrRTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 541 ATIyNTQLSEIINMEeirnyTGFCPQfniyfdfLTVRENLRLFAKIKGIPPKEVEQEVKSImmeLDMHNIQDVI---AKE 617
Cdd:COG1134 83 VEV-NGRVSALLELG-----AGFHPE-------LTGRENIYLNGRLLGLSRKEIDEKFDEI---VEFAELGDFIdqpVKT 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 618 LSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNH-TILFSTQFMDEADILADRKVFLSNGKLRC 696
Cdd:COG1134 147 YSSGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLARIRELRESGrTVIFVSHSMGAVRRLCDRAIWLEKGRLVM 226
|
...
gi 1387227070 697 AGS 699
Cdd:COG1134 227 DGD 229
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
480-680 |
6.77e-21 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 99.81 E-value: 6.77e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKgkpeKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTqlseiiNMEEIRN 559
Cdd:NF033858 1 VARLEGVSHRYG----KTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGG------DMADARH 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YTGFCPQF---------NIYFDfLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGI 630
Cdd:NF033858 71 RRAVCPRIaympqglgkNLYPT-LSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCC 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 631 AILGDPQVLLLDEPTAGLDPFSRHLVWNF---LKERKTNHTILFSTQFMDEAD 680
Cdd:NF033858 150 ALIHDPDLLILDEPTTGVDPLSRRQFWELidrIRAERPGMSVLVATAYMEEAE 202
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
1298-1516 |
7.33e-21 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 98.68 E-value: 7.33e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1298 CFSARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTRQAGGGFR-HLGYCPQED 1376
Cdd:COG4988 343 SFSYPGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILI--NGVDLSDLDPASWRrQIAWVPQNP 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1377 VLWPDlTVREHLDLYSAvkGLTKEE--AALSVSRLADALK-LQDQMALP----AKALPEGAKRKLSFALSVLGSPALLLL 1449
Cdd:COG4988 421 YLFAG-TIRENLRLGRP--DASDEEleAALEAAGLDEFVAaLPDGLDTPlgegGRGLSGGQAQRLALARALLRDAPLLLL 497
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 1450 DEPTTGMDPEGQLQMWQAIQAIVKSsaRGALLTTHSMAEAEAvCDRVAIMVSGRLRCIGSVQHLKSK 1516
Cdd:COG4988 498 DEPTAHLDAETEAEILQALRRLAKG--RTVILITHRLALLAQ-ADRILVLDDGRIVEQGTHEELLAK 561
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
1306-1504 |
8.14e-21 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 98.17 E-value: 8.14e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1306 TAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRdsGTP----PTRQAgggfRHLG----YcpQEDV 1377
Cdd:COG1129 18 KALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLD--GEPvrfrSPRDA----QAAGiaiiH--QELN 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1378 LWPDLTVRE--HLDLYSAVKGL-----TKEEAA---------LSVSRLADALKL-QDQMALPAKALPEGAKrklsfalsv 1440
Cdd:COG1129 90 LVPNLSVAEniFLGREPRRGGLidwraMRRRARellarlgldIDPDTPVGDLSVaQQQLVEIARALSRDAR--------- 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1387227070 1441 lgspaLLLLDEPTTGMDPEGQLQMWQAIQAIvKSSARGALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:COG1129 161 -----VLILDEPTASLTEREVERLFRIIRRL-KAQGVAIIYISHRLDEVFEIADRVTVLRDGRL 218
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
477-699 |
8.23e-21 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 96.55 E-value: 8.23e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 477 RKEAIRIRNLRKEYKGKpekvEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSAtiyntqlseIINMEE 556
Cdd:PRK09452 11 LSPLVELRGISKSFDGK----EVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRI---------MLDGQD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 557 IrnyTGFCPQ-------FNIY--FDFLTVRENLRLFAKIKGIPPKEVEQEVKSI--MMELDmhNIQDVIAKELSGGQKRK 625
Cdd:PRK09452 78 I---THVPAEnrhvntvFQSYalFPHMTVFENVAFGLRMQKTPAAEITPRVMEAlrMVQLE--EFAQRKPHQLSGGQQQR 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 626 LTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLK--ERKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:PRK09452 153 VAIARAVVNKPKVLLLDESLSALDYKLRKQMQNELKalQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGT 228
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
1306-1513 |
8.96e-21 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 95.91 E-value: 8.96e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1306 TAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF--RD-SGTPPTRqagggfRHLGYCPQEDVLWPDL 1382
Cdd:COG3839 17 EALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIggRDvTDLPPKD------RNIAMVFQSYALYPHM 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1383 TVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSfalsvLG-----SPALLLLDEPTTGMD 1457
Cdd:COG3839 91 TVYENIAFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVA-----LGralvrEPKVFLLDEPLSNLD 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 1458 PEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHL 1513
Cdd:COG3839 166 AKLRVEMRAEIKRLHRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTPEEL 221
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
481-694 |
9.11e-21 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 90.95 E-value: 9.11e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGkpekVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGsaTIYntqlseiINMEEIRny 560
Cdd:cd03216 1 LELRGITKRFGG----VKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSG--EIL-------VDGKEVS-- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 tgfcpqfniyfdFLTVRENLRLfakikGIPPkeVEQevksimmeldmhniqdviakeLSGGQKRKLTFGIAILGDPQVLL 640
Cdd:cd03216 66 ------------FASPRDARRA-----GIAM--VYQ---------------------LSVGERQMVEIARALARNARLLI 105
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 641 LDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:cd03216 106 LDEPTAALTPAEVERLFKVIRRlRAQGVAVIFISHRLDEVFEIADRVTVLRDGRV 160
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
1305-1511 |
9.44e-21 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 93.68 E-value: 9.44e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF--RD-SGTPPTRQAgggfRHLGYCPQEDVLWPD 1381
Cdd:PRK13548 15 RTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLngRPlADWSPAELA----RRRAVLPQHSSLSFP 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 LTVRE--HLDLYSAVKGLTKEEAAlsvsrLADALKLQDQMALPAKALPE---GAKRKLSFAlSVL-------GSPALLLL 1449
Cdd:PRK13548 91 FTVEEvvAMGRAPHGLSRAEDDAL-----VAAALAQVDLAHLAGRDYPQlsgGEQQRVQLA-RVLaqlwepdGPPRWLLL 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 1450 DEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQ 1511
Cdd:PRK13548 165 DEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLVADGTPA 226
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
1307-1523 |
1.56e-20 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 98.37 E-value: 1.56e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdsgtpptrqagGGF-----------RHLGYCPQE 1375
Cdd:COG2274 490 VLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILI------------DGIdlrqidpaslrRQIGVVLQD 557
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1376 DVLWPDlTVREHLDLysAVKGLTKEEaALSVSRLADAlkLQDQMALP----------AKALPEGAKRKLSFALSVLGSPA 1445
Cdd:COG2274 558 VFLFSG-TIRENITL--GDPDATDEE-IIEAARLAGL--HDFIEALPmgydtvvgegGSNLSGGQRQRLAIARALLRNPR 631
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1446 LLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARgaLLTTH--SMAEAeavCDRVAIMVSGRLRCIGSVQHLKSKFGKDYLL 1523
Cdd:COG2274 632 ILILDEATSALDAETEAIILENLRRLLKGRTV--IIIAHrlSTIRL---ADRIIVLDKGRIVEDGTHEELLARKGLYAEL 706
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
1308-1504 |
1.61e-20 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 90.35 E-value: 1.61e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1308 VRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVvfRDSGTPPTRQAGGGFR-HLGYCPQEDVLWPDlTVRE 1386
Cdd:cd03246 18 LRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRV--RLDGADISQWDPNELGdHVGYLPQDDELFSG-SIAE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1387 HLdlysavkgltkeeaalsvsrladalklqdqmalpakaLPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQ 1466
Cdd:cd03246 95 NI-------------------------------------LSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERALNQ 137
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1387227070 1467 AIQAIvksSARGA--LLTTHSMaEAEAVCDRVAIMVSGRL 1504
Cdd:cd03246 138 AIAAL---KAAGAtrIVIAHRP-ETLASADRILVLEDGRV 173
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
480-695 |
1.67e-20 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 93.18 E-value: 1.67e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGKpekvEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSAC-----TEGSATIYNTQLSEI-IN 553
Cdd:PRK14258 7 AIKVNNLSFYYDTQ----KILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELesevrVEGRVEFFNQNIYERrVN 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 554 MEEIRNYTGFC-PQFNIYFdfLTVRENLRLFAKIKGIPPK-EVEQEVKSIMMELDMHN-IQDVIAK---ELSGGQKRKLT 627
Cdd:PRK14258 83 LNRLRRQVSMVhPKPNLFP--MSVYDNVAYGVKIVGWRPKlEIDDIVESALKDADLWDeIKHKIHKsalDLSGGQQQRLC 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 628 FGIAILGDPQVLLLDEPTAGLDPFS----RHLVWNFlkERKTNHTILFSTQFMDEADILADRKVFLSNGKLR 695
Cdd:PRK14258 161 IARALAVKPKVLLMDEPCFGLDPIAsmkvESLIQSL--RLRSELTMVIVSHNLHQVSRLSDFTAFFKGNENR 230
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
481-699 |
2.59e-20 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 91.91 E-value: 2.59e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEKVeaLQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRNY 560
Cdd:cd03251 1 VEFKNVTFRYPGDGPPV--LRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDY-TLASLRRQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFlTVRENLRlFAKiKGIPPKEVEQEVK-----SIMMELDmHNIQDVIAK---ELSGGQKRKLTFGIAI 632
Cdd:cd03251 78 IGLVSQDVFLFND-TVAENIA-YGR-PGATREEVEEAARaanahEFIMELP-EGYDTVIGErgvKLSGGQRQRIAIARAL 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 633 LGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTIL-----FSTqFMDeadilADRKVFLSNGKLRCAGS 699
Cdd:cd03251 154 LKDPPILILDEATSALDTESERLVQAALERLMKNRTTFviahrLST-IEN-----ADRIVVLEDGKIVERGT 219
|
|
| thiQ |
TIGR01277 |
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ... |
481-694 |
2.85e-20 |
|
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]
Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 91.08 E-value: 2.85e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEKVEalqgicLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNtqlseiinmeeiRNY 560
Cdd:TIGR01277 1 LALDKVRYEYEHLPMEFD------LNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVND------------QSH 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCP---------QFNIYFDFLTVRENLRLfakikGIPP-----KEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKL 626
Cdd:TIGR01277 63 TGLAPyqrpvsmlfQENNLFAHLTVRQNIGL-----GLHPglklnAEQQEKVVDAAQQVGIADYLDRLPEQLSGGQRQRV 137
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 627 TFGIAILGDPQVLLLDEPTAGLDPFSRH----LVWNFLKERKTnhTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:TIGR01277 138 ALARCLVRPNPILLLDEPFSALDPLLREemlaLVKQLCSERQR--TLLMVTHHLSDARAIASQIAVVSQGKI 207
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
478-694 |
3.82e-20 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 91.76 E-value: 3.82e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 478 KEAIRIRNLRKEYKGKpekvEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWS----ACTEGSATIYNTQ--LSEI 551
Cdd:PRK14239 3 EPILQVSDLSVYYNKK----KALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMNdlnpEVTITGSIVYNGHniYSPR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 552 INMEEIRNYTGFCPQFNIYFDFlTVRENLRLFAKIKGIPPKEVEQEV--KSIMMELDMHNIQDVI---AKELSGGQKRKL 626
Cdd:PRK14239 79 TDTVDLRKEIGMVFQQPNPFPM-SIYENVVYGLRLKGIKDKQVLDEAveKSLKGASIWDEVKDRLhdsALGLSGGQQQRV 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 627 TFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:PRK14239 158 CIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDDYTMLLVTRSMQQASRISDRTGFFLDGDL 225
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
478-803 |
5.06e-20 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 93.65 E-value: 5.06e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 478 KEAIRIRNLRKEYKgkpeKVEALQGICLDVYEGQLTAILGHSGAG--KSSLLSILGGWSA----------CTEGSATIYN 545
Cdd:NF000106 11 RNAVEVRGLVKHFG----EVKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*GPDAgrrpwrf*twCANRRALRRT 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 546 TQLSEIINMEEIRNYTGfcpqfniyfdfltvRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRK 625
Cdd:NF000106 87 IG*HRPVR*GRRESFSG--------------RENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 626 LTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKER-KTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGSSLFLK 704
Cdd:NF000106 153 LDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMvRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELK 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 705 RKWGiGYHLSLHRNERCNTERITSLITQHISD--AKLTAENEEKLVyTLPLERTDKFPDLCRDLenssdqGIMSFGVS-- 780
Cdd:NF000106 233 TKVG-GRTLQIRPAHAAELDRMVGAIAQAGLDgiAGATADHEDGVV-NVPIVSDEQLSAVVGML------GERGFTISgh 304
|
330 340
....*....|....*....|....*.
gi 1387227070 781 ---MTTLNEVFLNLKGRSAINGPDPG 803
Cdd:NF000106 305 qhpSAQL*EVFLAITGQKTSEAADGG 330
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
480-694 |
5.76e-20 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 90.84 E-value: 5.76e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKgkpeKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQ--LSEIINMEEI 557
Cdd:COG4161 2 SIQLKNINCFYG----SHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQfdFSQKPSEKAI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 558 R----NYTGFCPQFNIYfDFLTVRENLrLFAKIK--GIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIA 631
Cdd:COG4161 78 RllrqKVGMVFQQYNLW-PHLTVMENL-IEAPCKvlGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARA 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1387227070 632 ILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:COG4161 156 LMMEPQVLLFDEPTAALDPEITAQVVEIIRElSQTGITQVIVTHEVEFARKVASQVVYMEKGRI 219
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
1277-1508 |
6.71e-20 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 95.25 E-value: 6.71e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1277 LDEPVIMASCLHKEYkqekkrCFSARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFR---- 1352
Cdd:TIGR03269 275 VGEPIIKVRNVSKRY------ISVDRGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVRvgde 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1353 --DSGTPPTRQAGGGFRHLGYCPQEDVLWPDLTVREHL---------DLYSAVK--------GLTKEEAALSVSRLADAL 1413
Cdd:TIGR03269 349 wvDMTKPGPDGRGRAKRYIGILHQEYDLYPHRTVLDNLteaiglelpDELARMKavitlkmvGFDEEKAEEILDKYPDEL 428
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1414 KlqdqmalpakalpEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVC 1493
Cdd:TIGR03269 429 S-------------EGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVC 495
|
250
....*....|....*
gi 1387227070 1494 DRVAIMVSGRLRCIG 1508
Cdd:TIGR03269 496 DRAALMRDGKIVKIG 510
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
481-694 |
7.61e-20 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 91.17 E-value: 7.61e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEK--------------------VEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGS 540
Cdd:cd03294 1 IKIKGLYKIFGKNPQKafkllakgkskeeilkktgqTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 541 ATIYNTQLSEIiNMEEIRN----YTGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAK 616
Cdd:cd03294 81 VLIDGQDIAAM-SRKELRElrrkKISMVFQSFALLPHRTVLENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 617 ELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWN-FLK-ERKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:cd03294 160 ELSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIRREMQDeLLRlQAELQKTIVFITHDLDEALRLGDRIAIMKDGRL 239
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
1309-1484 |
7.98e-20 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 89.48 E-value: 7.98e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1309 RNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSgtpPTRQAGGGFRHlgycpqeDVLW--------P 1380
Cdd:PRK13538 18 SGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGE---PIRRQRDEYHQ-------DLLYlghqpgikT 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 DLTVREHLDLYSAVKGLTKEEAALSVsrLAdALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEG 1460
Cdd:PRK13538 88 ELTALENLRFYQRLHGPGDDEALWEA--LA-QVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPLWILDEPFTAIDKQG 164
|
170 180
....*....|....*....|....*.
gi 1387227070 1461 QLQMwqaIQAIVKSSARG--ALLTTH 1484
Cdd:PRK13538 165 VARL---EALLAQHAEQGgmVILTTH 187
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
500-720 |
8.90e-20 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 92.87 E-value: 8.90e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 500 LQGICLDV---YEGQ-LTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQL---SEIINMEEIRNYTGFCPQFNIYFD 572
Cdd:TIGR02142 9 LGDFSLDAdftLPGQgVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLfdsRKGIFLPPEKRRIGYVFQEARLFP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 573 FLTVRENLRLfaKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFS 652
Cdd:TIGR02142 89 HLSVRGNLRY--GMKRARPSERRISFERVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPR 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 653 RHLVWNFLkERKTNHT---ILFSTQFMDEADILADRKVFLSNGKLRCAGSslfLKRKWGIGYHLSLHRNER 720
Cdd:TIGR02142 167 KYEILPYL-ERLHAEFgipILYVSHSLQEVLRLADRVVVLEDGRVAAAGP---IAEVWASPDLPWLAREDQ 233
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
478-694 |
9.69e-20 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 90.67 E-value: 9.69e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 478 KEAIRIRNLRKEYKGKpekvEALQGICLDVYEGQLTAILGHSGAGKSSLLSILG-----GWSACTEGSATIYNTQL-SEI 551
Cdd:PRK14267 2 KFAIETVNLRVYYGSN----HVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNrllelNEEARVEGEVRLFGRNIySPD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 552 INMEEIRNYTGFCPQFNIYFDFLTVRENLRLFAKIKGI--PPKEVEQEV-----KSIMMELDMHNIQDViAKELSGGQKR 624
Cdd:PRK14267 78 VDPIEVRREVGMVFQYPNPFPHLTIYDNVAIGVKLNGLvkSKKELDERVewalkKAALWDEVKDRLNDY-PSNLSGGQRQ 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 625 KLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:PRK14267 157 RLVIARALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKEYTIVLVTHSPAQAARVSDYVAFLYLGKL 226
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
496-702 |
1.04e-19 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 89.94 E-value: 1.04e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 496 KVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINMEEIRNYTGFCPQFNIYFDFLT 575
Cdd:PRK11614 17 KIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKIMREAVAIVPEGRRVFSRMT 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 576 VRENLRL---FAKikgippKEVEQE----VKSIMMELDMHNIQDviAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGL 648
Cdd:PRK11614 97 VEENLAMggfFAE------RDQFQErikwVYELFPRLHERRIQR--AGTMSGGEQQMLAIGRALMSQPRLLLLDEPSLGL 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 649 DPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGK--LRCAGSSLF 702
Cdd:PRK11614 169 APIIIQQIFDTIEQlREQGMTIFLVEQNANQALKLADRGYVLENGHvvLEDTGDALL 225
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
481-650 |
1.05e-19 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 90.92 E-value: 1.05e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKE-YKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYN---TQLSEiinmEE 556
Cdd:COG1101 2 LELKNLSKTfNPGTVNEKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGkdvTKLPE----YK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 557 IRNY---------TGFCPQfniyfdfLTVRENLRLFAK-------IKGIPPKEVEQ---EVKSimMELDMHNIQDVIAKE 617
Cdd:COG1101 78 RAKYigrvfqdpmMGTAPS-------MTIEENLALAYRrgkrrglRRGLTKKRRELfreLLAT--LGLGLENRLDTKVGL 148
|
170 180 190
....*....|....*....|....*....|...
gi 1387227070 618 LSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDP 650
Cdd:COG1101 149 LSGGQRQALSLLMATLTKPKLLLLDEHTAALDP 181
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
481-671 |
1.05e-19 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 92.04 E-value: 1.05e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSL-LSILG--GWSACTEGSATIYNTQLSEIIN--ME 555
Cdd:COG0444 2 LEVRNLKVYFPTRRGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLaRAILGllPPPGITSGEILFDGEDLLKLSEkeLR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 556 EIRN----------YTGFCPQFNIYFdflTVRENLRLFakiKGIPPKEVEQEVKSIMMELDMHNIQDVIAK---ELSGGQ 622
Cdd:COG0444 82 KIRGreiqmifqdpMTSLNPVMTVGD---QIAEPLRIH---GGLSKAEARERAIELLERVGLPDPERRLDRyphELSGGM 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 623 KRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILF 671
Cdd:COG0444 156 RQRVMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDlqRELGLAILF 206
|
|
| cbiO |
TIGR01166 |
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ... |
494-679 |
1.11e-19 |
|
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 88.63 E-value: 1.11e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 494 PEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLS-EIINMEEIRNYTGFC---PQFNI 569
Cdd:TIGR01166 2 PGGPEVLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRPQSGAVLIDGEPLDySRKGLLERRQRVGLVfqdPDDQL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 570 YFDflTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLD 649
Cdd:TIGR01166 82 FAA--DVDQDVAFGPLNLGLSEAEVERRVREALTAVGASGLRERPTHCLSGGEKKRVAIAGAVAMRPDVLLLDEPTAGLD 159
|
170 180 190
....*....|....*....|....*....|.
gi 1387227070 650 PFSRHLVWNFLKE-RKTNHTILFSTQFMDEA 679
Cdd:TIGR01166 160 PAGREQMLAILRRlRAEGMTVVISTHDVDLA 190
|
|
| type_I_sec_LssB |
TIGR03375 |
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ... |
458-694 |
1.60e-19 |
|
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274550 [Multi-domain] Cd Length: 694 Bit Score: 94.93 E-value: 1.60e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 458 MNSELSCDDSFEPVSPEfHRKEAIRIRNLRKEYKGkpEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACT 537
Cdd:TIGR03375 442 MQLPVERPEGTRFLHRP-RLQGEIEFRNVSFAYPG--QETPALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPT 518
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 538 EGSATIYNTQLSEIiNMEEIRNYTGFCPQfNIYFDFLTVRENLRLF------------AKIKGippkeVEQEVKSIMMEL 605
Cdd:TIGR03375 519 EGSVLLDGVDIRQI-DPADLRRNIGYVPQ-DPRLFYGTLRDNIALGapyaddeeilraAELAG-----VTEFVRRHPDGL 591
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 606 DMhniqdVIAK---ELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTILFST---QFMDea 679
Cdd:TIGR03375 592 DM-----QIGErgrSLSGGQRQAVALARALLRDPPILLLDEPTSAMDNRSEERFKDRLKRWLAGKTLVLVThrtSLLD-- 664
|
250
....*....|....*
gi 1387227070 680 diLADRKVFLSNGKL 694
Cdd:TIGR03375 665 --LVDRIIVMDNGRI 677
|
|
| COG4674 |
COG4674 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
499-670 |
1.61e-19 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443710 [Multi-domain] Cd Length: 250 Bit Score: 89.79 E-value: 1.61e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 499 ALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTqlsEIINMEEIR-NYTGFCPQF---NIyFDFL 574
Cdd:COG4674 25 ALNDLSLYVDPGELRVIIGPNGAGKTTLMDVITGKTRPDSGSVLFGGT---DLTGLDEHEiARLGIGRKFqkpTV-FEEL 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 575 TVRENLRL--------FAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTA 646
Cdd:COG4674 101 TVFENLELalkgdrgvFASLFARLTAEERDRIEEVLETIGLTDKADRLAGLLSHGQKQWLEIGMLLAQDPKLLLLDEPVA 180
|
170 180
....*....|....*....|....
gi 1387227070 647 GLDPFSRHLVWNFLKERKTNHTIL 670
Cdd:COG4674 181 GMTDAETERTAELLKSLAGKHSVV 204
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
480-694 |
1.70e-19 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 89.69 E-value: 1.70e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGKpekvEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQ--LSEIINMEEI 557
Cdd:PRK11124 2 SIQLNGINCFYGAH----QALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHfdFSKTPSDKAI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 558 R----NYTGFCPQFNIYfDFLTVRENL-RLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAI 632
Cdd:PRK11124 78 RelrrNVGMVFQQYNLW-PHLTVQQNLiEAPCRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARAL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 633 LGDPQVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:PRK11124 157 MMEPQVLLFDEPTAALDPEITAQIVSIIRElAETGITQVIVTHEVEVARKTASRVVYMENGHI 219
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
1305-1459 |
1.79e-19 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 93.98 E-value: 1.79e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdsgtpptrqaGGGFRhLGYCPQE-DVLWPDLT 1383
Cdd:COG0488 328 KTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-----------GETVK-IGYFDQHqEELDPDKT 395
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 1384 VREHLDLYSavKGLTKEEAAlsvSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPE 1459
Cdd:COG0488 396 VLDELRDGA--PGGTEQEVR---GYLGRFLFSGDDAFKPVGVLSGGEKARLALAKLLLSPPNVLLLDEPTNHLDIE 466
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
1287-1504 |
2.33e-19 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 88.36 E-value: 2.33e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1287 LHKEYKqekkrcfsarkTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD-SGTPPTRQAGGG 1365
Cdd:cd03262 6 LHKSFG-----------DFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGlKLTDDKKNINEL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1366 FRHLGYCPQEDVLWPDLTVREHLDLysA---VKGLTKEEAalsvsrLADALKLQDQMALPAKA------LPEGAKRKLSF 1436
Cdd:cd03262 75 RQKVGMVFQQFNLFPHLTVLENITL--ApikVKGMSKAEA------EERALELLEKVGLADKAdaypaqLSGGQQQRVAI 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 1437 ALSVLGSPALLLLDEPTTGMDPEgqlqMWQAIQAIVKSSARGA---LLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:cd03262 147 ARALAMNPKVMLFDEPTSALDPE----LVGEVLDVMKDLAEEGmtmVVVTHEMGFAREVADRVIFMDDGRI 213
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
481-694 |
3.11e-19 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 90.53 E-value: 3.11e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEY-KGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSA------------------ 541
Cdd:PRK13651 3 IKVKNIVKIFnKKLPTELKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIewifkdeknkkktkekek 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 542 -----TIYNTQLSEIINMEEIRNYTGFCPQFNIYFDF-LTVRENLRLFAKIKGIPPKEVEQEVKSI--MMELDmhniQDV 613
Cdd:PRK13651 83 vleklVIQKTRFKKIKKIKEIRRRVGVVFQFAEYQLFeQTIEKDIIFGPVSMGVSKEEAKKRAAKYieLVGLD----ESY 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 614 IAK---ELSGGQKRKltfgIAILG----DPQVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADR 685
Cdd:PRK13651 159 LQRspfELSGGQKRR----VALAGilamEPDFLVFDEPTAGLDPQGVKEILEIFDNlNKQGKTIILVTHDLDNVLEWTKR 234
|
....*....
gi 1387227070 686 KVFLSNGKL 694
Cdd:PRK13651 235 TIFFKDGKI 243
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
483-673 |
3.20e-19 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 94.02 E-value: 3.20e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 483 IRNLRKEYKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiINMEEI----R 558
Cdd:PRK10535 7 LKDIRRSYPSGEEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVAT-LDADALaqlrR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 559 NYTGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQV 638
Cdd:PRK10535 86 EHFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQV 165
|
170 180 190
....*....|....*....|....*....|....*.
gi 1387227070 639 LLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFST 673
Cdd:PRK10535 166 ILADEPTGALDSHSGEEVMAILHQlRDRGHTVIIVT 201
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
478-694 |
3.59e-19 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 89.69 E-value: 3.59e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 478 KEAIRIRNLRKEYKGkpEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiINMEEI 557
Cdd:PRK13635 3 EEIIRVEHISFRYPD--AATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSE-ETVWDV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 558 RNYTGFCPQfNIYFDFL--TVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMhniQDVIAKE---LSGGQKRKltfgIAI 632
Cdd:PRK13635 80 RRQVGMVFQ-NPDNQFVgaTVQDDVAFGLENIGVPREEMVERVDQALRQVGM---EDFLNREphrLSGGQKQR----VAI 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 633 LG----DPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEAdILADRKVFLSNGKL 694
Cdd:PRK13635 152 AGvlalQPDIIILDEATSMLDPRGRREVLETVRQlkEQKGITVLSITHDLDEA-AQADRVIVMNKGEI 218
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
481-717 |
4.20e-19 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 89.52 E-value: 4.20e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYkgkPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLS-EIINMEEIRN 559
Cdd:PRK13636 6 LKVEELNYNY---SDGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIDySRKGLMKLRE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YTGFCPQF--NIYFDfLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQ 637
Cdd:PRK13636 83 SVGMVFQDpdNQLFS-ASVYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 638 VLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAG--SSLFLKRKWGIGYHL 713
Cdd:PRK13636 162 VLVLDEPTAGLDPMGVSEIMKLLVEmqKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGnpKEVFAEKEMLRKVNL 241
|
....
gi 1387227070 714 SLHR 717
Cdd:PRK13636 242 RLPR 245
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
481-699 |
4.43e-19 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 89.09 E-value: 4.43e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKpekVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRNY 560
Cdd:PRK13652 4 IETRDLCYSYSGS---KEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKE-NIREVRKF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFLTVRENLRLFAKIK-GIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVL 639
Cdd:PRK13652 80 VGLVFQNPDDQIFSPTVEQDIAFGPINlGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 640 LLDEPTAGLDPFSRHLVWNFLKERKTNH--TILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:PRK13652 160 VLDEPTAGLDPQGVKELIDFLNDLPETYgmTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGT 221
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
479-699 |
4.73e-19 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 90.29 E-value: 4.73e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 479 EAIRIRNLRKEYKGK-PEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEG----------------SA 541
Cdd:PRK13631 20 IILRVKNLYCVFDEKqENELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGtiqvgdiyigdkknnhEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 542 TIYNTQlSEIINMEEIRNYTGFCPQFNIYFDFLTVRENLRLFAKIK-GIPPKEVEQEVKS--IMMELDmHNIQDVIAKEL 618
Cdd:PRK13631 100 ITNPYS-KKIKNFKELRRRVSMVFQFPEYQLFKDTIEKDIMFGPVAlGVKKSEAKKLAKFylNKMGLD-DSYLERSPFGL 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 619 SGGQKRKltfgIAILG----DPQVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGK 693
Cdd:PRK13631 178 SGGQKRR----VAIAGilaiQPEILIFDEPTAGLDPKGEHEMMQLILDaKANNKTVFVITHTMEHVLEVADEVIVMDKGK 253
|
....*.
gi 1387227070 694 LRCAGS 699
Cdd:PRK13631 254 ILKTGT 259
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
481-650 |
5.31e-19 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 92.81 E-value: 5.31e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEkveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRNY 560
Cdd:TIGR02868 335 LELRDLSAGYPGAPP---VLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSL-DQDEVRRR 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDfLTVRENLRLFAKikGIPPKEVEQEVKSIMMELDM----HNIQDVI---AKELSGGQKRKLTFGIAIL 633
Cdd:TIGR02868 411 VSVCAQDAHLFD-TTVRENLRLARP--DATDEELWAALERVGLADWLralpDGLDTVLgegGARLSGGERQRLALARALL 487
|
170
....*....|....*..
gi 1387227070 634 GDPQVLLLDEPTAGLDP 650
Cdd:TIGR02868 488 ADAPILLLDEPTEHLDA 504
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
479-699 |
5.81e-19 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 88.29 E-value: 5.81e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 479 EAIRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiINMEEIR 558
Cdd:PRK13548 1 AMLEARNLSVRLGGRT----LLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLAD-WSPAELA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 559 NYTGFCPQ-FNIYFDFlTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQK------RKLTFGIA 631
Cdd:PRK13548 76 RRRAVLPQhSSLSFPF-TVEEVVAMGRAPHGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQqrvqlaRVLAQLWE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 632 ILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKT-------------NHTILFstqfmdeadilADRKVFLSNGKLRCAG 698
Cdd:PRK13548 155 PDGPPRWLLLDEPTSALDLAHQHHVLRLARQLAHerglavivvlhdlNLAARY-----------ADRIVLLHQGRLVADG 223
|
.
gi 1387227070 699 S 699
Cdd:PRK13548 224 T 224
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
516-679 |
6.01e-19 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 93.65 E-value: 6.01e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 516 LGHSGAGKSSLLSILGGWSACTEGSATIyntqLSEII---NMEeIRNYTGFCPQ-FNIYFDfLTVRENLRLFAKIKGIPP 591
Cdd:NF033858 298 LGSNGCGKSTTMKMLTGLLPASEGEAWL----FGQPVdagDIA-TRRRVGYMSQaFSLYGE-LTVRQNLELHARLFHLPA 371
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 592 KEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTI 669
Cdd:NF033858 372 AEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDMFWRLLIElsREDGVTI 451
|
170
....*....|
gi 1387227070 670 LFSTQFMDEA 679
Cdd:NF033858 452 FISTHFMNEA 461
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
1305-1510 |
7.07e-19 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 88.95 E-value: 7.07e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPT----------RQAGGGFRHLGYCPQ 1374
Cdd:PRK13637 20 KKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIII--DGVDITdkkvklsdirKKVGLVFQYPEYQLF 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1375 EDVLWPDLTvrehldlYSAVK-GLTKEEAALSVSRLADALKLqDQMALPAKA---LPEGAKRKLSFALSVLGSPALLLLD 1450
Cdd:PRK13637 98 EETIEKDIA-------FGPINlGLSEEEIENRVKRAMNIVGL-DYEDYKDKSpfeLSGGQKRRVAIAGVVAMEPKILILD 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1451 EPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSV 1510
Cdd:PRK13637 170 EPTAGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTP 229
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
1304-1453 |
7.72e-19 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 92.05 E-value: 7.72e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1304 TKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRdsgtpptrqagGGFRhLGYCPQEDVLWPDLT 1383
Cdd:COG0488 10 GRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIP-----------KGLR-IGYLPQEPPLDDDLT 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1384 VRE-----HLDLYSAVKGLTKEEAALSVS--RLADALKLQDQM------ALPAKA--------LPE------------GA 1430
Cdd:COG0488 78 VLDtvldgDAELRALEAELEELEAKLAEPdeDLERLAELQEEFealggwEAEARAeeilsglgFPEedldrpvselsgGW 157
|
170 180
....*....|....*....|...
gi 1387227070 1431 KRKLSFALSVLGSPALLLLDEPT 1453
Cdd:COG0488 158 RRRVALARALLSEPDLLLLDEPT 180
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
480-692 |
7.85e-19 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 90.29 E-value: 7.85e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGKpekVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNtqlsEIINMEEIR- 558
Cdd:PRK11650 3 GLKLQAVRKSYDGK---TQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGG----RVVNELEPAd 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 559 --------NYTGFcPQfniyfdfLTVRENLRLFAKIKGIPPKEVEQEVKSI--MMELDmhNIQDVIAKELSGGQKRKLTF 628
Cdd:PRK11650 76 rdiamvfqNYALY-PH-------MSVRENMAYGLKIRGMPKAEIEERVAEAarILELE--PLLDRKPRELSGGQRQRVAM 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 629 GIAILGDPQVLLLDEPTAGLDPFSR--------HLvwnflkERKTNHTILFSTQFMDEADILADRKVFLSNG 692
Cdd:PRK11650 146 GRAIVREPAVFLFDEPLSNLDAKLRvqmrleiqRL------HRRLKTTSLYVTHDQVEAMTLADRVVVMNGG 211
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
485-699 |
8.19e-19 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 87.64 E-value: 8.19e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 485 NLRKEYKGKpekvEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINMEEIRNYTGFC 564
Cdd:PRK10895 8 NLAKAYKGR----RVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHARARRGIGYL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 565 PQFNIYFDFLTVRENLRLFAKI-KGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDE 643
Cdd:PRK10895 84 PQEASIFRRLSVYDNLMAVLQIrDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDE 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 644 PTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:PRK10895 164 PFAGVDPISVIDIKRIIEHlRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGT 220
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
1303-1576 |
9.59e-19 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 88.25 E-value: 9.59e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1303 KTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAG-VVVFRDSGTPPT-----RQAGGGFRHlgycpqed 1376
Cdd:PRK13650 18 QEKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGqIIIDGDLLTEENvwdirHKIGMVFQN-------- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1377 vlwPD-----LTVREHLDLYSAVKGLTKEEAalsVSRLADALKLQDQMAL----PAKaLPEGAKRKLSFALSVLGSPALL 1447
Cdd:PRK13650 90 ---PDnqfvgATVEDDVAFGLENKGIPHEEM---KERVNEALELVGMQDFkerePAR-LSGGQKQRVAIAGAVAMRPKII 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1448 LLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAeAVCDRVAIMVSGRLRCIGSVQHLKSKfGKDyLLEvkv 1527
Cdd:PRK13650 163 ILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEV-ALSDRVLVMKNGQVESTSTPRELFSR-GND-LLQ--- 236
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 1387227070 1528 kaLTLVEPLHMEILklfpQAARQERYSFVMAYKLAIEDVHPLSQTFSKL 1576
Cdd:PRK13650 237 --LGLDIPFTTSLV----QSLRQNGYDLPEGYLTEKELEEQLWELISKM 279
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
480-689 |
1.16e-18 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 91.58 E-value: 1.16e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGKPEkveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRN 559
Cdd:TIGR02857 321 SLEFSGVSVAYPGRRP---ALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADA-DADSWRD 396
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YTGFCPQFNIYFDfLTVRENLRLFAKikGIPPKEVEQEVKSI-MMELD------MHNIQDVIAKELSGGQKRKLTFGIAI 632
Cdd:TIGR02857 397 QIAWVPQHPFLFA-GTIAENIRLARP--DASDAEIREALERAgLDEFVaalpqgLDTPIGEGGAGLSGGQAQRLALARAF 473
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 633 LGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTQfmDEADI-LADRKVFL 689
Cdd:TIGR02857 474 LRDAPLLLLDEPTAHLDAETEAEVLEALRALAQGRTVLLVTH--RLALAaLADRIVVL 529
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
1307-1508 |
1.30e-18 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 87.70 E-value: 1.30e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTRQAGGGFRHL-----GYCPQEDVLWPD 1381
Cdd:cd03294 39 GVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLI--DGQDIAAMSRKELRELrrkkiSMVFQSFALLPH 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 LTVREHLDLYSAVKGLTKEEaalsvsRLADALKLQDQMALPA------KALPEGAKRKLSFALSVLGSPALLLLDEPTTG 1455
Cdd:cd03294 117 RTVLENVAFGLEVQGVPRAE------REERAAEALELVGLEGwehkypDELSGGMQQRVGLARALAVDPDILLMDEAFSA 190
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 1456 MDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIG 1508
Cdd:cd03294 191 LDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVG 243
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
494-699 |
1.31e-18 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 88.25 E-value: 1.31e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 494 PEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYN---TQLSEIINMEEIRNYTGFCPQF--N 568
Cdd:PRK13643 16 PFASRALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDivvSSTSKQKEIKPVRKKVGVVFQFpeS 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 569 IYFDfLTVRENLRLFAKIKGIPPKEVEqevKSIMMELDMHNIQDVIAK----ELSGGQKRKLTFGIAILGDPQVLLLDEP 644
Cdd:PRK13643 96 QLFE-ETVLKDVAFGPQNFGIPKEKAE---KIAAEKLEMVGLADEFWEkspfELSGGQMRRVAIAGILAMEPEVLVLDEP 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 645 TAGLDPFSR-HLVWNFLKERKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:PRK13643 172 TAGLDPKARiEMMQLFESIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGT 227
|
|
| potA |
TIGR01187 |
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ... |
515-700 |
2.15e-18 |
|
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 88.32 E-value: 2.15e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 515 ILGHSGAGKSSLLSILGGWSACTEGSATIYNTqlsEIINMEEIRNYTGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEV 594
Cdd:TIGR01187 1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGE---DVTNVPPHLRHINMVFQSYALFPHMTVEENVAFGLKMRKVPRAEI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 595 EQEVKSImmeLDMHNIQDVIAK---ELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLK--ERKTNHTI 669
Cdd:TIGR01187 78 KPRVLEA---LRLVQLEEFADRkphQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKtiQEQLGITF 154
|
170 180 190
....*....|....*....|....*....|.
gi 1387227070 670 LFSTQFMDEADILADRKVFLSNGKLRCAGSS 700
Cdd:TIGR01187 155 VFVTHDQEEAMTMSDRIAIMRKGKIAQIGTP 185
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
1272-1519 |
2.40e-18 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 90.88 E-value: 2.40e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1272 LTASSLDEPVIMASCLHKEYKQEKKRCFSA----RKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGdtKPTAG 1347
Cdd:TIGR00955 1 LTYSWRNSDVFGRVAQDGSWKQLVSRLRGCfcreRPRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAF--RSPKG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1348 VVVFRD---SGTPPTRQAgggFRHL-GYCPQEDVLWPDLTVREHLDLYSAVK---GLTKEEAALSVSRLADALKLQD--- 1417
Cdd:TIGR00955 79 VKGSGSvllNGMPIDAKE---MRAIsAYVQQDDLFIPTLTVREHLMFQAHLRmprRVTKKEKRERVDEVLQALGLRKcan 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1418 ---QMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKsSARGALLTTHS-MAEAEAVC 1493
Cdd:TIGR00955 156 triGVPGRVKGLSGGERKRLAFASELLTDPPLLFCDEPTSGLDSFMAYSVVQVLKGLAQ-KGKTIICTIHQpSSELFELF 234
|
250 260
....*....|....*....|....*.
gi 1387227070 1494 DRVAIMVSGRLRCIGSVQHLKSKFGK 1519
Cdd:TIGR00955 235 DKIILMAEGRVAYLGSPDQAVPFFSD 260
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
1304-1509 |
2.46e-18 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 86.72 E-value: 2.46e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1304 TKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAG-VVVF-RDSGTPPT-----RQAGGGFRHlgycpqed 1376
Cdd:TIGR04520 14 EKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGkVTVDgLDTLDEENlweirKKVGMVFQN-------- 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1377 vlwPD-----LTVREhlDlysaV------KGLTKEEAalsVSRLADALK---LQDQMALPAKALPEGAKRKLSFAlSVLG 1442
Cdd:TIGR04520 86 ---PDnqfvgATVED--D----VafglenLGVPREEM---RKRVDEALKlvgMEDFRDREPHLLSGGQKQRVAIA-GVLA 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 1443 -SPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAeAVCDRVAIMVSGRLRCIGS 1509
Cdd:TIGR04520 153 mRPDIIILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEA-VLADRVIVMNKGKIVAEGT 219
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
1307-1518 |
2.84e-18 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 88.25 E-value: 2.84e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAG--KSTCIKMITGdtkPTAGVVVFRDSGTPPTRQAGGgfRHLG-YCPQEDVLWPDLT 1383
Cdd:NF000106 28 AVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*G---PDAGRRPWRF*TWCANRRALR--RTIG*HRPVR*GRRESFS 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1384 VREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQ 1463
Cdd:NF000106 103 GRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNE 182
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 1464 MWQAIQAIVKSSARgALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLKSKFG 1518
Cdd:NF000106 183 VWDEVRSMVRDGAT-VLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVG 236
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
481-693 |
3.04e-18 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 88.74 E-value: 3.04e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEI------INM 554
Cdd:PRK11607 20 LEIRNLTKSFDGQH----AVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVppyqrpINM 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 555 eeirnytgfcpQFNIY--FDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAI 632
Cdd:PRK11607 96 -----------MFQSYalFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSL 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 633 LGDPQVLLLDEPTAGLDPFSR----HLVWNFLKerKTNHTILFSTQFMDEADILADRKVFLSNGK 693
Cdd:PRK11607 165 AKRPKLLLLDEPMGALDKKLRdrmqLEVVDILE--RVGVTCVMVTHDQEEAMTMAGRIAIMNRGK 227
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
481-694 |
3.33e-18 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 86.12 E-value: 3.33e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKgkpeKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGW-----SACTEGSATIYNtqlSEIINME 555
Cdd:PRK14247 4 IEIRDLKVSFG----QVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLielypEARVSGEVYLDG---QDIFKMD 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 556 --EIRNYTGFCPQFNIYFDFLTVRENLRLFAKIKGI--PPKEVEQEVKSIMMEL----DMHNIQDVIAKELSGGQKRKLT 627
Cdd:PRK14247 77 viELRRRVQMVFQIPNPIPNLSIFENVALGLKLNRLvkSKKELQERVRWALEKAqlwdEVKDRLDAPAGKLSGGQQQRLC 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 628 FGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:PRK14247 157 IARALAFQPEVLLADEPTANLDPENTAKIESLFLELKKDMTIVLVTHFPQQAARISDYVAFLYKGQI 223
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
481-698 |
3.35e-18 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 86.34 E-value: 3.35e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGkpEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSaTIYNTQLSEIINMEEIRNY 560
Cdd:PRK13648 8 IVFKNVSFQYQS--DASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGE-IFYNNQAITDDNFEKLRKH 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQfNIYFDFL--TVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKltfgIAILG---- 634
Cdd:PRK13648 85 IGIVFQ-NPDNQFVgsIVKYDVAFGLENHAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQR----VAIAGvlal 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 635 DPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNH--TILFSTQFMDEAdILADRKVFLSNGKLRCAG 698
Cdd:PRK13648 160 NPSVIILDEATSMLDPDARQNLLDLVRKVKSEHniTIISITHDLSEA-MEADHVIVMNKGTVYKEG 224
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
1287-1504 |
3.92e-18 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 87.42 E-value: 3.92e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1287 LHKEYKQEkkrcfsaRKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKP---TAGVVVFRdsGTPPTRQAG 1363
Cdd:COG0444 7 LKVYFPTR-------RGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPpgiTSGEILFD--GEDLLKLSE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1364 GGFRHL-----GYCPQE--DVLWPDLTVREHL-DLYSAVKGLTKEEAalsvsrLADALKLQDQMALPAkalPEGAKRK-- 1433
Cdd:COG0444 78 KELRKIrgreiQMIFQDpmTSLNPVMTVGDQIaEPLRIHGGLSKAEA------RERAIELLERVGLPD---PERRLDRyp 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1434 --LS--------FALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGR 1503
Cdd:COG0444 149 heLSggmrqrvmIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGR 228
|
.
gi 1387227070 1504 L 1504
Cdd:COG0444 229 I 229
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
481-694 |
3.95e-18 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 85.35 E-value: 3.95e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKgkpEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRNY 560
Cdd:cd03254 3 IEFENVNFSYD---EKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDI-SRKSLRSM 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFlTVRENLRLFAKIkgIPPKEVEQEVKSI-MMELDMHNIQ--DVIAKE----LSGGQKRKLTFGIAIL 633
Cdd:cd03254 79 IGVVLQDTFLFSG-TIMENIRLGRPN--ATDEEVIEAAKEAgAHDFIMKLPNgyDTVLGEnggnLSQGERQLLAIARAML 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 634 GDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTIL-----FSTqfmdeadIL-ADRKVFLSNGKL 694
Cdd:cd03254 156 RDPKILILDEATSNIDTETEKLIQEALEKLMKGRTSIiiahrLST-------IKnADKILVLDDGKI 215
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1305-1503 |
4.53e-18 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 85.91 E-value: 4.53e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPTRQAgggfRHLGYCPQEDVL--W 1379
Cdd:COG1101 19 KRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGkdvTKLPEYKRA----KYIGRVFQDPMMgtA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1380 PDLTVREHLDL-------YSAVKGLTKEEAALSVSRLAD-ALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDE 1451
Cdd:COG1101 95 PSMTIEENLALayrrgkrRGLRRGLTKKRRELFRELLATlGLGLENRLDTKVGLLSGGQRQALSLLMATLTKPKLLLLDE 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 1452 PTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGR 1503
Cdd:COG1101 175 HTAALDPKTAALVLELTEKIVEENNLTTLMVTHNMEQALDYGNRLIMMHEGR 226
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
1308-1510 |
4.85e-18 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 85.21 E-value: 4.85e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1308 VRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRdsGTPPTRQagGGFRHLGYcpQEDVLWPDLTVREH 1387
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILE--GKQITEP--GPDRMVVF--QNYSLLPWLTVREN 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1388 LDLY--SAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDP--EGQLQ 1463
Cdd:TIGR01184 75 IALAvdRVLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDAltRGNLQ 154
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1387227070 1464 mwQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSV 1510
Cdd:TIGR01184 155 --EELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNGPAANIGQI 199
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
1305-1511 |
5.62e-18 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 85.55 E-value: 5.62e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPTRQAgggfRHLGYCPQEDVLWPD 1381
Cdd:COG4559 14 RTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGrplAAWSPWELA----RRRAVLPQHSSLAFP 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 LTVRE--------HLDLYSAVKGLTkeEAALsvsRLADALKLQDQMALpakALPEGAKRKLSFA--L-----SVLGSPAL 1446
Cdd:COG4559 90 FTVEEvvalgrapHGSSAAQDRQIV--REAL---ALVGLAHLAGRSYQ---TLSGGEQQRVQLArvLaqlwePVDGGPRW 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 1447 LLLDEPTTGMDPEGQLQMWQaiqaIVKSSAR---GALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQ 1511
Cdd:COG4559 162 LFLDEPTSALDLAHQHAVLR----LARQLARrggGVVAVLHDLNLAAQYADRILLLHQGRLVAQGTPE 225
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
1306-1510 |
5.76e-18 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 89.32 E-value: 5.76e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1306 TAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPPT-----RQAGggfrhLGYCPQEDVLWP 1380
Cdd:COG3845 19 VANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRIRsprdaIALG-----IGMVHQHFMLVP 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 DLTVREHLDLYSAVKG---LTKEEAALSVSRLADALKLQ---DQMA--LPA---------KALPEGAKrklsfalsvlgs 1443
Cdd:COG3845 94 NLTVAENIVLGLEPTKggrLDRKAARARIRELSERYGLDvdpDAKVedLSVgeqqrveilKALYRGAR------------ 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 1444 paLLLLDEPTTGMDPegqlqmwQAIQ---AIVKS-SARGA--LLTTHSMAEAEAVCDRVAIMVSGRLrcIGSV 1510
Cdd:COG3845 162 --ILILDEPTAVLTP-------QEADelfEILRRlAAEGKsiIFITHKLREVMAIADRVTVLRRGKV--VGTV 223
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
481-699 |
6.19e-18 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 84.47 E-value: 6.19e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKgkPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiINMEEIRNY 560
Cdd:cd03244 3 IEFKNVSLRYR--PNLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISK-IGLHDLRSR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFlTVRENL---------RLFAKIKGIPPKEVeqeVKSIMMELDMhniqDVIA--KELSGGQKRKLTFG 629
Cdd:cd03244 80 ISIIPQDPVLFSG-TIRSNLdpfgeysdeELWQALERVGLKEF---VESLPGGLDT----VVEEggENLSVGQRQLLCLA 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1387227070 630 IAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTQ----FMDeadilADRKVFLSNGKLRCAGS 699
Cdd:cd03244 152 RALLRKSKILVLDEATASVDPETDALIQKTIREAFKDCTVLTIAHrldtIID-----SDRILVLDKGRVVEFDS 220
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
1306-1499 |
6.41e-18 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 83.44 E-value: 6.41e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1306 TAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVvfrdsgtpptRQAGGgfRHLGYCPQEDVLwPD---L 1382
Cdd:NF040873 6 PVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTV----------RRAGG--ARVAYVPQRSEV-PDslpL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1383 TVREHLDL-----YSAVKGLTKEEAAlSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMD 1457
Cdd:NF040873 73 TVRDLVAMgrwarRGLWRRLTRDDRA-AVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLD 151
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1387227070 1458 PEGQLQMWQAIQAIVkssARGA--LLTTHSMAEAEAVcDRVAIM 1499
Cdd:NF040873 152 AESRERIIALLAEEH---ARGAtvVVVTHDLELVRRA-DPCVLL 191
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
1305-1503 |
7.50e-18 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 84.54 E-value: 7.50e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTRQAGGGFR----HLGYCPQEDVLWP 1380
Cdd:cd03256 14 KKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLI--DGTDINKLKGKALRqlrrQIGMIFQQFNLIE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 DLTVREH-----LDLYSAVKGL----TKEEAALSVSRLaDALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDE 1451
Cdd:cd03256 92 RLSVLENvlsgrLGRRSTWRSLfglfPKEEKQRALAAL-ERVGLLDKAYQRADQLSGGQQQRVAIARALMQQPKLILADE 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 1452 PTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGR 1503
Cdd:cd03256 171 PVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGR 222
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
484-662 |
8.08e-18 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 84.48 E-value: 8.08e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 484 RNLRKEYKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEI--INMEEIRNYT 561
Cdd:PRK11629 9 DNLCKRYQEGSVQTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLssAAKAELRNQK 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 562 -GFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLL 640
Cdd:PRK11629 89 lGFIYQFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVL 168
|
170 180
....*....|....*....|..
gi 1387227070 641 LDEPTAGLDPFSRHLVWNFLKE 662
Cdd:PRK11629 169 ADEPTGNLDARNADSIFQLLGE 190
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
1301-1484 |
8.30e-18 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 83.70 E-value: 8.30e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1301 ARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTRQAGGGFRHLGYCPQEDVLWP 1380
Cdd:cd03231 9 ERDGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLL--NGGPLDFQRDSIARGLLYLGHAPGIKT 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 DLTVREHLDLYSAVKGLTKEEAALSVSRLAdalKLQDqmaLPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEG 1460
Cdd:cd03231 87 TLSVLENLRFWHADHSDEQVEEALARVGLN---GFED---RPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAG 160
|
170 180
....*....|....*....|....*.
gi 1387227070 1461 QLQMWQAIQAivkSSARG--ALLTTH 1484
Cdd:cd03231 161 VARFAEAMAG---HCARGgmVVLTTH 183
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
1306-1509 |
1.10e-17 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 84.31 E-value: 1.10e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1306 TAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF--RDSGTPPTRQagggfRHLGYCPQEDVLWPDLT 1383
Cdd:cd03296 16 VALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFggEDATDVPVQE-----RNVGFVFQHYALFRHMT 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1384 VREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPE---GAKRK---LSFALSVlgSPALLLLDEPTTGMD 1457
Cdd:cd03296 91 VFDNVAFGLRVKPRSERPPEAEIRAKVHELLKLVQLDWLADRYPAqlsGGQRQrvaLARALAV--EPKVLLLDEPFGALD 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1387227070 1458 PE--GQLQMWqaIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGS 1509
Cdd:cd03296 169 AKvrKELRRW--LRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGT 220
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
480-694 |
1.62e-17 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 87.77 E-value: 1.62e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGkpekVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGsaTIYntqlseiINMEEIRN 559
Cdd:COG1129 4 LLEMRGISKSFGG----VKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSG--EIL-------LDGEPVRF 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YT---------GFCPQ-FNIyFDFLTVRENL---RLFAKIKGIPPKEVEQEVKSIMMELDMHnIQ-DVIAKELSGGQK-- 623
Cdd:COG1129 71 RSprdaqaagiAIIHQeLNL-VPNLSVAENIflgREPRRGGLIDWRAMRRRARELLARLGLD-IDpDTPVGDLSVAQQql 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 624 ----RkltfgiAILGDPQVLLLDEPTAGLDPF-SRHLvwnF-----LKERKTnhTILFSTQFMDEADILADRKVFLSNGK 693
Cdd:COG1129 149 veiaR------ALSRDARVLILDEPTASLTEReVERL---FriirrLKAQGV--AIIYISHRLDEVFEIADRVTVLRDGR 217
|
.
gi 1387227070 694 L 694
Cdd:COG1129 218 L 218
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
479-692 |
2.18e-17 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 82.87 E-value: 2.18e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 479 EAIRIRNLRKEYK-----GKpeKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYN-------T 546
Cdd:COG4778 3 TLLEVENLSKTFTlhlqgGK--RLPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHdggwvdlA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 547 QLS--EIInmeEIRNYT-GFCPQFniyfdfLTVR----------ENLRLfakiKGIPPKEVEQEVKSIMMELDmhniqdv 613
Cdd:COG4778 81 QASprEIL---ALRRRTiGYVSQF------LRVIprvsaldvvaEPLLE----RGVDREEARARARELLARLN------- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 614 IAKEL--------SGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTqFMDEA--DILA 683
Cdd:COG4778 141 LPERLwdlppatfSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKARGTAIIGI-FHDEEvrEAVA 219
|
....*....
gi 1387227070 684 DRKVFLSNG 692
Cdd:COG4778 220 DRVVDVTPF 228
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
1307-1503 |
2.59e-17 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 83.50 E-value: 2.59e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDS---GTPPTRQAGGG----FRHLGYCPQEDVLw 1379
Cdd:PRK11300 20 AVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQhieGLPGHQIARMGvvrtFQHVRLFREMTVI- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1380 PDLTVREHLDLYSAV-KGLTKEEAAlsvsRLADALKLQ------DQMAL------PAKALPEGAKRKLSFALSVLGSPAL 1446
Cdd:PRK11300 99 ENLLVAQHQQLKTGLfSGLLKTPAF----RRAESEALDraatwlERVGLlehanrQAGNLAYGQQRRLEIARCMVTQPEI 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 1447 LLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGR 1503
Cdd:PRK11300 175 LMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGT 231
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
480-692 |
4.47e-17 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 82.83 E-value: 4.47e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNtqlseiINMEEIRN 559
Cdd:PRK11248 1 MLQISHLYADYGGKP----ALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDG------KPVEGPGA 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YTGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVL 639
Cdd:PRK11248 71 ERGVVFQNEGLLPWRNVQDNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLL 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 640 LLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNG 692
Cdd:PRK11248 151 LLDEPFGALDAFTREQMQTLLLKlwQETGKQVLLITHDIEEAVFMATELVLLSPG 205
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
480-699 |
5.24e-17 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 84.75 E-value: 5.24e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYkgkpEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINMEeiRN 559
Cdd:PRK10851 2 SIEIANIKKSF----GRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARD--RK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 yTGFCPQFNIYFDFLTVREN----LRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGD 635
Cdd:PRK10851 76 -VGFVFQHYALFRHMTVFDNiafgLTVLPRRERPNAAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVE 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 636 PQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:PRK10851 155 PQILLLDEPFGALDAQVRKELRRWLRQlhEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGT 220
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
480-699 |
5.45e-17 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 83.31 E-value: 5.45e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGKPEKveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGW---SACTEGSATIYNTQLSEIiNMEE 556
Cdd:PRK13640 5 IVEFKHVSFTYPDSKKP--ALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLllpDDNPNSKITVDGITLTAK-TVWD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 557 IRNYTGFCPQfNIYFDFL--TVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKltfgIAILG 634
Cdd:PRK13640 82 IREKVGIVFQ-NPDNQFVgaTVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQR----VAIAG 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 635 ----DPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADiLADRKVFLSNGKLRCAGS 699
Cdd:PRK13640 157 ilavEPKIIILDESTSMLDPAGKEQILKLIRKlkKKNNLTVISITHDIDEAN-MADQVLVLDDGKLLAQGS 226
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
1287-1510 |
5.85e-17 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 84.08 E-value: 5.85e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1287 LHKEYKQekkrcfsARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAG-VVV--------------- 1350
Cdd:PRK11153 7 ISKVFPQ-------GGRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGrVLVdgqdltalsekelrk 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1351 FRdsgtpptRQAGGGFRHLGycpqedvLWPDLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQM-ALPAKaLPEG 1429
Cdd:PRK11153 80 AR-------RQIGMIFQHFN-------LLSSRTVFDNVALPLELAGTPKAEIKARVTELLELVGLSDKAdRYPAQ-LSGG 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1430 AKRKLSFALSVLGSPALLLLDEPTTGMDPEGQlqmwQAIQAIVKSSAR----GALLTTHSMAEAEAVCDRVAIMVSGRLR 1505
Cdd:PRK11153 145 QKQRVAIARALASNPKVLLCDEATSALDPATT----RSILELLKDINRelglTIVLITHEMDVVKRICDRVAVIDAGRLV 220
|
....*
gi 1387227070 1506 CIGSV 1510
Cdd:PRK11153 221 EQGTV 225
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
1298-1523 |
6.19e-17 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 82.93 E-value: 6.19e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1298 CFSARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRdsGTPPTRQ--------AGGGFRHl 1369
Cdd:PRK13652 10 CYSYSGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIR--GEPITKEnirevrkfVGLVFQN- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1370 gycPQEDVLWPdlTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLL 1449
Cdd:PRK13652 87 ---PDDQIFSP--TVEQDIAFGPINLGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVL 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1387227070 1450 DEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLkskFGKDYLL 1523
Cdd:PRK13652 162 DEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEI---FLQPDLL 232
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
1307-1542 |
6.28e-17 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 82.97 E-value: 6.28e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTRQAGGGF---RHLGYCPQEdvlwPD-- 1381
Cdd:PRK13636 21 ALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILF--DGKPIDYSRKGLMklrESVGMVFQD----PDnq 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 ---LTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDP 1458
Cdd:PRK13636 95 lfsASVYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDP 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1459 EGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLKSKfgKDYLLEVKVKaLTLVEPLhM 1538
Cdd:PRK13636 175 MGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVFAE--KEMLRKVNLR-LPRIGHL-M 250
|
....
gi 1387227070 1539 EILK 1542
Cdd:PRK13636 251 EILK 254
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
481-694 |
7.19e-17 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 82.86 E-value: 7.19e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEKVeALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRNY 560
Cdd:PRK13650 5 IEVKNLTFKYKEDQEKY-TLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEE-NVWDIRHK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQfNIYFDFL--TVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQV 638
Cdd:PRK13650 83 IGMVFQ-NPDNQFVgaTVEDDVAFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKI 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 639 LLLDEPTAGLDPFSRHLVWNFLKERKTNH--TILFSTQFMDEAdILADRKVFLSNGKL 694
Cdd:PRK13650 162 IILDEATSMLDPEGRLELIKTIKGIRDDYqmTVISITHDLDEV-ALSDRVLVMKNGQV 218
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
1307-1504 |
7.50e-17 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 81.98 E-value: 7.50e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVV-----FRDSGTPPTRQAGGGFRHLGYCPQEDVLWPD 1381
Cdd:COG4161 17 ALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNiaghqFDFSQKPSEKAIRLLRQKVGMVFQQYNLWPH 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 LTVREHLdLYSAVK--GLTKEEAALSVSRLADALKLQDQM-ALPAkALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDP 1458
Cdd:COG4161 97 LTVMENL-IEAPCKvlGLSKEQAREKAMKLLARLRLTDKAdRFPL-HLSGGQQQRVAIARALMMEPQVLLFDEPTAALDP 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1387227070 1459 EGQLQmwqaIQAIVKS-SARG--ALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:COG4161 175 EITAQ----VVEIIRElSQTGitQVIVTHEVEFARKVASQVVYMEKGRI 219
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
1279-1513 |
8.96e-17 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 82.37 E-value: 8.96e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1279 EPVIMASCLHKEYKQEKKRcfsarktktAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVV-VFRDSGTP 1357
Cdd:PRK13635 3 EEIIRVEHISFRYPDAATY---------ALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTItVGGMVLSE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1358 PT-----RQAGGGFRHlgycpqedvlwPD-----LTVREHLDLYSAVKGLTKEEAalsVSRLADALKL---QDQMALPAK 1424
Cdd:PRK13635 74 ETvwdvrRQVGMVFQN-----------PDnqfvgATVQDDVAFGLENIGVPREEM---VERVDQALRQvgmEDFLNREPH 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1425 ALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAeAVCDRVAIMVSGRL 1504
Cdd:PRK13635 140 RLSGGQKQRVAIAGVLALQPDIIILDEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEA-AQADRVIVMNKGEI 218
|
....*....
gi 1387227070 1505 RCIGSVQHL 1513
Cdd:PRK13635 219 LEEGTPEEI 227
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
1299-1499 |
9.29e-17 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 85.42 E-value: 9.29e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1299 FSARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPPTRQAGGGfRHLGYCPQEDVL 1378
Cdd:TIGR02857 329 VAYPGRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADSWR-DQIAWVPQHPFL 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1379 WPDlTVREHLDLYsavkglTKEEAALSVSRLADALKLQDQM-ALPA----------KALPEGAKRKLSFALSVLGSPALL 1447
Cdd:TIGR02857 408 FAG-TIAENIRLA------RPDASDAEIREALERAGLDEFVaALPQgldtpigeggAGLSGGQAQRLALARAFLRDAPLL 480
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 1448 LLDEPTTGMDPEGQLQMWQAIQAIvkSSARGALLTTHSMAEAEAvCDRVAIM 1499
Cdd:TIGR02857 481 LLDEPTAHLDAETEAEVLEALRAL--AQGRTVLLVTHRLALAAL-ADRIVVL 529
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
481-701 |
9.80e-17 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 85.62 E-value: 9.80e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKpekvEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSAC--TEGSaTIYNTQLSEIINMEEIR 558
Cdd:TIGR03269 1 IEVKNLTKKFDGK----EVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQYepTSGR-IIYHVALCEKCGYVERP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 559 NYTGF-CPQFN-----IYFDFL----TVRENL---------RLFA----------KIKGIPPKEVEQEvKSIMMELDM-- 607
Cdd:TIGR03269 76 SKVGEpCPVCGgtlepEEVDFWnlsdKLRRRIrkriaimlqRTFAlygddtvldnVLEALEEIGYEGK-EAVGRAVDLie 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 608 -----HNIQDvIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEAD 680
Cdd:TIGR03269 155 mvqlsHRITH-IARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEavKASGISMVLTSHWPEVIE 233
|
250 260
....*....|....*....|.
gi 1387227070 681 ILADRKVFLSNGKLRCAGSSL 701
Cdd:TIGR03269 234 DLSDKAIWLENGEIKEEGTPD 254
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
500-655 |
1.18e-16 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 80.30 E-value: 1.18e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 500 LQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATiYNTQLSEIINMEEIRNYTG---FCPqfniyfDFLTV 576
Cdd:PRK13539 18 FSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIK-LDGGDIDDPDVAEACHYLGhrnAMK------PALTV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 577 RENLRLFAKIKGIPPKEVEQEVKSImmelDMHNIQDVIAKELSGGQKRKLtfGIAIL---GDPqVLLLDEPTAGLDP--- 650
Cdd:PRK13539 91 AENLEFWAAFLGGEELDIAAALEAV----GLAPLAHLPFGYLSAGQKRRV--ALARLlvsNRP-IWILDEPTAALDAaav 163
|
170
....*....|.
gi 1387227070 651 ------FSRHL 655
Cdd:PRK13539 164 alfaelIRAHL 174
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
1304-1503 |
1.50e-16 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 80.81 E-value: 1.50e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1304 TKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD-SGTPPTRQAGGGFRHLGYCPQEDVLWPDL 1382
Cdd:COG1126 13 DLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGeDLTDSKKDINKLRRKVGMVFQQFNLFPHL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1383 TVREHLDLysA---VKGLTKEEAalsvsrLADALKLQDQMALPAKA--LPegakRKLS----------FALSVlgSPALL 1447
Cdd:COG1126 93 TVLENVTL--ApikVKKMSKAEA------EERAMELLERVGLADKAdaYP----AQLSggqqqrvaiaRALAM--EPKVM 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 1448 LLDEPTTGMDPEgqlqMWQAIQAIVKSSARGA---LLTTHSMAEAEAVCDRVAIMVSGR 1503
Cdd:COG1126 159 LFDEPTSALDPE----LVGEVLDVMRDLAKEGmtmVVVTHEMGFAREVADRVVFMDGGR 213
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
1301-1513 |
1.62e-16 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 80.30 E-value: 1.62e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1301 ARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITG-----DTKPTAGVVVFRDSGTpptrqagggfrhlgYCPQE 1375
Cdd:cd03260 9 YYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRlndliPGAPDEGEVLLDGKDI--------------YDLDV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1376 DVLW-----------P---DLTVREHLDLYSAVKGLtKEEAALSvSRLADALK---LQDQMA--LPAKALPEGAKRKLSF 1436
Cdd:cd03260 75 DVLElrrrvgmvfqkPnpfPGSIYDNVAYGLRLHGI-KLKEELD-ERVEEALRkaaLWDEVKdrLHALGLSGGQQQRLCL 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 1437 ALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSsaRGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHL 1513
Cdd:cd03260 153 ARALANEPEVLLLDEPTSALDPISTAKIEELIAELKKE--YTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
481-699 |
1.83e-16 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 81.57 E-value: 1.83e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYkgkPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINMEEIRNY 560
Cdd:PRK13644 2 IRLENVSYSY---PDGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFSKLQGIRKL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQfNIYFDFL--TVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQV 638
Cdd:PRK13644 79 VGIVFQ-NPETQFVgrTVEEDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPEC 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 639 LLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADIlADRKVFLSNGKLRCAGS 699
Cdd:PRK13644 158 LIFDEVTSMLDPDSGIAVLERIKKlHEKGKTIVYITHNLEELHD-ADRIIVMDRGKIVLEGE 218
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
1299-1519 |
1.94e-16 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 81.27 E-value: 1.94e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1299 FSARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRdsGTPPT---RQAGGGFRH------- 1368
Cdd:PRK10419 19 SGKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWR--GEPLAklnRAQRKAFRRdiqmvfq 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1369 --LG-YCPQEDVLWpdlTVRE---HLdlysavKGLTKEEAALSVSRLADALKLQDQMA--LPAKaLPEGAKRKLSFALSV 1440
Cdd:PRK10419 97 dsISaVNPRKTVRE---IIREplrHL------LSLDKAERLARASEMLRAVDLDDSVLdkRPPQ-LSGGQLQRVCLARAL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1441 LGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRL---RCIGSVQHLKSKF 1517
Cdd:PRK10419 167 AVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIvetQPVGDKLTFSSPA 246
|
..
gi 1387227070 1518 GK 1519
Cdd:PRK10419 247 GR 248
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
481-693 |
1.95e-16 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 80.18 E-value: 1.95e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPekveaLQgICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNtqlseiinmeeiRNY 560
Cdd:COG3840 2 LRLDDLTYRYGDFP-----LR-FDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNG------------QDL 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCP---------QFNIYFDFLTVRENLRLfakikGIPPK-----EVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKL 626
Cdd:COG3840 64 TALPPaerpvsmlfQENNLFPHLTVAQNIGL-----GLRPGlkltaEQRAQVEQALERVGLAGLLDRLPGQLSGGQRQRV 138
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 627 TFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGK 693
Cdd:COG3840 139 ALARCLVRKRPILLLDEPFSALDPALRQEMLDLVDElcRERGLTVLMVTHDPEDAARIADRVLLVADGR 207
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
1304-1509 |
2.26e-16 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 83.07 E-value: 2.26e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1304 TKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPTRqagggfRHLGYCPQEDVLWP 1380
Cdd:PRK09452 26 GKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGqdiTHVPAEN------RHVNTVFQSYALFP 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 DLTVREHLDLYSAVKGLTKEEAAlsvSRLADALKL--QDQMA--LPAKaLPEGAKRKLSFALSVLGSPALLLLDEPTTGM 1456
Cdd:PRK09452 100 HMTVFENVAFGLRMQKTPAAEIT---PRVMEALRMvqLEEFAqrKPHQ-LSGGQQQRVAIARAVVNKPKVLLLDESLSAL 175
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 1457 DPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGS 1509
Cdd:PRK09452 176 DYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGT 228
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
478-694 |
2.45e-16 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 84.08 E-value: 2.45e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 478 KEAIRIRNLRKEY----KGKpekVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSatiYNTQL-SEII 552
Cdd:TIGR03269 277 EPIIKVRNVSKRYisvdRGV---VKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGE---VNVRVgDEWV 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 553 NMEEIR--------NYTGFCPQFNIYFDFLTVRENL---------RLFAKIKGIPPKEV----EQEVKSIMmeldmhniq 611
Cdd:TIGR03269 351 DMTKPGpdgrgrakRYIGILHQEYDLYPHRTVLDNLteaiglelpDELARMKAVITLKMvgfdEEKAEEIL--------- 421
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 612 DVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWN-FLKERKT-NHTILFSTQFMDEADILADRKVFL 689
Cdd:TIGR03269 422 DKYPDELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHsILKAREEmEQTFIIVSHDMDFVLDVCDRAALM 501
|
....*
gi 1387227070 690 SNGKL 694
Cdd:TIGR03269 502 RDGKI 506
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
1310-1496 |
2.54e-16 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 80.54 E-value: 2.54e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1310 NVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVfRDSGTpptrqagggfrHLGYCPQE---DVLWPdLTVRE 1386
Cdd:PRK09544 22 DVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIK-RNGKL-----------RIGYVPQKlylDTTLP-LTVNR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1387 HLDLYSAVKgltKEEAALSVSRLaDALKLQDQmalPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQ 1466
Cdd:PRK09544 89 FLRLRPGTK---KEDILPALKRV-QAGHLIDA---PMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALYD 161
|
170 180 190
....*....|....*....|....*....|
gi 1387227070 1467 AIQAIVKSSARGALLTTHSMAEAEAVCDRV 1496
Cdd:PRK09544 162 LIDQLRRELDCAVLMVSHDLHLVMAKTDEV 191
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
1309-1502 |
2.97e-16 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 83.95 E-value: 2.97e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1309 RNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVvfRDSGTPPTRQAGGGFRHLG-Y-CPQEDVLWPDLTVRE 1386
Cdd:PRK15439 28 KGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTL--EIGGNPCARLTPAKAHQLGiYlVPQEPLLFPNLSVKE 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1387 HLDLysavkGLTKEEAALsvSRLADALK-LQDQMALPAKA-LPEGAKRKLSFALSVLGSPA-LLLLDEPTTGMDPEGQLQ 1463
Cdd:PRK15439 106 NILF-----GLPKRQASM--QKMKQLLAaLGCQLDLDSSAgSLEVADRQIVEILRGLMRDSrILILDEPTASLTPAETER 178
|
170 180 190
....*....|....*....|....*....|....*....
gi 1387227070 1464 MWQAIQAIVKSSArGALLTTHSMAEAEAVCDRVAIMVSG 1502
Cdd:PRK15439 179 LFSRIRELLAQGV-GIVFISHKLPEIRQLADRISVMRDG 216
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
490-689 |
4.27e-16 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 78.43 E-value: 4.27e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 490 YKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATI-------YNTQLSEIINMeeirnytg 562
Cdd:NF040873 2 YGGRP----VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRaggarvaYVPQRSEVPDS-------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 563 fCPqfniyfdfLTVRE--NLRLFAKIK--GIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQV 638
Cdd:NF040873 70 -LP--------LTVRDlvAMGRWARRGlwRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADL 140
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 639 LLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEAdILADRKVFL 689
Cdd:NF040873 141 LLLDEPTTGLDAESRERIIALLAEeHARGATVVVVTHDLELV-RRADPCVLL 191
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
1307-1522 |
5.36e-16 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 79.29 E-value: 5.36e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVV-----VFrDSGTPPTRQAGGGFRH-LGYCPQEDVLWP 1380
Cdd:PRK11124 17 ALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLniagnHF-DFSKTPSDKAIRELRRnVGMVFQQYNLWP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 DLTVREHL-DLYSAVKGLTKEEAalsvsrLADALKLQDQMALPAKA------LPEGAKRKLSFALSVLGSPALLLLDEPT 1453
Cdd:PRK11124 96 HLTVQQNLiEAPCRVLGLSKDQA------LARAEKLLERLRLKPYAdrfplhLSGGQQQRVAIARALMMEPQVLLFDEPT 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1454 TGMDPEGQLQMWQAI---------QAIVkssargalltTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLK----SKFgKD 1520
Cdd:PRK11124 170 AALDPEITAQIVSIIrelaetgitQVIV----------THEVEVARKTASRVVYMENGHIVEQGDASCFTqpqtEAF-KN 238
|
..
gi 1387227070 1521 YL 1522
Cdd:PRK11124 239 YL 240
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
1305-1504 |
5.47e-16 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 78.76 E-value: 5.47e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF--------RDSGTPPTRqagggfRHLGYCPQED 1376
Cdd:PRK10908 15 RQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFsghditrlKNREVPFLR------RQIGMIFQDH 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1377 VLWPDLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGM 1456
Cdd:PRK10908 89 HLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLADEPTGNL 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 1457 D---PEGQLQMWQAIQAIvkssARGALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:PRK10908 169 DdalSEGILRLFEEFNRV----GVTVLMATHDIGLISRRSYRMLTLSDGHL 215
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
1306-1522 |
5.51e-16 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 84.02 E-value: 5.51e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1306 TAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAG-VVVF---------RDSGTPptRQAgggfrhlgYCPQE 1375
Cdd:NF033858 15 VALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGrVEVLggdmadarhRRAVCP--RIA--------YMPQG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1376 --DVLWPDLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPT 1453
Cdd:NF033858 85 lgKNLYPTLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDLLILDEPT 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 1454 TGMDPEGQLQMWQAIQAIvkSSARGA---LLTTHSMAEAEAvCDRVAIMVSGRLRCIGSVQHLKSKFGKDYL 1522
Cdd:NF033858 165 TGVDPLSRRQFWELIDRI--RAERPGmsvLVATAYMEEAER-FDWLVAMDAGRVLATGTPAELLARTGADTL 233
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
1307-1544 |
6.29e-16 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 82.65 E-value: 6.29e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRdsGTP----PTR---QAGGGFRHlgycpQEDVLW 1379
Cdd:PRK11288 19 ALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILID--GQEmrfaSTTaalAAGVAIIY-----QELHLV 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1380 PDLTVREHLDL------YSAV-KGLTKEEAALSVSRLADAL----KL------QDQMALPAKALPEGAKrklsfalsvlg 1442
Cdd:PRK11288 92 PEMTVAENLYLgqlphkGGIVnRRLLNYEAREQLEHLGVDIdpdtPLkylsigQRQMVEIAKALARNAR----------- 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1443 spaLLLLDEPTTGMDPEGQLQMWQAIQAIvKSSARGALLTTHSMAEAEAVCDRVAIMVSGRL------------------ 1504
Cdd:PRK11288 161 ---VIAFDEPTSSLSAREIEQLFRVIREL-RAEGRVILYVSHRMEEIFALCDAITVFKDGRYvatfddmaqvdrdqlvqa 236
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 1387227070 1505 ---RCIGSVQHLKSKFGKDYLLEVK-VKALTLVEPLHM-----EILKLF 1544
Cdd:PRK11288 237 mvgREIGDIYGYRPRPLGEVRLRLDgLKGPGLREPISFsvragEIVGLF 285
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
480-699 |
8.90e-16 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 82.57 E-value: 8.90e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGKPEKVeaLQGICLDVYEGQLTAILGHSGAGKSSLLSILG-GWSaCTEGSATIYNTQLSEiINMEEIR 558
Cdd:PRK11160 338 SLTLNNVSFTYPDQPQPV--LKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTrAWD-PQQGEILLNGQPIAD-YSEAALR 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 559 NYTGFCPQ----FNIyfdflTVRENLRLfAKikgipPKEVEQEVKSIMMELDMHNIQDVIA----------KELSGGQKR 624
Cdd:PRK11160 414 QAISVVSQrvhlFSA-----TLRDNLLL-AA-----PNASDEALIEVLQQVGLEKLLEDDKglnawlgeggRQLSGGEQR 482
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 625 KLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTILFST-------QFmdeadilaDRKVFLSNGKLRCA 697
Cdd:PRK11160 483 RLGIARALLHDAPLLLLDEPTEGLDAETERQILELLAEHAQNKTVLMIThrltgleQF--------DRICVMDNGQIIEQ 554
|
..
gi 1387227070 698 GS 699
Cdd:PRK11160 555 GT 556
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
1287-1504 |
9.76e-16 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 80.51 E-value: 9.76e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1287 LHKEYKQekkrcfsARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTRQAGGGF 1366
Cdd:COG1135 7 LSKTFPT-------KGGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLV--DGVDLTALSEREL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1367 RHL----GYCPQEDVLWPDLTVREH--LDLYSAvkGLTKEEAALSVSRLADALKLQDQmalpAKALPE----GAK----- 1431
Cdd:COG1135 78 RAArrkiGMIFQHFNLLSSRTVAENvaLPLEIA--GVPKAEIRKRVAELLELVGLSDK----ADAYPSqlsgGQKqrvgi 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 1432 -RklsfALSvlGSPALLLLDEPTTGMDPEGQlqmwQAIQAIVKSSAR--GA--LLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:COG1135 152 aR----ALA--NNPKVLLCDEATSALDPETT----RSILDLLKDINRelGLtiVLITHEMDVVRRICDRVAVLENGRI 219
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
482-687 |
9.86e-16 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 77.91 E-value: 9.86e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 482 RIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSA---CTEGSATIYNTQLSEIiNMEEIR 558
Cdd:COG4136 3 SLENLTITLGGRP----LLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSpafSASGEVLLNGRRLTAL-PAEQRR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 559 nyTGFCPQFNIYFDFLTVRENLrLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQV 638
Cdd:COG4136 78 --IGILFQDDLLFPHLSVGENL-AFALPPTIGRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRA 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1387227070 639 LLLDEPTAGLDP-----FsRHLVWNFLKERKTNhTILFStqfMDEADILADRKV 687
Cdd:COG4136 155 LLLDEPFSKLDAalraqF-REFVFEQIRQRGIP-ALLVT---HDEEDAPAAGRV 203
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
481-712 |
9.86e-16 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 78.43 E-value: 9.86e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKgkPEKvEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRNY 560
Cdd:cd03253 1 IEFENVTFAYD--PGR-PVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREV-TLDSLRRA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDfLTVRENLRlFAKIkGIPPKEVEQEVKSIMmeldmhnIQDVIAK--------------ELSGGQKRKL 626
Cdd:cd03253 77 IGVVPQDTVLFN-DTIGYNIR-YGRP-DATDEEVIEAAKAAQ-------IHDKIMRfpdgydtivgerglKLSGGEKQRV 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 627 TFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTILF-----STqFMDeadilADRKVFLSNGKLRCAGSSL 701
Cdd:cd03253 147 AIARAILKNPPILLLDEATSALDTHTEREIQAALRDVSKGRTTIViahrlST-IVN-----ADKIIVLKDGRIVERGTHE 220
|
250
....*....|.
gi 1387227070 702 FLKRKWGIgYH 712
Cdd:cd03253 221 ELLAKGGL-YA 230
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
1282-1504 |
1.01e-15 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 79.36 E-value: 1.01e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1282 IMASCLHKEYKQEKKrcfSARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPPT-- 1359
Cdd:PRK13633 3 EMIKCKNVSYKYESN---EESTEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEen 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1360 -----RQAGGGFRH-----LGYCPQEDVLW-PdltvrEHLdlysavkGLTKEEAALSVSRLADALKLQDQMALPAKALPE 1428
Cdd:PRK13633 80 lwdirNKAGMVFQNpdnqiVATIVEEDVAFgP-----ENL-------GIPPEEIRERVDESLKKVGMYEYRRHAPHLLSG 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 1429 GAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAeAVCDRVAIMVSGRL 1504
Cdd:PRK13633 148 GQKQRVAIAGILAMRPECIIFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEEA-VEADRIIVMDSGKV 222
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
1302-1503 |
1.10e-15 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 77.30 E-value: 1.10e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1302 RKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGV---VVFrdSGTPPTRQAGGGFRHLGYCPQEDVL 1378
Cdd:cd03233 17 RSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNVSVegdIHY--NGIPYKEFAEKYPGEIIYVSEEDVH 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1379 WPDLTVREHLDLysavkgltkeeaalsvsrladALKLQ-DQMAlpaKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMD 1457
Cdd:cd03233 95 FPTLTVRETLDF---------------------ALRCKgNEFV---RGISGGERKRVSIAEALVSRASVLCWDNSTRGLD 150
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1387227070 1458 PEGQLQMWQAIQAIVKSSaRGALLTTHSMA--EAEAVCDRVAIMVSGR 1503
Cdd:cd03233 151 SSTALEILKCIRTMADVL-KTTTFVSLYQAsdEIYDLFDKVLVLYEGR 197
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
1299-1473 |
1.13e-15 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 78.04 E-value: 1.13e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1299 FSARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF--RDSGTPPTRQAgggFRHLGYCPQED 1376
Cdd:cd03254 10 FSYDEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIdgIDIRDISRKSL---RSMIGVVLQDT 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1377 VLWPDlTVREHLDLYSAVKGLTKEEAALSVSRLADALK-----LQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDE 1451
Cdd:cd03254 87 FLFSG-TIMENIRLGRPNATDEEVIEAAKEAGAHDFIMklpngYDTVLGENGGNLSQGERQLLAIARAMLRDPKILILDE 165
|
170 180
....*....|....*....|..
gi 1387227070 1452 PTTGMDPEGQLQMWQAIQAIVK 1473
Cdd:cd03254 166 ATSNIDTETEKLIQEALEKLMK 187
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
481-702 |
1.28e-15 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 78.98 E-value: 1.28e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKgKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRNY 560
Cdd:PRK13642 5 LEVENLVFKYE-KESDVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAE-NVWNLRRK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQF-NIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVL 639
Cdd:PRK13642 83 IGMVFQNpDNQFVGATVEDDVAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEII 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 640 LLDEPTAGLDPFSRHLVWNFLKERKTNH--TILFSTQFMDEAdILADRKVFLSNGKL--RCAGSSLF 702
Cdd:PRK13642 163 ILDESTSMLDPTGRQEIMRVIHEIKEKYqlTVLSITHDLDEA-ASSDRILVMKAGEIikEAAPSELF 228
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
480-694 |
1.43e-15 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 81.61 E-value: 1.43e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGkpekVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGsaTIYntqlseiINMEE--I 557
Cdd:COG3845 5 ALELRGITKRFGG----VVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSG--EIL-------IDGKPvrI 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 558 RNytgfcPQ-------------FNIyFDFLTVRENLRLFAKIKG---IPPKEVEQEVKSIM----MELDMhniqDVIAKE 617
Cdd:COG3845 72 RS-----PRdaialgigmvhqhFML-VPNLTVAENIVLGLEPTKggrLDRKAARARIRELSerygLDVDP----DAKVED 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 618 LSGGQKRKLTfgI--AILGDPQVLLLDEPTAGLDPF-SRHLvWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGK 693
Cdd:COG3845 142 LSVGEQQRVE--IlkALYRGARILILDEPTAVLTPQeADEL-FEILRRlAAEGKSIIFITHKLREVMAIADRVTVLRRGK 218
|
.
gi 1387227070 694 L 694
Cdd:COG3845 219 V 219
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
1307-1485 |
1.55e-15 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 81.64 E-value: 1.55e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTRQAGGGFRHL-GYCPQEDVLWpDLTVR 1385
Cdd:TIGR02868 350 VLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTL--DGVPVSSLDQDEVRRRvSVCAQDAHLF-DTTVR 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1386 EHLDLysAVKGLTKEE--AALSVSRLADALK-----LQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDP 1458
Cdd:TIGR02868 427 ENLRL--ARPDATDEElwAALERVGLADWLRalpdgLDTVLGEGGARLSGGERQRLALARALLADAPILLLDEPTEHLDA 504
|
170 180
....*....|....*....|....*..
gi 1387227070 1459 EGQLQMWQAIQAIvkSSARGALLTTHS 1485
Cdd:TIGR02868 505 ETADELLEDLLAA--LSGRTVVLITHH 529
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
458-692 |
1.62e-15 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 82.85 E-value: 1.62e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 458 MNSELSCDDSFEPVSPEFHRKEairIRNLRKEYKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILggwsacT 537
Cdd:TIGR00956 740 DESDDVNDEKDMEKESGEDIFH---WRNLTYEVKIKKEKRVILNNVDGWVKPGTLTALMGASGAGKTTLLNVL------A 810
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 538 EGSATIYNTQLSEIINMEEI----RNYTGFCPQFNIYFDFLTVRENLRLFAKI---KGIPPKEVEQEVKSIMMELDMHNI 610
Cdd:TIGR00956 811 ERVTTGVITGGDRLVNGRPLdssfQRSIGYVQQQDLHLPTSTVRESLRFSAYLrqpKSVSKSEKMEYVEEVIKLLEMESY 890
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 611 QDVIAKE----LSGGQKRKLTFGIAILGDPQVLL-LDEPTAGLDPFSRHLVWNFLKE-RKTNHTILfSTQFMDEADILA- 683
Cdd:TIGR00956 891 ADAVVGVpgegLNVEQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKlADHGQAIL-CTIHQPSAILFEe 969
|
250
....*....|
gi 1387227070 684 -DRKVFLSNG 692
Cdd:TIGR00956 970 fDRLLLLQKG 979
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
513-699 |
2.49e-15 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 79.53 E-value: 2.49e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 513 TAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEI---INME-EIRNyTGFCPQFNIYFDFLTVRENLRLfakikG 588
Cdd:PRK11144 27 TAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDAekgICLPpEKRR-IGYVFQDARLFPHYKVRGNLRY-----G 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 589 IPPKEVEQeVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLD-PFSRHLVwNFLKE--RKT 665
Cdd:PRK11144 101 MAKSMVAQ-FDKIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDlPRKRELL-PYLERlaREI 178
|
170 180 190
....*....|....*....|....*....|....
gi 1387227070 666 NHTILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:PRK11144 179 NIPILYVSHSLDEILRLADRVVVLEQGKVKAFGP 212
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
1301-1484 |
3.12e-15 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 75.74 E-value: 3.12e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1301 ARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTkpTAGVVvfrdSG--TPPTRQAGGGF-RHLGYCPQEDV 1377
Cdd:cd03232 16 KGGKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGRK--TAGVI----TGeiLINGRPLDKNFqRSTGYVEQQDV 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1378 LWPDLTVREHLDLYSAVKGLTKEEaalsvsrladalklqdqmalpakalpegaKRKLSFALSVLGSPALLLLDEPTTGMD 1457
Cdd:cd03232 90 HSPNLTVREALRFSALLRGLSVEQ-----------------------------RKRLTIGVELAAKPSILFLDEPTSGLD 140
|
170 180
....*....|....*....|....*..
gi 1387227070 1458 PEGQLQMWQAIQAIVkSSARGALLTTH 1484
Cdd:cd03232 141 SQAAYNIVRFLKKLA-DSGQAILCTIH 166
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
481-699 |
3.13e-15 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 78.13 E-value: 3.13e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGK-PEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWsACTEGSATIYN-----TQLSEIINM 554
Cdd:PRK13645 7 IILDNVSYTYAKKtPFEFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGL-IISETGQTIVGdyaipANLKKIKEV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 555 EEIRNYTGFCPQFNIYFDFLTVRENLRLFAKIK-GIPPKEVEQEVKSImmeLDMHNIQDVIAK----ELSGGQKRKLTFG 629
Cdd:PRK13645 86 KRLRKEIGLVFQFPEYQLFQETIEKDIAFGPVNlGENKQEAYKKVPEL---LKLVQLPEDYVKrspfELSGGQKRRVALA 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 630 IAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHT--ILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:PRK13645 163 GIIAMDGNTLVLDEPTGGLDPKGEEDFINLFERLNKEYKkrIIMVTHNMDQVLRIADEVIVMHEGKVISIGS 234
|
|
| ABC2_membrane_3 |
pfam12698 |
ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter ... |
180-408 |
3.15e-15 |
|
ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter family pfam01061.
Pssm-ID: 463674 [Multi-domain] Cd Length: 345 Bit Score: 78.97 E-value: 3.15e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 180 AFQTAINAAIIEVTTNHSVM--EELISVVGINMRTPPFISKGESINEWF--IFICIVYFSPFVYVASlNITKER-KKFKK 254
Cdd:pfam12698 115 LILNALQSLLQQLNASALVLllEALSTSAPIPVESTPLFNPQSGYAYYLvgLILMIIILIGAAIIAV-SIVEEKeSRIKE 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 255 LMTAMGLQQSAFWLSWALMYAGFVFVVSIFMTLVIklFQMVI-LTGFVVLVSLFTLYGLSLIALAFLLCVLIKRPILTGV 333
Cdd:pfam12698 194 RLLVSGVSPLQYWLGKILGDFLVGLLQLLIILLLL--FGIGIpFGNLGLLLLLFLLYGLAYIALGYLLGSLFKNSEDAQS 271
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 334 VGSLFT-VFWGCLGFTALYRQLPSSLGWALCLFSPFAFTAGVAQISHQEYHVsgvvfpdPSGESYTMIVIFFLLAF 408
Cdd:pfam12698 272 IIGIVIlLLSGFFGGLFPLEDPPSFLQWIFSIIPFFSPIDGLLRLIYGDSLW-------EIAPSLIILLLFAVVLL 340
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
481-698 |
3.67e-15 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 80.60 E-value: 3.67e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGkpekVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINMEEIRNY 560
Cdd:PRK09700 6 ISMAGIGKSFGP----VHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKLAAQLG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFLTVRENL---RLFA-KIKGIPP---KEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAIL 633
Cdd:PRK09700 82 IGIIYQELSVIDELTVLENLyigRHLTkKVCGVNIidwREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLM 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 634 GDPQVLLLDEPTAGL-DPFSRHLVWNFLKERKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAG 698
Cdd:PRK09700 162 LDAKVIIMDEPTSSLtNKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSG 227
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
500-700 |
4.73e-15 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 77.01 E-value: 4.73e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 500 LQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQL---SEIINMEEI--RNYTGFCPQFNIYFDFL 574
Cdd:PRK14246 26 LKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLyfgKDIFQIDAIklRKEVGMVFQQPNPFPHL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 575 TVRENLRLFAKIKGIPPKE-----VEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLD 649
Cdd:PRK14246 106 SIYDNIAYPLKSHGIKEKReikkiVEECLRKVGLWKEVYDRLNSPASQLSGGQQQRLTIARALALKPKVLLMDEPTSMID 185
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 650 PFSRHLVWNFLKERKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGSS 700
Cdd:PRK14246 186 IVNSQAIEKLITELKNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSS 236
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
505-694 |
5.00e-15 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 76.16 E-value: 5.00e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 505 LDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIyNTQlseiinmeeirNYTGFCP---------QFNIYFDFLT 575
Cdd:PRK10771 20 LTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTL-NGQ-----------DHTTTPPsrrpvsmlfQENNLFSHLT 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 576 VRENLRLfakikGIPP-----KEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDP 650
Cdd:PRK10771 88 VAQNIGL-----GLNPglklnAAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDP 162
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1387227070 651 FSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:PRK10771 163 ALRQEMLTLVSQvcQERQLTLLMVSHSLEDAARIAPRSLVVADGRI 208
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
481-712 |
5.03e-15 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 78.92 E-value: 5.03e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGkpekVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINMEeiRNy 560
Cdd:PRK11000 4 VTLRNVTKAYGD----VVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPAE--RG- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLL 640
Cdd:PRK11000 77 VGMVFQSYALYPHLSVAENMSFGLKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFL 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 641 LDEPTAGLDPFSR----------HlvwnflkeRKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGSSLFLkrkwgig 710
Cdd:PRK11000 157 LDEPLSNLDAALRvqmrieisrlH--------KRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLEL------- 221
|
..
gi 1387227070 711 YH 712
Cdd:PRK11000 222 YH 223
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
481-717 |
5.76e-15 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 80.15 E-value: 5.76e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKpeKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRNY 560
Cdd:TIGR02203 331 VEFRNVTFRYPGR--DRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADY-TLASLRRQ 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFlTVRENLRlFAKIKGIPPKEVEQEvksimmeLDMHNIQDVIAK--------------ELSGGQKRKL 626
Cdd:TIGR02203 408 VALVSQDVVLFND-TIANNIA-YGRTEQADRAEIERA-------LAAAYAQDFVDKlplgldtpigengvLLSGGQRQRL 478
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 627 TFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTQFMDEADiLADRKVFLSNGKLRCAGS-SLFLKR 705
Cdd:TIGR02203 479 AIARALLKDAPILILDEATSALDNESERLVQAALERLMQGRTTLVIAHRLSTIE-KADRIVVMDDGRIVERGThNELLAR 557
|
250
....*....|..
gi 1387227070 706 KwgiGYHLSLHR 717
Cdd:TIGR02203 558 N---GLYAQLHN 566
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
1306-1508 |
7.03e-15 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 78.73 E-value: 7.03e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1306 TAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF--RDSGTPPTRQAGggfRHLGYCPQEDVLWPDLT 1383
Cdd:PRK09536 17 TVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVagDDVEALSARAAS---RRVASVPQDTSLSFEFD 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1384 VRE--------HLDLYSAVkGLTKEEAALSVSRLADALKLQDQmalPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTG 1455
Cdd:PRK09536 94 VRQvvemgrtpHRSRFDTW-TETDRAAVERAMERTGVAQFADR---PVTSLSGGERQRVLLARALAQATPVLLLDEPTAS 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 1456 MDPEGQLQMWQAIQAIVKsSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIG 1508
Cdd:PRK09536 170 LDINHQVRTLELVRRLVD-DGKTAVAAIHDLDLAARYCDELVLLADGRVRAAG 221
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
481-693 |
7.98e-15 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 73.25 E-value: 7.98e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGwsactegsatiyntqlseiinmeEIRNY 560
Cdd:cd03221 1 IELENLSKTYGGKL----LLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAG-----------------------ELEPD 53
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFcpqfniyfdfltvrenlrlFAKIKGIPPKEVEQevksimmeldmhniqdviakeLSGGQKRKLTFGIAILGDPQVLL 640
Cdd:cd03221 54 EGI-------------------VTWGSTVKIGYFEQ---------------------LSGGEKMRLALAKLLLENPNLLL 93
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 641 LDEPTAGLDPFSRHLVWNFLKErkTNHTILFST---QFMDEadiLADRKVFLSNGK 693
Cdd:cd03221 94 LDEPTNHLDLESIEALEEALKE--YPGTVILVShdrYFLDQ---VATKIIELEDGK 144
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
1278-1504 |
8.72e-15 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 75.62 E-value: 8.72e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1278 DEPVIMASCLHKEYkQEKKrcfsarkTKTAV-RNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGT 1356
Cdd:PRK11629 2 NKILLQCDNLCKRY-QEGS-------VQTDVlHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIF--NGQ 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1357 PPTRQAGGGF-----RHLGYCPQEDVLWPDLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAK 1431
Cdd:PRK11629 72 PMSKLSSAAKaelrnQKLGFIYQFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGER 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 1432 RKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVcDRVAIMVSGRL 1504
Cdd:PRK11629 152 QRVAIARALVNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRM-SRQLEMRDGRL 223
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
500-699 |
9.57e-15 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 77.83 E-value: 9.57e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 500 LQGICLDV----YEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATI-----YNTQLSeiINME-EIRNyTGFCPQFNI 569
Cdd:COG4148 11 RGGFTLDVdftlPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLggevlQDSARG--IFLPpHRRR-IGYVFQEAR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 570 YFDFLTVRENLRlFAkIKGIPPKEVEQEVKSImmeLDMHNIQDVIAK---ELSGGQKRKLTFGIAILGDPQVLLLDEPTA 646
Cdd:COG4148 88 LFPHLSVRGNLL-YG-RKRAPRAERRISFDEV---VELLGIGHLLDRrpaTLSGGERQRVAIGRALLSSPRLLLMDEPLA 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 647 GLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:COG4148 163 ALDLARKAEILPYLERlrDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGP 217
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
505-699 |
1.02e-14 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 78.15 E-value: 1.02e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 505 LDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINME--EIR-NYTGFCPQFNIYFDFLTVRENLR 581
Cdd:PRK10070 49 LAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAElrEVRrKKIAMVFQSFALMPHMTVLDNTA 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 582 LFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLK 661
Cdd:PRK10070 129 FGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDELV 208
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1387227070 662 ERKTNH--TILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:PRK10070 209 KLQAKHqrTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGT 248
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
481-694 |
1.03e-14 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 73.79 E-value: 1.03e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEKVeaLQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiINMEEIRNY 560
Cdd:cd03246 1 LEVENVSFRYPGAEPPV--LRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQ-WDPNELGDH 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFlTVRENLrlfakikgippkeveqevksimmeldmhniqdviakeLSGGQKRKLTFGIAILGDPQVLL 640
Cdd:cd03246 78 VGYLPQDDELFSG-SIAENI-------------------------------------LSGGQRQRLGLARALYGNPRILV 119
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 641 LDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMdEADILADRKVFLSNGKL 694
Cdd:cd03246 120 LDEPNSHLDVEGERALNQAIAAlKAAGATRIVIAHRP-ETLASADRILVLEDGRV 173
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
481-695 |
1.11e-14 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 75.20 E-value: 1.11e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIinMEEIR-- 558
Cdd:PRK10584 7 VEVHHLKKSVGQGEHELSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQM--DEEARak 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 559 ---NYTGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGD 635
Cdd:PRK10584 85 lraKHVGFVFQSFMLIPTLNALENVELPALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGR 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1387227070 636 PQVLLLDEPTAGLDpfsrhlvwnflkeRKTNHTI---LFS-------TQFMDEADI-LA---DRKVFLSNGKLR 695
Cdd:PRK10584 165 PDVLFADEPTGNLD-------------RQTGDKIadlLFSlnrehgtTLILVTHDLqLAarcDRRLRLVNGQLQ 225
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
1281-1513 |
1.34e-14 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 79.13 E-value: 1.34e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1281 VIMASCLHKEYKQEkkrcfsaRKTKTAVRNVSFCINKGEVLGLLGHNGAGKS-----------------TCIKMITgdTK 1343
Cdd:PRK10261 12 VLAVENLNIAFMQE-------QQKIAAVRNLSFSLQRGETLAIVGESGSGKSvtalalmrlleqagglvQCDKMLL--RR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1344 PTAGVVVFRDSGTPPTRQAGGGfrHLGYCPQEDV--LWPDLTVREHL-DLYSAVKGLTKEEAALSVSRLADALKLQDQMA 1420
Cdd:PRK10261 83 RSRQVIELSEQSAAQMRHVRGA--DMAMIFQEPMtsLNPVFTVGEQIaESIRLHQGASREEAMVEAKRMLDQVRIPEAQT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1421 LPAK---ALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVA 1497
Cdd:PRK10261 161 ILSRyphQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVL 240
|
250
....*....|....*.
gi 1387227070 1498 IMVSGRLRCIGSVQHL 1513
Cdd:PRK10261 241 VMYQGEAVETGSVEQI 256
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
1307-1523 |
1.43e-14 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 75.22 E-value: 1.43e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrDSGTPPTRQAGGGFRHLGYCPQEDVLWpDLTVRE 1386
Cdd:cd03252 17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLV-DGHDLALADPAWLRRQVGVVLQENVLF-NRSIRD 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1387 HLDLysAVKGLTKEEaALSVSRLADALKLQDQMAL--------PAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDP 1458
Cdd:cd03252 95 NIAL--ADPGMSMER-VIEAAKLAGAHDFISELPEgydtivgeQGAGLSGGQRQRIAIARALIHNPRILIFDEATSALDY 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 1459 EGQLQMWQAIQAIvkSSARGALLTTHSMAEAEAVcDRVAIMVSGRLRCIGSVQHLKSKFGKDYLL 1523
Cdd:cd03252 172 ESEHAIMRNMHDI--CAGRTVIIIAHRLSTVKNA-DRIIVMEKGRIVEQGSHDELLAENGLYAYL 233
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
1307-1503 |
1.65e-14 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 74.78 E-value: 1.65e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTP------PTRQAGGGFRH-LGYCPQ----- 1374
Cdd:COG4778 26 VLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDGGWvdlaqaSPREILALRRRtIGYVSQflrvi 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1375 -----EDVlwpdltVREHLdlysAVKGLTKEEAalsvsrLADALKLQDQMALPAK--ALPE-----GAKRKLSFALSVLG 1442
Cdd:COG4778 106 prvsaLDV------VAEPL----LERGVDREEA------RARARELLARLNLPERlwDLPPatfsgGEQQRVNIARGFIA 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 1443 SPALLLLDEPTTGMDPEGQLqmwQAIQAIVKSSARG-ALLT-THSMAEAEAVCDRVAIMVSGR 1503
Cdd:COG4778 170 DPPLLLLDEPTASLDAANRA---VVVELIEEAKARGtAIIGiFHDEEVREAVADRVVDVTPFS 229
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
1315-1504 |
1.76e-14 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 74.07 E-value: 1.76e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1315 INKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFR--DSGT-PPTRqagggfRHLGYCPQEDVLWPDLTVREHLDLy 1391
Cdd:cd03298 21 FAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINgvDVTAaPPAD------RPVSMLFQENNLFAHLTVEQNVGL- 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1392 SAVKGLT-KEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQA 1470
Cdd:cd03298 94 GLSPGLKlTAEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLVLD 173
|
170 180 190
....*....|....*....|....*....|....
gi 1387227070 1471 IVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:cd03298 174 LHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRI 207
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
481-693 |
1.79e-14 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 74.04 E-value: 1.79e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEKVE-ALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTqlseiinmeeirn 559
Cdd:cd03250 1 ISVEDASFTWDSGEQETSfTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS------------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 yTGFCPQ----FNiyfdfLTVRENLrLFAKIkgIPPKEVEQEVKSIMMELDM----HNIQDVIAkE----LSGGQKRKLT 627
Cdd:cd03250 68 -IAYVSQepwiQN-----GTIRENI-LFGKP--FDEERYEKVIKACALEPDLeilpDGDLTEIG-EkginLSGGQKQRIS 137
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 628 FGIAILGDPQVLLLDEPTAGLDPF-SRHLVWN----FLKERKTnhTILF--STQFMDEadilADRKVFLSNGK 693
Cdd:cd03250 138 LARAVYSDADIYLLDDPLSAVDAHvGRHIFENcilgLLLNNKT--RILVthQLQLLPH----ADQIVVLDNGR 204
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
1295-1516 |
2.02e-14 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 75.41 E-value: 2.02e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1295 KKRCFSARK-TKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVV-----VFRDSGTPPTRqagggfRH 1368
Cdd:PRK13632 11 ENVSFSYPNsENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIkidgiTISKENLKEIR------KK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1369 LGYCPQEdvlwPD-----LTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFAlSVLG- 1442
Cdd:PRK13632 85 IGIIFQN----PDnqfigATVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIA-SVLAl 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 1443 SPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAeAVCDRVAIMVSGRLRCIGSVQH-LKSK 1516
Cdd:PRK13632 160 NPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEA-ILADKVIVFSEGKLIAQGKPKEiLNNK 233
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
478-695 |
2.61e-14 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 77.80 E-value: 2.61e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 478 KEAIRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATI-YNTQLseiinmee 556
Cdd:COG0488 313 KKVLELEGLSKSYGDKT----LLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKLgETVKI-------- 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 557 irnytGFCPQFNIYFDF-LTVRENLRLFAkikgipPKEVEQEVKSiMMEL-----DMhniQDVIAKELSGGQKRKLTFGI 630
Cdd:COG0488 381 -----GYFDQHQEELDPdKTVLDELRDGA------PGGTEQEVRG-YLGRflfsgDD---AFKPVGVLSGGEKARLALAK 445
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 631 AILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTnhTILFST---QFMDEadiLADRKVFLSNGKLR 695
Cdd:COG0488 446 LLLSPPNVLLLDEPTNHLDIETLEALEEALDDFPG--TVLLVShdrYFLDR---VATRILEFEDGGVR 508
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
1320-1509 |
3.23e-14 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 74.66 E-value: 3.23e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1320 VLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPPTRQAGGGFRH----LGYCPQEDVLWPDLTVrehlDLYSAVK 1395
Cdd:PRK13638 29 VTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDYSKRGLLALRQqvatVFQDPEQQIFYTDIDS----DIAFSLR 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1396 GLTKEEAALSvSRLADALKLQDQMAL---PAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIV 1472
Cdd:PRK13638 105 NLGVPEAEIT-RRVDEALTLVDAQHFrhqPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAGRTQMIAIIRRIV 183
|
170 180 190
....*....|....*....|....*....|....*..
gi 1387227070 1473 kSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGS 1509
Cdd:PRK13638 184 -AQGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGA 219
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
481-713 |
3.54e-14 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 74.06 E-value: 3.54e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKgkPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSeIINMEEIRNY 560
Cdd:cd03252 1 ITFEHVRFRYK--PDGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLA-LADPAWLRRQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDfLTVRENLRLFAKikGIPPKEVEQEVK-----SIMMELDMHniQDVIAKE----LSGGQKRKLTFGIA 631
Cdd:cd03252 78 VGVVLQENVLFN-RSIRDNIALADP--GMSMERVIEAAKlagahDFISELPEG--YDTIVGEqgagLSGGQRQRIAIARA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 632 ILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTQFMdEADILADRKVFLSNGKLRCAGSSLFLKRKWGIGY 711
Cdd:cd03252 153 LIHNPRILIFDEATSALDYESEHAIMRNMHDICAGRTVIIIAHRL-STVKNADRIIVMEKGRIVEQGSHDELLAENGLYA 231
|
..
gi 1387227070 712 HL 713
Cdd:cd03252 232 YL 233
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
1307-1504 |
3.82e-14 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 74.73 E-value: 3.82e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVV-------FRDSGTPPTRQAGG-GFRHlgycPQEDVL 1378
Cdd:PRK13639 17 ALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLikgepikYDKKSLLEVRKTVGiVFQN----PDDQLF 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1379 WPdlTVREHLDLYSAVKGLTKEEAAlsvSRLADALK---LQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTG 1455
Cdd:PRK13639 93 AP--TVEEDVAFGPLNLGLSKEEVE---KRVKEALKavgMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSG 167
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1387227070 1456 MDPEGQLQMWQAIQAIVKSSARgALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:PRK13639 168 LDPMGASQIMKLLYDLNKEGIT-IIISTHDVDLVPVYADKVYVMSDGKI 215
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
1312-1513 |
3.98e-14 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 73.64 E-value: 3.98e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1312 SFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPTRQagggfrhlgycP-----QEDVLWPDLT 1383
Cdd:COG3840 19 DLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGqdlTALPPAER-----------PvsmlfQENNLFPHLT 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1384 VREH--LDLYSAVKgLTKEEAAlsvsRLADALK---LQDQMA-LPAkALPEGAKRKLSFALSVLGSPALLLLDEPTTGMD 1457
Cdd:COG3840 88 VAQNigLGLRPGLK-LTAEQRA----QVEQALErvgLAGLLDrLPG-QLSGGQRQRVALARCLVRKRPILLLDEPFSALD 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 1458 PEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHL 1513
Cdd:COG3840 162 PALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAAL 217
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
1307-1504 |
4.31e-14 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 73.76 E-value: 4.31e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPPTRQAGGGFRHLGYCPQEDVLWPDLTVRE 1386
Cdd:PRK11614 20 ALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKIMREAVAIVPEGRRVFSRMTVEE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1387 HLdlysAVKGL--TKEEAALSVSRLADAL-KLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQ 1463
Cdd:PRK11614 100 NL----AMGGFfaERDQFQERIKWVYELFpRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLLLDEPSLGLAPIIIQQ 175
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1387227070 1464 MWQAIQAIvKSSARGALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:PRK11614 176 IFDTIEQL-REQGMTIFLVEQNANQALKLADRGYVLENGHV 215
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
498-650 |
5.76e-14 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 72.39 E-value: 5.76e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 498 EALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRN--YTGFCPQFNiyfDFLT 575
Cdd:TIGR01189 14 MLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQ-RDEPHENilYLGHLPGLK---PELS 89
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 576 VRENLRLFAKIKGIPPKEVEQEVKsimmELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDP 650
Cdd:TIGR01189 90 ALENLHFWAAIHGGAQRTIEDALA----AVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDK 160
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
499-690 |
5.76e-14 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 74.05 E-value: 5.76e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 499 ALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGW-----SACTEGSATIYNTQL-SEIINMEEIRNYTGFCPQFNIYFD 572
Cdd:PRK14243 25 AVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLndlipGFRVEGKVTFHGKNLyAPDVDPVEVRRRIGMVFQKPNPFP 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 573 fLTVRENLRLFAKI---KGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLD 649
Cdd:PRK14243 105 -KSIYDNIAYGARIngyKGDMDELVERSLRQAALWDEVKDKLKQSGLSLSGGQQQRLCIARAIAVQPEVILMDEPCSALD 183
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1387227070 650 PFSRHLVWNFLKERKTNHTILFSTQFMDEADILADRKVFLS 690
Cdd:PRK14243 184 PISTLRIEELMHELKEQYTIIIVTHNMQQAARVSDMTAFFN 224
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
1315-1496 |
5.82e-14 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 73.60 E-value: 5.82e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1315 INKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGvvvfrDSGTPPTRQAgggfrhlgYCPQEdvLWPDLTVREHLDLYSAV 1394
Cdd:cd03237 22 ISESEVIGILGPNGIGKTTFIKMLAGVLKPDEG-----DIEIELDTVS--------YKPQY--IKADYEGTVRDLLSSIT 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1395 KGLTkeEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSvLGSPA-LLLLDEPTTGMDPEGQLQMWQAIQAIVK 1473
Cdd:cd03237 87 KDFY--THPYFKTEIAKPLQIEQILDREVPELSGGELQRVAIAAC-LSKDAdIYLLDEPSAYLDVEQRLMASKVIRRFAE 163
|
170 180
....*....|....*....|...
gi 1387227070 1474 SSARGALLTTHSMAEAEAVCDRV 1496
Cdd:cd03237 164 NNEKTAFVVEHDIIMIDYLADRL 186
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
483-694 |
6.02e-14 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 73.56 E-value: 6.02e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 483 IRNLRKEYKGKpekvEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIinmeeirnytg 562
Cdd:PRK11247 15 LNAVSKRYGER----TVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLAEA----------- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 563 fcpqfniyfdfltvRENLRL-FAKIKGIPPKEVEQEV---------KSIMMELDMHNIQDViAKE----LSGGQKRKLTF 628
Cdd:PRK11247 80 --------------REDTRLmFQDARLLPWKKVIDNVglglkgqwrDAALQALAAVGLADR-ANEwpaaLSGGQKQRVAL 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 629 GIAILGDPQVLLLDEPTAGLDPFSR----HLV---WnflkeRKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:PRK11247 145 ARALIHRPGLLLLDEPLGALDALTRiemqDLIeslW-----QQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
481-761 |
6.20e-14 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 76.63 E-value: 6.20e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGkpekVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNtqlseiinmeeiRNY 560
Cdd:PRK15439 12 LCARSISKQYSG----VEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGG------------NPC 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCP----QFNIY--------FDFLTVRENLrLFakikGIP-PKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLT 627
Cdd:PRK15439 76 ARLTPakahQLGIYlvpqepllFPNLSVKENI-LF----GLPkRQASMQKMKQLLAALGCQLDLDSSAGSLEVADRQIVE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 628 FGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGSSlflkrk 706
Cdd:PRK15439 151 ILRGLMRDSRILILDEPTASLTPAETERLFSRIRElLAQGVGIVFISHKLPEIRQLADRISVMRDGTIALSGKT------ 224
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 707 wgigyhlslhrnERCNTERITSLITQHISDAKLTAenEEKLVYTLPLERTDKFPD 761
Cdd:PRK15439 225 ------------ADLSTDDIIQAITPAAREKSLSA--SQKLWLELPGNRRQQAAG 265
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
1304-1504 |
7.04e-14 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 71.69 E-value: 7.04e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1304 TKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF--RDSGTPPTRQAgggFRH-LGYCP---QEDV 1377
Cdd:cd03215 12 VKGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLdgKPVTRRSPRDA---IRAgIAYVPedrKREG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1378 LWPDLTVREHldlysavkgltkeeaaLSVSRLadalkL----QdQMALPAKALPEGAKrklsfalsvlgspaLLLLDEPT 1453
Cdd:cd03215 89 LVLDLSVAEN----------------IALSSL-----LsggnQ-QKVVLARWLARDPR--------------VLILDEPT 132
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1387227070 1454 TGMDPEGQlqmwQAI-QAIVKSSARGA--LLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:cd03215 133 RGVDVGAK----AEIyRLIRELADAGKavLLISSELDELLGLCDRILVMYEGRI 182
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
483-695 |
8.15e-14 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 76.26 E-value: 8.15e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 483 IRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIyntqlseiinmeeIRNYT- 561
Cdd:COG0488 1 LENLSKSFGGRP----LLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSI-------------PKGLRi 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 562 GFCPQFNIYFDFLTVRENL--------------------------------RLFAKIKGIPPKEVEQEVKSIMMEL---- 605
Cdd:COG0488 64 GYLPQEPPLDDDLTVLDTVldgdaelraleaeleeleaklaepdedlerlaELQEEFEALGGWEAEARAEEILSGLgfpe 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 606 DMHNiQDViaKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHlvW--NFLKERKtnHTILFST---QFMDEad 680
Cdd:COG0488 144 EDLD-RPV--SELSGGWRRRVALARALLSEPDLLLLDEPTNHLDLESIE--WleEFLKNYP--GTVLVVShdrYFLDR-- 214
|
250
....*....|....*
gi 1387227070 681 iLADRKVFLSNGKLR 695
Cdd:COG0488 215 -VATRILELDRGKLT 228
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
481-670 |
8.83e-14 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 72.06 E-value: 8.83e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKgkPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiINMEEIRNY 560
Cdd:cd03369 7 IEVENLSVRYA--PDLPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDIST-IPLEDLRSS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFlTVRENLRLFAkikgippkevEQEVKSIMMELDMhniqdviaKE----LSGGQKRKLTFGIAILGDP 636
Cdd:cd03369 84 LTIIPQDPTLFSG-TIRSNLDPFD----------EYSDEEIYGALRV--------SEgglnLSQGQRQLLCLARALLKRP 144
|
170 180 190
....*....|....*....|....*....|....
gi 1387227070 637 QVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTIL 670
Cdd:cd03369 145 RVLVLDEATASIDYATDALIQKTIREEFTNSTIL 178
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
498-718 |
9.50e-14 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 76.32 E-value: 9.50e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 498 EALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRNYTGFCPQFNIYFDFlTVR 577
Cdd:TIGR01193 488 NILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDI-DRHTLRQFINYLPQEPYIFSG-SIL 565
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 578 ENLRLFAKiKGIPPKEVEQEVKSIMMELDMHNIQ-------DVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDP 650
Cdd:TIGR01193 566 ENLLLGAK-ENVSQDEIWAACEIAEIKDDIENMPlgyqtelSEEGSSISGGQKQRIALARALLTDSKVLILDESTSNLDT 644
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 651 FSRH-LVWNFLKerKTNHTILFSTQFMDEADiLADRKVFLSNGKLRCAGSSL-FLKRKwgiGYHLSLHRN 718
Cdd:TIGR01193 645 ITEKkIVNNLLN--LQDKTIIFVAHRLSVAK-QSDKIIVLDHGKIIEQGSHDeLLDRN---GFYASLIHN 708
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
1313-1495 |
9.83e-14 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 72.19 E-value: 9.83e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1313 FCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVvfRDSGTPPTRqaGGGFRHLGYCPQEDVLWPDLTVREHLDLYS 1392
Cdd:PRK13543 32 FHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQI--QIDGKTATR--GDRSRFMAYLGHLPGLKADLSTLENLHFLC 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1393 AVKGLTKEE---AALSVSRLADalkLQDQMAlpaKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQ 1469
Cdd:PRK13543 108 GLHGRRAKQmpgSALAIVGLAG---YEDTLV---RQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDLEGITLVNRMIS 181
|
170 180
....*....|....*....|....*.
gi 1387227070 1470 AIVKSSArGALLTTHSMAEAEAVCDR 1495
Cdd:PRK13543 182 AHLRGGG-AALVTTHGAYAAPPVRTR 206
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
476-694 |
9.88e-14 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 72.50 E-value: 9.88e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 476 HRKEAIRIRNLRKEYKGKPEkVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINmE 555
Cdd:cd03248 7 HLKGIVKFQNVTFAYPTRPD-TLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEH-K 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 556 EIRNYTGFCPQFNIYFDfLTVRENLRLfakikGIPPKEVEqEVK---------SIMMELDMHNIQDVIAK--ELSGGQKR 624
Cdd:cd03248 85 YLHSKVSLVGQEPVLFA-RSLQDNIAY-----GLQSCSFE-CVKeaaqkahahSFISELASGYDTEVGEKgsQLSGGQKQ 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 625 KLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTQFMDEADiLADRKVFLSNGKL 694
Cdd:cd03248 158 RVAIARALIRNPQVLILDEATSALDAESEQQVQQALYDWPERRTVLVIAHRLSTVE-RADQILVLDGGRI 226
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
510-719 |
1.07e-13 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 76.04 E-value: 1.07e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 510 GQLTAILGHSGAGKSSLLSILGGWSACtEGSATIYNTQLSEIiNMEEIR---NYTGFCPQfniyfdfL---TVRENLRLf 583
Cdd:PRK11174 376 GQRIALVGPSGAGKTSLLNALLGFLPY-QGSLKINGIELREL-DPESWRkhlSWVGQNPQ-------LphgTLRDNVLL- 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 584 AKIKgIPPKEVEQE---------VKSIMMELDmHNIQDVIAKeLSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRH 654
Cdd:PRK11174 446 GNPD-ASDEQLQQAlenawvsefLPLLPQGLD-TPIGDQAAG-LSVGQAQRLALARALLQPCQLLLLDEPTASLDAHSEQ 522
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 655 LVWNFLKERKTNHTILFSTQFMDEadiLA--DRKVFLSNGKLRCAGSSLFLKRKWGIGYHLSLHRNE 719
Cdd:PRK11174 523 LVMQALNAASRRQTTLMVTHQLED---LAqwDQIWVMQDGQIVQQGDYAELSQAGGLFATLLAHRQE 586
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1306-1511 |
1.33e-13 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 75.59 E-value: 1.33e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1306 TAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPPTRQAGGGFRHLGYCPQEDVLWPDLTVR 1385
Cdd:PRK09700 19 HALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKLAAQLGIGIIYQELSVIDELTVL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1386 EHL----DLYSAVKGLT-------KEEAALSVSRLADALKLQDQMAlpakALPEGAKRKLSFALSVLGSPALLLLDEPTT 1454
Cdd:PRK09700 99 ENLyigrHLTKKVCGVNiidwremRVRAAMMLLRVGLKVDLDEKVA----NLSISHKQMLEIAKTLMLDAKVIIMDEPTS 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 1455 GMDPEGQLQMWqAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQ 1511
Cdd:PRK09700 175 SLTNKEVDYLF-LIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGMVS 230
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
1307-1538 |
1.35e-13 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 73.10 E-value: 1.35e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFR--DSGTPPTRQaggGFRHL-GYCPQE-DVLWPDL 1382
Cdd:PRK13644 17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSgiDTGDFSKLQ---GIRKLvGIVFQNpETQFVGR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1383 TVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQL 1462
Cdd:PRK13644 94 TVEEDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDSGI 173
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 1463 QMWQAIQAIvKSSARGALLTTHSMAEAEAVcDRVAIMVSGRLRCIGSVQHLKSKFGKDYLLEVKVKALTLVEPLHM 1538
Cdd:PRK13644 174 AVLERIKKL-HEKGKTIVYITHNLEELHDA-DRIIVMDRGKIVLEGEPENVLSDVSLQTLGLTPPSLIELAENLKM 247
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
1303-1504 |
1.38e-13 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 72.48 E-value: 1.38e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1303 KTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPTRQAGGGFR----HLGYCPQE 1375
Cdd:PRK11264 14 HGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDitiDTARSLSQQKGLIRqlrqHVGFVFQN 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1376 DVLWPDLTVREH-LDLYSAVKGLTKEEA-ALSVSRLADALKLQDQMALPaKALPEGAKRKLSFALSVLGSPALLLLDEPT 1453
Cdd:PRK11264 94 FNLFPHRTVLENiIEGPVIVKGEPKEEAtARARELLAKVGLAGKETSYP-RRLSGGQQQRVAIARALAMRPEVILFDEPT 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 1454 TGMDPEGQLQMWQAIQAIVKSSaRGALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:PRK11264 173 SALDPELVGEVLNTIRQLAQEK-RTMVIVTHEMSFARDVADRAIFMDQGRI 222
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
481-694 |
1.54e-13 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 72.05 E-value: 1.54e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKgkpeKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSilggwsaCTEGSATIYNTQL--------SEII 552
Cdd:PRK09493 2 IEFKNVSKHFG----PTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLR-------CINKLEEITSGDLivdglkvnDPKV 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 553 NMEEIRNYTGFC-PQFNIyFDFLTVRENLrLFA--KIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFG 629
Cdd:PRK09493 71 DERLIRQEAGMVfQQFYL-FPHLTALENV-MFGplRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIA 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 630 IAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:PRK09493 149 RALAVKPKLMLFDEPTSALDPELRHEVLKVMQDlAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRI 214
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
1298-1523 |
1.62e-13 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 71.88 E-value: 1.62e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1298 CFSARKTKTAV-RNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF-----RDSGTPPTRqagggfRHLGY 1371
Cdd:cd03251 7 TFRYPGDGPPVlRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIdghdvRDYTLASLR------RQIGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1372 CPQEDVLWPDlTVREHLdLYsAVKGLTKEEaALSVSRLADALKLQDQMalpakalPE---------------GAKRKLSF 1436
Cdd:cd03251 81 VSQDVFLFND-TVAENI-AY-GRPGATREE-VEEAARAANAHEFIMEL-------PEgydtvigergvklsgGQRQRIAI 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1437 ALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSsaRGALLTTHSMAEAEAVcDRVAIMVSGRLRCIGSVQHLKSK 1516
Cdd:cd03251 150 ARALLKDPPILILDEATSALDTESERLVQAALERLMKN--RTTFVIAHRLSTIENA-DRIVVLEDGKIVERGTHEELLAQ 226
|
....*..
gi 1387227070 1517 FGKDYLL 1523
Cdd:cd03251 227 GGVYAKL 233
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
1305-1517 |
1.79e-13 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 75.22 E-value: 1.79e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITG--DTKPTAGVVVFRDSGTP-------------PTRQAGGGFRhl 1369
Cdd:TIGR03269 13 KEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGmdQYEPTSGRIIYHVALCEkcgyverpskvgePCPVCGGTLE-- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1370 gycPQEDVLW-PDLTVREHLDLYSAVK------------------------GLTKEEAALSVSRLADALKLQDQMALPAK 1424
Cdd:TIGR03269 91 ---PEEVDFWnLSDKLRRRIRKRIAIMlqrtfalygddtvldnvlealeeiGYEGKEAVGRAVDLIEMVQLSHRITHIAR 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1425 ALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:TIGR03269 168 DLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIEDLSDKAIWLENGEI 247
|
250
....*....|...
gi 1387227070 1505 RCIGSVQHLKSKF 1517
Cdd:TIGR03269 248 KEEGTPDEVVAVF 260
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
1291-1509 |
1.87e-13 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 72.84 E-value: 1.87e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1291 YKQEKKRCFSARktktAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPTRQAGGGFR 1367
Cdd:PRK13643 9 YTYQPNSPFASR----ALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDivvSSTSKQKEIKPVRK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1368 HLGYCPQ--EDVLWPDlTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAK-ALPEGAKRKLSFALSVLGSP 1444
Cdd:PRK13643 85 KVGVVFQfpESQLFEE-TVLKDVAFGPQNFGIPKEKAEKIAAEKLEMVGLADEFWEKSPfELSGGQMRRVAIAGILAMEP 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 1445 ALLLLDEPTTGMDPEGQLQMWQAIQAIvKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGS 1509
Cdd:PRK13643 164 EVLVLDEPTAGLDPKARIEMMQLFESI-HQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGT 227
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
1291-1509 |
2.09e-13 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 72.73 E-value: 2.09e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1291 YKQEKKRCFSARktktAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPPT----------- 1359
Cdd:PRK13645 14 YTYAKKTPFEFK----ALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAIPANlkkikevkrlr 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1360 RQAGGGFRHLGYCPQEDVLWPDLTVRE-HLdlysavkGLTKEEAALSVSRLADALKLQDQMALPAK-ALPEGAKRKLSFA 1437
Cdd:PRK13645 90 KEIGLVFQFPEYQLFQETIEKDIAFGPvNL-------GENKQEAYKKVPELLKLVQLPEDYVKRSPfELSGGQKRRVALA 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 1438 LSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGS 1509
Cdd:PRK13645 163 GIIAMDGNTLVLDEPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGS 234
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
1305-1504 |
2.23e-13 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 72.02 E-value: 2.23e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVfrdSGTPPTRQAGGGFRHLGycpQEDVLWPDLTV 1384
Cdd:PRK11247 25 RTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELL---AGTAPLAEAREDTRLMF---QDARLLPWKKV 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1385 REHLDLysAVKGLTKEEA--ALSVSRLADalKLQDqmaLPAkALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQL 1462
Cdd:PRK11247 99 IDNVGL--GLKGQWRDAAlqALAAVGLAD--RANE---WPA-ALSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRI 170
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1387227070 1463 QMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:PRK11247 171 EMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
1277-1504 |
2.32e-13 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 71.92 E-value: 2.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1277 LDEPVIMASCLHKEYKQEKkrcfsarktktAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGT 1356
Cdd:PRK10619 1 MSENKLNVIDLHKRYGEHE-----------VLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTI 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1357 PPTRQAGGGFR------------HLGYCPQEDVLWPDLTVREH-LDLYSAVKGLTKEEAALSVSRLADALKLQD--QMAL 1421
Cdd:PRK10619 70 NLVRDKDGQLKvadknqlrllrtRLTMVFQHFNLWSHMTVLENvMEAPIQVLGLSKQEARERAVKYLAKVGIDEraQGKY 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1422 PAKaLPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKsSARGALLTTHSMAEAEAVCDRVAIMVS 1501
Cdd:PRK10619 150 PVH-LSGGQQQRVSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAE-EGKTMVVVTHEMGFARHVSSHVIFLHQ 227
|
...
gi 1387227070 1502 GRL 1504
Cdd:PRK10619 228 GKI 230
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
481-700 |
2.48e-13 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 71.97 E-value: 2.48e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYkgkpEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSAT----IYNTQLSEIINMEE 556
Cdd:PRK09984 5 IRVEKLAKTF----NQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKSAGShielLGRTVQREGRLARD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 557 IRN---YTGFC-PQFNIyFDFLTVRENLrLFAKIKGIP---------PKEVEQEVKSIMMELDMHNIQDVIAKELSGGQK 623
Cdd:PRK09984 81 IRKsraNTGYIfQQFNL-VNRLSVLENV-LIGALGSTPfwrtcfswfTREQKQRALQALTRVGMVHFAHQRVSTLSGGQQ 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 624 RKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNH--TILFSTQFMDEADILADRKVFLSNGKLRCAGSS 700
Cdd:PRK09984 159 QRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDgiTVVVTLHQVDYALRYCERIVALRQGHVFYDGSS 237
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
477-699 |
2.84e-13 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 71.76 E-value: 2.84e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 477 RKEAIRIRNLRKEYkgkpEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNtqlsEIINM-- 554
Cdd:COG4598 5 APPALEVRDLHKSF----GDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGG----EEIRLkp 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 555 --------------EEIRNYTGFCPQ-FNIYfDFLTVRENLrLFAKI--KGIPPKEVEQEVKSIMMELDMHNIQDVIAKE 617
Cdd:COG4598 77 drdgelvpadrrqlQRIRTRLGMVFQsFNLW-SHMTVLENV-IEAPVhvLGRPKAEAIERAEALLAKVGLADKRDAYPAH 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 618 LSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPfsrHLVWNFLK-------ERKtnhTILFSTQFMDEADILADRKVFLS 690
Cdd:COG4598 155 LSGGQQQRAAIARALAMEPEVMLFDEPTSALDP---ELVGEVLKvmrdlaeEGR---TMLVVTHEMGFARDVSSHVVFLH 228
|
....*....
gi 1387227070 691 NGKLRCAGS 699
Cdd:COG4598 229 QGRIEEQGP 237
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
1307-1524 |
3.60e-13 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 74.16 E-value: 3.60e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPPTRQAGggfrhlgycpqedvLWPDLTVRE 1386
Cdd:PRK13545 39 ALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGSAALIAISSG--------------LNGQLTGIE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1387 HLDLYSAVKGLTKE---EAALSVSRLADALKLQDQmalPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQ 1463
Cdd:PRK13545 105 NIELKGLMMGLTKEkikEIIPEIIEFADIGKFIYQ---PVKTYSSGMKSRLGFAISVHINPDILVIDEALSVGDQTFTKK 181
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 1464 MWQAIQAIvKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLKSKFGkDYLLE 1524
Cdd:PRK13545 182 CLDKMNEF-KEQGKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVVDHYD-EFLKK 240
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
1303-1504 |
3.63e-13 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 69.26 E-value: 3.63e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1303 KTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSgtpPTRQAGGGFRHL-GYCPQEDVLWpD 1381
Cdd:cd03247 13 QEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGV---PVSDLEKALSSLiSVLNQRPYLF-D 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 LTVREHLdlysavkgltkeeaalsvsrladalklqdqmalpAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQ 1461
Cdd:cd03247 89 TTLRNNL----------------------------------GRRFSGGERQRLALARILLQDAPIVLLDEPTVGLDPITE 134
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1387227070 1462 LQMWQAIQAIVKSsaRGALLTTHSMAEAEAVcDRVAIMVSGRL 1504
Cdd:cd03247 135 RQLLSLIFEVLKD--KTLIWITHHLTGIEHM-DKILFLENGKI 174
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
1305-1504 |
5.80e-13 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 71.40 E-value: 5.80e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD-SGTPPT---------RQAGGGFRHlgycpQ 1374
Cdd:PRK13641 20 KKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGyHITPETgnknlkklrKKVSLVFQF-----P 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1375 EDVLWPDlTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAK-ALPEGAKRKLSFALSVLGSPALLLLDEPT 1453
Cdd:PRK13641 95 EAQLFEN-TVLKDVEFGPKNFGFSEDEAKEKALKWLKKVGLSEDLISKSPfELSGGQMRRVAIAGVMAYEPEILCLDEPA 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 1454 TGMDPEGQLQMWQAIQAIVKsSARGALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:PRK13641 174 AGLDPEGRKEMMQLFKDYQK-AGHTVILVTHNMDDVAEYADDVLVLEHGKL 223
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
1311-1504 |
5.83e-13 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 71.28 E-value: 5.83e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1311 VSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrDSGTPPTRQAGGGFRHLGYCPQE-DVLWPDLTVREHLD 1389
Cdd:PRK13642 26 VSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKI-DGELLTAENVWNLRRKIGMVFQNpDNQFVGATVEDDVA 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1390 LYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQ 1469
Cdd:PRK13642 105 FGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIH 184
|
170 180 190
....*....|....*....|....*....|....*
gi 1387227070 1470 AIVKSSARGALLTTHSMAEAeAVCDRVAIMVSGRL 1504
Cdd:PRK13642 185 EIKEKYQLTVLSITHDLDEA-ASSDRILVMKAGEI 218
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
1308-1513 |
6.08e-13 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 70.50 E-value: 6.08e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1308 VRNVSFCINKGEVLGLLGHNGAGKS-TC---IKMITGDTKPTAGVVVFrdSGTPPTRQAGGGfRHLGYCPQ--EDVLWPD 1381
Cdd:PRK10418 19 VHGVSLTLQRGRVLALVGGSGSGKSlTCaaaLGILPAGVRQTAGRVLL--DGKPVAPCALRG-RKIATIMQnpRSAFNPL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 LTVREHLDLYSAVKGLTKEEAALSvsRLADALKLQDQMALP---AKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDP 1458
Cdd:PRK10418 96 HTMHTHARETCLALGKPADDATLT--AALEAVGLENAARVLklyPFEMSGGMLQRMMIALALLCEAPFIIADEPTTDLDV 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 1459 EGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHL 1513
Cdd:PRK10418 174 VAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETL 228
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
482-694 |
6.76e-13 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 73.02 E-value: 6.76e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 482 RIRNLRKEYKGkpekVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIyntqlseiinMEEIRNYT 561
Cdd:PRK11288 6 SFDGIGKTFPG----VKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILI----------DGQEMRFA 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 562 GFCPQFN-----IYFDF-----LTVRENL---RLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTF 628
Cdd:PRK11288 72 STTAALAagvaiIYQELhlvpeMTVAENLylgQLPHKGGIVNRRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEI 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 629 GIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:PRK11288 152 AKALARNARVIAFDEPTSSLSAREIEQLFRVIRElRAEGRVILYVSHRMEEIFALCDAITVFKDGRY 218
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
1308-1484 |
6.90e-13 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 69.21 E-value: 6.90e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1308 VRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPPTRQAGGgfRHLGYCPQEDVLWPDLTVREH 1387
Cdd:PRK13540 17 LQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKKDLCTYQ--KQLCFVGHRSGINPYLTLREN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1388 --LDLYSAvkgltkeEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMW 1465
Cdd:PRK13540 95 clYDIHFS-------PGAVGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLTII 167
|
170
....*....|....*....
gi 1387227070 1466 QAIQAIVKSSArGALLTTH 1484
Cdd:PRK13540 168 TKIQEHRAKGG-AVLLTSH 185
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
510-649 |
7.42e-13 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 74.11 E-value: 7.42e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 510 GQLTAILGHSGAGKSSLLSILGG--WSACTEGSATIYNTQLseiiNMEEIRNYTGFCPQFNIYFDFLTVRENLRLFAKIK 587
Cdd:PLN03140 906 GVLTALMGVSGAGKTTLMDVLAGrkTGGYIEGDIRISGFPK----KQETFARISGYCEQNDIHSPQVTVRESLIYSAFLR 981
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 588 giPPKEVEQEVKSI----MMEL-DMHNIQDVIA-----KELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLD 649
Cdd:PLN03140 982 --LPKEVSKEEKMMfvdeVMELvELDNLKDAIVglpgvTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLD 1051
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
1299-1509 |
7.66e-13 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 73.28 E-value: 7.66e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1299 FSARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrDsGTPPT-------RqagggfRHLGY 1371
Cdd:COG1132 347 FSYPGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILI-D-GVDIRdltleslR------RQIGV 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1372 CPQEDVLWpDLTVREHLDLysAVKGLTKEE--AALsvsRLADALKLqdqmalpAKALPEG-----AKR----------KL 1434
Cdd:COG1132 419 VPQDTFLF-SGTIRENIRY--GRPDATDEEveEAA---KAAQAHEF-------IEALPDGydtvvGERgvnlsggqrqRI 485
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 1435 SFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSsaRGALLTTHSMAEAEAvCDRVAIMVSGRLRCIGS 1509
Cdd:COG1132 486 AIARALLKDPPILILDEATSALDTETEALIQEALERLMKG--RTTIVIAHRLSTIRN-ADRILVLDDGRIVEQGT 557
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
500-649 |
9.42e-13 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 72.99 E-value: 9.42e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 500 LQGICLDVYEGQLTAILGHSGAGKSSLLSILGG--WSACTEGSATIYNTQLSEiinmeEIRNYTGFCPQFNIYFDFLTVR 577
Cdd:PLN03211 84 LNGVTGMASPGEILAVLGPSGSGKSTLLNALAGriQGNNFTGTILANNRKPTK-----QILKRTGFVTQDDILYPHLTVR 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 578 ENLrLFAKIKGIPPKEVEQE----VKSIMMELDMHNIQDVIA-----KELSGGQKRKLTFGIAILGDPQVLLLDEPTAGL 648
Cdd:PLN03211 159 ETL-VFCSLLRLPKSLTKQEkilvAESVISELGLTKCENTIIgnsfiRGISGGERKRVSIAHEMLINPSLLILDEPTSGL 237
|
.
gi 1387227070 649 D 649
Cdd:PLN03211 238 D 238
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
1305-1513 |
1.17e-12 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 69.82 E-value: 1.17e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTRQAGGGF-RHLGYCPQEDVLWPDLT 1383
Cdd:PRK10575 24 RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILL--DAQPLESWSSKAFaRKVAYLPQQLPAAEGMT 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1384 VREHLDLysavkGLTKEEAALSVSRLADALKLQDQMAL----P-----AKALPEGAKRKLSFALSVLGSPALLLLDEPTT 1454
Cdd:PRK10575 102 VRELVAI-----GRYPWHGALGRFGAADREKVEEAISLvglkPlahrlVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTS 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 1455 GMDPEGQLQMWQAIQAIvkSSARGALLTT--HSMAEAEAVCDRVAIMVSGRLRCIGSVQHL 1513
Cdd:PRK10575 177 ALDIAHQVDVLALVHRL--SQERGLTVIAvlHDINMAARYCDYLVALRGGEMIAQGTPAEL 235
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
481-698 |
1.27e-12 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 69.61 E-value: 1.27e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKgkpeKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLS---------EI 551
Cdd:PRK10619 6 LNVIDLHKRYG----EHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINlvrdkdgqlKV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 552 INMEEIR----NYTGFCPQFNIYfDFLTVRENLrLFAKIKGIPPKEVEQEVKSIMMeLDMHNI----QDVIAKELSGGQK 623
Cdd:PRK10619 82 ADKNQLRllrtRLTMVFQHFNLW-SHMTVLENV-MEAPIQVLGLSKQEARERAVKY-LAKVGIderaQGKYPVHLSGGQQ 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 624 RKLTFGIAILGDPQVLLLDEPTAGLDPfsrHLVWNFL----KERKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAG 698
Cdd:PRK10619 159 QRVSIARALAMEPEVLLFDEPTSALDP---ELVGEVLrimqQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEG 234
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
1311-1457 |
1.27e-12 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 69.48 E-value: 1.27e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1311 VSFCINKGEVLGLLGHNGAGKSTCIKMITGDTkPTAGVVVFRD---SGTPPTRQAgggfRHLGYCPQEDVLWPDLTVREH 1387
Cdd:COG4138 15 ISAQVNAGELIHLIGPNGAGKSTLLARMAGLL-PGQGEILLNGrplSDWSAAELA----RHRAYLSQQQSPPFAMPVFQY 89
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 1388 LDLYSAvKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVL-------GSPALLLLDEPTTGMD 1457
Cdd:COG4138 90 LALHQP-AGASSEAVEQLLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLqvwptinPEGQLLLLDEPMNSLD 165
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
1309-1496 |
1.39e-12 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 66.70 E-value: 1.39e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1309 RNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVvfrdsgtpptrQAGGGFRhLGYCPQedvlwpdltvrehl 1388
Cdd:cd03221 17 KDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIV-----------TWGSTVK-IGYFEQ-------------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1389 dlysavkgltkeeaaLSvsrladalklqdqmalpakalpEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQlqmwQAI 1468
Cdd:cd03221 71 ---------------LS----------------------GGEKMRLALAKLLLENPNLLLLDEPTNHLDLESI----EAL 109
|
170 180
....*....|....*....|....*...
gi 1387227070 1469 QAIVKSSARGALLTTHSMAEAEAVCDRV 1496
Cdd:cd03221 110 EEALKEYPGTVILVSHDRYFLDQVATKI 137
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
1304-1504 |
1.77e-12 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 71.97 E-value: 1.77e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1304 TKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFR----DSGTPPTRQAGGgfrhLGYCP---QED 1376
Cdd:COG1129 264 VGGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDgkpvRIRSPRDAIRAG----IAYVPedrKGE 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1377 VLWPDLTVRE-----HLDLYSAvKGL--TKEEAALsVSRLADAL--KLQDqMALPAKALPEGAKRKLSFALSVLGSPALL 1447
Cdd:COG1129 340 GLVLDLSIREnitlaSLDRLSR-GGLldRRRERAL-AEEYIKRLriKTPS-PEQPVGNLSGGNQQKVVLAKWLATDPKVL 416
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1448 LLDEPTTGMDPEGQlqmwQAIQAIVKSSAR---GALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:COG1129 417 ILDEPTRGIDVGAK----AEIYRLIRELAAegkAVIVISSELPELLGLSDRILVMREGRI 472
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
1307-1522 |
1.79e-12 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 71.22 E-value: 1.79e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTRQAGGGFRH-----LGYCPQEDVLWPD 1381
Cdd:PRK10070 43 GVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLI--DGVDIAKISDAELREvrrkkIAMVFQSFALMPH 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 LTVREHLDLYSAVKGLTKEEaalsvsRLADALKLQDQMALPAKA------LPEGAKRKLSFALSVLGSPALLLLDEPTTG 1455
Cdd:PRK10070 121 MTVLDNTAFGMELAGINAEE------RREKALDALRQVGLENYAhsypdeLSGGMRQRVGLARALAINPDILLMDEAFSA 194
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 1456 MDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLKSKFGKDYL 1522
Cdd:PRK10070 195 LDPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYV 261
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
500-649 |
1.93e-12 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 67.90 E-value: 1.93e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 500 LQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEI--INMEEIRnYTGFCPQFNiyfDFLTVR 577
Cdd:cd03231 16 FSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQrdSIARGLL-YLGHAPGIK---TTLSVL 91
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 578 ENLRLFAKIKGippkevEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLD 649
Cdd:cd03231 92 ENLRFWHADHS------DEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALD 157
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
1305-1503 |
3.49e-12 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 71.45 E-value: 3.49e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPPTRQAgggFRHLGYCPQEDVLWPDLTV 1384
Cdd:PLN03211 81 RTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNNFTGTILANNRKPTKQI---LKRTGFVTQDDILYPHLTV 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1385 REHLDLYSAV---KGLTKEE---AALSVSRLADALKLQDQMALPA--KALPEGAKRKLSFALSVLGSPALLLLDEPTTGM 1456
Cdd:PLN03211 158 RETLVFCSLLrlpKSLTKQEkilVAESVISELGLTKCENTIIGNSfiRGISGGERKRVSIAHEMLINPSLLILDEPTSGL 237
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 1457 DPEGQLQMwqaIQAIVKSSARGALLTThSMAEAEA----VCDRVAIMVSGR 1503
Cdd:PLN03211 238 DATAAYRL---VLTLGSLAQKGKTIVT-SMHQPSSrvyqMFDSVLVLSEGR 284
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
481-694 |
3.79e-12 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 67.59 E-value: 3.79e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEkveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINMEE--IR 558
Cdd:PRK10908 2 IRFEHVSKAYLGGRQ---ALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNREVpfLR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 559 NYTGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQV 638
Cdd:PRK10908 79 RQIGMIFQDHHLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAV 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 639 LLLDEPTAGLD-PFSRHLVWNFLKERKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:PRK10908 159 LLADEPTGNLDdALSEGILRLFEEFNRVGVTVLMATHDIGLISRRSYRMLTLSDGHL 215
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
1309-1508 |
4.52e-12 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 69.67 E-value: 4.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1309 RNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF---RDSGTPPTRqagggfRHLGYCPQEDVLWPDLTVR 1385
Cdd:PRK11000 20 KDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIgekRMNDVPPAE------RGVGMVFQSYALYPHLSVA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1386 EHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMW 1465
Cdd:PRK11000 94 ENMSFGLKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAALRVQMR 173
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1387227070 1466 QAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIG 1508
Cdd:PRK11000 174 IEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVG 216
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
1306-1513 |
5.25e-12 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 69.36 E-value: 5.25e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1306 TAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGvVVFRDSG--TPPTRQAgggfRHLGYCPQEDVLWPDLT 1383
Cdd:PRK11432 20 TVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEG-QIFIDGEdvTHRSIQQ----RDICMVFQSYALFPHMS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1384 VREHLDLYSAVKGLTKEEAAlsvSRLADALKLQDQMALPAKALPE---GAKRKLSFALSVLGSPALLLLDEPTTGMDPEG 1460
Cdd:PRK11432 95 LGENVGYGLKMLGVPKEERK---QRVKEALELVDLAGFEDRYVDQisgGQQQRVALARALILKPKVLLFDEPLSNLDANL 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 1461 QLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHL 1513
Cdd:PRK11432 172 RRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQEL 224
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
1290-1551 |
7.56e-12 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 68.12 E-value: 7.56e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1290 EYKQEKKRCFSARktktAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD----SGT-----PPTR 1360
Cdd:PRK13634 9 EHRYQYKTPFERR----ALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGErvitAGKknkklKPLR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1361 QagggfrHLGYCPQ--EDVLWPDlTVREHLDLYSAVKGLTKEEAalsvsrLADALKLQDQMALPAKALPE-------GAK 1431
Cdd:PRK13634 85 K------KVGIVFQfpEHQLFEE-TVEKDICFGPMNFGVSEEDA------KQKAREMIELVGLPEELLARspfelsgGQM 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1432 RKLSFAlSVLG-SPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGS- 1509
Cdd:PRK13634 152 RRVAIA-GVLAmEPEVLVLDEPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTp 230
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 1510 -----------------------VQHLKSKFGkdylleVKVKALTL-VEPLHMEILKLFPQAARQE 1551
Cdd:PRK13634 231 reifadpdeleaigldlpetvkfKRALEEKFG------ISFPKPCLtLEELAHEVVQLLRKGGHES 290
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
1278-1503 |
9.63e-12 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 67.26 E-value: 9.63e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1278 DEPVIMASCLHKEYKQEKkrcfsarktktAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTP 1357
Cdd:PRK11701 3 DQPLLSVRGLTKLYGPRK-----------GCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDGQ 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1358 PTRQAGGG---FRHL-----GYCPQ--EDVLWPDLT----VREHLdlySAVK----GLTKEEAALSVSRLA-DALKLQDq 1418
Cdd:PRK11701 72 LRDLYALSeaeRRRLlrtewGFVHQhpRDGLRMQVSaggnIGERL---MAVGarhyGDIRATAGDWLERVEiDAARIDD- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1419 maLPAkALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAI 1498
Cdd:PRK11701 148 --LPT-TFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLV 224
|
....*
gi 1387227070 1499 MVSGR 1503
Cdd:PRK11701 225 MKQGR 229
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
1303-1519 |
1.10e-11 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 70.14 E-value: 1.10e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1303 KTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDT----KPTAGVVVFrdSGTPP---TRQAGGgfrHLGYCPQE 1375
Cdd:TIGR00956 72 KTFDILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIASNTdgfhIGVEGVITY--DGITPeeiKKHYRG---DVVYNAET 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1376 DVLWPDLTVREHLDLYSA-------VKGLTKEEAALSVSRLADAL---------KLQDQMalpAKALPEGAKRKLSFALS 1439
Cdd:TIGR00956 147 DVHFPHLTVGETLDFAARcktpqnrPDGVSREEYAKHIADVYMATyglshtrntKVGNDF---VRGVSGGERKRVSIAEA 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1440 VLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAE-AEAVCDRVAIMVSGRLRCIGSVQHLKSKFG 1518
Cdd:TIGR00956 224 SLGGAKIQCWDNATRGLDSATALEFIRALKTSANILDTTPLVAIYQCSQdAYELFDKVIVLYEGYQIYFGPADKAKQYFE 303
|
.
gi 1387227070 1519 K 1519
Cdd:TIGR00956 304 K 304
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
500-656 |
1.13e-11 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 66.28 E-value: 1.13e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 500 LQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiINMEEIRNYTGFCPQFNIYF-DflTVRE 578
Cdd:PRK10247 23 LNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDIST-LKPEIYRQQVSYCAQTPTLFgD--TVYD 99
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 579 NLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAkELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLV 656
Cdd:PRK10247 100 NLIFPWQIRNQQPDPAIFLDDLERFALPDTILTKNIA-ELSGGEKQRISLIRNLQFMPKVLLLDEITSALDESNKHNV 176
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
1312-1515 |
1.51e-11 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 66.14 E-value: 1.51e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1312 SFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDS---GTPPTRqagggfRHLGYCPQEDVLWPDLTVREH- 1387
Cdd:PRK10771 19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQdhtTTPPSR------RPVSMLFQENNLFSHLTVAQNi 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1388 -LDLYSAVKgLTKEEAAlSVSRLADALKLQDQMA-LPAkALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMW 1465
Cdd:PRK10771 93 gLGLNPGLK-LNAAQRE-KLHAIARQMGIEDLLArLPG-QLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEML 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1466 QAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLKS 1515
Cdd:PRK10771 170 TLVSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDELLS 219
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
1278-1369 |
1.56e-11 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 67.45 E-value: 1.56e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1278 DEPVIMASCLHKEYkqEKKRCFSARKTKT--AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRdsG 1355
Cdd:COG4608 4 AEPLLEVRDLKKHF--PVRGGLFGRTVGVvkAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFD--G 79
|
90
....*....|....
gi 1387227070 1356 TPPTRQAGGGFRHL 1369
Cdd:COG4608 80 QDITGLSGRELRPL 93
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
505-703 |
1.77e-11 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 67.82 E-value: 1.77e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 505 LDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYntqlSEIINMEEIRNyTGFCPQFNIY--FDFLTVRENLRL 582
Cdd:PRK11432 27 LTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFID----GEDVTHRSIQQ-RDICMVFQSYalFPHMSLGENVGY 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 583 FAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE 662
Cdd:PRK11432 102 GLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRE 181
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 663 --RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGS---------SLFL 703
Cdd:PRK11432 182 lqQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSpqelyrqpaSRFM 233
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
1315-1500 |
1.98e-11 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 68.66 E-value: 1.98e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1315 INKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSgtpptrqagggfrhLGYCPQE---DVlwpDLTVREHldLY 1391
Cdd:COG1245 363 IREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDLK--------------ISYKPQYispDY---DGTVEEF--LR 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1392 SAVKGltkeeaALSVS----RLADALKLQDQMALPAKALPEGAKRKLSFALSvLGSPA-LLLLDEPTTGMDPEGQLQMWQ 1466
Cdd:COG1245 424 SANTD------DFGSSyyktEIIKPLGLEKLLDKNVKDLSGGELQRVAIAAC-LSRDAdLYLLDEPSAHLDVEQRLAVAK 496
|
170 180 190
....*....|....*....|....*....|....
gi 1387227070 1467 AIQAIVKSSARGALLTTHSMAEAEAVCDRvaIMV 1500
Cdd:COG1245 497 AIRRFAENRGKTAMVVDHDIYLIDYISDR--LMV 528
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
1302-1523 |
2.39e-11 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 65.64 E-value: 2.39e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1302 RKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF-----RDSGTPPTRqagggfRHLGYCPQED 1376
Cdd:cd03249 13 RPDVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLdgvdiRDLNLRWLR------SQIGLVSQEP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1377 VLWpDLTVREHLdLYSAvKGLTKEEAAlSVSRLADALKLqdQMALP----------AKALPEGAKRKLSFALSVLGSPAL 1446
Cdd:cd03249 87 VLF-DGTIAENI-RYGK-PDATDEEVE-EAAKKANIHDF--IMSLPdgydtlvgerGSQLSGGQKQRIAIARALLRNPKI 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 1447 LLLDEPTTGMDPEGQLQMWQAIQAIVKSsaRGALLTTHSMAEAEAvCDRVAIMVSGRLRCIGSVQHLKSKFGKDYLL 1523
Cdd:cd03249 161 LLLDEATSALDAESEKLVQEALDRAMKG--RTTIVIAHRLSTIRN-ADLIAVLQNGQVVEQGTHDELMAQKGVYAKL 234
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
476-649 |
2.66e-11 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 67.99 E-value: 2.66e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 476 HRkEAIRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSatiynTQLSEIINMe 555
Cdd:PRK15064 316 HR-NALEVENLTKGFDNGP----LFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGT-----VKWSENANI- 384
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 556 eirnytGFCPQfNIYFDF---LTVRENLRLFAKikgipPKEVEQEVKSIMMELDMHniQDVI---AKELSGGQKRKLTFG 629
Cdd:PRK15064 385 ------GYYAQ-DHAYDFendLTLFDWMSQWRQ-----EGDDEQAVRGTLGRLLFS--QDDIkksVKVLSGGEKGRMLFG 450
|
170 180
....*....|....*....|
gi 1387227070 630 IAILGDPQVLLLDEPTAGLD 649
Cdd:PRK15064 451 KLMMQKPNVLVMDEPTNHMD 470
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
1305-1560 |
3.14e-11 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 65.96 E-value: 3.14e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF---------RDSGTPPTRQAGGgfrhLGYCPQE 1375
Cdd:PRK13646 20 HQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVdditithktKDKYIRPVRKRIG----MVFQFPE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1376 DVLWPDlTVREHLDLYSAVKGLTKEEAALSVSRLADALKL-QDQMALPAKALPEGAKRKLSFaLSVLG-SPALLLLDEPT 1453
Cdd:PRK13646 96 SQLFED-TVEREIIFGPKNFKMNLDEVKNYAHRLLMDLGFsRDVMSQSPFQMSGGQMRKIAI-VSILAmNPDIIVLDEPT 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1454 TGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLKSKfgKDYLLEVKVkALTLV 1533
Cdd:PRK13646 174 AGLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFKD--KKKLADWHI-GLPEI 250
|
250 260 270
....*....|....*....|....*....|.
gi 1387227070 1534 EPLHMEILK----LFPQAARQERySFVMAYK 1560
Cdd:PRK13646 251 VQLQYDFEQkyqtKLKDIALTEE-EFVSLYK 280
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
499-674 |
3.52e-11 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 65.67 E-value: 3.52e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 499 ALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIyntqLSEIINMEEIRNYTGFCPQFN-IYFDFLTVR 577
Cdd:PRK15056 22 ALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISI----LGQPTRQALQKNLVAYVPQSEeVDWSFPVLV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 578 ENLRLFAKIKG-----IPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFS 652
Cdd:PRK15056 98 EDVVMMGRYGHmgwlrRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVKT 177
|
170 180
....*....|....*....|...
gi 1387227070 653 RHLVWNFLKE-RKTNHTILFSTQ 674
Cdd:PRK15056 178 EARIISLLRElRDEGKTMLVSTH 200
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
1307-1503 |
4.08e-11 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 65.53 E-value: 4.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAG-VVVFRDSGTPPTRQAGGGFRHLGYCPQEDVLWPDlTVR 1385
Cdd:PRK13647 20 ALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGrVKVMGREVNAENEKWVRSKVGLVFQDPDDQVFSS-TVW 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1386 EHLDLYSAVKGLTKEEAAlsvSRLADALKLQDQMALPAKA---LPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQL 1462
Cdd:PRK13647 99 DDVAFGPVNMGLDKDEVE---RRVEEALKAVRMWDFRDKPpyhLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQE 175
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1387227070 1463 QMwQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGR 1503
Cdd:PRK13647 176 TL-MEILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEGR 215
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
478-694 |
4.18e-11 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 63.61 E-value: 4.18e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 478 KEAIRIRNLRKEYkgkpekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIyntqlseiiNMEEI 557
Cdd:cd03215 2 EPVLEVRGLSVKG--------AVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITL---------DGKPV 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 558 RnytgfcpqfniyfdFLTVRENLRLfakikGIP--PKEVEQEvkSIMMELD-MHNIqdVIAKELSGGQKRKLTFGIAILG 634
Cdd:cd03215 65 T--------------RRSPRDAIRA-----GIAyvPEDRKRE--GLVLDLSvAENI--ALSSLLSGGNQQKVVLARWLAR 121
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 635 DPQVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:cd03215 122 DPRVLILDEPTRGVDVGAKAEIYRLIRElADAGKAVLLISSELDELLGLCDRILVMYEGRI 182
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
1311-1457 |
4.51e-11 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 64.95 E-value: 4.51e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1311 VSFCINKGEVLGLLGHNGAGKSTCIKMITGdTKPTAGVVVFRD---SGTPPTRQAgggfRHLGYCPQEDVLWPDLTVREH 1387
Cdd:PRK03695 15 LSAEVRAGEILHLVGPNGAGKSTLLARMAG-LLPGSGSIQFAGqplEAWSAAELA----RHRAYLSQQQTPPFAMPVFQY 89
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 1388 LDLYSAVKGLTKEEAALsVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVL-----GSPA--LLLLDEPTTGMD 1457
Cdd:PRK03695 90 LTLHQPDKTRTEAVASA-LNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAAVVLqvwpdINPAgqLLLLDEPMNSLD 165
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
1304-1496 |
4.52e-11 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 64.35 E-value: 4.52e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1304 TKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPT--RQagggfrHLGYCPQEDVL 1378
Cdd:PRK10247 19 DAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGediSTLKPEiyRQ------QVSYCAQTPTL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1379 WPDlTVREHLDLYSAVKGLTKEEAAL--SVSRLADALKLQDQmalPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGM 1456
Cdd:PRK10247 93 FGD-TVYDNLIFPWQIRNQQPDPAIFldDLERFALPDTILTK---NIAELSGGEKQRISLIRNLQFMPKVLLLDEITSAL 168
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1387227070 1457 DPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAvCDRV 1496
Cdd:PRK10247 169 DESNKHNVNEIIHRYVREQNIAVLWVTHDKDEINH-ADKV 207
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
1307-1509 |
6.31e-11 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 63.59 E-value: 6.31e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF--RDSGTPPTRQAGggfRHLGYCPQEDVLWpDLTV 1384
Cdd:cd03369 23 VLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIdgIDISTIPLEDLR---SSLTIIPQDPTLF-SGTI 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1385 REHLDLYSAvkgLTKEE--AALSVSRLADALKlqdqmalpakalpEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQl 1462
Cdd:cd03369 99 RSNLDPFDE---YSDEEiyGALRVSEGGLNLS-------------QGQRQLLCLARALLKRPRVLVLDEATASIDYATD- 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 1463 qmwQAIQAIVKSSARGALLTT-----HSMAEaeavCDRVAIMVSGRLRCIGS 1509
Cdd:cd03369 162 ---ALIQKTIREEFTNSTILTiahrlRTIID----YDKILVMDAGEVKEYDH 206
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
1298-1518 |
6.88e-11 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 64.17 E-value: 6.88e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1298 CFSARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF-----RDSGTPPTRqagggfRHLGYC 1372
Cdd:cd03253 7 TFAYDPGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIdgqdiREVTLDSLR------RAIGVV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1373 PQEDVLWPDlTVREHLdLYSAVKGlTKEEaalsVSRLADALKLQDQ-MALPAK----------ALPEGAKRKLSFALSVL 1441
Cdd:cd03253 81 PQDTVLFND-TIGYNI-RYGRPDA-TDEE----VIEAAKAAQIHDKiMRFPDGydtivgerglKLSGGEKQRVAIARAIL 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 1442 GSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSsaRGALLTTHSMAEAeAVCDRVAIMVSGRLRCIGSVQHLKSKFG 1518
Cdd:cd03253 154 KNPPILLLDEATSALDTHTEREIQAALRDVSKG--RTTIVIAHRLSTI-VNADKIIVLKDGRIVERGTHEELLAKGG 227
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
1309-1504 |
7.06e-11 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 66.61 E-value: 7.06e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1309 RNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD----SGTPPTRQAGGgfrhLGYCPqEDvlwpdltv 1384
Cdd:PRK15439 280 RNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGkeinALSTAQRLARG----LVYLP-ED-------- 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1385 RE----HLD--LYSAVKGLT-----------KEEAALSVSRLADALKLQ--DQmalPAKALPEGAKRKLSFALSVLGSPA 1445
Cdd:PRK15439 347 RQssglYLDapLAWNVCALThnrrgfwikpaRENAVLERYRRALNIKFNhaEQ---AARTLSGGNQQKVLIAKCLEASPQ 423
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 1446 LLLLDEPTTGMDPEGQLQMWQAIQAIVKSSArGALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:PRK15439 424 LLIVDEPTRGVDVSARNDIYQLIRSIAAQNV-AVLFISSDLEEIEQMADRVLVMHQGEI 481
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
481-649 |
7.71e-11 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 64.26 E-value: 7.71e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINMEEIRnY 560
Cdd:PRK11231 3 LRTENLTVGYGTKR----ILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLAR-R 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDFLTVRE--------NLRLFAKIKGippkEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAI 632
Cdd:PRK11231 78 LALLPQHHLTPEGITVRElvaygrspWLSLWGRLSA----EDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVL 153
|
170
....*....|....*..
gi 1387227070 633 LGDPQVLLLDEPTAGLD 649
Cdd:PRK11231 154 AQDTPVVLLDEPTTYLD 170
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
1280-1484 |
8.10e-11 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 63.82 E-value: 8.10e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1280 PVIMASCLHKEYKQEKKRCFSAR------------KTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITG--DTKPT 1345
Cdd:COG2401 6 PFFVLMRVTKVYSSVLDLSERVAivleafgvelrvVERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGalKGTPV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1346 AGVVVFRDsgtpptrqagggfrhlgycpqeDVLWPDLTVREHLDLysavkgltKEEAALSVSRLADAlKLQDQMAL--PA 1423
Cdd:COG2401 86 AGCVDVPD----------------------NQFGREASLIDAIGR--------KGDFKDAVELLNAV-GLSDAVLWlrRF 134
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 1424 KALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTH 1484
Cdd:COG2401 135 KELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQTAKRVARNLQKLARRAGITLVVATH 195
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
1308-1457 |
9.50e-11 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 67.18 E-value: 9.50e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1308 VRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGdtKPTAGVVV--FRDSGTPPTRQAGGgfRHLGYCPQEDVLWPDLTVR 1385
Cdd:PLN03140 896 LREVTGAFRPGVLTALMGVSGAGKTTLMDVLAG--RKTGGYIEgdIRISGFPKKQETFA--RISGYCEQNDIHSPQVTVR 971
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1386 EHLdLYSAV----KGLTKEEAALSVSRLADALKLQDQ----MALPA-KALPEGAKRKLSFALSVLGSPALLLLDEPTTGM 1456
Cdd:PLN03140 972 ESL-IYSAFlrlpKEVSKEEKMMFVDEVMELVELDNLkdaiVGLPGvTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGL 1050
|
.
gi 1387227070 1457 D 1457
Cdd:PLN03140 1051 D 1051
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
1306-1513 |
9.91e-11 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 65.13 E-value: 9.91e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1306 TAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITG---DTKPTAGVVVF--RDSGTPPTRQagggfrhLGYCPQEDV--- 1377
Cdd:PRK09473 30 TAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGllaANGRIGGSATFngREILNLPEKE-------LNKLRAEQIsmi 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1378 -------LWPDLTVREHL-DLYSAVKGLTKEEAALSVSRLADALKLQD---QMALPAKALPEGAKRKLSFALSVLGSPAL 1446
Cdd:PRK09473 103 fqdpmtsLNPYMRVGEQLmEVLMLHKGMSKAEAFEESVRMLDAVKMPEarkRMKMYPHEFSGGMRQRVMIAMALLCRPKL 182
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 1447 LLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHL 1513
Cdd:PRK09473 183 LIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDV 249
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
1304-1504 |
1.27e-10 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 63.88 E-value: 1.27e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1304 TKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDS--GTPPTRQAGggfRHLGYCPQEDVLWPD 1381
Cdd:PRK11231 14 TKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKpiSMLSSRQLA---RRLALLPQHHLTPEG 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 LTVRE--------HLDLYSAvkgLTKEEAALsvsrLADALKLQDQMALPAKALPE--GAKRKLSFALSVLGSPA-LLLLD 1450
Cdd:PRK11231 91 ITVRElvaygrspWLSLWGR---LSAEDNAR----VNQAMEQTRINHLADRRLTDlsGGQRQRAFLAMVLAQDTpVVLLD 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 1451 EPTTGMDPEGQLQMWQAIQaivKSSARGALLTT--HSMAEAEAVCDRVAIMVSGRL 1504
Cdd:PRK11231 164 EPTTYLDINHQVELMRLMR---ELNTQGKTVVTvlHDLNQASRYCDHLVVLANGHV 216
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
1310-1483 |
1.31e-10 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 66.67 E-value: 1.31e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1310 NVSFCINKGEVLGLLGHNGAGKSTCIKMITGdtKPTAGVVvfrdsgTPPTRQAGGG-----F-RHLGYCPQEDVLWPDLT 1383
Cdd:TIGR00956 781 NVDGWVKPGTLTALMGASGAGKTTLLNVLAE--RVTTGVI------TGGDRLVNGRpldssFqRSIGYVQQQDLHLPTST 852
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1384 VREHLDlYSAV----KGLTKEEAALSVSRLADALKLQDQ----MALPAKALPEGAKRKLSFALSVLGSPALLL-LDEPTT 1454
Cdd:TIGR00956 853 VRESLR-FSAYlrqpKSVSKSEKMEYVEEVIKLLEMESYadavVGVPGEGLNVEQRKRLTIGVELVAKPKLLLfLDEPTS 931
|
170 180 190
....*....|....*....|....*....|
gi 1387227070 1455 GMDPEGQlqmWQAIQAIVKSSARG-ALLTT 1483
Cdd:TIGR00956 932 GLDSQTA---WSICKLMRKLADHGqAILCT 958
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
1307-1502 |
1.55e-10 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 63.62 E-value: 1.55e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSgtPPTRQAGGGFR-HLGYCPQEdvlwPDLTVR 1385
Cdd:PRK13648 24 TLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQ--AITDDNFEKLRkHIGIVFQN----PDNQFV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1386 EHLDLYSAVKGLtkEEAALS----VSRLADALK---LQDQMALPAKALPEGAKRKLSFAlSVLG-SPALLLLDEPTTGMD 1457
Cdd:PRK13648 98 GSIVKYDVAFGL--ENHAVPydemHRRVSEALKqvdMLERADYEPNALSGGQKQRVAIA-GVLAlNPSVIILDEATSMLD 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1387227070 1458 PEGQLQMWQAIQAIVKSSARGALLTTHSMAEAeAVCDRVAIMVSG 1502
Cdd:PRK13648 175 PDARQNLLDLVRKVKSEHNITIISITHDLSEA-MEADHVIVMNKG 218
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
1298-1504 |
1.93e-10 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 64.10 E-value: 1.93e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1298 CFSARKTK---TAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD------------SGTPPTRQA 1362
Cdd:PRK13631 29 CVFDEKQEnelVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVGDiyigdkknnhelITNPYSKKI 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1363 GGgFRHL----GYCPQ--EDVLWPDlTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQ-MALPAKALPEGAKRKLS 1435
Cdd:PRK13631 109 KN-FKELrrrvSMVFQfpEYQLFKD-TIEKDIMFGPVALGVKKSEAKKLAKFYLNKMGLDDSyLERSPFGLSGGQKRRVA 186
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 1436 FALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAiVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:PRK13631 187 IAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILD-AKANNKTVFVITHTMEHVLEVADEVIVMDKGKI 254
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
1301-1510 |
2.36e-10 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 63.31 E-value: 2.36e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1301 ARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGD-TKPTA--GVVVFRD---SGTP-----PTRQAgggfRHL 1369
Cdd:PRK13547 10 ARRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDlTGGGAprGARVTGDvtlNGEPlaaidAPRLA----RLR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1370 GYCPQEDVLWPDLTVRE--------HLDLYSAVKGLTKEEAALSVSRL-ADALKLQDQMALPAKALpegAKRKLSFALSV 1440
Cdd:PRK13547 86 AVLPQAAQPAFAFSAREivllgrypHARRAGALTHRDGEIAWQALALAgATALVGRDVTTLSGGEL---ARVQFARVLAQ 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 1441 L-------GSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSV 1510
Cdd:PRK13547 163 LwpphdaaQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAP 239
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
469-694 |
2.41e-10 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 65.05 E-value: 2.41e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 469 EPVSPEFHRKEA------IRIRNLRkeYKGkPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSAT 542
Cdd:COG3845 240 REVLLRVEKAPAepgevvLEVENLS--VRD-DRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIR 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 543 IYNTQLS-----EIINM------EEiRNYTGFCPQFniyfdflTVRENLRL-------FAKIKGIPPKEVEQEVKSIMME 604
Cdd:COG3845 317 LDGEDITglsprERRRLgvayipED-RLGRGLVPDM-------SVAENLILgryrrppFSRGGFLDRKAIRAFAEELIEE 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 605 LDmhnIQ----DVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEA 679
Cdd:COG3845 389 FD---VRtpgpDTPARSLSGGNQQKVILARELSRDPKLLIAAQPTRGLDVGAIEFIHQRLLElRDAGAAVLLISEDLDEI 465
|
250
....*....|....*
gi 1387227070 680 DILADRKVFLSNGKL 694
Cdd:COG3845 466 LALSDRIAVMYEGRI 480
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
1315-1500 |
2.45e-10 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 65.21 E-value: 2.45e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1315 INKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSgtpptrqagggfrhLGYCPQEDVLWPDLTVREHldLYSAV 1394
Cdd:PRK13409 362 IYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPELK--------------ISYKPQYIKPDYDGTVEDL--LRSIT 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1395 KGLT----KEEaalsvsrLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQA 1470
Cdd:PRK13409 426 DDLGssyyKSE-------IIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRR 498
|
170 180 190
....*....|....*....|....*....|
gi 1387227070 1471 IVKSSARGALLTTHSMAEAEAVCDRvaIMV 1500
Cdd:PRK13409 499 IAEEREATALVVDHDIYMIDYISDR--LMV 526
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
481-713 |
2.64e-10 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 65.13 E-value: 2.64e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEkVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRNY 560
Cdd:TIGR00958 479 IEFQDVSFSYPNRPD-VPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQY-DHHYLHRQ 556
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQFNIYFDfLTVRENLrlfakIKGIPPKEVEQevksIMMELDMHNIQDVIAK--------------ELSGGQKRKL 626
Cdd:TIGR00958 557 VALVGQEPVLFS-GSVRENI-----AYGLTDTPDEE----IMAAAKAANAHDFIMEfpngydtevgekgsQLSGGQKQRI 626
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 627 TFGIAILGDPQVLLLDEPTAGLDPFSRHLV--WNFLKERktnhTILFSTQFMDEADiLADRKVFLSNGKLRCAGSSLFLK 704
Cdd:TIGR00958 627 AIARALVRKPRVLILDEATSALDAECEQLLqeSRSRASR----TVLLIAHRLSTVE-RADQILVLKKGSVVEMGTHKQLM 701
|
....*....
gi 1387227070 705 RKWGIGYHL 713
Cdd:TIGR00958 702 EDQGCYKHL 710
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
1302-1502 |
2.85e-10 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 62.98 E-value: 2.85e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1302 RKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSgtpPTRQAgggFRH--LGYCPQ-EDVL 1378
Cdd:PRK15056 17 RNGHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQ---PTRQA---LQKnlVAYVPQsEEVD 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1379 WPDLTVREHLDL---YSAVkGLTKEEAALSVSRLADALKLQDQMALPAKALPE---GAKRKLSFALSVLGSPALLLLDEP 1452
Cdd:PRK15056 91 WSFPVLVEDVVMmgrYGHM-GWLRRAKKRDRQIVTAALARVDMVEFRHRQIGElsgGQKKRVFLARAIAQQGQVILLDEP 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1453 TTGMDPEGQLQMWQAIQAIvKSSARGALLTTHSMAEAEAVCDrVAIMVSG 1502
Cdd:PRK15056 170 FTGVDVKTEARIISLLREL-RDEGKTMLVSTHNLGSVTEFCD-YTVMVKG 217
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
481-694 |
2.87e-10 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 62.90 E-value: 2.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYK-----GKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNME 555
Cdd:TIGR02769 3 LEVRDVTHTYRtgglfGAKQRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQL-DRK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 556 EIR------------NYTGFCPQFNIYFdflTVRENLRLFAKIKgippkEVEQEVKSIMMeLDMHNIQDVIAK----ELS 619
Cdd:TIGR02769 82 QRRafrrdvqlvfqdSPSAVNPRMTVRQ---IIGEPLRHLTSLD-----ESEQKARIAEL-LDMVGLRSEDADklprQLS 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 620 GGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTI--LFSTQFMDEADILADRKVFLSNGKL 694
Cdd:TIGR02769 153 GGQLQRINIARALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTayLFITHDLRLVQSFCQRVAVMDKGQI 229
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
487-693 |
3.10e-10 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 61.51 E-value: 3.10e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 487 RKEYKGKPEKvEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGG---WSACTEGSATiYNTqlseIINMEEIRNYTG- 562
Cdd:cd03233 11 FTTGKGRSKI-PILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANrteGNVSVEGDIH-YNG----IPYKEFAEKYPGe 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 563 --FCPQFNIYFDFLTVRENLRLFAKIKGippkeveqevksimmeldmhniqDVIAKELSGGQKRKLTFGIAILGDPQVLL 640
Cdd:cd03233 85 iiYVSEEDVHFPTLTVRETLDFALRCKG-----------------------NEFVRGISGGERKRVSIAEALVSRASVLC 141
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 641 LDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFS-TQFMDEADILADRKVFLSNGK 693
Cdd:cd03233 142 WDNSTRGLDSSTALEILKCIRTmaDVLKTTTFVSlYQASDEIYDLFDKVLVLYEGR 197
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
1321-1459 |
3.28e-10 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 64.57 E-value: 3.28e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1321 LGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTpptrqagggfrhLGYCPQEDVLWPDLTVREH-----------LD 1389
Cdd:TIGR03719 34 IGVLGLNGAGKSTLLRIMAGVDKDFNGEARPQPGIK------------VGYLPQEPQLDPTKTVRENveegvaeikdaLD 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1390 LYSAV-----------KGLTKEEAAL--------------SVSRLADALKLQDQMAlPAKALPEGAKRKLSFALSVLGSP 1444
Cdd:TIGR03719 102 RFNEIsakyaepdadfDKLAAEQAELqeiidaadawdldsQLEIAMDALRCPPWDA-DVTKLSGGERRRVALCRLLLSKP 180
|
170
....*....|....*
gi 1387227070 1445 ALLLLDEPTTGMDPE 1459
Cdd:TIGR03719 181 DMLLLDEPTNHLDAE 195
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
1308-1504 |
3.60e-10 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 64.25 E-value: 3.60e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1308 VRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrDSGTPPTRQAGGGFRH-LGYCPQE---DVLWPDLT 1383
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTL-DGHEVVTRSPQDGLANgIVYISEDrkrDGLVLGMS 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1384 VREH-----LDLYSAVKG-LTKEEAALSVSRLADALKL----QDQmalPAKALPEGAKRKLSFALSVLGSPALLLLDEPT 1453
Cdd:PRK10762 347 VKENmsltaLRYFSRAGGsLKHADEQQAVSDFIRLFNIktpsMEQ---AIGLLSGGNQQKVAIARGLMTRPKVLILDEPT 423
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 1454 TGMDPEGQLQMWQAIQAIvKSSARGALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:PRK10762 424 RGVDVGAKKEIYQLINQF-KAEGLSIILVSSEMPEVLGMSDRILVMHEGRI 473
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
1305-1504 |
3.82e-10 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 62.90 E-value: 3.82e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITG----DTKPTAGVVVfrdSGTPPTRQAGGGFRH-LGYCPQEdvlw 1379
Cdd:PRK13640 20 KPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGlllpDDNPNSKITV---DGITLTAKTVWDIREkVGIVFQN---- 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1380 PD-----LTVREHLDLYSAVKGLTKEEAALSVSR-LADALKLQDQMALPAKaLPEGAKRKLSFALSVLGSPALLLLDEPT 1453
Cdd:PRK13640 93 PDnqfvgATVGDDVAFGLENRAVPRPEMIKIVRDvLADVGMLDYIDSEPAN-LSGGQKQRVAIAGILAVEPKIIILDEST 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 1454 TGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEaVCDRVAIMVSGRL 1504
Cdd:PRK13640 172 SMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEAN-MADQVLVLDDGKL 221
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
1305-1521 |
3.93e-10 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 62.41 E-value: 3.93e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTP---PTRQAGGGFRHLGYCPQEDVLwpd 1381
Cdd:PRK11248 14 KPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITL--DGKPvegPGAERGVVFQNEGLLPWRNVQ--- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 ltvrEHLDLYSAVKGLTKEEaalsvsRLADALKLQDQMALPAKA------LPEGAKRKLSFALSVLGSPALLLLDEPTTG 1455
Cdd:PRK11248 89 ----DNVAFGLQLAGVEKMQ------RLEIAHQMLKKVGLEGAEkryiwqLSGGQRQRVGIARALAANPQLLLLDEPFGA 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 1456 MDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCigsVQHLKSKFGKDY 1521
Cdd:PRK11248 159 LDAFTREQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSPGPGRV---VERLPLNFARRF 221
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
500-672 |
3.95e-10 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 64.93 E-value: 3.95e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 500 LQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWsACTEGSATIYNTQLSEIiNMEEIRNYTGFCPQfNIYFDFLTVREN 579
Cdd:TIGR01271 1235 LQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRL-LSTEGEIQIDGVSWNSV-TLQTWRKAFGVIPQ-KVFIFSGTFRKN 1311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 580 LRLFAKIKGIPPKEVEQEV--KSIMMEL-DMHNIQDVIAKE-LSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHL 655
Cdd:TIGR01271 1312 LDPYEQWSDEEIWKVAEEVglKSVIEQFpDKLDFVLVDGGYvLSNGHKQLMCLARSILSKAKILLLDEPSAHLDPVTLQI 1391
|
170
....*....|....*..
gi 1387227070 656 VWNFLKERKTNHTILFS 672
Cdd:TIGR01271 1392 IRKTLKQSFSNCTVILS 1408
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
483-649 |
4.66e-10 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 62.01 E-value: 4.66e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 483 IRNLRKEYKGKpekvEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSAC--TEGSATIYNTqlsEIINME-EIRN 559
Cdd:COG0396 3 IKNLHVSVEGK----EILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPKYevTSGSILLDGE---DILELSpDERA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YTGfcpqfnIYFDF--------LTVRENLRLFAKIKG---IPPKEVEQEVKSIMMELDMHniQDVIAKEL----SGGQKR 624
Cdd:COG0396 76 RAG------IFLAFqypveipgVSVSNFLRTALNARRgeeLSAREFLKLLKEKMKELGLD--EDFLDRYVnegfSGGEKK 147
|
170 180
....*....|....*....|....*.
gi 1387227070 625 KL-TFGIAILgDPQVLLLDEPTAGLD 649
Cdd:COG0396 148 RNeILQMLLL-EPKLAILDETDSGLD 172
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
1279-1513 |
4.69e-10 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 62.34 E-value: 4.69e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1279 EPVIMASCLHKEYKQEKkrcfsarktktAVRNVSFCINKGEVLGLLGHNGAGKSTCIK----MITGDTKPTAGVVVFRDS 1354
Cdd:PRK09984 2 QTIIRVEKLAKTFNQHQ-----------ALHAVDLNIHHGEMVALLGPSGSGKSTLLRhlsgLITGDKSAGSHIELLGRT 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1355 GTPPTRQAGGGFR---HLGYCPQEDVLWPDLTVREHLDL------------YSAVKGLTKEEAALSVSRLADALKLQDQM 1419
Cdd:PRK09984 71 VQREGRLARDIRKsraNTGYIFQQFNLVNRLSVLENVLIgalgstpfwrtcFSWFTREQKQRALQALTRVGMVHFAHQRV 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1420 AlpakALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIM 1499
Cdd:PRK09984 151 S----TLSGGQQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVAL 226
|
250
....*....|....
gi 1387227070 1500 VSGRLRCIGSVQHL 1513
Cdd:PRK09984 227 RQGHVFYDGSSQQF 240
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
1310-1525 |
5.06e-10 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 63.18 E-value: 5.06e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1310 NVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTRQAGGGfRHLGYCPQEDVLWPDLTVREHLD 1389
Cdd:PRK10851 20 DISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRF--HGTDVSRLHARD-RKVGFVFQHYALFRHMTVFDNIA 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1390 LysavkGLT-------KEEAALS--VSRLADALKLqDQMA--LPAKaLPEGAKRKLSFALSVLGSPALLLLDEPTTGMDP 1458
Cdd:PRK10851 97 F-----GLTvlprrerPNAAAIKakVTQLLEMVQL-AHLAdrYPAQ-LSGGQKQRVALARALAVEPQILLLDEPFGALDA 169
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 1459 E--GQLQMW--QAIQAIVKSSargaLLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHL----KSKFGKDYLLEV 1525
Cdd:PRK10851 170 QvrKELRRWlrQLHEELKFTS----VFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVwrepATRFVLEFMGEV 240
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
1306-1503 |
5.50e-10 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 63.69 E-value: 5.50e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1306 TAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGdTKPTA---GVVVF-----RDSGTPPTRQAGGGFRHlgycpQEDV 1377
Cdd:TIGR02633 15 KALDGIDLEVRPGECVGLCGENGAGKSTLMKILSG-VYPHGtwdGEIYWsgsplKASNIRDTERAGIVIIH-----QELT 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1378 LWPDLTVREHLDLYSAV--KGLTKEEAA--LSVSRLADALKLQ-DQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEP 1452
Cdd:TIGR02633 89 LVPELSVAENIFLGNEItlPGGRMAYNAmyLRAKNLLRELQLDaDNVTRPVGDYGGGQQQLVEIAKALNKQARLLILDEP 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 1453 TTGMdPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGR 1503
Cdd:TIGR02633 169 SSSL-TEKETEILLDIIRDLKAHGVACVYISHKLNEVKAVCDTICVIRDGQ 218
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
1291-1517 |
5.94e-10 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 61.76 E-value: 5.94e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1291 YKQEKKRC------FSARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPPTRQAGg 1364
Cdd:PRK13546 17 YRTNKERMkdalipKHKNKTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGEVSVIAISAG- 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1365 gfrhlgycpqedvLWPDLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSP 1444
Cdd:PRK13546 96 -------------LSGQLTGIENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNP 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 1445 ALLLLDEPTTGMDPEGQLQMWQAIQAIvKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLKSKF 1517
Cdd:PRK13546 163 DILVIDEALSVGDQTFAQKCLDKIYEF-KEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPKY 234
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
1302-1518 |
6.36e-10 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 63.97 E-value: 6.36e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1302 RKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSgtpPTRQAGGGF--RHLGYCPQEDVLW 1379
Cdd:TIGR00958 491 RPDVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGV---PLVQYDHHYlhRQVALVGQEPVLF 567
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1380 PDlTVREHLdLYsavkGLTK--EEAALSVSRLADALKLQDQM--------ALPAKALPEGAKRKLSFALSVLGSPALLLL 1449
Cdd:TIGR00958 568 SG-SVRENI-AY----GLTDtpDEEIMAAAKAANAHDFIMEFpngydtevGEKGSQLSGGQKQRIAIARALVRKPRVLIL 641
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 1450 DEPTTGMDPEGQlqmwQAIQAIVKSSARGALLTTHSMAEAEAvCDRVAIMVSGRLRCIGSVQHLKSKFG 1518
Cdd:TIGR00958 642 DEATSALDAECE----QLLQESRSRASRTVLLIAHRLSTVER-ADQILVLKKGSVVEMGTHKQLMEDQG 705
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
1305-1509 |
8.38e-10 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 60.59 E-value: 8.38e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCI----KM-------ITGDTKPTAGVvvfrdsGTPPTRQagggfrHLGYCP 1373
Cdd:cd03244 17 PPVLKNISFSIKPGEKVGIVGRTGSGKSSLLlalfRLvelssgsILIDGVDISKI------GLHDLRS------RISIIP 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1374 QEDVLWPDlTVREHLDLYSAVkglTKEE--AALSVSRLADAL-----KLQDQMALPAKALPEGAKRKLSFALSVLGSPAL 1446
Cdd:cd03244 85 QDPVLFSG-TIRSNLDPFGEY---SDEElwQALERVGLKEFVeslpgGLDTVVEEGGENLSVGQRQLLCLARALLRKSKI 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 1447 LLLDEPTTGMDPEGQlqmwQAIQAIVKSSARGALLTT-----HSMAEaeavCDRVAIMVSGRLRCIGS 1509
Cdd:cd03244 161 LVLDEATASVDPETD----ALIQKTIREAFKDCTVLTiahrlDTIID----SDRILVLDKGRVVEFDS 220
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
1306-1504 |
1.05e-09 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 60.88 E-value: 1.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1306 TAVRNVSFCINKGEVLGLLGHNGAGKST---CI---KMIT-GD--------TKPTAGVVVFRdsgtpptRQAGGGFrhlg 1370
Cdd:PRK09493 15 QVLHNIDLNIDQGEVVVIIGPSGSGKSTllrCInklEEITsGDlivdglkvNDPKVDERLIR-------QEAGMVF---- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1371 ycpQEDVLWPDLTVREHLDLYSA-VKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLL 1449
Cdd:PRK09493 84 ---QQFYLFPHLTALENVMFGPLrVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLF 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 1450 DEPTTGMDPEGQLQMWQAIQAIVKSSARgALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:PRK09493 161 DEPTSALDPELRHEVLKVMQDLAEEGMT-MVIVTHEIGFAEKVASRLIFIDKGRI 214
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
1305-1504 |
1.18e-09 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 62.74 E-value: 1.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRdsGTPPTRQAGGGFRHLG--YCPQE---DVLW 1379
Cdd:COG3845 271 VPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLD--GEDITGLSPRERRRLGvaYIPEDrlgRGLV 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1380 PDLTVREHLdlysAVKGLTKEEAA----LSVSRL-ADALKLQDQM-------ALPAKALPEGAKRKLSFALSVLGSPALL 1447
Cdd:COG3845 349 PDMSVAENL----ILGRYRRPPFSrggfLDRKAIrAFAEELIEEFdvrtpgpDTPARSLSGGNQQKVILARELSRDPKLL 424
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 1448 LLDEPTTGMDPEGQLQMWqaiQAIVKSSARGA--LLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:COG3845 425 IAAQPTRGLDVGAIEFIH---QRLLELRDAGAavLLISEDLDEILALSDRIAVMYEGRI 480
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
1307-1502 |
1.71e-09 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 62.33 E-value: 1.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD-----SGTPPTRQAGGGFRHlgycpQEDVLWPD 1381
Cdd:PRK10762 19 ALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGkevtfNGPKSSQEAGIGIIH-----QELNLIPQ 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 LTVREHL----------------DLYS-AVKGLTKEEAALSVSRLADALKLQD-QMALPAKAlpegakrkLSFALSVlgs 1443
Cdd:PRK10762 94 LTIAENIflgrefvnrfgridwkKMYAeADKLLARLNLRFSSDKLVGELSIGEqQMVEIAKV--------LSFESKV--- 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1444 palLLLDEPTTGM-DPEGQlQMWQAIQAIvKSSARGALLTTHSMAEAEAVCDRVAIMVSG 1502
Cdd:PRK10762 163 ---IIMDEPTDALtDTETE-SLFRVIREL-KSQGRGIVYISHRLKEIFEICDDVTVFRDG 217
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
1311-1505 |
1.80e-09 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 59.79 E-value: 1.80e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1311 VSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVvfRDSGTPPTR-----QAGGGFRHLGYCPQEDVLWPDLTVR 1385
Cdd:PRK10584 29 VELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEV--SLVGQPLHQmdeeaRAKLRAKHVGFVFQSFMLIPTLNAL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1386 EHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMA-LPAKaLPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQM 1464
Cdd:PRK10584 107 ENVELPALLRGESSRQSRNGAKALLEQLGLGKRLDhLPAQ-LSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKI 185
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1387227070 1465 WQAIQAIVKSSARGALLTTHSMAEAeAVCDRVAIMVSGRLR 1505
Cdd:PRK10584 186 ADLLFSLNREHGTTLILVTHDLQLA-ARCDRRLRLVNGQLQ 225
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
1318-1468 |
1.83e-09 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 62.49 E-value: 1.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1318 GEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdsgtpptrqaGGGFRhLGYCPQE--DVLWPDLTVREHLdlysavk 1395
Cdd:PRK10636 338 GSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGL-----------AKGIK-LGYFAQHqlEFLRADESPLQHL------- 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1396 gltkeeaalsvSRLADALKLQ-------------DQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDpegqL 1462
Cdd:PRK10636 399 -----------ARLAPQELEQklrdylggfgfqgDKVTEETRRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLD----L 463
|
....*.
gi 1387227070 1463 QMWQAI 1468
Cdd:PRK10636 464 DMRQAL 469
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
1308-1505 |
1.86e-09 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 62.15 E-value: 1.86e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1308 VRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPPTRQAGGGFRHlGYC--PQE---DVLWPDL 1382
Cdd:TIGR02633 276 VDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYPGKFEGNVFINGKPVDIRNPAQAIRA-GIAmvPEDrkrHGIVPIL 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1383 TVREHLDLYS----AVKGLTKEEAAL-SVSRLADALKLQDQMA-LPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGM 1456
Cdd:TIGR02633 355 GVGKNITLSVlksfCFKMRIDAAAELqIIGSAIQRLKVKTASPfLPIGRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGV 434
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 1457 DPEGQLQMWQAIQAIVkssARG-ALLTTHS-MAEAEAVCDRVAIMVSGRLR 1505
Cdd:TIGR02633 435 DVGAKYEIYKLINQLA---QEGvAIIVVSSeLAEVLGLSDRVLVIGEGKLK 482
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
500-670 |
2.22e-09 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 62.14 E-value: 2.22e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 500 LQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiINMEEIRNYTGFCPQ----FNiyfDflT 575
Cdd:COG5265 374 LKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRD-VTQASLRAAIGIVPQdtvlFN---D--T 447
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 576 VRENLRlFAKIkGIPPKEVEQEVKsimmeldMHNIQDVIAK--------------ELSGGQKRKLtfGIA--ILGDPQVL 639
Cdd:COG5265 448 IAYNIA-YGRP-DASEEEVEAAAR-------AAQIHDFIESlpdgydtrvgerglKLSGGEKQRV--AIArtLLKNPPIL 516
|
170 180 190
....*....|....*....|....*....|.
gi 1387227070 640 LLDEPTAGLDPFSRHLVWNFLKERKTNHTIL 670
Cdd:COG5265 517 IFDEATSALDSRTERAIQAALREVARGRTTL 547
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1302-1507 |
2.52e-09 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 61.72 E-value: 2.52e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1302 RKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITG-DTKPTAGVVVFRDSGTP--PTRQAGGGFRHLGYCPQEDVL 1378
Cdd:PRK09700 273 SRDRKKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGvDKRAGGEIRLNGKDISPrsPLDAVKKGMAYITESRRDNGF 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1379 WPDLTVREHLDLYSAVK--------GL--TKEEAalsvsRLADalKLQDQMALPAKALPE-------GAKRKLSFALSVL 1441
Cdd:PRK09700 353 FPNFSIAQNMAISRSLKdggykgamGLfhEVDEQ-----RTAE--NQRELLALKCHSVNQnitelsgGNQQKVLISKWLC 425
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 1442 GSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSsARGALLTTHSMAEAEAVCDRVAIMVSGRLRCI 1507
Cdd:PRK09700 426 CCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADD-GKVILMVSSELPEIITVCDRIAVFCEGRLTQI 490
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
1305-1487 |
2.73e-09 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 61.87 E-value: 2.73e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSgtpptrqagggfRHLGYCPQE-DVLWPDLT 1383
Cdd:TIGR03719 335 KLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEIGET------------VKLAYVDQSrDALDPNKT 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1384 VRE-------HLDLysavkGLTKEEAALSVSRLadALKLQDQMALpAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGM 1456
Cdd:TIGR03719 403 VWEeisggldIIKL-----GKREIPSRAYVGRF--NFKGSDQQKK-VGQLSGGERNRVHLAKTLKSGGNVLLLDEPTNDL 474
|
170 180 190
....*....|....*....|....*....|....*...
gi 1387227070 1457 DPEGQLQMWQAIQ-----AIVKSSARGAL--LTTHSMA 1487
Cdd:TIGR03719 475 DVETLRALEEALLnfagcAVVISHDRWFLdrIATHILA 512
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
499-650 |
2.74e-09 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 59.62 E-value: 2.74e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 499 ALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLS-----EIINMEEIRNYtgfcpQFNIYFDF 573
Cdd:PRK11300 20 AVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEglpghQIARMGVVRTF-----QHVRLFRE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 574 LTVRENL----------RLFAKIKGIPP-KEVEQE-VKSIMMELDMHNIQDVIAKE---LSGGQKRKLTFGIAILGDPQV 638
Cdd:PRK11300 95 MTVIENLlvaqhqqlktGLFSGLLKTPAfRRAESEaLDRAATWLERVGLLEHANRQagnLAYGQQRRLEIARCMVTQPEI 174
|
170
....*....|..
gi 1387227070 639 LLLDEPTAGLDP 650
Cdd:PRK11300 175 LMLDEPAAGLNP 186
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
479-695 |
2.97e-09 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 59.83 E-value: 2.97e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 479 EAIRIRNLRKEY----------------KGKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSAT 542
Cdd:PRK13546 3 VSVNIKNVTKEYriyrtnkermkdalipKHKNKTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 543 IYNTQLSEIINMEEIRNYTGFcpqFNIYFDFLTVrenlrlfakikGIPPKEVEQEVKSIM--MELDMHNIQDViaKELSG 620
Cdd:PRK13546 83 RNGEVSVIAISAGLSGQLTGI---ENIEFKMLCM-----------GFKRKEIKAMTPKIIefSELGEFIYQPV--KKYSS 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 621 GQKRKLTFGIAILGDPQVLLLDEP-TAGLDPFSRHLVWNFLKERKTNHTILFSTQFMDEADILADRKVFLSNGKLR 695
Cdd:PRK13546 147 GMRAKLGFSINITVNPDILVIDEAlSVGDQTFAQKCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLK 222
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
494-685 |
3.07e-09 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 59.34 E-value: 3.07e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 494 PEKVEALQGICLDV-----YEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSeiinmeeirnytgFCPQFn 568
Cdd:cd03237 4 PTMKKTLGEFTLEVeggsiSESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVS-------------YKPQY- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 569 IYFDF-LTVRENLRLFAKIKGIPPkeveQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAG 647
Cdd:cd03237 70 IKADYeGTVRDLLSSITKDFYTHP----YFKTEIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAY 145
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1387227070 648 LDPFSRHLVWNFLK-----ERKT----NHTILFstqfmdeADILADR 685
Cdd:cd03237 146 LDVEQRLMASKVIRrfaenNEKTafvvEHDIIM-------IDYLADR 185
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
1309-1459 |
3.17e-09 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 61.45 E-value: 3.17e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1309 RNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTpptrqagggfrhLGYCPQ--EDVLWPDLTVRE 1386
Cdd:PRK15064 336 KNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKWSENAN------------IGYYAQdhAYDFENDLTLFD 403
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 1387 HLDLYSAVKGltKEEAALSVsrLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPE 1459
Cdd:PRK15064 404 WMSQWRQEGD--DEQAVRGT--LGRLLFSQDDIKKSVKVLSGGEKGRMLFGKLMMQKPNVLVMDEPTNHMDME 472
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
1307-1503 |
3.44e-09 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 60.20 E-value: 3.44e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKP----TAGVVVFRDSG----TPPTRQAGGGfRHLGYCPQEDVL 1378
Cdd:PRK15093 22 AVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKDnwrvTADRMRFDDIDllrlSPRERRKLVG-HNVSMIFQEPQS 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1379 WPDLTVREHLDLYSAVKGLTKEEAALSVS--RLADALKL---------QDQMALPAKALPEGAKRKLSFALSVLGSPALL 1447
Cdd:PRK15093 101 CLDPSERVGRQLMQNIPGWTYKGRWWQRFgwRKRRAIELlhrvgikdhKDAMRSFPYELTEGECQKVMIAIALANQPRLL 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 1448 LLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGR 1503
Cdd:PRK15093 181 IADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQ 236
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
503-687 |
3.47e-09 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 59.78 E-value: 3.47e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 503 ICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIIN--MEEIRNYTGFCPQFNIYFDFLTVREN- 579
Cdd:PRK11831 26 ISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRsrLYTVRKRMSMLFQSGALFTDMNVFDNv 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 580 ---LRLFAKIkgipPKEVEQEvkSIMMELD---MHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSR 653
Cdd:PRK11831 106 aypLREHTQL----PAPLLHS--TVMMKLEavgLRGAAKLMPSELSGGMARRAALARAIALEPDLIMFDEPFVGQDPITM 179
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1387227070 654 HLVWNFLKErkTNHT-----ILFS------TQFMDEADILADRKV 687
Cdd:PRK11831 180 GVLVKLISE--LNSAlgvtcVVVShdvpevLSIADHAYIVADKKI 222
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
512-694 |
3.51e-09 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 59.72 E-value: 3.51e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 512 LTAILGHSGAGKSSLLSIL-------GGWSACTE---GSATIYNTQlseiiNMEEIRNYTGFCPQFNIYFDFLTVRENLR 581
Cdd:PRK14271 49 VTSLMGPTGSGKTTFLRTLnrmndkvSGYRYSGDvllGGRSIFNYR-----DVLEFRRRVGMLFQRPNPFPMSIMDNVLA 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 582 LFAKIKGIPPKEVEQEVKSIMMELDMHN-IQDVIAK---ELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVW 657
Cdd:PRK14271 124 GVRAHKLVPRKEFRGVAQARLTEVGLWDaVKDRLSDspfRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIE 203
|
170 180 190
....*....|....*....|....*....|....*..
gi 1387227070 658 NFLKERKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:PRK14271 204 EFIRSLADRLTVIIVTHNLAQAARISDRAALFFDGRL 240
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
462-699 |
4.26e-09 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 61.53 E-value: 4.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 462 LSCDDSFEPVSPefhrkeAIRIRNLRKEYKGKPEKvEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSA 541
Cdd:PLN03232 602 LAQNPPLQPGAP------AISIKNGYFSWDSKTSK-PTLSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSHAETSS 674
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 542 TIyntqlseiinmeeIRNYTGFCPQFNIYFDfLTVRENLRLFAKIkgippkEVEQ-----EVKSIMMELDM---HNIQDV 613
Cdd:PLN03232 675 VV-------------IRGSVAYVPQVSWIFN-ATVRENILFGSDF------ESERywraiDVTALQHDLDLlpgRDLTEI 734
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 614 IAK--ELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWN--FLKERKTNHTILFSTQ--FMDeadiLADRKV 687
Cdd:PLN03232 735 GERgvNISGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVAHQVFDscMKDELKGKTRVLVTNQlhFLP----LMDRII 810
|
250
....*....|..
gi 1387227070 688 FLSNGKLRCAGS 699
Cdd:PLN03232 811 LVSEGMIKEEGT 822
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
500-649 |
4.27e-09 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 61.30 E-value: 4.27e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 500 LQGICLDVYEGQLTAILGHSGAGKSSLL-SILGGWsACTEGS-----ATIYNtqlseiINMEEIRNYTGFCPQ----FNI 569
Cdd:COG4618 348 LRGVSFSLEPGEVLGVIGPSGSGKSTLArLLVGVW-PPTAGSvrldgADLSQ------WDREELGRHIGYLPQdvelFDG 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 570 yfdflTVRENLrlfAKIKGIPPKEVEQEVKSImmelDMHniqDVIAK--------------ELSGGQKRKLTFGIAILGD 635
Cdd:COG4618 421 -----TIAENI---ARFGDADPEKVVAAAKLA----GVH---EMILRlpdgydtrigeggaRLSGGQRQRIGLARALYGD 485
|
170
....*....|....
gi 1387227070 636 PQVLLLDEPTAGLD 649
Cdd:COG4618 486 PRLVVLDEPNSNLD 499
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
1302-1504 |
5.11e-09 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 58.25 E-value: 5.11e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1302 RKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTP-PTRQAGGGFRHLGYCPQEDVLWP 1380
Cdd:cd03248 24 RPDTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLL--DGKPiSQYEHKYLHSKVSLVGQEPVLFA 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 DlTVREHLD--LYSAVKGLTKEEAALS-----VSRLADAlkLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPT 1453
Cdd:cd03248 102 R-SLQDNIAygLQSCSFECVKEAAQKAhahsfISELASG--YDTEVGEKGSQLSGGQKQRVAIARALIRNPQVLILDEAT 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 1454 TGMDPEGQLQMWQAIQAivKSSARGALLTTHSMAEAEAVcDRVAIMVSGRL 1504
Cdd:cd03248 179 SALDAESEQQVQQALYD--WPERRTVLVIAHRLSTVERA-DQILVLDGGRI 226
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
478-670 |
7.93e-09 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 60.42 E-value: 7.93e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 478 KEAIRIRNLRKEYKGKPEKveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEI 557
Cdd:PRK11176 339 KGDIEFRNVTFTYPGKEVP--ALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDY-TLASL 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 558 RNYTGFCPQfNIYFDFLTVRENLrLFAKIKGIPPKEVEQEVK-SIMMEL--DMHNIQDVIAKE----LSGGQKRKLTFGI 630
Cdd:PRK11176 416 RNQVALVSQ-NVHLFNDTIANNI-AYARTEQYSREQIEEAARmAYAMDFinKMDNGLDTVIGEngvlLSGGQRQRIAIAR 493
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1387227070 631 AILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTIL 670
Cdd:PRK11176 494 ALLRDSPILILDEATSALDTESERAIQAALDELQKNRTSL 533
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
494-649 |
8.00e-09 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 60.05 E-value: 8.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 494 PEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRNYTGFCPQFNIYFDF 573
Cdd:TIGR01842 328 GGKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQW-DRETFGKHIGYLPQDVELFPG 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 574 lTVRENLRLF------------AKIKGippkeVEQEVKSIMMELDMhniqdVIAKE---LSGGQKRKLTFGIAILGDPQV 638
Cdd:TIGR01842 407 -TVAENIARFgenadpekiieaAKLAG-----VHELILRLPDGYDT-----VIGPGgatLSGGQRQRIALARALYGDPKL 475
|
170
....*....|.
gi 1387227070 639 LLLDEPTAGLD 649
Cdd:TIGR01842 476 VVLDEPNSNLD 486
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
1304-1511 |
8.06e-09 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 58.17 E-value: 8.06e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1304 TKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF--RDSGTPPTRQ-AgggfRHLGYCPQEDVLWP 1380
Cdd:COG4604 13 GKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVdgLDVATTPSRElA----KRLAILRQENHINS 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 DLTVREhldL-------YSavKG-LTKEEAALsVSRLADALKLQD--------------QMALPAKALPEGAKrklsfal 1438
Cdd:COG4604 89 RLTVRE---LvafgrfpYS--KGrLTAEDREI-IDEAIAYLDLEDladryldelsggqrQRAFIAMVLAQDTD------- 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 1439 svlgspaLLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQ 1511
Cdd:COG4604 156 -------YVLLDEPLNNLDMKHSVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPE 221
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
1279-1504 |
9.10e-09 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 58.25 E-value: 9.10e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1279 EPVIMASCLHKEYKQEKkrcfsarktktAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMIT--GDTKP---TAGVVVFRD 1353
Cdd:PRK14239 3 EPILQVSDLSVYYNKKK-----------ALNSVSLDFYPNEITALIGPSGSGKSTLLRSINrmNDLNPevtITGSIVYNG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1354 SGTPPTRQAGGGFR-HLGYCPQEDVLWPdLTVREHLDLYSAVKGLTKE-------EAALSVSRLADALKlqDQMALPAKA 1425
Cdd:PRK14239 72 HNIYSPRTDTVDLRkEIGMVFQQPNPFP-MSIYENVVYGLRLKGIKDKqvldeavEKSLKGASIWDEVK--DRLHDSALG 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 1426 LPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSArgALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:PRK14239 149 LSGGQQQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDDYT--MLLVTRSMQQASRISDRTGFFLDGDL 225
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
1309-1484 |
1.19e-08 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 59.87 E-value: 1.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1309 RNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGvVVFRdsgTPPTRQAGGGFRHLgycpqeDVLwpDLTVREHL 1388
Cdd:PLN03073 526 KNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSG-TVFR---SAKVRMAVFSQHHV------DGL--DLSSNPLL 593
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1389 DLYSAVKGLTKEE--AALSVSRLADALKLQdqmalPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEgqlqmwq 1466
Cdd:PLN03073 594 YMMRCFPGVPEQKlrAHLGSFGVTGNLALQ-----PMYTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDLD------- 661
|
170 180
....*....|....*....|.
gi 1387227070 1467 AIQAIVKSSAR---GALLTTH 1484
Cdd:PLN03073 662 AVEALIQGLVLfqgGVLMVSH 682
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
1322-1459 |
1.71e-08 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 58.98 E-value: 1.71e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1322 GLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDsgtpptrqaggGFRhLGYCPQEDVLWPDLTVREH-----------LDL 1390
Cdd:PRK11819 37 GVLGLNGAGKSTLLRIMAGVDKEFEGEARPAP-----------GIK-VGYLPQEPQLDPEKTVRENveegvaevkaaLDR 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1391 YSAVKGLTKEEAALSvsrlaDAL-----KLQDQ--------------MALPAKALPE----------GAKRKLSFALSVL 1441
Cdd:PRK11819 105 FNEIYAAYAEPDADF-----DALaaeqgELQEIidaadawdldsqleIAMDALRCPPwdakvtklsgGERRRVALCRLLL 179
|
170
....*....|....*...
gi 1387227070 1442 GSPALLLLDEPTTGMDPE 1459
Cdd:PRK11819 180 EKPDMLLLDEPTNHLDAE 197
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
481-649 |
1.77e-08 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 58.93 E-value: 1.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKS----SLLSILGGWSACTEGSATiYNTQlsEIINMEE 556
Cdd:COG4172 7 LSVEDLSVAFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSIL-FDGQ--DLLGLSE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 557 -----IR---------------NytgfcPQFNIYFDfltVRENLRLfakIKGIPPKEVEQEVKSImmeLDMHNIQDVIAK 616
Cdd:COG4172 84 relrrIRgnriamifqepmtslN-----PLHTIGKQ---IAEVLRL---HRGLSGAAARARALEL---LERVGIPDPERR 149
|
170 180 190
....*....|....*....|....*....|....*....
gi 1387227070 617 ------ELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLD 649
Cdd:COG4172 150 ldayphQLSGGQRQRVMIAMALANEPDLLIADEPTTALD 188
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
493-662 |
1.90e-08 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 58.18 E-value: 1.90e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 493 KPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEI--INMEEIRNYTGFcpqfnIY 570
Cdd:PRK15079 30 PPKTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMkdDEWRAVRSDIQM-----IF 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 571 FDFLT-----------VRENLRLFAKikGIPPKEVEQEVKSIMMELDMhnIQDVIAK---ELSGGQKRKLtfGIA---IL 633
Cdd:PRK15079 105 QDPLAslnprmtigeiIAEPLRTYHP--KLSRQEVKDRVKAMMLKVGL--LPNLINRyphEFSGGQCQRI--GIAralIL 178
|
170 180
....*....|....*....|....*....
gi 1387227070 634 gDPQVLLLDEPTAGLDPFSRHLVWNFLKE 662
Cdd:PRK15079 179 -EPKLIICDEPVSALDVSIQAQVVNLLQQ 206
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
509-694 |
2.11e-08 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 58.81 E-value: 2.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 509 EGQLTAILGHSGAGKSSLLSILGGWSACTEGSaTIYNTQLSeIINMEE--IRNYTGfcpqfNIyFDFLT-----VRENLR 581
Cdd:PRK11147 28 DNERVCLVGRNGAGKSTLMKILNGEVLLDDGR-IIYEQDLI-VARLQQdpPRNVEG-----TV-YDFVAegieeQAEYLK 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 582 LFAKIKgippKEVEQEVKSIMME--------LDMHN-------IQDVIAK----------ELSGGQKRKLTFGIAILGDP 636
Cdd:PRK11147 100 RYHDIS----HLVETDPSEKNLNelaklqeqLDHHNlwqlenrINEVLAQlgldpdaalsSLSGGWLRKAALGRALVSNP 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 637 QVLLLDEPTAGLDPFSRHLVWNFLKERKTnhTILFSTQfmDEADI--LADRKVFLSNGKL 694
Cdd:PRK11147 176 DVLLLDEPTNHLDIETIEWLEGFLKTFQG--SIIFISH--DRSFIrnMATRIVDLDRGKL 231
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
510-693 |
2.36e-08 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 59.35 E-value: 2.36e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 510 GQLTAILGHSGAGKSSLLSILGGwsaCTEGSATIYNTQLS-EIINMEEIRN-YTG---FCPQFNIYFDFLTVRENLRLFA 584
Cdd:TIGR00956 87 GELTVVLGRPGSGCSTLLKTIAS---NTDGFHIGVEGVITyDGITPEEIKKhYRGdvvYNAETDVHFPHLTVGETLDFAA 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 585 KIKGIP--PKEV-EQEVKSIMMELDM------H----NIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPF 651
Cdd:TIGR00956 164 RCKTPQnrPDGVsREEYAKHIADVYMatyglsHtrntKVGNDFVRGVSGGERKRVSIAEASLGGAKIQCWDNATRGLDSA 243
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1387227070 652 SrhlVWNFLKERKTNHTILFSTQFM------DEADILADRKVFLSNGK 693
Cdd:TIGR00956 244 T---ALEFIRALKTSANILDTTPLVaiyqcsQDAYELFDKVIVLYEGY 288
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
1308-1508 |
2.40e-08 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 56.77 E-value: 2.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1308 VRNVSFCINKGEVLGLLGHNGAGKSTCIKM------ITGDTKPTAGVVVFRDSGTPPTRQAGGGFRHLGYCPQEDVLWPD 1381
Cdd:PRK14267 20 IKGVDLKIPQNGVFALMGPSGCGKSTLLRTfnrlleLNEEARVEGEVRLFGRNIYSPDVDPIEVRREVGMVFQYPNPFPH 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 LTVREHLDLYSAVKGLTKE--------EAALSVSRLADALKlqDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPT 1453
Cdd:PRK14267 100 LTIYDNVAIGVKLNGLVKSkkeldervEWALKKAALWDEVK--DRLNDYPSNLSGGQRQRLVIARALAMKPKILLMDEPT 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 1454 TGMDPEGQLQMWQAIQAIVKSSArgALLTTHSMAEAEAVCDRVAIMVSGRLRCIG 1508
Cdd:PRK14267 178 ANIDPVGTAKIEELLFELKKEYT--IVLVTHSPAQAARVSDYVAFLYLGKLIEVG 230
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
1297-1503 |
2.73e-08 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 58.40 E-value: 2.73e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1297 RCFSARKtktAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGdTKPTA---GVVVFrdSGTP-------PTRQAGGGF 1366
Cdd:PRK13549 13 KTFGGVK---ALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSG-VYPHGtyeGEIIF--EGEElqasnirDTERAGIAI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1367 RHlgycpQEDVLWPDLTVREHLDL---------------YSAVKGLTKE-----EAALSVSRLADAlklQDQMALPAKAL 1426
Cdd:PRK13549 87 IH-----QELALVKELSVLENIFLgneitpggimdydamYLRAQKLLAQlkldiNPATPVGNLGLG---QQQLVEIAKAL 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 1427 PEGAKrklsfalsvlgspaLLLLDEPTTGMDpEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGR 1503
Cdd:PRK13549 159 NKQAR--------------LLILDEPTASLT-ESETAVLLDIIRDLKAHGIACIYISHKLNEVKAISDTICVIRDGR 220
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
500-649 |
3.73e-08 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 56.28 E-value: 3.73e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 500 LQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSatiyntqlseIINMEEIRnyTGFCPQfNIYFDF---LTV 576
Cdd:PRK09544 20 LSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGV----------IKRNGKLR--IGYVPQ-KLYLDTtlpLTV 86
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 577 RENLRLFAKIKG--IPP--KEVEQEvksimmeldmHNIQDVIAKeLSGGQKRKLTFGIAILGDPQVLLLDEPTAGLD 649
Cdd:PRK09544 87 NRFLRLRPGTKKedILPalKRVQAG----------HLIDAPMQK-LSGGETQRVLLARALLNRPQLLVLDEPTQGVD 152
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
1307-1518 |
3.75e-08 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 57.91 E-value: 3.75e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTRQAGGGFRH-LGYCPQEDVLWPDlTVR 1385
Cdd:PRK11160 355 VLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILL--NGQPIADYSEAALRQaISVVSQRVHLFSA-TLR 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1386 EHLDLysAVKGLTKEEaalsvsrLADALK-------LQDQMALPA------KALPEGAKRKLSFALSVLGSPALLLLDEP 1452
Cdd:PRK11160 432 DNLLL--AAPNASDEA-------LIEVLQqvgleklLEDDKGLNAwlgeggRQLSGGEQRRLGIARALLHDAPLLLLDEP 502
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 1453 TTGMDPEGQLQMWQAIQAIVKSsaRGALLTTHSMAEAEAVcDRVAIMVSGRLRCIGSVQHLKSKFG 1518
Cdd:PRK11160 503 TEGLDAETERQILELLAEHAQN--KTVLMITHRLTGLEQF-DRICVMDNGQIIEQGTHQELLAQQG 565
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
1305-1510 |
3.86e-08 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 55.23 E-value: 3.86e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITG--DTKPTAGVVVFRDsgtpptrqagggfrhlgycpqEDVLwpDL 1382
Cdd:cd03217 13 KEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGhpKYEVTEGEILFKG---------------------EDIT--DL 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1383 TVREHldlysAVKGLT---KEEAALSVSRLADALklqdqmalpaKALPEG-----AKRKLSFALSVLGsPALLLLDEPTT 1454
Cdd:cd03217 70 PPEER-----ARLGIFlafQYPPEIPGVKNADFL----------RYVNEGfsggeKKRNEILQLLLLE-PDLAILDEPDS 133
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 1455 GMDPEGQLQMWQAIQAIvKSSARGALLTTHSMAEAEAV-CDRVAIMVSGRLRCIGSV 1510
Cdd:cd03217 134 GLDIDALRLVAEVINKL-REEGKSVLIITHYQRLLDYIkPDRVHVLYDGRIVKSGDK 189
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
483-662 |
4.08e-08 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 58.02 E-value: 4.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 483 IRNLRKEYkgkPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATiyntqLSEIINMeeirnytG 562
Cdd:TIGR03719 7 MNRVSKVV---PPKKEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEAR-----PQPGIKV-------G 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 563 FCPQFNIYFDFLTVRENLRL-FAKIKGI-------------PPKEVEQ------EVKSIMMELDMHNIQ----------- 611
Cdd:TIGR03719 72 YLPQEPQLDPTKTVRENVEEgVAEIKDAldrfneisakyaePDADFDKlaaeqaELQEIIDAADAWDLDsqleiamdalr 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 612 ----DVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE 662
Cdd:TIGR03719 152 cppwDADVTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAESVAWLERHLQE 206
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
498-699 |
4.52e-08 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 56.17 E-value: 4.52e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 498 EALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGW------SACTEGSATIYNTQlseiiNMEEIRNYTGFC---PQFN 568
Cdd:PRK13638 15 PVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLlrpqkgAVLWQGKPLDYSKR-----GLLALRQQVATVfqdPEQQ 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 569 IYFDflTVRENLRLFAKIKGIPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGL 648
Cdd:PRK13638 90 IFYT--DIDSDIAFSLRNLGVPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGL 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 649 DPFSRHLVWNFLKE--RKTNHTILfSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:PRK13638 168 DPAGRTQMIAIIRRivAQGNHVII-SSHDIDLIYEISDAVYVLRQGQILTHGA 219
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
480-649 |
5.49e-08 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 58.21 E-value: 5.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKGKPEKvEALQGICLDVYEGQLTAILGHSGAGKSSLLS-ILGGWSACTEGSATiyntqlseiinmeeIR 558
Cdd:PLN03130 614 AISIKNGYFSWDSKAER-PTLSNINLDVPVGSLVAIVGSTGEGKTSLISaMLGELPPRSDASVV--------------IR 678
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 559 NYTGFCPQFNIYFDfLTVRENLrLFakikGIP--PKEVEQ--EVKSIMMELDM---HNIQDVIAK--ELSGGQKRKLTFG 629
Cdd:PLN03130 679 GTVAYVPQVSWIFN-ATVRDNI-LF----GSPfdPERYERaiDVTALQHDLDLlpgGDLTEIGERgvNISGGQKQRVSMA 752
|
170 180
....*....|....*....|
gi 1387227070 630 IAILGDPQVLLLDEPTAGLD 649
Cdd:PLN03130 753 RAVYSNSDVYIFDDPLSALD 772
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
500-699 |
5.96e-08 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 58.03 E-value: 5.96e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 500 LQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATiyntqlseiinmeeIRNYTGFCPQfNIYFDFLTVREN 579
Cdd:TIGR00957 654 LNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVH--------------MKGSVAYVPQ-QAWIQNDSLREN 718
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 580 LrLFAkiKGIPPKEVEQEVKSIMMELDMHNI----QDVIAKE---LSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDP-F 651
Cdd:TIGR00957 719 I-LFG--KALNEKYYQQVLEACALLPDLEILpsgdRTEIGEKgvnLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAhV 795
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 652 SRHLVWNF-----LKERKTNHTILFSTQFMDEADILadrkVFLSNGKLRCAGS 699
Cdd:TIGR00957 796 GKHIFEHVigpegVLKNKTRILVTHGISYLPQVDVI----IVMSGGKISEMGS 844
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
497-698 |
6.10e-08 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 56.77 E-value: 6.10e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 497 VEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLsEIINMEEIRNYTGFCPQ-FNIYFDFlT 575
Cdd:PRK09536 16 TTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDV-EALSARAASRRVASVPQdTSLSFEF-D 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 576 VRENLRL-----FAKIKGIPPKEvEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLD- 649
Cdd:PRK09536 94 VRQVVEMgrtphRSRFDTWTETD-RAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLLLDEPTASLDi 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 650 -------PFSRHLVwnflkerKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAG 698
Cdd:PRK09536 173 nhqvrtlELVRRLV-------DDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAG 221
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
1311-1512 |
6.41e-08 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 57.23 E-value: 6.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1311 VSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrDSGTPPTRQAGGGFRH-LGYCPQ---EDVLWPDLTVRE 1386
Cdd:PRK11288 272 ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYL-DGKPIDIRSPRDAIRAgIMLCPEdrkAEGIIPVHSVAD 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1387 HLDLYSAVKGLT-------KEEAALSVSRLAdALKL------QDQMALPA----KALpegAKRKLSFALSVlgspalLLL 1449
Cdd:PRK11288 351 NINISARRHHLRagclinnRWEAENADRFIR-SLNIktpsreQLIMNLSGgnqqKAI---LGRWLSEDMKV------ILL 420
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 1450 DEPTTGMDPEGQLQMWQAIQAIVKsSARGALLTTHSMAEAEAVCDRVAIMVSGRLRciGSVQH 1512
Cdd:PRK11288 421 DEPTRGIDVGAKHEIYNVIYELAA-QGVAVLFVSSDLPEVLGVADRIVVMREGRIA--GELAR 480
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
1311-1509 |
6.92e-08 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 55.58 E-value: 6.92e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1311 VSFCINKGEVLGLLGHNGAGKST---CIKMITgdtKPTAGVVVFRDSGTPPTRQAGGGFR------------HLGYCPQE 1375
Cdd:COG4598 27 VSLTARKGDVISIIGSSGSGKSTflrCINLLE---TPDSGEIRVGGEEIRLKPDRDGELVpadrrqlqrirtRLGMVFQS 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1376 DVLWPDLTVRE-------HldlysaVKGLTKEEAalsvsrLADALKLQDQMALPAKA------LPEGAKRKLSFALSVLG 1442
Cdd:COG4598 104 FNLWSHMTVLEnvieapvH------VLGRPKAEA------IERAEALLAKVGLADKRdaypahLSGGQQQRAAIARALAM 171
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1443 SPALLLLDEPTTGMDPEgqlqMWQAIQAIVKSSA---RGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGS 1509
Cdd:COG4598 172 EPEVMLFDEPTSALDPE----LVGEVLKVMRDLAeegRTMLVVTHEMGFARDVSSHVVFLHQGRIEEQGP 237
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
467-695 |
7.60e-08 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 57.14 E-value: 7.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 467 SFEPVSPEFHRKEAIRIRNLRKEYKGKPeKVEALQGICLDVYEGQLTAILGHSGAGKSSLLS-ILGGWSACTEGSATIYN 545
Cdd:TIGR02633 244 SLYPHEPHEIGDVILEARNLTCWDVINP-HRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQaLFGAYPGKFEGNVFING 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 546 TQL----------SEIINMEEIRNYTGFCPQfniyfdfLTVRENLRL-----FAKIKGIPPKEVEQEVKSIMMELDMHNI 610
Cdd:TIGR02633 323 KPVdirnpaqairAGIAMVPEDRKRHGIVPI-------LGVGKNITLsvlksFCFKMRIDAAAELQIIGSAIQRLKVKTA 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 611 Q-DVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQfMDEADILADRKV 687
Cdd:TIGR02633 396 SpFLPIGRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQlaQEGVAIIVVSSE-LAEVLGLSDRVL 474
|
....*...
gi 1387227070 688 FLSNGKLR 695
Cdd:TIGR02633 475 VIGEGKLK 482
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
1307-1504 |
8.55e-08 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 55.52 E-value: 8.55e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPTRQAGGGFRHLGYCPQ--EDVLWpD 1381
Cdd:PRK13649 22 ALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDtliTSTSKNKDIKQIRKKVGLVFQfpESQLF-E 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 LTVREHLDLYSAVKGLTKEEA-ALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEG 1460
Cdd:PRK13649 101 ETVLKDVAFGPQNFGVSQEEAeALAREKLALVGISESLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAGLDPKG 180
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1387227070 1461 QLQMWQAIQAIVKSSARgALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:PRK13649 181 RKELMTLFKKLHQSGMT-IVLVTHLMDDVANYADFVYVLEKGKL 223
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
500-649 |
9.40e-08 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 55.18 E-value: 9.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 500 LQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINMEEIRNyTGFCPQFNIYFDFLTVREN 579
Cdd:PRK10575 27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARK-VAYLPQQLPAAEGMTVREL 105
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 580 LRL--------FAKIKGIPPKEVEQEVKSIMMELDMHNIQDviakELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLD 649
Cdd:PRK10575 106 VAIgrypwhgaLGRFGAADREKVEEAISLVGLKPLAHRLVD----SLSGGERQRAWIAMLVAQDSRCLLLDEPTSALD 179
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
505-692 |
1.00e-07 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 54.58 E-value: 1.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 505 LDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIyntqlsEIINMEEIRNYTGfcpqfniyfdfltvrenlrlfa 584
Cdd:COG2401 51 LEIEPGEIVLIVGASGSGKSTLLRLLAGALKGTPVAGCV------DVPDNQFGREASL---------------------- 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 585 kIKGIPPKeveQEVKSIMMELDMHNIQDVIA-----KELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDP-FSRHLVWN 658
Cdd:COG2401 103 -IDAIGRK---GDFKDAVELLNAVGLSDAVLwlrrfKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRqTAKRVARN 178
|
170 180 190
....*....|....*....|....*....|....*.
gi 1387227070 659 FLKE-RKTNHTILFSTQFMD-EADILADRKVFLSNG 692
Cdd:COG2401 179 LQKLaRRAGITLVVATHHYDvIDDLQPDLLIFVGYG 214
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
1301-1503 |
1.03e-07 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 56.64 E-value: 1.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1301 ARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTcikmitgdtkpTAgVVVFRDSGTPPTRQAGGGFRHLGycpqEDVLWP 1380
Cdd:PRK15134 18 QQTVRTVVNDVSLQIEAGETLALVGESGSGKSV-----------TA-LSILRLLPSPPVVYPSGDIRFHG----ESLLHA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 D-LTVR-----------------------------EHLDLYsavKGLTKEEAALSVSRLAD-------ALKLQDqmaLPA 1423
Cdd:PRK15134 82 SeQTLRgvrgnkiamifqepmvslnplhtlekqlyEVLSLH---RGMRREAARGEILNCLDrvgirqaAKRLTD---YPH 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1424 KaLPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGR 1503
Cdd:PRK15134 156 Q-LSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGR 234
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
501-649 |
1.10e-07 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 54.04 E-value: 1.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 501 QGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGsatiyntqlsEII-NMEEIRNYtgfCPQFN---IYF----- 571
Cdd:PRK13538 18 SGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAG----------EVLwQGEPIRRQ---RDEYHqdlLYLghqpg 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 572 --DFLTVRENLRLFAKIKGippkEVEQEvkSIMMELDMHNIQ---DVIAKELSGGQKRKltfgIAI----LGDPQVLLLD 642
Cdd:PRK13538 85 ikTELTALENLRFYQRLHG----PGDDE--ALWEALAQVGLAgfeDVPVRQLSAGQQRR----VALarlwLTRAPLWILD 154
|
....*..
gi 1387227070 643 EPTAGLD 649
Cdd:PRK13538 155 EPFTAID 161
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
1307-1516 |
1.13e-07 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 55.68 E-value: 1.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKP----TAGVVVFRD----SGTPPTRQAGGGfRHLGYCPQEDV- 1377
Cdd:COG4170 22 AVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKDnwhvTADRFRWNGidllKLSPRERRKIIG-REIAMIFQEPSs 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1378 -LWPDLTVREHLdlysavkgltkEEAALSVS-----------RLADALKL---------QDQMALPAKALPEGAKRKLSF 1436
Cdd:COG4170 101 cLDPSAKIGDQL-----------IEAIPSWTfkgkwwqrfkwRKKRAIELlhrvgikdhKDIMNSYPHELTEGECQKVMI 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1437 ALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLKSK 1516
Cdd:COG4170 170 AMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYCGQTVESGPTEQILKS 249
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
1315-1498 |
1.25e-07 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 53.34 E-value: 1.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1315 INKGEVLGLLGHNGAGKSTCIKMITGDTKPTagvvvfrdsgtpptrqagggfrhlgycpQEDVLWPDLTVrehldlysAV 1394
Cdd:cd03222 22 VKEGEVIGIVGPNGTGKTTAVKILAGQLIPN----------------------------GDNDEWDGITP--------VY 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1395 KgltkeeaalsvsrladalklqdqmalPAK-ALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVK 1473
Cdd:cd03222 66 K--------------------------PQYiDLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSE 119
|
170 180
....*....|....*....|....*
gi 1387227070 1474 SSARGALLTTHSMAEAEAVCDRVAI 1498
Cdd:cd03222 120 EGKKTALVVEHDLAVLDYLSDRIHV 144
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
1305-1515 |
1.42e-07 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 54.72 E-value: 1.42e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGvvvFRDSGTP--------PTRQAGGGFRHLGYCPQED 1376
Cdd:PRK14271 34 KTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSG---YRYSGDVllggrsifNYRDVLEFRRRVGMLFQRP 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1377 VLWPDLTVREHLDLYSAVKGLTKEE------AALSVSRLADALKlqDQMALPAKALPEGAKRKLSFALSVLGSPALLLLD 1450
Cdd:PRK14271 111 NPFPMSIMDNVLAGVRAHKLVPRKEfrgvaqARLTEVGLWDAVK--DRLSDSPFRLSGGQQQLLCLARTLAVNPEVLLLD 188
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 1451 EPTTGMDPEGQLQMWQAIQAIVKSSArgALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLKS 1515
Cdd:PRK14271 189 EPTSALDPTTTEKIEEFIRSLADRLT--VIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFS 251
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
478-649 |
1.78e-07 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 55.74 E-value: 1.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 478 KEAIRIRNLRKEYKGKPEkveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEI 557
Cdd:PRK13657 332 KGAVEFDDVSFSYDNSRQ---GVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTV-TRASL 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 558 RNYTGFCPQFNIYFDfLTVRENLRLfakikGIP---PKEVEQEVKS------IMMELDMHniqDVIAKE----LSGGQKR 624
Cdd:PRK13657 408 RRNIAVVFQDAGLFN-RSIEDNIRV-----GRPdatDEEMRAAAERaqahdfIERKPDGY---DTVVGErgrqLSGGERQ 478
|
170 180
....*....|....*....|....*
gi 1387227070 625 KLTFGIAILGDPQVLLLDEPTAGLD 649
Cdd:PRK13657 479 RLAIARALLKDPPILILDEATSALD 503
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
1305-1509 |
1.79e-07 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 54.28 E-value: 1.79e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITG-----DTKPTA-------GVVVFRDSGTPPTRQAGGGFRHLGYC 1372
Cdd:PRK14246 23 KAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRlieiyDSKIKVdgkvlyfGKDIFQIDAIKLRKEVGMVFQQPNPF 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1373 PQ----EDVLWPdltVREH-LDLYSAVKGLTKEeaalSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALL 1447
Cdd:PRK14246 103 PHlsiyDNIAYP---LKSHgIKEKREIKKIVEE----CLRKVGLWKEVYDRLNSPASQLSGGQQQRLTIARALALKPKVL 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 1448 LLDEPTTGMDPEGQLQMWQAIQAIVKSSArgALLTTHSMAEAEAVCDRVAIMVSGRLRCIGS 1509
Cdd:PRK14246 176 LMDEPTSMIDIVNSQAIEKLITELKNEIA--IVIVSHNPQQVARVADYVAFLYNGELVEWGS 235
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
1306-1504 |
1.84e-07 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 54.71 E-value: 1.84e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1306 TAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVV--VFRDSGT-----------------PPT------- 1359
Cdd:PRK13651 21 KALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIewIFKDEKNkkktkekekvleklviqKTRfkkikki 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1360 ----RQAGGGFRHLGYCPQEDVLWPDLtvrehldLYSAVK-GLTKEEAAlsvSRLADALKLqdqMALPAKALPE------ 1428
Cdd:PRK13651 101 keirRRVGVVFQFAEYQLFEQTIEKDI-------IFGPVSmGVSKEEAK---KRAAKYIEL---VGLDESYLQRspfels 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 1429 -GAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKsSARGALLTTHSMAEAEAVCDRVAIMVSGRL 1504
Cdd:PRK13651 168 gGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNK-QGKTIILVTHDLDNVLEWTKRTIFFKDGKI 243
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
481-672 |
1.93e-07 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 54.48 E-value: 1.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEKVeaLQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSAcTEGSATI----YNTqlseiINMEE 556
Cdd:cd03289 3 MTVKDLTAKYTEGGNAV--LENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-TEGDIQIdgvsWNS-----VPLQK 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 557 IRNYTGFCPQFNIYFDFlTVRENLRLFAKIKGIPPKEVEQEV--KSIMMEL-DMHNIQDVIAK-ELSGGQKRKLTFGIAI 632
Cdd:cd03289 75 WRKAFGVIPQKVFIFSG-TFRKNLDPYGKWSDEEIWKVAEEVglKSVIEQFpGQLDFVLVDGGcVLSHGHKQLMCLARSV 153
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1387227070 633 LGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTILFS 672
Cdd:cd03289 154 LSKAKILLLDEPSAHLDPITYQVIRKTLKQAFADCTVILS 193
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
1306-1554 |
2.93e-07 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 53.70 E-value: 2.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1306 TAVRNVSFCINKGEVLGLLGHNGAGKSTC----IKMITGDTKPTAGVVVFRDSGTPPTRQAgggfrhLGYCPQEDVLWPD 1381
Cdd:cd03289 18 AVLENISFSISPGQRVGLLGRTGSGKSTLlsafLRLLNTEGDIQIDGVSWNSVPLQKWRKA------FGVIPQKVFIFSG 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 lTVREHLDLYsavkGLTKEEAALSVSRLADALKLQDQmaLPAK----------ALPEGAKRKLSFALSVLGSPALLLLDE 1451
Cdd:cd03289 92 -TFRKNLDPY----GKWSDEEIWKVAEEVGLKSVIEQ--FPGQldfvlvdggcVLSHGHKQLMCLARSVLSKAKILLLDE 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1452 PTTGMDPegqlQMWQAIQAIVKSSARGA--LLTTHSMaEAEAVCDRVAIMVSGRLRCIGSVQHLKSKfgKDYLLEvkvkA 1529
Cdd:cd03289 165 PSAHLDP----ITYQVIRKTLKQAFADCtvILSEHRI-EAMLECQRFLVIEENKVRQYDSIQKLLNE--KSHFKQ----A 233
|
250 260
....*....|....*....|....*
gi 1387227070 1530 LTlveplHMEILKLFPQAARQERYS 1554
Cdd:cd03289 234 IS-----PSDRLKLFPRRNSSKSKR 253
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
1303-1513 |
3.20e-07 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 55.08 E-value: 3.20e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1303 KTKTAVRNVSFCINKGEVLGLLGHNGAGKS----TCIKMITGDTKPTAGVVVFRD----SGTPPTRQAGGGfRHLGYCPQ 1374
Cdd:COG4172 21 GTVEAVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSILFDGqdllGLSERELRRIRG-NRIAMIFQ 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1375 EDV--LWPDLTV----REHLDLYsavKGLTKEEAalsvsrLADALKLQDQMALPAkalpegAKRKL-SF----------- 1436
Cdd:COG4172 100 EPMtsLNPLHTIgkqiAEVLRLH---RGLSGAAA------RARALELLERVGIPD------PERRLdAYphqlsggqrqr 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1437 ---ALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHL 1513
Cdd:COG4172 165 vmiAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQGPTAEL 244
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
481-666 |
3.20e-07 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 55.42 E-value: 3.20e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPEkVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINMEEIRNY 560
Cdd:PTZ00265 383 IQFKNVRFHYDTRKD-VEIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIINDSHNLKDINLKWWRSK 461
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQ----------FNIYFDFLTVRE-------------------NLRLFAKIKGIPP-----------------KEV 594
Cdd:PTZ00265 462 IGVVSQdpllfsnsikNNIKYSLYSLKDlealsnyynedgndsqenkNKRNSCRAKCAGDlndmsnttdsneliemrKNY 541
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 595 E----QEVKSIMMELDMHNIQDVI-----------AKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNF 659
Cdd:PTZ00265 542 QtikdSEVVDVSKKVLIHDFVSALpdkyetlvgsnASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKT 621
|
....*..
gi 1387227070 660 LKERKTN 666
Cdd:PTZ00265 622 INNLKGN 628
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
493-694 |
3.59e-07 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 55.37 E-value: 3.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 493 KPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiINMEEIRNYTGFCPQFNIYFD 572
Cdd:PLN03232 1245 RPGLPPVLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAK-FGLTDLRRVLSIIPQSPVLFS 1323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 573 FlTVRENLRLFAkikgippkevEQEVKSIMMELDMHNIQDVIAK--------------ELSGGQKRKLTFGIAILGDPQV 638
Cdd:PLN03232 1324 G-TVRFNIDPFS----------EHNDADLWEALERAHIKDVIDRnpfgldaevseggeNFSVGQRQLLSLARALLRRSKI 1392
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 639 LLLDEPTAGLDPFSRHLVWNFLKERKTNHTILFSTQFMDEAdILADRKVFLSNGKL 694
Cdd:PLN03232 1393 LVLDEATASVDVRTDSLIQRTIREEFKSCTMLVIAHRLNTI-IDCDKILVLSSGQV 1447
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
481-700 |
4.25e-07 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 53.25 E-value: 4.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKP-----EKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQL------- 548
Cdd:PRK15112 5 LEVRNLSKTFRYRTgwfrrQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLhfgdysy 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 549 -SEIINMEEIRNYTGFCPQFNI--YFDFltvreNLRLFAKIKGIP-PKEVEQEVKSIMMELDMHNiqdVIAKELSGGQKR 624
Cdd:PRK15112 85 rSQRIRMIFQDPSTSLNPRQRIsqILDF-----PLRLNTDLEPEQrEKQIIETLRQVGLLPDHAS---YYPHMLAPGQKQ 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 625 KLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKERKTNHTI--LFSTQFMDEADILADRKVFLSNGKLRCAGSS 700
Cdd:PRK15112 157 RLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGIsyIYVTQHLGMMKHISDQVLVMHQGEVVERGST 234
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
497-648 |
4.58e-07 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 54.62 E-value: 4.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 497 VEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGwsactegsatIYNTQLSEIINMEEIRNYTG-------------- 562
Cdd:PRK10762 17 VKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTG----------IYTRDAGSILYLGKEVTFNGpkssqeagigiihq 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 563 ---FCPQfniyfdfLTVRENL---RLFAKIKG-IPPKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGD 635
Cdd:PRK10762 87 elnLIPQ-------LTIAENIflgREFVNRFGrIDWKKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFE 159
|
170
....*....|...
gi 1387227070 636 PQVLLLDEPTAGL 648
Cdd:PRK10762 160 SKVIIMDEPTDAL 172
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
1302-1353 |
4.66e-07 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 53.25 E-value: 4.66e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 1302 RKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD 1353
Cdd:PRK15112 23 RQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDD 74
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
455-694 |
4.91e-07 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 54.41 E-value: 4.91e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 455 GNEMNSELScddSFEPVSPEFHRKEAIRIRNLRKEYKGKpekveaLQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWS 534
Cdd:PRK09700 243 GRELQNRFN---AMKENVSNLAHETVFEVRNVTSRDRKK------VRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVD 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 535 ACTEGSATIYNTQLSE----------IINMEEIRNYTGFCPQFNIyfdfltvRENLRLFAKIK--------GIPPKEVEQ 596
Cdd:PRK09700 314 KRAGGEIRLNGKDISPrspldavkkgMAYITESRRDNGFFPNFSI-------AQNMAISRSLKdggykgamGLFHEVDEQ 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 597 ---EVKSIMMELDMHNIQDVIAkELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFS 672
Cdd:PRK09700 387 rtaENQRELLALKCHSVNQNIT-ELSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQlADDGKVILMV 465
|
250 260
....*....|....*....|..
gi 1387227070 673 TQFMDEADILADRKVFLSNGKL 694
Cdd:PRK09700 466 SSELPEIITVCDRIAVFCEGRL 487
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
465-649 |
4.95e-07 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 54.25 E-value: 4.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 465 DDSFEPVSPEFhRKEAIRIRNLRKEykgkpekvEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIY 544
Cdd:COG1129 242 EDLFPKRAAAP-GEVVLEVEGLSVG--------GVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLD 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 545 NTQLSeiinmeeIRNYT-------GFCPQfniyfD------FL--TVREN-----LRLFAKIKGIPPKEVEQEVKSIMME 604
Cdd:COG1129 313 GKPVR-------IRSPRdairagiAYVPE-----DrkgeglVLdlSIRENitlasLDRLSRGGLLDRRRERALAEEYIKR 380
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1387227070 605 LD--MHNIQDVIaKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLD 649
Cdd:COG1129 381 LRikTPSPEQPV-GNLSGGNQQKVVLAKWLATDPKVLILDEPTRGID 426
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
1310-1515 |
5.00e-07 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 53.23 E-value: 5.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1310 NVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPP-TR--------------QAGGGFRHLGYCpq 1374
Cdd:PRK11831 25 NISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAmSRsrlytvrkrmsmlfQSGALFTDMNVF-- 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1375 EDVLWPdltVREHLDL-----YSAVkgLTKEEAAlsvsRLADALKLqdqmaLPAKaLPEGAKRKLSFALSVLGSPALLLL 1449
Cdd:PRK11831 103 DNVAYP---LREHTQLpapllHSTV--MMKLEAV----GLRGAAKL-----MPSE-LSGGMARRAALARAIALEPDLIMF 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 1450 DEPTTGMDPegqLQMWQAIQAIVK-SSARGA--LLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLKS 1515
Cdd:PRK11831 168 DEPFVGQDP---ITMGVLVKLISElNSALGVtcVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQALQA 233
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
483-649 |
5.27e-07 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 52.72 E-value: 5.27e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 483 IRNLRKEYKGKpekvEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSA--CTEGSATIYNtqlSEIINME-EIRN 559
Cdd:CHL00131 10 IKNLHASVNEN----EILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGHPAykILEGDILFKG---ESILDLEpEERA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YTGFCPQF----------NIyfDFLTVRENLRLfaKIKGIPPKEVEQEVKSIMMELDMHNIQDV-----IAKELSGGQKR 624
Cdd:CHL00131 83 HLGIFLAFqypieipgvsNA--DFLRLAYNSKR--KFQGLPELDPLEFLEIINEKLKLVGMDPSflsrnVNEGFSGGEKK 158
|
170 180
....*....|....*....|....*
gi 1387227070 625 KLTFGIAILGDPQVLLLDEPTAGLD 649
Cdd:CHL00131 159 RNEILQMALLDSELAILDETDSGLD 183
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
1380-1513 |
5.79e-07 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 52.61 E-value: 5.79e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1380 PDLTVREHLDLYSAVKGLTKEEAALSvSRLADALK-------LQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEP 1452
Cdd:PRK14247 95 PNLSIFENVALGLKLNRLVKSKKELQ-ERVRWALEkaqlwdeVKDRLDAPAGKLSGGQQQRLCIARALAFQPEVLLADEP 173
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 1453 TTGMDPEGQLQMWQAIQAIVKSSArgALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHL 1513
Cdd:PRK14247 174 TANLDPENTAKIESLFLELKKDMT--IVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREV 232
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
1308-1457 |
5.98e-07 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 52.94 E-value: 5.98e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1308 VRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVvfRDSGtpptrqagggfrHLGYCPQEDVLWPDlTVREH 1387
Cdd:cd03291 53 LKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKI--KHSG------------RISFSSQFSWIMPG-TIKEN 117
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 1388 L------DLY---SAVKGLTKEEaalSVSRLADalKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMD 1457
Cdd:cd03291 118 IifgvsyDEYrykSVVKACQLEE---DITKFPE--KDNTVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLD 191
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
481-699 |
6.16e-07 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 51.76 E-value: 6.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKpekvEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSA--CTEGSATIYNTQLSEiINMEEI- 557
Cdd:cd03217 1 LEIKDLHVSVGGK----EILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPKyeVTEGEILFKGEDITD-LPPEERa 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 558 RNYTGFCPQFNIYFDFLTVRENLRlfakikgippkeveqevksimmELDMhniqdviakELSGGQKRKLTFGIAILGDPQ 637
Cdd:cd03217 76 RLGIFLAFQYPPEIPGVKNADFLR----------------------YVNE---------GFSGGEKKRNEILQLLLLEPD 124
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1387227070 638 VLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEAD-ILADRKVFLSNGKLRCAGS 699
Cdd:cd03217 125 LAILDEPDSGLDIDALRLVAEVINKlREEGKSVLIITHYQRLLDyIKPDRVHVLYDGRIVKSGD 188
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
496-649 |
6.40e-07 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 53.85 E-value: 6.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 496 KVEALQG-----ICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSE----------IINMEEIRNY 560
Cdd:PRK10762 259 KVDNLSGpgvndVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTrspqdglangIVYISEDRKR 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 561 TGFCPQfniyfdfLTVREN-----LRLFAKIKGIPPKEVEQEVKSIMMELdmHNI----QDVIAKELSGGQKRKLTFGIA 631
Cdd:PRK10762 339 DGLVLG-------MSVKENmsltaLRYFSRAGGSLKHADEQQAVSDFIRL--FNIktpsMEQAIGLLSGGNQQKVAIARG 409
|
170
....*....|....*...
gi 1387227070 632 ILGDPQVLLLDEPTAGLD 649
Cdd:PRK10762 410 LMTRPKVLILDEPTRGVD 427
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
501-699 |
7.27e-07 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 52.68 E-value: 7.27e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 501 QGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINMEEIRNyTGFCPQFNIYFDFLTVRE-- 578
Cdd:PRK10253 24 ENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARR-IGLLAQNATTPGDITVQElv 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 579 ------NLRLFAKIKgippKEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFS 652
Cdd:PRK10253 103 argrypHQPLFTRWR----KEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWLDISH 178
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1387227070 653 RHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGKLRCAGS 699
Cdd:PRK10253 179 QIDLLELLSElnREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGA 227
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
1308-1457 |
8.16e-07 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 54.15 E-value: 8.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1308 VRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVvfRDSGtpptrqagggfrHLGYCPQEDVLWPDlTVREH 1387
Cdd:TIGR01271 442 LKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKI--KHSG------------RISFSPQTSWIMPG-TIKDN 506
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1388 LdlysaVKGLTKEEaaLSVSRLADALKLQDQMA-LPAK----------ALPEGAKRKLSFALSVLGSPALLLLDEPTTGM 1456
Cdd:TIGR01271 507 I-----IFGLSYDE--YRYTSVIKACQLEEDIAlFPEKdktvlgeggiTLSGGQRARISLARAVYKDADLYLLDSPFTHL 579
|
.
gi 1387227070 1457 D 1457
Cdd:TIGR01271 580 D 580
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
470-699 |
8.94e-07 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 53.71 E-value: 8.94e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 470 PVSPEFHRKEAIRIRNLRKEYKGKPEKVEALQGICLDVYEGQLTAILGHSGAGKS----SLLSIL---GGWSACTEGSAT 542
Cdd:PRK10261 2 PHSDELDARDVLAVENLNIAFMQEQQKIAAVRNLSFSLQRGETLAIVGESGSGKSvtalALMRLLeqaGGLVQCDKMLLR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 543 IYNTQLSEI-----INMEEIRN----------YTGFCPQFNIYFDfltVRENLRLFakiKGIPPKEVEQEVKSIMMELDM 607
Cdd:PRK10261 82 RRSRQVIELseqsaAQMRHVRGadmamifqepMTSLNPVFTVGEQ---IAESIRLH---QGASREEAMVEAKRMLDQVRI 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 608 HNIQDVIAK---ELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLK--ERKTNHTILFSTQFMDEADIL 682
Cdd:PRK10261 156 PEAQTILSRyphQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKvlQKEMSMGVIFITHDMGVVAEI 235
|
250
....*....|....*..
gi 1387227070 683 ADRKVFLSNGKLRCAGS 699
Cdd:PRK10261 236 ADRVLVMYQGEAVETGS 252
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
493-649 |
1.05e-06 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 53.64 E-value: 1.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 493 KPEKVEA-------LQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGsatiyNTQLSEIINMeeirnytGFCP 565
Cdd:PRK10636 314 KMEKVSAgygdriiLDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSG-----EIGLAKGIKL-------GYFA 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 566 QFNIyfDFLTVREN-LRLFAKIKgipPKEVEQEVKSIMMELDMHNIQDV-IAKELSGGQKRKLTFGIAILGDPQVLLLDE 643
Cdd:PRK10636 382 QHQL--EFLRADESpLQHLARLA---PQELEQKLRDYLGGFGFQGDKVTeETRRFSGGEKARLVLALIVWQRPNLLLLDE 456
|
....*.
gi 1387227070 644 PTAGLD 649
Cdd:PRK10636 457 PTNHLD 462
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
1305-1459 |
1.11e-06 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 53.42 E-value: 1.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVvfrdsgtpptrqagggfrHLG------YCPQ-EDV 1377
Cdd:PRK11147 332 KQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRI------------------HCGtklevaYFDQhRAE 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1378 LWPDLTVREHLdlysavkGLTKEEAALS-VSR-----LADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDE 1451
Cdd:PRK11147 394 LDPEKTVMDNL-------AEGKQEVMVNgRPRhvlgyLQDFLFHPKRAMTPVKALSGGERNRLLLARLFLKPSNLLILDE 466
|
....*...
gi 1387227070 1452 PTTGMDPE 1459
Cdd:PRK11147 467 PTNDLDVE 474
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
481-687 |
1.44e-06 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 51.61 E-value: 1.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYK-----GKPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiINME 555
Cdd:PRK10419 4 LNVSGLSHHYAhgglsGKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAK-LNRA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 556 EIRNYTG------------FCPQFNIYFdflTVRENLRLFAKIkgippKEVEQEVKSI----MMELDMhNIQDVIAKELS 619
Cdd:PRK10419 83 QRKAFRRdiqmvfqdsisaVNPRKTVRE---IIREPLRHLLSL-----DKAERLARASemlrAVDLDD-SVLDKRPPQLS 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 620 GGQKRKLTFGIAILGDPQVLLLDEPTAGLDpfsRHL---VWNFLKE--RKTNHTILFSTQ-------------FMDEADI 681
Cdd:PRK10419 154 GGQLQRVCLARALAVEPKLLILDEAVSNLD---LVLqagVIRLLKKlqQQFGTACLFITHdlrlverfcqrvmVMDNGQI 230
|
....*.
gi 1387227070 682 LADRKV 687
Cdd:PRK10419 231 VETQPV 236
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
1304-1505 |
1.81e-06 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 51.19 E-value: 1.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1304 TKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMIT------GDTKPTAGVVVFRDSGTPPTRQAGGGFRHLGYCPQEDV 1377
Cdd:PRK14258 19 TQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNrmneleSEVRVEGRVEFFNQNIYERRVNLNRLRRQVSMVHPKPN 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1378 LWPdLTVREHLDLYSAVKGLTKE-------EAALSVSRLADALKlqDQMALPAKALPEGAKRKLSFALSVLGSPALLLLD 1450
Cdd:PRK14258 99 LFP-MSVYDNVAYGVKIVGWRPKleiddivESALKDADLWDEIK--HKIHKSALDLSGGQQQRLCIARALAVKPKVLLMD 175
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 1451 EPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLR 1505
Cdd:PRK14258 176 EPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGNENR 230
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
500-680 |
1.91e-06 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 50.79 E-value: 1.91e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 500 LQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGsATIYNTQLSEIINMEEIRNYTGFCPQFNIYFDFL---TV 576
Cdd:cd03290 17 LSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEG-KVHWSNKNESEPSFEATRSRNRYSVAYAAQKPWLlnaTV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 577 RENLRLFAKIKGIPPKEVeQEVKSIMMELDM--HNIQDVIAKE---LSGGQKRKLTFGIAILGDPQVLLLDEPTAGLD-P 650
Cdd:cd03290 96 EENITFGSPFNKQRYKAV-TDACSLQPDIDLlpFGDQTEIGERginLSGGQRQRICVARALYQNTNIVFLDDPFSALDiH 174
|
170 180 190
....*....|....*....|....*....|....*..
gi 1387227070 651 FSRHL----VWNFLKERKtnHTILFST---QFMDEAD 680
Cdd:cd03290 175 LSDHLmqegILKFLQDDK--RTLVLVThklQYLPHAD 209
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
462-649 |
1.95e-06 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 52.38 E-value: 1.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 462 LSCDDSFEPVSPEFHRKEAIRIRNLRKEYKGK-------PEKVEALQGICLDVYEGQLTAILGHSGAGKSSL-LSILGGW 533
Cdd:COG4172 257 LAAEPRGDPRPVPPDAPPLLEARDLKVWFPIKrglfrrtVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLgLALLRLI 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 534 SacTEGSATIYNTQLSEiINMEEIRNYtgfCPQFNIYF-D-F------LTVR----ENLRLFAkiKGIPPKEVEQEVKSI 601
Cdd:COG4172 337 P--SEGEIRFDGQDLDG-LSRRALRPL---RRRMQVVFqDpFgslsprMTVGqiiaEGLRVHG--PGLSAAERRARVAEA 408
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 602 MME--LDmhniQDVIAK---ELSGGQKRKLtfGIA---ILgDPQVLLLDEPTAGLD 649
Cdd:COG4172 409 LEEvgLD----PAARHRyphEFSGGQRQRI--AIAralIL-EPKLLVLDEPTSALD 457
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
505-665 |
2.25e-06 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 49.46 E-value: 2.25e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 505 LDVYEGQLTAILGHSGAGKSSLLSILGG-WSActeGSATIYNTQLSEIInmeeirnytgFCPQfNIYFDFLTVRENLrlf 583
Cdd:cd03223 22 FEIKPGDRLLITGPSGTGKSSLFRALAGlWPW---GSGRIGMPEGEDLL----------FLPQ-RPYLPLGTLREQL--- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 584 akikgIPPKEveqevksimmeldmhniqdviaKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKER 663
Cdd:cd03223 85 -----IYPWD----------------------DVLSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESEDRLYQLLKEL 137
|
..
gi 1387227070 664 KT 665
Cdd:cd03223 138 GI 139
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
500-670 |
2.44e-06 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 52.12 E-value: 2.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 500 LQGICLDVYEGQLTAILGHSGAGKSSLL-SILGGWSActeGSATIYNTQLSEIInmeeirnytgFCPQfNIYFDFLTVRE 578
Cdd:COG4178 379 LEDLSLSLKPGERLLITGPSGSGKSTLLrAIAGLWPY---GSGRIARPAGARVL----------FLPQ-RPYLPLGTLRE 444
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 579 NLrlfakikgIPPKEVEQ----EVKSImmeLDMHNIQDVI---------AKELSGGQKRKLTFGIAILGDPQVLLLDEPT 645
Cdd:COG4178 445 AL--------LYPATAEAfsdaELREA---LEAVGLGHLAerldeeadwDQVLSLGEQQRLAFARLLLHKPDWLFLDEAT 513
|
170 180
....*....|....*....|....*
gi 1387227070 646 AGLDPFSRHLVWNFLKERKTNHTIL 670
Cdd:COG4178 514 SALDEENEAALYQLLREELPGTTVI 538
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
468-685 |
2.49e-06 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 52.09 E-value: 2.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 468 FE--PVSPEFHRKEAIRIRNLRKEYKGKPEKVEAlqGiclDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSatiyn 545
Cdd:COG1245 327 FEvhAPRREKEEETLVEYPDLTKSYGGFSLEVEG--G---EIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGE----- 396
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 546 tqlseiINMEEIRNYTgfcPQFnIYFDF-LTVRENLRLFAKiKGIPPKEVEQEvksIMMELDMHNIQDVIAKELSGGQKR 624
Cdd:COG1245 397 ------VDEDLKISYK---PQY-ISPDYdGTVEEFLRSANT-DDFGSSYYKTE---IIKPLGLEKLLDKNVKDLSGGELQ 462
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 625 KLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLK----ERKT-----NHTILFstqfmdeADILADR 685
Cdd:COG1245 463 RVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRrfaeNRGKtamvvDHDIYL-------IDYISDR 525
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
510-694 |
2.94e-06 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 52.54 E-value: 2.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 510 GQLTAILGHSGAGKSSLLSILGGW---SACTEGSATIYNTQLSEIINmeeiRNYTGFCPQFNIYFDFLTVRENLRLFAKI 586
Cdd:PLN03140 191 SRMTLLLGPPSSGKTTLLLALAGKldpSLKVSGEITYNGYRLNEFVP----RKTSAYISQNDVHVGVMTVKETLDFSARC 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 587 KGI--------------------PPKEVEQEVKSIMME----------------LDMHN---IQDVIAKELSGGQKRKLT 627
Cdd:PLN03140 267 QGVgtrydllselarrekdagifPEAEVDLFMKATAMEgvksslitdytlkilgLDICKdtiVGDEMIRGISGGQKKRVT 346
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 628 FGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFS-TQFMDEADILADRKVFLSNGKL 694
Cdd:PLN03140 347 TGEMIVGPTKTLFMDEISTGLDSSTTYQIVKCLQQivHLTEATVLMSlLQPAPETFDLFDDIILLSEGQI 416
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
1307-1508 |
3.08e-06 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 51.78 E-value: 3.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF--RDSGTPPTRQAGGGFRHLGYCPQEDV--LWPDL 1382
Cdd:PRK10261 339 AVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFngQRIDTLSPGKLQALRRDIQFIFQDPYasLDPRQ 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1383 TV----REHLDLYSAVKGltkEEAALSVSRLADALKLQDQMALP-AKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMD 1457
Cdd:PRK10261 419 TVgdsiMEPLRVHGLLPG---KAAAARVAWLLERVGLLPEHAWRyPHEFSGGQRQRICIARALALNPKVIIADEAVSALD 495
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 1458 PEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIG 1508
Cdd:PRK10261 496 VSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
1279-1503 |
3.26e-06 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 51.61 E-value: 3.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1279 EPVIMASCLHKEYKQEKKRCFSARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTkPTAGVVVFRdsGTPP 1358
Cdd:COG4172 273 PPLLEARDLKVWFPIKRGLFRRTVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLI-PSEGEIRFD--GQDL 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1359 TRQAGGGFRHLgycpQEDV----------LWPDLTVR----EHLDLYSavKGLTKEEaalsvsRLADALKLQDQMALPAK 1424
Cdd:COG4172 350 DGLSRRALRPL----RRRMqvvfqdpfgsLSPRMTVGqiiaEGLRVHG--PGLSAAE------RRARVAEALEEVGLDPA 417
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1425 AL---P-E--GAKRK---LSFALsVLgSPALLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDR 1495
Cdd:COG4172 418 ARhryPhEfsGGQRQriaIARAL-IL-EPKLLVLDEPTSALDVSVQAQILDLLRDLQREHGLAYLFISHDLAVVRALAHR 495
|
....*...
gi 1387227070 1496 VAIMVSGR 1503
Cdd:COG4172 496 VMVMKDGK 503
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
1308-1505 |
3.50e-06 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 51.47 E-value: 3.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1308 VRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDsGTPPT----RQAgggFRH-LGYCPQE---DVLW 1379
Cdd:PRK13549 278 VDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGAYPGRWEGEIFID-GKPVKirnpQQA---IAQgIAMVPEDrkrDGIV 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1380 PDLTVREHLDLySAVKGLTKeeaalsVSRLADALKL---QDQMA----------LPAKALPEGAKRKLSFALSVLGSPAL 1446
Cdd:PRK13549 354 PVMGVGKNITL-AALDRFTG------GSRIDDAAELktiLESIQrlkvktaspeLAIARLSGGNQQKAVLAKCLLLNPKI 426
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 1447 LLLDEPTTGMDPEGQLQMWQAIQAIVKssaRG-ALLTTHS-MAEAEAVCDRVAIMVSGRLR 1505
Cdd:PRK13549 427 LILDEPTRGIDVGAKYEIYKLINQLVQ---QGvAIIVISSeLPEVLGLSDRVLVMHEGKLK 484
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
482-649 |
3.60e-06 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 50.31 E-value: 3.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 482 RIRNLRKEYKGkpekVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSAtIYNT---QLSEIINMEE-- 556
Cdd:PRK11701 8 SVRGLTKLYGP----RKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEV-HYRMrdgQLRDLYALSEae 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 557 ----IRNYTGFCPQF-------------NIYFDFLTVREnlRLFAKIKGIPPKEVEQevksimMELDMHNIQDViAKELS 619
Cdd:PRK11701 83 rrrlLRTEWGFVHQHprdglrmqvsaggNIGERLMAVGA--RHYGDIRATAGDWLER------VEIDAARIDDL-PTTFS 153
|
170 180 190
....*....|....*....|....*....|
gi 1387227070 620 GGQKRKLTFGIAILGDPQVLLLDEPTAGLD 649
Cdd:PRK11701 154 GGMQQRLQIARNLVTHPRLVFMDEPTGGLD 183
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
485-694 |
4.11e-06 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 51.21 E-value: 4.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 485 NLRKEYKGKPE-KVEALQG-----ICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSE-------- 550
Cdd:PRK15439 258 NRRQQAAGAPVlTVEDLTGegfrnISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINAlstaqrla 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 551 --IINMEEIRNYTGFCPQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQEVKSIMMELdmhNIQDVIAKELSGGQKRKLTF 628
Cdd:PRK15439 338 rgLVYLPEDRQSSGLYLDAPLAWNVCALTHNRRGFWIKPARENAVLERYRRALNIKF---NHAEQAARTLSGGNQQKVLI 414
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 629 GIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:PRK15439 415 AKCLEASPQLLIVDEPTRGVDVSARNDIYQLIRSiAAQNVAVLFISSDLEEIEQMADRVLVMHQGEI 481
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
1307-1507 |
4.43e-06 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 51.27 E-value: 4.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD---SGTPPTRQAGGGF-------RHLGYCPQED 1376
Cdd:PRK10982 263 SIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGkkiNNHNANEAINHGFalvteerRSTGIYAYLD 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1377 VLWPDLTvrEHLDLYSAVKGLTKEEAALSVSR-LADALKLQD-QMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTT 1454
Cdd:PRK10982 343 IGFNSLI--SNIRNYKNKVGLLDNSRMKSDTQwVIDSMRVKTpGHRTQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTR 420
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 1455 GMDPEGQLQMWQAIQAIVKSSaRGALLTTHSMAEAEAVCDRVAIMVSGRLRCI 1507
Cdd:PRK10982 421 GIDVGAKFEIYQLIAELAKKD-KGIIIISSEMPELLGITDRILVMSNGLVAGI 472
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
499-694 |
4.91e-06 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 51.27 E-value: 4.91e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 499 ALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIY-----NTQLSEIIN-----MEEIRNYTGFCPQFN 568
Cdd:PRK10982 263 SIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHgkkinNHNANEAINhgfalVTEERRSTGIYAYLD 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 569 IYFDFLTvrENLRLF-AKIKGIPPKEVEQEVKSIM--MELDMHNIQDVIAkELSGGQKRKLTFGIAILGDPQVLLLDEPT 645
Cdd:PRK10982 343 IGFNSLI--SNIRNYkNKVGLLDNSRMKSDTQWVIdsMRVKTPGHRTQIG-SLSGGNQQKVIIGRWLLTQPEILMLDEPT 419
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 646 AGLDPFSRHLVWNFLKE--RKTNHTILFSTQfMDEADILADRKVFLSNGKL 694
Cdd:PRK10982 420 RGIDVGAKFEIYQLIAElaKKDKGIIIISSE-MPELLGITDRILVMSNGLV 469
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
467-649 |
5.08e-06 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 51.35 E-value: 5.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 467 SFE--PVSPEFHRKEAIRIRNLRKEYKGKPEKVEALQgicldVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSatiy 544
Cdd:PRK13409 325 EFEerPPRDESERETLVEYPDLTKKLGDFSLEVEGGE-----IYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGE---- 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 545 ntqlseiINMEEIRNYTgfcPQFnIYFDF-LTVRENLRLFAKIKGIPPKEVEqevksIMMELDMHNIQDVIAKELSGGQK 623
Cdd:PRK13409 396 -------VDPELKISYK---PQY-IKPDYdGTVEDLLRSITDDLGSSYYKSE-----IIKPLQLERLLDKNVKDLSGGEL 459
|
170 180
....*....|....*....|....*.
gi 1387227070 624 RKLTFGIAILGDPQVLLLDEPTAGLD 649
Cdd:PRK13409 460 QRVAIAACLSRDADLYLLDEPSAHLD 485
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
510-650 |
5.19e-06 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 49.08 E-value: 5.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 510 GQLTAILGHSGAGKSSLLSILGGWSACTEGSATIyNTQLSEIINMEEIRNYTGFCPQFNIYFDFLtvrENLRLFAKIKGI 589
Cdd:PRK13543 37 GEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQI-DGKTATRGDRSRFMAYLGHLPGLKADLSTL---ENLHFLCGLHGR 112
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1387227070 590 PPKEVEQEVKSImmeLDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDP 650
Cdd:PRK13543 113 RAKQMPGSALAI---VGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDL 170
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
481-648 |
6.13e-06 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 50.98 E-value: 6.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGkpekVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIY----NTQLSEIINMEE 556
Cdd:TIGR02633 2 LEMKGIVKTFGG----VKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGTWDGEIYwsgsPLKASNIRDTER 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 557 -----IRNYTGFCPQfniyfdfLTVRENLRLFAKI--KG--IPPKEVEQEVKSIMMELDMHNIQDV-IAKELSGGQKRKL 626
Cdd:TIGR02633 78 agiviIHQELTLVPE-------LSVAENIFLGNEItlPGgrMAYNAMYLRAKNLLRELQLDADNVTrPVGDYGGGQQQLV 150
|
170 180
....*....|....*....|..
gi 1387227070 627 TFGIAILGDPQVLLLDEPTAGL 648
Cdd:TIGR02633 151 EIAKALNKQARLLILDEPSSSL 172
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
481-660 |
6.92e-06 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 50.78 E-value: 6.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 481 IRIRNLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGG-----WS------ACTEGSA-TIYNTQ- 547
Cdd:PRK10938 261 IVLNNGVVSYNDRP----ILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGdhpqgYSndltlfGRRRGSGeTIWDIKk 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 548 ----LSEIINME-----EIRN--YTGFCPQFNIYfdfLTVRENLRLFAkikgippkeveqevksiMMELDMHNIQDVIAK 616
Cdd:PRK10938 337 higyVSSSLHLDyrvstSVRNviLSGFFDSIGIY---QAVSDRQQKLA-----------------QQWLDILGIDKRTAD 396
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1387227070 617 ----ELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFL 660
Cdd:PRK10938 397 apfhSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLVRRFV 444
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
480-649 |
7.29e-06 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 50.87 E-value: 7.29e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEY-KGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiINMEEIR 558
Cdd:PRK10790 340 RIDIDNVSFAYrDDNL----VLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSS-LSHSVLR 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 559 NYTGFCPQfniyfDFLTVRENlrLFAKI---KGIPPKEVEQEVKSIMMELDMHNIQDVI-------AKELSGGQKRKLTF 628
Cdd:PRK10790 415 QGVAMVQQ-----DPVVLADT--FLANVtlgRDISEEQVWQALETVQLAELARSLPDGLytplgeqGNNLSVGQKQLLAL 487
|
170 180
....*....|....*....|.
gi 1387227070 629 GIAILGDPQVLLLDEPTAGLD 649
Cdd:PRK10790 488 ARVLVQTPQILILDEATANID 508
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
1304-1503 |
7.98e-06 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 48.62 E-value: 7.98e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1304 TKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSgtpptrqagggfrhLGYCPQEDVLWPDlT 1383
Cdd:cd03250 17 TSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS--------------IAYVSQEPWIQNG-T 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1384 VREHLdlysaVKGLTKEEAalsvsRLADALK----LQDQMALPAKALPE----------GAKRKLSFALSVLGSPALLLL 1449
Cdd:cd03250 82 IRENI-----LFGKPFDEE-----RYEKVIKacalEPDLEILPDGDLTEigekginlsgGQKQRISLARAVYSDADIYLL 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 1450 DEPTTGMDPE-GQLQMWQAIQ-AIVKSSARgaLLTTHSMAEAEAvCDRVAIMVSGR 1503
Cdd:cd03250 152 DDPLSAVDAHvGRHIFENCILgLLLNNKTR--ILVTHQLQLLPH-ADQIVVLDNGR 204
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
1310-1459 |
8.65e-06 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 50.50 E-value: 8.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1310 NVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSgtpptrqagggfRHLGYCPQE-DVLWPDLTVREhl 1388
Cdd:PRK11819 342 DLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKIGET------------VKLAYVDQSrDALDPNKTVWE-- 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1389 dlysavkgltkeeaalSVSRLADALKL------------------QDQMAlPAKALPEGAKRKLSFALSVLGSPALLLLD 1450
Cdd:PRK11819 408 ----------------EISGGLDIIKVgnreipsrayvgrfnfkgGDQQK-KVGVLSGGERNRLHLAKTLKQGGNVLLLD 470
|
....*....
gi 1387227070 1451 EPTTGMDPE 1459
Cdd:PRK11819 471 EPTNDLDVE 479
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
500-692 |
1.02e-05 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 49.08 E-value: 1.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 500 LQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATiYNTQLSeiinmeeirnytgFCPQFNiYFDFLTVREN 579
Cdd:cd03291 53 LKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIK-HSGRIS-------------FSSQFS-WIMPGTIKEN 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 580 LrlfakIKGIPPKEVEQE--VKSIMMELDMHNIQD----VIAK---ELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDP 650
Cdd:cd03291 118 I-----IFGVSYDEYRYKsvVKACQLEEDITKFPEkdntVLGEggiTLSGGQRARISLARAVYKDADLYLLDSPFGYLDV 192
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1387227070 651 FSRHLVW-NFLKERKTNHTILFSTQFMDEADIlADRKVFLSNG 692
Cdd:cd03291 193 FTEKEIFeSCVCKLMANKTRILVTSKMEHLKK-ADKILILHEG 234
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
1296-1457 |
1.07e-05 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 50.11 E-value: 1.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1296 KRCFSARKTKTAV-RNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGV--VVFRDSGTPPTRQAGGGFR-HLGY 1371
Cdd:PRK10535 11 RRSYPSGEEQVEVlKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTyrVAGQDVATLDADALAQLRReHFGF 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1372 CPQEDVLWPDLTVREHLDLYSAVKGLTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDE 1451
Cdd:PRK10535 91 IFQRYHLLSHLTAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADE 170
|
....*.
gi 1387227070 1452 PTTGMD 1457
Cdd:PRK10535 171 PTGALD 176
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
1305-1521 |
1.27e-05 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 49.70 E-value: 1.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTC----IKMItgdtkPTAGVVVFrdSGTPP---TRQAGGGFRHLGYCPQED- 1376
Cdd:PRK15134 299 NVVVKNISFTLRPGETLGLVGESGSGKSTTglalLRLI-----NSQGEIWF--DGQPLhnlNRRQLLPVRHRIQVVFQDp 371
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1377 --VLWPDLTVREHLDlysavKGLTKEEAALSVS-RLADALKLQDQMAL--------PAkALPEGAKRKLSFALSVLGSPA 1445
Cdd:PRK15134 372 nsSLNPRLNVLQIIE-----EGLRVHQPTLSAAqREQQVIAVMEEVGLdpetrhryPA-EFSGGQRQRIAIARALILKPS 445
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1387227070 1446 LLLLDEPTTGMDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSVQHLKSKFGKDY 1521
Cdd:PRK15134 446 LIILDEPTSSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERVFAAPQQEY 521
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
1279-1347 |
1.34e-05 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 49.19 E-value: 1.34e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 1279 EPVIMASCLHKEYkQEKKRCFSARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAG 1347
Cdd:PRK11308 3 QPLLQAIDLKKHY-PVKRGLFKPERLVKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGG 70
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
1307-1497 |
1.49e-05 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 48.62 E-value: 1.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1307 AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMI--TGDTKPTA---GVVVFR-----DSGTPPTRQAgggfRHLGYCPQED 1376
Cdd:PRK14243 25 AVKNVWLDIPKNQITAFIGPSGCGKSTILRCFnrLNDLIPGFrveGKVTFHgknlyAPDVDPVEVR----RRIGMVFQKP 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1377 VLWPDlTVREHLDLYSAVKGLTKE-----EAALSVSRLADALKlqDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDE 1451
Cdd:PRK14243 101 NPFPK-SIYDNIAYGARINGYKGDmdelvERSLRQAALWDEVK--DKLKQSGLSLSGGQQQRLCIARAIAVQPEVILMDE 177
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1387227070 1452 PTTGMDPEGQLQMWQAIQAIVKSSArgALLTTHSMAEAEAVCDRVA 1497
Cdd:PRK14243 178 PCSALDPISTLRIEELMHELKEQYT--IIIVTHNMQQAARVSDMTA 221
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
1305-1489 |
1.80e-05 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 48.44 E-value: 1.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1305 KTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdSGTPPTRQAGGGF-RHLGYCPQEDVLWPDLT 1383
Cdd:PRK10253 20 YTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWL--DGEHIQHYASKEVaRRIGLLAQNATTPGDIT 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1384 VRE--------HLDLYSAVKgltKEEAAlSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTG 1455
Cdd:PRK10253 98 VQElvargrypHQPLFTRWR---KEDEE-AVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTW 173
|
170 180 190
....*....|....*....|....*....|....
gi 1387227070 1456 MDPEGQLQMWQAIQAIVKSSARGALLTTHSMAEA 1489
Cdd:PRK10253 174 LDISHQIDLLELLSELNREKGYTLAAVLHDLNQA 207
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
1325-1485 |
1.86e-05 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 47.17 E-value: 1.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1325 GHNGAGKSTCIKMITGDTKPTAGVVVFRDSGTPPTRQAgggfrHLGYCPQEDVLWPDLTVREHLDLYSAVKgltkeEAAL 1404
Cdd:PRK13541 33 GANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNIAKP-----YCTYIGHNLGLKLEMTVFENLKFWSEIY-----NSAE 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1405 SVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMWQAIqaIVKSSARG-ALLTT 1483
Cdd:PRK13541 103 TLYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENRDLLNNLI--VMKANSGGiVLLSS 180
|
..
gi 1387227070 1484 HS 1485
Cdd:PRK13541 181 HL 182
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
455-656 |
1.98e-05 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 49.64 E-value: 1.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 455 GNEMNSELScddsFEPVSPEFHRKE--------AIRIRNlRKEYKGKPE------------KVEALQGICLDVYEGQLTA 514
Cdd:PTZ00265 1124 GDSENAKLS----FEKYYPLIIRKSnidvrdngGIRIKN-KNDIKGKIEimdvnfryisrpNVPIYKDLTFSCDSKKTTA 1198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 515 ILGHSGAGKSSLLSIL-----------------------------------------GGWSACTEGS----ATIYNTQlS 549
Cdd:PTZ00265 1199 IVGETGSGKSTVMSLLmrfydlkndhhivfknehtndmtneqdyqgdeeqnvgmknvNEFSLTKEGGsgedSTVFKNS-G 1277
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 550 EII---------NMEEIRNYTGFCPQFNIYFDfLTVRENLRlFAKiKGIPPKEVEQEVKSIMMEL---DMHNIQDV---- 613
Cdd:PTZ00265 1278 KILldgvdicdyNLKDLRNLFSIVSQEPMLFN-MSIYENIK-FGK-EDATREDVKRACKFAAIDEfieSLPNKYDTnvgp 1354
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 1387227070 614 IAKELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLV 656
Cdd:PTZ00265 1355 YGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLI 1397
|
|
| AAA_21 |
pfam13304 |
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ... |
592-674 |
1.98e-05 |
|
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.
Pssm-ID: 433102 [Multi-domain] Cd Length: 303 Bit Score: 48.54 E-value: 1.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 592 KEVEQEVKSIMMELDMHNIQDVIAKELSGGQKRKLTFGIAILGDPQ---VLLLDEPTAGLDPFSRHLVWNFLKE-RKTNH 667
Cdd:pfam13304 211 LVDDRLRERGLILLENGGGGELPAFELSDGTKRLLALLAALLSALPkggLLLIDEPESGLHPKLLRRLLELLKElSRNGA 290
|
....*..
gi 1387227070 668 TILFSTQ 674
Cdd:pfam13304 291 QLILTTH 297
|
|
| ABC2_membrane_3 |
pfam12698 |
ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter ... |
1037-1219 |
2.33e-05 |
|
ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter family pfam01061.
Pssm-ID: 463674 [Multi-domain] Cd Length: 345 Bit Score: 48.54 E-value: 2.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1037 YIGMSSVSDYKQKAQSQLRISGLCPSAYWCGQALVDIPFYF-GILVSIHLMYYIFLESTivlQFMFALVVCVASCAAClI 1115
Cdd:pfam12698 178 IIAVSIVEEKESRIKERLLVSGVSPLQYWLGKILGDFLVGLlQLLIILLLLFGIGIPFG---NLGLLLLLFLLYGLAY-I 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1116 LLTYVISFLFPSGRKNNGFWSLSFFLISLFMLILLGLTHSENIIIICIILIPSCTSVFFLVQMIELSSMYHrrsesqdpe 1195
Cdd:pfam12698 254 ALGYLLGSLFKNSEDAQSIIGIVILLLSGFFGGLFPLEDPPSFLQWIFSIIPFFSPIDGLLRLIYGDSLWE--------- 324
|
170 180
....*....|....*....|....
gi 1387227070 1196 ksatgkMILPIFIPYLQIIVFLFI 1219
Cdd:pfam12698 325 ------IAPSLIILLLFAVVLLLL 342
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
496-694 |
3.79e-05 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 48.37 E-value: 3.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 496 KVEALQG------ICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIINMEEIRNYTGFCPQ--- 566
Cdd:PRK11288 259 RLDGLKGpglrepISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPRDAIRAGIMLCPEdrk 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 567 FNIYFDFLTVRENL-----RLFAKIKGI--PPKEVEQEVKSI-MMELDMHNIQDVIaKELSGGQKRKltfgiAILG---- 634
Cdd:PRK11288 339 AEGIIPVHSVADNInisarRHHLRAGCLinNRWEAENADRFIrSLNIKTPSREQLI-MNLSGGNQQK-----AILGrwls 412
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 635 -DPQVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQFMDEADILADRKVFLSNGKL 694
Cdd:PRK11288 413 eDMKVILLDEPTRGIDVGAKHEIYNVIYElAAQGVAVLFVSSDLPEVLGVADRIVVMREGRI 474
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
500-714 |
8.82e-05 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 47.63 E-value: 8.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 500 LQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIiNMEEIRNYTGFCPQFNIYFDFlTVREN 579
Cdd:TIGR00957 1302 LRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKI-GLHDLRFKITIIPQDPVLFSG-SLRMN 1379
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 580 LRLFAKIKgippkevEQEVksiMMELDMHNIQDVIA--------------KELSGGQKRKLTFGIAILGDPQVLLLDEPT 645
Cdd:TIGR00957 1380 LDPFSQYS-------DEEV---WWALELAHLKTFVSalpdkldhecaeggENLSVGQRQLVCLARALLRKTKILVLDEAT 1449
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1387227070 646 AGLDPFSRHLVWNFLKERKTNHTILFSTQ----FMDEAdiladRKVFLSNGKLRCAGSSLFLKRKWGIGYHLS 714
Cdd:TIGR00957 1450 AAVDLETDNLIQSTIRTQFEDCTVLTIAHrlntIMDYT-----RVIVLDKGEVAEFGAPSNLLQQRGIFYSMA 1517
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
1320-1510 |
9.70e-05 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 46.41 E-value: 9.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1320 VLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRD-------SGT--PPTRqagggfRHLGYCPQEDVLWPDLTVREHLdL 1390
Cdd:PRK11144 26 ITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGrvlfdaeKGIclPPEK------RRIGYVFQDARLFPHYKVRGNL-R 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1391 YsavkGLTKEEAAL--SVSRLADALKLQDQmaLPAkALPEGAKRKLSFALSVLGSPALLLLDEPTTGMD-PEGQLQMwQA 1467
Cdd:PRK11144 99 Y----GMAKSMVAQfdKIVALLGIEPLLDR--YPG-SLSGGEKQRVAIGRALLTAPELLLMDEPLASLDlPRKRELL-PY 170
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1387227070 1468 IQAIVKSSARGALLTTHSMAEAEAVCDRVAIMVSGRLRCIGSV 1510
Cdd:PRK11144 171 LERLAREINIPILYVSHSLDEILRLADRVVVLEQGKVKAFGPL 213
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
1301-1518 |
1.03e-04 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 47.25 E-value: 1.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1301 ARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDSgtpptrqagggfrhLGYCPQEDVLWP 1380
Cdd:TIGR00957 647 ARDLPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGS--------------VAYVPQQAWIQN 712
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1381 DlTVREHLDLYSAVKGLTKEEAALSVSRLAD--ALKLQDQMALPAKA--LPEGAKRKLSFALSVLGSPALLLLDEPTTGM 1456
Cdd:TIGR00957 713 D-SLRENILFGKALNEKYYQQVLEACALLPDleILPSGDRTEIGEKGvnLSGGQKQRVSLARAVYSNADIYLFDDPLSAV 791
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1387227070 1457 DPEGQLQMWQAI---QAIVKSSARgaLLTTHSMAEAEAVcDRVAIMVSGRLRCIGSVQHLKSKFG 1518
Cdd:TIGR00957 792 DAHVGKHIFEHVigpEGVLKNKTR--ILVTHGISYLPQV-DVIIVMSGGKISEMGSYQELLQRDG 853
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
1302-1457 |
1.06e-04 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 47.09 E-value: 1.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1302 RKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFrdsgtPPTRQagggfrhLGYCPQEDvlwPD 1381
Cdd:PRK10636 11 RGVRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYTF-----PGNWQ-------LAWVNQET---PA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 LTV----------REHLDLYSAVK---------------GLTKEEAALSV-SRLADALK----LQDQMALPAKALPEGAK 1431
Cdd:PRK10636 76 LPQpaleyvidgdREYRQLEAQLHdanerndghaiatihGKLDAIDAWTIrSRAASLLHglgfSNEQLERPVSDFSGGWR 155
|
170 180
....*....|....*....|....*.
gi 1387227070 1432 RKLSFALSVLGSPALLLLDEPTTGMD 1457
Cdd:PRK10636 156 MRLNLAQALICRSDLLLLDEPTNHLD 181
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
503-660 |
1.13e-04 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 44.86 E-value: 1.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 503 ICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEIinMEEIRNYTGFcpQFNIYFDfLTVRENLRL 582
Cdd:PRK13541 19 LSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNI--AKPYCTYIGH--NLGLKLE-MTVFENLKF 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 583 FAKIKgippkeveQEVKSIMMELDMHNIQDVIAKE---LSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNF 659
Cdd:PRK13541 94 WSEIY--------NSAETLYAAIHYFKLHDLLDEKcysLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENRDLLNNL 165
|
.
gi 1387227070 660 L 660
Cdd:PRK13541 166 I 166
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
469-695 |
1.20e-04 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 46.71 E-value: 1.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 469 EPVSPEFHRKEAIRIRNLRKEYKG-KPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQ 547
Cdd:COG4615 316 AAAPPAPADFQTLELRGVTYRYPGeDGDEGFTLGPIDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQP 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 548 LSEIiNMEEIRNytgfcpQFN-IYFDFltvrenlRLFAKIKGIPPKEVEQEVKSIMMELDMHN---IQD--VIAKELSGG 621
Cdd:COG4615 396 VTAD-NREAYRQ------LFSaVFSDF-------HLFDRLLGLDGEADPARARELLERLELDHkvsVEDgrFSTTDLSQG 461
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 622 QKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLvwnFLKE-----RKTNHTILFST---QFMDeadiLADRKVFLSNGK 693
Cdd:COG4615 462 QRKRLALLVALLEDRPILVFDEWAADQDPEFRRV---FYTEllpelKARGKTVIAIShddRYFD----LADRVLKMDYGK 534
|
..
gi 1387227070 694 LR 695
Cdd:COG4615 535 LV 536
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
1311-1349 |
1.25e-04 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 46.71 E-value: 1.25e-04
10 20 30
....*....|....*....|....*....|....*....
gi 1387227070 1311 VSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVV 1349
Cdd:COG4615 351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEI 389
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
500-649 |
1.34e-04 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 46.83 E-value: 1.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 500 LQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATiYNTQLSeiinmeeirnytgFCPQFNiYFDFLTVREN 579
Cdd:TIGR01271 442 LKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIK-HSGRIS-------------FSPQTS-WIMPGTIKDN 506
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 580 LrlfakIKGIPPKEVEQE--VKSIMMELDMH---NIQDVIAKE----LSGGQKRKLTFGIAILGDPQVLLLDEPTAGLD 649
Cdd:TIGR01271 507 I-----IFGLSYDEYRYTsvIKACQLEEDIAlfpEKDKTVLGEggitLSGGQRARISLARAVYKDADLYLLDSPFTHLD 580
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
617-693 |
1.86e-04 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 46.24 E-value: 1.86e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1387227070 617 ELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE--RKTNHTILFSTQFMDEADILADRKVFLSNGK 693
Cdd:PRK15134 156 QLSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRElqQELNMGLLFITHNLSIVRKLADRVAVMQNGR 234
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
1288-1351 |
2.00e-04 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 45.47 E-value: 2.00e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1387227070 1288 HKEYKQEKKRCFSARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVF 1351
Cdd:PRK15079 17 HFDIKDGKQWFWQPPKTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAW 80
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
499-649 |
2.31e-04 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 45.85 E-value: 2.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 499 ALQGICLDVYEGQLTAILGHSGAGKSS----LLSILGgwsacTEGSATIYNTQLSEII--NMEEIRN---------YTGF 563
Cdd:PRK15134 301 VVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLIN-----SQGEIWFDGQPLHNLNrrQLLPVRHriqvvfqdpNSSL 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 564 CPQFNIyfdFLTVRENLRLFAKIkgIPPKEVEQEVKSIMME--LDMHNIQDVIAkELSGGQKRKLTFGIAILGDPQVLLL 641
Cdd:PRK15134 376 NPRLNV---LQIIEEGLRVHQPT--LSAAQREQQVIAVMEEvgLDPETRHRYPA-EFSGGQRQRIAIARALILKPSLIIL 449
|
....*...
gi 1387227070 642 DEPTAGLD 649
Cdd:PRK15134 450 DEPTSSLD 457
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
1317-1347 |
2.39e-04 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 45.93 E-value: 2.39e-04
10 20 30
....*....|....*....|....*....|.
gi 1387227070 1317 KGEVLGLLGHNGAGKSTCIKMITGDTKPTAG 1347
Cdd:COG1245 98 KGKVTGILGPNGIGKSTALKILSGELKPNLG 128
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
1298-1458 |
2.57e-04 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 45.73 E-value: 2.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1298 CFSARKTKTAVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGvVVFRDsGTPPTRQAGGGFRHlgycpqedv 1377
Cdd:PRK10522 329 TFAYQDNGFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSG-EILLD-GKPVTAEQPEDYRK--------- 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1378 lwpdltvrehldLYSAV-------------KGLTKEEAA----LSVSRLADALKLQDQMALPAKaLPEGAKRKLSFALSV 1440
Cdd:PRK10522 398 ------------LFSAVftdfhlfdqllgpEGKPANPALvekwLERLKMAHKLELEDGRISNLK-LSKGQKKRLALLLAL 464
|
170
....*....|....*...
gi 1387227070 1441 LGSPALLLLDEPTTGMDP 1458
Cdd:PRK10522 465 AEERDILLLDEWAADQDP 482
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
480-649 |
2.82e-04 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 45.88 E-value: 2.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 480 AIRIRNLRKEYKgkPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSATIYNTQLSEiINMEEIRN 559
Cdd:PLN03130 1237 SIKFEDVVLRYR--PELPPVLHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISK-FGLMDLRK 1313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 560 YTGFCPQFNIYFDFlTVRENLRLFAkikgippkevEQEVKSIMMELDMHNIQDVIAK--------------ELSGGQKRK 625
Cdd:PLN03130 1314 VLGIIPQAPVLFSG-TVRFNLDPFN----------EHNDADLWESLERAHLKDVIRRnslgldaevseageNFSVGQRQL 1382
|
170 180
....*....|....*....|....
gi 1387227070 626 LTFGIAILGDPQVLLLDEPTAGLD 649
Cdd:PLN03130 1383 LSLARALLRRSKILVLDEATAAVD 1406
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
1318-1499 |
2.91e-04 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 44.28 E-value: 2.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1318 GEVLGLLGHNGAGKSTCIKMITGDTKPTAGvvvfRDSGTPPTRQAGGGFRhlGYCPQ---EDVLWPDLTVR---EHLDLY 1391
Cdd:cd03236 26 GQVLGLVGPNGIGKSTALKILAGKLKPNLG----KFDDPPDWDEILDEFR--GSELQnyfTKLLEGDVKVIvkpQYVDLI 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1392 -SAVKG-----LTKEEAALSVSRLADALKLQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDPEGQLQMW 1465
Cdd:cd03236 100 pKAVKGkvgelLKKKDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKQRLNAA 179
|
170 180 190
....*....|....*....|....*....|....
gi 1387227070 1466 QAIQAIVKsSARGALLTTHSMAEAEAVCDRVAIM 1499
Cdd:cd03236 180 RLIRELAE-DDNYVLVVEHDLAVLDYLSDYIHCL 212
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
1311-1516 |
3.24e-04 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 45.74 E-value: 3.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1311 VSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVVVFRDS-----GTPPTRqagggfRHLGYCPQEDVLWPDlTVR 1385
Cdd:PLN03232 1255 LSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCdvakfGLTDLR------RVLSIIPQSPVLFSG-TVR 1327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1386 EHLDLYSAVK--GLTKeeaALSVSRLADALK-----LQDQMALPAKALPEGAKRKLSFALSVLGSPALLLLDEPTTGMDP 1458
Cdd:PLN03232 1328 FNIDPFSEHNdaDLWE---ALERAHIKDVIDrnpfgLDAEVSEGGENFSVGQRQLLSLARALLRRSKILVLDEATASVDV 1404
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 1459 EGQLQMWQAIQAIVKSSArgALLTTHSMaEAEAVCDRVAIMVSGRLRCIGSVQHLKSK 1516
Cdd:PLN03232 1405 RTDSLIQRTIREEFKSCT--MLVIAHRL-NTIIDCDKILVLSSGQVLEYDSPQELLSR 1459
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
1308-1522 |
4.25e-04 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 43.86 E-value: 4.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1308 VRNVSFCINKGEVLGLLGHNGAGKSTCIKMITG--DTKPTAGVVVFRDSG----TPPTRQAGGGFrhLGYcpQEDVLWPD 1381
Cdd:CHL00131 23 LKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGhpAYKILEGDILFKGESildlEPEERAHLGIF--LAF--QYPIEIPG 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1382 LTVREHLDL-YSAVK---GLTKEEAALSVSRLADALKL--QDQMALpAKALPEG-----AKRK--LSFALSvlgSPALLL 1448
Cdd:CHL00131 99 VSNADFLRLaYNSKRkfqGLPELDPLEFLEIINEKLKLvgMDPSFL-SRNVNEGfsggeKKRNeiLQMALL---DSELAI 174
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387227070 1449 LDEPTTGMDPEGQLQMWQAIQAIvKSSARGALLTTHSMAEAEAVC-DRVAIMVSGRLRCIGSVQ--HLKSKFGKDYL 1522
Cdd:CHL00131 175 LDETDSGLDIDALKIIAEGINKL-MTSENSIILITHYQRLLDYIKpDYVHVMQNGKIIKTGDAElaKELEKKGYDWL 250
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
482-533 |
6.84e-04 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 44.01 E-value: 6.84e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 482 RIRNLRKEYKGkpekVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGW 533
Cdd:NF040905 3 EMRGITKTFPG----VKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGV 50
|
|
| RsgA_GTPase |
pfam03193 |
RsgA GTPase; RsgA (also known as EngC and YjeQ) represents a protein family whose members are ... |
479-532 |
7.10e-04 |
|
RsgA GTPase; RsgA (also known as EngC and YjeQ) represents a protein family whose members are broadly conserved in bacteria and are indispensable for growth. The GTPase domain of RsgA is very similar to several P-loop GTPases, but differs in having a circular permutation of the GTPase structure described by a G4-G1-G3 pattern.
Pssm-ID: 427191 [Multi-domain] Cd Length: 174 Bit Score: 42.14 E-value: 7.10e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1387227070 479 EAIRIRNLRKEYKG---KPEKVEALQGICLD----VYEGQLTAILGHSGAGKSSLL-SILGG 532
Cdd:pfam03193 68 EEEELEELLKIYRAigyPVLFVSAKTGEGIEalkeLLKGKTTVLAGQSGVGKSTLLnALLPE 129
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
1310-1349 |
7.26e-04 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 44.11 E-value: 7.26e-04
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1387227070 1310 NVSFCINKGEVLGLLGHNGAGKSTCIKMITGDTKPTAGVV 1349
Cdd:PRK15064 19 NISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNV 58
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
1317-1344 |
1.25e-03 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 43.26 E-value: 1.25e-03
10 20
....*....|....*....|....*...
gi 1387227070 1317 KGEVLGLLGHNGAGKSTCIKMITGDTKP 1344
Cdd:PRK13409 98 EGKVTGILGPNGIGKTTAVKILSGELIP 125
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
469-695 |
1.31e-03 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 43.42 E-value: 1.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 469 EPVSPEFHRKEA------IRIRNLRKEYkgkPEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTEGSAT 542
Cdd:PRK10522 305 APYKAEFPRPQAfpdwqtLELRNVTFAY---QDNGFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEIL 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 543 IYNTQLSEIiNMEEIRNYtgfcpqfniyfdFLTVRENLRLFAKIKG-----IPPKEVEQEVKSIMM----ELDMHNIQDV 613
Cdd:PRK10522 382 LDGKPVTAE-QPEDYRKL------------FSAVFTDFHLFDQLLGpegkpANPALVEKWLERLKMahklELEDGRISNL 448
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 614 iakELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDP-FSR---HLVWNFLKErkTNHTIlFSTQFMDEADILADRKVFL 689
Cdd:PRK10522 449 ---KLSKGQKKRLALLLALAEERDILLLDEWAADQDPhFRRefyQVLLPLLQE--MGKTI-FAISHDDHYFIHADRLLEM 522
|
....*.
gi 1387227070 690 SNGKLR 695
Cdd:PRK10522 523 RNGQLS 528
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
1308-1517 |
1.52e-03 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 43.61 E-value: 1.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1308 VRNVSFCINKGEVLGLLGHNGAGKSTCI----KMItgDTKPTAGVVVFRDSGTPPTRQAGggfRHLGYCPQEDVLWpDLT 1383
Cdd:PTZ00243 1326 LRGVSFRIAPREKVGIVGRTGSGKSTLLltfmRMV--EVCGGEIRVNGREIGAYGLRELR---RQFSMIPQDPVLF-DGT 1399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 1384 VREHLD---------LYSAVKGLTKEEAALSVSRLADALKL---------QDQMALPAKALpegAKRklsfalsvlGSpA 1445
Cdd:PTZ00243 1400 VRQNVDpfleassaeVWAALELVGLRERVASESEGIDSRVLeggsnysvgQRQLMCMARAL---LKK---------GS-G 1466
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1387227070 1446 LLLLDEPTTGMDPEGQLQmwqaIQAIVKS--SARGALLTTHSMaEAEAVCDRVAIMVSGRLRCIGSVQHL----KSKF 1517
Cdd:PTZ00243 1467 FILMDEATANIDPALDRQ----IQATVMSafSAYTVITIAHRL-HTVAQYDKIIVMDHGAVAEMGSPRELvmnrQSIF 1539
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
485-674 |
1.57e-03 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 41.47 E-value: 1.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 485 NLRKEYKGKPekveALQGICLDVYEGQLTAILGHSGAGKSSLLSILGGwsactegsatIYNTQLSEIinmeeirnytgFC 564
Cdd:PRK13540 6 ELDFDYHDQP----LLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAG----------LLNPEKGEI-----------LF 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 565 PQFNIYFDFLTVRENLRLFAKIKGIPPKEVEQE-------VKSIMMELD-------MHNIQDVIAKELSGGQKRKLTFGI 630
Cdd:PRK13540 61 ERQSIKKDLCTYQKQLCFVGHRSGINPYLTLREnclydihFSPGAVGITelcrlfsLEHLIDYPCGLLSSGQKRQVALLR 140
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1387227070 631 AILGDPQVLLLDEPTAGLDPFSRHLVWNFLKE-RKTNHTILFSTQ 674
Cdd:PRK13540 141 LWMSKAKLWLLDEPLVALDELSLLTIITKIQEhRAKGGAVLLTSH 185
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
1304-1340 |
1.75e-03 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 42.85 E-value: 1.75e-03
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 1387227070 1304 TKT-----AVRNVSFCINKGEVLGLLGHNGAGKSTCIKMITG 1340
Cdd:NF040905 8 TKTfpgvkALDDVNLSVREGEIHALCGENGAGKSTLMKVLSG 49
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
618-649 |
3.55e-03 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 41.84 E-value: 3.55e-03
10 20 30
....*....|....*....|....*....|..
gi 1387227070 618 LSGGQKRKLTFGIAILGDPQVLLLDEPTAGLD 649
Cdd:PRK13549 406 LSGGNQQKAVLAKCLLLNPKILILDEPTRGID 437
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
494-650 |
3.87e-03 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 42.04 E-value: 3.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 494 PEKVEALQGICLDVYEGQLTAILGHSGAGKSSLLSILGG-WSactegsatIYNTQLSeiinmEEIRNYTGFCPQfNIYFD 572
Cdd:TIGR00954 462 PNGDVLIESLSFEVPSGNNLLICGPNGCGKSSLFRILGElWP--------VYGGRLT-----KPAKGKLFYVPQ-RPYMT 527
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 573 FLTVRENL-----RLFAKIKGIPPKEVEQevksIMMELDMHNIQ------DVIA---KELSGGQKRKLTFGIAILGDPQV 638
Cdd:TIGR00954 528 LGTLRDQIiypdsSEDMKRRGLSDKDLEQ----ILDNVQLTHILereggwSAVQdwmDVLSGGEKQRIAMARLFYHKPQF 603
|
170
....*....|..
gi 1387227070 639 LLLDEPTAGLDP 650
Cdd:TIGR00954 604 AILDECTSAVSV 615
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
503-649 |
4.13e-03 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 40.69 E-value: 4.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 503 ICLDVYEGQLTAILGHSGAGKSSLLSILGGwsaCTEGSATIY--NTQLSEIINMEEIRNYTGFCPQFNIYFDfLTVRENL 580
Cdd:PRK03695 15 LSAEVRAGEILHLVGPNGAGKSTLLARMAG---LLPGSGSIQfaGQPLEAWSAAELARHRAYLSQQQTPPFA-MPVFQYL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387227070 581 RLFakikgIPPKEVEQEVKSIMMEL-DMHNIQDVIAK---ELSGGQKRKLTFGIAIL-----GDP--QVLLLDEPTAGLD 649
Cdd:PRK03695 91 TLH-----QPDKTRTEAVASALNEVaEALGLDDKLGRsvnQLSGGEWQRVRLAAVVLqvwpdINPagQLLLLDEPMNSLD 165
|
|
| YjeQ_EngC |
cd01854 |
Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; ... |
494-532 |
8.00e-03 |
|
Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; YjeQ (YloQ in Bacillus subtilis) is a ribosomal small subunit-dependent GTPase; hence also known as RsgA. YjeQ is a late-stage ribosomal biogenesis factor involved in the 30S subunit maturation, and it represents a protein family whose members are broadly conserved in bacteria and have been shown to be essential to the growth of E. coli and B. subtilis. Proteins of the YjeQ family contain all sequence motifs typical of the vast class of P-loop-containing GTPases, but show a circular permutation, with a G4-G1-G3 pattern of motifs as opposed to the regular G1-G3-G4 pattern seen in most GTPases. All YjeQ family proteins display a unique domain architecture, which includes an N-terminal OB-fold RNA-binding domain, the central permuted GTPase domain, and a zinc knuckle-like C-terminal cysteine domain.
Pssm-ID: 206747 [Multi-domain] Cd Length: 211 Bit Score: 39.69 E-value: 8.00e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1387227070 494 PEKVEALQGICldvyEGQLTAILGHSGAGKSSLL-SILGG 532
Cdd:cd01854 73 GEGLDELRELL----KGKTSVLVGQSGVGKSTLLnALLPE 108
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
616-653 |
8.29e-03 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 40.77 E-value: 8.29e-03
10 20 30
....*....|....*....|....*....|....*...
gi 1387227070 616 KELSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPFSR 653
Cdd:PRK10938 134 KYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASR 171
|
|
| |
