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Conserved domains on  [gi|512833166|ref|XP_004913406|]
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homeobox protein aristaless-like 4 [Xenopus tropicalis]

Protein Classification

homeodomain and OAR domain-containing protein( domain architecture ID 13432694)

homeodomain and OAR domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
182-238 6.93e-33

Homeodomain;


:

Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 117.22  E-value: 6.93e-33
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 512833166  182 RRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRK 238
Cdd:pfam00046   1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
COG5576 super family cl35021
Homeodomain-containing transcription factor [Transcription];
120-266 2.84e-16

Homeodomain-containing transcription factor [Transcription];


The actual alignment was detected with superfamily member COG5576:

Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 75.55  E-value: 2.84e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512833166 120 SPGDPLIPCYAKESALTPNSdhQGMdsgYITSKETAGKgsqdrgSGDLPMDKTESESNKGKKRRNRTTFTSYQLEELEKV 199
Cdd:COG5576    1 SPVQPMQPLSALESQRMPQI--RTI---KTTKNKREVE------AADSEMKLERKQDGSSPPKSKRRRTTDEQLMVLERE 69

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 512833166 200 FQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSSAYELPLLTRAEN 266
Cdd:COG5576   70 FEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRAKEKKKRSGKVEQRPGEEEADLAKIGSLSTGQI 136
OAR pfam03826
OAR motif; The entry represents the OAR motif.
 352-370 9.60e-08

OAR motif; The entry represents the OAR motif.


:

Pssm-ID: 461067  Cd Length: 19  Bit Score: 47.41  E-value: 9.60e-08
                          10
                  ....*....|....*....
gi 512833166  352 DRKSSSIAALRMKAKEHSA 370
Cdd:pfam03826   1 DRRSSSIASLRLKAKEHSA 19
 
Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
182-238 6.93e-33

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 117.22  E-value: 6.93e-33
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 512833166  182 RRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRK 238
Cdd:pfam00046   1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 181-237 2.59e-27

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 102.33  E-value: 2.59e-27
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 512833166   181 KRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWR 237
Cdd:smart00389   1 KRRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 182-240 9.99e-27

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 100.78  E-value: 9.99e-27
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 512833166 182 RRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRE 240
Cdd:cd00086    1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRSE 59
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
120-266 2.84e-16

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 75.55  E-value: 2.84e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512833166 120 SPGDPLIPCYAKESALTPNSdhQGMdsgYITSKETAGKgsqdrgSGDLPMDKTESESNKGKKRRNRTTFTSYQLEELEKV 199
Cdd:COG5576    1 SPVQPMQPLSALESQRMPQI--RTI---KTTKNKREVE------AADSEMKLERKQDGSSPPKSKRRRTTDEQLMVLERE 69

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 512833166 200 FQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSSAYELPLLTRAEN 266
Cdd:COG5576   70 FEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRAKEKKKRSGKVEQRPGEEEADLAKIGSLSTGQI 136
OAR pfam03826
OAR motif; The entry represents the OAR motif.
 352-370 9.60e-08

OAR motif; The entry represents the OAR motif.


Pssm-ID: 461067  Cd Length: 19  Bit Score: 47.41  E-value: 9.60e-08
                          10
                  ....*....|....*....
gi 512833166  352 DRKSSSIAALRMKAKEHSA 370
Cdd:pfam03826   1 DRRSSSIASLRLKAKEHSA 19
 
Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
182-238 6.93e-33

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 117.22  E-value: 6.93e-33
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 512833166  182 RRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRK 238
Cdd:pfam00046   1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 181-237 2.59e-27

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 102.33  E-value: 2.59e-27
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 512833166   181 KRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWR 237
Cdd:smart00389   1 KRRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 182-240 9.99e-27

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 100.78  E-value: 9.99e-27
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 512833166 182 RRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRE 240
Cdd:cd00086    1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRSE 59
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
120-266 2.84e-16

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 75.55  E-value: 2.84e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512833166 120 SPGDPLIPCYAKESALTPNSdhQGMdsgYITSKETAGKgsqdrgSGDLPMDKTESESNKGKKRRNRTTFTSYQLEELEKV 199
Cdd:COG5576    1 SPVQPMQPLSALESQRMPQI--RTI---KTTKNKREVE------AADSEMKLERKQDGSSPPKSKRRRTTDEQLMVLERE 69

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 512833166 200 FQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSSAYELPLLTRAEN 266
Cdd:COG5576   70 FEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRAKEKKKRSGKVEQRPGEEEADLAKIGSLSTGQI 136
OAR pfam03826
OAR motif; The entry represents the OAR motif.
 352-370 9.60e-08

OAR motif; The entry represents the OAR motif.


Pssm-ID: 461067  Cd Length: 19  Bit Score: 47.41  E-value: 9.60e-08
                          10
                  ....*....|....*....
gi 512833166  352 DRKSSSIAALRMKAKEHSA 370
Cdd:pfam03826   1 DRRSSSIASLRLKAKEHSA 19
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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