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Conserved domains on  [gi|1333701087|ref|XP_001915582|]
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anaphase-promoting complex subunit 7 isoform X1 [Equus caballus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 338-550 1.02e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 86.71  E-value: 1.02e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 338 AEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYL 417
Cdd:COG2956     8 ALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 418 ASNSIREAMVMANNVYKTLGANAQTLTLLATVCLE--DPvtqEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGI 495
Cdd:COG2956    88 KAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQegDW---EKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAI 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1333701087 496 ALLRNALANQSDCV-LHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQK 550
Cdd:COG2956   165 EALEKALKLDPDCArALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAE 220
PEP_TPR_lipo super family cl37187
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 132-425 1.61e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


The actual alignment was detected with superfamily member TIGR02917:

Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.16  E-value: 1.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 132 PSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQR-TPKINMMLANLYKKAGQERPSVTSYKEVLRQCP---LALdAILG 207
Cdd:TIGR02917 564 PQEIEPALALAQYYLGKGQLKKALAILNEAADAAPdSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPdsaLAL-LLLA 642

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 208 LLSLSVKG-AEVASMTMNVIQTVPNLdWLSVWIKAYAFVHTGDNSRAINTICSLEKKSLLRDNVDLLgsLADLYFRAGDN 286
Cdd:TIGR02917 643 DAYAVMKNyAKAITSLKRALELKPDN-TEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFEL--EGDLYLRQKDY 719

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 287 KNSVLKFEQAQMLDPYLIKGMDVYGYLLAR------EGRLEDV-----------------------ENLGCRLFNISDQH 337
Cdd:TIGR02917 720 PAAIQAYRKALKRAPSSQNAIKLHRALLASgntaeaVKTLEAWlkthpndavlrtalaelylaqkdYDKAIKHYQTVVKK 799

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 338 AE--PWVVSGCHSFYSKRY-SRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIE 414
Cdd:TIGR02917 800 APdnAVVLNNLAWLYLELKdPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLAL 879

                         330
                  ....*....|.
gi 1333701087 415 CYLASNSIREA 425
Cdd:TIGR02917 880 ALLATGRKAEA 890
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 338-550 1.02e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 86.71  E-value: 1.02e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 338 AEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYL 417
Cdd:COG2956     8 ALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 418 ASNSIREAMVMANNVYKTLGANAQTLTLLATVCLE--DPvtqEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGI 495
Cdd:COG2956    88 KAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQegDW---EKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAI 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1333701087 496 ALLRNALANQSDCV-LHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQK 550
Cdd:COG2956   165 EALEKALKLDPDCArALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAE 220
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 178-568 9.43e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 58.56  E-value: 9.43e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 178 YKKAGQERPSVTSYKEVLRQCPLALDA--ILGLLSL---SVKGAE-----VASMTMNVIQTVPNLdwlsvwikAYAFVHT 247
Cdd:TIGR02917  32 YLQKNKYKAAIIQLKNALQKDPNDAEArfLLGKIYLalgDYAAAEkelrkALSLGYPKNQVLPLL--------ARAYLLQ 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 248 GDNSRAINTicsLEKKSLLRDN--VDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVEN 325
Cdd:TIGR02917 104 GKFQQVLDE---LPGKTLLDDEgaAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARA 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 326 LGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCR 405
Cdd:TIGR02917 181 LIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNS 260

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 406 LDC--YEGLIEcyLASNSIREAMvmaNNVYKTLGANAQTLT--LLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKK 481
Cdd:TIGR02917 261 PLAhyLKALVD--FQKKNYEDAR---ETLQDALKSAPEYLPalLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLL 335

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 482 AELLSREQKYEDGIALLRNALA-NQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPND-----QKSLEGMQKMEKEE 555
Cdd:TIGR02917 336 ASIQLRLGRVDEAIATLSPALGlDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENaaartQLGISKLSQGDPSE 415

                         410
                  ....*....|...
gi 1333701087 556 SPTDATQEEDVDD 568
Cdd:TIGR02917 416 AIADLETAAQLDP 428
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 132-425 1.61e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.16  E-value: 1.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 132 PSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQR-TPKINMMLANLYKKAGQERPSVTSYKEVLRQCP---LALdAILG 207
Cdd:TIGR02917 564 PQEIEPALALAQYYLGKGQLKKALAILNEAADAAPdSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPdsaLAL-LLLA 642

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 208 LLSLSVKG-AEVASMTMNVIQTVPNLdWLSVWIKAYAFVHTGDNSRAINTICSLEKKSLLRDNVDLLgsLADLYFRAGDN 286
Cdd:TIGR02917 643 DAYAVMKNyAKAITSLKRALELKPDN-TEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFEL--EGDLYLRQKDY 719

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 287 KNSVLKFEQAQMLDPYLIKGMDVYGYLLAR------EGRLEDV-----------------------ENLGCRLFNISDQH 337
Cdd:TIGR02917 720 PAAIQAYRKALKRAPSSQNAIKLHRALLASgntaeaVKTLEAWlkthpndavlrtalaelylaqkdYDKAIKHYQTVVKK 799

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 338 AE--PWVVSGCHSFYSKRY-SRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIE 414
Cdd:TIGR02917 800 APdnAVVLNNLAWLYLELKdPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLAL 879

                         330
                  ....*....|.
gi 1333701087 415 CYLASNSIREA 425
Cdd:TIGR02917 880 ALLATGRKAEA 890
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
279-403 1.52e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.92  E-value: 1.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 279 LYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLgcrlfnisdqhaepwvvsgchsfyskrysral 358
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-------------------------------- 48

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1333701087 359 ylgAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAP 403
Cdd:COG3063    49 ---EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDP 90
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 372-403 1.24e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.66  E-value: 1.24e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1333701087  372 VQALLLKGAALRNMGRVQEAIIHFREAIRLAP 403
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDP 32
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 372-403 1.81e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 35.96  E-value: 1.81e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1333701087 372 VQALLLKGAALRNMGRVQEAIIHFREAIRLAP 403
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDP 32
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 338-550 1.02e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 86.71  E-value: 1.02e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 338 AEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYL 417
Cdd:COG2956     8 ALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 418 ASNSIREAMVMANNVYKTLGANAQTLTLLATVCLE--DPvtqEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGI 495
Cdd:COG2956    88 KAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQegDW---EKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAI 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1333701087 496 ALLRNALANQSDCV-LHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQK 550
Cdd:COG2956   165 EALEKALKLDPDCArALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAE 220
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 352-562 1.45e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 85.94  E-value: 1.45e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 352 KRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANN 431
Cdd:COG2956    56 GEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLER 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 432 VYKTLGANAQTLTLLATVCLE--DPvtqEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALA-NQSDC 508
Cdd:COG2956   136 LLKLGPENAHAYCELAELYLEqgDY---DEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEqDPDYL 212

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1333701087 509 VLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDATQ 562
Cdd:COG2956   213 PALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLEAALA 266
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
365-541 4.74e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.12  E-value: 4.74e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 365 IQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLT 444
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 445 LLATVC--LEDPvtqEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCV-LHRILGDFLVAV 521
Cdd:COG0457    81 NLGLALqaLGRY---EEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDAdALYNLGIALEKL 157

                         170       180
                  ....*....|....*....|
gi 1333701087 522 NEYQEAMDQYSIALSLDPND 541
Cdd:COG0457   158 GRYEEALELLEKLEAAALAA 177
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 276-538 9.93e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 77.85  E-value: 9.93e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 276 LADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYS 355
Cdd:COG2956    14 KGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLD 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 356 RALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKT 435
Cdd:COG2956    94 RAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKL 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 436 LGANAQTLTLLATVCLE--DPvtqEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRI 513
Cdd:COG2956   174 DPDCARALLLLAELYLEqgDY---EEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLA 250

                         250       260
                  ....*....|....*....|....*
gi 1333701087 514 LGDFLVAVNEYQEAMDQYSIALSLD 538
Cdd:COG2956   251 LADLLERKEGLEAALALLERQLRRH 275
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 353-543 1.62e-15

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 80.04  E-value: 1.62e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 353 RYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMvmannv 432
Cdd:COG3914    59 LLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEAL------ 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 433 yktlganaqtltllatvcledpvtqekakTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCV-LH 511
Cdd:COG3914   133 -----------------------------AALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAeAL 183

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1333701087 512 RILGDFLVAVNEYQEAMDQYSIALSLDPNDQK 543
Cdd:COG3914   184 NNLGNALQDLGRLEEAIAAYRRALELDPDNAD 215
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 241-471 7.46e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 72.07  E-value: 7.46e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 241 AYAFVHTGDNSRAINTICSLEKKSllRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRL 320
Cdd:COG2956    49 GNLYRRRGEYDRAIRIHQKLLERD--PDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDW 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 321 EDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIR 400
Cdd:COG2956   127 EKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALE 206

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1333701087 401 LAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLAtvCLEDPVTQEKAKTLLDKALTQR 471
Cdd:COG2956   207 QDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALAD--LLERKEGLEAALALLERQLRRH 275
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
268-503 2.32e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 70.04  E-value: 2.32e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 268 DNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCH 347
Cdd:COG0457     6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 348 SFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMV 427
Cdd:COG0457    86 LQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALE 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 428 M----ANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALA 503
Cdd:COG0457   166 LleklEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYRA 245
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 266-425 1.93e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 66.94  E-value: 1.93e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 266 LRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSG 345
Cdd:COG3914    74 LLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLG 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 346 CHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREA 425
Cdd:COG3914   154 EALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVY 233
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
299-540 4.67e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.49  E-value: 4.67e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 299 LDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLK 378
Cdd:COG0457     3 LDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 379 GAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLAtVCLEDPVTQE 458
Cdd:COG0457    83 GLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLG-IALEKLGRYE 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 459 KAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLD 538
Cdd:COG0457   162 EALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALY 241


                  ..
gi 1333701087 539 PN 540
Cdd:COG0457   242 QY 243
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 311-446 9.00e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 64.63  E-value: 9.00e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 311 GYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQE 390
Cdd:COG3914    85 ALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEE 164

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1333701087 391 AIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLL 446
Cdd:COG3914   165 AIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 276-477 9.32e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 64.63  E-value: 9.32e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 276 LADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYS---- 351
Cdd:COG3914     7 LALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLElaal 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 352 -----KRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAM 426
Cdd:COG3914    87 llqalGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAI 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1333701087 427 VMANNVYKTLGANAQTLTLLATVcLEDPVTQEKAKTLLDKALTQRPDYIKA 477
Cdd:COG3914   167 AALRRALELDPDNAEALNNLGNA-LQDLGRLEEAIAAYRRALELDPDNADA 216
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 369-541 9.93e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 57.12  E-value: 9.93e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 369 SNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVmannvyktlganaqtltllat 448
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIV--------------------- 59

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 449 vcledpvtqekaktLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCV-LHRILGDFLVAVNEYQEA 527
Cdd:COG4783    60 --------------LLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPeAYLRLARAYRALGRPDEA 125

                         170
                  ....*....|....
gi 1333701087 528 MDQYSIALSLDPND 541
Cdd:COG4783   126 IAALEKALELDPDD 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 335-507 2.01e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 56.35  E-value: 2.01e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 335 DQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPcrldcYEGLIE 414
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDP-----DEPEAR 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 415 CYLAsnsirEAMVMANNVyktlganaqtltllatvcledpvtqEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDG 494
Cdd:COG4783    76 LNLG-----LALLKAGDY-------------------------DEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEA 125

                         170
                  ....*....|...
gi 1333701087 495 IALLRNALANQSD 507
Cdd:COG4783   126 IAALEKALELDPD 138
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 363-484 3.51e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.40  E-value: 3.51e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 363 KAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQT 442
Cdd:COG4235     8 QALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEA 87

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1333701087 443 LTLLATVCLE--DPvtqEKAKTLLDKALTQRPDYIKAVVKKAEL 484
Cdd:COG4235    88 LYLLGLAAFQqgDY---AEAIAAWQKLLALLPADAPARLLEASI 128
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 310-425 9.31e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.43  E-value: 9.31e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 310 YGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQ 389
Cdd:COG4783    10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1333701087 390 EAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREA 425
Cdd:COG4783    90 EALALLEKALKLDPEHPEAYLRLARAYRALGRPDEA 125
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 178-568 9.43e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 58.56  E-value: 9.43e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 178 YKKAGQERPSVTSYKEVLRQCPLALDA--ILGLLSL---SVKGAE-----VASMTMNVIQTVPNLdwlsvwikAYAFVHT 247
Cdd:TIGR02917  32 YLQKNKYKAAIIQLKNALQKDPNDAEArfLLGKIYLalgDYAAAEkelrkALSLGYPKNQVLPLL--------ARAYLLQ 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 248 GDNSRAINTicsLEKKSLLRDN--VDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVEN 325
Cdd:TIGR02917 104 GKFQQVLDE---LPGKTLLDDEgaAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARA 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 326 LGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCR 405
Cdd:TIGR02917 181 LIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNS 260

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 406 LDC--YEGLIEcyLASNSIREAMvmaNNVYKTLGANAQTLT--LLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKK 481
Cdd:TIGR02917 261 PLAhyLKALVD--FQKKNYEDAR---ETLQDALKSAPEYLPalLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLL 335

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 482 AELLSREQKYEDGIALLRNALA-NQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPND-----QKSLEGMQKMEKEE 555
Cdd:TIGR02917 336 ASIQLRLGRVDEAIATLSPALGlDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENaaartQLGISKLSQGDPSE 415

                         410
                  ....*....|...
gi 1333701087 556 SPTDATQEEDVDD 568
Cdd:TIGR02917 416 AIADLETAAQLDP 428
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 240-542 7.28e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 55.47  E-value: 7.28e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 240 KAYAFVHTGDNSRAINticSLEKK-SLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREG 318
Cdd:TIGR02917 471 LGAIYLGKGDLAKARE---AFEKAlSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTG 547

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 319 RLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREA 398
Cdd:TIGR02917 548 NEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKL 627

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 399 IRLAPcrldcYEGLIECYLAsnsirEAMVMANNVyktlganaqtltllatvcledpvtqEKAKTLLDKALTQRPDYIKAV 478
Cdd:TIGR02917 628 LALQP-----DSALALLLLA-----DAYAVMKNY-------------------------AKAITSLKRALELKPDNTEAQ 672

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1333701087 479 VKKAELLSREQKYEDGIALLRN-ALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQ 542
Cdd:TIGR02917 673 IGLAQLLLAAKRTESAKKIAKSlQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQ 737
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 276-403 7.90e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 51.73  E-value: 7.90e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 276 LADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYS 355
Cdd:COG4783    10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1333701087 356 RALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAP 403
Cdd:COG4783    90 EALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
439-548 1.53e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 52.70  E-value: 1.53e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 439 NAQTLTLLATVC--LEDPvtqEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRI-LG 515
Cdd:COG0457     7 DAEAYNNLGLAYrrLGRY---EEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNnLG 83

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1333701087 516 DFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGM 548
Cdd:COG0457    84 LALQALGRYEEALEDYDKALELDPDDAEALYNL 116
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 354-542 3.41e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 53.55  E-value: 3.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 354 YSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVY 433
Cdd:TIGR02917 379 FEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKALAAAKKLE 458

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 434 KTLGANAQTLTLLATVCL--EDPvtqEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALA-NQSDCVL 510
Cdd:TIGR02917 459 KKQPDNASLHNLLGAIYLgkGDL---AKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTiDPKNLRA 535

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1333701087 511 HRILGDFLVAVNEYQEAMDQYSIALSLDPNDQ 542
Cdd:TIGR02917 536 ILALAGLYLRTGNEEEAVAWLEKAAELNPQEI 567
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 269-541 1.68e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 51.24  E-value: 1.68e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 269 NVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHS 348
Cdd:TIGR02917 532 NLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQ 611

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 349 FYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVM 428
Cdd:TIGR02917 612 LAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKI 691

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 429 ANNVYKTLGANAQTLTLLATVCLEDPVTQEkAKTLLDKALTQRPDYiKAVVKKAELLSREQKYEDGIALLRNALANQ-SD 507
Cdd:TIGR02917 692 AKSLQKQHPKAALGFELEGDLYLRQKDYPA-AIQAYRKALKRAPSS-QNAIKLHRALLASGNTAEAVKTLEAWLKTHpND 769

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1333701087 508 CVLHRILGDFLVAVNEYQEAMDQYSIALSLDPND 541
Cdd:TIGR02917 770 AVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDN 803
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
458-540 2.36e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 45.93  E-value: 2.36e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 458 EKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSL 537
Cdd:COG3063     9 EEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALEL 88


                  ...
gi 1333701087 538 DPN 540
Cdd:COG3063    89 DPS 91
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 290-403 2.97e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.92  E-value: 2.97e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 290 VLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNS 369
Cdd:COG4235     3 IARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDP 82

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1333701087 370 NSVQALLLKGAALRNMGRVQEAIIHFREAIRLAP 403
Cdd:COG4235    83 DNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLP 116
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 459-545 3.00e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.92  E-value: 3.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 459 KAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALA-NQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSL 537
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRlDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80


                  ....*...
gi 1333701087 538 DPNDQKSL 545
Cdd:COG4235    81 DPDNPEAL 88
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 458-541 6.42e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.77  E-value: 6.42e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 458 EKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCV-LHRILGDFLVAVNEYQEAMDQYSIALS 536
Cdd:COG4235    34 DEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPeALYLLGLAAFQQGDYAEAIAAWQKLLA 113


                  ....*
gi 1333701087 537 LDPND 541
Cdd:COG4235   114 LLPAD 118
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 132-425 1.61e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.16  E-value: 1.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 132 PSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQR-TPKINMMLANLYKKAGQERPSVTSYKEVLRQCP---LALdAILG 207
Cdd:TIGR02917 564 PQEIEPALALAQYYLGKGQLKKALAILNEAADAAPdSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPdsaLAL-LLLA 642

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 208 LLSLSVKG-AEVASMTMNVIQTVPNLdWLSVWIKAYAFVHTGDNSRAINTICSLEKKSLLRDNVDLLgsLADLYFRAGDN 286
Cdd:TIGR02917 643 DAYAVMKNyAKAITSLKRALELKPDN-TEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFEL--EGDLYLRQKDY 719

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 287 KNSVLKFEQAQMLDPYLIKGMDVYGYLLAR------EGRLEDV-----------------------ENLGCRLFNISDQH 337
Cdd:TIGR02917 720 PAAIQAYRKALKRAPSSQNAIKLHRALLASgntaeaVKTLEAWlkthpndavlrtalaelylaqkdYDKAIKHYQTVVKK 799

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 338 AE--PWVVSGCHSFYSKRY-SRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIE 414
Cdd:TIGR02917 800 APdnAVVLNNLAWLYLELKdPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLAL 879

                         330
                  ....*....|.
gi 1333701087 415 CYLASNSIREA 425
Cdd:TIGR02917 880 ALLATGRKAEA 890
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 295-425 2.94e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.57  E-value: 2.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 295 QAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQA 374
Cdd:COG5010    11 PLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPEL 90

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1333701087 375 LLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREA 425
Cdd:COG5010    91 YYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEA 141
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 458-539 8.12e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.41  E-value: 8.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 458 EKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALA-NQSDCVLHRILGDFLVAVNEYQEAMDQYSIALS 536
Cdd:COG5010    71 EESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALAlSPDNPNAYSNLAALLLSLGQDDEAKAALQRALG 150


                  ...
gi 1333701087 537 LDP 539
Cdd:COG5010   151 TSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
279-403 1.52e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.92  E-value: 1.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 279 LYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLgcrlfnisdqhaepwvvsgchsfyskrysral 358
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-------------------------------- 48

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1333701087 359 ylgAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAP 403
Cdd:COG3063    49 ---EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDP 90
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 294-403 1.96e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.25  E-value: 1.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 294 EQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQ 373
Cdd:COG5010    44 AAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPN 123

                          90       100       110
                  ....*....|....*....|....*....|
gi 1333701087 374 ALLLKGAALRNMGRVQEAIIHFREAIRLAP 403
Cdd:COG5010   124 AYSNLAALLLSLGQDDEAKAALQRALGTSP 153
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
345-418 6.31e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 41.44  E-value: 6.31e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1333701087 345 GCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCrlDCYEGLIEcYLA 418
Cdd:COG4785   114 GLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPN--DPERALWL-YLA 184
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 353-472 1.23e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.94  E-value: 1.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 353 RYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNV 432
Cdd:COG5010    35 NNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKA 114

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1333701087 433 YKTLGANAQTLTLLATVcLEDPVTQEKAKTLLDKALTQRP 472
Cdd:COG5010   115 LALSPDNPNAYSNLAAL-LLSLGQDDEAKAALQRALGTSP 153
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 372-403 1.24e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.66  E-value: 1.24e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1333701087  372 VQALLLKGAALRNMGRVQEAIIHFREAIRLAP 403
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDP 32
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 372-403 1.81e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 35.96  E-value: 1.81e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1333701087 372 VQALLLKGAALRNMGRVQEAIIHFREAIRLAP 403
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDP 32
TPR_1 pfam00515
Tetratricopeptide repeat;
372-403 2.28e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.86  E-value: 2.28e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1333701087 372 VQALLLKGAALRNMGRVQEAIIHFREAIRLAP 403
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNP 32
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
381-507 4.96e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 36.69  E-value: 4.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 381 ALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVmannvyktlganaqtltllatvcledpvtqeka 460
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA--------------------------------- 47

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1333701087 461 ktlLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSD 507
Cdd:COG3063    48 ---LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPS 91
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 248-578 7.85e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 39.30  E-value: 7.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 248 GDNSRAINTICSLEKKSllRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDP-----YLIKGMdvyGYLL---AREG- 318
Cdd:TIGR02917 343 GRVDEAIATLSPALGLD--PDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPenaaaRTQLGI---SKLSqgdPSEAi 417

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 319 -RLEDVENLGCRLfnisdQHAEPWVVSgcHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFRE 397
Cdd:TIGR02917 418 aDLETAAQLDPEL-----GRADLLLIL--SYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEK 490

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 398 AIRLAP---------CRLDCYEGLIEcylASNSIREAMVMAN-----------NVYKTLGANAQTLTLLATVCLEDPVTQ 457
Cdd:TIGR02917 491 ALSIEPdffpaaanlARIDIQEGNPD---DAIQRFEKVLTIDpknlrailalaGLYLRTGNEEEAVAWLEKAAELNPQEI 567

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 458 EKAKTL---------LDKALTQRPDYIKAVVKKAE---LLSREQ----KYEDGIALLRNALANQSDCVL-HRILGDFLVA 520
Cdd:TIGR02917 568 EPALALaqyylgkgqLKKALAILNEAADAAPDSPEawlMLGRAQlaagDLNKAVSSFKKLLALQPDSALaLLLLADAYAV 647

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1333701087 521 VNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDAT-------QEEDVDDMEGSGEEGDL 578
Cdd:TIGR02917 648 MKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAkkiakslQKQHPKAALGFELEGDL 712
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 132-326 8.56e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 38.56  E-value: 8.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 132 PSEIEVKYKMAECYTMLKQDKDAIAILD-GIPSRQRTPKINMMLANLYKKAGQERPSVTSYKEVLRQCPLALDAILGLls 210
Cdd:COG2956   107 PDDAEALRLLAEIYEQEGDWEKAIEVLErLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLL-- 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333701087 211 lsvkgaevasmtmnviqtvpnldwlsvwikAYAFVHTGDNSRAINTICSLEKKSllRDNVDLLGSLADLYFRAGDNKNSV 290
Cdd:COG2956   185 ------------------------------AELYLEQGDYEEAIAALERALEQD--PDYLPALPRLAELYEKLGDPEEAL 232

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1333701087 291 LKFEQAQMLDPYLIKgMDVYGYLLAREGRLEDVENL 326
Cdd:COG2956   233 ELLRKALELDPSDDL-LLALADLLERKEGLEAALAL 267
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
352-403 8.72e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 37.97  E-value: 8.72e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1333701087 352 KRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAP 403
Cdd:COG4785    87 GDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDP 138
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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