|
Name |
Accession |
Description |
Interval |
E-value |
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
501-680 |
9.52e-39 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 145.48 E-value: 9.52e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 501 KAGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKA 580
Cdd:COG0666 96 RNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEA 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 581 GASIDATSINNSTPLSRAIESCRLDTVKYLLDMGAKFQIENRKGHAAMDIAKAYADYRIIDMIKEKLDNLPKQADNQKMK 660
Cdd:COG0666 176 GADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTA 255
|
170 180
....*....|....*....|
gi 28316764 661 GKLPKLKTEGTDVKKEEETL 680
Cdd:COG0666 256 LLLAAAAGAALIVKLLLLAL 275
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
501-656 |
3.31e-32 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 126.99 E-value: 3.31e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 501 KAGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKA 580
Cdd:COG0666 129 YNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEA 208
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 28316764 581 GASIDATSINNSTPLSRAIESCRLDTVKYLLDMGAKFQIENRKGHAAMDIAKAYADYRIIDMIKEKLDNLPKQADN 656
Cdd:COG0666 209 GADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLD 284
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
494-646 |
3.82e-32 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 126.61 E-value: 3.82e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 494 ANISFITKAGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDI 573
Cdd:COG0666 56 LLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEI 135
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 28316764 574 VELLVKAGASIDATSINNSTPLSRAIESCRLDTVKYLLDMGAKFQIENRKGHAAMDIAKAYADYRIIDMIKEK 646
Cdd:COG0666 136 VKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEA 208
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
28-320 |
2.00e-27 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 112.74 E-value: 2.00e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 28 IEKLTRLGYPELINFTEPIDGLSALHLASISNDTDMVSFLLKLGAHPDVQDHMGCTPTMRAAELGHELSMEILAKAKADM 107
Cdd:COG0666 1 LLLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 108 TIVDNEGKGVLFYCIlpTKRHYRCSLIALEHGADVNNITYEGKPVFLRACEEAHdvKDMCLTFLEKGANPNAINtSTGRT 187
Cdd:COG0666 81 NAKDDGGNTLLHAAA--RNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGN--LEIVKLLLEAGADVNAQD-NDGNT 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 188 ALMESSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMDGNTPLHFAAMGGFADCC 267
Cdd:COG0666 156 PLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIV 235
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 28316764 268 KYIAQRGCDLKWKNLEHKTPRVVAKDGGFKAASKEIRRAERTAAKLAKTGAKN 320
Cdd:COG0666 236 KLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTL 288
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
25-286 |
2.26e-27 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 112.74 E-value: 2.26e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 25 KKQIEKLTRLGYPELINFTEPIDGLSALHLASISNDTDMVSFLLKLGAHPDVQDHMGCTPTMRAAELGHELSMEILAKAK 104
Cdd:COG0666 31 LLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAG 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 105 ADMTIVDNEGKGVLFYCILptKRHYRCSLIALEHGADVNNITYEGKPVFLRACEEAHdvKDMCLTFLEKGANPNAINTSt 184
Cdd:COG0666 111 ADVNARDKDGETPLHLAAY--NGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGN--LEIVKLLLEAGADVNARDND- 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 185 GRTALMESSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMDGNTPLHFAAMGGFA 264
Cdd:COG0666 186 GETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAA 265
|
250 260
....*....|....*....|..
gi 28316764 265 DCCKYIAQRGCDLKWKNLEHKT 286
Cdd:COG0666 266 LIVKLLLLALLLLAAALLDLLT 287
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
28-255 |
4.41e-26 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 108.89 E-value: 4.41e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 28 IEKLTRLGYPELINFTEPIDGLSALHLASISNDTDMVSFLLKLGAHPDVQDHMGCTPTMRAAELGHELSMEILAKAKADM 107
Cdd:COG0666 67 LLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADV 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 108 TIVDNEGKGVLFYCILptKRHYRCSLIALEHGADVNNITYEGKPVFLRACEEAHdvKDMCLTFLEKGANPNAINTStGRT 187
Cdd:COG0666 147 NAQDNDGNTPLHLAAA--NGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGH--LEIVKLLLEAGADVNAKDND-GKT 221
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 28316764 188 ALMESSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMDGNTPL 255
Cdd:COG0666 222 ALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTLL 289
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
67-352 |
3.01e-24 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 103.50 E-value: 3.01e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 67 LLKLGAHPDVQDHMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGVLFYCILPTKRHYRCSLIALEHGADVNNIT 146
Cdd:COG0666 5 LLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 147 YEGKPVFLRACEEAHdvKDMCLTFLEKGANPNAINTStGRTALMESSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAA 226
Cdd:COG0666 85 DGGNTLLHAAARNGD--LEIVKLLLEAGADVNARDKD-GETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 227 KGGFFDILKLLFAYNGDMGLIGMDGNTPLHFAAMGGFADCCKYIAQRGCDLKWKNLEHKTPRVVAKDGGFKAASKEIRRA 306
Cdd:COG0666 162 ANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEA 241
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 28316764 307 ErtAAKLAKTGAKNPNPLWALRLHDWSIEHETSLRNAFKFVDRGDG 352
Cdd:COG0666 242 G--ADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDL 285
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
529-621 |
1.52e-22 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 92.49 E-value: 1.52e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 529 LMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKaGASIDATSiNNSTPLSRAIESCRLDTVK 608
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLE-HADVNLKD-NGRTALHYAARSGHLEIVK 78
|
90
....*....|...
gi 28316764 609 YLLDMGAKFQIEN 621
Cdd:pfam12796 79 LLLEKGADINVKD 91
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
501-628 |
8.10e-21 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 93.48 E-value: 8.10e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 501 KAGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKA 580
Cdd:COG0666 162 ANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEA 241
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 28316764 581 GASIDATSINNSTPLSRAIESCRLDTVKYLLDMGAKFQIENRKGHAAM 628
Cdd:COG0666 242 GADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTLL 289
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
501-587 |
3.03e-19 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 82.86 E-value: 3.03e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 501 KAGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKgANVNATDNfLWTPLHFACHAGQQDIVELLVKA 580
Cdd:pfam12796 6 KNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDN-GRTALHYAARSGHLEIVKLLLEK 83
|
....*..
gi 28316764 581 GASIDAT 587
Cdd:pfam12796 84 GADINVK 90
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
486-644 |
2.28e-18 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 86.16 E-value: 2.28e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 486 IDDPSRVFANISFITKAGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFA 565
Cdd:COG0666 15 LLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAA 94
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 28316764 566 CHAGQQDIVELLVKAGASIDATSINNSTPLSRAIESCRLDTVKYLLDMGAKFQIENRKGHAAMDIAkayADYRIIDMIK 644
Cdd:COG0666 95 ARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLA---AANGNLEIVK 170
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
498-658 |
2.51e-15 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 79.24 E-value: 2.51e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 498 FITKAGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELL 577
Cdd:PHA02874 130 YAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYACIKLL 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 578 VKAG-------------------------------ASIDATSINNSTPLSRAIE-SCRLDTVKYLLDMGAKFQIENRKGH 625
Cdd:PHA02874 210 IDHGnhimnkckngftplhnaiihnrsaiellinnASINDQDIDGSTPLHHAINpPCDIDIIDILLYHKADISIKDNKGE 289
|
170 180 190
....*....|....*....|....*....|....*
gi 28316764 626 AAMDIAKAYADYriIDMIKEKLDN--LPKQADNQK 658
Cdd:PHA02874 290 NPIDTAFKYINK--DPVIKDIIANavLIKEADKLK 322
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
189-277 |
1.33e-14 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 69.76 E-value: 1.33e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 189 LMESSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLFAYNgdMGLIGMDGNTPLHFAAMGGFADCCK 268
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHA--DVNLKDNGRTALHYAARSGHLEIVK 78
|
....*....
gi 28316764 269 YIAQRGCDL 277
Cdd:pfam12796 79 LLLEKGADI 87
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
505-649 |
1.77e-14 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 76.24 E-value: 1.77e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 505 LASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQ-----QDIVELLVK 579
Cdd:PHA03100 15 VKNIKYIIMEDDLNDYSYKKPVLPLYLAKEARNIDVVKILLDNGADINSSTKNNSTPLHYLSNIKYnltdvKEIVKLLLE 94
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 28316764 580 AGASIDATSINNSTPLSRAI--ESCRLDTVKYLLDMGAKFQIENRKGHAAMdiaKAYADYRIID--MIKEKLDN 649
Cdd:PHA03100 95 YGANVNAPDNNGITPLLYAIskKSNSYSIVEYLLDNGANVNIKNSDGENLL---HLYLESNKIDlkILKLLIDK 165
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
512-586 |
1.38e-13 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 73.55 E-value: 1.38e-13
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28316764 512 IETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKAGASIDA 586
Cdd:PHA03100 179 LSYGVPINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIFKLLLNNGPSIKT 253
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
499-615 |
2.25e-13 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 72.78 E-value: 2.25e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 499 ITKAGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNID--VVKFLIEKGANVNATDN---FL-------------WT 560
Cdd:PHA03100 115 SKKSNSYSIVEYLLDNGANVNIKNSDGENLLHLYLESNKIDlkILKLLIDKGVDINAKNRvnyLLsygvpinikdvygFT 194
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 28316764 561 PLHFACHAGQQDIVELLVKAGASIDATSINNSTPLSRAIESCRLDTVKYLLDMGA 615
Cdd:PHA03100 195 PLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIFKLLLNNGP 249
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
527-578 |
3.83e-13 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 64.22 E-value: 3.83e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 28316764 527 TPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLV 578
Cdd:pfam13637 3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
512-616 |
4.39e-13 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 72.36 E-value: 4.39e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 512 IETGIPVDMKDNTYKTPL-MIACASGNIDVVKFLIEKGANVNATDNFLWTPLHfACHAGQQ---DIVELLVKAGASIDAT 587
Cdd:PHA03095 70 LEAGADVNAPERCGFTPLhLYLYNATTLDVIKLLIKAGADVNAKDKVGRTPLH-VYLSGFNinpKVIRLLLRKGADVNAL 148
|
90 100 110
....*....|....*....|....*....|.
gi 28316764 588 SINNSTPLSRAIES--CRLDTVKYLLDMGAK 616
Cdd:PHA03095 149 DLYGMTPLAVLLKSrnANVELLRLLIDAGAD 179
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
507-634 |
2.09e-12 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 69.99 E-value: 2.09e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 507 SLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKAGASIDA 586
Cdd:PHA02874 106 MIKTILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANV 185
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 28316764 587 TSINNSTPLSRAIESCRLDTVKYLLDMGAKFQIENRKGHAAMDIAKAY 634
Cdd:PHA02874 186 KDNNGESPLHNAAEYGDYACIKLLIDHGNHIMNKCKNGFTPLHNAIIH 233
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
512-644 |
1.41e-11 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 67.36 E-value: 1.41e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 512 IETGIPVDMKDNTYKTPLMIACASGNID--VVKFLIEKGANVNATDNFLWTPLH--FACHAGQQDIVELLVKAGASIDAT 587
Cdd:PHA03095 104 IKAGADVNAKDKVGRTPLHVYLSGFNINpkVIRLLLRKGADVNALDLYGMTPLAvlLKSRNANVELLRLLIDAGADVYAV 183
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 28316764 588 SINNSTPLSRAIESCRLDT--VKYLLDMGAKFQIENRKGHAAMDIAKAYADYRIIDMIK 644
Cdd:PHA03095 184 DDRFRSLLHHHLQSFKPRAriVRELIRAGCDPAATDMLGNTPLHSMATGSSCKRSLVLP 242
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
530-615 |
1.56e-11 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 67.36 E-value: 1.56e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 530 MIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQ---DIVELLVKAGASIDATSINNSTPLSRAIES-CRLD 605
Cdd:PHA03095 19 LLNASNVTVEEVRRLLAAGADVNFRGEYGKTPLHLYLHYSSEkvkDIVRLLLEAGADVNAPERCGFTPLHLYLYNaTTLD 98
|
90
....*....|
gi 28316764 606 TVKYLLDMGA 615
Cdd:PHA03095 99 VIKLLIKAGA 108
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
40-277 |
5.00e-11 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 65.82 E-value: 5.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 40 INFTEPIDGlSALHL---ASISNDTDMVSFLLKLGAHPDVQDHMGCTPTMRAAELGHELS-MEILAKAKADMTIVDNEGK 115
Cdd:PHA03095 40 VNFRGEYGK-TPLHLylhYSSEKVKDIVRLLLEAGADVNAPERCGFTPLHLYLYNATTLDvIKLLIKAGADVNAKDKVGR 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 116 GVLFYCiLPTKR-HYRCSLIALEHGADVNNI-TYEGKP--VFLRaceeAHDVKDMCLTFL-EKGANPNAINtSTGRTAL- 189
Cdd:PHA03095 119 TPLHVY-LSGFNiNPKVIRLLLRKGADVNALdLYGMTPlaVLLK----SRNANVELLRLLiDAGADVYAVD-DRFRSLLh 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 190 --MESSREGVlEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFF---DILKLLFAyNGDMGLIGMDGNTPLHFAAMGGFA 264
Cdd:PHA03095 193 hhLQSFKPRA-RIVRELIRAGCDPAATDMLGNTPLHSMATGSSCkrsLVLPLLIA-GISINARNRYGQTPLHYAAVFNNP 270
|
250
....*....|...
gi 28316764 265 DCCKYIAQRGCDL 277
Cdd:PHA03095 271 RACRRLIALGADI 283
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
512-615 |
6.54e-11 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 65.29 E-value: 6.54e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 512 IETGIPVDMKD-NTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKAGASIDATSIN 590
Cdd:PHA02878 154 LSYGADINMKDrHKGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKC 233
|
90 100
....*....|....*....|....*.
gi 28316764 591 NSTPLSRAIESCR-LDTVKYLLDMGA 615
Cdd:PHA02878 234 GNTPLHISVGYCKdYDILKLLLEHGV 259
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
52-143 |
1.05e-10 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 58.59 E-value: 1.05e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 52 LHLASISNDTDMVSFLLKLGAHPDVQDHMGCTPTMRAAELGH-ELSMEILAKAKADMtivDNEGKGVLFYCILptKRHYR 130
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHlEIVKLLLEHADVNL---KDNGRTALHYAAR--SGHLE 75
|
90
....*....|...
gi 28316764 131 CSLIALEHGADVN 143
Cdd:pfam12796 76 IVKLLLEKGADIN 88
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
136-287 |
1.25e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 64.21 E-value: 1.25e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 136 LEHGADVNNITYEGKPVFLRACE-EAHDV--------------------KDMCLTFLEKGANPNAINTSTgRTALMESSR 194
Cdd:PHA02874 55 IKHGADINHINTKIPHPLLTAIKiGAHDIikllidngvdtsilpipcieKDMIKTILDCGIDVNIKDAEL-KTFLHYAIK 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 195 EGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMDGNTPLHFAAMGGFADCCKYIAQRG 274
Cdd:PHA02874 134 KGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYACIKLLIDHG 213
|
170
....*....|...
gi 28316764 275 CDLKWKNLEHKTP 287
Cdd:PHA02874 214 NHIMNKCKNGFTP 226
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
161-618 |
1.57e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 64.70 E-value: 1.57e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 161 HDVKDMCLTFLEKGANPNAINTSTGRTAL--MESSREGV----LEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDIL 234
Cdd:PHA02876 115 HKLDEACIHILKEAISGNDIHYDKINESIeyMKLIKERIqqdeLLIAEMLLEGGADVNAKDIYCITPIHYAAERGNAKMV 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 235 KLLFAYNGDMGLIGMDGNTPLHFAAMGGFADCCKYIAQRGCDLKWKNL--------EHKTPRVVAKDGGFKAASKEIrra 306
Cdd:PHA02876 195 NLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKAIIDNRSNINKNDLsllkairnEDLETSLLLYDAGFSVNSIDD--- 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 307 ertaaklaktgAKNpNPLwalrlhDWSIEHETSLRNAFKFVDRGDGVVSKD---DFVVALEERQEYATsEQLLSVAqmhe 383
Cdd:PHA02876 272 -----------CKN-TPL------HHASQAPSLSRLVPKLLERGADVNAKNikgETPLYLMAKNGYDT-ENIRTLI---- 328
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 384 kSRGGGVNINEFFKGTKYLSKSYVlgsfgpkkkkrglgkkPRKGKFVLPLpictipenafprrpdggppyymIETYQNVS 463
Cdd:PHA02876 329 -MLGADVNAADRLYITPLHQASTL----------------DRNKDIVITL----------------------LELGANVN 369
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 464 dshrfNRDHPPEHPIQddsewYIDDPSRVFANISFITKAGDLASLKKAIETGIPVDMkdntyktplmiaCASGNIDVVKF 543
Cdd:PHA02876 370 -----ARDYCDKTPIH-----YAAVRNNVVIINTLLDYGADIEALSQKIGTALHFAL------------CGTNPYMSVKT 427
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 28316764 544 LIEKGANVNATDNFLWTPLHFACHAG-QQDIVELLVKAGASIDATSINNSTPLSRAIESCRLdtVKYLLDMGAKFQ 618
Cdd:PHA02876 428 LIDRGANVNSKNKDLSTPLHYACKKNcKLDVIEMLLDNGADVNAINIQNQYPLLIALEYHGI--VNILLHYGAELR 501
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
539-646 |
2.29e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 63.75 E-value: 2.29e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 539 DVVKFLIEKGANVNATD-NFLWTPLHFACHAGQQDIVELLVKAGASIDATSINNSTPLSRAIESCRLDTVKYLLDMGAKF 617
Cdd:PHA02878 148 EITKLLLSYGADINMKDrHKGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGAST 227
|
90 100 110
....*....|....*....|....*....|
gi 28316764 618 QIENRKGHAAMDIAKAYA-DYRIIDMIKEK 646
Cdd:PHA02878 228 DARDKCGNTPLHISVGYCkDYDILKLLLEH 257
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
19-243 |
5.12e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 62.38 E-value: 5.12e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 19 CVRNKDKKQIEKLTRLGYPELINFTEPidglsaLHLASISNDTDMVSFLLKLGAHPDVQDHMGCTPTMRAAELGHELS-- 96
Cdd:PHA03100 12 IIKVKNIKYIIMEDDLNDYSYKKPVLP------LYLAKEARNIDVVKILLDNGADINSSTKNNSTPLHYLSNIKYNLTdv 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 97 ---MEILAKAKADMTIVDNEGKGVLFYCILPTKRHYRCSLIALEHGADVNNITYEGKPVFLRACEEAHDVKDMCLTFLEK 173
Cdd:PHA03100 86 keiVKLLLEYGANVNAPDNNGITPLLYAISKKSNSYSIVEYLLDNGANVNIKNSDGENLLHLYLESNKIDLKILKLLIDK 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 174 GANPNAINT---------------STGRTALMESSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLF 238
Cdd:PHA03100 166 GVDINAKNRvnyllsygvpinikdVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIFKLLL 245
|
....*
gi 28316764 239 AYNGD 243
Cdd:PHA03100 246 NNGPS 250
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
518-611 |
5.18e-10 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 62.35 E-value: 5.18e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 518 VDMKDNTYKTPLMIACASGNIDVVKFlIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKAGASIDATSINNSTPLSR 597
Cdd:PHA03095 218 TDMLGNTPLHSMATGSSCKRSLVLPL-LIAGISINARNRYGQTPLHYAAVFNNPRACRRLIALGADINAVSSDGNTPLSL 296
|
90
....*....|....
gi 28316764 598 AIESCRLDTVKYLL 611
Cdd:PHA03095 297 MVRNNNGRAVRAAL 310
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
512-634 |
9.38e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 62.00 E-value: 9.38e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 512 IETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFA-CHAGQQDIVELLVKAGASIDATSIN 590
Cdd:PHA02876 362 LELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHFAlCGTNPYMSVKTLIDRGANVNSKNKD 441
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 28316764 591 NSTPLSRAIE-SCRLDTVKYLLDMGAKFQIENRKGHAAMDIAKAY 634
Cdd:PHA02876 442 LSTPLHYACKkNCKLDVIEMLLDNGADVNAINIQNQYPLLIALEY 486
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
537-656 |
1.42e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 61.13 E-value: 1.42e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 537 NIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKAGASIDATSINNSTPLSRAIESCRLDTVKYLLDMGAK 616
Cdd:PHA02874 103 EKDMIKTILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAY 182
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 28316764 617 FQIENRKGHAAMDIAKAYADYRIIDMIKEKLDNLPKQADN 656
Cdd:PHA02874 183 ANVKDNNGESPLHNAAEYGDYACIKLLIDHGNHIMNKCKN 222
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
500-634 |
2.96e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 60.00 E-value: 2.96e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 500 TKAGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVK 579
Cdd:PHA02875 110 TILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAMAKGDIAICKMLLD 189
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 580 AGASIDATSINNS-TPLSRAIESCRLDTVKYLLDMGAK----FQIENRKgHAAMDIAKAY 634
Cdd:PHA02875 190 SGANIDYFGKNGCvAALCYAIENNKIDIVRLFIKRGADcnimFMIEGEE-CTILDMICNM 248
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
510-631 |
5.54e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 59.69 E-value: 5.54e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 510 KAIETGIPVDMKDNTYKTPLMIACASG-NIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQ-QDIVELLVKAGASIDAT 587
Cdd:PHA02876 292 KLLERGADVNAKNIKGETPLYLMAKNGyDTENIRTLIMLGADVNAADRLYITPLHQASTLDRnKDIVITLLELGANVNAR 371
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 28316764 588 SINNSTPLSRAIESCRLDTVKYLLDMGAKFQIENRKGHAAMDIA 631
Cdd:PHA02876 372 DYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHFA 415
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
18-111 |
6.65e-09 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 53.58 E-value: 6.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 18 QCVRNKDKKQIEKLTRLGYPelINFTEPiDGLSALHLASISNDTDMVSFLLKlGAHPDVQDHmGCTPTMRAAELGHELSM 97
Cdd:pfam12796 3 LAAKNGNLELVKLLLENGAD--ANLQDK-NGRTALHLAAKNGHLEIVKLLLE-HADVNLKDN-GRTALHYAARSGHLEIV 77
|
90
....*....|....
gi 28316764 98 EILAKAKADMTIVD 111
Cdd:pfam12796 78 KLLLEKGADINVKD 91
|
|
| PHA02859 |
PHA02859 |
ankyrin repeat protein; Provisional |
485-648 |
8.37e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165195 [Multi-domain] Cd Length: 209 Bit Score: 56.37 E-value: 8.37e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 485 YIDDPSRVFAN-ISFITKAGDLASLKKAIETgipVDMKDNTYKTPLMiACASG---NIDVVKFLIEKGANVN-ATDNFLW 559
Cdd:PHA02859 13 FTDYLFYRYCNpLFYYVEKDDIEGVKKWIKF---VNDCNDLYETPIF-SCLEKdkvNVEILKFLIENGADVNfKTRDNNL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 560 TPLHFACHAGQ---QDIVELLVKAGASIDATSINNSTPLSRAIESC--RLDTVKYLLDMGAK-FQIENRKGHAAMDIAKA 633
Cdd:PHA02859 89 SALHHYLSFNKnvePEILKILIDSGSSITEEDEDGKNLLHMYMCNFnvRINVIKLLIDSGVSfLNKDFDNNNILYSYILF 168
|
170
....*....|....*.
gi 28316764 634 YADYRIID-MIKEKLD 648
Cdd:PHA02859 169 HSDKKIFDfLTSLGID 184
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
505-646 |
8.78e-09 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 57.66 E-value: 8.78e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 505 LASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKAGASI 584
Cdd:COG0666 1 LLLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADI 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28316764 585 DATSINNSTPLSRAIESCRLDTVKYLLDMGAKFQIENRKGHAAMDIAKAYADYRIIDMIKEK 646
Cdd:COG0666 81 NAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEA 142
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
502-646 |
1.05e-08 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 58.05 E-value: 1.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 502 AGDLASLKKAIET-GIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLV-- 578
Cdd:PHA02874 11 SGDIEAIEKIIKNkGNCINISVDETTTPLIDAIRSGDAKIVELFIKHGADINHINTKIPHPLLTAIKIGAHDIIKLLIdn 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 579 ---------------------KAGASIDATSINNSTPLSRAIESCRLDTVKYLLDMGAKFQIENRKGHAAMDIAKAYADY 637
Cdd:PHA02874 91 gvdtsilpipciekdmiktilDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFF 170
|
....*....
gi 28316764 638 RIIDMIKEK 646
Cdd:PHA02874 171 DIIKLLLEK 179
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
503-628 |
1.81e-08 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 57.31 E-value: 1.81e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 503 GDLASLKKAIETGIPVDmkDNTYK---TPLMIACASGNIDVVKFLIEKGAN--VNATDNFlwTPLHFACHAGQQDIVELL 577
Cdd:PHA02875 79 GDVKAVEELLDLGKFAD--DVFYKdgmTPLHLATILKKLDIMKLLIARGADpdIPNTDKF--SPLHLAVMMGDIKGIELL 154
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 28316764 578 VKAGASIDATSINNSTPLSRAIESCRLDTVKYLLDMGAKFQIENRKGHAAM 628
Cdd:PHA02875 155 IDHKACLDIEDCCGCTPLIIAMAKGDIAICKMLLDSGANIDYFGKNGCVAA 205
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
559-611 |
2.23e-08 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 50.74 E-value: 2.23e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 28316764 559 WTPLHFACHAGQQDIVELLVKAGASIDATSINNSTPLSRAIESCRLDTVKYLL 611
Cdd:pfam13637 2 LTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
544-598 |
3.47e-08 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 50.42 E-value: 3.47e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 28316764 544 LIEKG-ANVNATDNFLWTPLHFACHAGQQDIVELLVKAGASIDATSINNSTPLSRA 598
Cdd:pfam13857 1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
516-555 |
6.78e-08 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 50.88 E-value: 6.78e-08
10 20 30 40
....*....|....*....|....*....|....*....|
gi 28316764 516 IPVDMKDNTYkTPLMIACASGNIDVVKFLIEKGANVNATD 555
Cdd:pfam12796 53 ADVNLKDNGR-TALHYAARSGHLEIVKLLLEKGADINVKD 91
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
508-599 |
8.59e-08 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 55.27 E-value: 8.59e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 508 LKKAIETGIPVDMKDNTYKTPLMIACAS-GNIDVVKFLIEKGANVNATDNFL-WTPLHFACHAgqQDIVELLVKAGASID 585
Cdd:PHA02878 217 VHILLENGASTDARDKCGNTPLHISVGYcKDYDILKLLLEHGVDVNAKSYILgLTALHSSIKS--ERKLKLLLEYGADIN 294
|
90
....*....|....
gi 28316764 586 ATSINNSTPLSRAI 599
Cdd:PHA02878 295 SLNSYKLTPLSSAV 308
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
502-577 |
1.42e-07 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 54.90 E-value: 1.42e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 28316764 502 AGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELL 577
Cdd:PTZ00322 92 SGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLL 167
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
20-185 |
1.64e-07 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 54.23 E-value: 1.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 20 VRNKDKKQIEKLTRLGypELINFTEPIDGLSALHLASISNDTDMVSFLLKLGAHPDVQDHMGCTPTMRAAELGHELSMEI 99
Cdd:PHA02875 76 VEEGDVKAVEELLDLG--KFADDVFYKDGMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIEL 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 100 LAKAKADMTIVDNEGKGVLFYCIlpTKRHYRCSLIALEHGAdvnNITYEGK-PVFLRACEEAHDVK-DMCLTFLEKGANP 177
Cdd:PHA02875 154 LIDHKACLDIEDCCGCTPLIIAM--AKGDIAICKMLLDSGA---NIDYFGKnGCVAALCYAIENNKiDIVRLFIKRGADC 228
|
....*...
gi 28316764 178 NAINTSTG 185
Cdd:PHA02875 229 NIMFMIEG 236
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
516-565 |
2.23e-07 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 48.11 E-value: 2.23e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 28316764 516 IPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFA 565
Cdd:pfam13857 7 IDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
527-556 |
2.98e-07 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 47.28 E-value: 2.98e-07
10 20 30
....*....|....*....|....*....|.
gi 28316764 527 TPLMIACAS-GNIDVVKFLIEKGANVNATDN 556
Cdd:pfam00023 4 TPLHLAAGRrGNLEIVKLLLSKGADVNARDK 34
|
|
| TRPV5-6 |
cd22192 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ... |
526-595 |
3.19e-07 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.
Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 53.86 E-value: 3.19e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 526 KTPLMIACASGNIDVVKFLIEKGANVN---AT--------DNFLW---TPLHFACHAGQQDIVELLVKAGASIDATSINN 591
Cdd:cd22192 90 ETALHIAVVNQNLNLVRELIARGADVVsprATgtffrpgpKNLIYygeHPLSFAACVGNEEIVRLLIEHGADIRAQDSLG 169
|
....
gi 28316764 592 STPL 595
Cdd:cd22192 170 NTVL 173
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
526-553 |
9.59e-07 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 45.66 E-value: 9.59e-07
10 20
....*....|....*....|....*...
gi 28316764 526 KTPLMIACASGNIDVVKFLIEKGANVNA 553
Cdd:smart00248 3 RTPLHLAAENGNLEVVKLLLDKGADINA 30
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
534-611 |
1.12e-06 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 52.21 E-value: 1.12e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 28316764 534 ASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKAGASIDATSINNSTPLSRAIESCRLDTVKYLL 611
Cdd:PTZ00322 91 ASGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLS 168
|
|
| PHA02884 |
PHA02884 |
ankyrin repeat protein; Provisional |
486-602 |
1.30e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165212 [Multi-domain] Cd Length: 300 Bit Score: 51.14 E-value: 1.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 486 IDDPSRVFANISFITKAGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFL-WTPLHF 564
Cdd:PHA02884 31 ICIANILYSSIKFHYTDIIDAILKLGADPEAPFPLSENSKTNPLIYAIDCDNDDAAKLLIRYGADVNRYAEEAkITPLYI 110
|
90 100 110
....*....|....*....|....*....|....*...
gi 28316764 565 ACHAGQQDIVELLVKAGASIDATSINNSTPLSRAIESC 602
Cdd:PHA02884 111 SVLHGCLKCLEILLSYGADINIQTNDMVTPIELALMIC 148
|
|
| PHA02798 |
PHA02798 |
ankyrin-like protein; Provisional |
508-660 |
1.61e-06 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222931 [Multi-domain] Cd Length: 489 Bit Score: 51.37 E-value: 1.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 508 LKKAIETGIPVDMKDNTYKTPLM-----IACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAG---QQDIVELLVK 579
Cdd:PHA02798 54 VKLFINLGANVNGLDNEYSTPLCtilsnIKDYKHMLDIVKILIENGADINKKNSDGETPLYCLLSNGyinNLEILLFMIE 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 580 AGASIDATSINNSTPLSRAIES---CRLDTVKYLLDMGAKF-QIENRKGHAAMDIAKAYADYRI-IDMIKEKLDN--LPK 652
Cdd:PHA02798 134 NGADTTLLDKDGFTMLQVYLQSnhhIDIEIIKLLLEKGVDInTHNNKEKYDTLHCYFKYNIDRIdADILKLFVDNgfIIN 213
|
....*...
gi 28316764 653 QADNQKMK 660
Cdd:PHA02798 214 KENKSHKK 221
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
46-287 |
1.92e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 51.22 E-value: 1.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 46 IDGLSALHLASISNDTDMVSFLLKLGAHPDVQDhMGCTPTMRAAELGHELsmeILAKAKADMTIVDNEGKGVLFYCIlPT 125
Cdd:PHA02876 209 LDDLSVLECAVDSKNIDTIKAIIDNRSNINKND-LSLLKAIRNEDLETSL---LLYDAGFSVNSIDDCKNTPLHHAS-QA 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 126 KRHYRCSLIALEHGADVNNITYEGK-PVFLRAcEEAHDVKDMcLTFLEKGANPNAINTSTGRTALMESSREGVLEIVRGI 204
Cdd:PHA02876 284 PSLSRLVPKLLERGADVNAKNIKGEtPLYLMA-KNGYDTENI-RTLIMLGADVNAADRLYITPLHQASTLDRNKDIVITL 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 205 LERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMDGNTPLHFAAMGGFA-DCCKYIAQRGCDLKWKNLE 283
Cdd:PHA02876 362 LELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHFALCGTNPyMSVKTLIDRGANVNSKNKD 441
|
....
gi 28316764 284 HKTP 287
Cdd:PHA02876 442 LSTP 445
|
|
| Ank_3 |
pfam13606 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
525-553 |
1.92e-06 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.
Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 44.94 E-value: 1.92e-06
10 20
....*....|....*....|....*....
gi 28316764 525 YKTPLMIACASGNIDVVKFLIEKGANVNA 553
Cdd:pfam13606 2 GNTPLHLAARNGRLEIVKLLLENGADINA 30
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
1-181 |
4.93e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 49.88 E-value: 4.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 1 MALADKRLENLQIYRVLQCVRNKDKKQIEKLTRL--GYPELINFTEPIDGLSALHLASISNDTDMVSFLLKLGAHPDVQD 78
Cdd:PHA02878 119 IILTNRYKNIQTIDLVYIDKKSKDDIIEAEITKLllSYGADINMKDRHKGNTALHYATENKDQRLTELLLSYGANVNIPD 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 79 HMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGVLFYCILPTKrHYRCSLIALEHGADVNNITYEGKPVFLRACE 158
Cdd:PHA02878 199 KTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHISVGYCK-DYDILKLLLEHGVDVNAKSYILGLTALHSSI 277
|
170 180
....*....|....*....|...
gi 28316764 159 EAHDVKDMcltFLEKGANPNAIN 181
Cdd:PHA02878 278 KSERKLKL---LLEYGADINSLN 297
|
|
| PLN03192 |
PLN03192 |
Voltage-dependent potassium channel; Provisional |
487-765 |
5.86e-06 |
|
Voltage-dependent potassium channel; Provisional
Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 49.87 E-value: 5.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 487 DDPSRVFANISFITKAGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFAC 566
Cdd:PLN03192 520 HDDPNMASNLLTVASTGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAI 599
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 567 HAGQQDIVELLVKAGASIDATSINNStpLSRAIESCRLDTVKYLLDMGAKFQIENRKGHAAMDIAKAyadyriidmikek 646
Cdd:PLN03192 600 SAKHHKIFRILYHFASISDPHAAGDL--LCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMA------------- 664
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 647 ldnlPKQADNQKMkgklpkLKTEGTDVKKE--EETLSSIYTVPAITEEKKVHRDSVVylNSLITSGFTKKVDITFIPKRI 724
Cdd:PLN03192 665 ----EDHVDMVRL------LIMNGADVDKAntDDDFSPTELRELLQKRELGHSITIV--DSVPADEPDLGRDGGSRPGRL 732
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 28316764 725 WSPEATTAELIR------KRELRRERFTYE----VDFEDFMMPFQKNITEK 765
Cdd:PLN03192 733 QGTSSDNQCRPRvsiykgHPLLRNERCCNEagklINLPPSLEELKAIAGEK 783
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
501-545 |
6.02e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 44.19 E-value: 6.02e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 28316764 501 KAGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLI 545
Cdd:pfam13637 10 ASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
218-269 |
1.08e-05 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 43.42 E-value: 1.08e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 28316764 218 RHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMDGNTPLHFAAMGGFADCCKY 269
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKL 52
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
169-281 |
1.14e-05 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 48.51 E-value: 1.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 169 TFLEKGANPNaINTSTGRTALMESSREG-----VLEIVRGILERGGEVNAYDNDRHHAAHFAA--KGGFFDILKLLFAYN 241
Cdd:PHA03100 53 ILLDNGADIN-SSTKNNSTPLHYLSNIKynltdVKEIVKLLLEYGANVNAPDNNGITPLLYAIskKSNSYSIVEYLLDNG 131
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 28316764 242 GDMGLIGMDGNTPLHFAAMGGFAD--CCKYIAQRGCDLKWKN 281
Cdd:PHA03100 132 ANVNIKNSDGENLLHLYLESNKIDlkILKLLIDKGVDINAKN 173
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
559-587 |
1.48e-05 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 42.28 E-value: 1.48e-05
10 20 30
....*....|....*....|....*....|
gi 28316764 559 WTPLHFAC-HAGQQDIVELLVKAGASIDAT 587
Cdd:pfam00023 3 NTPLHLAAgRRGNLEIVKLLLSKGADVNAR 32
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
105-286 |
2.03e-05 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 47.95 E-value: 2.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 105 ADMTIVD-NEGKGVLFYciLPTKRHYRCSLIALEHGADVNNITYEGKPVFLRACEeaHDVKDMCLTFLEKGANPNAINtS 183
Cdd:PHA02878 158 ADINMKDrHKGNTALHY--ATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVK--HYNKPIVHILLENGASTDARD-K 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 184 TGRTAL-MESSREGVLEIVRGILERGGEVNAYDNDRHHAA-HFAAKGGffDILKLLFAYNGDMGLIGMDGNTPLHFAAMG 261
Cdd:PHA02878 233 CGNTPLhISVGYCKDYDILKLLLEHGVDVNAKSYILGLTAlHSSIKSE--RKLKLLLEYGADINSLNSYKLTPLSSAVKQ 310
|
170 180
....*....|....*....|....*.
gi 28316764 262 GFA-DCCKYIAQRGCDLKWKNLEHKT 286
Cdd:PHA02878 311 YLCiNIGRILISNICLLKRIKPDIKN 336
|
|
| trp |
TIGR00870 |
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ... |
527-623 |
2.59e-05 |
|
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ Channel (TRP-CC) Family (TC. 1.A.4)The TRP-CC family has also been called the store-operated calcium channel (SOC) family. The prototypical members include the Drosophila retinal proteinsTRP and TRPL (Montell and Rubin, 1989; Hardie and Minke, 1993). SOC members of the family mediate the entry of extracellular Ca2+ into cells in responseto depletion of intracellular Ca2+ stores (Clapham, 1996) and agonist stimulated production of inositol-1,4,5 trisphosphate (IP3). One member of the TRP-CCfamily, mammalian Htrp3, has been shown to form a tight complex with the IP3 receptor (TC #1.A.3.2.1). This interaction is apparently required for IP3 tostimulate Ca2+ release via Htrp3. The vanilloid receptor subtype 1 (VR1), which is the receptor for capsaicin (the ?hot? ingredient in chili peppers) and servesas a heat-activated ion channel in the pain pathway (Caterina et al., 1997), is also a member of this family. The stretch-inhibitable non-selective cation channel(SIC) is identical to the vanilloid receptor throughout all of its first 700 residues, but it exhibits a different sequence in its last 100 residues. VR1 and SICtransport monovalent cations as well as Ca2+. VR1 is about 10x more permeable to Ca2+ than to monovalent ions. Ca2+ overload probably causes cell deathafter chronic exposure to capsaicin. (McCleskey and Gold, 1999). [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 47.77 E-value: 2.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 527 TPLMIACASGNIDVVKFLIEKGANVNAT---DNFLWT-----------PLHFACHAGQQDIVELLVKAGASIDAT-SINN 591
Cdd:TIGR00870 130 TALHLAAHRQNYEIVKLLLERGASVPARacgDFFVKSqgvdsfyhgesPLNAAACLGSPSIVALLSEDPADILTAdSLGN 209
|
90 100 110
....*....|....*....|....*....|..
gi 28316764 592 stplsraiescrldTVKYLLDMGAKFQIENRK 623
Cdd:TIGR00870 210 --------------TLLHLLVMENEFKAEYEE 227
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
48-94 |
2.76e-05 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 42.26 E-value: 2.76e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 28316764 48 GLSALHLASISNDTDMVSFLLKLGAHPDVQDHMGCTPTMRAAELGHE 94
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNV 47
|
|
| PLN03192 |
PLN03192 |
Voltage-dependent potassium channel; Provisional |
88-242 |
3.04e-05 |
|
Voltage-dependent potassium channel; Provisional
Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 47.56 E-value: 3.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 88 AAELGHELSMEILAKAKADMTIVDNEGKGVLFycILPTKRHYRCSLIALEHGADVNNITYEGKPVFLRACEEAHDVKDMC 167
Cdd:PLN03192 532 VASTGNAALLEELLKAKLDPDIGDSKGRTPLH--IAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAISAKHHKIFRI 609
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28316764 168 LTFLEKGANPNaintsTGRTALMESSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLfAYNG 242
Cdd:PLN03192 610 LYHFASISDPH-----AAGDLLCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMAEDHVDMVRLL-IMNG 678
|
|
| PHA02798 |
PHA02798 |
ankyrin-like protein; Provisional |
538-648 |
3.17e-05 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222931 [Multi-domain] Cd Length: 489 Bit Score: 47.14 E-value: 3.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 538 IDVVKFLIEKGANVNATDNFLWTPL-----HFACHAGQQDIVELLVKAGASIDATSINNSTPL-----SRAIEScrLDTV 607
Cdd:PHA02798 51 TDIVKLFINLGANVNGLDNEYSTPLctilsNIKDYKHMLDIVKILIENGADINKKNSDGETPLycllsNGYINN--LEIL 128
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 28316764 608 KYLLDMGAKFQIENRKGHAAMDIAKAYADYRIIDMIKEKLD 648
Cdd:PHA02798 129 LFMIENGADTTLLDKDGFTMLQVYLQSNHHIDIEIIKLLLE 169
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
204-258 |
5.13e-05 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 41.56 E-value: 5.13e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 28316764 204 ILERGGE-VNAYDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMDGNTPLHFA 258
Cdd:pfam13857 1 LLEHGPIdLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| PHA02716 |
PHA02716 |
CPXV016; CPX019; EVM010; Provisional |
497-652 |
5.29e-05 |
|
CPXV016; CPX019; EVM010; Provisional
Pssm-ID: 165089 [Multi-domain] Cd Length: 764 Bit Score: 46.83 E-value: 5.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 497 SFITKAG--DLASLKKAIETGIPVDMKDNTYKTPL--MIACASGNIDVVKFLIEKGANVNATDNFLWTPLHfaCHAGQQD 572
Cdd:PHA02716 287 SYITLARniDISVVYSFLQPGVKLHYKDSAGRTCLhqYILRHNISTDIIKLLHEYGNDLNEPDNIGNTVLH--TYLSMLS 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 573 IVELLvkagasidATSINNSTplsraiescRLDTVKYLLDMGAKFQIENRKGHAAMD----IAKAYADYRIID-MIKEKL 647
Cdd:PHA02716 365 VVNIL--------DPETDNDI---------RLDVIQCLISLGADITAVNCLGYTPLTsyicTAQNYMYYDIIDcLISDKV 427
|
....*
gi 28316764 648 DNLPK 652
Cdd:PHA02716 428 LNMVK 432
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
47-79 |
2.18e-04 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 39.19 E-value: 2.18e-04
10 20 30
....*....|....*....|....*....|....
gi 28316764 47 DGLSALHLASIS-NDTDMVSFLLKLGAHPDVQDH 79
Cdd:pfam00023 1 DGNTPLHLAAGRrGNLEIVKLLLSKGADVNARDK 34
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
528-659 |
3.25e-04 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 44.10 E-value: 3.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 528 PLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFAC-HAGQQDIVELL---VKAGASIDATSIN------------- 590
Cdd:PHA02878 40 PLHQAVEARNLDVVKSLLTRGHNVNQPDHRDLTPLHIICkEPNKLGMKEMIrsiNKCSVFYTLVAIKdafnnrnveifki 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 591 ---NSTPLSRAIESCRLDT-----------VKYLLDMGAKFQIENR-KGHAAMDIAKAYADYRIID--MIKEKLDNLPKQ 653
Cdd:PHA02878 120 iltNRYKNIQTIDLVYIDKkskddiieaeiTKLLLSYGADINMKDRhKGNTALHYATENKDQRLTEllLSYGANVNIPDK 199
|
....*.
gi 28316764 654 ADNQKM 659
Cdd:PHA02878 200 TNNSPL 205
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
559-586 |
3.62e-04 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 38.34 E-value: 3.62e-04
10 20
....*....|....*....|....*...
gi 28316764 559 WTPLHFACHAGQQDIVELLVKAGASIDA 586
Cdd:smart00248 3 RTPLHLAAENGNLEVVKLLLDKGADINA 30
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
53-260 |
4.98e-04 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 43.47 E-value: 4.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 53 HLASISNDTDMVSFLLKLGAHPDVQDHMGCTPTmrAAELG-HELSMEI---LAKAKADMTIVDNEGKGvlfycilptkrh 128
Cdd:PHA03095 124 YLSGFNINPKVIRLLLRKGADVNALDLYGMTPL--AVLLKsRNANVELlrlLIDAGADVYAVDDRFRS------------ 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 129 yrcsliALEHGADVnnityegkpvflraceeAHDVKDMCLTFLEKGANPNAINTStGRTAL----MESSREGVLeiVRGI 204
Cdd:PHA03095 190 ------LLHHHLQS-----------------FKPRARIVRELIRAGCDPAATDML-GNTPLhsmaTGSSCKRSL--VLPL 243
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 28316764 205 LERGGEVNAYDNDRHHAAHFAAKGG---FFDilKLLfAYNGDMGLIGMDGNTPLHFAAM 260
Cdd:PHA03095 244 LIAGISINARNRYGQTPLHYAAVFNnprACR--RLI-ALGADINAVSSDGNTPLSLMVR 299
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
136-258 |
5.51e-04 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 43.03 E-value: 5.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 136 LEHGADVNNITYEGKpVFLRACEEAHDVKDMClTFLEKGANPNaINTSTGRTALMESSREGVLEIVRGILERGGEVNAYD 215
Cdd:PHA02874 111 LDCGIDVNIKDAELK-TFLHYAIKKGDLESIK-MLFEYGADVN-IEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKD 187
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 28316764 216 NDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMDGNTPLHFA 258
Cdd:PHA02874 188 NNGESPLHNAAEYGDYACIKLLIDHGNHIMNKCKNGFTPLHNA 230
|
|
| TRPV |
cd21882 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily ... |
520-658 |
6.17e-04 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily (TRPV), named after the vanilloid receptor 1 (TRPV1), consists of six members: four thermo-sensing channels (TRPV1, TRPV2, TRPV3, and TRPV4) and two Ca2+ selective channels (TRPV5 and TRPV6). The calcium-selective channels TRPV5 and TRPV6 can be heterotetramers and are important for general Ca2+ homeostasis. All four channels within the TRPV1-4 group show temperature-invoked currents when expressed in heterologous cell systems, ranging from activation at ~25C for TRPV4 to ~52C for TRPV2. The structure of TRPV shows the typical topology features of all Transient Receptor Potential (TRP) ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains. The TRP family consists of membrane proteins that function as ion channels that communicate between the cell and its environment, by a vast array of physical or chemical stimuli, including radiation (in the form of temperature, infrared ,or light) and pressure (osmotic or mechanical). TRP channels are formed by a tetrameric complex of channel subunits. Based on sequence identity, the mammalian TRP channel family is classified into six subfamilies, with significant sequence similarity within the transmembrane domains, but very low similarity in their N- and C-terminal cytoplasmic regions. The six subfamilies are named based on their first member: TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPA (ankyrin), TRPML (mucolipin), and TRPP (polycystic).
Pssm-ID: 411975 [Multi-domain] Cd Length: 600 Bit Score: 43.33 E-value: 6.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 520 MKDNTYK--TPLMIACASGNIDVVKFLIEKGANVNATDN-------------FLWTPLHFACHAGQQDIVELLVKAGASI 584
Cdd:cd21882 66 CTDEFYQgqTALHIAIENRNLNLVRLLVENGADVSARATgrffrkspgnlfyFGELPLSLAACTNQEEIVRLLLENGAQP 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 585 DATSINNS---TPL-------SRAIESCRLDTVKY--LLDMGAKF-------QIENRKGHAAMDIAKAYADYRIIDMIKE 645
Cdd:cd21882 146 AALEAQDSlgnTVLhalvlqaDNTPENSAFVCQMYnlLLSYGAHLdptqqleEIPNHQGLTPLKLAAVEGKIVMFQHILQ 225
|
170
....*....|...
gi 28316764 646 KLDNLPKQADNQK 658
Cdd:cd21882 226 REFSGPYQPLSRK 238
|
|
| PHA02946 |
PHA02946 |
ankyin-like protein; Provisional |
10-130 |
6.52e-04 |
|
ankyin-like protein; Provisional
Pssm-ID: 165256 [Multi-domain] Cd Length: 446 Bit Score: 43.12 E-value: 6.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 10 NLQIYRVLQCVRNKDKKQIEKLTRLGYPEliNFTEPiDGLSALHLASISNDTDMVSFLLKLGAHPDVQDHMGCTPTMRAA 89
Cdd:PHA02946 37 NYHILHAYCGIKGLDERFVEELLHRGYSP--NETDD-DGNYPLHIASKINNNRIVAMLLTHGADPNACDKQHKTPLYYLS 113
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 28316764 90 ----ELGHELSMEILAKAKADMTiVDNEGKGVLFYCILPTKRHYR 130
Cdd:PHA02946 114 gtddEVIERINLLVQYGAKINNS-VDEEGCGPLLACTDPSERVFK 157
|
|
| Ank_3 |
pfam13606 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
47-76 |
1.16e-03 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.
Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 36.85 E-value: 1.16e-03
10 20 30
....*....|....*....|....*....|
gi 28316764 47 DGLSALHLASISNDTDMVSFLLKLGAHPDV 76
Cdd:pfam13606 1 DGNTPLHLAARNGRLEIVKLLLENGADINA 30
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
250-277 |
2.04e-03 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 36.03 E-value: 2.04e-03
10 20
....*....|....*....|....*...
gi 28316764 250 DGNTPLHFAAMGGFADCCKYIAQRGCDL 277
Cdd:smart00248 1 DGRTPLHLAAENGNLEVVKLLLDKGADI 28
|
|
| Ank_3 |
pfam13606 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
250-277 |
2.77e-03 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.
Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 35.70 E-value: 2.77e-03
10 20
....*....|....*....|....*...
gi 28316764 250 DGNTPLHFAAMGGFADCCKYIAQRGCDL 277
Cdd:pfam13606 1 DGNTPLHLAARNGRLEIVKLLLENGADI 28
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
201-265 |
2.87e-03 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 41.04 E-value: 2.87e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28316764 201 VRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMDGNTPLHFAAMGGFAD 265
Cdd:PTZ00322 98 ARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFRE 162
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
185-237 |
2.90e-03 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 36.48 E-value: 2.90e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 28316764 185 GRTALMESSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLL 237
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLL 53
|
|
| PHA02989 |
PHA02989 |
ankyrin repeat protein; Provisional |
485-625 |
3.08e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222954 [Multi-domain] Cd Length: 494 Bit Score: 40.88 E-value: 3.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 485 YIDDPSRVFANISFITKAGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNI---DVVKFLIEKGANVNATDNFL-WT 560
Cdd:PHA02989 68 YIETPLCAVLRNREITSNKIKKIVKLLLKFGADINLKTFNGVSPIVCFIYNSNInncDMLRFLLSKGINVNDVKNSRgYN 147
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28316764 561 PLH--FACHAGQQDIVELLVKAGASI-DATSINNSTP----LSRAIESCRLDTVKYLLDMGAKFQiENRKGH 625
Cdd:PHA02989 148 LLHmyLESFSVKKDVIKILLSFGVNLfEKTSLYGLTPmniyLRNDIDVISIKVIKYLIKKGVNIE-TNNNGS 218
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
171-258 |
3.38e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 40.63 E-value: 3.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 171 LEKGANPNAINTSTGRTALMESSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMD 250
Cdd:PHA02878 154 LSYGADINMKDRHKGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKC 233
|
....*...
gi 28316764 251 GNTPLHFA 258
Cdd:PHA02878 234 GNTPLHIS 241
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
503-643 |
3.49e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 40.74 E-value: 3.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 503 GDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKAGA 582
Cdd:PHA02875 13 GELDIARRLLDIGINPNFEIYDGISPIKLAMKFRDSEAIKLLMKHGAIPDVKYPDIESELHDAVEEGDVKAVEELLDLGK 92
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28316764 583 SI-DATSINNSTPLSRAIESCRLDTVKYLLDMGAKFQIENRKGHAAMDIAKAYADYRIIDMI 643
Cdd:PHA02875 93 FAdDVFYKDGMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELL 154
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
512-628 |
3.82e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 40.82 E-value: 3.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 512 IETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVN--ATDNFlwTPLHFACHAGQQDIVE-------------- 575
Cdd:PHA02876 165 LEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNiiALDDL--SVLECAVDSKNIDTIKaiidnrsninkndl 242
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 28316764 576 ---------------LLVKAGASIDATSINNSTPLSRAIESCRLDT-VKYLLDMGAKFQIENRKGHAAM 628
Cdd:PHA02876 243 sllkairnedletslLLYDAGFSVNSIDDCKNTPLHHASQAPSLSRlVPKLLERGADVNAKNIKGETPL 311
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
250-281 |
3.96e-03 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 35.34 E-value: 3.96e-03
10 20 30
....*....|....*....|....*....|...
gi 28316764 250 DGNTPLHFAA-MGGFADCCKYIAQRGCDLKWKN 281
Cdd:pfam00023 1 DGNTPLHLAAgRRGNLEIVKLLLSKGADVNARD 33
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
171-240 |
6.74e-03 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 39.88 E-value: 6.74e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28316764 171 LEKGANPNAINTStGRTALMESSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLFAY 240
Cdd:PTZ00322 102 LTGGADPNCRDYD-GRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSRH 170
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
47-76 |
9.65e-03 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 34.49 E-value: 9.65e-03
10 20 30
....*....|....*....|....*....|
gi 28316764 47 DGLSALHLASISNDTDMVSFLLKLGAHPDV 76
Cdd:smart00248 1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
|
|
| |
