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Conserved domains on  [gi|110625972|ref|NP_766294|]
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endosome/lysosome-associated apoptosis and autophagy regulator family member 2 isoform 1 precursor [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ephrin_rec_like super family cl06646
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 401-431 1.52e-04

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


The actual alignment was detected with superfamily member pfam07699:

Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 40.41  E-value: 1.52e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 110625972   401 FYNNGSSSCHPCPPGTFSD--GTKECKSCPAGT 431
Cdd:pfam07699    3 YSNTGLEPCIPCPRGTYQPeeGQLSCLACPLGT 35
Ephrin_rec_like super family cl06646
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 286-320 3.85e-03

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


The actual alignment was detected with superfamily member pfam07699:

Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 36.17  E-value: 3.85e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 110625972   286 TSECFPCKPGTFSNKPGSFNCQMCPRNTYSEK-GAK 320
Cdd:pfam07699    8 LEPCIPCPRGTYQPEEGQLSCLACPLGTTTDSpGAT 43
 
Name Accession Description Interval E-value
Ephrin_rec_like pfam07699
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 401-431 1.52e-04

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 40.41  E-value: 1.52e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 110625972   401 FYNNGSSSCHPCPPGTFSD--GTKECKSCPAGT 431
Cdd:pfam07699    3 YSNTGLEPCIPCPRGTYQPeeGQLSCLACPLGT 35
Ephrin_rec_like pfam07699
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 286-320 3.85e-03

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 36.17  E-value: 3.85e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 110625972   286 TSECFPCKPGTFSNKPGSFNCQMCPRNTYSEK-GAK 320
Cdd:pfam07699    8 LEPCIPCPRGTYQPEEGQLSCLACPLGTTTDSpGAT 43
 
Name Accession Description Interval E-value
Ephrin_rec_like pfam07699
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 401-431 1.52e-04

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 40.41  E-value: 1.52e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 110625972   401 FYNNGSSSCHPCPPGTFSD--GTKECKSCPAGT 431
Cdd:pfam07699    3 YSNTGLEPCIPCPRGTYQPeeGQLSCLACPLGT 35
Ephrin_rec_like pfam07699
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 286-320 3.85e-03

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 36.17  E-value: 3.85e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 110625972   286 TSECFPCKPGTFSNKPGSFNCQMCPRNTYSEK-GAK 320
Cdd:pfam07699    8 LEPCIPCPRGTYQPEEGQLSCLACPLGTTTDSpGAT 43
Ephrin_rec_like pfam07699
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 295-325 7.75e-03

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 35.40  E-value: 7.75e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 110625972   295 GTFSNKpGSFNCQMCPRNTY-SEKGAKECIRC 325
Cdd:pfam07699    1 GTYSNT-GLEPCIPCPRGTYqPEEGQLSCLAC 31
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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