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Conserved domains on  [gi|26986537|ref|NP_758458|]
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diphthamide biosynthesis protein 3 isoform 1 [Mus musculus]

Protein Classification

CSL-type zinc finger protein( domain architecture ID 10525158)

CSL-type zinc finger protein similar to diphthamide biosynthesis protein 3 (DPH3) that is required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-CSL pfam05207
CSL zinc finger; This is a zinc binding motif which contains four cysteine residues which ...
 6-60 6.25e-24

CSL zinc finger; This is a zinc binding motif which contains four cysteine residues which chelate zinc. This domain is often found associated with a pfam00226 domain. This domain is named after the conserved motif of the final cysteine.


:

Pssm-ID: 398744  Cd Length: 55  Bit Score: 84.98  E-value: 6.25e-24
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 26986537    6 DEVEIEDFQYDEDSETYFYPCPCGDNFAITKEDLENGEDVATCPSCSLIIKVIYD 60
Cdd:pfam05207  1 DEVELEDFEFDEEEESYYYPCRCGDEFEITEEDLEEGEVVVQCPSCSLWIKVIYD 55
 
Name Accession Description Interval E-value
zf-CSL pfam05207
CSL zinc finger; This is a zinc binding motif which contains four cysteine residues which ...
 6-60 6.25e-24

CSL zinc finger; This is a zinc binding motif which contains four cysteine residues which chelate zinc. This domain is often found associated with a pfam00226 domain. This domain is named after the conserved motif of the final cysteine.


Pssm-ID: 398744  Cd Length: 55  Bit Score: 84.98  E-value: 6.25e-24
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 26986537    6 DEVEIEDFQYDEDSETYFYPCPCGDNFAITKEDLENGEDVATCPSCSLIIKVIYD 60
Cdd:pfam05207  1 DEVELEDFEFDEEEESYYYPCRCGDEFEITEEDLEEGEVVVQCPSCSLWIKVIYD 55
COG5216 COG5216
Uncharacterized conserved protein [Function unknown];
4-65 3.35e-23

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 227541  Cd Length: 67  Bit Score: 83.74  E-value: 3.35e-23
                       10        20        30        40        50        60
               ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 26986537  4 FHDEVEIEDFQYDEDSETYFYPCPCGDNFAITKEDLENGEDVATCPSCSLIIKVIYDKDQFM 65
Cdd:COG5216  3 FYDEIEIEDFTFSREEKTFTYPCPCGDRFEISLEDLRNGEVVARCPSCSLIVCVVYDAEDLE 64
 
Name Accession Description Interval E-value
zf-CSL pfam05207
CSL zinc finger; This is a zinc binding motif which contains four cysteine residues which ...
 6-60 6.25e-24

CSL zinc finger; This is a zinc binding motif which contains four cysteine residues which chelate zinc. This domain is often found associated with a pfam00226 domain. This domain is named after the conserved motif of the final cysteine.


Pssm-ID: 398744  Cd Length: 55  Bit Score: 84.98  E-value: 6.25e-24
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 26986537    6 DEVEIEDFQYDEDSETYFYPCPCGDNFAITKEDLENGEDVATCPSCSLIIKVIYD 60
Cdd:pfam05207  1 DEVELEDFEFDEEEESYYYPCRCGDEFEITEEDLEEGEVVVQCPSCSLWIKVIYD 55
COG5216 COG5216
Uncharacterized conserved protein [Function unknown];
4-65 3.35e-23

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 227541  Cd Length: 67  Bit Score: 83.74  E-value: 3.35e-23
                       10        20        30        40        50        60
               ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 26986537  4 FHDEVEIEDFQYDEDSETYFYPCPCGDNFAITKEDLENGEDVATCPSCSLIIKVIYDKDQFM 65
Cdd:COG5216  3 FYDEIEIEDFTFSREEKTFTYPCPCGDRFEISLEDLRNGEVVARCPSCSLIVCVVYDAEDLE 64
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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