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Conserved domains on  [gi|26787986|ref|NP_751915|]
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interleukin-15 isoform 2 preproprotein [Homo sapiens]

Protein Classification

IL15 domain-containing protein( domain architecture ID 10492994)

IL15 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IL15 pfam02372
Interleukin 15; Interleukin-15 (IL-15) is a cytokine that possesses a variety of biological ...
 10-127 2.67e-43

Interleukin 15; Interleukin-15 (IL-15) is a cytokine that possesses a variety of biological functions, including stimulation and maintenance of cellular immune responses. Structurally these proteins are short-chain 4-helical cytokines.


:

Pssm-ID: 308146  Cd Length: 129  Bit Score: 138.81  E-value: 2.67e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26787986    10 SCFSAGLPKTEAN---WVNVISDLKKIEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESG--DASIHDTV 84
Cdd:pfam02372   5 GCISAGLPKTEAYgasWSDVIKDLEIIENLINSIHIDATLYTESDTHPECKVTALQCFLLELRVILHESIedNEEIKEEV 84

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 26787986    85 ENLIILANNSLSS--NGNVTESGCKECEELEEKNIKEFLQSFVHI 127
Cdd:pfam02372  85 ENLIINANSNLSSlqDLNPTESGCKECEELEEKNFPEFLQSFVHI 129
 
Name Accession Description Interval E-value
IL15 pfam02372
Interleukin 15; Interleukin-15 (IL-15) is a cytokine that possesses a variety of biological ...
 10-127 2.67e-43

Interleukin 15; Interleukin-15 (IL-15) is a cytokine that possesses a variety of biological functions, including stimulation and maintenance of cellular immune responses. Structurally these proteins are short-chain 4-helical cytokines.


Pssm-ID: 308146  Cd Length: 129  Bit Score: 138.81  E-value: 2.67e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26787986    10 SCFSAGLPKTEAN---WVNVISDLKKIEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESG--DASIHDTV 84
Cdd:pfam02372   5 GCISAGLPKTEAYgasWSDVIKDLEIIENLINSIHIDATLYTESDTHPECKVTALQCFLLELRVILHESIedNEEIKEEV 84

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 26787986    85 ENLIILANNSLSS--NGNVTESGCKECEELEEKNIKEFLQSFVHI 127
Cdd:pfam02372  85 ENLIINANSNLSSlqDLNPTESGCKECEELEEKNFPEFLQSFVHI 129
 
Name Accession Description Interval E-value
IL15 pfam02372
Interleukin 15; Interleukin-15 (IL-15) is a cytokine that possesses a variety of biological ...
 10-127 2.67e-43

Interleukin 15; Interleukin-15 (IL-15) is a cytokine that possesses a variety of biological functions, including stimulation and maintenance of cellular immune responses. Structurally these proteins are short-chain 4-helical cytokines.


Pssm-ID: 308146  Cd Length: 129  Bit Score: 138.81  E-value: 2.67e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26787986    10 SCFSAGLPKTEAN---WVNVISDLKKIEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESG--DASIHDTV 84
Cdd:pfam02372   5 GCISAGLPKTEAYgasWSDVIKDLEIIENLINSIHIDATLYTESDTHPECKVTALQCFLLELRVILHESIedNEEIKEEV 84

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 26787986    85 ENLIILANNSLSS--NGNVTESGCKECEELEEKNIKEFLQSFVHI 127
Cdd:pfam02372  85 ENLIINANSNLSSlqDLNPTESGCKECEELEEKNFPEFLQSFVHI 129
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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