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Conserved domains on  [gi|24639563|ref|NP_726886|]
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Hsc/Hsp70-interacting protein related, isoform B [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
139-269 1.40e-14

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 72.26  E-value: 1.40e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 139 QQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRARRLLGDFELAAHDLR 218
Cdd:COG4785  86 LGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLE 165

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 24639563 219 QACKLD-FDEETDEWL----KEVTPNAKKIEQHRLKQERRQAERKIKERQRDQRRA 269
Cdd:COG4785 166 KALELDpNDPERALWLylaeRKLDPEKALALLLEDWATAYLLQGDTEEARELFKLA 221
Hip_N cd14438
N-terminal dimerization domain of the Hsp70-interacting protein (Hip) and similar proteins; ...
 10-47 2.43e-11

N-terminal dimerization domain of the Hsp70-interacting protein (Hip) and similar proteins; The Hsc70/Hsp70-interacting protein (Hip, also p48 or suppressor of tumorigenicity ST13) functions as a regulator of the cyclic action of Hsp70. Hip forms homodimers, and this model characterizes the N-terminal dimerization domain, which may not be directly involved in its regulatory function. A central domain of Hip that contains TPR repeats binds the ATPase domain of Hsp70 and slows the release of ADP.


:

Pssm-ID: 271228  Cd Length: 41  Bit Score: 57.94  E-value: 2.43e-11
                        10        20        30
                ....*....|....*....|....*....|....*...
gi 24639563  10 LKKLKYFIDFALENPTFLNMPQLQFVKDFVEKFGGTVP 47
Cdd:cd14438   4 LKELKAFVELCKQNPSILHTPELSFFKEYLESLGAKIP 41
STI1 smart00727
Heat shock chaperonin-binding motif;
299-336 3.34e-05

Heat shock chaperonin-binding motif;


:

Pssm-ID: 128966  Cd Length: 41  Bit Score: 40.71  E-value: 3.34e-05
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 24639563    299 DILGAMSDPEVSAAIQDILSNPGNITKYA-SNPKIYNLI 336
Cdd:smart00727   3 EMALRLQNPQVQSLLQDMQQNPDMLAQMLqENPQLLQLI 41
 
Name Accession Description Interval E-value
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
139-269 1.40e-14

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 72.26  E-value: 1.40e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 139 QQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRARRLLGDFELAAHDLR 218
Cdd:COG4785  86 LGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLE 165

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 24639563 219 QACKLD-FDEETDEWL----KEVTPNAKKIEQHRLKQERRQAERKIKERQRDQRRA 269
Cdd:COG4785 166 KALELDpNDPERALWLylaeRKLDPEKALALLLEDWATAYLLQGDTEEARELFKLA 221
Hip_N cd14438
N-terminal dimerization domain of the Hsp70-interacting protein (Hip) and similar proteins; ...
 10-47 2.43e-11

N-terminal dimerization domain of the Hsp70-interacting protein (Hip) and similar proteins; The Hsc70/Hsp70-interacting protein (Hip, also p48 or suppressor of tumorigenicity ST13) functions as a regulator of the cyclic action of Hsp70. Hip forms homodimers, and this model characterizes the N-terminal dimerization domain, which may not be directly involved in its regulatory function. A central domain of Hip that contains TPR repeats binds the ATPase domain of Hsp70 and slows the release of ADP.


Pssm-ID: 271228  Cd Length: 41  Bit Score: 57.94  E-value: 2.43e-11
                        10        20        30
                ....*....|....*....|....*....|....*...
gi 24639563  10 LKKLKYFIDFALENPTFLNMPQLQFVKDFVEKFGGTVP 47
Cdd:cd14438   4 LKELKAFVELCKQNPSILHTPELSFFKEYLESLGAKIP 41
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 126-235 6.91e-11

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 62.88  E-value: 6.91e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563  126 ASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRARR 205
Cdd:PLN03088   2 AKDLEDKAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACM 81

                         90       100       110
                 ....*....|....*....|....*....|.
gi 24639563  206 LLGDFELAAHDLRQACKLDFDE-ETDEWLKE 235
Cdd:PLN03088  82 KLEEYQTAKAALEKGASLAPGDsRFTKLIKE 112
HipN pfam18253
Hsp70-interacting protein N N-terminal domain; This is the N-terminal domain, known as HipN, ...
 9-47 9.88e-11

Hsp70-interacting protein N N-terminal domain; This is the N-terminal domain, known as HipN, found in Hsp70-interacting protein (Hip) present in Rattus norvegicus. Hip cooperates with the chaperone Hsp70 in protein folding and prevention of aggregation and may delay substrate release by slowing ADP dissociation from Hsp70. HipN is responsible for N-terminal homo-dimerization which is necessary so that the Hip dimer can interact with Hsp70 molecules.


Pssm-ID: 408069  Cd Length: 42  Bit Score: 56.13  E-value: 9.88e-11
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 24639563     9 DLKKLKYFIDFALENPTFLNMPQLQFVKDFVEKFGGTVP 47
Cdd:pfam18253   4 HLSLLKQFVDLCKANPSILHLPELAFFKEFLESLGATVP 42
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 78-266 5.58e-09

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 57.69  E-value: 5.58e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563    78 EDSEDEKSLSDPESDVELDMEGVIE-ADSDPAQPMGNYSKKATEEEVEQASELRAQAASAYGQQKFDEAIALYTKAIELS 156
Cdd:TIGR00990  78 KQAEKETEGKTEEKKSTAPKNAPVEpADELPEIDESSVANLSEEERKKYAAKLKEKGNKAYRNKDFNKAIKLYSKAIECK 157

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563   157 PgNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRARRLLGDFELAAHDLRQACKLD-FDEEtdewlke 235
Cdd:TIGR00990 158 P-DPVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLGKYADALLDLTASCIIDgFRNE------- 229

                         170       180       190
                  ....*....|....*....|....*....|.
gi 24639563   236 vtpnakKIEQHRLKQERRQAERKIKERQRDQ 266
Cdd:TIGR00990 230 ------QSAQAVERLLKKFAESKAKEILETK 254
TPR_11 pfam13414
TPR repeat;
137-173 9.79e-06

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 42.07  E-value: 9.79e-06
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 24639563   137 YGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKL 173
Cdd:pfam13414   5 YEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
STI1 smart00727
Heat shock chaperonin-binding motif;
299-336 3.34e-05

Heat shock chaperonin-binding motif;


Pssm-ID: 128966  Cd Length: 41  Bit Score: 40.71  E-value: 3.34e-05
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 24639563    299 DILGAMSDPEVSAAIQDILSNPGNITKYA-SNPKIYNLI 336
Cdd:smart00727   3 EMALRLQNPQVQSLLQDMQQNPDMLAQMLqENPQLLQLI 41
STI1 pfam17830
STI1 domain; This entry corresponds to the STI1 domain that is found in two copies in the Sti1 ...
 304-332 3.81e-03

STI1 domain; This entry corresponds to the STI1 domain that is found in two copies in the Sti1 protein.


Pssm-ID: 436075  Cd Length: 55  Bit Score: 35.23  E-value: 3.81e-03
                          10        20
                  ....*....|....*....|....*....
gi 24639563   304 MSDPEVSAAIQDILSNPGNITKYASNPKI 332
Cdd:pfam17830  18 LSDPEFVAKLQQIQKNPSSLQQYMQDPRV 46
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 127-233 6.36e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 37.99  E-value: 6.36e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 127 SELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLklkkpnacirdcdvalelnsdlaagykfrgrarrL 206
Cdd:cd24142   1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILL----------------------------------E 46

                        90       100
                ....*....|....*....|....*..
gi 24639563 207 LGDFELAAHDLRQACKLDFDEETDEWL 233
Cdd:cd24142  47 LGDVEEAREVLLRAIELDPDGGYEKYL 73
 
Name Accession Description Interval E-value
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
139-269 1.40e-14

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 72.26  E-value: 1.40e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 139 QQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRARRLLGDFELAAHDLR 218
Cdd:COG4785  86 LGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLE 165

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 24639563 219 QACKLD-FDEETDEWL----KEVTPNAKKIEQHRLKQERRQAERKIKERQRDQRRA 269
Cdd:COG4785 166 KALELDpNDPERALWLylaeRKLDPEKALALLLEDWATAYLLQGDTEEARELFKLA 221
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
116-224 2.96e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 71.58  E-value: 2.96e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 116 KKATEEEVEQASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAA 195
Cdd:COG0457  32 EKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAE 111

                        90       100
                ....*....|....*....|....*....
gi 24639563 196 GYKFRGRARRLLGDFELAAHDLRQACKLD 224
Cdd:COG0457 112 ALYNLGLALLELGRYDEAIEAYERALELD 140
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
116-278 3.02e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 71.58  E-value: 3.02e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 116 KKATEEEVEQASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAA 195
Cdd:COG0457  66 EQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDAD 145

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 196 GYKFRGRARRLLGDFELAAHDLRQACKLDFDEETDEWLKEVTPNAKKIEQHRLKQERRQAERKIKERQRDQRRARKEQEK 275
Cdd:COG0457 146 ALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLL 225


                ...
gi 24639563 276 HNA 278
Cdd:COG0457 226 ALA 228
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
120-226 5.89e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 70.81  E-value: 5.89e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 120 EEEVEQASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKF 199
Cdd:COG0457   2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNN 81

                        90       100
                ....*....|....*....|....*..
gi 24639563 200 RGRARRLLGDFELAAHDLRQACKLDFD 226
Cdd:COG0457  82 LGLALQALGRYEEALEDYDKALELDPD 108
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 124-224 2.24e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 71.56  E-value: 2.24e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 124 EQASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRA 203
Cdd:COG3914  76 LLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEA 155

                        90       100
                ....*....|....*....|.
gi 24639563 204 RRLLGDFELAAHDLRQACKLD 224
Cdd:COG3914 156 LRRLGRLEEAIAALRRALELD 176
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 124-224 5.25e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 67.33  E-value: 5.25e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 124 EQASELRAQAASAY--------GQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAA 195
Cdd:COG3914 102 RRALALNPDNAEALfnlgnlllALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAE 181

                        90       100
                ....*....|....*....|....*....
gi 24639563 196 GYKFRGRARRLLGDFELAAHDLRQACKLD 224
Cdd:COG3914 182 ALNNLGNALQDLGRLEEAIAAYRRALELD 210
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 124-224 7.53e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 62.52  E-value: 7.53e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 124 EQASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRA 203
Cdd:COG4783   2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                        90       100
                ....*....|....*....|.
gi 24639563 204 RRLLGDFELAAHDLRQACKLD 224
Cdd:COG4783  82 LLKAGDYDEALALLEKALKLD 102
Hip_N cd14438
N-terminal dimerization domain of the Hsp70-interacting protein (Hip) and similar proteins; ...
 10-47 2.43e-11

N-terminal dimerization domain of the Hsp70-interacting protein (Hip) and similar proteins; The Hsc70/Hsp70-interacting protein (Hip, also p48 or suppressor of tumorigenicity ST13) functions as a regulator of the cyclic action of Hsp70. Hip forms homodimers, and this model characterizes the N-terminal dimerization domain, which may not be directly involved in its regulatory function. A central domain of Hip that contains TPR repeats binds the ATPase domain of Hsp70 and slows the release of ADP.


Pssm-ID: 271228  Cd Length: 41  Bit Score: 57.94  E-value: 2.43e-11
                        10        20        30
                ....*....|....*....|....*....|....*...
gi 24639563  10 LKKLKYFIDFALENPTFLNMPQLQFVKDFVEKFGGTVP 47
Cdd:cd14438   4 LKELKAFVELCKQNPSILHTPELSFFKEYLESLGAKIP 41
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 126-235 6.91e-11

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 62.88  E-value: 6.91e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563  126 ASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRARR 205
Cdd:PLN03088   2 AKDLEDKAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACM 81

                         90       100       110
                 ....*....|....*....|....*....|.
gi 24639563  206 LLGDFELAAHDLRQACKLDFDE-ETDEWLKE 235
Cdd:PLN03088  82 KLEEYQTAKAALEKGASLAPGDsRFTKLIKE 112
HipN pfam18253
Hsp70-interacting protein N N-terminal domain; This is the N-terminal domain, known as HipN, ...
 9-47 9.88e-11

Hsp70-interacting protein N N-terminal domain; This is the N-terminal domain, known as HipN, found in Hsp70-interacting protein (Hip) present in Rattus norvegicus. Hip cooperates with the chaperone Hsp70 in protein folding and prevention of aggregation and may delay substrate release by slowing ADP dissociation from Hsp70. HipN is responsible for N-terminal homo-dimerization which is necessary so that the Hip dimer can interact with Hsp70 molecules.


Pssm-ID: 408069  Cd Length: 42  Bit Score: 56.13  E-value: 9.88e-11
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 24639563     9 DLKKLKYFIDFALENPTFLNMPQLQFVKDFVEKFGGTVP 47
Cdd:pfam18253   4 HLSLLKQFVDLCKANPSILHLPELAFFKEFLESLGATVP 42
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 121-224 1.30e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 59.20  E-value: 1.30e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 121 EEVEQASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFR 200
Cdd:COG5010  49 KLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNL 128

                        90       100
                ....*....|....*....|....
gi 24639563 201 GRARRLLGDFELAAHDLRQACKLD 224
Cdd:COG5010 129 AALLLSLGQDDEAKAALQRALGTS 152
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 116-232 1.66e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 58.48  E-value: 1.66e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 116 KKATEEEVEQASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAA 195
Cdd:COG4235   7 RQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPE 86

                        90       100       110
                ....*....|....*....|....*....|....*..
gi 24639563 196 GYKFRGRARRLLGDFELAAHDLRQAckLDFDEETDEW 232
Cdd:COG4235  87 ALYLLGLAAFQQGDYAEAIAAWQKL--LALLPADAPA 121
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 116-224 6.67e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 56.74  E-value: 6.67e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 116 KKATEEEVEQASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAA 195
Cdd:COG4783  28 EKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPE 107

                        90       100
                ....*....|....*....|....*....
gi 24639563 196 GYKFRGRARRLLGDFELAAHDLRQACKLD 224
Cdd:COG4783 108 AYLRLARAYRALGRPDEAIAALEKALELD 136
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 116-224 2.09e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.82  E-value: 2.09e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 116 KKATEEEVEQASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAA 195
Cdd:COG2956 100 EKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCAR 179

                        90       100
                ....*....|....*....|....*....
gi 24639563 196 GYKFRGRARRLLGDFELAAHDLRQACKLD 224
Cdd:COG2956 180 ALLLLAELYLEQGDYEEAIAALERALEQD 208
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
139-224 4.39e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 53.25  E-value: 4.39e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 139 QQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRdCDVALELNSDLAAGYKFRGRARRLLGDFELAAHDLR 218
Cdd:COG3063   5 LGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLE 83


                ....*.
gi 24639563 219 QACKLD 224
Cdd:COG3063  84 RALELD 89
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 78-266 5.58e-09

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 57.69  E-value: 5.58e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563    78 EDSEDEKSLSDPESDVELDMEGVIE-ADSDPAQPMGNYSKKATEEEVEQASELRAQAASAYGQQKFDEAIALYTKAIELS 156
Cdd:TIGR00990  78 KQAEKETEGKTEEKKSTAPKNAPVEpADELPEIDESSVANLSEEERKKYAAKLKEKGNKAYRNKDFNKAIKLYSKAIECK 157

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563   157 PgNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRARRLLGDFELAAHDLRQACKLD-FDEEtdewlke 235
Cdd:TIGR00990 158 P-DPVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLGKYADALLDLTASCIIDgFRNE------- 229

                         170       180       190
                  ....*....|....*....|....*....|.
gi 24639563   236 vtpnakKIEQHRLKQERRQAERKIKERQRDQ 266
Cdd:TIGR00990 230 ------QSAQAVERLLKKFAESKAKEILETK 254
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 113-262 1.17e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.51  E-value: 1.17e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 113 NYSKKATEEEVEQASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSD 192
Cdd:COG2956 131 EVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPD 210

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 193 LAAGYKFRGRARRLLGDFELAAHDLRQACKLDFDEETDEWLKEVTpnakkIEQHRLKQERRQAERKIKER 262
Cdd:COG2956 211 YLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLL-----ERKEGLEAALALLERQLRRH 275
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 116-268 1.32e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 53.46  E-value: 1.32e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 116 KKATEEEVEQASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAA 195
Cdd:COG3914 136 RRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNAD 215

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 196 GYKFRGRARRLLGDFELAAHDLRQACKLDFDEETDEW-----LKEVTPNAKKIEQHR---LKQERRQAERKIKERQRDQR 267
Cdd:COG3914 216 AHSNLLFALRQACDWEVYDRFEELLAALARGPSELSPfallyLPDDDPAELLALARAwaqLVAAAAAPELPPPPNPRDPD 295


                .
gi 24639563 268 R 268
Cdd:COG3914 296 R 296
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
153-226 3.15e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 51.16  E-value: 3.15e-07
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24639563 153 IELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRARRLLGDFELAAHDLRQACKLDFD 226
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPD 74
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 124-224 8.25e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.11  E-value: 8.25e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 124 EQASELRAQAASAYGQQK-FDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGR 202
Cdd:COG2956  73 PDRAEALLELAQDYLKAGlLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAE 152

                        90       100
                ....*....|....*....|..
gi 24639563 203 ARRLLGDFELAAHDLRQACKLD 224
Cdd:COG2956 153 LYLEQGDYDEAIEALEKALKLD 174
TPR_11 pfam13414
TPR repeat;
137-173 9.79e-06

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 42.07  E-value: 9.79e-06
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 24639563   137 YGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKL 173
Cdd:pfam13414   5 YEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
STI1 smart00727
Heat shock chaperonin-binding motif;
299-336 3.34e-05

Heat shock chaperonin-binding motif;


Pssm-ID: 128966  Cd Length: 41  Bit Score: 40.71  E-value: 3.34e-05
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 24639563    299 DILGAMSDPEVSAAIQDILSNPGNITKYA-SNPKIYNLI 336
Cdd:smart00727   3 EMALRLQNPQVQSLLQDMQQNPDMLAQMLqENPQLLQLI 41
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 141-226 5.94e-05

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 44.97  E-value: 5.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563   141 KFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRARRLLGDFELAAHDLRQA 220
Cdd:TIGR00990 346 KHLEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKS 425


                  ....*.
gi 24639563   221 CKLDFD 226
Cdd:TIGR00990 426 IDLDPD 431
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 144-224 6.46e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 42.30  E-value: 6.46e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 144 EAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRARRLLGDFELAAHDLRQACKL 223
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80


                .
gi 24639563 224 D 224
Cdd:COG4235  81 D 81
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 128-224 6.98e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 43.95  E-value: 6.98e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 128 ELRAQAASAYGQQK-FDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRARRL 206
Cdd:COG2956  43 EAHLALGNLYRRRGeYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQ 122

                        90
                ....*....|....*...
gi 24639563 207 LGDFELAAHDLRQACKLD 224
Cdd:COG2956 123 EGDWEKAIEVLERLLKLG 140
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 131-228 1.14e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 43.56  E-value: 1.14e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 131 AQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRARRLLGDF 210
Cdd:COG2956  13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLL 92

                        90
                ....*....|....*...
gi 24639563 211 ELAAHDLRQACKLDFDEE 228
Cdd:COG2956  93 DRAEELLEKLLELDPDDA 110
COG3899 COG3899
Predicted ATPase [General function prediction only];
121-223 1.24e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 44.08  E-value: 1.24e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563  121 EEVEQASEL------RAQAASAYgqqkfDEAIALYTKAIELSPGN------ALFHAKRGQAFLKLKKPNACIRDCDVALE 188
Cdd:COG3899  699 GERDRAARLllraarRALARGAY-----AEALRYLERALELLPPDpeeeyrLALLLELAEALYLAGRFEEAEALLERALA 773

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 24639563  189 LNSDLAAGYKFRGRARR-----------LLGDFELAAHDLRQACKL 223
Cdd:COG3899  774 ARALAALAALRHGNPPAsarayanlgllLLGDYEEAYEFGELALAL 819
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 127-192 2.00e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.95  E-value: 2.00e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24639563 127 SELRAQAASAYGQQ-KFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSD 192
Cdd:COG4783  72 PEARLNLGLALLKAgDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPD 138
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
111-193 2.21e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.77  E-value: 2.21e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 111 MGNYskKATEEEVEQASELRAQAASAY--------GQQKFDEAIAlYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRD 182
Cdd:COG3063   5 LGDL--EEAEEYYEKALELDPDNADALnnlgllllEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAY 81

                        90
                ....*....|.
gi 24639563 183 CDVALELNSDL 193
Cdd:COG3063  82 LERALELDPSA 92
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 120-207 2.48e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.15  E-value: 2.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563   120 EEEVEQASELRAQAASAY-GQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLaagyk 198
Cdd:TIGR02917 356 LGLDPDDPAALSLLGEAYlALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPEL----- 430


                  ....*....
gi 24639563   199 frGRARRLL 207
Cdd:TIGR02917 431 --GRADLLL 437
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 124-224 3.29e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 42.67  E-value: 3.29e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 124 EQASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRA 203
Cdd:COG3914  42 GLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNL 121

                        90       100
                ....*....|....*....|.
gi 24639563 204 RRLLGDFELAAHDLRQACKLD 224
Cdd:COG3914 122 LLALGRLEEALAALRRALALN 142
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 69-217 3.61e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.76  E-value: 3.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563    69 KANEPANAPEDSEDEKSLSDPESDVELDMEGVIEAdsdpaqpmGNYSKKATEEEVEQASE-----LRAQAASAY---GQQ 140
Cdd:TIGR02917 102 LQGKFQQVLDELPGKTLLDDEGAAELLALRGLAYL--------GLGQLELAQKSYEQALAidprsLYAKLGLAQlalAEN 173

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24639563   141 KFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRARRLLGDFELAAHDL 217
Cdd:TIGR02917 174 RFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHA 250
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 114-260 4.33e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.38  E-value: 4.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563   114 YSKKATEEEVEQASELRAQAASAY-GQQKFDEAIALYTKAIELSPGNAlfHAKRGQAFLKL--KKPNACIRDCDVALELN 190
Cdd:TIGR02917 112 ELPGKTLLDDEGAAELLALRGLAYlGLGQLELAQKSYEQALAIDPRSL--YAKLGLAQLALaeNRFDEARALIDEVLTAD 189

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563   191 SDLAAGYKFRGRARRLLGDFELAAHDLRQACKLDFDEETDEwLKEVTPNakkIEQHRLKQERRQAERKIK 260
Cdd:TIGR02917 190 PGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVL-LALATIL---IEAGEFEEAEKHADALLK 255
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 129-226 9.80e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.22  E-value: 9.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563   129 LRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRARRLLG 208
Cdd:TIGR02917 332 RRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQG 411

                          90
                  ....*....|....*...
gi 24639563   209 DFELAAHDLRQACKLDFD 226
Cdd:TIGR02917 412 DPSEAIADLETAAQLDPE 429
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 116-190 1.46e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.79  E-value: 1.46e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24639563 116 KKATEEEVEQASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELN 190
Cdd:COG5010  78 EQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
130-275 1.48e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 39.87  E-value: 1.48e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 130 RAQAASAY-GQQKFDEAIALYTKAIE-LSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDlaagYKF------RG 201
Cdd:COG4700  92 RVRLADALlELGRYDEAIELYEEALTgIFADDPHILLGLAQALFELGRYAEALETLEKLIAKNPD----FKSsdahllYA 167

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 202 RARRLLGDFELAAHDLRQACKLDFDEET----DEWLKEV--TPNAKKIEQhRLKQERRQAERKIKERQRDQ-RRARKEQE 274
Cdd:COG4700 168 RALEALGDLEAAEAELEALARRYSGPEAryryAKFLARQgrTAEAKELLE-EILDEAKHMPKHYRRLNREWiREAKKLLK 246


                .
gi 24639563 275 K 275
Cdd:COG4700 247 S 247
STI1 pfam17830
STI1 domain; This entry corresponds to the STI1 domain that is found in two copies in the Sti1 ...
 304-332 3.81e-03

STI1 domain; This entry corresponds to the STI1 domain that is found in two copies in the Sti1 protein.


Pssm-ID: 436075  Cd Length: 55  Bit Score: 35.23  E-value: 3.81e-03
                          10        20
                  ....*....|....*....|....*....
gi 24639563   304 MSDPEVSAAIQDILSNPGNITKYASNPKI 332
Cdd:pfam17830  18 LSDPEFVAKLQQIQKNPSSLQQYMQDPRV 46
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 124-224 3.87e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 37.63  E-value: 3.87e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 124 EQASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRA 203
Cdd:COG5010  18 TKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALL 97

                        90       100
                ....*....|....*....|.
gi 24639563 204 RRLLGDFELAAHDLRQACKLD 224
Cdd:COG5010  98 YSRSGDKDEAKEYYEKALALS 118
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 126-158 4.13e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 34.42  E-value: 4.13e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 24639563   126 ASELRAQAASAYGQQKFDEAIALYTKAIELSPG 158
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 127-233 6.36e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 37.99  E-value: 6.36e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639563 127 SELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLklkkpnacirdcdvalelnsdlaagykfrgrarrL 206
Cdd:cd24142   1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILL----------------------------------E 46

                        90       100
                ....*....|....*....|....*..
gi 24639563 207 LGDFELAAHDLRQACKLDFDEETDEWL 233
Cdd:cd24142  47 LGDVEEAREVLLRAIELDPDGGYEKYL 73
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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