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Conserved domains on  [gi|227496929|ref|NP_666062|]
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oxidative stress-induced growth inhibitor 2 isoform 1 [Mus musculus]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 1000380)

NAD(P)/FAD-dependent oxidoreductase catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant

CATH:  3.50.50.60
EC:  1.-.-.-
Gene Ontology:  GO:0016491
SCOP:  4000117

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CzcO super family cl34398
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
161-361 5.31e-07

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


The actual alignment was detected with superfamily member COG2072:

Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 52.17  E-value: 5.31e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227496929 161 IPHLVLGKGP-PGGAWHNM--EGSMLTISfgNWM-ELPGLQFkdWisskrrnlKGDRVMP--EEIARYYKHYVKVMGLQK 234
Cdd:COG2072   30 IDFVVLEKADdVGGTWRDNryPGLRLDTP--SHLySLPFFPN--W--------SDDPDFPtgDEILAYLEAYADKFGLRR 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227496929 235 NFRENTYITSVSrlyRDQGDNGsqdrdistkhlqnqkskfikrnWEIrgyqRIAGGSHvpfcLFAENVALATGTLDSPAH 314
Cdd:COG2072   98 PIRFGTEVTSAR---WDEADGR----------------------WTV----TTDDGET----LTARFVVVATGPLSRPKI 144
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 227496929 315 LEVEGEEfPF---VFHSmpefgAAIN-----KGKlcgrvdPVLIVGSGLTAADAV 361
Cdd:COG2072  145 PDIPGLE-DFageQLHS-----ADWRnpvdlAGK------RVLVVGTGASAVQIA 187
 
Name Accession Description Interval E-value
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
161-361 5.31e-07

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 52.17  E-value: 5.31e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227496929 161 IPHLVLGKGP-PGGAWHNM--EGSMLTISfgNWM-ELPGLQFkdWisskrrnlKGDRVMP--EEIARYYKHYVKVMGLQK 234
Cdd:COG2072   30 IDFVVLEKADdVGGTWRDNryPGLRLDTP--SHLySLPFFPN--W--------SDDPDFPtgDEILAYLEAYADKFGLRR 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227496929 235 NFRENTYITSVSrlyRDQGDNGsqdrdistkhlqnqkskfikrnWEIrgyqRIAGGSHvpfcLFAENVALATGTLDSPAH 314
Cdd:COG2072   98 PIRFGTEVTSAR---WDEADGR----------------------WTV----TTDDGET----LTARFVVVATGPLSRPKI 144
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 227496929 315 LEVEGEEfPF---VFHSmpefgAAIN-----KGKlcgrvdPVLIVGSGLTAADAV 361
Cdd:COG2072  145 PDIPGLE-DFageQLHS-----ADWRnpvdlAGK------RVLVVGTGASAVQIA 187
 
Name Accession Description Interval E-value
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
161-361 5.31e-07

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 52.17  E-value: 5.31e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227496929 161 IPHLVLGKGP-PGGAWHNM--EGSMLTISfgNWM-ELPGLQFkdWisskrrnlKGDRVMP--EEIARYYKHYVKVMGLQK 234
Cdd:COG2072   30 IDFVVLEKADdVGGTWRDNryPGLRLDTP--SHLySLPFFPN--W--------SDDPDFPtgDEILAYLEAYADKFGLRR 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227496929 235 NFRENTYITSVSrlyRDQGDNGsqdrdistkhlqnqkskfikrnWEIrgyqRIAGGSHvpfcLFAENVALATGTLDSPAH 314
Cdd:COG2072   98 PIRFGTEVTSAR---WDEADGR----------------------WTV----TTDDGET----LTARFVVVATGPLSRPKI 144
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 227496929 315 LEVEGEEfPF---VFHSmpefgAAIN-----KGKlcgrvdPVLIVGSGLTAADAV 361
Cdd:COG2072  145 PDIPGLE-DFageQLHS-----ADWRnpvdlAGK------RVLVVGTGASAVQIA 187
YdhS COG4529
Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];
286-362 9.31e-05

Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];


Pssm-ID: 443597 [Multi-domain]  Cd Length: 466  Bit Score: 44.95  E-value: 9.31e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 227496929 286 RIAGGSHVPfclfAENVALATGTLdSPAHLEVEGEEFPFVFHSM--PEFGAAINKGklcgrvDPVLIVGSGLTAADAVL 362
Cdd:COG4529  142 TLADGETLR----ADAVVLATGHP-PPAPPPGLAAGSPRYIADPwpPGALARIPPD------ARVLIIGTGLTAIDVVL 209
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
302-364 4.48e-04

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 42.81  E-value: 4.48e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 227496929 302 VALATGTLDsPAHLEVEGEEFPFVFHSMpEFGAAINKGKLCGRVDP----VLIVGSGLTAADAVLCA 364
Cdd:COG0493  210 VFLATGAGK-PRDLGIPGEDLKGVHSAM-DFLTAVNLGEAPDTILAvgkrVVVIGGGNTAMDCARTA 274
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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