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Conserved domains on  [gi|22122355|ref|NP_666045|]
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beta-galactoside alpha-2,6-sialyltransferase 1 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GT29_ST6GAL1 cd23985
beta-galactoside alpha-2,6-sialyltransferase 1; ST6Gal family members are beta-galactoside ...
 134-398 0e+00

beta-galactoside alpha-2,6-sialyltransferase 1; ST6Gal family members are beta-galactoside alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the terminal galactose residue of a glycochain, by transfering sialic acid from CMP-Sia. ST6Gal1 play important roles in the immune system. The ST6Gal family belongs to the glycosyltransferase family 29 (GT29).


:

Pssm-ID: 467713  Cd Length: 266  Bit Score: 563.18  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 134 VEALRCHLRDHVNVSMIEATDFPFNTTEWEGYLPKENFRTKAGPWHKCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPT 213
Cdd:cd23985   1 AEELLCELKDKVNVSMLEGTDFPFNTSEWEGYLPKKSLREEVGPLGRCAVVSSAGSLKSSGLGREIDSHDAVLRFNGAPT 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 214 DNFQQDVGTKTTIRLVNSQLVTTEKR-FLKDSLYTEGILILWDPSVYHADIPQWYQKPDYNFFETYKSYRRLHPSQPFYI 292
Cdd:cd23985  81 AGFQQDVGTKTTIRLINSQLVTTEKHkFLKDSLYNEGILIVWDPAPYHSDIPEWYKNPDYNFFENYKTYRRLNPNQPFYI 160

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 293 LKPQMPWELWDIIQEISPDLIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYHQKFFDSACTMGAYHPLLFE 372
Cdd:cd23985 161 LHPQMQWELWDIIQENSPEEIQPNPPSSGMLGIILMMTLCDQVDVYEFLPSKRKTDVCHYYQKFFDRACTMGAYHPLLYE 240

                       250       260
                ....*....|....*....|....*.
gi 22122355 373 KNMVKHLNEGTDEDIYLFGKATLSGF 398
Cdd:cd23985 241 KNLVKHLNQGTDEDIYLLGKVTLPGF 266
 
Name Accession Description Interval E-value
GT29_ST6GAL1 cd23985
beta-galactoside alpha-2,6-sialyltransferase 1; ST6Gal family members are beta-galactoside ...
 134-398 0e+00

beta-galactoside alpha-2,6-sialyltransferase 1; ST6Gal family members are beta-galactoside alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the terminal galactose residue of a glycochain, by transfering sialic acid from CMP-Sia. ST6Gal1 play important roles in the immune system. The ST6Gal family belongs to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467713  Cd Length: 266  Bit Score: 563.18  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 134 VEALRCHLRDHVNVSMIEATDFPFNTTEWEGYLPKENFRTKAGPWHKCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPT 213
Cdd:cd23985   1 AEELLCELKDKVNVSMLEGTDFPFNTSEWEGYLPKKSLREEVGPLGRCAVVSSAGSLKSSGLGREIDSHDAVLRFNGAPT 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 214 DNFQQDVGTKTTIRLVNSQLVTTEKR-FLKDSLYTEGILILWDPSVYHADIPQWYQKPDYNFFETYKSYRRLHPSQPFYI 292
Cdd:cd23985  81 AGFQQDVGTKTTIRLINSQLVTTEKHkFLKDSLYNEGILIVWDPAPYHSDIPEWYKNPDYNFFENYKTYRRLNPNQPFYI 160

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 293 LKPQMPWELWDIIQEISPDLIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYHQKFFDSACTMGAYHPLLFE 372
Cdd:cd23985 161 LHPQMQWELWDIIQENSPEEIQPNPPSSGMLGIILMMTLCDQVDVYEFLPSKRKTDVCHYYQKFFDRACTMGAYHPLLYE 240

                       250       260
                ....*....|....*....|....*.
gi 22122355 373 KNMVKHLNEGTDEDIYLFGKATLSGF 398
Cdd:cd23985 241 KNLVKHLNQGTDEDIYLLGKVTLPGF 266
Glyco_transf_29 pfam00777
Glycosyltransferase family 29 (sialyltransferase); Members of this family belong to ...
 166-379 1.93e-28

Glycosyltransferase family 29 (sialyltransferase); Members of this family belong to glycosyltransferase family 29.


Pssm-ID: 459935  Cd Length: 256  Bit Score: 111.93  E-value: 1.93e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355   166 LPKENfRTKAGPWHKCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTTIRLVN--SQLVTTEKRFLKD 243
Cdd:pfam00777  32 LPKVS-PFDNKRCRRCAVVGNGGILRGSGCGKEIDSHDFVIRCNLAPTKGYEKDVGSKTTLRTMNpeSAIDSKYGNLGFS 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355   244 SLYTEGIL----------ILWDPS-VYHADIPqwyqkPDYNFFETYKSYR-RLHPSQpFYILKPqmpwelwDIIQEISPD 311
Cdd:pfam00777 111 HPRDPFVEfvlvpfkgrdLLWLPAfLTKGNVS-----RSLRVLYTLKEVKiPVDPDK-VLFLHP-------DFLRYVANF 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355   312 L-----IQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSkrktdvcYYHQKF----FDSAC--TMGAY--HPLLFEKNMVKH 378
Cdd:pfam00777 178 WlrshgLKGRRPSTGLLMLSLALHLCDEVSLYGFGPF-------LDSRGNshhyYDNVLmkKGGFYgvHDMPFEFKLLQK 250


                  .
gi 22122355   379 L 379
Cdd:pfam00777 251 L 251
 
Name Accession Description Interval E-value
GT29_ST6GAL1 cd23985
beta-galactoside alpha-2,6-sialyltransferase 1; ST6Gal family members are beta-galactoside ...
 134-398 0e+00

beta-galactoside alpha-2,6-sialyltransferase 1; ST6Gal family members are beta-galactoside alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the terminal galactose residue of a glycochain, by transfering sialic acid from CMP-Sia. ST6Gal1 play important roles in the immune system. The ST6Gal family belongs to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467713  Cd Length: 266  Bit Score: 563.18  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 134 VEALRCHLRDHVNVSMIEATDFPFNTTEWEGYLPKENFRTKAGPWHKCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPT 213
Cdd:cd23985   1 AEELLCELKDKVNVSMLEGTDFPFNTSEWEGYLPKKSLREEVGPLGRCAVVSSAGSLKSSGLGREIDSHDAVLRFNGAPT 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 214 DNFQQDVGTKTTIRLVNSQLVTTEKR-FLKDSLYTEGILILWDPSVYHADIPQWYQKPDYNFFETYKSYRRLHPSQPFYI 292
Cdd:cd23985  81 AGFQQDVGTKTTIRLINSQLVTTEKHkFLKDSLYNEGILIVWDPAPYHSDIPEWYKNPDYNFFENYKTYRRLNPNQPFYI 160

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 293 LKPQMPWELWDIIQEISPDLIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYHQKFFDSACTMGAYHPLLFE 372
Cdd:cd23985 161 LHPQMQWELWDIIQENSPEEIQPNPPSSGMLGIILMMTLCDQVDVYEFLPSKRKTDVCHYYQKFFDRACTMGAYHPLLYE 240

                       250       260
                ....*....|....*....|....*.
gi 22122355 373 KNMVKHLNEGTDEDIYLFGKATLSGF 398
Cdd:cd23985 241 KNLVKHLNQGTDEDIYLLGKVTLPGF 266
GT29_ST6GAL1_2 cd23968
beta-galactoside alpha-2,6-sialyltransferase 1 and 2; ST6Gal family members are ...
 135-398 2.68e-142

beta-galactoside alpha-2,6-sialyltransferase 1 and 2; ST6Gal family members are beta-galactosidealpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acidand the terminal galactose residue of a glycochain, by transfering sialic acid fromCMP-Sia. The ST6Gal family belongs to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467696  Cd Length: 266  Bit Score: 405.50  E-value: 2.68e-142
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 135 EALRCHLRDHVNVSMIEATDFPFNTTEWEGYLPKENFRTKAGPWHKCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTD 214
Cdd:cd23968   2 EDLLCRLKKAAPFSTLRKTTSPFKDLLSLRYPFPESSLENTKRYNTCAVVSSSGALLGSKLGKEIDSHDAVLRFNDAPTK 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 215 NFQQDVGTKTTIRLVNSQLVT-TEKRFLKDSLYTEGILILWDPSVYHADIPQWYQKPDYNFFETYKSYRRLHPSQPFYIL 293
Cdd:cd23968  82 GFEKDVGSKTTLRLINSQILSkPEFNFLTDPLYRNVTLLVWDPSSYNVNLEKWYKKPDFDFFPNYIKYRRRHPEEPFYLI 161

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 294 KPQMPWELWDIIQEISPDLIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYHQKFFDSACTMGAYHPLLFEK 373
Cdd:cd23968 162 DPRFLWRLWDILQEYTPEKIKPNPPSSGFIGIVLMLHLCDWVDVYEYVPSVRQTDRCHYYDVEKDLACTLGAWHPLAAEK 241

                       250       260
                ....*....|....*....|....*
gi 22122355 374 NMVKHLNEGTDEDIYLFGKATLSGF 398
Cdd:cd23968 242 LLVRHLNVGSDDDIFRKGRATLPGF 266
GT29_ST6GAL2 cd23986
beta-galactoside alpha-2,6-sialyltransferase 2; ST6Gal family members are beta-galactoside ...
 131-398 8.21e-122

beta-galactoside alpha-2,6-sialyltransferase 2; ST6Gal family members are beta-galactoside alpha-2,3-sialyltransferases that catalyze an alpha2,6-linkage between sialic acid and the terminal galactose residue of a glycochain, by a transfering sialic acid from CMP-Sia. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467714  Cd Length: 270  Bit Score: 353.76  E-value: 8.21e-122
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 131 KFSVEALRCHLRDHVNVSMIEATDFPFNTTEWEGYLPKENF-RTKAGPWHKCAVVSSAGSLKNSQLGREIDNHDAVLRFN 209
Cdd:cd23986   1 KLSRQELLCELKKRVQVRTLDGKEAPFSALGWEKYVPKIPLsKLHLRGFRSCAVVTSAGAILNSSLGKEIDSHDAVLRFN 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 210 GAPTDNFQQDVGTKTTIRLVNSQLVTTEK-RFLKDSLYTEGILILWDPSVYHADIPQWYQKPDYNFFETYKSYRRLHPSQ 288
Cdd:cd23986  81 SAPTRGYEKDVGNKTTIRIINSQILTNPNhHFIDSSLYKDVILVAWDPAPYSANLHKWYKKPDYNLFTPYVQYRKRNPNQ 160

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 289 PFYILKPQMPWELWDIIQEISPDLIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYHQKFFDSACTMGAYHP 368
Cdd:cd23986 161 PFYILHPKFIWQLWDIIQENTQEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTDLCHYHERYYDAACTLGAYHP 240

                       250       260       270
                ....*....|....*....|....*....|
gi 22122355 369 LLFEKNMVKHLNEGTDEDIYLFGKATLSGF 398
Cdd:cd23986 241 LLYEKLLIQRMNKGTEDDLYRKGKVILPGF 270
GT29 cd19952
glycosyltransferase family 29; Glycosyltransferase family 29 members (also called ...
 181-379 1.02e-51

glycosyltransferase family 29; Glycosyltransferase family 29 members (also called sialyltransferases) are enzymes that transfer sialic acid to oligosaccharide, each having specificity for a certain sugar substrate.


Pssm-ID: 467690  Cd Length: 193  Bit Score: 171.78  E-value: 1.02e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 181 CAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTTIRLVNSQLV-----TTEKRFLKDSLYTEGILILWD 255
Cdd:cd19952   1 CAVVGNSGILLGSEYGKEIDSHDAVFRFNQAPTKGFEKDVGSKTTFRVLNSKWAgfylrGPRCGCHPLPLEEEVVLILSR 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 256 PSVYhadipqwyqkpdynFFETYKSYRRLHPSQPFYILK--PQMPWELWDIIQEISPDLIQ-PNPPSSGMLGIIIMMTLC 332
Cdd:cd19952  81 AAAA--------------DFKRLKRRKKRHDNAVLLLTDpaPDLLSYVRKRLEKLGLKSFFgGNAPSSGLLAVLLALQLC 146

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*....
gi 22122355 333 DQVDIYEF--LPSKRKTDVCYYHQKFFDSActMGAYHPLLFEKNMVKHL 379
Cdd:cd19952 147 DSVDLYGFgvDSGHAPKVPYHYYDLVEAEE--GTAVHSFDLEAELLRAL 193
Glyco_transf_29 pfam00777
Glycosyltransferase family 29 (sialyltransferase); Members of this family belong to ...
 166-379 1.93e-28

Glycosyltransferase family 29 (sialyltransferase); Members of this family belong to glycosyltransferase family 29.


Pssm-ID: 459935  Cd Length: 256  Bit Score: 111.93  E-value: 1.93e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355   166 LPKENfRTKAGPWHKCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTTIRLVN--SQLVTTEKRFLKD 243
Cdd:pfam00777  32 LPKVS-PFDNKRCRRCAVVGNGGILRGSGCGKEIDSHDFVIRCNLAPTKGYEKDVGSKTTLRTMNpeSAIDSKYGNLGFS 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355   244 SLYTEGIL----------ILWDPS-VYHADIPqwyqkPDYNFFETYKSYR-RLHPSQpFYILKPqmpwelwDIIQEISPD 311
Cdd:pfam00777 111 HPRDPFVEfvlvpfkgrdLLWLPAfLTKGNVS-----RSLRVLYTLKEVKiPVDPDK-VLFLHP-------DFLRYVANF 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355   312 L-----IQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSkrktdvcYYHQKF----FDSAC--TMGAY--HPLLFEKNMVKH 378
Cdd:pfam00777 178 WlrshgLKGRRPSTGLLMLSLALHLCDEVSLYGFGPF-------LDSRGNshhyYDNVLmkKGGFYgvHDMPFEFKLLQK 250


                  .
gi 22122355   379 L 379
Cdd:pfam00777 251 L 251
GT29_ST8SIA cd23963
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; ST8Sia family members are ...
 165-342 6.08e-25

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; ST8Sia family members are alpha-N-acetylneuraminidealpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia. The family is subdivided into 3 classes of enzymes, depending on their catalytic activiy, the mono-STs (ST8Sia1, ST8Sia5 and ST8Sia6), the oligo-ST(ST8Sia3), and the poly-STs (ST8Sia2 and ST8Sia4). The ST8Sia family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467691  Cd Length: 274  Bit Score: 102.72  E-value: 6.08e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 165 YLPKEN-FRTKagPWHKCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKT--------TIRLVNSQLVT 235
Cdd:cd23963  51 LLPKTSpFSHK--RYKTCAVVGNSGILLGSGCGKEIDSHDFVIRCNLPPIKGFEKDVGRKTnlttlnpsILKRRYNSLKK 128

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 236 TE--KRFLKD-SLYTEGILilwdpsVYHADIPQWYQKPdynFFETYKSYRRLHPSQPFYILKPQMP---WELWdiiqeis 309
Cdd:cd23963 129 NRdrDKFLNRlKEYNGSIL------WYPKFSFKSSTNL---LLKAARALKKNGLNLTVVYSNPEHFlavQKFW------- 192

                       170       180       190
                ....*....|....*....|....*....|...
gi 22122355 310 PDLIQPNPPSSGMLGIIIMMTLCDQVDIYEFLP 342
Cdd:cd23963 193 KRRGLEKRPSTGLYLVSLALTFCDEIHLYGFWP 225
GT29_ST6GALNAC3_4_5_6 cd23965
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3, 4, 5 and 6; ST6GalNAc family ...
 179-367 5.26e-24

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3, 4, 5 and 6; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acidand the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, bytransfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilizeSia2,3Galbeta1,3GalNAc as an acceptor with different individual substratespecificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467693  Cd Length: 225  Bit Score: 98.85  E-value: 5.26e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 179 HKCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTTIRLV---NSQLVTTEKRFLKDSLYTEGILILWD 255
Cdd:cd23965   2 DTCALVSSSGQLLGSGAGKEIDSADCVIRMNDAPTRGYEKDVGRRTTIRVVshsSLPRLLRNAILLLAGTRAPTVVVFWG 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 256 PSVYhadipqwYQKPDYNFFETYKSYRRLHPSQPFYILKPQMpwELW-DII--QEISPDLIQPNP-PSSGMLGIIIMMTL 331
Cdd:cd23965  82 PETK-------MNKDGAGKYNLLRSLSKKYPDVEFYSLTPEK--MDYaDELfeKETGKSRIKSGTwLSTGWFTMLLALDV 152

                       170       180       190       200
                ....*....|....*....|....*....|....*....|..
gi 22122355 332 CDQVDIYEFLPSK-----RKTDVCY-YHQKFFDSACTMGAYH 367
Cdd:cd23965 153 CDEIKVYGMVPENycrehPNSKVPYhYYEPGGLKECTYYNYH 194
GT29_ST3GAL3_4_5_6 cd23967
beta-galactoside alpha-2,3-sialyltransferase 3,4,5 and 6; ST3GAL family transfers sialic acid ...
 180-379 4.32e-23

beta-galactoside alpha-2,3-sialyltransferase 3,4,5 and 6; ST3GAL family transfers sialic acid from CMP-Sia to the terminalgalactose residues of glycochains through an 2,3-linkage. ST3GAL3 and 4 utilize bothGalbeta1,3GlcNAc and Galbeta1,4GlcNAc, mainly on glycoproteins and oligosaccharidesas acceptor substrates. ST3GAL5 is also known as GM3 ganglioside synthase. ST3GAL6 utilizes the Galbeta1,4GlcNAc on glycoproteins and glycolipids as an acceptor. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467695  Cd Length: 205  Bit Score: 95.82  E-value: 4.32e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 180 KCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTTIRlvnsqLVTTEKRFLKDSLYTEGILILWDPsvY 259
Cdd:cd23967   4 RCVVVGNGGVLKGKSLGSVIDKYDVVIRMNDAPVKGYEKDVGSKTTFR-----MFYPESAFRDPEEYDSDWLLVLVP--F 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 260 HADIPQWYQ------KPDYNFFETYKSYRRLH-PSQPFYILKPQMPWEL-WDIIQEISPDLIQPNPPSSGMLGIIIMMTL 331
Cdd:cd23967  77 KSMDLLWLQavikgkKPNGKGGFWKKIATSVPkPPKKIRILNPYILQEAaFDLIGLPMNGKQGKNVPTTGIIAIVMALHY 156

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....
gi 22122355 332 CDQVDI--YEFLPSKRKTDVCYYhqkffDSACT----MGAYHPLLFEKNMVKHL 379
Cdd:cd23967 157 CDEVDIagFGYDPSDPNAPLHYY-----DSLTMkaikRSWTHNVTKEKKYLKKL 205
GT29_ST6GALNAC6 cd23978
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; ST6GalNAc family members are ...
 179-373 1.45e-17

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilizeSia2,3Galbeta1,3GalNAc as an acceptor with different individual substrate specificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467706  Cd Length: 229  Bit Score: 81.05  E-value: 1.45e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 179 HKCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTTIRLVN----SQLVTTEKRFLkdSLYTEGILILW 254
Cdd:cd23978   2 HQCALITSSSHLLGTSLGPEIDQTECTIRMNDAPTTGYEKDVGNKTTLRVVAhssvYRVLRRPQEFL--NRTPETTLIFW 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 255 DPsvyhadiPQWYQKPDY-NFFETYKSYRRLHPSQPFYILKPQMPWELWDIIQ-EISPDLIQPNP-PSSGMLGIIIMMTL 331
Cdd:cd23978  80 GP-------PNKMQKDGKsNLFRIIQRASMTFPNMSAFVVSPRRMRQFDDLFRgETGRDRKKSHSwLSTGWFTMVIAVEL 152

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 22122355 332 CDQVDIYEFLP----SKR----KTDVCYYHQKFFDSACT--------MGAYHPLLFEK 373
Cdd:cd23978 153 CDNVHVYGMVPpnycSKRptpkKMPYHYYEPKGPDECVTyiqnehgrRGNHHRFITEK 210
GT29_ST3GAL4 cd23982
beta-galactoside alpha-2,3-sialyltransferase 4; ST3GAL family transfers sialic acid from ...
 180-379 2.18e-17

beta-galactoside alpha-2,3-sialyltransferase 4; ST3GAL family transfers sialic acid from CMP-Sia to the terminal galactose residues of glycochains through an 2,3-linkage. ST3GAL4 can utilize both Galbeta1,3GlcNAc and Galbeta1,4GlcNAc, mainly on glycoproteins and oligosaccharidesas acceptor substrates, but prefers the Galbeta1,4GlcNAc. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467710  Cd Length: 204  Bit Score: 80.09  E-value: 2.18e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 180 KCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTTIRLV--NSQLVTTEKRFLKDSLYtegILILWDPS 257
Cdd:cd23982   4 RCVVVGNGHNLKNSSLGDVIDSYDVVIRLNDAPVRGFEKDVGSKTTIRLFypESAQFDPGIENDPDTLL---VLVPFKPL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 258 vyhaDIpQW-------YQKPDYNFFETYKSYRRLHPSQpFYILKPQMPWELWDIIQEISPDLIQPNPPSSGMLGIIIMMT 330
Cdd:cd23982  81 ----DF-YWlyeilsnEKRVRKGFWKQPPRIWDANPKQ-IRILNPYYTYVAATKLLQVPGQRKKKQKPTTGLLAITLALH 154

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|..
gi 22122355 331 LCDQVDIYEF---LPSKRKTDVCYYHQKFFDSacTMGAYHPLLFEKNMVKHL 379
Cdd:cd23982 155 LCDEVHIAGFgypDNGNSNQPIHYYNQITLKS--MANSGHNLNAEAQAIQRL 204
GT29_ST6GALNAC1_2 cd23964
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 and 2; ST6GalNAc family members ...
 180-358 3.29e-17

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 and 2; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc1 and 2 utilize mainly GalNAc-,Galbeta1,3GalNAc-, and Sia2,3Galbeta1,3GalNAc on O-glycans of glycoproteins as acceptors. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467692  Cd Length: 292  Bit Score: 81.15  E-value: 3.29e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 180 KCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTT--IRLVNSQLVTTEKRFL--KDSLYtegILILWD 255
Cdd:cd23964  84 RCAVVGNGGILNGSGKGKEIDAHDYVFRVNHALTKGFEKDVGTKTSfyTFFPESLHNSLLKHVPqdKDTKY---LFIPFK 160

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 256 PSVYH--ADIPQWyqKPDYNFFETYKSYRRLHPSQP----FYILKPqmpwelwDIIQEI------SPDLiqpNPPSSGML 323
Cdd:cd23964 161 IRDYDylDAVLSG--KPVPDGCDKGKRPPPLFGPKLnatnVRLLHP-------DFIRYLfnrwlnSSTS---YRPTTGAL 228

                       170       180       190
                ....*....|....*....|....*....|....*
gi 22122355 324 GIIIMMTLCDQVDIYEFLPSKRKTDVcYYHQKFFD 358
Cdd:cd23964 229 MLLTALHTCDQVSVYGFGYDPRFSLH-YYDKTFVK 262
GT29_ST8SIA3_oligo cd23970
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 3; Alpha-N-acetylneuraminide alpha-2, ...
 180-379 4.57e-16

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 3; Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 3 synthesizes polysialic acid and has been shown to autopolysialylate. ST8Sia3 utilizes the Siaalpha2,3Galbeta1,4GlcNAc structure on N-glycans of glycoproteins and glycolipids as acceptor substrates. ST8Sia family members are alpha-N-acetylneuraminidealpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acidand the terminal sialic acid residues of glycochains, by transfering sialic acidfrom CMP-Sia and they belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467698  Cd Length: 284  Bit Score: 77.82  E-value: 4.57e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 180 KCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTTI----------RLVNSQLVTTEKRFLKDsLYTEG 249
Cdd:cd23970  70 TCAVVGNSGILTNSQCGNEIDKSDFVFRCNFAPTEGFEKDVGRKTNLttfnpsilekYYNNLLTIQDRNNFFLS-LKKLD 148

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 250 ILILWDPSV-YHADIPQWYQKPDynFFETYKSYRRLHPSQPFYIlkpqMPW--ELWDiIQEISPDLIqpnppSSGMLGII 326
Cdd:cd23970 149 GAILWIPAFfFHTSATVTRTLVD--FFVEHRGQLKVQLAWPGNI----MQHvnRYWK-TKHLSPKRL-----STGILMYT 216

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 22122355 327 IMMTLCDQVDIYEFLP---SKRKTDVCYYHQKFFDSACTMG--AYHPLLFEKNMVKHL 379
Cdd:cd23970 217 LASAICEEIHLYGFWPfgfDPTGTPLPYHYYDKKGTKFTTKwqESHQLPAEFVLLYKM 274
GT29_ST6GALNAC4 cd23977
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4; ST6GalNAc family members are ...
 180-367 1.05e-15

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilizeSia2,3Galbeta1,3GalNAc as an acceptor with different individual substrate specificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467705  Cd Length: 228  Bit Score: 75.67  E-value: 1.05e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 180 KCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTTIRLVNSQ----LVTTEKRFLKDSLYTegILILWD 255
Cdd:cd23977   3 RCAVVSSSGQMLGSGLGPEIDQQECVLRMNVAPTAGYEADVGNRSSLRVVSHTsvplLLRNQGYFFQQSRDT--KYVIWG 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 256 PSvyhADIPQWYQKPDYNFFETYKsyrRLHPSQPFYILKPQMPWELWDIIQ-EISPDLIQPNP-PSSGMLGIIIMMTLCD 333
Cdd:cd23977  81 PE---RNMDRDGGGKTYRALLTLA---KMYPHLQVYTLTEEKMAYCDGVFQnETGKNRMKSGSfLSTGWFTMILALELCE 154

                       170       180       190       200
                ....*....|....*....|....*....|....*....|
gi 22122355 334 QVDIY-----EFLPSKRKTDVCY-YHQKFFDSACTMGAYH 367
Cdd:cd23977 155 EILVYgmvsdSYCRNKNHSSVPYhYYEKGRLDECRMYLVH 194
GT29_ST3GAL1_2 cd23966
beta-galactoside alpha-2,3-sialyltransferase 1 and 2; ST3GAL family transfer sialic acid from ...
 167-340 2.17e-15

beta-galactoside alpha-2,3-sialyltransferase 1 and 2; ST3GAL family transfer sialic acid from CMP-Sia to the terminalgalactose residues of glycochains through an 2,3-linkage. ST3GAL1 and 2 preferentially utilize the Galbeta1,3GalNAc on O-glycans of glycoproteins (core1O-glycans) and on glycolipids as an acceptor substrate, respectively. Members ofthis family belong to glycosyltransferase family 29.


Pssm-ID: 467694  Cd Length: 276  Bit Score: 75.78  E-value: 2.17e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 167 PKENFRTKAGPWH--KCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTTIRLVnsqlvttekrflkds 244
Cdd:cd23966  64 PGENPYRTRDPNRcrRCAVVGNSGNLRGSRYGKLIDSHDFVIRMNKAPTKGFEKDVGSKTTHHFM--------------- 128

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 245 lYTEGILILwDPSVYHADIP------QWYQKPdynfFETYKSYRRLHPSQPFYILKPqmpwelwDIIQEISPDLI----- 313
Cdd:cd23966 129 -YPESAVDL-DPGVHLVLVPfkvldlQWLISA----LTTGEITRTYTPVKRFIKADK-------DKVLVINPAFIkyvhd 195

                       170       180       190
                ....*....|....*....|....*....|..
gi 22122355 314 -----QPNPPSSGMLGIIIMMTLCDQVDIYEF 340
Cdd:cd23966 196 nwtehHGRYPSTGFLALIFALHICDEVSVFGF 227
GT29_ST3GAL6 cd23984
beta-galactoside alpha-2,3-sialyltransferase 6; ST3GAL family transfers sialic acid from ...
 180-379 4.63e-14

beta-galactoside alpha-2,3-sialyltransferase 6; ST3GAL family transfers sialic acid from CMP-Sia to the terminal galactose residues of glycochains through an 2,3-linkage. ST3GAL6 utilizes the Galbeta1,4GlcNAc on glycoproteins and glycolipids as an acceptor. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467712  Cd Length: 206  Bit Score: 70.55  E-value: 4.63e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 180 KCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTTIRLVnsqlvttekrflkdslYTEGILIlwDPSVY 259
Cdd:cd23984   4 KCVVVGNGGVLRNKSLGKKIDSYDVIIRMNNGPVIGYENDVGKRTTFRLC----------------YPESIFS--DPSHY 65

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 260 HAD-----IP------QW---------------YQKPDYNFFetYKSY--RRLHPSqpfyILKpQMPWELWDIIQEIsPD 311
Cdd:cd23984  66 DPNttvvlIPfkphdlRWlldllmgkkvsakgfWKKPALNLI--YKPNqiRILNPF----ILR-IAAYELLHFPKRF-PK 137

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 22122355 312 LIQPNPPSSGMLGIIIMMTLCDQVDI----YEFlpSKRKTDVCYYHQKFFdSACTMGAYHPLLFEKNMVKHL 379
Cdd:cd23984 138 EKKPKHPTTGIIAITLALHICNEVHIagfkYDF--SNLNSTLHYYGNETM-SVMTKNEYHNISAEQKFLKDL 206
GT29_ST8SIA_mono cd23971
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 1, 5 and 6; ST8 Sia family members are ...
 166-342 7.32e-14

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 1, 5 and 6; ST8 Sia family members are alpha-N-acetylneuraminidealpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia. The family is subdivided into 3 classes of enzymes, depending on theircatalytic activiy, the mono-STs (ST8Sia1, ST8Sia5 and ST8Sia6), the oligo-ST(ST8Sia3), and the poly-STs (ST8Sia2 and ST8Sia4). The ST8Sia family belongs to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467699  Cd Length: 271  Bit Score: 71.13  E-value: 7.32e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 166 LPKEnFRTKAGPWHKCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTdNFQQDVGTKTTIRLVNSQLVTTEKRFLKDS- 244
Cdd:cd23971  53 LPKE-SPFSNKPLKTCAVVGNGGILKNSSCGREIDSADFVIRCNLPPL-NDSKDVGSKTNLVTANPSILREKFHNLKKRr 130

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 245 -LYTEGILILWDPSVYhadIPQWYQKpdynfFETYKSYRRLHPSQPF------------YILKPQMPWELWDiiqeispd 311
Cdd:cd23971 131 rPFVERMKVYGNALLL---LPAFSYT-----SNTEPSLRALYTLEDFgspqkvlffnpeYLRNLSRYWKSKG-------- 194

                       170       180       190
                ....*....|....*....|....*....|.
gi 22122355 312 lIQPNPPSSGMLGIIIMMTLCDQVDIYEFLP 342
Cdd:cd23971 195 -LKARRLSTGLMLVSAALELCENVHLYGFWP 224
GT29_ST8SIA_poly cd23969
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 2 and 4; ST8Sia2 and 4 are known to be ...
 180-342 1.14e-13

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 2 and 4; ST8Sia2 and 4 are known to be polysialyltransferases, and they can synthesize polysialic acid on neural cell adhesion molecules (NCAMs). ST8Sia family members are alpha-N-acetylneuraminide alpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia and they belong to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467697  Cd Length: 276  Bit Score: 70.91  E-value: 1.14e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 180 KCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTTIRLVNSQLVTTEKRFLKDSLYTEGIL-------- 251
Cdd:cd23969  66 TCAVVGNSGILLNSGCGQEIDSHDFVIRCNLAPVEGYEKDVGTKSNLTTMNPSVIPHAYGDLVNATDKEKFVerlrqlgd 145

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 252 -ILWDP---SVYHADIPQWYQ----KPDYNFFETYKSYRRLHpsqpfyilkpqMPWELWdiiqeiSPDLIQPNPPSSGML 323
Cdd:cd23969 146 sILWIPafvSKGGEEHVQWTNeiilKHKLNVKTAYPPLRLNH-----------AIRGYW------LTTKFRIKRPSTGLL 208

                       170
                ....*....|....*....
gi 22122355 324 GIIIMMTLCDQVDIYEFLP 342
Cdd:cd23969 209 MYTLATRFCDEIHLYGFYP 227
GT29_ST6GALNAC5 cd23976
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; ST6GalNAc family members are ...
 181-373 1.21e-13

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilize Sia2,3Galbeta1,3GalNAc as an acceptor with different individual substrate specificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467704  Cd Length: 244  Bit Score: 70.28  E-value: 1.21e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 181 CAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTTIRLVNSqlvTTEKRFLKD-----SLYTEGILILWD 255
Cdd:cd23976  18 CALVTSSGHLTGSNRGNEIDETECVIRMNDAPTRGYGKDVGNKTSLRVIAH---SSIQRILRNrnellNVSQGTVFIFWG 94

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 256 PSVYhadipqwyQKPD-----YNFFETYKsyRRLHPSQPFYILKPQMPW--ELWDiiQEISPDLIQPNP-PSSGMLGIII 327
Cdd:cd23976  95 PSNY--------MRRDgkglvYNNLQLMN--QILPKLKVYTITRHKMLQfdELFK--RETGKDRKISNTwLSTGWFTMII 162

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 22122355 328 MMTLCDQVDIY-----EFLPSKRKTDVCY-YHQKFFDSACTM---------GAYHPLLFEK 373
Cdd:cd23976 163 ALELCDRINVYgmvppDFCRDPNHPSVPYhYYEPSGPDECTMyishergrkGSHHRFITEK 223
GT29_ST3GAL5 cd23983
beta-galactoside alpha-2,3-sialyltransferase 5; ST3GAL family transfers sialic acid from ...
 180-340 2.91e-13

beta-galactoside alpha-2,3-sialyltransferase 5; ST3GAL family transfers sialic acid from CMP-Sia to the terminalgalactose residues of glycochains through an 2,3-linkage. ST3GAL5 is also known as GM3 ganglioside synthase. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467711  Cd Length: 211  Bit Score: 68.23  E-value: 2.91e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 180 KCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTTIRLVNSQ-LVTTEKRFLKDSLYTEGIL----ILW 254
Cdd:cd23983   4 RCVVVGSGGILHGLELGHLLDQFDIVIRLNNAPVQGYSQDVGNKTTIRMTYPEgAPKSEQEYDPTSLFVAVLFksvdFAW 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 255 DPSVYHADIPQWYQKpdYNFFETYKSYRRLHPSQpFYILKPQmpwelwdIIQEISPDLIQ-PNP-----------PSSGM 322
Cdd:cd23983  84 LKAMVKKEPLSFWSR--LFFWKEVADSIPLKPSQ-FRILNPL-------IIKETALDILQyPEPqsrlwgwdknvPTLGV 153

                       170
                ....*....|....*...
gi 22122355 323 LGIIIMMTLCDQVDIYEF 340
Cdd:cd23983 154 TAVVLATHLCDEVSLAGF 171
GT29_ST8SIA2 cd23987
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 2; ST8Sia2 is a polysialyltransferase ...
 180-359 3.23e-13

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 2; ST8Sia2 is a polysialyltransferase that can synthesize polysialic acid on neural cell adhesion molecules (NCAMs). ST8Sia2 catalyzes shorter polysialic acid formation of NCAMs than ST8Sia4. ST8Sia family members are alpha-N-acetylneuraminide alpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia and they belong to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467715  Cd Length: 278  Bit Score: 69.58  E-value: 3.23e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 180 KCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTTIRLVNSQLVTTEKRFLKDSLYTEGIL-------- 251
Cdd:cd23987  66 TCAIVGNSGILLNSGCGREIDSHDFVIRCNLAPVEEYAKDVGTKTDLVTMNPSVVQRAFEDLVNETWKEKFLqrlqslng 145

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 252 -ILWDPSVYH---ADIPQWYQ----KPDYNFFETYKSYRRLHPSQPFYIlkpqmpwelwdiiqeisPDLIQPNPPSSGML 323
Cdd:cd23987 146 sILWIPAFMAkggEERVEWVNdlilKHHINVRTAYPSLRLLHAVRGYWL-----------------TNKVHIKRPTTGLL 208

                       170       180       190
                ....*....|....*....|....*....|....*...
gi 22122355 324 GIIIMMTLCDQVDIYEFLPSKRKTD--VCYYHqkFFDS 359
Cdd:cd23987 209 MYTLATRFCNRIHLYGFWPFPRDQNqnPVKYH--YYDS 244
GT29_ST3GAL1 cd23980
beta-galactoside alpha-2,3-sialyltransferase 1; ST3GAL family transfer sialic acid from ...
 180-340 6.37e-13

beta-galactoside alpha-2,3-sialyltransferase 1; ST3GAL family transfer sialic acid from CMP-Sia to the terminal galactose residues of glycochains through an 2,3-linkage. ST3GAL1 preferentially utilizes the Galbeta1,3GalNAc on O-glycans of glycoproteins (core1 O-glycans) as an acceptor substrate. Members of this family belong to glycosyltransferase family29 (GT29).


Pssm-ID: 467708  Cd Length: 280  Bit Score: 68.75  E-value: 6.37e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 180 KCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTTIRLVNSQLV---------------TTEKRFLKDS 244
Cdd:cd23980  83 RCAVVGNSGNLKESYYGPQIDSHDFVLRMNKAPTEGFEADVGSKTTHHFVYPESFrelaqnvsmilvpfkTLDLEWVISA 162

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 245 LYTEGILILWDPsvyhadIPqwyqkpdynffetyksyRRLHPSQP-FYILKPQMpwelwdiIQEISPDLIQPNP--PSSG 321
Cdd:cd23980 163 TTTGTISHTYVP------VP-----------------RKIKVKKEkILIYHPAF-------IKYVFDRWLQGHGryPSTG 212

                       170
                ....*....|....*....
gi 22122355 322 MLGIIIMMTLCDQVDIYEF 340
Cdd:cd23980 213 ILSVIFSLHVCDEVDLYGF 231
GT29_ST6GALNAC2L cd23974
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2-like; ST6GalNAc family members are ...
 172-374 1.06e-12

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2-like; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467702  Cd Length: 309  Bit Score: 68.24  E-value: 1.06e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 172 RTKAGPWHKCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKT------TIRLVNSQL-----------V 234
Cdd:cd23974  78 PNGRSPCIRCAVVGNGGILNGSRMGAEIDGHDYVFRVNGAITKGFEKDVGRRTsfytfsTNTLMNSLRayagvgfngppQ 157

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 235 TTEKRFL----KDSLYtegilILWDPSVYHADI---PQWYQKPDYNFFE--TYKSYRRLHPSQPFY---------ILKPQ 296
Cdd:cd23974 158 SKETRYIflpdHDRDY-----LLVKAALTHTPIdrgRDKSKRPSKYFGKdvTAEKFKIYHPDFIRYlrnrflwspILNTK 232

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 22122355 297 MpwelWDIIQeispdliqpnpPSSGMLGIIIMMTLCDQVDIYEFLpskrKTDVCYYHQKFFDSactmgAYHPLLFEKN 374
Cdd:cd23974 233 Q----RDIYR-----------PSTGAVMLLAALHTCDQVSAYGFM----TPDYGKYSDHYYDK-----TYHKVVFYAN 286
GT29_ST6GALNAC1 cd23973
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; ST6GalNAc family members are ...
 180-341 3.79e-12

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc1 utilize mainly GalNAc-,Galbeta1,3GalNAc-, and Sia2,3Galbeta1,3GalNAc on O-glycans of glycoproteins as acceptors. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467701  Cd Length: 309  Bit Score: 66.70  E-value: 3.79e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 180 KCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTTIRLVNSQLVTTEKRFLKDSLYTEgilILWDPSVY 259
Cdd:cd23973  85 RCAVVGNGGILNGSKMGQEIDSHDYVFRVNGAVIKGYEEDVGTRTSFYVHTAHSITSSLMILQKRGFKN---IPQDKDIK 161

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 260 HADIPQWYQkpDYNFFETY--------KSYRRLHPSQPF---------YILKP--------------QMPWELWDIIQei 308
Cdd:cd23973 162 YILFPEGPR--DYQWLEALlknktipsGAYYGRRPRSYFsgdftedkyLVLHPdflryvknrflrskTLKGKYWAIYR-- 237

                       170       180       190
                ....*....|....*....|....*....|...
gi 22122355 309 spdliqpnpPSSGMLGIIIMMTLCDQVDIYEFL 341
Cdd:cd23973 238 ---------PTTGAFLLLTALHLCDTVSAYGFI 261
GT29_ST6GALNAC2 cd23972
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2; ST6GalNAc family members are ...
 158-355 8.49e-12

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc2 utilize mainly GalNAc-,Galbeta1,3GalNAc-, and Sia2,3Galbeta1,3GalNAc on O-glycans of glycoproteins as acceptors. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467700  Cd Length: 308  Bit Score: 65.62  E-value: 8.49e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 158 NTTEWEGYLPKENFRTKAgpwHKCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKT-----TIRLVNSQ 232
Cdd:cd23972  65 NDSANAKLFFPRDTPGKC---IRCAVVGNGGILNGSRQGRAIDAHDYVFRLNGAVIKGFEEDVGTKTsfygfTVNTMKNS 141

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 233 LVTTEKRFLKDSLYTEGILILWDPS-----------VYHADIPQWYQKPD--YNFF---ETYKSYRRLHPSQPFYI---- 292
Cdd:cd23972 142 LISYWNLGFTRTPQGQDLQYIFIPSdirdyvmlrsaILGVPVPEGLDKGDrpHKYFgpeASAKKFKLLHPDFISYLtdrf 221

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 22122355 293 LKPqmpwelwDIIQEISPDLIQpnpPSSGMLGIIIMMTLCDQVDIYEFL-PSKRKTDVCYYHQK 355
Cdd:cd23972 222 LKS-------KLLNTHYGHLYM---PSTGALMLLTALHTCDQVSAYGFItSNYWKFSDHYYERK 275
GT29_ST3GAL3 cd23981
beta-galactoside alpha-2,3-sialyltransferase 3; ST3GAL family transfers sialic acid from ...
 180-340 1.25e-11

beta-galactoside alpha-2,3-sialyltransferase 3; ST3GAL family transfers sialic acid from CMP-Sia to the terminal galactose residues of glycochains through an 2,3-linkage. ST3GAL3 can utilize both Galbeta1,3GlcNAc and Galbeta1,4GlcNAc, mainly on glycoproteins and oligosaccharidesas acceptor substrates, but prefers the Galbeta1,3GlcNAc. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467709  Cd Length: 207  Bit Score: 63.40  E-value: 1.25e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 180 KCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTTIRLVNSQ-LVTTEKRFLKDSLYtegililwdpsV 258
Cdd:cd23981   4 RCIIVGNGGVLANKSLGSKIDDYDVVVRLNSAPVKGFEKDVGSKTTLRITYPEgAIQKPEQYEKDSLF-----------V 72

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 259 YHADIPQwyqkpDYNFFETYKSYRRLHPSQPFY----ILKPQMPWElwdiIQEISPDLIQPN-------PPSSGMLG--- 324
Cdd:cd23981  73 LAGFKWQ-----DFKWLKYIVYKEKVSASDGFWksvaTRVPREPHE----IRILNPYFIQEAafsfiglPFNNGLMGrgn 143

                       170       180
                ....*....|....*....|....
gi 22122355 325 ------IIIMMTL--CDQVDIYEF 340
Cdd:cd23981 144 iptlgsVAITMALhnCDEVAVAGF 167
GT29_ST8SIA4 cd23988
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 4; ST8Sia4 is a polysialyltransferase ...
 167-342 1.79e-11

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 4; ST8Sia4 is a polysialyltransferase that can synthesize polysialic acid on neural cell adhesion molecules (NCAMs). ST8Sia4 catalyzes longer polysialicacid formation of NCAMs than ST8Sia2. ST8Sia family members are alpha-N-acetylneuraminide alpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia and they belong to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467716  Cd Length: 278  Bit Score: 64.21  E-value: 1.79e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 167 PKENFRTKAgpwhkCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTTIRLVNSQLVTTEKRFLKDSLY 246
Cdd:cd23988  58 PMKNRRFKT-----CAVVGNSGILLDSGCGKEIDSHDFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAFGGFRNESD 132

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 247 TEGIL---------ILWDPSVY------HAD-IPQWYQKPDYNFFETYKSYRRLHPSQPFYIlkpqmpwelwdiiqeisP 310
Cdd:cd23988 133 REKFVhrlsmlndsVLWIPAFMvkggekHVEwVNALILKNKLKVRTAYPSLRLIHAVRGYWL-----------------T 195

                       170       180       190
                ....*....|....*....|....*....|..
gi 22122355 311 DLIQPNPPSSGMLGIIIMMTLCDQVDIYEFLP 342
Cdd:cd23988 196 NKVNIKRPSTGLLMYTLATRFCDEIHLYGFWP 227
GT29_ST8SIA6 cd23991
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 6; alpha-N-acetylneuraminide alpha-2, ...
 177-348 3.20e-11

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 6; alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 6 (also known as alpha-2,8-sialyltransferase 8F) prefers O-glycans to N-glycans or glycolipids as acceptor substrates. ST8Sia family members are alpha-N-acetylneuraminide alpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia. The ST8Sia family belongs to glycosyltransferase family 29(GT29).


Pssm-ID: 467719  Cd Length: 273  Bit Score: 63.23  E-value: 3.20e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 177 PWHKCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPT-DNFQQDVGTKTTIRLVNSQLVT------TEKR--FLKD-SLY 246
Cdd:cd23991  63 PYKQCAVVGNGGILKNSSCGAEIDQADFVFRCNLPPTgGNISKDVGSKTNLVTANPSIISikyaklNERRkpFLETvSVY 142

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 247 TEGILILwdpsvyhadiPQWYQKPDYNF-FETYKSYRRLHPSQPFYILKPQMpweLWDIIQEISPDLIQPNPPSSGMLGI 325
Cdd:cd23991 143 GDAFLLL----------PAFSYRSNTALsFKVYYTLEDFKAKQKVIFFHPIY---LKHLAQFWRSKGVQVYRLSTGLMIT 209

                       170       180
                ....*....|....*....|...
gi 22122355 326 IIMMTLCDQVDIYEFLPSKRKTD 348
Cdd:cd23991 210 SAALELCEEVKLYGFWPFSKNTE 232
GT29_ST8SIA5 cd23990
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 5; alpha-N-acetylneuraminide alpha-2, ...
 180-340 5.03e-11

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 5; alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 5 (also known as alpha-2,8-sialyltransferase 8E) is involved in the biosynthesis of gangliosides, such as GD1c, GT1a, GQ1b, and GT3. ST8Sia family members are alpha-N-acetylneuraminide alpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia. The ST8Sia family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467718  Cd Length: 273  Bit Score: 62.93  E-value: 5.03e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 180 KCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAP-TDNFQQDVGTKTTIRLVNSQLVTteKRFLKdslytegiLILWDPSV 258
Cdd:cd23990  66 KCAVVGNGGILKNSKCGREIDSADFVFRCNLPPiSEKYVRDVGVKTDVVTINPSIIT--ERFHK--------LEKWRRPF 135

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 259 YhaDIPQWYQKPD------YNFFETYKSYR------RLHPSQPFYILKPQMpweLWDIIQEISPDLIQPNPPSSGMLGII 326
Cdd:cd23990 136 Y--EVLQVYENASvvlpafYNTRNTDVSIRvkyvldDFESQQAVYYFHPQY---LLNVSRFWLRQGVRAKRISSGLMLVT 210

                       170
                ....*....|....
gi 22122355 327 IMMTLCDQVDIYEF 340
Cdd:cd23990 211 AALELCEEVHLYGF 224
GT29_ST6GALNAC3 cd23975
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; ST6GalNAc family members are ...
 181-256 3.24e-10

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilizeSia2,3Galbeta1,3GalNAc as an acceptor with different individual substrate specificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467703  Cd Length: 226  Bit Score: 59.56  E-value: 3.24e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 181 CAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTTIRLVNSQ----LVTTEKRFLKDSlyTEGILILWDP 256
Cdd:cd23975   4 CAVVSNSGQMVGQKVGAEIDQSSCIWRMNNAPTKGYEEDVGKRTTIRVVSHTsvplLLKNPDYFFKET--NETIYVIWGP 81
GT29_ST8SIA1 cd23989
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 1; Alpha-N-acetylneuraminide alpha-2, ...
 177-369 5.24e-10

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 1; Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 1 (also known as ganglioside GD3 synthase) adds sialic acids to GM3 ganglioside. ST8Sia family members are alpha-N-acetylneuraminide alpha-2,8-sialyltransferases that catalyze analpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia. The ST8Sia family belongs to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467717  Cd Length: 272  Bit Score: 59.84  E-value: 5.24e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 177 PWHKCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAP-TDNFQQDVGTKTTIRLVNSQLVttEKRF----LKDSLYTEGIL 251
Cdd:cd23989  62 PLKKCSVVGNGGILKNSGCGQQIDRADFVMRCNLPPlSREYTDDVGTKTQLVTANPSII--DKRFqnllWSRKSFVESMK 139

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22122355 252 ILWDPSVYhadIPQWYQKPDYN-FFETYKSYRRLHPSQPFYILKPQMpweLWDIIQEISPDLIQPNPPSSGMLGIIIMMT 330
Cdd:cd23989 140 VYGRSYIY---MPAFSMKTGTDpSLRVYYTLADVGANQTVLFANPNF---LRNVGKFWKSKGVHAKRLSTGLFLVSAALG 213

                       170       180       190
                ....*....|....*....|....*....|....*....
gi 22122355 331 LCDQVDIYEFLPSKRKTDVCYYHQKFFDSACTMGAYHPL 369
Cdd:cd23989 214 LCEEVTIYGFWPFSVDLDERTISHHYYDNVLPDSGFHAM 252
GT29_ST3GAL2 cd23979
beta-galactoside alpha-2,3-sialyltransferase 2; ST3GAL family transfer sialic acid from ...
 180-225 1.65e-09

beta-galactoside alpha-2,3-sialyltransferase 2; ST3GAL family transfer sialic acid from CMP-Sia to the terminal galactose residues of glycochains through an 2,3-linkage. ST3GAL2 preferentially utilizes the Galbeta1,3GalNAc on glycolipids as an acceptor substrate. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467707  Cd Length: 279  Bit Score: 58.34  E-value: 1.65e-09
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 22122355 180 KCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGTKTT 225
Cdd:cd23979  82 RCAVVGNSGNLRGSGYGKDIDGHDFIMRMNQAPTVGFEADVGSRTT 127
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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