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Conserved domains on  [gi|226958532|ref|NP_663506|]
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spatacsin [Mus musculus]

Protein Classification

Spatacsin_C domain-containing protein( domain architecture ID 10630385)

Spatacsin_C domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Spatacsin_C pfam14649
Spatacsin C-terminus; This family includes the C-terminus of spatacsin.
2082-2374 9.53e-127

Spatacsin C-terminus; This family includes the C-terminus of spatacsin.


:

Pssm-ID: 464236  Cd Length: 294  Bit Score: 400.83  E-value: 9.53e-127
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226958532  2082 LVGMKLLDKI----PSVPHGELSCTTELLILAHHCFTFTCHMEGITRVLQAARMLTdNHLAPNEEYGLVVRLLTGIGRYN 2157
Cdd:pfam14649    1 LLGNKLLEAAdslgESVPHSELSCIVELLIRAHDCFVLTCSMEGIARVLQAAKHLT-NKLAAEGDYSLLVRLLTGIGRYN 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226958532  2158 EMTYIFDLLHQKHYFEVLMRKKLDPTGTLKTALLDYIKRCRPGDSEKHNMIALCFSMCREIGENHEAAACIQLKLIESQP 2237
Cdd:pfam14649   80 EMTYIFDILIENDQFELLLRKKLDKSNGLKMALLDYLKRCQPEDKEKFNMVALHFSMYREIAELWEEEARTILKKIVSQA 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226958532  2238 WeeSLKDGAQLKQLLLKALTLMLDAAESYAKDSCVRQALHCNRLTKLITLQIHFLNSGqnTMLINLGHQKLMDCIMTLPR 2317
Cdd:pfam14649  160 W--SLKNSPELKKELQKAMENFLDAAESYLKENCLRLAQRCVKQASLVALQLHLLNAG--IRVINLSSSELRQLLVSHPR 235
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 226958532  2318 FYQASIVAEAYDF--VPDWAEVLYQQVILKGDFSYLEEFKQQKLLRPNIFEDISKKYKQ 2374
Cdd:pfam14649  236 FPEALIVAEAYGLntPSDWAEALYNQVVLNGDFEYLEEFKQHLPLTSNLFEDVVKKYKL 294
 
Name Accession Description Interval E-value
Spatacsin_C pfam14649
Spatacsin C-terminus; This family includes the C-terminus of spatacsin.
2082-2374 9.53e-127

Spatacsin C-terminus; This family includes the C-terminus of spatacsin.


Pssm-ID: 464236  Cd Length: 294  Bit Score: 400.83  E-value: 9.53e-127
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226958532  2082 LVGMKLLDKI----PSVPHGELSCTTELLILAHHCFTFTCHMEGITRVLQAARMLTdNHLAPNEEYGLVVRLLTGIGRYN 2157
Cdd:pfam14649    1 LLGNKLLEAAdslgESVPHSELSCIVELLIRAHDCFVLTCSMEGIARVLQAAKHLT-NKLAAEGDYSLLVRLLTGIGRYN 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226958532  2158 EMTYIFDLLHQKHYFEVLMRKKLDPTGTLKTALLDYIKRCRPGDSEKHNMIALCFSMCREIGENHEAAACIQLKLIESQP 2237
Cdd:pfam14649   80 EMTYIFDILIENDQFELLLRKKLDKSNGLKMALLDYLKRCQPEDKEKFNMVALHFSMYREIAELWEEEARTILKKIVSQA 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226958532  2238 WeeSLKDGAQLKQLLLKALTLMLDAAESYAKDSCVRQALHCNRLTKLITLQIHFLNSGqnTMLINLGHQKLMDCIMTLPR 2317
Cdd:pfam14649  160 W--SLKNSPELKKELQKAMENFLDAAESYLKENCLRLAQRCVKQASLVALQLHLLNAG--IRVINLSSSELRQLLVSHPR 235
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 226958532  2318 FYQASIVAEAYDF--VPDWAEVLYQQVILKGDFSYLEEFKQQKLLRPNIFEDISKKYKQ 2374
Cdd:pfam14649  236 FPEALIVAEAYGLntPSDWAEALYNQVVLNGDFEYLEEFKQHLPLTSNLFEDVVKKYKL 294
 
Name Accession Description Interval E-value
Spatacsin_C pfam14649
Spatacsin C-terminus; This family includes the C-terminus of spatacsin.
2082-2374 9.53e-127

Spatacsin C-terminus; This family includes the C-terminus of spatacsin.


Pssm-ID: 464236  Cd Length: 294  Bit Score: 400.83  E-value: 9.53e-127
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226958532  2082 LVGMKLLDKI----PSVPHGELSCTTELLILAHHCFTFTCHMEGITRVLQAARMLTdNHLAPNEEYGLVVRLLTGIGRYN 2157
Cdd:pfam14649    1 LLGNKLLEAAdslgESVPHSELSCIVELLIRAHDCFVLTCSMEGIARVLQAAKHLT-NKLAAEGDYSLLVRLLTGIGRYN 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226958532  2158 EMTYIFDLLHQKHYFEVLMRKKLDPTGTLKTALLDYIKRCRPGDSEKHNMIALCFSMCREIGENHEAAACIQLKLIESQP 2237
Cdd:pfam14649   80 EMTYIFDILIENDQFELLLRKKLDKSNGLKMALLDYLKRCQPEDKEKFNMVALHFSMYREIAELWEEEARTILKKIVSQA 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226958532  2238 WeeSLKDGAQLKQLLLKALTLMLDAAESYAKDSCVRQALHCNRLTKLITLQIHFLNSGqnTMLINLGHQKLMDCIMTLPR 2317
Cdd:pfam14649  160 W--SLKNSPELKKELQKAMENFLDAAESYLKENCLRLAQRCVKQASLVALQLHLLNAG--IRVINLSSSELRQLLVSHPR 235
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 226958532  2318 FYQASIVAEAYDF--VPDWAEVLYQQVILKGDFSYLEEFKQQKLLRPNIFEDISKKYKQ 2374
Cdd:pfam14649  236 FPEALIVAEAYGLntPSDWAEALYNQVVLNGDFEYLEEFKQHLPLTSNLFEDVVKKYKL 294
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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