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Conserved domains on  [gi|21450796|ref|NP_659478|]
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transmembrane protein 106A isoform a [Homo sapiens]

Protein Classification

TMEM106 family protein( domain architecture ID 10537263)

TMEM106 family protein is a DUF1356 domain-containing protein; similar to Homo sapiens transmembrane proteins, 106A and 106B

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF1356 pfam07092
Protein of unknown function (DUF1356); This family consists of several hypothetical mammalian ...
25-252 3.45e-148

Protein of unknown function (DUF1356); This family consists of several hypothetical mammalian proteins of around 250 residues in length. The function of this family is unknown.


:

Pssm-ID: 462088  Cd Length: 232  Bit Score: 413.37  E-value: 3.45e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21450796    25 AIGSKAVNYSSTGSSKSFCSCVPCEGTADASFVTCPTCQGSGKIPQELEKQLVALIPYGDQRLKPKHTKLFVFLAVLICL 104
Cdd:pfam07092   1 AMGSKAASYLSTDNSKPDISQFPYVEFTGRDSVTCPTCQGTGEIPREQENQLVALIPYSDQRLKPRRTKLYVFLSVLICL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21450796   105 VTSSFIVFFLFPRSVIVQPAGLNSSTVAFD--EADIYLNITNILNISNGNYYPIMVTQLTLEVLHLSLVVGQVSNNLLLH 182
Cdd:pfam07092  81 LTSGLIVFFLFPRSIAVQPVGLNSSTVAFDkeERIVYLNITNTLNISNSNYYPVTVTQLTAQVQHMSTVVGQVTLSNLLH 160
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 21450796   183 IGPLASEQMFYAVATKIRDENTY--KICTWLEIKVHHVLLHIQGTLTCSYLSHSEQLVFQSYEYVDCRGNAS 252
Cdd:pfam07092 161 IGPLDSEQMFYTVASRIGDENTYmyKFCTLPKIKVHNIVLHMQGTVTCSYLGHSEQLSFESYEYVDCGGNTT 232
 
Name Accession Description Interval E-value
DUF1356 pfam07092
Protein of unknown function (DUF1356); This family consists of several hypothetical mammalian ...
25-252 3.45e-148

Protein of unknown function (DUF1356); This family consists of several hypothetical mammalian proteins of around 250 residues in length. The function of this family is unknown.


Pssm-ID: 462088  Cd Length: 232  Bit Score: 413.37  E-value: 3.45e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21450796    25 AIGSKAVNYSSTGSSKSFCSCVPCEGTADASFVTCPTCQGSGKIPQELEKQLVALIPYGDQRLKPKHTKLFVFLAVLICL 104
Cdd:pfam07092   1 AMGSKAASYLSTDNSKPDISQFPYVEFTGRDSVTCPTCQGTGEIPREQENQLVALIPYSDQRLKPRRTKLYVFLSVLICL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21450796   105 VTSSFIVFFLFPRSVIVQPAGLNSSTVAFD--EADIYLNITNILNISNGNYYPIMVTQLTLEVLHLSLVVGQVSNNLLLH 182
Cdd:pfam07092  81 LTSGLIVFFLFPRSIAVQPVGLNSSTVAFDkeERIVYLNITNTLNISNSNYYPVTVTQLTAQVQHMSTVVGQVTLSNLLH 160
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 21450796   183 IGPLASEQMFYAVATKIRDENTY--KICTWLEIKVHHVLLHIQGTLTCSYLSHSEQLVFQSYEYVDCRGNAS 252
Cdd:pfam07092 161 IGPLDSEQMFYTVASRIGDENTYmyKFCTLPKIKVHNIVLHMQGTVTCSYLGHSEQLSFESYEYVDCGGNTT 232
PLN03165 PLN03165
chaperone protein dnaJ-related; Provisional
26-75 6.17e-04

chaperone protein dnaJ-related; Provisional


Pssm-ID: 178709 [Multi-domain]  Cd Length: 111  Bit Score: 38.65  E-value: 6.17e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 21450796   26 IGSKAVNYSSTGSSKSFCSCVPCEGtadASFVTCPTCQGSGKIPQELEKQ 75
Cdd:PLN03165  59 VGSGNVTVELGGGEKEVSKCINCDG---AGSLTCTTCQGSGIQPRYLDRR 105
 
Name Accession Description Interval E-value
DUF1356 pfam07092
Protein of unknown function (DUF1356); This family consists of several hypothetical mammalian ...
25-252 3.45e-148

Protein of unknown function (DUF1356); This family consists of several hypothetical mammalian proteins of around 250 residues in length. The function of this family is unknown.


Pssm-ID: 462088  Cd Length: 232  Bit Score: 413.37  E-value: 3.45e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21450796    25 AIGSKAVNYSSTGSSKSFCSCVPCEGTADASFVTCPTCQGSGKIPQELEKQLVALIPYGDQRLKPKHTKLFVFLAVLICL 104
Cdd:pfam07092   1 AMGSKAASYLSTDNSKPDISQFPYVEFTGRDSVTCPTCQGTGEIPREQENQLVALIPYSDQRLKPRRTKLYVFLSVLICL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21450796   105 VTSSFIVFFLFPRSVIVQPAGLNSSTVAFD--EADIYLNITNILNISNGNYYPIMVTQLTLEVLHLSLVVGQVSNNLLLH 182
Cdd:pfam07092  81 LTSGLIVFFLFPRSIAVQPVGLNSSTVAFDkeERIVYLNITNTLNISNSNYYPVTVTQLTAQVQHMSTVVGQVTLSNLLH 160
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 21450796   183 IGPLASEQMFYAVATKIRDENTY--KICTWLEIKVHHVLLHIQGTLTCSYLSHSEQLVFQSYEYVDCRGNAS 252
Cdd:pfam07092 161 IGPLDSEQMFYTVASRIGDENTYmyKFCTLPKIKVHNIVLHMQGTVTCSYLGHSEQLSFESYEYVDCGGNTT 232
PLN03165 PLN03165
chaperone protein dnaJ-related; Provisional
26-75 6.17e-04

chaperone protein dnaJ-related; Provisional


Pssm-ID: 178709 [Multi-domain]  Cd Length: 111  Bit Score: 38.65  E-value: 6.17e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 21450796   26 IGSKAVNYSSTGSSKSFCSCVPCEGtadASFVTCPTCQGSGKIPQELEKQ 75
Cdd:PLN03165  59 VGSGNVTVELGGGEKEVSKCINCDG---AGSLTCTTCQGSGIQPRYLDRR 105
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
43-68 6.00e-03

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 37.43  E-value: 6.00e-03
                         10        20
                 ....*....|....*....|....*....
gi 21450796   43 CSCVPCEGT---ADASFVTCPTCQGSGKI 68
Cdd:PRK10767 143 VTCDTCHGSgakPGTSPKTCPTCHGAGQV 171
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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