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Conserved domains on  [gi|19923056|ref|NP_598615|]
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SNARE-associated protein Snapin [Mus musculus]

Protein Classification

snapin/pallidin family protein( domain architecture ID 10631502)

snapin/pallidin family protein is a component of the BLOC-1 complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Snapin_Pallidin pfam14712
Snapin/Pallidin; This family of proteins includes Snapin, this protein is associated with the ...
 23-110 5.77e-28

Snapin/Pallidin; This family of proteins includes Snapin, this protein is associated with the SNARE complex, which mediates synaptic vesicle docking and fusion. It also includes the yeast snapin-like protein SNN1, which is a part of a complex involved in endosomal cargo sorting. The family also includes pallidin, a component of a complex involved in biogenesis of lysosome-related organelles.


:

Pssm-ID: 464275  Cd Length: 90  Bit Score: 98.42  E-value: 5.77e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19923056    23 DLFAEGLLEFLRPAVQQLDSHVHAVRESQVELREQIDNLATELCRINEDQK--VALDLDPYVKKLLNARRRVVLVNNILQ 100
Cdd:pfam14712   1 DALAEGLLNLLEPVLDELDEKLQELRQSQEELLEQIDRLNEELDELLELQDneMMPDLKPYVKKLVNIKKRMSSLNERLQ 80

                          90
                  ....*....|
gi 19923056   101 NAQERLRRLN 110
Cdd:pfam14712  81 KLQKRALKLQ 90
 
Name Accession Description Interval E-value
Snapin_Pallidin pfam14712
Snapin/Pallidin; This family of proteins includes Snapin, this protein is associated with the ...
 23-110 5.77e-28

Snapin/Pallidin; This family of proteins includes Snapin, this protein is associated with the SNARE complex, which mediates synaptic vesicle docking and fusion. It also includes the yeast snapin-like protein SNN1, which is a part of a complex involved in endosomal cargo sorting. The family also includes pallidin, a component of a complex involved in biogenesis of lysosome-related organelles.


Pssm-ID: 464275  Cd Length: 90  Bit Score: 98.42  E-value: 5.77e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19923056    23 DLFAEGLLEFLRPAVQQLDSHVHAVRESQVELREQIDNLATELCRINEDQK--VALDLDPYVKKLLNARRRVVLVNNILQ 100
Cdd:pfam14712   1 DALAEGLLNLLEPVLDELDEKLQELRQSQEELLEQIDRLNEELDELLELQDneMMPDLKPYVKKLVNIKKRMSSLNERLQ 80

                          90
                  ....*....|
gi 19923056   101 NAQERLRRLN 110
Cdd:pfam14712  81 KLQKRALKLQ 90
 
Name Accession Description Interval E-value
Snapin_Pallidin pfam14712
Snapin/Pallidin; This family of proteins includes Snapin, this protein is associated with the ...
 23-110 5.77e-28

Snapin/Pallidin; This family of proteins includes Snapin, this protein is associated with the SNARE complex, which mediates synaptic vesicle docking and fusion. It also includes the yeast snapin-like protein SNN1, which is a part of a complex involved in endosomal cargo sorting. The family also includes pallidin, a component of a complex involved in biogenesis of lysosome-related organelles.


Pssm-ID: 464275  Cd Length: 90  Bit Score: 98.42  E-value: 5.77e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19923056    23 DLFAEGLLEFLRPAVQQLDSHVHAVRESQVELREQIDNLATELCRINEDQK--VALDLDPYVKKLLNARRRVVLVNNILQ 100
Cdd:pfam14712   1 DALAEGLLNLLEPVLDELDEKLQELRQSQEELLEQIDRLNEELDELLELQDneMMPDLKPYVKKLVNIKKRMSSLNERLQ 80

                          90
                  ....*....|
gi 19923056   101 NAQERLRRLN 110
Cdd:pfam14712  81 KLQKRALKLQ 90
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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