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Conserved domains on  [gi|13624301|ref|NP_112438|]
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cholecystokinin isoform 1 preproprotein [Mus musculus]

Protein Classification

Gastrin domain-containing protein( domain architecture ID 10469077)

Gastrin domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Gastrin pfam00918
Gastrin/cholecystokinin family;
3-115 4.94e-55

Gastrin/cholecystokinin family;


:

Pssm-ID: 459996  Cd Length: 127  Bit Score: 167.26  E-value: 4.94e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13624301     3 SGVCLCVVMAVLAAGALAQPVVPAEATDPVEQRAQE------------APRRQLRAVLRTDG--EPRARLGALLARYIQQ 68
Cdd:pfam00918   1 SGICVCVLLAVLSASCLGQPVSPSHPDGSAVVELEQsltehlrharaaPSSGQLRLLQRLDGnpEQRANLSALLARYIQQ 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 13624301    69 VRKAPSGRMSVLKNLQSLDPSHRISDRDYMGWMDFGRRSAEDYEYPS 115
Cdd:pfam00918  81 ARKGSFGRNSSAGNLQSLDPNHRIKDRDYMGWMDFGRRSAEEYEYSS 127
 
Name Accession Description Interval E-value
Gastrin pfam00918
Gastrin/cholecystokinin family;
3-115 4.94e-55

Gastrin/cholecystokinin family;


Pssm-ID: 459996  Cd Length: 127  Bit Score: 167.26  E-value: 4.94e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13624301     3 SGVCLCVVMAVLAAGALAQPVVPAEATDPVEQRAQE------------APRRQLRAVLRTDG--EPRARLGALLARYIQQ 68
Cdd:pfam00918   1 SGICVCVLLAVLSASCLGQPVSPSHPDGSAVVELEQsltehlrharaaPSSGQLRLLQRLDGnpEQRANLSALLARYIQQ 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 13624301    69 VRKAPSGRMSVLKNLQSLDPSHRISDRDYMGWMDFGRRSAEDYEYPS 115
Cdd:pfam00918  81 ARKGSFGRNSSAGNLQSLDPNHRIKDRDYMGWMDFGRRSAEEYEYSS 127
GASTRIN smart00029
gastrin / cholecystokinin / caerulein family; This family gathers small proteins of about 100 ...
 99-112 6.32e-06

gastrin / cholecystokinin / caerulein family; This family gathers small proteins of about 100 130 amino acids that act as hormones, among them gastrin, cholecystokinin and preprocaerulein which stimulate gastric, biliary, and pancreatic secretion and smooth muscle contraction.


Pssm-ID: 214476  Cd Length: 14  Bit Score: 39.95  E-value: 6.32e-06
                           10
                   ....*....|....
gi 13624301     99 GWMDFGRRSAEDYE 112
Cdd:smart00029   1 GWMDFGRRSAEDDD 14
 
Name Accession Description Interval E-value
Gastrin pfam00918
Gastrin/cholecystokinin family;
3-115 4.94e-55

Gastrin/cholecystokinin family;


Pssm-ID: 459996  Cd Length: 127  Bit Score: 167.26  E-value: 4.94e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13624301     3 SGVCLCVVMAVLAAGALAQPVVPAEATDPVEQRAQE------------APRRQLRAVLRTDG--EPRARLGALLARYIQQ 68
Cdd:pfam00918   1 SGICVCVLLAVLSASCLGQPVSPSHPDGSAVVELEQsltehlrharaaPSSGQLRLLQRLDGnpEQRANLSALLARYIQQ 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 13624301    69 VRKAPSGRMSVLKNLQSLDPSHRISDRDYMGWMDFGRRSAEDYEYPS 115
Cdd:pfam00918  81 ARKGSFGRNSSAGNLQSLDPNHRIKDRDYMGWMDFGRRSAEEYEYSS 127
GASTRIN smart00029
gastrin / cholecystokinin / caerulein family; This family gathers small proteins of about 100 ...
 99-112 6.32e-06

gastrin / cholecystokinin / caerulein family; This family gathers small proteins of about 100 130 amino acids that act as hormones, among them gastrin, cholecystokinin and preprocaerulein which stimulate gastric, biliary, and pancreatic secretion and smooth muscle contraction.


Pssm-ID: 214476  Cd Length: 14  Bit Score: 39.95  E-value: 6.32e-06
                           10
                   ....*....|....
gi 13624301     99 GWMDFGRRSAEDYE 112
Cdd:smart00029   1 GWMDFGRRSAEDDD 14
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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