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Conserved domains on  [gi|58037133|ref|NP_081166|]
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neuroguidin [Mus musculus]

Protein Classification

Sas10/Utp3/C1D family protein( domain architecture ID 10512647)

Sas10/Utp3/C1D family protein may be involved in RNA processing/maturation and/or ribosome biogenesis

Gene Ontology:  GO:0003723

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Sas10_Utp3 pfam04000
Sas10/Utp3/C1D family; This family contains Utp3 and LCP5 which are components of the U3 ...
 18-98 5.39e-14

Sas10/Utp3/C1D family; This family contains Utp3 and LCP5 which are components of the U3 ribonucleoprotein complex. It also includes the human C1D protein and Saccharomyces cerevisiae YHR081W (rrp47), an exosome-associated protein required for the 3' processing of stable RNAs, and Sas10 which has been identified as a regulator of chromatin silencing. This family also includes the human protein Neuroguidin an initiation factor 4E (eIF4E) binding protein.


:

Pssm-ID: 461123  Cd Length: 83  Bit Score: 66.13  E-value: 5.39e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037133    18 LKNLQEQVMAVTAQIQALTTKVRAGTYST--EKGLSFLEVKDQLLLMYLMDLSHLILDKASGASLQGHPAVLRLVEIRTV 95
Cdd:pfam04000   1 LEELKKSLDELEESLEPLLKKVKNPTSKGlsEELPSLLRAKNHLLLAYLINLLFYLLLKLSGVSPKDHPVVKELVRLRVY 80


                  ...
gi 58037133    96 LEK 98
Cdd:pfam04000  81 LEK 83
 
Name Accession Description Interval E-value
Sas10_Utp3 pfam04000
Sas10/Utp3/C1D family; This family contains Utp3 and LCP5 which are components of the U3 ...
 18-98 5.39e-14

Sas10/Utp3/C1D family; This family contains Utp3 and LCP5 which are components of the U3 ribonucleoprotein complex. It also includes the human C1D protein and Saccharomyces cerevisiae YHR081W (rrp47), an exosome-associated protein required for the 3' processing of stable RNAs, and Sas10 which has been identified as a regulator of chromatin silencing. This family also includes the human protein Neuroguidin an initiation factor 4E (eIF4E) binding protein.


Pssm-ID: 461123  Cd Length: 83  Bit Score: 66.13  E-value: 5.39e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037133    18 LKNLQEQVMAVTAQIQALTTKVRAGTYST--EKGLSFLEVKDQLLLMYLMDLSHLILDKASGASLQGHPAVLRLVEIRTV 95
Cdd:pfam04000   1 LEELKKSLDELEESLEPLLKKVKNPTSKGlsEELPSLLRAKNHLLLAYLINLLFYLLLKLSGVSPKDHPVVKELVRLRVY 80


                  ...
gi 58037133    96 LEK 98
Cdd:pfam04000  81 LEK 83
 
Name Accession Description Interval E-value
Sas10_Utp3 pfam04000
Sas10/Utp3/C1D family; This family contains Utp3 and LCP5 which are components of the U3 ...
 18-98 5.39e-14

Sas10/Utp3/C1D family; This family contains Utp3 and LCP5 which are components of the U3 ribonucleoprotein complex. It also includes the human C1D protein and Saccharomyces cerevisiae YHR081W (rrp47), an exosome-associated protein required for the 3' processing of stable RNAs, and Sas10 which has been identified as a regulator of chromatin silencing. This family also includes the human protein Neuroguidin an initiation factor 4E (eIF4E) binding protein.


Pssm-ID: 461123  Cd Length: 83  Bit Score: 66.13  E-value: 5.39e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037133    18 LKNLQEQVMAVTAQIQALTTKVRAGTYST--EKGLSFLEVKDQLLLMYLMDLSHLILDKASGASLQGHPAVLRLVEIRTV 95
Cdd:pfam04000   1 LEELKKSLDELEESLEPLLKKVKNPTSKGlsEELPSLLRAKNHLLLAYLINLLFYLLLKLSGVSPKDHPVVKELVRLRVY 80


                  ...
gi 58037133    96 LEK 98
Cdd:pfam04000  81 LEK 83
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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