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Conserved domains on  [gi|2027432763|ref|NP_065231|]
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blood group Rh(CE) polypeptide isoform 1 [Homo sapiens]

Protein Classification

ammonium transporter family protein( domain architecture ID 518)

ammonium transporter family protein similar to Dictyostelium discoideum ammonium transporter 3 that mediates the import of ammonium in prespore cells

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ammonium_transp super family cl03012
Ammonium Transporter Family;
18-377 3.83e-57

Ammonium Transporter Family;


The actual alignment was detected with superfamily member pfam00909:

Pssm-ID: 445985  Cd Length: 399  Bit Score: 192.51  E-value: 3.83e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2027432763  18 LTLEAALILLFYF---FTHYDASLEDQKGLVA-SYQVGQDL--TVMAALGLGFLTSNFRRHSWSSVAFNLFMLALGVQWA 91
Cdd:pfam00909   1 AFILLSAALVIFMqpgFALLESGLVRSKNVLNiLYKNFQDVaiGVLAYWLFGYSLAFGKRYGFSGFIGNLGVSAAGIQWG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2027432763  92 ILLDG--FLSQFPPGKVVITLFSIRLATMSAMSVLISAGAVLGKVNLAQLVVMVLVEVTALGTLRMVISNIFNTDYHMnl 169
Cdd:pfam00909  81 TLPDGlfFLFQMMFAATAITIVSGAVAERIKFSAYLLFSALLGTLVYPPVAHWVWGEGGWLAKLGVLVDFAGSTVVHI-- 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2027432763 170 rhfyvFAAYFGLTVAWCLPKPLPKGTEDNDQRATIPSLSAMLGALFLWMFWPSVN--SALLRSPIQRKNAMFNTYYALAV 247
Cdd:pfam00909 159 -----FGGYAGLAAALVLGPRIGRFTGKNEAITPHNLPFAVLGTFLLWFGWFGFNagSALTANGRARAIAAVNTNLAAAG 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2027432763 248 SVVTAISGSSLAHpqRKISMTYVHSAVLAGGVAVGTSCHLIpSPWLAMVLGLVAGLISIGGAKCLpvccNRVLGIHHISV 327
Cdd:pfam00909 234 GGLTALLISRLKT--GKPNMLGLANGALAGLVAITPACGVV-TPWGALIIGLIAGVLSVLGYKFL----KEKLGIDDPLD 306

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2027432763 328 MHSIFSLLGLLGEITYIVLLVL-------HTVWNGNGM--IGFQVLLSIGELSLAIVIA 377
Cdd:pfam00909 307 VFPVHGVGGIWGGIAVGIFAAPyvntsgiYGGLLYGNGkqLGVQLIGIAVILAYAFGVT 365
 
Name Accession Description Interval E-value
Ammonium_transp pfam00909
Ammonium Transporter Family;
18-377 3.83e-57

Ammonium Transporter Family;


Pssm-ID: 395729  Cd Length: 399  Bit Score: 192.51  E-value: 3.83e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2027432763  18 LTLEAALILLFYF---FTHYDASLEDQKGLVA-SYQVGQDL--TVMAALGLGFLTSNFRRHSWSSVAFNLFMLALGVQWA 91
Cdd:pfam00909   1 AFILLSAALVIFMqpgFALLESGLVRSKNVLNiLYKNFQDVaiGVLAYWLFGYSLAFGKRYGFSGFIGNLGVSAAGIQWG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2027432763  92 ILLDG--FLSQFPPGKVVITLFSIRLATMSAMSVLISAGAVLGKVNLAQLVVMVLVEVTALGTLRMVISNIFNTDYHMnl 169
Cdd:pfam00909  81 TLPDGlfFLFQMMFAATAITIVSGAVAERIKFSAYLLFSALLGTLVYPPVAHWVWGEGGWLAKLGVLVDFAGSTVVHI-- 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2027432763 170 rhfyvFAAYFGLTVAWCLPKPLPKGTEDNDQRATIPSLSAMLGALFLWMFWPSVN--SALLRSPIQRKNAMFNTYYALAV 247
Cdd:pfam00909 159 -----FGGYAGLAAALVLGPRIGRFTGKNEAITPHNLPFAVLGTFLLWFGWFGFNagSALTANGRARAIAAVNTNLAAAG 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2027432763 248 SVVTAISGSSLAHpqRKISMTYVHSAVLAGGVAVGTSCHLIpSPWLAMVLGLVAGLISIGGAKCLpvccNRVLGIHHISV 327
Cdd:pfam00909 234 GGLTALLISRLKT--GKPNMLGLANGALAGLVAITPACGVV-TPWGALIIGLIAGVLSVLGYKFL----KEKLGIDDPLD 306

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2027432763 328 MHSIFSLLGLLGEITYIVLLVL-------HTVWNGNGM--IGFQVLLSIGELSLAIVIA 377
Cdd:pfam00909 307 VFPVHGVGGIWGGIAVGIFAAPyvntsgiYGGLLYGNGkqLGVQLIGIAVILAYAFGVT 365
AmtB COG0004
Ammonia channel protein AmtB [Inorganic ion transport and metabolism];
209-308 2.05e-09

Ammonia channel protein AmtB [Inorganic ion transport and metabolism];


Pssm-ID: 439775  Cd Length: 413  Bit Score: 58.97  E-value: 2.05e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2027432763 209 AMLGALFLWMFWPSVN--SALLRSPIQrKNAMFNTYYALAVSVVTAISGSSLAHpqRKISMTYVHSAVLAGGVAVGTSCH 286
Cdd:COG0004   206 AALGAFLLWFGWFGFNagSALAANGLA-GLAFVNTNLAAAAGALAWLLVEWLRK--GKPDLLGAANGALAGLVAITPAAG 282

                          90       100
                  ....*....|....*....|..
gi 2027432763 287 LIpSPWLAMVLGLVAGLISIGG 308
Cdd:COG0004   283 FV-SPLGALVIGLIAGVICVFA 303
 
Name Accession Description Interval E-value
Ammonium_transp pfam00909
Ammonium Transporter Family;
18-377 3.83e-57

Ammonium Transporter Family;


Pssm-ID: 395729  Cd Length: 399  Bit Score: 192.51  E-value: 3.83e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2027432763  18 LTLEAALILLFYF---FTHYDASLEDQKGLVA-SYQVGQDL--TVMAALGLGFLTSNFRRHSWSSVAFNLFMLALGVQWA 91
Cdd:pfam00909   1 AFILLSAALVIFMqpgFALLESGLVRSKNVLNiLYKNFQDVaiGVLAYWLFGYSLAFGKRYGFSGFIGNLGVSAAGIQWG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2027432763  92 ILLDG--FLSQFPPGKVVITLFSIRLATMSAMSVLISAGAVLGKVNLAQLVVMVLVEVTALGTLRMVISNIFNTDYHMnl 169
Cdd:pfam00909  81 TLPDGlfFLFQMMFAATAITIVSGAVAERIKFSAYLLFSALLGTLVYPPVAHWVWGEGGWLAKLGVLVDFAGSTVVHI-- 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2027432763 170 rhfyvFAAYFGLTVAWCLPKPLPKGTEDNDQRATIPSLSAMLGALFLWMFWPSVN--SALLRSPIQRKNAMFNTYYALAV 247
Cdd:pfam00909 159 -----FGGYAGLAAALVLGPRIGRFTGKNEAITPHNLPFAVLGTFLLWFGWFGFNagSALTANGRARAIAAVNTNLAAAG 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2027432763 248 SVVTAISGSSLAHpqRKISMTYVHSAVLAGGVAVGTSCHLIpSPWLAMVLGLVAGLISIGGAKCLpvccNRVLGIHHISV 327
Cdd:pfam00909 234 GGLTALLISRLKT--GKPNMLGLANGALAGLVAITPACGVV-TPWGALIIGLIAGVLSVLGYKFL----KEKLGIDDPLD 306

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2027432763 328 MHSIFSLLGLLGEITYIVLLVL-------HTVWNGNGM--IGFQVLLSIGELSLAIVIA 377
Cdd:pfam00909 307 VFPVHGVGGIWGGIAVGIFAAPyvntsgiYGGLLYGNGkqLGVQLIGIAVILAYAFGVT 365
AmtB COG0004
Ammonia channel protein AmtB [Inorganic ion transport and metabolism];
209-308 2.05e-09

Ammonia channel protein AmtB [Inorganic ion transport and metabolism];


Pssm-ID: 439775  Cd Length: 413  Bit Score: 58.97  E-value: 2.05e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2027432763 209 AMLGALFLWMFWPSVN--SALLRSPIQrKNAMFNTYYALAVSVVTAISGSSLAHpqRKISMTYVHSAVLAGGVAVGTSCH 286
Cdd:COG0004   206 AALGAFLLWFGWFGFNagSALAANGLA-GLAFVNTNLAAAAGALAWLLVEWLRK--GKPDLLGAANGALAGLVAITPAAG 282

                          90       100
                  ....*....|....*....|..
gi 2027432763 287 LIpSPWLAMVLGLVAGLISIGG 308
Cdd:COG0004   283 FV-SPLGALVIGLIAGVICVFA 303
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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