|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU-like_RNMTL1 |
cd18106 |
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) ... |
210-402 |
6.74e-84 |
|
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) catalyzes the methylation of 2'-O-ribose residues G1370 to GmG residue of the mitochondrial 16S rRNA. RNMTL1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349979 Cd Length: 148 Bit Score: 253.33 E-value: 6.74e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 210 LLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIINNLEWETVPNYLPPDTRVYVADN 289
Cdd:cd18106 1 LTVICDNIRDPGNLGSILRSAAAAGCSKVLLTKGCVDPWEPKVLRAGAGAHFRLPIYGNLSWDDIPNYLPDDSKVFLADN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 290 cglyaqaemsnkasdhgwvcdqrvmkfhkyeeeedvetgasqdwlpHVEVQSYDS-DWTEAPAAVVIGGETYGVSLESLQ 368
Cdd:cd18106 81 ----------------------------------------------NLPVQPYDSiDYCSGPIVLVIGGETHGVSPEAYK 114
|
170 180 190
....*....|....*....|....*....|....
gi 8922534 369 LAESTGGKRLLIPVVPGVDSLNSAMAASILLFEG 402
Cdd:cd18106 115 LAHSTGGSRVHIPLANGVDSLNSAVAASILLFEM 148
|
|
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
112-409 |
5.61e-53 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 177.70 E-value: 5.61e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 112 KSRPFREKQGKILLEGRRLISDALKAGAVPKMFFFS--RLEYLKELpVDKLK--GVSLIKVKFEDIKDWSDLVTPQGIMG 187
Cdd:COG0566 16 RDKKYREEEGLFLAEGRHAVEEALKAGREIEELLVTegALDRLAEL-LALAKaaGIPVYEVSREVLDKLSGTETHQGVLA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 188 IFAKPDHVKMTYPKTQLQHSlPLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPII- 266
Cdd:COG0566 95 VVRPPEYADLEDLLAEAGEP-PLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVVRASAGALFHVPVAr 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 267 -NNLEwetvpnylppdtrvyvadncglyaqaemsnkasdhgwvcdqRVMKFHKyeeEEDVET-GASqdwlPHVEVQSYDS 344
Cdd:COG0566 174 vTNLA-----------------------------------------DALEELK---EAGFWVvGTD----LDGEASLYEV 205
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 8922534 345 DWTEaPAAVVIGGETYGVSLESLQLAEstggKRLLIPVVPGVDSLNSAMAASILLFEGKRQLRGR 409
Cdd:COG0566 206 DLPG-PVALVLGNEGKGLSRLVLEACD----ELVRIPMAGGVESLNVAVAAAILLYEAARQRRAK 265
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
209-400 |
2.14e-26 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 103.38 E-value: 2.14e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 209 PLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTK-GCVDAWEPKVLRAGMGAHFRMPII--NNLEwETVPNYLPPDTRVY 285
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEpRSADPYNPKAIRASAGALFHLPLVvvDNLE-EALKDLKEAGYAVV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 286 VADncglyaqaemsnkasdhgwvcdqrvmkfhkyeeeedvetGASQDWlphvevqsYDSDWTEaPAAVVIGGETYGVSLE 365
Cdd:pfam00588 80 ATS---------------------------------------LGGKSL--------YEIDFPK-KVALVFGNEGTGLSNE 111
|
170 180 190
....*....|....*....|....*....|....*
gi 8922534 366 SLQLAEstggKRLLIPVVPGVDSLNSAMAASILLF 400
Cdd:pfam00588 112 VLELCD----RLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
200-406 |
1.42e-15 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 75.84 E-value: 1.42e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 200 PKTQLQHSLPLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIInnleweTVPNYlp 279
Cdd:TIGR00186 81 YKTAKSKKQPFLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLA------RVTNL-- 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 280 pdtrvyvadncglyaqAEMSNKASDHG-WVcdqrvmkfhkyeeeedVETGASQDWlphvevQSYDSDWTEaPAAVVIGGE 358
Cdd:TIGR00186 153 ----------------SRTITKLKESGfWT----------------VGTDLDAQD------TLYQVKLTK-PLALVVGNE 193
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 8922534 359 TYGVSLESLQLAEStggkRLLIPVVPGVDSLNSAMAASILLFEGKRQL 406
Cdd:TIGR00186 194 GEGVSRLIKENCDF----LIKIPMAGKVDSLNVSVAAGILLFEIKRQR 237
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
125-191 |
2.35e-09 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 53.31 E-value: 2.35e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 125 LEGRRLISDALKAGAVPKMFFFSRLEYLKELPVDKL---KGVSLIKVKFEDIKDWSDLVTPQGIMGIFAK 191
Cdd:smart00967 1 IEGRHAVEEALKSGRRIKELYLTEGRAERLKELLKLakeRGIKVIEVSKKELDKLSGTANHQGVVAVVKP 70
|
|
| PRK11081 |
PRK11081 |
tRNA guanosine-2'-O-methyltransferase; Provisional |
345-405 |
5.36e-07 |
|
tRNA guanosine-2'-O-methyltransferase; Provisional
Pssm-ID: 236837 [Multi-domain] Cd Length: 229 Bit Score: 50.38 E-value: 5.36e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 8922534 345 DWTEaPAAVVIGGETYGVSLESLQLAEstggKRLLIPVVPGVDSLNSAMAASILLFEGKRQ 405
Cdd:PRK11081 109 DYTR-PTCILMGQEKTGISQEALALAD----QDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
|
|
| TrmL |
COG0219 |
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ... |
335-406 |
3.28e-05 |
|
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ribosomal structure and biogenesis]; tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 439989 Cd Length: 153 Bit Score: 43.87 E-value: 3.28e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 8922534 335 PHVEVQSYDSDWteapaaVVIGGETYGVSLEslqLAESTGGKRLLIPVVPGVDSLNSAMAASILLFEGKRQL 406
Cdd:COG0219 85 PYTDVDYQPGDV------LLFGRETAGLPEE---VLAAPADQRLRIPMRPGVRSLNLSNAVAIVLYEALRQL 147
|
|
| SpoU_sub_bind |
pfam08032 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
124-192 |
1.93e-03 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 429793 [Multi-domain] Cd Length: 74 Bit Score: 36.83 E-value: 1.93e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 8922534 124 LLEGRRLISDALKAGAVPKMFFFSRLEYLKEL-PVDKL---KGVSLIKVKFEDIKDWSDLVTPQGIMGIFAKP 192
Cdd:pfam08032 1 LIYGRHAVLEALKSGPEIKKLYLTEGRRDPRLkELLKLakeRGIKVEEVDRKKLDKLSGTANHQGVVAEVKPY 73
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU-like_RNMTL1 |
cd18106 |
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) ... |
210-402 |
6.74e-84 |
|
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) catalyzes the methylation of 2'-O-ribose residues G1370 to GmG residue of the mitochondrial 16S rRNA. RNMTL1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349979 Cd Length: 148 Bit Score: 253.33 E-value: 6.74e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 210 LLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIINNLEWETVPNYLPPDTRVYVADN 289
Cdd:cd18106 1 LTVICDNIRDPGNLGSILRSAAAAGCSKVLLTKGCVDPWEPKVLRAGAGAHFRLPIYGNLSWDDIPNYLPDDSKVFLADN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 290 cglyaqaemsnkasdhgwvcdqrvmkfhkyeeeedvetgasqdwlpHVEVQSYDS-DWTEAPAAVVIGGETYGVSLESLQ 368
Cdd:cd18106 81 ----------------------------------------------NLPVQPYDSiDYCSGPIVLVIGGETHGVSPEAYK 114
|
170 180 190
....*....|....*....|....*....|....
gi 8922534 369 LAESTGGKRLLIPVVPGVDSLNSAMAASILLFEG 402
Cdd:cd18106 115 LAHSTGGSRVHIPLANGVDSLNSAVAASILLFEM 148
|
|
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
112-409 |
5.61e-53 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 177.70 E-value: 5.61e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 112 KSRPFREKQGKILLEGRRLISDALKAGAVPKMFFFS--RLEYLKELpVDKLK--GVSLIKVKFEDIKDWSDLVTPQGIMG 187
Cdd:COG0566 16 RDKKYREEEGLFLAEGRHAVEEALKAGREIEELLVTegALDRLAEL-LALAKaaGIPVYEVSREVLDKLSGTETHQGVLA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 188 IFAKPDHVKMTYPKTQLQHSlPLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPII- 266
Cdd:COG0566 95 VVRPPEYADLEDLLAEAGEP-PLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVVRASAGALFHVPVAr 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 267 -NNLEwetvpnylppdtrvyvadncglyaqaemsnkasdhgwvcdqRVMKFHKyeeEEDVET-GASqdwlPHVEVQSYDS 344
Cdd:COG0566 174 vTNLA-----------------------------------------DALEELK---EAGFWVvGTD----LDGEASLYEV 205
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 8922534 345 DWTEaPAAVVIGGETYGVSLESLQLAEstggKRLLIPVVPGVDSLNSAMAASILLFEGKRQLRGR 409
Cdd:COG0566 206 DLPG-PVALVLGNEGKGLSRLVLEACD----ELVRIPMAGGVESLNVAVAAAILLYEAARQRRAK 265
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
210-401 |
7.06e-44 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 149.88 E-value: 7.06e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 210 LLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIINNLEWETVPNYLPP-DTRVYVAD 288
Cdd:cd18095 1 LVLVLDGVQDPGNLGTIIRTAAAFGVDGVILSKGTVDPYNPKVVRASMGALFRLPIIRVDDLEELLEELKEaGYKVVAAD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 289 ncglyaqaemsnkasdhgwvcdqrvmkfhkyeeeedvetgasqdwlPHVEVQSYDSDWTEaPAAVVIGGETYGVSLESLQ 368
Cdd:cd18095 81 ----------------------------------------------LDGGSSLYDLDLPK-PVALVLGNEGNGLSDELLE 113
|
170 180 190
....*....|....*....|....*....|...
gi 8922534 369 LAEstggKRLLIPVVPGVDSLNSAMAASILLFE 401
Cdd:cd18095 114 LCD----KRVTIPMSGGVESLNVAVAAAILLYE 142
|
|
| SpoU-like_RNA-MTase |
cd18104 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
210-405 |
5.05e-27 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349977 Cd Length: 146 Bit Score: 104.97 E-value: 5.05e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 210 LLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIINNLEWETVpNYLppdtrvyvadn 289
Cdd:cd18104 1 LILVLEGLEKPGNLGAILRSADAAGADAVILCDPKTDLFNPNVIRASLGAVFTLPVAEASSEETL-AWL----------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 290 cglyaqaemsnkasdhgwvcdqrvmKFHKYeeeedvETGASqdwLPHVEVQSYDSDWTeAPAAVVIGGETYGVSLESLQL 369
Cdd:cd18104 69 -------------------------KENKI------RILAT---TPKAEKLYYEADLR-GPIAIVVGSESEGLSEFWLKA 113
|
170 180 190
....*....|....*....|....*....|....*.
gi 8922534 370 AestgGKRLLIPVVPGVDSLNSAMAASILLFEGKRQ 405
Cdd:cd18104 114 A----DERVRIPMAGQADSLNVSVAAAILLYEALRQ 145
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
209-400 |
2.14e-26 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 103.38 E-value: 2.14e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 209 PLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTK-GCVDAWEPKVLRAGMGAHFRMPII--NNLEwETVPNYLPPDTRVY 285
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEpRSADPYNPKAIRASAGALFHLPLVvvDNLE-EALKDLKEAGYAVV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 286 VADncglyaqaemsnkasdhgwvcdqrvmkfhkyeeeedvetGASQDWlphvevqsYDSDWTEaPAAVVIGGETYGVSLE 365
Cdd:pfam00588 80 ATS---------------------------------------LGGKSL--------YEIDFPK-KVALVFGNEGTGLSNE 111
|
170 180 190
....*....|....*....|....*....|....*
gi 8922534 366 SLQLAEstggKRLLIPVVPGVDSLNSAMAASILLF 400
Cdd:pfam00588 112 VLELCD----RLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| SpoU-like_RNA-MTase |
cd18109 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
210-401 |
2.26e-25 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349982 Cd Length: 141 Bit Score: 100.31 E-value: 2.26e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 210 LLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIINNLEWETVPNyLPPDTRVYVADn 289
Cdd:cd18109 1 LTLALDGIQDPGNLGTIIRTADWFGIRQIICSPDTVDPYNPKVVQASMGSIFRVQIHYTDLPALLAE-LKKAFPVYGAD- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 290 cglyaqaeMsnkasdHGwvcdqrvmkfhkyeeeEDVetgasqdwlphvevqsYDSDWTEaPAAVVIGGETYGVSLESLQL 369
Cdd:cd18109 79 --------L------DG----------------ENL----------------YEFTLPE-KGILVMGNEGHGISPEVLKL 111
|
170 180 190
....*....|....*....|....*....|...
gi 8922534 370 AEstggKRLLIPVVP-GVDSLNSAMAASILLFE 401
Cdd:cd18109 112 LT----HRLTIPRYGkGAESLNVAVATAILLSE 140
|
|
| SpoU-like_family |
cd18082 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
212-401 |
1.01e-22 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349955 Cd Length: 145 Bit Score: 93.44 E-value: 1.01e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 212 LICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPiinnleWETVPNYLpPDTRVYVADNCG 291
Cdd:cd18082 2 LVLDNIRSPGNIGSIFRTADAFGVEKIYLVGPTADIFDPKAKRTSRGTHFSVP------YERVDNFE-EYLKSLKEEGYP 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 292 LYAqaemsnkasdhgwvcdqrvmkfhkyeeeedVETGASQDWLPHVEVQsydsdwTEAPAAVVIGGETYGVSLESLQLAE 371
Cdd:cd18082 75 LIG------------------------------LELTDGSIPLSEFKFK------KPKKIALIFGNERSGLSPELLALCD 118
|
170 180 190
....*....|....*....|....*....|
gi 8922534 372 stggKRLLIPVVPGVDSLNSAMAASILLFE 401
Cdd:cd18082 119 ----YTVHIPMSGKNSSLNVSVATGIALYE 144
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
210-401 |
3.49e-17 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 77.81 E-value: 3.49e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 210 LLLICDNLRDPGNLGTILRSAAGAGCSKVLLTK-GCVDAwEPKVLRAGMGAHFRMPII--NNLEwETVpnylppdtrvyv 286
Cdd:cd18103 1 LLLILDGITDPHNLGAIIRSAEAFGVDGVIIPKrRSAPL-TPTVAKASAGALEHLPIArvTNLA-RAL------------ 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 287 adncglyaqaemsNKASDHG-WV--CDQrvmkfhkyEEEEDVetgasqdwlphvevqsYDSDWTEaPAAVVIGGETYGVS 363
Cdd:cd18103 67 -------------EELKEAGfWIygADG--------EAEKSL----------------YDVDLTG-PLALVLGSEGKGLR 108
|
170 180 190
....*....|....*....|....*....|....*...
gi 8922534 364 LESLQLAEstggKRLLIPVVPGVDSLNSAMAASILLFE 401
Cdd:cd18103 109 RLVLKNCD----FLVKIPMAGKVDSLNVSVAAGIILYE 142
|
|
| SpoU-like_AviRb |
cd18107 |
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes ... |
210-401 |
2.88e-16 |
|
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes methylates the 2'-O atom of U2479 of the 23S ribosomal RNA. AviRb is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349980 Cd Length: 148 Bit Score: 75.50 E-value: 2.88e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 210 LLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIINnlewetVPnylppdtrvyvadn 289
Cdd:cd18107 1 LVVLFDRPTSPGNLGTIIRSADALGAHGLVVTGHAADVYDPKTIRASTGSLFSLPIVR------VP-------------- 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 290 cglyAQAEMSNkasdhgWVCDQRVmkfhKYEEEEDVETGAsqdwlpHVEVQSYDSDWTeAPAAVVIGGETYGVSLESLQL 369
Cdd:cd18107 61 ----SNRELED------WVEARKA----RGTPLQLVGTDE------HGDHQIADHDFT-RPTLLLIGNETAGLSAAWREL 119
|
170 180 190
....*....|....*....|....*....|..
gi 8922534 370 AESTGGkrllIPVVPGVDSLNSAMAASILLFE 401
Cdd:cd18107 120 CDETVS----IPMAGSASSLNAACAASIFLYE 147
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
200-406 |
1.42e-15 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 75.84 E-value: 1.42e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 200 PKTQLQHSLPLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIInnleweTVPNYlp 279
Cdd:TIGR00186 81 YKTAKSKKQPFLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLA------RVTNL-- 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 280 pdtrvyvadncglyaqAEMSNKASDHG-WVcdqrvmkfhkyeeeedVETGASQDWlphvevQSYDSDWTEaPAAVVIGGE 358
Cdd:TIGR00186 153 ----------------SRTITKLKESGfWT----------------VGTDLDAQD------TLYQVKLTK-PLALVVGNE 193
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 8922534 359 TYGVSLESLQLAEStggkRLLIPVVPGVDSLNSAMAASILLFEGKRQL 406
Cdd:TIGR00186 194 GEGVSRLIKENCDF----LIKIPMAGKVDSLNVSVAAGILLFEIKRQR 237
|
|
| SpoU-like |
cd18097 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
210-401 |
4.11e-13 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349970 Cd Length: 144 Bit Score: 66.43 E-value: 4.11e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 210 LLLICDNLRDPGNLGTILRSAAGAGCSKVLLtkgCVDAWEP---KVLRAGMGAHFRMPiinnleWETVPNYLPPdTRVYV 286
Cdd:cd18097 1 LVVVLDNLRSAHNVGSIFRTADAAGVEKIYL---CGYTPTPphpKVAKTALGAEESVP------WEHFEDTLEA-VRALK 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 287 ADNCGLYAqaemsnkasdhgwvcdqrvmkfhkyeeeedVETGA-SQDWlphvevqsYDSDWtEAPAAVVIGGETYGVSLE 365
Cdd:cd18097 71 ARGYTIIA------------------------------LETTEnSVPL--------HEARL-PRPLALVLGNEVRGVSPE 111
|
170 180 190
....*....|....*....|....*....|....*.
gi 8922534 366 SLQLAESTggkrLLIPVVPGVDSLNSAMAASILLFE 401
Cdd:cd18097 112 VLALCDAV----VEIPMFGRKNSLNVAVAAAVALYE 143
|
|
| SpoU-like_MRM1 |
cd18105 |
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose ... |
210-399 |
1.85e-12 |
|
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose residues G1145 to GmG residue of the mitochondrial 16S rRNA. MRM1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349978 Cd Length: 158 Bit Score: 64.85 E-value: 1.85e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 210 LLLicDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPI--INNLewetvpnylppdtrvyva 287
Cdd:cd18105 3 LLL--DEITDPQNLGAILRSAYFLGVDGVVVSSKNSAPLSPVVSKASAGALELMPIysVDNL------------------ 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 288 dncglyaqAEMSNKASDHGW-----VCDQRVMKFHKYeeeedvetgasqdwlphVEVQSYDSDWTEAPAAVVIGGETYGV 362
Cdd:cd18105 63 --------ASFLKSSKENGWkvvgtSAPPSASSDKKT-----------------IPANELSELLLEKPTILVLGNEGRGL 117
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 8922534 363 SLESLQLAESTggkrLLIPV-----VPGVDSLNSAMAASILL 399
Cdd:cd18105 118 RTNIKNLCDYL----VSIPGgrsaeNPGVDSLNVSVAAGILL 155
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
125-191 |
2.35e-09 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 53.31 E-value: 2.35e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 125 LEGRRLISDALKAGAVPKMFFFSRLEYLKELPVDKL---KGVSLIKVKFEDIKDWSDLVTPQGIMGIFAK 191
Cdd:smart00967 1 IEGRHAVEEALKSGRRIKELYLTEGRAERLKELLKLakeRGIKVIEVSKKELDKLSGTANHQGVVAVVKP 70
|
|
| PRK11081 |
PRK11081 |
tRNA guanosine-2'-O-methyltransferase; Provisional |
345-405 |
5.36e-07 |
|
tRNA guanosine-2'-O-methyltransferase; Provisional
Pssm-ID: 236837 [Multi-domain] Cd Length: 229 Bit Score: 50.38 E-value: 5.36e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 8922534 345 DWTEaPAAVVIGGETYGVSLESLQLAEstggKRLLIPVVPGVDSLNSAMAASILLFEGKRQ 405
Cdd:PRK11081 109 DYTR-PTCILMGQEKTGISQEALALAD----QDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
|
|
| SpoU-like_TrmH |
cd18092 |
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group ... |
342-406 |
2.41e-06 |
|
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of the ribose of the universally conserved guanosine 18 (G18) position in tRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349965 Cd Length: 162 Bit Score: 47.08 E-value: 2.41e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 8922534 342 YDSDWTEaPAAVVIGGETYGVSLESLQLAEstggKRLLIPVVPGVDSLNSAMAASILLFEGKRQL 406
Cdd:cd18092 103 DELDYTR-PTALVFGNEKDGVSEEALAAAD----ERVYIPMYGFVESLNVSVAAAIILYELQRQR 162
|
|
| SpoU-like_TrmL |
cd18094 |
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL ... |
335-406 |
1.39e-05 |
|
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349967 Cd Length: 145 Bit Score: 44.75 E-value: 1.39e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 8922534 335 PHVEVQSYDSDWteapaaVVIGGETYGVSLEslqLAESTGGKRLLIPVVPGVDSLNSAMAASILLFEGKRQL 406
Cdd:cd18094 83 PYTDFDFKPGDY------LVFGRESTGLPEE---ILDAFPDRRLRIPMRPKVRSLNLSNSVAIVLYEALRQL 145
|
|
| TrmL |
COG0219 |
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ... |
335-406 |
3.28e-05 |
|
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ribosomal structure and biogenesis]; tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 439989 Cd Length: 153 Bit Score: 43.87 E-value: 3.28e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 8922534 335 PHVEVQSYDSDWteapaaVVIGGETYGVSLEslqLAESTGGKRLLIPVVPGVDSLNSAMAASILLFEGKRQL 406
Cdd:COG0219 85 PYTDVDYQPGDV------LLFGRETAGLPEE---VLAAPADQRLRIPMRPGVRSLNLSNAVAIVLYEALRQL 147
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
205-405 |
6.13e-05 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 44.19 E-value: 6.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 205 QHSLPLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHfrmpiinnlewETVPNYlppdtRV 284
Cdd:PRK11181 91 SLEQPFLLILDGVTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAA-----------ETVPLI-----RV 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8922534 285 yvadncglyaqaemSNKAsdhgwvcdqRVMKFHKYEEEEDVETGASQDwlpHvevQSYDSDWTeAPAAVVIGgetygvsl 364
Cdd:PRK11181 155 --------------TNLA---------RTMRMLQEKNIWIVGTAGEAD---H---TLYQSKLT-GPLALVMG-------- 196
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 8922534 365 eslqlAESTGGKRLL---------IPVVPGVDSLNSAMAASILLFEGKRQ 405
Cdd:PRK11181 197 -----AEGEGMRRLTrehcdelisIPMAGSVSSLNVSVATGICLFEAVRQ 241
|
|
| SpoU_sub_bind |
pfam08032 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
124-192 |
1.93e-03 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 429793 [Multi-domain] Cd Length: 74 Bit Score: 36.83 E-value: 1.93e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 8922534 124 LLEGRRLISDALKAGAVPKMFFFSRLEYLKEL-PVDKL---KGVSLIKVKFEDIKDWSDLVTPQGIMGIFAKP 192
Cdd:pfam08032 1 LIYGRHAVLEALKSGPEIKKLYLTEGRRDPRLkELLKLakeRGIKVEEVDRKKLDKLSGTANHQGVVAEVKPY 73
|
|
| |
