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Conserved domains on  [gi|8394362|ref|NP_058607|]
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sushi-repeat-containing protein SRPX isoform 1 precursor [Mus musculus]

Protein Classification

HYR and DUF4174 domain-containing protein( domain architecture ID 13332197)

protein containing domains HYR, CCP, and DUF4174

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4174 pfam13778
Domain of unknown function (DUF4174); This domain of unknown function is found in a putative ...
 332-451 3.62e-42

Domain of unknown function (DUF4174); This domain of unknown function is found in a putative tumour suppressor gene and in a ligand for the the urokinase-type plasminogen activator receptor, which plays a role in cellular migration and adhesion.


:

Pssm-ID: 463980  Cd Length: 120  Bit Score: 145.47  E-value: 3.62e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8394362    332 LLDQFYEKRRLLIVSTPTARNLLYRLQLGMLQQAQCGLDLRHVTVVELVGVFPTLIGRIRAKIMPPALALQLRLLLRIPL 411
Cdd:pfam13778   1 PLDQFRWKRRLLIISAPSADDPYYRQQLDALQAAECGLAERDLTVIELVGSGPNETGKIEHEQLSPDLIEELRKELGIPR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 8394362    412 YSFSMVVVDKHGMDKERYVSLVTPMALFNLIDTFPLRKEE 451
Cdd:pfam13778  81 NYFSMVLIGKDGGVKERYPAPVSLEALFDLIDAMPMRQQE 120
HYR pfam02494
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ...
 175-257 4.25e-33

HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.


:

Pssm-ID: 460572 [Multi-domain]  Cd Length: 81  Bit Score: 119.80  E-value: 4.25e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8394362    175 VDLEPPRIKCPSVKERIAEPNKLTVRVSWESPEGRDTADGilTDVILKGLPPGSNFPEGDHKIEYTVYDRAENKGTCKFR 254
Cdd:pfam02494   1 VDTTPPTVKCPNNIVRTVELGTSTVRVFFTEPTAFDNSGQ--AILVSRTAQPGDFFPVGTTTVTYVAYDNSGNRASCTFT 78


                  ...
gi 8394362    255 VKV 257
Cdd:pfam02494  79 VTV 81
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 262-317 1.64e-14

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 67.87  E-value: 1.64e-14
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 8394362  262 CGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPSC 317
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 120-175 2.72e-13

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 64.41  E-value: 2.72e-13
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 8394362  120 CPTLTMPANGGFKCVDGAY-FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCV 175
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYsYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 53-175 1.04e-07

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 53.12  E-value: 1.04e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8394362    53 DTPWCSPIKvkygdvyCRAPPG-------GY--YKTAlGTRCDIRCRKGYELHGSSQLICqSNKRWSDKVICKQKRCPTL 123
Cdd:PHA02927 139 EAPICESVK-------CQSPPSisngrhnGYedFYTD-GSVVTYSCNSGYSLIGNSGVLC-SGGEWSDPPTCQIVKCPHP 209

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 8394362   124 TMpANG----GFKcvDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCV 175
Cdd:PHA02927 210 TI-SNGylssGFK--RSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELPKCV 262
 
Name Accession Description Interval E-value
DUF4174 pfam13778
Domain of unknown function (DUF4174); This domain of unknown function is found in a putative ...
 332-451 3.62e-42

Domain of unknown function (DUF4174); This domain of unknown function is found in a putative tumour suppressor gene and in a ligand for the the urokinase-type plasminogen activator receptor, which plays a role in cellular migration and adhesion.


Pssm-ID: 463980  Cd Length: 120  Bit Score: 145.47  E-value: 3.62e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8394362    332 LLDQFYEKRRLLIVSTPTARNLLYRLQLGMLQQAQCGLDLRHVTVVELVGVFPTLIGRIRAKIMPPALALQLRLLLRIPL 411
Cdd:pfam13778   1 PLDQFRWKRRLLIISAPSADDPYYRQQLDALQAAECGLAERDLTVIELVGSGPNETGKIEHEQLSPDLIEELRKELGIPR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 8394362    412 YSFSMVVVDKHGMDKERYVSLVTPMALFNLIDTFPLRKEE 451
Cdd:pfam13778  81 NYFSMVLIGKDGGVKERYPAPVSLEALFDLIDAMPMRQQE 120
HYR pfam02494
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ...
 175-257 4.25e-33

HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.


Pssm-ID: 460572 [Multi-domain]  Cd Length: 81  Bit Score: 119.80  E-value: 4.25e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8394362    175 VDLEPPRIKCPSVKERIAEPNKLTVRVSWESPEGRDTADGilTDVILKGLPPGSNFPEGDHKIEYTVYDRAENKGTCKFR 254
Cdd:pfam02494   1 VDTTPPTVKCPNNIVRTVELGTSTVRVFFTEPTAFDNSGQ--AILVSRTAQPGDFFPVGTTTVTYVAYDNSGNRASCTFT 78


                  ...
gi 8394362    255 VKV 257
Cdd:pfam02494  79 VTV 81
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 262-317 1.64e-14

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 67.87  E-value: 1.64e-14
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 8394362  262 CGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPSC 317
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 120-175 2.72e-13

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 64.41  E-value: 2.72e-13
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 8394362  120 CPTLTMPANGGFKCVDGAY-FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCV 175
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYsYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 262-317 6.23e-13

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 63.31  E-value: 6.23e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 8394362     262 CGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPSC 317
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 120-174 1.42e-12

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 62.16  E-value: 1.42e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 8394362     120 CPTLTMPANGGFKCVDGAY-FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC 174
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYsYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
262-317 3.00e-12

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 61.36  E-value: 3.00e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 8394362    262 CGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPSC 317
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
120-174 6.81e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 49.03  E-value: 6.81e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 8394362    120 CPTLTMPANGGFKCVDGAY-FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC 174
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYnYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 53-175 1.04e-07

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 53.12  E-value: 1.04e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8394362    53 DTPWCSPIKvkygdvyCRAPPG-------GY--YKTAlGTRCDIRCRKGYELHGSSQLICqSNKRWSDKVICKQKRCPTL 123
Cdd:PHA02927 139 EAPICESVK-------CQSPPSisngrhnGYedFYTD-GSVVTYSCNSGYSLIGNSGVLC-SGGEWSDPPTCQIVKCPHP 209

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 8394362   124 TMpANG----GFKcvDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCV 175
Cdd:PHA02927 210 TI-SNGylssGFK--RSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELPKCV 262
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 59-116 4.81e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 43.61  E-value: 4.81e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 8394362   59 PIKVKYGDVYCRAPPggyykTALGTRCDIRCRKGYELHGSSQLICQSNKRWSDKV-ICK 116
Cdd:cd00033   4 PPVPENGTVTGSKGS-----YSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPpTCE 57
PHA02639 PHA02639
EEV host range protein; Provisional
 93-179 7.64e-06

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 47.74  E-value: 7.64e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8394362    93 YELHGSSQLICQSNKRWS-DKVICKQKRC--PTLTMPANGGFKCVDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSG 169
Cdd:PHA02639 121 YSLVGNEKITCIQDKSWKpDPPICKMINCrfPALQNGYINGIPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWFP 200

                         90
                 ....*....|
gi 8394362   170 RPASCVDLEP 179
Cdd:PHA02639 201 SIPTCVRNKP 210
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 59-115 2.43e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 41.74  E-value: 2.43e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 8394362      59 PIKVKYGDVYCRAPPggyykTALGTRCDIRCRKGYELHGSSQLICQSNKRWSDKV-IC 115
Cdd:smart00032   4 PPDIENGTVTSSSGT-----YSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPpTC 56
 
Name Accession Description Interval E-value
DUF4174 pfam13778
Domain of unknown function (DUF4174); This domain of unknown function is found in a putative ...
 332-451 3.62e-42

Domain of unknown function (DUF4174); This domain of unknown function is found in a putative tumour suppressor gene and in a ligand for the the urokinase-type plasminogen activator receptor, which plays a role in cellular migration and adhesion.


Pssm-ID: 463980  Cd Length: 120  Bit Score: 145.47  E-value: 3.62e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8394362    332 LLDQFYEKRRLLIVSTPTARNLLYRLQLGMLQQAQCGLDLRHVTVVELVGVFPTLIGRIRAKIMPPALALQLRLLLRIPL 411
Cdd:pfam13778   1 PLDQFRWKRRLLIISAPSADDPYYRQQLDALQAAECGLAERDLTVIELVGSGPNETGKIEHEQLSPDLIEELRKELGIPR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 8394362    412 YSFSMVVVDKHGMDKERYVSLVTPMALFNLIDTFPLRKEE 451
Cdd:pfam13778  81 NYFSMVLIGKDGGVKERYPAPVSLEALFDLIDAMPMRQQE 120
HYR pfam02494
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ...
 175-257 4.25e-33

HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.


Pssm-ID: 460572 [Multi-domain]  Cd Length: 81  Bit Score: 119.80  E-value: 4.25e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8394362    175 VDLEPPRIKCPSVKERIAEPNKLTVRVSWESPEGRDTADGilTDVILKGLPPGSNFPEGDHKIEYTVYDRAENKGTCKFR 254
Cdd:pfam02494   1 VDTTPPTVKCPNNIVRTVELGTSTVRVFFTEPTAFDNSGQ--AILVSRTAQPGDFFPVGTTTVTYVAYDNSGNRASCTFT 78


                  ...
gi 8394362    255 VKV 257
Cdd:pfam02494  79 VTV 81
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 262-317 1.64e-14

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 67.87  E-value: 1.64e-14
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 8394362  262 CGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPSC 317
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 120-175 2.72e-13

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 64.41  E-value: 2.72e-13
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 8394362  120 CPTLTMPANGGFKCVDGAY-FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCV 175
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYsYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 262-317 6.23e-13

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 63.31  E-value: 6.23e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 8394362     262 CGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPSC 317
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 120-174 1.42e-12

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 62.16  E-value: 1.42e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 8394362     120 CPTLTMPANGGFKCVDGAY-FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC 174
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYsYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
262-317 3.00e-12

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 61.36  E-value: 3.00e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 8394362    262 CGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPSC 317
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
120-174 6.81e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 49.03  E-value: 6.81e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 8394362    120 CPTLTMPANGGFKCVDGAY-FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC 174
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYnYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 53-175 1.04e-07

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 53.12  E-value: 1.04e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8394362    53 DTPWCSPIKvkygdvyCRAPPG-------GY--YKTAlGTRCDIRCRKGYELHGSSQLICqSNKRWSDKVICKQKRCPTL 123
Cdd:PHA02927 139 EAPICESVK-------CQSPPSisngrhnGYedFYTD-GSVVTYSCNSGYSLIGNSGVLC-SGGEWSDPPTCQIVKCPHP 209

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 8394362   124 TMpANG----GFKcvDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCV 175
Cdd:PHA02927 210 TI-SNGylssGFK--RSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELPKCV 262
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 59-116 4.81e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 43.61  E-value: 4.81e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 8394362   59 PIKVKYGDVYCRAPPggyykTALGTRCDIRCRKGYELHGSSQLICQSNKRWSDKV-ICK 116
Cdd:cd00033   4 PPVPENGTVTGSKGS-----YSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPpTCE 57
PHA02639 PHA02639
EEV host range protein; Provisional
 93-179 7.64e-06

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 47.74  E-value: 7.64e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8394362    93 YELHGSSQLICQSNKRWS-DKVICKQKRC--PTLTMPANGGFKCVDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSG 169
Cdd:PHA02639 121 YSLVGNEKITCIQDKSWKpDPPICKMINCrfPALQNGYINGIPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWFP 200

                         90
                 ....*....|
gi 8394362   170 RPASCVDLEP 179
Cdd:PHA02639 201 SIPTCVRNKP 210
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 59-115 2.43e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 41.74  E-value: 2.43e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 8394362      59 PIKVKYGDVYCRAPPggyykTALGTRCDIRCRKGYELHGSSQLICQSNKRWSDKV-IC 115
Cdd:smart00032   4 PPDIENGTVTSSSGT-----YSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPpTC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 93-167 9.50e-04

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 40.69  E-value: 9.50e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8394362    93 YELHGSSQLICQSNKRWS-DKVICKQKRC--PTLT------MPANGGFkcvdgaYFNSRCEYYCSPGYTLKGERTVTCMD 163
Cdd:PHA02817  61 YTLVGEKNIICEKDGKWNkEFPVCKIIRCrfPALQngfvngIPDSKKF------YYESEVSFSCKPGFVLIGTKYSVCGI 134


                 ....
gi 8394362   164 NKAW 167
Cdd:PHA02817 135 NSSW 138
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 48-175 1.64e-03

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 40.45  E-value: 1.64e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 8394362    48 HSLYKDTPWCSPIKVKYgdvycrappggyyktALGTRCDIRCRKGYELHGSSQLICQSNKrWSDKVICKQK-RCPTLTmp 126
Cdd:PHA02954 131 QPLQLEHGSCQPVKEKY---------------SFGEHITINCDVGYEVIGASYISCTANS-WNVIPSCQQKcDIPSLS-- 192

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 8394362   127 aNGgfkCVDGAYFN--SRCEYYCSPGYTLKGERTVTCMDNKaWSGRPASCV 175
Cdd:PHA02954 193 -NG---LISGSTFSigGVIHLSCKSGFTLTGSPSSTCIDGK-WNPVLPICV 238
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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