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Conserved domains on  [gi|158749553|ref|NP_038679|]
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splicing factor 3A subunit 2 [Mus musculus]

Protein Classification

PRP11 family protein( domain architecture ID 711366)

PRP11 family protein similar to Dictyostelium discoideum splicing factor 3A subunit 2 which is involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex

CATH:  2.60.40.2690
Gene Ontology:  GO:0000398|GO:0008270|GO:0003676|GO:0000245

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRP11 super family cl25587
Splicing factor 3a, subunit 2 [RNA processing and modification];
1-217 6.25e-75

Splicing factor 3a, subunit 2 [RNA processing and modification];


The actual alignment was detected with superfamily member COG5246:

Pssm-ID: 227571 [Multi-domain]  Cd Length: 222  Bit Score: 234.95  E-value: 6.25e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553   1 MDFQHRPGGKTGSGGVASSSESNRDRRERLRQLALETIDINKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQT 80
Cdd:COG5246    1 MNYGGRGGSKTGGGGTASEIKKNKKRRSRQLLLEAYGQDLMDDPYLSKNHTGKYVCLLCKTKHLTEMSYVKHREGKKHKE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  81 NLARRAAKEAKEAPA-QPA-----PEKVKVEVKKFVKIGRPGYKVTKQRDTEMGQQSLLFQIDYPEIAEGIMPRHRFMSA 154
Cdd:COG5246   81 NSSRRSEEKSSLGREnQTThdfrqQQKIIEAKQSLKRSGIPSYKVRSLVEPKGGRRGLGIQVNYEDDLAEEMPQYRIVSS 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 158749553 155 YEQRIEPPDRRWQYLLMAAEPYETIAFKvpsreIDKAEGKFW---THWNRETKQFFLQFHFKMEKP 217
Cdd:COG5246  161 LEQNVEEYDESFRYLVFACEPYENIAFK-----FENKEIDFLsiyEDWDAETGTYTLQFFFLEAGP 221
PRK12323 super family cl46901
DNA polymerase III subunit gamma/tau;
324-449 4.44e-09

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK14951:

Pssm-ID: 481241 [Multi-domain]  Cd Length: 618  Bit Score: 58.96  E-value: 4.44e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 324 PPAPGVHPPTPGVhPPAPGVHPPAPGVHPPAPgvHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPgVHPP 403
Cdd:PRK14951 373 AAPAEKKTPARPE-AAAPAAAPVAQAAAAPAP--AAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAA-VALA 448

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 158749553 404 APAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPG 449
Cdd:PRK14951 449 PAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEG 494
 
Name Accession Description Interval E-value
PRP11 COG5246
Splicing factor 3a, subunit 2 [RNA processing and modification];
1-217 6.25e-75

Splicing factor 3a, subunit 2 [RNA processing and modification];


Pssm-ID: 227571 [Multi-domain]  Cd Length: 222  Bit Score: 234.95  E-value: 6.25e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553   1 MDFQHRPGGKTGSGGVASSSESNRDRRERLRQLALETIDINKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQT 80
Cdd:COG5246    1 MNYGGRGGSKTGGGGTASEIKKNKKRRSRQLLLEAYGQDLMDDPYLSKNHTGKYVCLLCKTKHLTEMSYVKHREGKKHKE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  81 NLARRAAKEAKEAPA-QPA-----PEKVKVEVKKFVKIGRPGYKVTKQRDTEMGQQSLLFQIDYPEIAEGIMPRHRFMSA 154
Cdd:COG5246   81 NSSRRSEEKSSLGREnQTThdfrqQQKIIEAKQSLKRSGIPSYKVRSLVEPKGGRRGLGIQVNYEDDLAEEMPQYRIVSS 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 158749553 155 YEQRIEPPDRRWQYLLMAAEPYETIAFKvpsreIDKAEGKFW---THWNRETKQFFLQFHFKMEKP 217
Cdd:COG5246  161 LEQNVEEYDESFRYLVFACEPYENIAFK-----FENKEIDFLsiyEDWDAETGTYTLQFFFLEAGP 221
SF3A2 pfam16835
Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11); SF3A2 is one of the components of the ...
 113-206 2.30e-57

Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11); SF3A2 is one of the components of the SF3a splicing factor complex of the mature U2 snRNP (small nuclear ribonucleoprotein particle). In yeast, SF3a shows a bifurcated assembly structure of three subunits, Prp9 (subunit 3), Prp11 (subunit 2) and Prp21 (subunit 1). with Prp21 wrapping around Prp11.


Pssm-ID: 435601  Cd Length: 95  Bit Score: 185.05  E-value: 2.30e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  113 GRPGYKVTKQRDTEMGQQSLLFQIDYPEIAEGIMPRHRFMSAYEQRIE-PPDRRWQYLLMAAEPYETIAFKVPSREIDKA 191
Cdd:pfam16835   1 GRPGYKVTKVRDPETGQLGLLFQVDYPEIAEGVKPRHRIMSAYEQKVEtPPDKNYQYLVIAAEPYETIAFKIPNREIDRL 80

                          90
                  ....*....|....*
gi 158749553  192 EGKFWTHWNRETKQF 206
Cdd:pfam16835  81 EGKFWTYWDPDTKEF 95
CactinC_cactus smart01050
Cactus-binding C-terminus of cactin protein; CactinC_cactus is the C-terminal 200 residues of ...
 112-218 4.77e-28

Cactus-binding C-terminus of cactin protein; CactinC_cactus is the C-terminal 200 residues of the cactin protein which are necessary for the association of cactin with IkappaB-cactus as one of the intracellular members of the Rel complex. The Rel (NF-kappaB) pathway is conserved in invertebrates and vertebrates. In mammals, it controls the activities of the immune and inflammatory response genes as well as viral genes, and is critical for cell growth and survival. In Drosophila, the Rel pathway functions in the innate cellular and humoral immune response, in muscle development, and in the establishment of dorsal-ventral polarity in the early embryo. Most members of the family also have a Cactin_mid domain further upstream.


Pssm-ID: 214996  Cd Length: 129  Bit Score: 108.21  E-value: 4.77e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553   112 IGRPGYKVTK---QRDTEMGQQSLLFQIDYPE-IAEGIMPRHRFMSAYEQriEPPDRRWQYLLM-AAEPYETIAFKVPSR 186
Cdd:smart01050  20 YDWNKYNQTHydnDNPPPKIVQGYKFNIFYPDlIDKGKAPRYRIESSFEI--EKPDDDTCLLRFsAGPPYEDIAFKIVNR 97

                           90       100       110
                   ....*....|....*....|....*....|...
gi 158749553   187 EIDKAE-GKFWTHWNRetKQFFLQFHFKMEKPP 218
Cdd:smart01050  98 EWDYSHrGGFKSSFDN--GILQLQFNFKKTRYR 128
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 324-449 4.44e-09

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 58.96  E-value: 4.44e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 324 PPAPGVHPPTPGVhPPAPGVHPPAPGVHPPAPgvHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPgVHPP 403
Cdd:PRK14951 373 AAPAEKKTPARPE-AAAPAAAPVAQAAAAPAP--AAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAA-VALA 448

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 158749553 404 APAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPG 449
Cdd:PRK14951 449 PAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEG 494
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 324-447 1.55e-07

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 53.89  E-value: 1.55e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  324 PPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPP 403
Cdd:pfam09770 212 QQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTILQRPQSPQPDPAQPSIQPQAQQFHQQ 291

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  404 APAVHP------QAPGVHPPAPGIHPQ--APGVHPQPPPGVHPAAPG--------VHPQP 447
Cdd:pfam09770 292 PPPVPVqptqilQNPNRLSAARVGYPQnpQPGVQPAPAHQAHRQQGSfgrqapiiTHPQQ 351
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 322-447 3.24e-03

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 40.14  E-value: 3.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 322 VHPPAPGVHPPTPGVHPPAPGVHP-PAPGVHPPAPGVHP----PTPGVHP----PAPGVHP----PAPGVHPPAPGVHPP 388
Cdd:NF033839 307 KKEVKPEPETPKPEVKPQLEKPKPeVKPQPEKPKPEVKPqletPKPEVKPqpekPKPEVKPqpekPKPEVKPQPETPKPE 386

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 158749553 389 PSAGVHPQAPGVHP----PAPAVHPQ--------APGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQP 447
Cdd:NF033839 387 VKPQPEKPKPEVKPqpekPKPEVKPQpekpkpevKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQP 457
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 322-455 5.65e-03

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 38.98  E-value: 5.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 322 VHPPAPGVHPPTP-GVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVH-----PPAPGVHPPAPGVHPPPSAGVHP 395
Cdd:NF040712 202 VPRLAREPADARPeEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEqpedePVGPGAAPAAEPDEATRDAGEPP 281

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 396 qAPGVHPPAPAVHPQAPGVHPPAPgihPQAPGVHPQPPPGVHPAAPgvhPQPPGVHPSNP 455
Cdd:NF040712 282 -APGAAETPEAAEPPAPAPAAPAA---PAAPEAEEPARPEPPPAPK---PKRRRRRASVP 334
 
Name Accession Description Interval E-value
PRP11 COG5246
Splicing factor 3a, subunit 2 [RNA processing and modification];
1-217 6.25e-75

Splicing factor 3a, subunit 2 [RNA processing and modification];


Pssm-ID: 227571 [Multi-domain]  Cd Length: 222  Bit Score: 234.95  E-value: 6.25e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553   1 MDFQHRPGGKTGSGGVASSSESNRDRRERLRQLALETIDINKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQT 80
Cdd:COG5246    1 MNYGGRGGSKTGGGGTASEIKKNKKRRSRQLLLEAYGQDLMDDPYLSKNHTGKYVCLLCKTKHLTEMSYVKHREGKKHKE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  81 NLARRAAKEAKEAPA-QPA-----PEKVKVEVKKFVKIGRPGYKVTKQRDTEMGQQSLLFQIDYPEIAEGIMPRHRFMSA 154
Cdd:COG5246   81 NSSRRSEEKSSLGREnQTThdfrqQQKIIEAKQSLKRSGIPSYKVRSLVEPKGGRRGLGIQVNYEDDLAEEMPQYRIVSS 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 158749553 155 YEQRIEPPDRRWQYLLMAAEPYETIAFKvpsreIDKAEGKFW---THWNRETKQFFLQFHFKMEKP 217
Cdd:COG5246  161 LEQNVEEYDESFRYLVFACEPYENIAFK-----FENKEIDFLsiyEDWDAETGTYTLQFFFLEAGP 221
SF3A2 pfam16835
Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11); SF3A2 is one of the components of the ...
 113-206 2.30e-57

Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11); SF3A2 is one of the components of the SF3a splicing factor complex of the mature U2 snRNP (small nuclear ribonucleoprotein particle). In yeast, SF3a shows a bifurcated assembly structure of three subunits, Prp9 (subunit 3), Prp11 (subunit 2) and Prp21 (subunit 1). with Prp21 wrapping around Prp11.


Pssm-ID: 435601  Cd Length: 95  Bit Score: 185.05  E-value: 2.30e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  113 GRPGYKVTKQRDTEMGQQSLLFQIDYPEIAEGIMPRHRFMSAYEQRIE-PPDRRWQYLLMAAEPYETIAFKVPSREIDKA 191
Cdd:pfam16835   1 GRPGYKVTKVRDPETGQLGLLFQVDYPEIAEGVKPRHRIMSAYEQKVEtPPDKNYQYLVIAAEPYETIAFKIPNREIDRL 80

                          90
                  ....*....|....*
gi 158749553  192 EGKFWTHWNRETKQF 206
Cdd:pfam16835  81 EGKFWTYWDPDTKEF 95
CactinC_cactus smart01050
Cactus-binding C-terminus of cactin protein; CactinC_cactus is the C-terminal 200 residues of ...
 112-218 4.77e-28

Cactus-binding C-terminus of cactin protein; CactinC_cactus is the C-terminal 200 residues of the cactin protein which are necessary for the association of cactin with IkappaB-cactus as one of the intracellular members of the Rel complex. The Rel (NF-kappaB) pathway is conserved in invertebrates and vertebrates. In mammals, it controls the activities of the immune and inflammatory response genes as well as viral genes, and is critical for cell growth and survival. In Drosophila, the Rel pathway functions in the innate cellular and humoral immune response, in muscle development, and in the establishment of dorsal-ventral polarity in the early embryo. Most members of the family also have a Cactin_mid domain further upstream.


Pssm-ID: 214996  Cd Length: 129  Bit Score: 108.21  E-value: 4.77e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553   112 IGRPGYKVTK---QRDTEMGQQSLLFQIDYPE-IAEGIMPRHRFMSAYEQriEPPDRRWQYLLM-AAEPYETIAFKVPSR 186
Cdd:smart01050  20 YDWNKYNQTHydnDNPPPKIVQGYKFNIFYPDlIDKGKAPRYRIESSFEI--EKPDDDTCLLRFsAGPPYEDIAFKIVNR 97

                           90       100       110
                   ....*....|....*....|....*....|...
gi 158749553   187 EIDKAE-GKFWTHWNRetKQFFLQFHFKMEKPP 218
Cdd:smart01050  98 EWDYSHrGGFKSSFDN--GILQLQFNFKKTRYR 128
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 324-449 4.44e-09

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 58.96  E-value: 4.44e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 324 PPAPGVHPPTPGVhPPAPGVHPPAPGVHPPAPgvHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPgVHPP 403
Cdd:PRK14951 373 AAPAEKKTPARPE-AAAPAAAPVAQAAAAPAP--AAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAA-VALA 448

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 158749553 404 APAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPG 449
Cdd:PRK14951 449 PAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEG 494
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 52-85 1.59e-08

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 50.33  E-value: 1.59e-08
                           10        20        30
                   ....*....|....*....|....*....|....
gi 158749553    52 GSYECKLCLTLHNNEGSYLAHTQGKKHQTNLARR 85
Cdd:smart00451   2 GGFYCKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 324-456 7.78e-08

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 54.72  E-value: 7.78e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 324 PPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPgvhppapgvhpppsagvhpqapgvHPP 403
Cdd:PRK14951 386 AAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAP------------------------AAA 441

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 158749553 404 APAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPGVHPSNPG 456
Cdd:PRK14951 442 PAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEG 494
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 324-447 1.55e-07

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 53.89  E-value: 1.55e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  324 PPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPP 403
Cdd:pfam09770 212 QQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTILQRPQSPQPDPAQPSIQPQAQQFHQQ 291

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  404 APAVHP------QAPGVHPPAPGIHPQ--APGVHPQPPPGVHPAAPG--------VHPQP 447
Cdd:pfam09770 292 PPPVPVqptqilQNPNRLSAARVGYPQnpQPGVQPAPAHQAHRQQGSfgrqapiiTHPQQ 351
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 338-458 2.03e-07

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 53.50  E-value: 2.03e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  338 PPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQAPGVHPP 417
Cdd:pfam09770 212 QQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTILQRPQSPQPDPAQPSIQPQAQQFHQQ 291

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 158749553  418 APGIHPQ--------------APGVHPQPPPGVHPAAPGVHPQPPGVHPSNPGVH 458
Cdd:pfam09770 292 PPPVPVQptqilqnpnrlsaaRVGYPQNPQPGVQPAPAHQAHRQQGSFGRQAPII 346
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 323-449 2.29e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 53.45  E-value: 2.29e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 323 HPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPtpgvhPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHP 402
Cdd:PRK07764 385 LGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAA-----PAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPA 459

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 158749553 403 PAPAVHPqAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPG 449
Cdd:PRK07764 460 AAPSAQP-APAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAG 505
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 304-425 6.23e-07

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 51.49  E-value: 6.23e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 304 PAPGVHPPAPVVHPPTSGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAP 383
Cdd:PTZ00436 222 PAKAAAAPAKAAAPPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAAPAK 301

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 158749553 384 GVHPPPSAGVHPqAPGVHPPAPAVHPQAPGVHPPAPGIHPQA 425
Cdd:PTZ00436 302 AAAAPAKAAAAP-AKAAAPPAKAAAPPAKAATPPAKAAAPPA 342
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 289-448 3.11e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 49.98  E-value: 3.11e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 289 PPAPVVHPPTSGvhPPAPGVHPPAPVVHPPTSGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPA 368
Cdd:PRK07764 621 PAAPAAPAPAGA--AAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAP 698

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 369 PGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQAPGvHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPP 448
Cdd:PRK07764 699 AQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPP-EPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPS 777
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 54-78 3.36e-06

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 43.25  E-value: 3.36e-06
                          10        20
                  ....*....|....*....|....*
gi 158749553   54 YECKLCLTLHNNEGSYLAHTQGKKH 78
Cdd:pfam12874   1 FYCELCNVTFNSESQLKSHLQGKKH 25
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 304-458 3.36e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 49.60  E-value: 3.36e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 304 PAPGVHPPAPVVHPPTSGVHPPAPGVHPPTPGVHPPApgvHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAP 383
Cdd:PRK07764 615 PAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPE---HHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPA 691

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 158749553 384 GVHPPPSAGVHPQAPGVHPPAPAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGvHPAAPGVHPQPPGVHPSNPGVH 458
Cdd:PRK07764 692 APAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPP-EPDDPPDPAGAPAQPPPPPAPA 765
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 324-438 4.25e-06

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 48.79  E-value: 4.25e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 324 PPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPqAPGVHPP 403
Cdd:PTZ00436 235 PPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAAPAKAAAAP-AKAAAAP 313

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 158749553 404 APAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHP 438
Cdd:PTZ00436 314 AKAAAPPAKAAAPPAKAATPPAKAAAPPAKAAAAP 348
PHA03247 PHA03247
large tegument protein UL36; Provisional
 298-448 8.43e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.78  E-value: 8.43e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  298 TSGVHPPAPGVHPPAPVVHPPTSGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPG 377
Cdd:PHA03247 2696 TSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAP 2775

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 158749553  378 VHPPAPGVHPPPSAGVHPQAPGV-HPPAPAVHPQApgVHPPAPGIHPQAPGVHPQPPP-GVHPAAPGVHPQPP 448
Cdd:PHA03247 2776 AAGPPRRLTRPAVASLSESRESLpSPWDPADPPAA--VLAPAAALPPAASPAGPLPPPtSAQPTAPPPPPGPP 2846
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 289-447 1.02e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 48.06  E-value: 1.02e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 289 PPAPVVHPPTSGVHPPAPGVHPPAPVVHPPTSGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPA 368
Cdd:PRK07764 635 APAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQA 714

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 369 PGVHPPAPGVHPPAPGVHPPPSAGV----HPQAPGVHPPAPAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVH 444
Cdd:PRK07764 715 DDPAAQPPQAAQGASAPSPAADDPVplppEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMD 794


                 ...
gi 158749553 445 PQP 447
Cdd:PRK07764 795 DED 797
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 303-413 1.48e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 47.40  E-value: 1.48e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 303 PPAPGVHPPAPVVHPPTSGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPA 382
Cdd:PRK14951 384 PEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPPAQAAPETVAIP 463

                         90       100       110
                 ....*....|....*....|....*....|.
gi 158749553 383 PGVHPPPSAGVHPQAPGVHPPAPAVHPQAPG 413
Cdd:PRK14951 464 VRVAPEPAVASAAPAPAAAPAAARLTPTEEG 494
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 324-478 1.79e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 47.29  E-value: 1.79e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 324 PPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPP 403
Cdd:PRK07764 600 PPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPA 679

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 158749553 404 APAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPGVHPSNP---GVHPAPMPPMLRPPLPSDGPGNM 478
Cdd:PRK07764 680 APPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPspaADDPVPLPPEPDDPPDPAGAPAQ 757
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 325-457 2.01e-05

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 47.39  E-value: 2.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  325 PAPGVHPPTPgVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPA 404
Cdd:PRK10263  362 PVPGPQTGEP-VIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQ 440

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 158749553  405 PAVHPQApgvHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPGVHPSNPGV 457
Cdd:PRK10263  441 PVAGNAW---QAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVV 490
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 323-458 2.05e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 47.17  E-value: 2.05e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 323 HPPAPGVHPPTPGVH-PPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVH 401
Cdd:PRK07994 360 HPAAPLPEPEVPPQSaAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAK 439

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 158749553 402 PPAPAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPGVHPSNPGVH 458
Cdd:PRK07994 440 KSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVAT 496
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 298-425 2.64e-05

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 46.83  E-value: 2.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  298 TSGVHPPAPGVHPPapvvhppTSGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPG 377
Cdd:pfam05109 482 TSGASPVTPSPSPR-------DNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTPNATSPTLGKTSPTSAVTTPTPN 554

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 158749553  378 VHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQAPGVHPPAPGIHPQA 425
Cdd:pfam05109 555 ATSPTPAVTTPTPNATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQA 602
PHA03247 PHA03247
large tegument protein UL36; Provisional
 303-455 5.64e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.08  E-value: 5.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  303 PPAPGVHPPAPVVHPPTSGVHPPAPGvhPPTPGVHP-PAPGVHPPAPGVHPPAPGVHPPTPGVH-PPAPGVHPPAPGVHP 380
Cdd:PHA03247 2775 PAAGPPRRLTRPAVASLSESRESLPS--PWDPADPPaAVLAPAAALPPAASPAGPLPPPTSAQPtAPPPPPGPPPPSLPL 2852

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 158749553  381 PAPGVHPPPSAGVHPQAPGVHPPAPAVHPQAPGVHPPAPgihPQAPGVHPQPPPGVHPAAPGVHPQPPGVHPSNP 455
Cdd:PHA03247 2853 GGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAV---SRSTESFALPPDQPERPPQPQAPPPPQPQPQPP 2924
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 325-449 6.60e-05

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 44.94  E-value: 6.60e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 325 PAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVhpqAPGVHPPA 404
Cdd:PTZ00436 229 PAKAAAPPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAA---APAKAAAA 305

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 158749553 405 PAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPG 449
Cdd:PTZ00436 306 PAKAAAAPAKAAAPPAKAAAPPAKAATPPAKAAAPPAKAAAAPVG 350
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
303-455 1.28e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 44.48  E-value: 1.28e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 303 PPAPGVHPPAPVVHPPTSGVHPPAPGVHPPT--------PGVHPPAPGVHP-PAPGVHPPAPGVHPPtPGVHPPAPGVHP 373
Cdd:PRK12323 406 PAAAPAAAAAARAVAAAPARRSPAPEALAAArqasargpGGAPAPAPAPAAaPAAAARPAAAGPRPV-AAAAAAAPARAA 484

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 374 PAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPGVHPS 453
Cdd:PRK12323 485 PAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPR 564


                 ..
gi 158749553 454 NP 455
Cdd:PRK12323 565 PP 566
PHA03247 PHA03247
large tegument protein UL36; Provisional
 324-455 1.82e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.54  E-value: 1.82e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  324 PPAPGVHPPTPGVhpPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPP 403
Cdd:PHA03247 2707 TPEPAPHALVSAT--PLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT 2784

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 158749553  404 APAVHPQAPGVH----PPAPGIHPQA-PGVHPQPPPGVHPAAPgvHPQPPGVHPSNP 455
Cdd:PHA03247 2785 RPAVASLSESREslpsPWDPADPPAAvLAPAAALPPAASPAGP--LPPPTSAQPTAP 2839
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 325-453 1.83e-04

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 43.79  E-value: 1.83e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 325 PAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVhppapgvhPPPSAGVHPQAPGVHPPA 404
Cdd:PTZ00436 222 PAKAAAAPAKAAAPPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAAAPPAKAA--------APPAKAAAPPAKAAAPPA 293

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 158749553 405 PAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPGVHPS 453
Cdd:PTZ00436 294 KAAAAPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAATPPAKAAAPPA 342
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 332-458 1.92e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.21  E-value: 1.92e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 332 PTPGVHPPAPGVHPPAPGVhPPAPGVHPPTPGVHPPAPgvhPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQA 411
Cdd:PRK07764 386 GVAGGAGAPAAAAPSAAAA-APAAAPAPAAAAPAAAAA---PAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAA 461

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 158749553 412 PGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPGVHPSNPGVH 458
Cdd:PRK07764 462 PSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADD 508
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 324-441 2.02e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.82  E-value: 2.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 324 PPAPGVHPPTPGVHPPAPgvhPPAPGVHPPAPGVHPPTPgvhPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPP 403
Cdd:PRK07764 405 APAAAPAPAAAAPAAAAA---PAPAAAPQPAPAPAPAPA---PPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTA 478

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 158749553 404 APAVHPQApgvhPPAPGIHPQAPGVHPQPPPGVHPAAP 441
Cdd:PRK07764 479 APAPAPPA----APAPAAAPAAPAAPAAPAGADDAATL 512
PHA03247 PHA03247
large tegument protein UL36; Provisional
 299-454 2.52e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.77  E-value: 2.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  299 SGVHPPAPGVHPPAPVVHPPTSGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPGV 378
Cdd:PHA03247 2812 LAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAV 2891

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 158749553  379 HPPAPGVHPPPSAgvhPQAPGVHPPAPAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPGVHPSN 454
Cdd:PHA03247 2892 SRSTESFALPPDQ---PERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWL 2964
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 303-409 4.41e-04

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 42.63  E-value: 4.41e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 303 PPAPGVHPPAPVVHPPTSGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPA 382
Cdd:PTZ00436 242 APAKAAAAPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAAPAKAAAAPAKAAAAPAKAAAPPA 321

                         90       100
                 ....*....|....*....|....*..
gi 158749553 383 PGVHPPPSAGVHPQAPGVHPPAPAVHP 409
Cdd:PTZ00436 322 KAAAPPAKAATPPAKAAAPPAKAAAAP 348
PHA03247 PHA03247
large tegument protein UL36; Provisional
 325-455 4.50e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 4.50e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  325 PAPGVHPPTPGVHPPAPGVhpPAPGVHPPAP---GVHP-------------------PTPGVHPPAPgvhPPAPgvhppa 382
Cdd:PHA03247 2496 PDPGGGGPPDPDAPPAPSR--LAPAILPDEPvgePVHPrmltwirgleelasddagdPPPPLPPAAP---PAAP------ 2564

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 158749553  383 pgvhpppSAGVHPQAPGVHPPAPAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGvhPAAPGvhPQPPGVHPSNP 455
Cdd:PHA03247 2565 -------DRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRG--PAPPS--PLPPDTHAPDP 2626
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
321-453 5.58e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 42.53  E-value: 5.58e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 321 GVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGv 400
Cdd:PRK07003 371 GVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPV- 449

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 158749553 401 hpPAPAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPGVHPS 453
Cdd:PRK07003 450 --PAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPS 500
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
303-445 1.07e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.79  E-value: 1.07e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 303 PPAPGVHPPAPVVHPPTSGVHPPAPGVHPPTPGVHPPAPGVHPP---APGVHPPAPGVHPPT--------PGVHPPAPGV 371
Cdd:PRK12323 375 ATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAvaaAPARRSPAPEALAAArqasargpGGAPAPAPAP 454

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 158749553 372 HP-PAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHP 445
Cdd:PRK12323 455 AAaPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDP 529
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 303-413 1.12e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.51  E-value: 1.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 303 PPAPGVHPPAPVVHPPTSGVHPPAPGVHPPtPGVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPA 382
Cdd:PRK07764 396 AAAPSAAAAAPAAAPAPAAAAPAAAAAPAP-AAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAP 474

                         90       100       110
                 ....*....|....*....|....*....|.
gi 158749553 383 PGVHPPPSAGVHPQAPGVHPPAPAVHPQAPG 413
Cdd:PRK07764 475 EPTAAPAPAPPAAPAPAAAPAAPAAPAAPAG 505
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 337-456 1.69e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 1.69e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 337 HPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVHPPAPgvhppapgvhpppSAGVHPQAPGVHP-PAPAVHPQAPGVH 415
Cdd:PRK07764 385 LGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPA-------------PAAAPQPAPAPAPaPAPPSPAGNAPAG 451

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 158749553 416 PPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPPGVHPSNPG 456
Cdd:PRK07764 452 GAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAA 492
PHA02030 PHA02030
hypothetical protein
 347-428 1.75e-03

hypothetical protein


Pssm-ID: 222843 [Multi-domain]  Cd Length: 336  Bit Score: 40.35  E-value: 1.75e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 347 APGVHPPAPGVHPPTPGVHPpAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQAPGVhppaPGIhPQAP 426
Cdd:PHA02030 261 AAGSNLPAVPNVAADAGSAA-APAVPAAAAAVAQAAPSVPQVPNVAVLPDVPQVAPVAAPAAPEVPAV----PVV-PAAP 334


                 ..
gi 158749553 427 GV 428
Cdd:PHA02030 335 QV 336
GGN pfam15685
Gametogenetin; GGN is a family of proteins largely found in mammals. It reacts with POG in the ...
 349-447 2.74e-03

Gametogenetin; GGN is a family of proteins largely found in mammals. It reacts with POG in the maturation of sperm and is expressed virtually only in the testis. It is found to be associated with the intracellular membrane, binds with GGNBP1 and may be involved in vesicular trafficking.


Pssm-ID: 434857 [Multi-domain]  Cd Length: 668  Bit Score: 40.14  E-value: 2.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  349 GVHPPAPGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQAPGVHPPApgihPQAPGV 428
Cdd:pfam15685 391 GSPPPPPGKAHPIPGPRRPAPALLAPPMFIFPAPTNGEPVRPGPPAPQALLPRPPPPTPPATPPPVPPPI----PQLPAL 466

                          90
                  ....*....|....*....
gi 158749553  429 HPQPPPGVHPAAPGVHPQP 447
Cdd:pfam15685 467 QPMPLAAARPPTPRPCPGH 485
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 322-447 3.24e-03

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 40.14  E-value: 3.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 322 VHPPAPGVHPPTPGVHPPAPGVHP-PAPGVHPPAPGVHP----PTPGVHP----PAPGVHP----PAPGVHPPAPGVHPP 388
Cdd:NF033839 307 KKEVKPEPETPKPEVKPQLEKPKPeVKPQPEKPKPEVKPqletPKPEVKPqpekPKPEVKPqpekPKPEVKPQPETPKPE 386

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 158749553 389 PSAGVHPQAPGVHP----PAPAVHPQ--------APGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQP 447
Cdd:NF033839 387 VKPQPEKPKPEVKPqpekPKPEVKPQpekpkpevKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQP 457
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 298-441 3.26e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.15  E-value: 3.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  298 TSGVHPPAPGVHPPAPVVHPPTSGVHPPAPGVHPPTPGVHPPApgvhPPAPGVHPPAPGvHPPTPGVHPPAPGVHPPAPG 377
Cdd:PHA03307   73 PGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPD----PPPPTPPPASPP-PSPAPDLSEMLRPVGSPGPP 147

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 158749553  378 VHPPAPGVHPPPSAgvhPQAPGVHPPAPAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGVHPAAP 441
Cdd:PHA03307  148 PAASPPAAGASPAA---VASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPR 208
PHA03247 PHA03247
large tegument protein UL36; Provisional
 215-452 3.68e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.31  E-value: 3.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  215 EKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPDALPPPPPGGLPLPPMPPTGPAPSGPPGPPQMPPPAPGVHPPAPVV 294
Cdd:PHA03247 2754 PARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTS 2833

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  295 HPPTSGVHPPAPGVHPPAPVVHPPTSG----VHPPAPGVHPPTPGVHPPAPGVHPPAPGvHPPAPGVHPPTPGVHPPAPg 370
Cdd:PHA03247 2834 AQPTAPPPPPGPPPPSLPLGGSVAPGGdvrrRPPSRSPAAKPAAPARPPVRRLARPAVS-RSTESFALPPDQPERPPQP- 2911

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  371 vHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQA---PGVHPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQP 447
Cdd:PHA03247 2912 -QAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGagePSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPA 2990


                  ....*
gi 158749553  448 PGVHP 452
Cdd:PHA03247 2991 SSTPP 2995
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 352-454 5.32e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 39.41  E-value: 5.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 352 PPAPGVHPPTPgvhpPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQAPGVHPPAPGIHPQAPGVHPQ 431
Cdd:PRK14950 363 VPAPQPAKPTA----AAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESAPKLTRAAIPV 438

                         90       100
                 ....*....|....*....|...
gi 158749553 432 PppgVHPAAPGVHPQPPGVHPSN 454
Cdd:PRK14950 439 D---EKPKYTPPAPPKEEEKALI 458
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 322-455 5.65e-03

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 38.98  E-value: 5.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 322 VHPPAPGVHPPTP-GVHPPAPGVHPPAPGVHPPAPGVHPPTPGVHPPAPGVH-----PPAPGVHPPAPGVHPPPSAGVHP 395
Cdd:NF040712 202 VPRLAREPADARPeEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEqpedePVGPGAAPAAEPDEATRDAGEPP 281

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553 396 qAPGVHPPAPAVHPQAPGVHPPAPgihPQAPGVHPQPPPGVHPAAPgvhPQPPGVHPSNP 455
Cdd:NF040712 282 -APGAAETPEAAEPPAPAPAAPAA---PAAPEAEEPARPEPPPAPK---PKRRRRRASVP 334
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 319-464 6.57e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 39.30  E-value: 6.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158749553  319 TSGVHPPAPGVHPPTPGVHPPAPGVHPPAPGVH-PPAPGVHPPTPgVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQA 397
Cdd:PRK10263  327 TTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAwQPVPGPQTGEP-VIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQ 405

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 158749553  398 PGVHPPAPAVHPQAPGVHPPAPGIHPQAPGVHPQPPPGV---HPAAPGVHPQPPGVH-PSNPGVHPAPMPP 464
Cdd:PRK10263  406 PYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGnawQAEEQQSTFAPQSTYqTEQTYQQPAAQEP 476
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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