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Conserved domains on  [gi|163954951|ref|NP_035704|]
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U3 small nucleolar RNA-associated protein 4 homolog [Mus musculus]

Protein Classification

WD40 repeat domain-containing protein( domain architecture ID 11455410)

WD40 repeat domain-containing protein similar to proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly

CATH:  2.130.10.10
PubMed:  10322433|8090199
SCOP:  4002744

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
7-306 1.82e-35

WD40 repeat [General function prediction only];


:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 138.89  E-value: 1.82e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951   7 HRVRFFNYVPSGIRCVAYNNQSNRLAVSRTDGTVEIYNLsANYFQEKFFPGHESRGTeALCW-AGGQRLFSAGLNGEILE 85
Cdd:COG2319  111 LLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDL-ATGKLLRTLTGHSGAVT-SVAFsPDGKLLASGSDDGTVRL 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951  86 YDLQALNIKYTLDAFGGPIWSMTASPSGSQLLVGCEDGSVKLFEVTPEKIQfaRNFDRQKSRILSLCWHPAGTHVAAGSL 165
Cdd:COG2319  189 WDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLL--RTLTGHSGSVRSVAFSPDGRLLASGSA 266

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 166 D-YISVFDVKSGSIIRKMvldRQHLGVtksrciVWGVAFLSDG-TVISVDSVGKVQLWDSATGTLVKSHLVANADVQSIA 243
Cdd:COG2319  267 DgTVRLWDLATGELLRTL---TGHSGG------VNSVAFSPDGkLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVA 337

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 163954951 244 VADQEDSFVVGTAEGTVfhfQLVSMTSNSsekqwvRTKPFQHHTHDVRAVAHSP--TALISGGTD 306
Cdd:COG2319  338 FSPDGKTLASGSDDGTV---RLWDLATGE------LLRTLTGHTGAVTSVAFSPdgRTLASGSAD 393
WD40 COG2319
WD40 repeat [General function prediction only];
343-550 2.63e-13

WD40 repeat [General function prediction only];


:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 72.25  E-value: 2.63e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 343 RRQLLLFQFAHHLELWRLGSTSATGKNGDTLPLSKNADHLLHLKTKGPENIICSCV-SPCGSWIAysTASRFFLYRLKYE 421
Cdd:COG2319   30 LLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAfSPDGRLLA--SASADGTVRLWDL 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 422 RDNISLQRVSKLPSFLRSalhILFSEDSTKLLVASNQGSLHIVHLSEGsfKHLHTFQPQSGTVEAmclLAVSPDGNWLAA 501
Cdd:COG2319  108 ATGLLLRTLTGHTGAVRS---VAFSPDGKTLASGSADGTVRLWDLATG--KLLRTLTGHSGAVTS---VAFSPDGKLLAS 179

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 163954951 502 SGTSAGVHVYDLHHLKLHCTVPAYNFPVTALAIAPNTNNLVIAHSDQQV 550
Cdd:COG2319  180 GSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTV 228
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
7-306 1.82e-35

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 138.89  E-value: 1.82e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951   7 HRVRFFNYVPSGIRCVAYNNQSNRLAVSRTDGTVEIYNLsANYFQEKFFPGHESRGTeALCW-AGGQRLFSAGLNGEILE 85
Cdd:COG2319  111 LLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDL-ATGKLLRTLTGHSGAVT-SVAFsPDGKLLASGSDDGTVRL 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951  86 YDLQALNIKYTLDAFGGPIWSMTASPSGSQLLVGCEDGSVKLFEVTPEKIQfaRNFDRQKSRILSLCWHPAGTHVAAGSL 165
Cdd:COG2319  189 WDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLL--RTLTGHSGSVRSVAFSPDGRLLASGSA 266

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 166 D-YISVFDVKSGSIIRKMvldRQHLGVtksrciVWGVAFLSDG-TVISVDSVGKVQLWDSATGTLVKSHLVANADVQSIA 243
Cdd:COG2319  267 DgTVRLWDLATGELLRTL---TGHSGG------VNSVAFSPDGkLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVA 337

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 163954951 244 VADQEDSFVVGTAEGTVfhfQLVSMTSNSsekqwvRTKPFQHHTHDVRAVAHSP--TALISGGTD 306
Cdd:COG2319  338 FSPDGKTLASGSDDGTV---RLWDLATGE------LLRTLTGHTGAVTSVAFSPdgRTLASGSAD 393
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 16-306 4.09e-33

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 128.99  E-value: 4.09e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951  16 PSGIRCVAYNNQSNRLAVSRTDGTVEIYNLSANyFQEKFFPGHESRGTEALCWAGGQRLFSAGLNGEILEYDLQALNIKY 95
Cdd:cd00200    9 TGGVTCVAFSPDGKLLATGSGDGTIKVWDLETG-ELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVR 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951  96 TLDAFGGPIWSMTASPSGsQLLVGC-EDGSVKLFEVTPEKIQFArnFDRQKSRILSLCWHPAGTHVAAGSLD-YISVFDV 173
Cdd:cd00200   88 TLTGHTSYVSSVAFSPDG-RILSSSsRDKTIKVWDVETGKCLTT--LRGHTDWVNSVAFSPDGTFVASSSQDgTIKLWDL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 174 KSGSIIrkmvldRQHLGVTKSrciVWGVAFLSDG-TVISVDSVGKVQLWDSATGTLVKSHLVANADVQSIAVADQEDSFV 252
Cdd:cd00200  165 RTGKCV------ATLTGHTGE---VNSVAFSPDGeKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLA 235

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 163954951 253 VGTAEGTVFHFQLVSmtsnssekqWVRTKPFQHHTHDVRAVAHSPTA--LISGGTD 306
Cdd:cd00200  236 SGSEDGTIRVWDLRT---------GECVQTLSGHTNSVTSLAWSPDGkrLASGSAD 282
WD40 COG2319
WD40 repeat [General function prediction only];
343-550 2.63e-13

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 72.25  E-value: 2.63e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 343 RRQLLLFQFAHHLELWRLGSTSATGKNGDTLPLSKNADHLLHLKTKGPENIICSCV-SPCGSWIAysTASRFFLYRLKYE 421
Cdd:COG2319   30 LLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAfSPDGRLLA--SASADGTVRLWDL 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 422 RDNISLQRVSKLPSFLRSalhILFSEDSTKLLVASNQGSLHIVHLSEGsfKHLHTFQPQSGTVEAmclLAVSPDGNWLAA 501
Cdd:COG2319  108 ATGLLLRTLTGHTGAVRS---VAFSPDGKTLASGSADGTVRLWDLATG--KLLRTLTGHSGAVTS---VAFSPDGKLLAS 179

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 163954951 502 SGTSAGVHVYDLHHLKLHCTVPAYNFPVTALAIAPNTNNLVIAHSDQQV 550
Cdd:COG2319  180 GSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTV 228
ANAPC4_WD40 pfam12894
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ...
 107-202 3.62e-05

Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,


Pssm-ID: 403945 [Multi-domain]  Cd Length: 91  Bit Score: 42.65  E-value: 3.62e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951  107 MTASPSGSQLLVGCEDGSVKLFEVTPEKIqFARNFDRQKSRILSLCWHPAGTHVAAGSLD-YISVFDVKSGSIIRKmvLD 185
Cdd:pfam12894   1 MSWCPTMDLIALATEDGELLLHRLNWQRV-WTLSPDKEDLEVTSLAWRPDGKLLAVGYSDgTVRLLDAENGKIVHH--FS 77

                          90
                  ....*....|....*..
gi 163954951  186 RQHLGVTksrCIVWGVA 202
Cdd:pfam12894  78 AGSDLIT---CLGWGEN 91
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 445-590 1.56e-04

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 44.25  E-value: 1.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 445 FSEDSTKLLVASNQGSLHIVHLSEGSFkhLHTFQPQSGTVEAmclLAVSPDGNWLAASGTSAGVHVYDLHHLKLHCTVPA 524
Cdd:cd00200   17 FSPDGKLLATGSGDGTIKVWDLETGEL--LRTLKGHTGPVRD---VAASADGTYLASGSSDKTIRLWDLETGECVRTLTG 91

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 163954951 525 YNFPVTALAIAPNTNNLVIAHSDQQVFEFSIPEKQYTewsRSLQkqgFHQLWlqrdtpITHISFHP 590
Cdd:cd00200   92 HTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCL---TTLR---GHTDW------VNSVAFSP 145
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 92-129 9.99e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 37.29  E-value: 9.99e-04
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 163954951    92 NIKYTLDAFGGPIWSMTASPSGSQLLVGCEDGSVKLFE 129
Cdd:smart00320   3 ELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
7-306 1.82e-35

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 138.89  E-value: 1.82e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951   7 HRVRFFNYVPSGIRCVAYNNQSNRLAVSRTDGTVEIYNLsANYFQEKFFPGHESRGTeALCW-AGGQRLFSAGLNGEILE 85
Cdd:COG2319  111 LLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDL-ATGKLLRTLTGHSGAVT-SVAFsPDGKLLASGSDDGTVRL 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951  86 YDLQALNIKYTLDAFGGPIWSMTASPSGSQLLVGCEDGSVKLFEVTPEKIQfaRNFDRQKSRILSLCWHPAGTHVAAGSL 165
Cdd:COG2319  189 WDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLL--RTLTGHSGSVRSVAFSPDGRLLASGSA 266

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 166 D-YISVFDVKSGSIIRKMvldRQHLGVtksrciVWGVAFLSDG-TVISVDSVGKVQLWDSATGTLVKSHLVANADVQSIA 243
Cdd:COG2319  267 DgTVRLWDLATGELLRTL---TGHSGG------VNSVAFSPDGkLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVA 337

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 163954951 244 VADQEDSFVVGTAEGTVfhfQLVSMTSNSsekqwvRTKPFQHHTHDVRAVAHSP--TALISGGTD 306
Cdd:COG2319  338 FSPDGKTLASGSDDGTV---RLWDLATGE------LLRTLTGHTGAVTSVAFSPdgRTLASGSAD 393
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 16-306 4.09e-33

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 128.99  E-value: 4.09e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951  16 PSGIRCVAYNNQSNRLAVSRTDGTVEIYNLSANyFQEKFFPGHESRGTEALCWAGGQRLFSAGLNGEILEYDLQALNIKY 95
Cdd:cd00200    9 TGGVTCVAFSPDGKLLATGSGDGTIKVWDLETG-ELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVR 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951  96 TLDAFGGPIWSMTASPSGsQLLVGC-EDGSVKLFEVTPEKIQFArnFDRQKSRILSLCWHPAGTHVAAGSLD-YISVFDV 173
Cdd:cd00200   88 TLTGHTSYVSSVAFSPDG-RILSSSsRDKTIKVWDVETGKCLTT--LRGHTDWVNSVAFSPDGTFVASSSQDgTIKLWDL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 174 KSGSIIrkmvldRQHLGVTKSrciVWGVAFLSDG-TVISVDSVGKVQLWDSATGTLVKSHLVANADVQSIAVADQEDSFV 252
Cdd:cd00200  165 RTGKCV------ATLTGHTGE---VNSVAFSPDGeKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLA 235

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 163954951 253 VGTAEGTVFHFQLVSmtsnssekqWVRTKPFQHHTHDVRAVAHSPTA--LISGGTD 306
Cdd:cd00200  236 SGSEDGTIRVWDLRT---------GECVQTLSGHTNSVTSLAWSPDGkrLASGSAD 282
WD40 COG2319
WD40 repeat [General function prediction only];
17-260 5.39e-32

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 128.49  E-value: 5.39e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951  17 SGIRCVAYNNQSNRLAVSRTDGTVEIYNLSANYfQEKFFPGHESRGTeALCWA-GGQRLFSAGLNGEILEYDLQALNIKY 95
Cdd:COG2319  163 GAVTSVAFSPDGKLLASGSDDGTVRLWDLATGK-LLRTLTGHTGAVR-SVAFSpDGKLLASGSADGTVRLWDLATGKLLR 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951  96 TLDAFGGPIWSMTASPSGSQLLVGCEDGSVKLFEVTPEKIQfaRNFDRQKSRILSLCWHPAGTHVAAGSLDY-ISVFDVK 174
Cdd:COG2319  241 TLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELL--RTLTGHSGGVNSVAFSPDGKLLASGSDDGtVRLWDLA 318

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 175 SGSIIrkmvldRQHLGVTKSrciVWGVAFLSDG-TVISVDSVGKVQLWDSATGTLVKSHLVANADVQSIAVADQEDSFVV 253
Cdd:COG2319  319 TGKLL------RTLTGHTGA---VRSVAFSPDGkTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLAS 389


                 ....*..
gi 163954951 254 GTAEGTV 260
Cdd:COG2319  390 GSADGTV 396
WD40 COG2319
WD40 repeat [General function prediction only];
55-550 7.02e-30

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 122.33  E-value: 7.02e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951  55 FPGHESRGTEALCWAGGQRLFSAGLNGEILEYDLQALNIKYTLDAFGGPIWSMTASPSGSQLLVGCEDGSVKLFEVTPEK 134
Cdd:COG2319   32 LLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLATGL 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 135 IqfARNFDRQKSRILSLCWHPAGTHVAAGSLDY-ISVFDVKSGSIIRkmVLDRQHLGVtksrcivWGVAFLSDG-TVISV 212
Cdd:COG2319  112 L--LRTLTGHTGAVRSVAFSPDGKTLASGSADGtVRLWDLATGKLLR--TLTGHSGAV-------TSVAFSPDGkLLASG 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 213 DSVGKVQLWDSATGTLVKSHLVANADVQSIAVADQEDSFVVGTAEGTVfhfQLVSMTSNssekQWVRTkpFQHHTHDVRA 292
Cdd:COG2319  181 SDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTV---RLWDLATG----KLLRT--LTGHSGSVRS 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 293 VAHSP--TALISGGTDthlvirplmervevknydaalrkitfphrrliscskrrqlllfqfaHHLELWRLgstsATGKNG 370
Cdd:COG2319  252 VAFSPdgRLLASGSAD----------------------------------------------GTVRLWDL----ATGELL 281

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 371 DTLplsknadhllhlktKGPENIICSCVspcgswiaystasrfflyrlkyerdnislqrvsklpsflrsalhilFSEDST 450
Cdd:COG2319  282 RTL--------------TGHSGGVNSVA----------------------------------------------FSPDGK 301

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 451 KLLVASNQGSLHIVHLSEGsfKHLHTFQPQSGTVEAmclLAVSPDGNWLAASGTSAGVHVYDLHHLKLHCTVPAYNFPVT 530
Cdd:COG2319  302 LLASGSDDGTVRLWDLATG--KLLRTLTGHTGAVRS---VAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVT 376

                        490       500
                 ....*....|....*....|
gi 163954951 531 ALAIAPNTNNLVIAHSDQQV 550
Cdd:COG2319  377 SVAFSPDGRTLASGSADGTV 396
WD40 COG2319
WD40 repeat [General function prediction only];
16-513 2.62e-28

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 117.70  E-value: 2.62e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951  16 PSGIRCVAYNNQSNRLAVSRTDGTVEIYNLSANYfQEKFFPGHESRGTEALCWAGGQRLFSAGLNGEILEYDLQALNIKY 95
Cdd:COG2319   36 AAAVASLAASPDGARLAAGAGDLTLLLLDAAAGA-LLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLR 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951  96 TLDAFGGPIWSMTASPSGSQLLVGCEDGSVKLFEVTPEKiqFARNFDRQKSRILSLCWHPAGTHVAAGSLDY-ISVFDVK 174
Cdd:COG2319  115 TLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGK--LLRTLTGHSGAVTSVAFSPDGKLLASGSDDGtVRLWDLA 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 175 SGSIIRKMvldRQHLGVtksrciVWGVAFLSDG-TVISVDSVGKVQLWDSATGTLVKSHLVANADVQSIAVADQEDSFVV 253
Cdd:COG2319  193 TGKLLRTL---TGHTGA------VRSVAFSPDGkLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLAS 263

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 254 GTAEGTVFHFQLvsmtsnsSEKQWVRTkpFQHHTHDVRAVAHSP--TALISGGTDthlvirplmervevknydaalrkit 331
Cdd:COG2319  264 GSADGTVRLWDL-------ATGELLRT--LTGHSGGVNSVAFSPdgKLLASGSDD------------------------- 309

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 332 fphrrliscskrrqlllfqfaHHLELWRLgstsATGKNGDTLplsknadhllhlktKGPENIICSCVspcgswiaystas 411
Cdd:COG2319  310 ---------------------GTVRLWDL----ATGKLLRTL--------------TGHTGAVRSVA------------- 337

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 412 rfflyrlkyerdnislqrvsklpsflrsalhilFSEDSTKLLVASNQGSLHIVHLSEGsfKHLHTFQPQSGTVEAmclLA 491
Cdd:COG2319  338 ---------------------------------FSPDGKTLASGSDDGTVRLWDLATG--ELLRTLTGHTGAVTS---VA 379

                        490       500
                 ....*....|....*....|..
gi 163954951 492 VSPDGNWLAASGTSAGVHVYDL 513
Cdd:COG2319  380 FSPDGRTLASGSADGTVRLWDL 401
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 96-411 4.07e-16

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 79.30  E-value: 4.07e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951  96 TLDAFGGPIWSMTASPSGSQLLVGCEDGSVKLFEVTPEKIQFarnfdRQKSRILSLCW---HPAGTHVAAGSLDY-ISVF 171
Cdd:cd00200    4 TLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLR-----TLKGHTGPVRDvaaSADGTYLASGSSDKtIRLW 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 172 DVKSGSIIRKMVldrqhlGVTKSrciVWGVAFLSDGTVISVDSV-GKVQLWDSATGTLVKSHLVANADVQSIAVaDQEDS 250
Cdd:cd00200   79 DLETGECVRTLT------GHTSY---VSSVAFSPDGRILSSSSRdKTIKVWDVETGKCLTTLRGHTDWVNSVAF-SPDGT 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 251 FVV-GTAEGTVFhfqLVSMTSNSSEKQwvrtkpFQHHTHDVRAVAHSPTA--LISGGTDTHLVIRPLMERVEVKNYDAAL 327
Cdd:cd00200  149 FVAsSSQDGTIK---LWDLRTGKCVAT------LTGHTGEVNSVAFSPDGekLLSSSSDGTIKLWDLSTGKCLGTLRGHE 219

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 328 RKITF----PHRRLI-SCSKRRqlllfqfahHLELWRLgstsATGKNGDTLPLSKNAdhllhlktkgpenIICSCVSPCG 402
Cdd:cd00200  220 NGVNSvafsPDGYLLaSGSEDG---------TIRVWDL----RTGECVQTLSGHTNS-------------VTSLAWSPDG 273


                 ....*....
gi 163954951 403 SWIAysTAS 411
Cdd:cd00200  274 KRLA--SGS 280
WD40 COG2319
WD40 repeat [General function prediction only];
343-550 2.63e-13

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 72.25  E-value: 2.63e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 343 RRQLLLFQFAHHLELWRLGSTSATGKNGDTLPLSKNADHLLHLKTKGPENIICSCV-SPCGSWIAysTASRFFLYRLKYE 421
Cdd:COG2319   30 LLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAfSPDGRLLA--SASADGTVRLWDL 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 422 RDNISLQRVSKLPSFLRSalhILFSEDSTKLLVASNQGSLHIVHLSEGsfKHLHTFQPQSGTVEAmclLAVSPDGNWLAA 501
Cdd:COG2319  108 ATGLLLRTLTGHTGAVRS---VAFSPDGKTLASGSADGTVRLWDLATG--KLLRTLTGHSGAVTS---VAFSPDGKLLAS 179

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 163954951 502 SGTSAGVHVYDLHHLKLHCTVPAYNFPVTALAIAPNTNNLVIAHSDQQV 550
Cdd:COG2319  180 GSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTV 228
WD40 COG2319
WD40 repeat [General function prediction only];
8-131 2.59e-12

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 69.17  E-value: 2.59e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951   8 RVRFFNYVPSGIRCVAYNNQSNRLAVSRTDGTVEIYNLsANYFQEKFFPGHESRGTeALCW-AGGQRLFSAGLNGEILEY 86
Cdd:COG2319  280 LLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDL-ATGKLLRTLTGHTGAVR-SVAFsPDGKTLASGSDDGTVRLW 357

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 163954951  87 DLQALNIKYTLDAFGGPIWSMTASPSGSQLLVGCEDGSVKLFEVT 131
Cdd:COG2319  358 DLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLA 402
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 17-129 1.17e-10

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 63.12  E-value: 1.17e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951  17 SGIRCVAYNNQSNRLAVSRTDGTVEIYNLSANyFQEKFFPGHESRGTeALCWAGGQRLF-SAGLNGEILEYDLQALNIKY 95
Cdd:cd00200  178 GEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTG-KCLGTLRGHENGVN-SVAFSPDGYLLaSGSEDGTIRVWDLRTGECVQ 255

                         90       100       110
                 ....*....|....*....|....*....|....
gi 163954951  96 TLDAFGGPIWSMTASPSGSQLLVGCEDGSVKLFE 129
Cdd:cd00200  256 TLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
ANAPC4_WD40 pfam12894
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ...
 107-202 3.62e-05

Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,


Pssm-ID: 403945 [Multi-domain]  Cd Length: 91  Bit Score: 42.65  E-value: 3.62e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951  107 MTASPSGSQLLVGCEDGSVKLFEVTPEKIqFARNFDRQKSRILSLCWHPAGTHVAAGSLD-YISVFDVKSGSIIRKmvLD 185
Cdd:pfam12894   1 MSWCPTMDLIALATEDGELLLHRLNWQRV-WTLSPDKEDLEVTSLAWRPDGKLLAVGYSDgTVRLLDAENGKIVHH--FS 77

                          90
                  ....*....|....*..
gi 163954951  186 RQHLGVTksrCIVWGVA 202
Cdd:pfam12894  78 AGSDLIT---CLGWGEN 91
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 445-590 1.56e-04

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 44.25  E-value: 1.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 445 FSEDSTKLLVASNQGSLHIVHLSEGSFkhLHTFQPQSGTVEAmclLAVSPDGNWLAASGTSAGVHVYDLHHLKLHCTVPA 524
Cdd:cd00200   17 FSPDGKLLATGSGDGTIKVWDLETGEL--LRTLKGHTGPVRD---VAASADGTYLASGSSDKTIRLWDLETGECVRTLTG 91

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 163954951 525 YNFPVTALAIAPNTNNLVIAHSDQQVFEFSIPEKQYTewsRSLQkqgFHQLWlqrdtpITHISFHP 590
Cdd:cd00200   92 HTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCL---TTLR---GHTDW------VNSVAFSP 145
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
395-544 6.60e-04

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 41.99  E-value: 6.60e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 395 CSCVSPCGSWIAYSTASRFFLYRLKYERDNISLQRVSKLPSFLRSALHILFSEDSTKLLVASNQGSLHIVHLSEGSFKHL 474
Cdd:COG3391   24 AVAALGLGGGGPLLAAASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRLYVANSGSGRVSVIDLATGKVV 103

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 163954951 475 HTFQPQSGTVEamclLAVSPDGNWL-AASGTSAGVHVYDLHHLKLHCTVPAYNFPvTALAIAPNTNNLVIA 544
Cdd:COG3391  104 ATIPVGGGPRG----LAVDPDGGRLyVADSGNGRVSVIDTATGKVVATIPVGAGP-HGIAVDPDGKRLYVA 169
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 92-129 9.99e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 37.29  E-value: 9.99e-04
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 163954951    92 NIKYTLDAFGGPIWSMTASPSGSQLLVGCEDGSVKLFE 129
Cdd:smart00320   3 ELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
442-547 2.68e-03

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 40.06  E-value: 2.68e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 442 HILFSEDSTKLLVA-SNQGSLHIVHLSEGSFkhLHTFQPQSGTVEamclLAVSPDGNWLAASGTSAG-----VHVYDLHH 515
Cdd:COG3391  114 GLAVDPDGGRLYVAdSGNGRVSVIDTATGKV--VATIPVGAGPHG----IAVDPDGKRLYVANSGSNtvsviVSVIDTAT 187

                         90       100       110
                 ....*....|....*....|....*....|..
gi 163954951 516 LKLHCTVPAYNFPVtALAIAPNTNNLVIAHSD 547
Cdd:COG3391  188 GKVVATIPVGGGPV-GVAVSPDGRRLYVANRG 218
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 387-513 6.33e-03

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 38.11  E-value: 6.33e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 387 TKGPENIICSCVSPCGSWIAYST--ASRFFLYRlkYERDNISLQRVSKLPSFLRSALhilFSEDSTKLLVASNQGS---L 461
Cdd:COG0823   27 TNSPGIDTSPAWSPDGRRIAFTSdrGGGPQIYV--VDADGGEPRRLTFGGGYNASPS---WSPDGKRLAFVSRSDGrfdI 101

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 163954951 462 HIVHLSEGSFKHLhTFQPQSGtveamcllAVSPDGNWLAASGTSAG---VHVYDL 513
Cdd:COG0823  102 YVLDLDGGAPRRL-TDGPGSP--------SWSPDGRRIVFSSDRGGrpdLYVVDL 147
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 490-594 8.43e-03

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 38.86  E-value: 8.43e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163954951 490 LAVSPDGNWLAASGTSAGVHVYDLHHLKLHCTVPAYNFPVTALAIAPNTNNLVIAHSDQQVFEFsipekqytewsrSLQK 569
Cdd:cd00200   15 VAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLW------------DLET 82

                         90       100
                 ....*....|....*....|....*
gi 163954951 570 QGFHQLWLQRDTPITHISFHPKRPM 594
Cdd:cd00200   83 GECVRTLTGHTSYVSSVAFSPDGRI 107
WD40 pfam00400
WD domain, G-beta repeat;
95-129 9.96e-03

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 34.24  E-value: 9.96e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 163954951   95 YTLDAFGGPIWSMTASPSGSQLLVGCEDGSVKLFE 129
Cdd:pfam00400   5 KTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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