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Conserved domains on  [gi|7106409|ref|NP_035523|]
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excitatory amino acid transporter 2 isoform 3 [Mus musculus]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10003465)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
40-489 7.18e-122

Na+/H+-dicarboxylate symporter [Energy production and conversion];


:

Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 364.82  E-value: 7.18e-122
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   40 KNLLLSLTVFGVILGAVCGGLLrlaspiHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAM 118
Cdd:COG1301   2 KLSLTLQILIALVLGILLGLLL------PELVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409  119 VYYMSTTIIAAVLGVILVLAIHPGNPkLKKQLGPGKKNDEVSSLDaFLDLIRNLFPENLVQAcfqqiqtvtkkvlvapps 198
Cdd:COG1301  76 LYFLVTTTIALVIGLVVANLFQPGAG-LNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA------------------ 135

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409  199 eeanttkavismlnetmneapeetkivikkgleFKDGmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVI 278
Cdd:COG1301 136 ---------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVG 181

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409  279 MIMWYSPLGIACLIcGKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTA 358
Cdd:COG1301 182 WVMKLAPIGVFALI-AATVAKYGLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTS 259

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409  359 SSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASI 438
Cdd:COG1301 260 SSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGV 339

                       410       420       430       440       450
                ....*....|....*....|....*....|....*....|....*....|.
gi 7106409  439 PSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIV 489
Cdd:COG1301 340 PGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVV 390
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
40-489 7.18e-122

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 364.82  E-value: 7.18e-122
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   40 KNLLLSLTVFGVILGAVCGGLLrlaspiHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAM 118
Cdd:COG1301   2 KLSLTLQILIALVLGILLGLLL------PELVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409  119 VYYMSTTIIAAVLGVILVLAIHPGNPkLKKQLGPGKKNDEVSSLDaFLDLIRNLFPENLVQAcfqqiqtvtkkvlvapps 198
Cdd:COG1301  76 LYFLVTTTIALVIGLVVANLFQPGAG-LNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA------------------ 135

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409  199 eeanttkavismlnetmneapeetkivikkgleFKDGmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVI 278
Cdd:COG1301 136 ---------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVG 181

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409  279 MIMWYSPLGIACLIcGKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTA 358
Cdd:COG1301 182 WVMKLAPIGVFALI-AATVAKYGLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTS 259

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409  359 SSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASI 438
Cdd:COG1301 260 SSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGV 339

                       410       420       430       440       450
                ....*....|....*....|....*....|....*....|....*....|.
gi 7106409  439 PSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIV 489
Cdd:COG1301 340 PGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVV 390
SDF pfam00375
Sodium:dicarboxylate symporter family;
43-492 1.14e-121

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 363.38  E-value: 1.14e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409     43 LLSLTVFGVILGAVCGGLLrlaspihPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAMVYY 121
Cdd:pfam00375   1 LLLQILIALVLGILIGLFF-------PELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYF 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409    122 MSTTIIAAVLGVILVLAIHPGNPKLKKQLGPgkKNDEVSSLDAFLDLIRNLFPENLVQACFQQiqtvtkkvlvappseea 201
Cdd:pfam00375  74 LVTTAIAALIGLLVANVFQPGSGLALIAASL--KEAKAAEAPSLLDFILNIIPSNIFEALAEG----------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409    202 nttkavismlnetmneapeetkivikkglefkdgmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIM 281
Cdd:pfam00375 135 -----------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVM 179

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409    282 WYSPLGIACLICgKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSA 361
Cdd:pfam00375 180 KLAPIGVFALIA-NTVGTYGLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSA 257

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409    362 GTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSA 441
Cdd:pfam00375 258 ATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGG 337

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 7106409    442 GLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL 492
Cdd:pfam00375 338 GLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 40-499 4.58e-40

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 150.82  E-value: 4.58e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409    40 KNLLLSLTvFGVILGAVCGGLLRLaspIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAM 118
Cdd:PRK01663   3 KPLYKSLY-FQVLVAIIIGILLGH---FYPELGAQMKPLGDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGRVGGKAL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   119 VYYMSTTIIAAVLGVILVLAIHPGNpklkkqlgpgKKNDEVSSLDAfldlirnlfpenlvqacfQQIQTVTKKvlvappS 198
Cdd:PRK01663  79 LYFEIVSTIALIIGLIVVNVVQPGA----------GMNIDPATLDA------------------KAVAQYAAQ------A 124

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   199 EEANTTKAVISMLNETMNEApeetkivikkgleFKDGmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVI 278
Cdd:PRK01663 125 HEQGTVDFLMDIIPTTVVGA-------------FASG-DILQVLLFAVLFGFALARLGEKGKPVFDFIESLSHVLFGIVN 190

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   279 MIMWYSPLG----IACLIcGKIiAIKDLevvaRQLGMYMITVIVGLIIhggiFLPLIYFVVTRKNPFSFFAgiFQAWITA 354
Cdd:PRK01663 191 MIMKLAPIGafgaMAFTI-GKY-GVGSL----VQLGQLIGCFYITCIL----FVFVVLGAIARLTGFSIFK--FIRYIKE 258

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   355 -----LGTASSAGTLPVTFRCLEdNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTAT 429
Cdd:PRK01663 259 ellivLGTSSSESALPRMMEKME-KLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLL 337

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 7106409   430 LASIGAASIPSAGLVTMLLILTAVG-LPTEDISLLVAVDWLLDRMRTSVNVVGDSFgAGIVYHLSKSELDT 499
Cdd:PRK01663 338 LTSKGAAGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTNLIGNGV-ATVVVAKWEKELDR 407
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
40-489 7.18e-122

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 364.82  E-value: 7.18e-122
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   40 KNLLLSLTVFGVILGAVCGGLLrlaspiHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAM 118
Cdd:COG1301   2 KLSLTLQILIALVLGILLGLLL------PELVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409  119 VYYMSTTIIAAVLGVILVLAIHPGNPkLKKQLGPGKKNDEVSSLDaFLDLIRNLFPENLVQAcfqqiqtvtkkvlvapps 198
Cdd:COG1301  76 LYFLVTTTIALVIGLVVANLFQPGAG-LNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA------------------ 135

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409  199 eeanttkavismlnetmneapeetkivikkgleFKDGmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVI 278
Cdd:COG1301 136 ---------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVG 181

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409  279 MIMWYSPLGIACLIcGKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTA 358
Cdd:COG1301 182 WVMKLAPIGVFALI-AATVAKYGLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTS 259

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409  359 SSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASI 438
Cdd:COG1301 260 SSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGV 339

                       410       420       430       440       450
                ....*....|....*....|....*....|....*....|....*....|.
gi 7106409  439 PSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIV 489
Cdd:COG1301 340 PGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVV 390
SDF pfam00375
Sodium:dicarboxylate symporter family;
43-492 1.14e-121

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 363.38  E-value: 1.14e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409     43 LLSLTVFGVILGAVCGGLLrlaspihPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAMVYY 121
Cdd:pfam00375   1 LLLQILIALVLGILIGLFF-------PELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYF 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409    122 MSTTIIAAVLGVILVLAIHPGNPKLKKQLGPgkKNDEVSSLDAFLDLIRNLFPENLVQACFQQiqtvtkkvlvappseea 201
Cdd:pfam00375  74 LVTTAIAALIGLLVANVFQPGSGLALIAASL--KEAKAAEAPSLLDFILNIIPSNIFEALAEG----------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409    202 nttkavismlnetmneapeetkivikkglefkdgmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIM 281
Cdd:pfam00375 135 -----------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVM 179

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409    282 WYSPLGIACLICgKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSA 361
Cdd:pfam00375 180 KLAPIGVFALIA-NTVGTYGLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSA 257

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409    362 GTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSA 441
Cdd:pfam00375 258 ATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGG 337

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 7106409    442 GLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL 492
Cdd:pfam00375 338 GLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 40-499 4.58e-40

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 150.82  E-value: 4.58e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409    40 KNLLLSLTvFGVILGAVCGGLLRLaspIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAM 118
Cdd:PRK01663   3 KPLYKSLY-FQVLVAIIIGILLGH---FYPELGAQMKPLGDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGRVGGKAL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   119 VYYMSTTIIAAVLGVILVLAIHPGNpklkkqlgpgKKNDEVSSLDAfldlirnlfpenlvqacfQQIQTVTKKvlvappS 198
Cdd:PRK01663  79 LYFEIVSTIALIIGLIVVNVVQPGA----------GMNIDPATLDA------------------KAVAQYAAQ------A 124

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   199 EEANTTKAVISMLNETMNEApeetkivikkgleFKDGmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVI 278
Cdd:PRK01663 125 HEQGTVDFLMDIIPTTVVGA-------------FASG-DILQVLLFAVLFGFALARLGEKGKPVFDFIESLSHVLFGIVN 190

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   279 MIMWYSPLG----IACLIcGKIiAIKDLevvaRQLGMYMITVIVGLIIhggiFLPLIYFVVTRKNPFSFFAgiFQAWITA 354
Cdd:PRK01663 191 MIMKLAPIGafgaMAFTI-GKY-GVGSL----VQLGQLIGCFYITCIL----FVFVVLGAIARLTGFSIFK--FIRYIKE 258

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   355 -----LGTASSAGTLPVTFRCLEdNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTAT 429
Cdd:PRK01663 259 ellivLGTSSSESALPRMMEKME-KLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLL 337

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 7106409   430 LASIGAASIPSAGLVTMLLILTAVG-LPTEDISLLVAVDWLLDRMRTSVNVVGDSFgAGIVYHLSKSELDT 499
Cdd:PRK01663 338 LTSKGAAGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTNLIGNGV-ATVVVAKWEKELDR 407
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
 40-483 3.46e-39

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 148.76  E-value: 3.46e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409    40 KNLLLSLT---VFGVILGAVCGGLLRLASPIHPDVVMLIAFP-GDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLG 114
Cdd:PRK11283   2 KNIKFSLAwqiLIALVLGILLGAYLHYHSDSRDWLVSNLLSPaGDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   115 TRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGP------GKKNDEVSSLD-AFLDLIRNLFPENLVQAcfqqiqt 187
Cdd:PRK11283  82 AKTIIYFEVITTVAIILGITLANVFQPGAGIDMSQLATvdiskyQSTTEEVQSHShGLMGTILSLIPTNIFAS------- 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   188 vtkkvlvappseeanttkavismlnetmneapeetkivIKKGlefkdgmNVLGLIGFFIAFGIAMGKMGEQAKL-MVEFF 266
Cdd:PRK11283 155 --------------------------------------MAKG-------EMLPIIFFSVLFGLGLSSLPATHREpLVTVF 189

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   267 NILNEIVMKLVIMIMWYSPLGIACLIcgkiiaikdlEVVARQLGMYMITVIVGLII--HGGI--FLPLIYFVVTRKNPFS 342
Cdd:PRK11283 190 RSVSETMFKVTHMVMRYAPVGVFALI----------AVTVANFGFASLWPLAKLVLlvYFAIlfFALVVLGIVARLCGLS 259

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   343 FFAGIF---QAWITALGTASSAGTLPVTFRCLEdNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGG 419
Cdd:PRK11283 260 IWILIRilkDELILAYSTASSETVLPRIIEKME-AYGAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIW 338

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 7106409   420 QIVTVSLTATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDS 483
Cdd:PRK11283 339 QEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNA 402
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
 48-482 1.99e-35

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 137.49  E-value: 1.99e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409    48 VFGVILGAVCGGLLrlaspihPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAMVYYMSTTI 126
Cdd:PRK13027  13 VIALVLGVALGAFF-------PHFAESLKPLGDGFIKLIKMLIGPIVFCVVVSGIAGAgDLKKVGRVGLKAVIYFEVMTT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   127 IAAVLGVILVLAIHPGNpklkkqlgpgKKNDEVSSLDAfldlirnlfpenlvqacfQQIQTVTKKVlvappSEEANTTKA 206
Cdd:PRK13027  86 IALVIGLVLAYLTGPGV----------GMNIDLRSLDA------------------ASLAGYAKNA-----QSLKGTAGF 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   207 VISMLNETMNEApeetkivikkgleFKDGmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPL 286
Cdd:PRK13027 133 LLKLIPTTAVDA-------------FAKG-DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSHVLFRIMGFIIKLAPL 198

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   287 GIACLIC---GKIiAIKDLevvaRQLGMYMITVIVGLIIhggiFLPLIYFVVTRKNPFSFFAGIF---QAWITALGTASS 360
Cdd:PRK13027 199 GVLGAIAfttGKY-GVGSL----KQLGMLVAVFYLTCFV----FVVVVLGAVMRLAGFSVFKLIRylrEELLIVLGTASS 269

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   361 AGTLPVTFRCLEdNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPS 440
Cdd:PRK13027 270 DAVLPQVMRKLE-HMGIKDSTVGLVIPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVSLVTSKGAHGIPG 348

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|...
gi 7106409   441 AGLVTMLLILTAVG-LPTEDISLLVAVDWLLDRMRTSVNVVGD 482
Cdd:PRK13027 349 SAIVILAATLSAIPaIPVLGLVLILPVDWFMGIARALTNLIGN 391
TcyP COG1823
L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and ...
 40-489 3.80e-26

L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and metabolism];


Pssm-ID: 441428  Cd Length: 463  Bit Score: 111.46  E-value: 3.80e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   40 KNLLLSLTVF-GVILGAVCGGLLRLA----SPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRL 113
Cdd:COG1823  26 KHVSFSKRVFtGLGLGILFGLILQLIygagSPVIKQSIDWFNIVGNGYVRLLQMIVMPLVFVSILSAITKLkNASSLGKI 105

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409  114 GTRAMVYYMSTTIIAAVLGVILVLAIHpgnpklkkqlgpgkkndevssLDAfldlirnlfpENLVQAcfqqiqtvtkkvl 193
Cdd:COG1823 106 SGLIIGILLGTTAIAALVGILVALLFG---------------------LTA----------EGLTQG------------- 141

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409  194 vappseEANTTKavISMLNETMNEAPEETkiVIKKGLE------FKD--GMNVLGLIG--FFIAF-GIA----MGKMGEQ 258
Cdd:COG1823 142 ------AAETAR--GEALEERLGEVEDLS--LPQQILSfiptnpFADltGARPTSTIAvvIFAAFlGIAalglRRKKPEQ 211

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409  259 AKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICgKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIyfVVTRK 338
Cdd:COG1823 212 AETFLKGIDALQAIVMRLVRLVLRLTPYGVLALMT-KVVATSDFADIL-NLGKFVVASYVALIIMFIVHLLLL--ALAGL 287

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409  339 NPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTA-LYEAVAAIFIAQMNGV-IL 416
Cdd:COG1823 288 NPLTYFKKVWPVLTFAFTSRSSAGTIPLNIETQTKRLGVPEGIANFAASFGATIGQNGCAgIYPAMLAVMIAPTVGInPL 367

                       410       420       430       440       450       460       470
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 7106409  417 DGGQIVTVSLTATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNvVGDSFGAGIV 489
Cdd:COG1823 368 DPSFILTLIAVVTISSFGVAGVGGGATFAALIVLSAMGLPVALAGLLISIEPLIDMGRTALN-VSGSMTAGTV 439
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
 237-483 1.89e-14

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 74.32  E-value: 1.89e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   237 NVLGLIGFFIAFGIAMGKMGEQAKlmvEFFNILNEIVMKLVIMIMWYSPLGIACLICgKIIAIKDLEVVArQLGMYMITV 316
Cdd:PRK14695  60 NYIGILSWAVIFGIAMREASKNSK---ELLKTIADVTSKIVEWIINLAPFGILGLVF-KTISDKGVGSLA-NYGILLVLL 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   317 IVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQ-AWITALGTASSAGTLPVTFRCLEDnLGIDKRVTRFVLPVGATINMD 395
Cdd:PRK14695 135 VTTMLFVAPVVNPLIAFFFMRRNPYPLVWNCLRvSGVTAFFTRSSATNIPVNMKLCHD-LGLNPDTYSVSIPLGSTINMA 213

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   396 GTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRT 475
Cdd:PRK14695 214 GVAITINLLTLVTVNTLGIPVDFATAFVLSVVAAISACGASGIAGGSLLLIPVACSLFGISNDIAIQIVGVGFVIGVIQD 293


                 ....*...
gi 7106409   476 SVNVVGDS 483
Cdd:PRK14695 294 SCETALNS 301
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
 237-455 9.86e-12

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 66.81  E-value: 9.86e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   237 NVLGLIGFFIAFGIAMGKMGEQAKlmvEFFNILNEIVMKLVIMIMWYSPLGIACLICGkIIAIKDLEVVAR--QLGMYMI 314
Cdd:PRK13628 146 NYIGILAWAIGLGLALRHASDTTK---NVVNDLSEAVSQIVKWVIRFAPIGIFGLVAS-TLAETGFSALAGyaQLLAVLV 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409   315 T--VIVGLIIHggiflPLIYFVVTRKNPFSF-FAGIFQAWITALGTASSAGTLPVTFRCLEDnLGIDKRVTRFVLPVGAT 391
Cdd:PRK13628 222 GcmLFVALVVN-----PLIVFWKIRRNPYPLvFTCLRESGVTAFFTRSSAANIPVNMALCEK-LGLDEDTYSVSIPLGAT 295

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 7106409   392 INMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSAGLvtmLLILTAVGL 455
Cdd:PRK13628 296 INMAGAAITITVLTLAAVHTLGIPVDLPTALLLSVVAAISACGASGVAGGSL---LLIPLACSL 356
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
237-455 2.82e-10

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 62.50  E-value: 2.82e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409  237 NVLGLIGFFIAFGIAMGKMGEQAKLMvefFNILNEIVMKLVIMIMWYSPLGIACLICGkIIAIKDLEVvarqLGMY--MI 314
Cdd:COG3633 145 NYIGILAWAIGLGLALRHASDTTKTV---LSDLSDAVSKIVRWVIRFAPLGIFGLVAS-TVATTGFSA----LLGYahLL 216

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106409  315 TVIVG------LIIHggiflPLIYFVVTRKNPFSF-FAGIFQAWITALGTASSAGTLPVTFRCLEDnLGIDKRVTRFVLP 387
Cdd:COG3633 217 AVLVGcmlfvaLVVN-----PLIVFLKIRRNPYPLvFTCLRESGITAFFTRSSAANIPVNMALCEK-LGLDEDTYSVSIP 290

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 7106409  388 VGATINMDGtalyeavAAIFIAQMN-------GVILDGGQIVTVSLTATLASIGAASIPSAGLvtmLLILTAVGL 455
Cdd:COG3633 291 LGATINMAG-------AAITITVLTlaavhtlGIEVDLPTALLLSVVAAVSACGASGVAGGSL---LLIPLACSL 355
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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