|
Name |
Accession |
Description |
Interval |
E-value |
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
400-517 |
4.88e-26 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
:
Pssm-ID: 214804 Cd Length: 118 Bit Score: 103.58 E-value: 4.88e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6753418 400 DVLQSVLCGADALIPVQTGAAGSASFILLGNGSLIYQVQVVGTGSEVVAMTLETKPQRKN---QRTVLCHMaglQPGGHM 476
Cdd:smart00754 1 ETFSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPETAAHIHEGEIGTNgpvVRIPLPNP---TSREGP 77
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 6753418 477 AVGMCSGLGARGAHMLLQNELFLNVGTKDFPDGELRGHVTA 517
Cdd:smart00754 78 FAGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVAK 118
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
530-642 |
5.92e-26 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
:
Pssm-ID: 214804 Cd Length: 118 Bit Score: 103.19 E-value: 5.92e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6753418 530 LPVPLAGALVLPPVRSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQgtvTAHL-LGPPGMPGPQR--LLKGF--YGSEAQ 604
Cdd:smart00754 3 FSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPET---AAHIhEGEIGTNGPVVriPLPNPtsREGPFA 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 6753418 605 GVVKDLEPVLLRHLAQGTASLLITTKSSPRGELRGQVH 642
Cdd:smart00754 80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
170-273 |
7.74e-13 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
:
Pssm-ID: 214804 Cd Length: 118 Bit Score: 65.83 E-value: 7.74e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6753418 170 TDFVALLTG------PRSQAVARARVSLL-RSSLRFSVSYQRLDRPSRV-----RFTDPTG---NILFEHPATptQDGLV 234
Cdd:smart00754 1 ETFSALLTGsqevppVNTGAVGGAWFTLDdDGSLHYQVTLSGLSGPETAahiheGEIGTNGpvvRIPLPNPTS--REGPF 78
|
90 100 110
....*....|....*....|....*....|....*....
gi 6753418 235 CGVWRAVPRLSVRLLRAEQLRVALVTSTHPSGEVWGPLI 273
Cdd:smart00754 79 AGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
281-394 |
1.98e-12 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
:
Pssm-ID: 214804 Cd Length: 118 Bit Score: 64.67 E-value: 1.98e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6753418 281 ETFSAILTLE---DPLQRGVGGIALLTLsDTEDSLHFLLLFRGLLGGLAQAPLKL-QILHQGQLLRELQANTSAQEPGFA 356
Cdd:smart00754 1 ETFSALLTGSqevPPVNTGAVGGAWFTL-DDDGSLHYQVTLSGLSGPETAAHIHEgEIGTNGPVVRIPLPNPTSREGPFA 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 6753418 357 EVLPSLTDQEMDWLELGELQMVLEKAGGPELRISGYIT 394
Cdd:smart00754 80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
779-845 |
7.73e-07 |
|
von Willebrand factor (vWF) type C domain;
:
Pssm-ID: 214564 Cd Length: 59 Bit Score: 47.13 E-value: 7.73e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6753418 779 CYFDGDrsWRAAGTRWHPVVppfglikCAVCTCKGATgEVHCEKVQCPR-LACAQPVRANPTD-CCKQC 845
Cdd:smart00214 1 CVHNGR--VYNDGETWKPDP-------CQICTCLDGT-TVLCDPVECPPpPDCPNPERVKPPGeCCPRC 59
|
|
| VWC super family |
cl17735 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
51-125 |
3.12e-06 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
The actual alignment was detected with superfamily member pfam00093:
Pssm-ID: 450195 Cd Length: 57 Bit Score: 45.11 E-value: 3.12e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6753418 51 CSFGGKVYALDETWHPDLgepfgvmrCVLCACEapqwarrgrgPGRVSCKNIKpqCPTLACRQPR--QLPGHCCQTC 125
Cdd:pfam00093 1 CVQNGVVYENGETWKPDL--------CTICTCD----------DGKVLCDKII--CPPLDCPNPRleIPPGECCPVC 57
|
|
| VWC super family |
cl17735 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
867-927 |
3.56e-04 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
The actual alignment was detected with superfamily member pfam00093:
Pssm-ID: 450195 Cd Length: 57 Bit Score: 39.33 E-value: 3.56e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6753418 867 CRFAGQWFPENQSWHPSvppfgemSCITCRCGAGVPHCERDDCsPPLSCGSGKES----RCCSHC 927
Cdd:pfam00093 1 CVQNGVVYENGETWKPD-------LCTICTCDDGKVLCDKIIC-PPLDCPNPRLEippgECCPVC 57
|
|
| VWC super family |
cl17735 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
701-758 |
2.92e-03 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
The actual alignment was detected with superfamily member pfam00093:
Pssm-ID: 450195 Cd Length: 57 Bit Score: 36.63 E-value: 2.92e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 6753418 701 CFFEGQQRPHGARWAPNydpLCSLCICQRRTVICDPVVCPPPSCPHP--VQALDQCCPVC 758
Cdd:pfam00093 1 CVQNGVVYENGETWKPD---LCTICTCDDGKVLCDKIICPPLDCPNPrlEIPPGECCPVC 57
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
400-517 |
4.88e-26 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 103.58 E-value: 4.88e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6753418 400 DVLQSVLCGADALIPVQTGAAGSASFILLGNGSLIYQVQVVGTGSEVVAMTLETKPQRKN---QRTVLCHMaglQPGGHM 476
Cdd:smart00754 1 ETFSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPETAAHIHEGEIGTNgpvVRIPLPNP---TSREGP 77
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 6753418 477 AVGMCSGLGARGAHMLLQNELFLNVGTKDFPDGELRGHVTA 517
Cdd:smart00754 78 FAGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVAK 118
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
530-642 |
5.92e-26 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 103.19 E-value: 5.92e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6753418 530 LPVPLAGALVLPPVRSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQgtvTAHL-LGPPGMPGPQR--LLKGF--YGSEAQ 604
Cdd:smart00754 3 FSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPET---AAHIhEGEIGTNGPVVriPLPNPtsREGPFA 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 6753418 605 GVVKDLEPVLLRHLAQGTASLLITTKSSPRGELRGQVH 642
Cdd:smart00754 80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
pfam07452 |
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in ... |
530-641 |
2.36e-14 |
|
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..
Pssm-ID: 462167 Cd Length: 118 Bit Score: 70.20 E-value: 2.36e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6753418 530 LPVPLAGALVLPP-VRSQAAGHAWLSLDTHCH-LHYEVLLAGLggseQGTVTAHL-LGPPGMPGPQRL-----LKGFYGS 601
Cdd:pfam07452 1 FSALLTGAQEVPPpVTTGAGGTAVLTLDDTENtLHYTLTFSGL----SVPTAAHIhAGAAGFNGPVVVpleggPRKTTLL 76
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 6753418 602 EAQGVVKDLEPVLLRHLAQGTASLLIT--TKSSPRGELRGQV 641
Cdd:pfam07452 77 AVPEGLATLTAAQLAALLAQQGELYVNvhTEGNPGGEIRGQI 118
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
170-273 |
7.74e-13 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 65.83 E-value: 7.74e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6753418 170 TDFVALLTG------PRSQAVARARVSLL-RSSLRFSVSYQRLDRPSRV-----RFTDPTG---NILFEHPATptQDGLV 234
Cdd:smart00754 1 ETFSALLTGsqevppVNTGAVGGAWFTLDdDGSLHYQVTLSGLSGPETAahiheGEIGTNGpvvRIPLPNPTS--REGPF 78
|
90 100 110
....*....|....*....|....*....|....*....
gi 6753418 235 CGVWRAVPRLSVRLLRAEQLRVALVTSTHPSGEVWGPLI 273
Cdd:smart00754 79 AGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
281-394 |
1.98e-12 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 64.67 E-value: 1.98e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6753418 281 ETFSAILTLE---DPLQRGVGGIALLTLsDTEDSLHFLLLFRGLLGGLAQAPLKL-QILHQGQLLRELQANTSAQEPGFA 356
Cdd:smart00754 1 ETFSALLTGSqevPPVNTGAVGGAWFTL-DDDGSLHYQVTLSGLSGPETAAHIHEgEIGTNGPVVRIPLPNPTSREGPFA 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 6753418 357 EVLPSLTDQEMDWLELGELQMVLEKAGGPELRISGYIT 394
Cdd:smart00754 80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
pfam07452 |
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in ... |
402-515 |
4.68e-12 |
|
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..
Pssm-ID: 462167 Cd Length: 118 Bit Score: 63.65 E-value: 4.68e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6753418 402 LQSVLCGADALIP-VQTGAAGSASFIL-LGNGSLIYQVQVVGTG--------------SEVVAMTLETKPQRKNQRTVlc 465
Cdd:pfam07452 1 FSALLTGAQEVPPpVTTGAGGTAVLTLdDTENTLHYTLTFSGLSvptaahihagaagfNGPVVVPLEGGPRKTTLLAV-- 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 6753418 466 hmaglqpgghmaVGMCSGLGARGAHMLLQN--ELFLNVGTKDFPDGELRGHV 515
Cdd:pfam07452 79 ------------PEGLATLTAAQLAALLAQqgELYVNVHTEGNPGGEIRGQI 118
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
779-845 |
7.73e-07 |
|
von Willebrand factor (vWF) type C domain;
Pssm-ID: 214564 Cd Length: 59 Bit Score: 47.13 E-value: 7.73e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6753418 779 CYFDGDrsWRAAGTRWHPVVppfglikCAVCTCKGATgEVHCEKVQCPR-LACAQPVRANPTD-CCKQC 845
Cdd:smart00214 1 CVHNGR--VYNDGETWKPDP-------CQICTCLDGT-TVLCDPVECPPpPDCPNPERVKPPGeCCPRC 59
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
51-125 |
3.12e-06 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 45.11 E-value: 3.12e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6753418 51 CSFGGKVYALDETWHPDLgepfgvmrCVLCACEapqwarrgrgPGRVSCKNIKpqCPTLACRQPR--QLPGHCCQTC 125
Cdd:pfam00093 1 CVQNGVVYENGETWKPDL--------CTICTCD----------DGKVLCDKII--CPPLDCPNPRleIPPGECCPVC 57
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
867-927 |
3.56e-04 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 39.33 E-value: 3.56e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6753418 867 CRFAGQWFPENQSWHPSvppfgemSCITCRCGAGVPHCERDDCsPPLSCGSGKES----RCCSHC 927
Cdd:pfam00093 1 CVQNGVVYENGETWKPD-------LCTICTCDDGKVLCDKIIC-PPLDCPNPRLEippgECCPVC 57
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
701-758 |
2.92e-03 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 36.63 E-value: 2.92e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 6753418 701 CFFEGQQRPHGARWAPNydpLCSLCICQRRTVICDPVVCPPPSCPHP--VQALDQCCPVC 758
Cdd:pfam00093 1 CVQNGVVYENGETWKPD---LCTICTCDDGKVLCDKIICPPLDCPNPrlEIPPGECCPVC 57
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
400-517 |
4.88e-26 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 103.58 E-value: 4.88e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6753418 400 DVLQSVLCGADALIPVQTGAAGSASFILLGNGSLIYQVQVVGTGSEVVAMTLETKPQRKN---QRTVLCHMaglQPGGHM 476
Cdd:smart00754 1 ETFSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPETAAHIHEGEIGTNgpvVRIPLPNP---TSREGP 77
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 6753418 477 AVGMCSGLGARGAHMLLQNELFLNVGTKDFPDGELRGHVTA 517
Cdd:smart00754 78 FAGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVAK 118
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
530-642 |
5.92e-26 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 103.19 E-value: 5.92e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6753418 530 LPVPLAGALVLPPVRSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQgtvTAHL-LGPPGMPGPQR--LLKGF--YGSEAQ 604
Cdd:smart00754 3 FSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPET---AAHIhEGEIGTNGPVVriPLPNPtsREGPFA 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 6753418 605 GVVKDLEPVLLRHLAQGTASLLITTKSSPRGELRGQVH 642
Cdd:smart00754 80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
pfam07452 |
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in ... |
530-641 |
2.36e-14 |
|
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..
Pssm-ID: 462167 Cd Length: 118 Bit Score: 70.20 E-value: 2.36e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6753418 530 LPVPLAGALVLPP-VRSQAAGHAWLSLDTHCH-LHYEVLLAGLggseQGTVTAHL-LGPPGMPGPQRL-----LKGFYGS 601
Cdd:pfam07452 1 FSALLTGAQEVPPpVTTGAGGTAVLTLDDTENtLHYTLTFSGL----SVPTAAHIhAGAAGFNGPVVVpleggPRKTTLL 76
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 6753418 602 EAQGVVKDLEPVLLRHLAQGTASLLIT--TKSSPRGELRGQV 641
Cdd:pfam07452 77 AVPEGLATLTAAQLAALLAQQGELYVNvhTEGNPGGEIRGQI 118
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
170-273 |
7.74e-13 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 65.83 E-value: 7.74e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6753418 170 TDFVALLTG------PRSQAVARARVSLL-RSSLRFSVSYQRLDRPSRV-----RFTDPTG---NILFEHPATptQDGLV 234
Cdd:smart00754 1 ETFSALLTGsqevppVNTGAVGGAWFTLDdDGSLHYQVTLSGLSGPETAahiheGEIGTNGpvvRIPLPNPTS--REGPF 78
|
90 100 110
....*....|....*....|....*....|....*....
gi 6753418 235 CGVWRAVPRLSVRLLRAEQLRVALVTSTHPSGEVWGPLI 273
Cdd:smart00754 79 AGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
281-394 |
1.98e-12 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 64.67 E-value: 1.98e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6753418 281 ETFSAILTLE---DPLQRGVGGIALLTLsDTEDSLHFLLLFRGLLGGLAQAPLKL-QILHQGQLLRELQANTSAQEPGFA 356
Cdd:smart00754 1 ETFSALLTGSqevPPVNTGAVGGAWFTL-DDDGSLHYQVTLSGLSGPETAAHIHEgEIGTNGPVVRIPLPNPTSREGPFA 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 6753418 357 EVLPSLTDQEMDWLELGELQMVLEKAGGPELRISGYIT 394
Cdd:smart00754 80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
pfam07452 |
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in ... |
402-515 |
4.68e-12 |
|
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..
Pssm-ID: 462167 Cd Length: 118 Bit Score: 63.65 E-value: 4.68e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6753418 402 LQSVLCGADALIP-VQTGAAGSASFIL-LGNGSLIYQVQVVGTG--------------SEVVAMTLETKPQRKNQRTVlc 465
Cdd:pfam07452 1 FSALLTGAQEVPPpVTTGAGGTAVLTLdDTENTLHYTLTFSGLSvptaahihagaagfNGPVVVPLEGGPRKTTLLAV-- 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 6753418 466 hmaglqpgghmaVGMCSGLGARGAHMLLQN--ELFLNVGTKDFPDGELRGHV 515
Cdd:pfam07452 79 ------------PEGLATLTAAQLAALLAQqgELYVNVHTEGNPGGEIRGQI 118
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
779-845 |
7.73e-07 |
|
von Willebrand factor (vWF) type C domain;
Pssm-ID: 214564 Cd Length: 59 Bit Score: 47.13 E-value: 7.73e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6753418 779 CYFDGDrsWRAAGTRWHPVVppfglikCAVCTCKGATgEVHCEKVQCPR-LACAQPVRANPTD-CCKQC 845
Cdd:smart00214 1 CVHNGR--VYNDGETWKPDP-------CQICTCLDGT-TVLCDPVECPPpPDCPNPERVKPPGeCCPRC 59
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
51-125 |
3.12e-06 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 45.11 E-value: 3.12e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6753418 51 CSFGGKVYALDETWHPDLgepfgvmrCVLCACEapqwarrgrgPGRVSCKNIKpqCPTLACRQPR--QLPGHCCQTC 125
Cdd:pfam00093 1 CVQNGVVYENGETWKPDL--------CTICTCD----------DGKVLCDKII--CPPLDCPNPRleIPPGECCPVC 57
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
867-927 |
3.56e-04 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 39.33 E-value: 3.56e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6753418 867 CRFAGQWFPENQSWHPSvppfgemSCITCRCGAGVPHCERDDCsPPLSCGSGKES----RCCSHC 927
Cdd:pfam00093 1 CVQNGVVYENGETWKPD-------LCTICTCDDGKVLCDKIIC-PPLDCPNPRLEippgECCPVC 57
|
|
| Amnionless |
pfam14828 |
Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for ... |
41-125 |
7.93e-04 |
|
Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for vitamin B12 uptake.
Pssm-ID: 464340 Cd Length: 449 Bit Score: 43.15 E-value: 7.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6753418 41 EPLPVRGAagcSFGGKVYALDETWHPDLGEPFGVM----------------RCVLCAC---EAPQWArrgrgpgrvsCKN 101
Cdd:pfam14828 145 RPIRVKSV---SLLGQTFTSDEDFAEFLSSRLGQLqfhgagalrvgpeacsDPSGCGCgndENLERI----------CAN 211
|
90 100
....*....|....*....|....
gi 6753418 102 IKPQCPTLACRQPRQLPGHCCQTC 125
Cdd:pfam14828 212 VLQRCPPPHCLSPLRPEGHCCDVC 235
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
701-758 |
2.92e-03 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 36.63 E-value: 2.92e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 6753418 701 CFFEGQQRPHGARWAPNydpLCSLCICQRRTVICDPVVCPPPSCPHP--VQALDQCCPVC 758
Cdd:pfam00093 1 CVQNGVVYENGETWKPD---LCTICTCDDGKVLCDKIICPPLDCPNPrlEIPPGECCPVC 57
|
|
| |
