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Conserved domains on  [gi|114326474|ref|NP_033227|]
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neutral amino acid transporter B(0) [Mus musculus]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10003465)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
55-493 3.84e-113

Na+/H+-dicarboxylate symporter [Energy production and conversion];


:

Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 342.09  E-value: 3.84e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474  55 LVLLTVAAVVAGVGLGLgvsaaggadALGPARLTAFAFPGELLLRLLKMIILPLVVCSLIGGAASL-DPSALGRVGAWAL 133
Cdd:COG1301    5 LTLQILIALVLGILLGL---------LLPELVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 134 LFFLVTTLLASALGVGLALALKPGAAVTaitsindsvVDPCARSAPTKEVLDSFLDLVRNIFPSNLVSAAfrsfatsyep 213
Cdd:COG1301   76 LYFLVTTTIALVIGLVVANLFQPGAGLN---------LDLADAAAAEAAEAPSLLDFLLNIIPSNIFEAF---------- 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 214 kdnsckipqsciqreinstmvqllceVEGmNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNDATMVLVSWIMWYAPV 293
Cdd:COG1301  137 --------------------------AEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPI 189

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 294 GILFLVASKIVEMKDvrQLFISLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIMTPLATAFGTSSSSATLPL 373
Cdd:COG1301  190 GVFALIAATVAKYGL--DALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPV 267

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 374 MMKCVEEKNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLNGVSLDFVKIITILVTATASSVGAAGIPAGGVLTL 453
Cdd:COG1301  268 TMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVML 347

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|
gi 114326474 454 AIILEAVSLPVKDISLILAVDWLVDRSCTVLNVEGDAFGA 493
Cdd:COG1301  348 AAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVAT 387
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
55-493 3.84e-113

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 342.09  E-value: 3.84e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474  55 LVLLTVAAVVAGVGLGLgvsaaggadALGPARLTAFAFPGELLLRLLKMIILPLVVCSLIGGAASL-DPSALGRVGAWAL 133
Cdd:COG1301    5 LTLQILIALVLGILLGL---------LLPELVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 134 LFFLVTTLLASALGVGLALALKPGAAVTaitsindsvVDPCARSAPTKEVLDSFLDLVRNIFPSNLVSAAfrsfatsyep 213
Cdd:COG1301   76 LYFLVTTTIALVIGLVVANLFQPGAGLN---------LDLADAAAAEAAEAPSLLDFLLNIIPSNIFEAF---------- 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 214 kdnsckipqsciqreinstmvqllceVEGmNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNDATMVLVSWIMWYAPV 293
Cdd:COG1301  137 --------------------------AEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPI 189

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 294 GILFLVASKIVEMKDvrQLFISLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIMTPLATAFGTSSSSATLPL 373
Cdd:COG1301  190 GVFALIAATVAKYGL--DALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPV 267

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 374 MMKCVEEKNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLNGVSLDFVKIITILVTATASSVGAAGIPAGGVLTL 453
Cdd:COG1301  268 TMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVML 347

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|
gi 114326474 454 AIILEAVSLPVKDISLILAVDWLVDRSCTVLNVEGDAFGA 493
Cdd:COG1301  348 AAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVAT 387
SDF pfam00375
Sodium:dicarboxylate symporter family;
55-496 4.25e-109

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 331.02  E-value: 4.25e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474   55 LVLLTVAAVVAGVGLGLgvsaaggadaLGPARLTAFAFPGELLLRLLKMIILPLVVCSLIGGAASL-DPSALGRVGAWAL 133
Cdd:pfam00375   1 LLLQILIALVLGILIGL----------FFPELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTL 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474  134 LFFLVTTLLASALGVGLALALKPGAAVTAITSINDSVVDPcarsaptkeVLDSFLDLVRNIFPSNLVSAAFRSfatsyep 213
Cdd:pfam00375  71 LYFLVTTAIAALIGLLVANVFQPGSGLALIAASLKEAKAA---------EAPSLLDFILNIIPSNIFEALAEG------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474  214 kdnsckipqsciqreinstmvqllcevegmNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNDATMVLVSWIMWYAPV 293
Cdd:pfam00375 135 ------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPI 184

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474  294 GILFLVASKIVEMkdVRQLFISLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIMTPLATAFGTSSSSATLPL 373
Cdd:pfam00375 185 GVFALIANTVGTY--GLGILSSLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPV 262

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474  374 MMKCVEEKNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLNGVSLDFVKIITILVTATASSVGAAGIPAGGVLTL 453
Cdd:pfam00375 263 TLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVAL 342

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 114326474  454 AIILEAVSLPVKDISLILAVDWLVDRSCTVLNVEGDAFGAGLL 496
Cdd:pfam00375 343 GLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIV 385
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 60-477 3.53e-40

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 151.21  E-value: 3.53e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474  60 VAAVVAGVGLGlgvsaaggadALGPARLTAFAFPGELLLRLLKMIILPLVVCSLIGGAASL-DPSALGRVGAWALLFFLV 138
Cdd:PRK01663  14 LVAIIIGILLG----------HFYPELGAQMKPLGDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGRVGGKALLYFEI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 139 TTLLASALGVGLALALKPGAAVtaitSINDSVVDPCARSAPTKEVLD-SFLDLVRNIFPSNLVSAafrsFATSyepkdns 217
Cdd:PRK01663  84 VSTIALIIGLIVVNVVQPGAGM----NIDPATLDAKAVAQYAAQAHEqGTVDFLMDIIPTTVVGA----FASG------- 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 218 ckipqsciqreinstmvqllcevegmNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNDATMVLVSWIMWYAPVGILF 297
Cdd:PRK01663 149 --------------------------DILQVLLFAVLFGFALARLGEKGKPVFDFIESLSHVLFGIVNMIMKLAPIGAFG 202

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 298 LVASKIVEMkDVRQLfISLGKYILCCLLGHAIHGLLVLPLI--YFLFtrkNPYRFLWGIMTPLATAFGTSSSSATLPLMM 375
Cdd:PRK01663 203 AMAFTIGKY-GVGSL-VQLGQLIGCFYITCILFVFVVLGAIarLTGF---SIFKFIRYIKEELLIVLGTSSSESALPRMM 277

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 376 KCVEeKNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLNGVSLDFVKIITILVTATASSVGAAGIPAGGVLTLAI 455
Cdd:PRK01663 278 EKME-KLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLLLTSKGAAGVTGSGFIVLAA 356

                        410       420
                 ....*....|....*....|...
gi 114326474 456 ILEAV-SLPVKDISLILAVDWLV 477
Cdd:PRK01663 357 TLSAVpHIPVAGLALILGIDRFM 379
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
55-493 3.84e-113

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 342.09  E-value: 3.84e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474  55 LVLLTVAAVVAGVGLGLgvsaaggadALGPARLTAFAFPGELLLRLLKMIILPLVVCSLIGGAASL-DPSALGRVGAWAL 133
Cdd:COG1301    5 LTLQILIALVLGILLGL---------LLPELVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 134 LFFLVTTLLASALGVGLALALKPGAAVTaitsindsvVDPCARSAPTKEVLDSFLDLVRNIFPSNLVSAAfrsfatsyep 213
Cdd:COG1301   76 LYFLVTTTIALVIGLVVANLFQPGAGLN---------LDLADAAAAEAAEAPSLLDFLLNIIPSNIFEAF---------- 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 214 kdnsckipqsciqreinstmvqllceVEGmNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNDATMVLVSWIMWYAPV 293
Cdd:COG1301  137 --------------------------AEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPI 189

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 294 GILFLVASKIVEMKDvrQLFISLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIMTPLATAFGTSSSSATLPL 373
Cdd:COG1301  190 GVFALIAATVAKYGL--DALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPV 267

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 374 MMKCVEEKNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLNGVSLDFVKIITILVTATASSVGAAGIPAGGVLTL 453
Cdd:COG1301  268 TMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVML 347

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|
gi 114326474 454 AIILEAVSLPVKDISLILAVDWLVDRSCTVLNVEGDAFGA 493
Cdd:COG1301  348 AAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVAT 387
SDF pfam00375
Sodium:dicarboxylate symporter family;
55-496 4.25e-109

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 331.02  E-value: 4.25e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474   55 LVLLTVAAVVAGVGLGLgvsaaggadaLGPARLTAFAFPGELLLRLLKMIILPLVVCSLIGGAASL-DPSALGRVGAWAL 133
Cdd:pfam00375   1 LLLQILIALVLGILIGL----------FFPELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTL 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474  134 LFFLVTTLLASALGVGLALALKPGAAVTAITSINDSVVDPcarsaptkeVLDSFLDLVRNIFPSNLVSAAFRSfatsyep 213
Cdd:pfam00375  71 LYFLVTTAIAALIGLLVANVFQPGSGLALIAASLKEAKAA---------EAPSLLDFILNIIPSNIFEALAEG------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474  214 kdnsckipqsciqreinstmvqllcevegmNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNDATMVLVSWIMWYAPV 293
Cdd:pfam00375 135 ------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPI 184

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474  294 GILFLVASKIVEMkdVRQLFISLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIMTPLATAFGTSSSSATLPL 373
Cdd:pfam00375 185 GVFALIANTVGTY--GLGILSSLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPV 262

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474  374 MMKCVEEKNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLNGVSLDFVKIITILVTATASSVGAAGIPAGGVLTL 453
Cdd:pfam00375 263 TLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVAL 342

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 114326474  454 AIILEAVSLPVKDISLILAVDWLVDRSCTVLNVEGDAFGAGLL 496
Cdd:pfam00375 343 GLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIV 385
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 60-477 3.53e-40

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 151.21  E-value: 3.53e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474  60 VAAVVAGVGLGlgvsaaggadALGPARLTAFAFPGELLLRLLKMIILPLVVCSLIGGAASL-DPSALGRVGAWALLFFLV 138
Cdd:PRK01663  14 LVAIIIGILLG----------HFYPELGAQMKPLGDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGRVGGKALLYFEI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 139 TTLLASALGVGLALALKPGAAVtaitSINDSVVDPCARSAPTKEVLD-SFLDLVRNIFPSNLVSAafrsFATSyepkdns 217
Cdd:PRK01663  84 VSTIALIIGLIVVNVVQPGAGM----NIDPATLDAKAVAQYAAQAHEqGTVDFLMDIIPTTVVGA----FASG------- 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 218 ckipqsciqreinstmvqllcevegmNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNDATMVLVSWIMWYAPVGILF 297
Cdd:PRK01663 149 --------------------------DILQVLLFAVLFGFALARLGEKGKPVFDFIESLSHVLFGIVNMIMKLAPIGAFG 202

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 298 LVASKIVEMkDVRQLfISLGKYILCCLLGHAIHGLLVLPLI--YFLFtrkNPYRFLWGIMTPLATAFGTSSSSATLPLMM 375
Cdd:PRK01663 203 AMAFTIGKY-GVGSL-VQLGQLIGCFYITCILFVFVVLGAIarLTGF---SIFKFIRYIKEELLIVLGTSSSESALPRMM 277

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 376 KCVEeKNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLNGVSLDFVKIITILVTATASSVGAAGIPAGGVLTLAI 455
Cdd:PRK01663 278 EKME-KLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLLLTSKGAAGVTGSGFIVLAA 356

                        410       420
                 ....*....|....*....|...
gi 114326474 456 ILEAV-SLPVKDISLILAVDWLV 477
Cdd:PRK01663 357 TLSAVpHIPVAGLALILGIDRFM 379
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
 94-522 8.35e-35

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 136.05  E-value: 8.35e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474  94 GELLLRLLKMIILPLVVCSLIGGAASL-DPSALGRVGAWALLFFLVTTLLASALGVGLALALKPGAAVTAITSindSVVD 172
Cdd:PRK11283  45 GDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIGAKTIIYFEVITTVAIILGITLANVFQPGAGIDMSQL---ATVD 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 173 PCARSAPTKEVLD---SFLDLVRNIFPSNLVSAAFRSfatsyepkdnsckipqsciqreinstmvqllcevegmNILGLV 249
Cdd:PRK11283 122 ISKYQSTTEEVQShshGLMGTILSLIPTNIFASMAKG-------------------------------------EMLPII 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 250 VFAIVFGVALRKLGPE-GELLIRFFNSFNDATMVLVSWIMWYAPVGILFLVASKIVEMKDVRqlFISLGKYILCCLLGHA 328
Cdd:PRK11283 165 FFSVLFGLGLSSLPAThREPLVTVFRSVSETMFKVTHMVMRYAPVGVFALIAVTVANFGFAS--LWPLAKLVLLVYFAIL 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 329 IHGLLVLPLIYFLFtRKNPYRFLWGIMTPLATAFGTSSSSATLPLMMKCVEeKNGVAKHISRFILPIGATVNMDGAALFQ 408
Cdd:PRK11283 243 FFALVVLGIVARLC-GLSIWILIRILKDELILAYSTASSETVLPRIIEKME-AYGAPKSITSFVVPTGYSFNLDGSTLYQ 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 409 CVAAVFIAQLNGVSLDFVKIITILVTATASSVGAAGIPAGGVLTLAIILEAVSLPVKDISLILAVDWLVDRSCTVLNVEG 488
Cdd:PRK11283 321 SIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVG 400

                        410       420       430
                 ....*....|....*....|....*....|....*..
gi 114326474 489 DAFGAGLLQSY---VDRTKMPSSEPELIQVKNEVSLN 522
Cdd:PRK11283 401 NALAVLVIAKWehkFDRKKALAYEREVLGKFDKTADQ 437
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
 47-477 3.89e-33

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 130.94  E-value: 3.89e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474  47 RRCIRAnlLVLLTVAAVVAGVGLGLGvsAAGGADALGPArltafafpGELLLRLLKMIILPLVVCSLIGGAASL-DPSAL 125
Cdd:PRK13027   2 KKFLRS--LFGQVVIALVLGVALGAF--FPHFAESLKPL--------GDGFIKLIKMLIGPIVFCVVVSGIAGAgDLKKV 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 126 GRVGAWALLFFLVTTLLASALGVGLALALKPGAAVtaitSINDSVVDPCARSAPTK--EVLDSFLDLVRNIFPSNLVSAa 203
Cdd:PRK13027  70 GRVGLKAVIYFEVMTTIALVIGLVLAYLTGPGVGM----NIDLRSLDAASLAGYAKnaQSLKGTAGFLLKLIPTTAVDA- 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 204 frsFATSyepkdnsckipqsciqreinstmvqllcevegmNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNDATMVL 283
Cdd:PRK13027 145 ---FAKG---------------------------------DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSHVLFRI 188

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 284 VSWIMWYAPVGILFLVASKIVE--MKDVRQLFISLGKYILCCL------LGHA--IHGLLVLPLIYFLftrknpyrflwg 353
Cdd:PRK13027 189 MGFIIKLAPLGVLGAIAFTTGKygVGSLKQLGMLVAVFYLTCFvfvvvvLGAVmrLAGFSVFKLIRYL------------ 256

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 354 iMTPLATAFGTSSSSATLPLMMKCVEeKNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLNGVSLDFVKIITILV 433
Cdd:PRK13027 257 -REELLIVLGTASSDAVLPQVMRKLE-HMGIKDSTVGLVIPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILL 334

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*
gi 114326474 434 TATASSVGAAGIPAGGVLTLAIILEAV-SLPVKDISLILAVDWLV 477
Cdd:PRK13027 335 VSLVTSKGAHGIPGSAIVILAATLSAIpAIPVLGLVLILPVDWFM 379
TcyP COG1823
L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and ...
 61-498 1.44e-26

L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and metabolism];


Pssm-ID: 441428  Cd Length: 463  Bit Score: 112.61  E-value: 1.44e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474  61 AAVVAGVGLGLGVSAAGGAD-ALGPARLTAFAFPGELLLRLLKMIILPLVVCSLIGGAASL-DPSALGRVGAWALLFFLV 138
Cdd:COG1823   36 TGLGLGILFGLILQLIYGAGsPVIKQSIDWFNIVGNGYVRLLQMIVMPLVFVSILSAITKLkNASSLGKISGLIIGILLG 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 139 TTLLASALGVGLALA-------LKPGAAVTA-ITSINDSVVDPCARSAPtkevldsflDLVRNIFPSNlvsaAFRSFATS 210
Cdd:COG1823  116 TTAIAALVGILVALLfgltaegLTQGAAETArGEALEERLGEVEDLSLP---------QQILSFIPTN----PFADLTGA 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 211 yepkdnsckipqsciqreiNSTmvqllcevegmNILGLVVFAIVFGVA---LRKLGPE-GELLIRFFNSFNDATMVLVSW 286
Cdd:COG1823  183 -------------------RPT-----------STIAVVIFAAFLGIAalgLRRKKPEqAETFLKGIDALQAIVMRLVRL 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 287 IMWYAPVGILFLVAsKIVEMKDVRQLfISLGKYILCCLLGHAIhgLLVLPLIYFLFTRKNPYRFLWGIMTPLATAFGTSS 366
Cdd:COG1823  233 VLRLTPYGVLALMT-KVVATSDFADI-LNLGKFVVASYVALII--MFIVHLLLLALAGLNPLTYFKKVWPVLTFAFTSRS 308

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 367 SSATLPLMMKCVEEKNGVAKHISRFILPIGATVNMDG-AALFQCVAAVFIAQLNGVS-LDFVKIITILVTATASSVGAAG 444
Cdd:COG1823  309 SAGTIPLNIETQTKRLGVPEGIANFAASFGATIGQNGcAGIYPAMLAVMIAPTVGINpLDPSFILTLIAVVTISSFGVAG 388

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 114326474 445 IpaGGVLTLA--IILEAVSLPVKDISLILAVDWLVDRSCTVLNVEGdAFGAGLLQS 498
Cdd:COG1823  389 V--GGGATFAalIVLSAMGLPVALAGLLISIEPLIDMGRTALNVSG-SMTAGTVTS 441
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
 244-453 7.51e-21

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 94.93  E-value: 7.51e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 244 NILGLVVFAIVFGVALRKLGPEGElliRFFNSFNDATMVLVSWIMWYAPVGILFLVASKIVEMKdvrqlFISLGKY--IL 321
Cdd:PRK13628 146 NYIGILAWAIGLGLALRHASDTTK---NVVNDLSEAVSQIVKWVIRFAPIGIFGLVASTLAETG-----FSALAGYaqLL 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 322 CCLLG-HAIHGLLVLPLIYFLFTRKNPYRFLW------GImtplaTAFGTSSSSATLPLMMK-CveEKNGVAKHISRFIL 393
Cdd:PRK13628 218 AVLVGcMLFVALVVNPLIVFWKIRRNPYPLVFtclresGV-----TAFFTRSSAANIPVNMAlC--EKLGLDEDTYSVSI 290

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 394 PIGATVNMDGAALFQCVAAVFIAQLNGVSLDFVKIITILVTATASSVGAAGIpAGGVLTL 453
Cdd:PRK13628 291 PLGATINMAGAAITITVLTLAAVHTLGIPVDLPTALLLSVVAAISACGASGV-AGGSLLL 349
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
244-453 4.77e-19

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 89.46  E-value: 4.77e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 244 NILGLVVFAIVFGVALRKLGPEGELLirfFNSFNDATMVLVSWIMWYAPVGILFLVASKIVEmkdvrQLFISLGKY--IL 321
Cdd:COG3633  145 NYIGILAWAIGLGLALRHASDTTKTV---LSDLSDAVSKIVRWVIRFAPLGIFGLVASTVAT-----TGFSALLGYahLL 216

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 322 CCLLG-HAIHGLLVLPLIYFLFTRKNPYRFLW------GImtplaTAFGTSSSSATLPLMMK-CveEKNGVAKHISRFIL 393
Cdd:COG3633  217 AVLVGcMLFVALVVNPLIVFLKIRRNPYPLVFtclresGI-----TAFFTRSSAANIPVNMAlC--EKLGLDEDTYSVSI 289

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 394 PIGATVNMDGAALFQCVAAVFIAQLNGVSLDFVKIITILVTATASSVGAAGIpAGGVLTL 453
Cdd:COG3633  290 PLGATINMAGAAITITVLTLAAVHTLGIEVDLPTALLLSVVAAVSACGASGV-AGGSLLL 348
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
 200-504 2.58e-18

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 85.87  E-value: 2.58e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 200 VSAAFRSFATSYEPKDNSCKIPQSCIQREINSTMVQLLCEvegmNILGLVVFAIVFGVALRKLGPEGELLIRffnSFNDA 279
Cdd:PRK14695  20 IEITLNSANTEIAPPDGIGQVLSNLLLKLVDSPVNALLTA----NYIGILSWAVIFGIAMREASKNSKELLK---TIADV 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 280 TMVLVSWIMWYAPVGILFLVAsKIVEMKDVRQLfISLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIM-TPL 358
Cdd:PRK14695  93 TSKIVEWIINLAPFGILGLVF-KTISDKGVGSL-ANYGILLVLLVTTMLFVAPVVNPLIAFFFMRRNPYPLVWNCLrVSG 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114326474 359 ATAFGTSSSSATLPLMMKCVEEKnGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLNGVSLDFVKIITILVTATAS 438
Cdd:PRK14695 171 VTAFFTRSSATNIPVNMKLCHDL-GLNPDTYSVSIPLGSTINMAGVAITINLLTLVTVNTLGIPVDFATAFVLSVVAAIS 249

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 114326474 439 SVGAAGIPAGGVLTLAI------ILEAVSLPVKDISLILAVdwLVDRSCTVLNVEGDAFGAGLLQSYVDRTK 504
Cdd:PRK14695 250 ACGASGIAGGSLLLIPVacslfgISNDIAIQIVGVGFVIGV--IQDSCETALNSSTDVLFTAVAEYAATRKK 319
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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