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Conserved domains on  [gi|6680363|ref|NP_032358|]
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interferon-induced protein with tetratricopeptide repeats 2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 152-282 1.50e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 76.19  E-value: 1.50e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  152 NQNERVKVCFQKALEKDPKNPEFTSGWAIANYRLDDWPArnyCIDSLEQAIQLSPDNTYVKVLLALKLDAVHK-NQAMAL 230
Cdd:COG3914  92 GRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEE---ALAALRRALALNPDFAEAYLNLGEALRRLGRlEEAIAA 168

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 6680363  231 VEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVHYYM 282
Cdd:COG3914 169 LRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 151-422 5.06e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 68.99  E-value: 5.06e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  151 KNQNERVKVCFQKALEKDPKNPEFTSGWAIANYRLDDWPArnyCIDSLEQAIQLSPDNTYVKVLLA-LKLDAVHKNQAMA 229
Cdd:COG2956  21 NGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDR---AIRIHQKLLERDPDRAEALLELAqDYLKAGLLDRAEE 97

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  230 LVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVHYYMGCCYRSKvhhmlnrremvfsGDRKKle 309
Cdd:COG2956  98 LLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQ-------------GDYDE-- 162

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  310 eliqlAVNHLRKAEEIKEMLEYSCSFLADLYIIAKKYDEADYYFQKELSKDlpPGPKQLLHLRYGNFQffQMKRQDKAIY 389
Cdd:COG2956 163 -----AIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQD--PDYLPALPRLAELYE--KLGDPEEALE 233

                       250       260       270       280
                ....*....|....*....|....*....|....*....|..
gi 6680363  390 HYMEGVKIKK---------KTIPQKKMREKLQRIALRRLHED 422
Cdd:COG2956 234 LLRKALELDPsddlllalaDLLERKEGLEAALALLERQLRRH 275
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 83-208 4.37e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.15  E-value: 4.37e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363   83 QQHPDQVEirslvTWGNYAWVYYHMGQFSKAQAYLDKVkqvckkfsspYRI--ENPALdcEEGWARLKCTKNQNERVKVC 160
Cdd:COG4235  11 AANPNDAE-----GWLLLGRAYLRLGRYDEALAAYEKA----------LRLdpDNADA--LLDLAEALLAAGDTEEAEEL 73

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 6680363  161 FQKALEKDPKNPEFTSGWAIANYRLDDWPArnyCIDSLEQAIQLSPDN 208
Cdd:COG4235  74 LERALALDPDNPEALYLLGLAAFQQGDYAE---AIAAWQKLLALLPAD 118
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 152-282 1.50e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 76.19  E-value: 1.50e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  152 NQNERVKVCFQKALEKDPKNPEFTSGWAIANYRLDDWPArnyCIDSLEQAIQLSPDNTYVKVLLALKLDAVHK-NQAMAL 230
Cdd:COG3914  92 GRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEE---ALAALRRALALNPDFAEAYLNLGEALRRLGRlEEAIAA 168

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 6680363  231 VEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVHYYM 282
Cdd:COG3914 169 LRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 151-422 5.06e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 68.99  E-value: 5.06e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  151 KNQNERVKVCFQKALEKDPKNPEFTSGWAIANYRLDDWPArnyCIDSLEQAIQLSPDNTYVKVLLA-LKLDAVHKNQAMA 229
Cdd:COG2956  21 NGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDR---AIRIHQKLLERDPDRAEALLELAqDYLKAGLLDRAEE 97

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  230 LVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVHYYMGCCYRSKvhhmlnrremvfsGDRKKle 309
Cdd:COG2956  98 LLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQ-------------GDYDE-- 162

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  310 eliqlAVNHLRKAEEIKEMLEYSCSFLADLYIIAKKYDEADYYFQKELSKDlpPGPKQLLHLRYGNFQffQMKRQDKAIY 389
Cdd:COG2956 163 -----AIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQD--PDYLPALPRLAELYE--KLGDPEEALE 233

                       250       260       270       280
                ....*....|....*....|....*....|....*....|..
gi 6680363  390 HYMEGVKIKK---------KTIPQKKMREKLQRIALRRLHED 422
Cdd:COG2956 234 LLRKALELDPsddlllalaDLLERKEGLEAALALLERQLRRH 275
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 145-359 1.05e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 51.24  E-value: 1.05e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363    145 ARLKCTKNQNERVKVCFQKALEKDPKNPEFTSGWAiANYRLDDWPARnyCIDSLEQAIQLSPDN-TYVKVLLALKLDAVH 223
Cdd:TIGR02917 540 AGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALA-QYYLGKGQLKK--ALAILNEAADAAPDSpEAWLMLGRAQLAAGD 616

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363    224 KNQAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAyvhyymgccyrskvhhMLNRREMVFSG 303
Cdd:TIGR02917 617 LNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNT----------------EAQIGLAQLLL 680

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 6680363    304 DRKKLEELIQLAvnhlRKAEEIKEMLEYSCSFLADLYIIAKKYDEADYYFQKELSK 359
Cdd:TIGR02917 681 AAKRTESAKKIA----KSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKR 732
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 83-208 4.37e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.15  E-value: 4.37e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363   83 QQHPDQVEirslvTWGNYAWVYYHMGQFSKAQAYLDKVkqvckkfsspYRI--ENPALdcEEGWARLKCTKNQNERVKVC 160
Cdd:COG4235  11 AANPNDAE-----GWLLLGRAYLRLGRYDEALAAYEKA----------LRLdpDNADA--LLDLAEALLAAGDTEEAEEL 73

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 6680363  161 FQKALEKDPKNPEFTSGWAIANYRLDDWPArnyCIDSLEQAIQLSPDN 208
Cdd:COG4235  74 LERALALDPDNPEALYLLGLAAFQQGDYAE---AIAAWQKLLALLPAD 118
TPR_19 pfam14559
Tetratricopeptide repeat;
225-279 1.45e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 39.87  E-value: 1.45e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 6680363    225 NQAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVH 279
Cdd:pfam14559   5 AEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYA 59
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 196-432 1.05e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.61  E-value: 1.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363    196 DSLEQAIQLSPDNTYVK-----VLLALKLDAV----HKNQAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLR 266
Cdd:TIGR02917 104 GKFQQVLDELPGKTLLDdegaaELLALRGLAYlglgQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALID 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363    267 KALEKLPNNAYVHYYMGCCYRSK--------------------VHHMLNR-----REMVFSGDRKKLEELIQLAVNHLrK 321
Cdd:TIGR02917 184 EVLTADPGNVDALLLKGDLLLSLgnielalaayrkaialrpnnIAVLLALatiliEAGEFEEAEKHADALLKKAPNSP-L 262

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363    322 AEEIKEMLEYScsfladlyiiAKKYDEADYYFQKELSKDlppgPKQLLHLRYGNFQFFQMKRQDKAIYHYMEGVKIKKKT 401
Cdd:TIGR02917 263 AHYLKALVDFQ----------KKNYEDARETLQDALKSA----PEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNS 328

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 6680363    402 IPQKKM------REKLQRIALRRLH----EDESDSEALHIL 432
Cdd:TIGR02917 329 HQARRLlasiqlRLGRVDEAIATLSpalgLDPDDPAALSLL 369
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 155-288 2.23e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.92  E-value: 2.23e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  155 ERVKVCFQKALEKDPKNPEFTSgwAIANYRLddwparnyCIDSLEQAIQlspdntYVKVLLALKLDAVHKNQAMALVEEA 234
Cdd:cd24142 143 QRCEELITKALELDPTNPEALQ--TLASLRI--------SQQRPDEAKE------ALRRSLELWKDLKEEDEEEAEEDEA 206

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 6680363  235 LKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVHYYMGCCYRS 288
Cdd:cd24142 207 EEEDVPSYEFRISLAKLLIELEMYEEALEVLEQLLDEDDEDVEVWYLLGWAYYL 260
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 226-340 2.39e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.92  E-value: 2.39e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  226 QAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVHY-YMG---------CCYRSKVHHMln 295
Cdd:cd24142  18 LALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYEKYlYLGqlsggeealQYYEKGIEIL-- 95

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*
gi 6680363  296 rremvfsgdRKKLEELIQLAVNHLRKAEEIKEMLEYSCSFLADLY 340
Cdd:cd24142  96 ---------EEELQALQAASAEAEEEAEELKRKLSSALCALAEIY 131
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 152-282 1.50e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 76.19  E-value: 1.50e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  152 NQNERVKVCFQKALEKDPKNPEFTSGWAIANYRLDDWPArnyCIDSLEQAIQLSPDNTYVKVLLALKLDAVHK-NQAMAL 230
Cdd:COG3914  92 GRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEE---ALAALRRALALNPDFAEAYLNLGEALRRLGRlEEAIAA 168

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 6680363  231 VEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVHYYM 282
Cdd:COG3914 169 LRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 151-422 5.06e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 68.99  E-value: 5.06e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  151 KNQNERVKVCFQKALEKDPKNPEFTSGWAIANYRLDDWPArnyCIDSLEQAIQLSPDNTYVKVLLA-LKLDAVHKNQAMA 229
Cdd:COG2956  21 NGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDR---AIRIHQKLLERDPDRAEALLELAqDYLKAGLLDRAEE 97

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  230 LVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVHYYMGCCYRSKvhhmlnrremvfsGDRKKle 309
Cdd:COG2956  98 LLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQ-------------GDYDE-- 162

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  310 eliqlAVNHLRKAEEIKEMLEYSCSFLADLYIIAKKYDEADYYFQKELSKDlpPGPKQLLHLRYGNFQffQMKRQDKAIY 389
Cdd:COG2956 163 -----AIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQD--PDYLPALPRLAELYE--KLGDPEEALE 233

                       250       260       270       280
                ....*....|....*....|....*....|....*....|..
gi 6680363  390 HYMEGVKIKK---------KTIPQKKMREKLQRIALRRLHED 422
Cdd:COG2956 234 LLRKALELDPsddlllalaDLLERKEGLEAALALLERQLRRH 275
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 160-276 1.04e-12

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 65.03  E-value: 1.04e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  160 CFQKALEKDPKNPEftsGW---AIANYRLDDWPArnyCIDSLEQAIQLSPDNTYVKVLLALKLDAVHKN-QAMALVEEAL 235
Cdd:COG4235   5 RLRQALAANPNDAE---GWlllGRAYLRLGRYDE---ALAAYEKALRLDPDNADALLDLAEALLAAGDTeEAEELLERAL 78

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 6680363  236 KKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNA 276
Cdd:COG4235  79 ALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADA 119
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 145-275 3.61e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 60.98  E-value: 3.61e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  145 ARLKCTKNQNERVKVCFQKALEKDPKNPEFTSGWAIANYRLDDWPARnycIDSLEQAIQLSPDNTYVKVLLALKLDAVHK 224
Cdd:COG4783  11 AQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEA---IVLLHEALELDPDEPEARLNLGLALLKAGD 87

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 6680363  225 -NQAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNN 275
Cdd:COG4783  88 yDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
96-377 4.34e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.10  E-value: 4.34e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363   96 TWGNYAWVYYHMGQFSKAQAyldkvkqvckkfsspyrienpaldceegwarlkctknqnervkvCFQKALEKDPKNPEFT 175
Cdd:COG0457  10 AYNNLGLAYRRLGRYEEAIE--------------------------------------------DYEKALELDPDDAEAL 45

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  176 SGWAIANYRLDDWPArnyCIDSLEQAIQLSPDNTYVKVLLALKLDAVHK-NQAMALVEEALKKDPSAIDTLLRAARFYCK 254
Cdd:COG0457  46 YNLGLAYLRLGRYEE---ALADYEQALELDPDDAEALNNLGLALQALGRyEEALEDYDKALELDPDDAEALYNLGLALLE 122

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  255 VYDTDRAIQLLRKALEKLPNNAYVHYYMGCCYRSKVHHMLNRREMVFSGDRKKLEELIQLAVNHLRKAEEIKEMLEYSCS 334
Cdd:COG0457 123 LGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLA 202

                       250       260       270       280
                ....*....|....*....|....*....|....*....|...
gi 6680363  335 FLADLYIIAKKYDEADYYFQKELSKDLPPGPKQLLHLRYGNFQ 377
Cdd:COG0457 203 LEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYRA 245
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
202-469 4.55e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 62.72  E-value: 4.55e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  202 IQLSPDNTYVKVLLALKLDAVHKNQ-AMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVHY 280
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEeAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  281 YMGCCYRskvhhmlnrremvfsgDRKKLEEliqlAVNHLRKAEEIKEMLEYSCSFLADLYIIAKKYDEADYYFQKELSKD 360
Cdd:COG0457  81 NLGLALQ----------------ALGRYEE----ALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELD 140

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  361 lppgPKQLLHLRYGNFQFFQMKRQDKAIYHYMEGVKIKKKTIPQKKMREKLQRIALRRLHEDESDSEALHILAFLQENGG 440
Cdd:COG0457 141 ----PDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTL 216

                       250       260
                ....*....|....*....|....*....
gi 6680363  441 GQQADKDSERGVDSANQVPSASLDEAGAE 469
Cdd:COG0457 217 AALAELLLLALALLLALRLAALALYQYRA 245
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 195-373 6.74e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 64.63  E-value: 6.74e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  195 IDSLEQAIQLSPDNTYVKVLLALKLDAVHK-NQAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLP 273
Cdd:COG3914  98 LALYRRALALNPDNAEALFNLGNLLLALGRlEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDP 177

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  274 NNAYVHYYMGCCYRskvhhmlnrremvfsgDRKKLEEliqlAVNHLRKAEEIKEMLEYSCSFLADLYIIAKKYDEADYYF 353
Cdd:COG3914 178 DNAEALNNLGNALQ----------------DLGRLEE----AIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFE 237

                       170       180
                ....*....|....*....|
gi 6680363  354 QKELSKDLPPGPKQLLHLRY 373
Cdd:COG3914 238 ELLAALARGPSELSPFALLY 257
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 179-287 3.09e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 55.20  E-value: 3.09e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  179 AIANYRLDDWPArnyCIDSLEQAIQLSPDNTYVKVLLA-LKLDAVHKNQAMALVEEALKKDPSAIDTLLRAARFYCKVYD 257
Cdd:COG4783  11 AQALLLAGDYDE---AEALLEKALELDPDNPEAFALLGeILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGD 87

                        90       100       110
                ....*....|....*....|....*....|
gi 6680363  258 TDRAIQLLRKALEKLPNNAYVHYYMGCCYR 287
Cdd:COG4783  88 YDEALALLEKALKLDPEHPEAYLRLARAYR 117
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 195-283 8.37e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 50.77  E-value: 8.37e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  195 IDSLEQAIQLSPDNTYVKVLLA-LKLDAVHKNQAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLP 273
Cdd:COG4235   3 IARLRQALAANPNDAEGWLLLGrAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDP 82

                        90
                ....*....|
gi 6680363  274 NNAYVHYYMG 283
Cdd:COG4235  83 DNPEALYLLG 92
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 103-271 2.26e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 52.04  E-value: 2.26e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  103 VYYHMGQFSKAQAYLDKVKQVCKkfsspyriENPALDCEegWARLKCTKNQNERVKVCFQKALEKDPKNPEFTSGWAIAN 182
Cdd:COG2956 119 IYEQEGDWEKAIEVLERLLKLGP--------ENAHAYCE--LAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELY 188

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  183 YRLDDWPArnyCIDSLEQAIQLSPDNTYVKVLLALKLDAVHKN-QAMALVEEALKKDPSaIDTLLRAARFYCKVYDTDRA 261
Cdd:COG2956 189 LEQGDYEE---AIAALERALEQDPDYLPALPRLAELYEKLGDPeEALELLRKALELDPS-DDLLLALADLLERKEGLEAA 264

                       170
                ....*....|
gi 6680363  262 IQLLRKALEK 271
Cdd:COG2956 265 LALLERQLRR 274
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
55-270 3.77e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 51.16  E-value: 3.77e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363   55 NILAYVKHCRGLNEAALQCLGEAEgfiqQQHPDQVEirslvTWGNYAWVYYHMGQFSKAQAYLDKVKQVCKKFSSPYRie 134
Cdd:COG0457  12 NNLGLAYRRLGRYEEAIEDYEKAL----ELDPDDAE-----ALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN-- 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  135 npaldceeGWARLKCTKNQNERVKVCFQKALEKDPKNPEFTSGWAIANYRLDDWPArnyCIDSLEQAIQLSPDNTYVKVL 214
Cdd:COG0457  81 --------NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDE---AIEAYERALELDPDDADALYN 149

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 6680363  215 LALKLDAVHK-NQAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALE 270
Cdd:COG0457 150 LGIALEKLGRyEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQA 206
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 226-365 6.12e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.46  E-value: 6.12e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  226 QAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVHYYMGCCYrskvhhmlnrremVFSGDR 305
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEAL-------------LAAGDT 67

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  306 KKleeliqlAVNHLRKAEEIKEMLEYSCSFLADLYIIAKKYDEADYYFQKELsKDLPPGP 365
Cdd:COG4235  68 EE-------AEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLL-ALLPADA 119
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 225-394 9.77e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 51.15  E-value: 9.77e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  225 NQAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVHYYMGCCYRskvhhmlnrremvfsgD 304
Cdd:COG3914  95 EEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALR----------------R 158

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  305 RKKLEEliqlAVNHLRKAEEIKEMLEYSCSFLADLYIIAKKYDEADYYFQK--ELSKDLPPGPKQLLHLRYGNFQFFQMK 382
Cdd:COG3914 159 LGRLEE----AIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRalELDPDNADAHSNLLFALRQACDWEVYD 234

                       170
                ....*....|..
gi 6680363  383 RQDKAIYHYMEG 394
Cdd:COG3914 235 RFEELLAALARG 246
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 145-359 1.05e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 51.24  E-value: 1.05e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363    145 ARLKCTKNQNERVKVCFQKALEKDPKNPEFTSGWAiANYRLDDWPARnyCIDSLEQAIQLSPDN-TYVKVLLALKLDAVH 223
Cdd:TIGR02917 540 AGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALA-QYYLGKGQLKK--ALAILNEAADAAPDSpEAWLMLGRAQLAAGD 616

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363    224 KNQAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAyvhyymgccyrskvhhMLNRREMVFSG 303
Cdd:TIGR02917 617 LNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNT----------------EAQIGLAQLLL 680

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 6680363    304 DRKKLEELIQLAvnhlRKAEEIKEMLEYSCSFLADLYIIAKKYDEADYYFQKELSK 359
Cdd:TIGR02917 681 AAKRTESAKKIA----KSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKR 732
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 240-398 2.16e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.11  E-value: 2.16e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  240 SAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVHYYMGCCYRskvhhmlnrremvfsgDRKKLEEliqlAVNHL 319
Cdd:COG4783   2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILL----------------QLGDLDE----AIVLL 61

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6680363  320 RKAEEIKEMLEYSCSFLADLYIIAKKYDEADYYFQKELSKDlPPGPKqlLHLRYGNFqFFQMKRQDKAIYHYMEGVKIK 398
Cdd:COG4783  62 HEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLD-PEHPE--AYLRLARA-YRALGRPDEAIAALEKALELD 136
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 172-391 2.25e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 49.99  E-value: 2.25e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  172 PEFTSGWAIANYRLDDWPARNYCIDSLEQAIQLSPDNTYVKVLLALKLDAVHK-------NQAMALVEEALKKDPSAIDT 244
Cdd:COG3914   1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEaaaaallALAAGEAAAAAAALLLLAAL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  245 LLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVHYYMGCCYRskvhhmlnrremvfsgDRKKLEEliqlAVNHLRKAEE 324
Cdd:COG3914  81 LELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLL----------------ALGRLEE----ALAALRRALA 140

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6680363  325 IKEMLEYSCSFLADLYIIAKKYDEADYYFQKELSKDlppgPKQL-LHLRYGNFqFFQMKRQDKAIYHY 391
Cdd:COG3914 141 LNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELD----PDNAeALNNLGNA-LQDLGRLEEAIAAY 203
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 150-359 2.61e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.08  E-value: 2.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363    150 TKNQNERVKvCFQKALEKDPKNPEftsgwaiANYRLDD--WPARNY--CIDSLEQAIQLSPDNTYVKVLLA-LKLDAVHK 224
Cdd:TIGR02917 614 AGDLNKAVS-SFKKLLALQPDSAL-------ALLLLADayAVMKNYakAITSLKRALELKPDNTEAQIGLAqLLLAAKRT 685

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363    225 NQAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVhyymgccyrSKVHHMLnrremVFSGD 304
Cdd:TIGR02917 686 ESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNA---------IKLHRAL-----LASGN 751

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 6680363    305 RKKLEELIQLAVNhlRKAEEIKEMLeyscsFLADLYIIAKKYDEADYYFQKELSK 359
Cdd:TIGR02917 752 TAEAVKTLEAWLK--THPNDAVLRT-----ALAELYLAQKDYDKAIKHYQTVVKK 799
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 83-208 4.37e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.15  E-value: 4.37e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363   83 QQHPDQVEirslvTWGNYAWVYYHMGQFSKAQAYLDKVkqvckkfsspYRI--ENPALdcEEGWARLKCTKNQNERVKVC 160
Cdd:COG4235  11 AANPNDAE-----GWLLLGRAYLRLGRYDEALAAYEKA----------LRLdpDNADA--LLDLAEALLAAGDTEEAEEL 73

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 6680363  161 FQKALEKDPKNPEFTSGWAIANYRLDDWPArnyCIDSLEQAIQLSPDN 208
Cdd:COG4235  74 LERALALDPDNPEALYLLGLAAFQQGDYAE---AIAAWQKLLALLPAD 118
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 103-360 7.17e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.54  E-value: 7.17e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363    103 VYYHMGQFSKAQAYLDKVKQVCKKFSSPYRIenpaldceegWARLKCTKNQNERVKVCFQKALEKDPKNPEFTSGWAIAN 182
Cdd:TIGR02917 304 SEYQLGNLEQAYQYLNQILKYAPNSHQARRL----------LASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAY 373

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363    183 YRLDDWP-ARNYcidsLEQAIQLSPDNTYVKVLLAL-KLDAVHKNQAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDR 260
Cdd:TIGR02917 374 LALGDFEkAAEY----LAKATELDPENAAARTQLGIsKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDK 449

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363    261 AIQLLRKALEKLPNNAYVHYYMGCCYrskvhhmLNRREMvfSGDRKKLEELIQLAVNHLRKAEEikemleyscsfLADLY 340
Cdd:TIGR02917 450 ALAAAKKLEKKQPDNASLHNLLGAIY-------LGKGDL--AKAREAFEKALSIEPDFFPAAAN-----------LARID 509

                         250       260
                  ....*....|....*....|
gi 6680363    341 IIAKKYDEADYYFQKELSKD 360
Cdd:TIGR02917 510 IQEGNPDDAIQRFEKVLTID 529
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 151-357 1.98e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.39  E-value: 1.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363    151 KNQNERVKVCFQKALEKDPKNpeFTSGWAIANY-----RLDDwparnyCIDSLEQAIQLSPDNtyVKVLLAL-KLDAVHK 224
Cdd:TIGR02917 478 KGDLAKAREAFEKALSIEPDF--FPAAANLARIdiqegNPDD------AIQRFEKVLTIDPKN--LRAILALaGLYLRTG 547

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363    225 NQAMAL--VEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNayVHYYMgccyrskvhhMLNRREMVfS 302
Cdd:TIGR02917 548 NEEEAVawLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDS--PEAWL----------MLGRAQLA-A 614

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 6680363    303 GDRKKleeliqlAVNHLRKAEEIKEMLEYSCSFLADLYIIAKKYDEADYYFQKEL 357
Cdd:TIGR02917 615 GDLNK-------AVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRAL 662
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 151-239 2.96e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.18  E-value: 2.96e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  151 KNQNERVKVCFQKALEKDPKNPEFTSGWAIANYRLDDWPArnyCIDSLEQAIQLSPDNTYVKVLLALKLDAV-HKNQAMA 229
Cdd:COG5010  67 LGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDE---AKEYYEKALALSPDNPNAYSNLAALLLSLgQDDEAKA 143

                        90
                ....*....|
gi 6680363  230 LVEEALKKDP 239
Cdd:COG5010 144 ALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
195-274 3.77e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.46  E-value: 3.77e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  195 IDSLEQAIQLSPDNTYVKVLLALKLDAVHKNQAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPN 274
Cdd:COG3063  12 EEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPS 91
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
226-289 3.96e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.46  E-value: 3.96e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6680363  226 QAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQlLRKALEKLPNNAYVHYYMGCCYRSK 289
Cdd:COG3063  10 EAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLEL 72
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 64-200 4.83e-05

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 45.75  E-value: 4.83e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363   64 RGLNEAALQCLGEAEgfiqQQHPDQVEIrslvtWGNYAWVYYHMGQFSKAQAYLDKVKQVCKKFSSPYRienpaldceeG 143
Cdd:COG3914 125 LGRLEEALAALRRAL----ALNPDFAEA-----YLNLGEALRRLGRLEEAIAALRRALELDPDNAEALN----------N 185

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 6680363  144 WARLKCTKNQNERVKVCFQKALEKDPKNPEFTSGWAIANYRLDDWPARNYCIDSLEQ 200
Cdd:COG3914 186 LGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAA 242
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 213-360 5.34e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.41  E-value: 5.34e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  213 VLLALKLDAVHKNQAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVHYYMGCCYRSkvhh 292
Cdd:COG5010  25 EKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSR---- 100

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6680363  293 mlnrremvfSGDRKKleeliqlAVNHLRKAEEIKEMLEYSCSFLADLYIIAKKYDEADYYFQKELSKD 360
Cdd:COG5010 101 ---------SGDKDE-------AKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
HemYx COG3898
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to HemY-type ...
 162-349 7.66e-05

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to HemY-type protoporphyrinogen oxidase) [Function unknown];


Pssm-ID: 443105 [Multi-domain]  Cd Length: 468  Bit Score: 44.88  E-value: 7.66e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  162 QKALEKDPKNPEftSGWAIANYRLD--DWPARNYCIDSLEQAIQLSPDNtyVK----VLL---ALKLDAVHKNQAMALVE 232
Cdd:COG3898 176 EEALALAPKLPW--AQDALLELQAAagDWDGALATLDAALKAGLLDKDV--ARrrraVLLtarARELEEGDPDEARELAI 251

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  233 EALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPN----NAYVHyymgccyrskvhhmlnrremVFSGD---- 304
Cdd:COG3898 252 EALKLAPDLVPAAVLAARLLIAQGKLRKAAKVLEKAWRAQPHpdlaAAYAE--------------------LRPGDsald 311

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*.
gi 6680363  305 R-KKLEELIQLAVNHLRKAeeikeMLeyscsfLADLYIIAKKYDEA 349
Cdd:COG3898 312 RlKRAETLAALNPDHPESR-----LA------LAEAALAAGDFGEA 346
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 161-279 9.13e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.07  E-value: 9.13e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363    161 FQKALEKDPKNPEFTsGWAIAnyRLDDWPArnyCIDSLEQAIQLSPDNTYVKVLLALKLDAVHKNQAMALVEEALKKDPS 240
Cdd:TIGR02917 695 LQKQHPKAALGFELE-GDLYL--RQKDYPA---AIQAYRKALKRAPSSQNAIKLHRALLASGNTAEAVKTLEAWLKTHPN 768

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 6680363    241 AIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVH 279
Cdd:TIGR02917 769 DAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVL 807
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
257-360 9.91e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 41.31  E-value: 9.91e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  257 DTDRAIQLLRKALEKLPNNAYVHYYMGCCYRskvhhmlnrremvfsgDRKKLEELIQlavnhLRKAEEIKEMLEYSCSFL 336
Cdd:COG3063   7 DLEEAEEYYEKALELDPDNADALNNLGLLLL----------------EQGRYDEAIA-----LEKALKLDPNNAEALLNL 65

                        90       100
                ....*....|....*....|....
gi 6680363  337 ADLYIIAKKYDEADYYFQKELSKD 360
Cdd:COG3063  66 AELLLELGDYDEALAYLERALELD 89
TPR_19 pfam14559
Tetratricopeptide repeat;
225-279 1.45e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 39.87  E-value: 1.45e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 6680363    225 NQAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVH 279
Cdd:pfam14559   5 AEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYA 59
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
151-243 2.58e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.15  E-value: 2.58e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  151 KNQNERVKVCFQKALEKDPKNPEFTSGWAIANYRLDDWP-ARNYcidslEQAIQLSPDNTYVKVLLA-LKLDAVHKNQAM 228
Cdd:COG3063   5 LGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDeAIAL-----EKALKLDPNNAEALLNLAeLLLELGDYDEAL 79

                        90
                ....*....|....*
gi 6680363  229 ALVEEALKKDPSAID 243
Cdd:COG3063  80 AYLERALELDPSALR 94
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 195-273 2.71e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.48  E-value: 2.71e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  195 IDSLEQAIQLSPDNTYVKVLLALKLDAV-HKNQAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLP 273
Cdd:COG5010  74 LALLEQALQLDPNNPELYYNLALLYSRSgDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 198-288 2.77e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.53  E-value: 2.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363    198 LEQAIQLSPDNtyVKVL-----LALKLDAvhkNQAMALVEEALK---KDPSAIDTLlraARFYCKVYDTDRAIQLLRKAL 269
Cdd:TIGR02917 793 YQTVVKKAPDN--AVVLnnlawLYLELKD---PRALEYAERALKlapNIPAILDTL---GWLLVEKGEADRALPLLRKAV 864

                          90
                  ....*....|....*....
gi 6680363    270 EKLPNNAYVHYYMGCCYRS 288
Cdd:TIGR02917 865 NIAPEAAAIRYHLALALLA 883
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 57-208 2.93e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.95  E-value: 2.93e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363   57 LAYVKHCRGLNEAALQCLGEAegfiQQQHPDQVEIrslvtWGNYAWVYYHMGQFSKAQAYLDKVKQVckkfsSPyriENP 136
Cdd:COG4783  10 LAQALLLAGDYDEAEALLEKA----LELDPDNPEA-----FALLGEILLQLGDLDEAIVLLHEALEL-----DP---DEP 72

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6680363  137 ALDCEEGWARLKctKNQNERVKVCFQKALEKDPKNPEFTSGWAIANYRLDDWPARnycIDSLEQAIQLSPDN 208
Cdd:COG4783  73 EARLNLGLALLK--AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEA---IAALEKALELDPDD 139
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 196-432 1.05e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.61  E-value: 1.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363    196 DSLEQAIQLSPDNTYVK-----VLLALKLDAV----HKNQAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLR 266
Cdd:TIGR02917 104 GKFQQVLDELPGKTLLDdegaaELLALRGLAYlglgQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALID 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363    267 KALEKLPNNAYVHYYMGCCYRSK--------------------VHHMLNR-----REMVFSGDRKKLEELIQLAVNHLrK 321
Cdd:TIGR02917 184 EVLTADPGNVDALLLKGDLLLSLgnielalaayrkaialrpnnIAVLLALatiliEAGEFEEAEKHADALLKKAPNSP-L 262

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363    322 AEEIKEMLEYScsfladlyiiAKKYDEADYYFQKELSKDlppgPKQLLHLRYGNFQFFQMKRQDKAIYHYMEGVKIKKKT 401
Cdd:TIGR02917 263 AHYLKALVDFQ----------KKNYEDARETLQDALKSA----PEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNS 328

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 6680363    402 IPQKKM------REKLQRIALRRLH----EDESDSEALHIL 432
Cdd:TIGR02917 329 HQARRLlasiqlRLGRVDEAIATLSpalgLDPDDPAALSLL 369
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 155-288 2.23e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.92  E-value: 2.23e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  155 ERVKVCFQKALEKDPKNPEFTSgwAIANYRLddwparnyCIDSLEQAIQlspdntYVKVLLALKLDAVHKNQAMALVEEA 234
Cdd:cd24142 143 QRCEELITKALELDPTNPEALQ--TLASLRI--------SQQRPDEAKE------ALRRSLELWKDLKEEDEEEAEEDEA 206

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 6680363  235 LKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVHYYMGCCYRS 288
Cdd:cd24142 207 EEEDVPSYEFRISLAKLLIELEMYEEALEVLEQLLDEDDEDVEVWYLLGWAYYL 260
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 226-340 2.39e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.92  E-value: 2.39e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  226 QAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVHY-YMG---------CCYRSKVHHMln 295
Cdd:cd24142  18 LALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYEKYlYLGqlsggeealQYYEKGIEIL-- 95

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*
gi 6680363  296 rremvfsgdRKKLEELIQLAVNHLRKAEEIKEMLEYSCSFLADLY 340
Cdd:cd24142  96 ---------EEELQALQAASAEAEEEAEELKRKLSSALCALAEIY 131
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 152-276 3.50e-03

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 38.86  E-value: 3.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363    152 NQNERVKVCFQKALEKDPKNPEFTSGWAIANYRL--DDWPARNYcidslEQAIQLSPD-----NTYVKVLLALKldavHK 224
Cdd:TIGR02521  45 GDLEVAKENLDKALEHDPDDYLAYLALALYYQQLgeLEKAEDSF-----RRALTLNPNngdvlNNYGTFLCQQG----KY 115

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 6680363    225 NQAMALVEEALK--KDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNA 276
Cdd:TIGR02521 116 EQAMQQFEQAIEdpLYPQPARSLENAGLCALKAGDFDKAEKYLTRALQIDPQRP 169
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
161-277 5.42e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 38.36  E-value: 5.42e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  161 FQKALEKDPKNPEFTSGWAIANYRLDDWPArnyCIDSLEQAIQLSPDNTYvkvllalkldaVHKNQAMALveEALKKDPS 240
Cdd:COG4785  96 FDQALELDPDLAEAYNNRGLAYLLLGDYDA---ALEDFDRALELDPDYAY-----------AYLNRGIAL--YYLGRYEL 159

                        90       100       110
                ....*....|....*....|....*....|....*..
gi 6680363  241 AIDTLLRAARFYCKvyDTDRAIQLLRKALEKLPNNAY 277
Cdd:COG4785 160 AIADLEKALELDPN--DPERALWLYLAERKLDPEKAL 194
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
55-272 6.04e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 38.45  E-value: 6.04e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363   55 NILAYVKHCRGLNEAALQCLGEAEgfiqQQHPDQVEIrslvtWGNYAWVYYHMGQFSKAQAYLDKVKQVCKKFSSPYRie 134
Cdd:COG0457  46 YNLGLAYLRLGRYEEALADYEQAL----ELDPDDAEA-----LNNLGLALQALGRYEEALEDYDKALELDPDDAEALY-- 114

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  135 npaldceeGWARLKCTKNQNERVKVCFQKALEKDPKNPEFTSGWAIANYRLDDWPARNYCIDSLEQAIQLSPDNTYVKVL 214
Cdd:COG0457 115 --------NLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEA 186

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 6680363  215 LALKLDAVHKNQAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKL 272
Cdd:COG0457 187 ALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYR 244
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 198-283 6.78e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 38.35  E-value: 6.78e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  198 LEQAIQLSPDNTYVKVLLALKLDAVHKnqAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPnNAY 277
Cdd:COG3071 216 LREALKRQWDPRLVRLYGRLQGGDPAK--QLKRAEKWLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEAALALRP-SAE 292


                ....*.
gi 6680363  278 VHYYMG 283
Cdd:COG3071 293 AYAELA 298
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
161-270 6.80e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 37.97  E-value: 6.80e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680363  161 FQKALEKDPKNPEFTSGWAIANYRLDDWPArnyCIDSLEQAIQLSPDNTYVKVLLALKLDAVHKNQAMALVEEALKKDPS 240
Cdd:COG4785 130 FDRALELDPDYAYAYLNRGIALYYLGRYEL---AIADLEKALELDPNDPERALWLYLAERKLDPEKALALLLEDWATAYL 206

                        90       100       110
                ....*....|....*....|....*....|
gi 6680363  241 AIDtllraarfyckvyDTDRAIQLLRKALE 270
Cdd:COG4785 207 LQG-------------DTEEARELFKLALA 223
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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