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Conserved domains on  [gi|40288197|ref|NP_005248|]
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transcription factor GATA-6 [Homo sapiens]

Protein Classification

GATA-type transcription factor( domain architecture ID 13711596)

GATA-type transcription factor binds to the DNA consensus sequence [AT]GATA[AG] and may function as a transcription factor/regulator

CATH:  3.30.50.10
Gene Ontology:  GO:0003700|GO:0006357|GO:0006355|GO:0008270|GO:0043565|GO:0000981
PubMed:  31574210
SCOP:  4003617

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GATA-N pfam05349
GATA-type transcription activator, N-terminal; GATA transcription factors mediate cell ...
 147-377 4.34e-44

GATA-type transcription activator, N-terminal; GATA transcription factors mediate cell differentiation in a diverse range of tissues. Mutation are often associated with certain congenital human disorders. The six classical vertebrate GATA proteins, GATA-1 to GATA-6, are highly homologous and have two tandem zinc fingers. The classical GATA transcription factors function transcription activators. In lower metazoans GATA proteins carry a single canonical zinc finger. This family represents the N-terminal domain of the family of GATA transcription activators.


:

Pssm-ID: 461628 [Multi-domain]  Cd Length: 174  Bit Score: 154.90  E-value: 4.34e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40288197   147 MYQTLAALSSQGPAAYDGAPGGFVHSAAAAaaaaaaassPVYVPTTRVGSMLPGLPYhLQGSGSGPANHAGGAgaHPGWP 226
Cdd:pfam05349   1 MYQSLALAANHGQAAYDHDSGGFLHSAASS---------PVYVPTTRVPSMLPTLPY-LQGCGSSQQSHPVSS--HSGWA 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40288197   227 QASADSPPYGSGGGaagggaagpggagsaaaHVSARFPYSPSPPMANGAAREpggyaaagsggaggVSGGGSSLAAMGGR 306
Cdd:pfam05349  69 QAGAESSSYNPGSP-----------------HPSPRFSYSHSPPGSNGTSRD--------------AAYQSPLLISAGGR 117

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 40288197   307 EpQYSSLsaARPLNGTYhhhhhhhhhhPSPYSPYVGAPLTPAWPAGPFETPVLHSLQSRaGAPLPVpRGPS 377
Cdd:pfam05349 118 E-QYGAL--GRPLGGSY----------PSPYPAYVSPEMAPSWTAGPFDSSVLHSLQGR-GAPLPG-RRPN 173
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 443-494 5.41e-21

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


:

Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 86.27  E-value: 5.41e-21
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 40288197 443 SCANCHTTTTTLWRRN-AEGEPVCNACGLYMKLHGVPRPLAMKKEG-IQTRKRK 494
Cdd:cd00202   1 ACSNCGTTTTPLWRRGpSGGSTLCNACGLYWKKHGVMRPLSKRKKDqIKRRNRK 54
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 389-434 1.16e-17

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


:

Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 77.03  E-value: 1.16e-17
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*..
gi 40288197 389 ECVNCGSIQTPLWRRDG-TGHYLCNACGLYSKMNGLSRPLIKPQKRV 434
Cdd:cd00202   1 ACSNCGTTTTPLWRRGPsGGSTLCNACGLYWKKHGVMRPLSKRKKDQ 47
GAT1 super family cl35034
GATA Zn-finger-containing transcription factor [Transcription];
373-591 4.31e-07

GATA Zn-finger-containing transcription factor [Transcription];


The actual alignment was detected with superfamily member COG5641:

Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 52.57  E-value: 4.31e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40288197 373 PRGPSADLLEDLSESRECVNCGSIQTPLWRRD-----GTGHYLCNACGLYSKMNGLSRPLIKPQKRVPSSRRLGLSCANC 447
Cdd:COG5641 144 SLNPNNNQSDNSNQPHVCSNCKTTSTPLWRRAssessLPGNNLCNACGLYLKLHGSPRAPISLKSDSIKSRSSRSSHNNN 223

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40288197 448 -HTTTTTLWRRNAEGEPVCNACGLYMKLHGvpRPLAMKKEGIQTRKRKPKNINKSKTCSGNSNNSIPMTPTSTSSNSDDC 526
Cdd:COG5641 224 dSNGENANTESIGNSSASKLTKSWEERPQG--RQLLSDAGSLSPRSNNPKSPLLEGLMGSTSLQPVSTPKLVLPSDKKRS 301

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 40288197 527 SKNTSPTTQPTASGAGApvmtgAGESTNPENSELKysgqdgLYIGVSLASPAEVTSSVRPDSWCA 591
Cdd:COG5641 302 TLTTSTATPLWRRTSDK-----SSFSCNASGSALK------PPGSKRPLLPKPDPNSKRSNATCM 355
 
Name Accession Description Interval E-value
GATA-N pfam05349
GATA-type transcription activator, N-terminal; GATA transcription factors mediate cell ...
 147-377 4.34e-44

GATA-type transcription activator, N-terminal; GATA transcription factors mediate cell differentiation in a diverse range of tissues. Mutation are often associated with certain congenital human disorders. The six classical vertebrate GATA proteins, GATA-1 to GATA-6, are highly homologous and have two tandem zinc fingers. The classical GATA transcription factors function transcription activators. In lower metazoans GATA proteins carry a single canonical zinc finger. This family represents the N-terminal domain of the family of GATA transcription activators.


Pssm-ID: 461628 [Multi-domain]  Cd Length: 174  Bit Score: 154.90  E-value: 4.34e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40288197   147 MYQTLAALSSQGPAAYDGAPGGFVHSAAAAaaaaaaassPVYVPTTRVGSMLPGLPYhLQGSGSGPANHAGGAgaHPGWP 226
Cdd:pfam05349   1 MYQSLALAANHGQAAYDHDSGGFLHSAASS---------PVYVPTTRVPSMLPTLPY-LQGCGSSQQSHPVSS--HSGWA 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40288197   227 QASADSPPYGSGGGaagggaagpggagsaaaHVSARFPYSPSPPMANGAAREpggyaaagsggaggVSGGGSSLAAMGGR 306
Cdd:pfam05349  69 QAGAESSSYNPGSP-----------------HPSPRFSYSHSPPGSNGTSRD--------------AAYQSPLLISAGGR 117

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 40288197   307 EpQYSSLsaARPLNGTYhhhhhhhhhhPSPYSPYVGAPLTPAWPAGPFETPVLHSLQSRaGAPLPVpRGPS 377
Cdd:pfam05349 118 E-QYGAL--GRPLGGSY----------PSPYPAYVSPEMAPSWTAGPFDSSVLHSLQGR-GAPLPG-RRPN 173
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 443-494 5.41e-21

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 86.27  E-value: 5.41e-21
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 40288197 443 SCANCHTTTTTLWRRN-AEGEPVCNACGLYMKLHGVPRPLAMKKEG-IQTRKRK 494
Cdd:cd00202   1 ACSNCGTTTTPLWRRGpSGGSTLCNACGLYWKKHGVMRPLSKRKKDqIKRRNRK 54
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
441-488 1.10e-17

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 77.07  E-value: 1.10e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 40288197    441 GLSCANCHTTTTTLWRRNAEGE-PVCNACGLYMKLHGVP-RPLAMKKEGI 488
Cdd:smart00401   3 GRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHGGLkRPLSLKKDGI 52
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 389-434 1.16e-17

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 77.03  E-value: 1.16e-17
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*..
gi 40288197 389 ECVNCGSIQTPLWRRDG-TGHYLCNACGLYSKMNGLSRPLIKPQKRV 434
Cdd:cd00202   1 ACSNCGTTTTPLWRRGPsGGSTLCNACGLYWKKHGVMRPLSKRKKDQ 47
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 444-478 3.85e-14

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 66.57  E-value: 3.85e-14
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 40288197   444 CANCHTTTTTLWRRNAEGEP-VCNACGLYMKLHGVP 478
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGLK 36
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
388-435 3.77e-13

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 63.98  E-value: 3.77e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 40288197    388 RECVNCGSIQTPLWRRDGTGH-YLCNACGLYSKMNGLSRPLIKPQKRVP 435
Cdd:smart00401   4 RSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHGGLKRPLSLKKDGI 52
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 390-423 3.98e-12

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 60.79  E-value: 3.98e-12
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 40288197   390 CVNCGSIQTPLWRRDGTGHY-LCNACGLYSKMNGL 423
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGL 35
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
443-533 2.50e-10

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 62.97  E-value: 2.50e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40288197 443 SCANCHTTTTTLWRR-----NAEGEPVCNACGLYMKLHGVPR-PLAMKKEGIQTR-KRKPKNINKSKTCSGNSnNSIPMT 515
Cdd:COG5641 160 VCSNCKTTSTPLWRRassesSLPGNNLCNACGLYLKLHGSPRaPISLKSDSIKSRsSRSSHNNNDSNGENANT-ESIGNS 238

                        90
                ....*....|....*...
gi 40288197 516 PTSTSSNSDDCSKNTSPT 533
Cdd:COG5641 239 SASKLTKSWEERPQGRQL 256
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
364-528 7.90e-09

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 58.34  E-value: 7.90e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40288197 364 SRAGAPLPVPRgpsADLLEDLSESRecvNCGSIQTPLWRR-DGTGHYLCNACGLYSKMNGLSRPLikPQKRVPSSRRLGL 442
Cdd:COG5641 281 STSLQPVSTPK---LVLPSDKKRST---LTTSTATPLWRRtSDKSSFSCNASGSALKPPGSKRPL--LPKPDPNSKRSNA 352

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40288197 443 SCANCHTTTTTLWRrnaEGEPVCNACGLYMKLHGVPRPLAMKKEGIQTRKRKPKNINKSKTCSGNSNNSI--PMTPTSTS 520
Cdd:COG5641 353 TCMNCSSTPTNKIL---SPPTTSNSPGAQVKLPNQTRSTGATKKKITRRRMNSGKIPALSSSMKNPVPKEfsPLIPQSTE 429


                ....*...
gi 40288197 521 SNSDDCSK 528
Cdd:COG5641 430 SETPSQSK 437
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
373-591 4.31e-07

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 52.57  E-value: 4.31e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40288197 373 PRGPSADLLEDLSESRECVNCGSIQTPLWRRD-----GTGHYLCNACGLYSKMNGLSRPLIKPQKRVPSSRRLGLSCANC 447
Cdd:COG5641 144 SLNPNNNQSDNSNQPHVCSNCKTTSTPLWRRAssessLPGNNLCNACGLYLKLHGSPRAPISLKSDSIKSRSSRSSHNNN 223

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40288197 448 -HTTTTTLWRRNAEGEPVCNACGLYMKLHGvpRPLAMKKEGIQTRKRKPKNINKSKTCSGNSNNSIPMTPTSTSSNSDDC 526
Cdd:COG5641 224 dSNGENANTESIGNSSASKLTKSWEERPQG--RQLLSDAGSLSPRSNNPKSPLLEGLMGSTSLQPVSTPKLVLPSDKKRS 301

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 40288197 527 SKNTSPTTQPTASGAGApvmtgAGESTNPENSELKysgqdgLYIGVSLASPAEVTSSVRPDSWCA 591
Cdd:COG5641 302 TLTTSTATPLWRRTSDK-----SSFSCNASGSALK------PPGSKRPLLPKPDPNSKRSNATCM 355
 
Name Accession Description Interval E-value
GATA-N pfam05349
GATA-type transcription activator, N-terminal; GATA transcription factors mediate cell ...
 147-377 4.34e-44

GATA-type transcription activator, N-terminal; GATA transcription factors mediate cell differentiation in a diverse range of tissues. Mutation are often associated with certain congenital human disorders. The six classical vertebrate GATA proteins, GATA-1 to GATA-6, are highly homologous and have two tandem zinc fingers. The classical GATA transcription factors function transcription activators. In lower metazoans GATA proteins carry a single canonical zinc finger. This family represents the N-terminal domain of the family of GATA transcription activators.


Pssm-ID: 461628 [Multi-domain]  Cd Length: 174  Bit Score: 154.90  E-value: 4.34e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40288197   147 MYQTLAALSSQGPAAYDGAPGGFVHSAAAAaaaaaaassPVYVPTTRVGSMLPGLPYhLQGSGSGPANHAGGAgaHPGWP 226
Cdd:pfam05349   1 MYQSLALAANHGQAAYDHDSGGFLHSAASS---------PVYVPTTRVPSMLPTLPY-LQGCGSSQQSHPVSS--HSGWA 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40288197   227 QASADSPPYGSGGGaagggaagpggagsaaaHVSARFPYSPSPPMANGAAREpggyaaagsggaggVSGGGSSLAAMGGR 306
Cdd:pfam05349  69 QAGAESSSYNPGSP-----------------HPSPRFSYSHSPPGSNGTSRD--------------AAYQSPLLISAGGR 117

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 40288197   307 EpQYSSLsaARPLNGTYhhhhhhhhhhPSPYSPYVGAPLTPAWPAGPFETPVLHSLQSRaGAPLPVpRGPS 377
Cdd:pfam05349 118 E-QYGAL--GRPLGGSY----------PSPYPAYVSPEMAPSWTAGPFDSSVLHSLQGR-GAPLPG-RRPN 173
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 443-494 5.41e-21

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 86.27  E-value: 5.41e-21
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 40288197 443 SCANCHTTTTTLWRRN-AEGEPVCNACGLYMKLHGVPRPLAMKKEG-IQTRKRK 494
Cdd:cd00202   1 ACSNCGTTTTPLWRRGpSGGSTLCNACGLYWKKHGVMRPLSKRKKDqIKRRNRK 54
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
441-488 1.10e-17

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 77.07  E-value: 1.10e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 40288197    441 GLSCANCHTTTTTLWRRNAEGE-PVCNACGLYMKLHGVP-RPLAMKKEGI 488
Cdd:smart00401   3 GRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHGGLkRPLSLKKDGI 52
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 389-434 1.16e-17

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 77.03  E-value: 1.16e-17
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*..
gi 40288197 389 ECVNCGSIQTPLWRRDG-TGHYLCNACGLYSKMNGLSRPLIKPQKRV 434
Cdd:cd00202   1 ACSNCGTTTTPLWRRGPsGGSTLCNACGLYWKKHGVMRPLSKRKKDQ 47
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 444-478 3.85e-14

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 66.57  E-value: 3.85e-14
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 40288197   444 CANCHTTTTTLWRRNAEGEP-VCNACGLYMKLHGVP 478
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGLK 36
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
388-435 3.77e-13

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 63.98  E-value: 3.77e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 40288197    388 RECVNCGSIQTPLWRRDGTGH-YLCNACGLYSKMNGLSRPLIKPQKRVP 435
Cdd:smart00401   4 RSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHGGLKRPLSLKKDGI 52
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 390-423 3.98e-12

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 60.79  E-value: 3.98e-12
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 40288197   390 CVNCGSIQTPLWRRDGTGHY-LCNACGLYSKMNGL 423
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGL 35
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
443-533 2.50e-10

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 62.97  E-value: 2.50e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40288197 443 SCANCHTTTTTLWRR-----NAEGEPVCNACGLYMKLHGVPR-PLAMKKEGIQTR-KRKPKNINKSKTCSGNSnNSIPMT 515
Cdd:COG5641 160 VCSNCKTTSTPLWRRassesSLPGNNLCNACGLYLKLHGSPRaPISLKSDSIKSRsSRSSHNNNDSNGENANT-ESIGNS 238

                        90
                ....*....|....*...
gi 40288197 516 PTSTSSNSDDCSKNTSPT 533
Cdd:COG5641 239 SASKLTKSWEERPQGRQL 256
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
364-528 7.90e-09

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 58.34  E-value: 7.90e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40288197 364 SRAGAPLPVPRgpsADLLEDLSESRecvNCGSIQTPLWRR-DGTGHYLCNACGLYSKMNGLSRPLikPQKRVPSSRRLGL 442
Cdd:COG5641 281 STSLQPVSTPK---LVLPSDKKRST---LTTSTATPLWRRtSDKSSFSCNASGSALKPPGSKRPL--LPKPDPNSKRSNA 352

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40288197 443 SCANCHTTTTTLWRrnaEGEPVCNACGLYMKLHGVPRPLAMKKEGIQTRKRKPKNINKSKTCSGNSNNSI--PMTPTSTS 520
Cdd:COG5641 353 TCMNCSSTPTNKIL---SPPTTSNSPGAQVKLPNQTRSTGATKKKITRRRMNSGKIPALSSSMKNPVPKEfsPLIPQSTE 429


                ....*...
gi 40288197 521 SNSDDCSK 528
Cdd:COG5641 430 SETPSQSK 437
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
373-591 4.31e-07

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 52.57  E-value: 4.31e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40288197 373 PRGPSADLLEDLSESRECVNCGSIQTPLWRRD-----GTGHYLCNACGLYSKMNGLSRPLIKPQKRVPSSRRLGLSCANC 447
Cdd:COG5641 144 SLNPNNNQSDNSNQPHVCSNCKTTSTPLWRRAssessLPGNNLCNACGLYLKLHGSPRAPISLKSDSIKSRSSRSSHNNN 223

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40288197 448 -HTTTTTLWRRNAEGEPVCNACGLYMKLHGvpRPLAMKKEGIQTRKRKPKNINKSKTCSGNSNNSIPMTPTSTSSNSDDC 526
Cdd:COG5641 224 dSNGENANTESIGNSSASKLTKSWEERPQG--RQLLSDAGSLSPRSNNPKSPLLEGLMGSTSLQPVSTPKLVLPSDKKRS 301

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 40288197 527 SKNTSPTTQPTASGAGApvmtgAGESTNPENSELKysgqdgLYIGVSLASPAEVTSSVRPDSWCA 591
Cdd:COG5641 302 TLTTSTATPLWRRTSDK-----SSFSCNASGSALK------PPGSKRPLLPKPDPNSKRSNATCM 355
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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