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Conserved domains on  [gi|1919629425|ref|NP_001375293|]
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seizure 6-like protein 2 isoform 8 precursor [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 527-617 1.09e-19

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


:

Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 85.16  E-value: 1.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 527 CGGELSEPA-GVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-----DMLTLFDGDGPSARVLAQLRGPQ 600
Cdd:cd00041     1 CGGTLTASTsGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsyDYLEIYDGPSTSSPLLGRFCGST 80

                          90
                  ....*....|....*..
gi 1919629425 601 PRRRLLSSGPDLTLQFQ 617
Cdd:cd00041    81 LPPPIISSGNSLTVRFR 97
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 349-417 1.80e-15

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


:

Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 73.22  E-value: 1.80e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1919629425 349 CGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDED----NDRLMVRSGGSPLSPVI 417
Cdd:cd00041     1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsYDYLEIYDGPSTSSPLL 73
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 644-700 2.57e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 62.48  E-value: 2.57e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1919629425 644 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQ 700
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 173-285 3.88e-12

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


:

Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 63.59  E-value: 3.88e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 173 CNNNIS-EGEGYVESPDLGSPVSRtlgLLDCTYSIHVYPGYGIEIQVQTLNLSQEEE-----LLVLAGGGSpglaprlla 246
Cdd:cd00041     1 CGGTLTaSTSGTISSPNYPNNYPN---NLNCVWTIEAPPGYRIRLTFEDFDLESSPNcsydyLEIYDGPST--------- 68

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1919629425 247 NSSMLGE------GQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQA 285
Cdd:cd00041    69 SSPLLGRfcgstlPPPIISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 705-764 4.33e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


:

Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 58.69  E-value: 4.33e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425  705 CADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCysrdTGTPKWSDRVPKC 764
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITC----LENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 290-345 1.44e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


:

Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 57.15  E-value: 1.44e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1919629425  290 CGFPPRPAHGDVSV--TDLHPGGTATFHCDSGYQLQGEETLICLNGTrpSWNGETPSC 345
Cdd:smart00032   1 CPPPPDIENGTVTSssGTYSYGDTVTYSCDPGYTLIGSSTITCLENG--TWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
464-523 1.18e-06

Sushi repeat (SCR repeat);


:

Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 46.34  E-value: 1.18e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1919629425 464 CFAPF-LAHGNVTTTDPEYRPGALATFSCLPGYALEppgPPNAIECVDptEPHWNDTEPAC 523
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRLV---GSPTITCQE--DGTWSPPFPEC 56
 
Name Accession Description Interval E-value
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 527-617 1.09e-19

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 85.16  E-value: 1.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 527 CGGELSEPA-GVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-----DMLTLFDGDGPSARVLAQLRGPQ 600
Cdd:cd00041     1 CGGTLTASTsGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsyDYLEIYDGPSTSSPLLGRFCGST 80

                          90
                  ....*....|....*..
gi 1919629425 601 PRRRLLSSGPDLTLQFQ 617
Cdd:cd00041    81 LPPPIISSGNSLTVRFR 97
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 349-417 1.80e-15

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 73.22  E-value: 1.80e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1919629425 349 CGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDED----NDRLMVRSGGSPLSPVI 417
Cdd:cd00041     1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsYDYLEIYDGPSTSSPLL 73
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 644-700 2.57e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 62.48  E-value: 2.57e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1919629425 644 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQ 700
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 173-285 3.88e-12

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 63.59  E-value: 3.88e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 173 CNNNIS-EGEGYVESPDLGSPVSRtlgLLDCTYSIHVYPGYGIEIQVQTLNLSQEEE-----LLVLAGGGSpglaprlla 246
Cdd:cd00041     1 CGGTLTaSTSGTISSPNYPNNYPN---NLNCVWTIEAPPGYRIRLTFEDFDLESSPNcsydyLEIYDGPST--------- 68

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1919629425 247 NSSMLGE------GQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQA 285
Cdd:cd00041    69 SSPLLGRfcgstlPPPIISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 644-699 8.06e-12

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 61.00  E-value: 8.06e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1919629425  644 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPAC 699
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CUB pfam00431
CUB domain;
527-617 8.88e-12

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 62.31  E-value: 8.88e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 527 CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVRE-----GDMLTLFDGDGPSARVLAQLRGPQP 601
Cdd:pfam00431   1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDhdecgYDYVEIRDGPSASSPLLGRFCGSGI 80

                          90
                  ....*....|....*.
gi 1919629425 602 RRRLLSSGPDLTLQFQ 617
Cdd:pfam00431  81 PEDIVSSSNQMTIKFV 96
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 536-617 2.25e-11

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 61.25  E-value: 2.25e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425  536 GVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-----DMLTLFDGDGPSARVLAQLRGPQ-PRRRLLSSG 609
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSdnceyDYVEIYDGPSASSPLLGRFCGSEaPPPVISSSS 80


                   ....*...
gi 1919629425  610 PDLTLQFQ 617
Cdd:smart00042  81 NSLTLTFV 88
Sushi pfam00084
Sushi repeat (SCR repeat);
644-699 4.04e-11

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 59.05  E-value: 4.04e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1919629425 644 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPAC 699
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 705-764 4.33e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 58.69  E-value: 4.33e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425  705 CADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCysrdTGTPKWSDRVPKC 764
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITC----LENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 705-764 5.54e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 58.63  E-value: 5.54e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 705 CADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCysrdTGTPKWSDRVPKC 764
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITC----TENGGWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 290-345 1.44e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 57.15  E-value: 1.44e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1919629425  290 CGFPPRPAHGDVSV--TDLHPGGTATFHCDSGYQLQGEETLICLNGTrpSWNGETPSC 345
Cdd:smart00032   1 CPPPPDIENGTVTSssGTYSYGDTVTYSCDPGYTLIGSSTITCLENG--TWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 290-345 2.62e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 56.70  E-value: 2.62e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1919629425 290 CGFPPRPAHGDV--SVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTrpsWNGETPSC 345
Cdd:cd00033     1 CPPPPVPENGTVtgSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGG---WSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 644-764 2.68e-10

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 61.98  E-value: 2.68e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 644 CPeLPPPEWGWRTASHGDL-IRGTVLTYQCEPGYELLGSDILTCQWDlSWSAaPPACQkIMTCADPgEIANGHRTAS-DA 721
Cdd:PHA02927  148 CQ-SPPSISNGRHNGYEDFyTDGSVVTYSCNSGYSLIGNSGVLCSGG-EWSD-PPTCQ-IVKCPHP-TISNGYLSSGfKR 222

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1919629425 722 GFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTgtpkWSDRVPKC 764
Cdd:PHA02927  223 SYSYNDNVDFKCKYGYKLSGSSSSTCSPGNT----WQPELPKC 261
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 665-764 7.93e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 57.36  E-value: 7.93e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 665 GTVLTYQCEPGYELLGSDILTCQW----DLSWSAAPPACQKImTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLE 740
Cdd:PHA02927  105 GSSITYSCNSGYQLIGESKSYCELgstgSMVWNPEAPICESV-KCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLI 183

                          90       100
                  ....*....|....*....|....
gi 1919629425 741 GAAMLTCYSRDtgtpkWSDRvPKC 764
Cdd:PHA02927  184 GNSGVLCSGGE-----WSDP-PTC 201
Sushi pfam00084
Sushi repeat (SCR repeat);
290-345 8.96e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 52.12  E-value: 8.96e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1919629425 290 CGFPPRPAHGDVSVTD--LHPGGTATFHCDSGYQLQGEETLICLNGtrPSWNGETPSC 345
Cdd:pfam00084   1 CPPPPDIPNGKVSATKneYNYGASVSYECDPGYRLVGSPTITCQED--GTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
705-764 3.85e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 50.58  E-value: 3.85e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 705 CADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCysrdTGTPKWSDRVPKC 764
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITC----QEDGTWSPPFPEC 56
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 359-417 4.46e-08

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 51.62  E-value: 4.46e-08
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1919629425  359 GRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDN----DRLMVRSGGSPLSPVI 417
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSDnceyDYVEIYDGPSASSPLL 63
Sushi pfam00084
Sushi repeat (SCR repeat);
464-523 1.18e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 46.34  E-value: 1.18e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1919629425 464 CFAPF-LAHGNVTTTDPEYRPGALATFSCLPGYALEppgPPNAIECVDptEPHWNDTEPAC 523
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRLV---GSPTITCQE--DGTWSPPFPEC 56
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 182-283 8.83e-06

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 45.07  E-value: 8.83e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425  182 GYVESPDLGSPVSRtlgLLDCTYSIHVYPGYGIEIQVQTLNLSQEEE-----LLVLAGggsPGLAPRLLAN--SSMLGEg 254
Cdd:smart00042   1 GTITSPNYPQSYPN---NLDCVWTIRAPPGYRIELQFTDFDLESSDNceydyVEIYDG---PSASSPLLGRfcGSEAPP- 73

                           90       100
                   ....*....|....*....|....*....
gi 1919629425  255 QVLRSPTNRLLLHFQSPRVPRGGGFRIHY 283
Cdd:smart00042  74 PVISSSSNSLTLTFVSDSSVQKRGFSARY 102
CUB pfam00431
CUB domain;
349-417 4.13e-05

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 43.44  E-value: 4.13e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1919629425 349 CGGTIHNATlGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDED----NDRLMVRSGGSPLSPVI 417
Cdd:pfam00431   1 CGGVLTDSS-GSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHdecgYDYVEIRDGPSASSPLL 72
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 467-524 8.90e-05

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 40.91  E-value: 8.90e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1919629425 467 PFLAHGNVTTTDPEYRPGALATFSCLPGYALEppgPPNAIECVDptEPHWNDTEPACK 524
Cdd:cd00033     5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTLV---GSSTITCTE--NGGWSPPPPTCE 57
CUB pfam00431
CUB domain;
173-283 9.15e-05

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 42.67  E-value: 9.15e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 173 CNNNISEGEGYVESPDLGSPVSRtlgLLDCTYSIHVYPGYGIEIQVQTLNLSQEEE-----LLVLAGGGspglaprllAN 247
Cdd:pfam00431   1 CGGVLTDSSGSISSPNYPNPYPP---NKDCVWLIRAPPGFRVKLTFQDFELEDHDEcgydyVEIRDGPS---------AS 68

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1919629425 248 SSMLGE------GQVLRSPTNRLLLHFQSPRVPRGGGFRIHY 283
Cdd:pfam00431  69 SPLLGRfcgsgiPEDIVSSSNQMTIKFVSDASVQKRGFKATY 110
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 467-523 3.63e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 39.05  E-value: 3.63e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1919629425  467 PFLAHGNVTTTDPEYRPGALATFSCLPGYALEppgPPNAIECVDptEPHWNDTEPAC 523
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTLI---GSSTITCLE--NGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 276-345 1.54e-03

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 41.18  E-value: 1.54e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1919629425 276 GGGFRIHYQAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPS--WNGETPSC 345
Cdd:PHA02927   72 GTGWTLFNQCIKRRCPSPRDIDNGQLDIGGVDFGSSITYSCNSGYQLIGESKSYCELGSTGSmvWNPEAPIC 143
 
Name Accession Description Interval E-value
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 527-617 1.09e-19

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 85.16  E-value: 1.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 527 CGGELSEPA-GVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-----DMLTLFDGDGPSARVLAQLRGPQ 600
Cdd:cd00041     1 CGGTLTASTsGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsyDYLEIYDGPSTSSPLLGRFCGST 80

                          90
                  ....*....|....*..
gi 1919629425 601 PRRRLLSSGPDLTLQFQ 617
Cdd:cd00041    81 LPPPIISSGNSLTVRFR 97
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 349-417 1.80e-15

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 73.22  E-value: 1.80e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1919629425 349 CGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDED----NDRLMVRSGGSPLSPVI 417
Cdd:cd00041     1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsYDYLEIYDGPSTSSPLL 73
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 644-700 2.57e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 62.48  E-value: 2.57e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1919629425 644 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQ 700
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 173-285 3.88e-12

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 63.59  E-value: 3.88e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 173 CNNNIS-EGEGYVESPDLGSPVSRtlgLLDCTYSIHVYPGYGIEIQVQTLNLSQEEE-----LLVLAGGGSpglaprlla 246
Cdd:cd00041     1 CGGTLTaSTSGTISSPNYPNNYPN---NLNCVWTIEAPPGYRIRLTFEDFDLESSPNcsydyLEIYDGPST--------- 68

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1919629425 247 NSSMLGE------GQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQA 285
Cdd:cd00041    69 SSPLLGRfcgstlPPPIISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 644-699 8.06e-12

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 61.00  E-value: 8.06e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1919629425  644 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPAC 699
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CUB pfam00431
CUB domain;
527-617 8.88e-12

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 62.31  E-value: 8.88e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 527 CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVRE-----GDMLTLFDGDGPSARVLAQLRGPQP 601
Cdd:pfam00431   1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDhdecgYDYVEIRDGPSASSPLLGRFCGSGI 80

                          90
                  ....*....|....*.
gi 1919629425 602 RRRLLSSGPDLTLQFQ 617
Cdd:pfam00431  81 PEDIVSSSNQMTIKFV 96
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 536-617 2.25e-11

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 61.25  E-value: 2.25e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425  536 GVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-----DMLTLFDGDGPSARVLAQLRGPQ-PRRRLLSSG 609
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSdnceyDYVEIYDGPSASSPLLGRFCGSEaPPPVISSSS 80


                   ....*...
gi 1919629425  610 PDLTLQFQ 617
Cdd:smart00042  81 NSLTLTFV 88
Sushi pfam00084
Sushi repeat (SCR repeat);
644-699 4.04e-11

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 59.05  E-value: 4.04e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1919629425 644 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPAC 699
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 705-764 4.33e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 58.69  E-value: 4.33e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425  705 CADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCysrdTGTPKWSDRVPKC 764
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITC----LENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 705-764 5.54e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 58.63  E-value: 5.54e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 705 CADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCysrdTGTPKWSDRVPKC 764
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITC----TENGGWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 290-345 1.44e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 57.15  E-value: 1.44e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1919629425  290 CGFPPRPAHGDVSV--TDLHPGGTATFHCDSGYQLQGEETLICLNGTrpSWNGETPSC 345
Cdd:smart00032   1 CPPPPDIENGTVTSssGTYSYGDTVTYSCDPGYTLIGSSTITCLENG--TWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 290-345 2.62e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 56.70  E-value: 2.62e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1919629425 290 CGFPPRPAHGDV--SVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTrpsWNGETPSC 345
Cdd:cd00033     1 CPPPPVPENGTVtgSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGG---WSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 644-764 2.68e-10

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 61.98  E-value: 2.68e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 644 CPeLPPPEWGWRTASHGDL-IRGTVLTYQCEPGYELLGSDILTCQWDlSWSAaPPACQkIMTCADPgEIANGHRTAS-DA 721
Cdd:PHA02927  148 CQ-SPPSISNGRHNGYEDFyTDGSVVTYSCNSGYSLIGNSGVLCSGG-EWSD-PPTCQ-IVKCPHP-TISNGYLSSGfKR 222

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1919629425 722 GFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTgtpkWSDRVPKC 764
Cdd:PHA02927  223 SYSYNDNVDFKCKYGYKLSGSSSSTCSPGNT----WQPELPKC 261
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 665-764 7.93e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 57.36  E-value: 7.93e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 665 GTVLTYQCEPGYELLGSDILTCQW----DLSWSAAPPACQKImTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLE 740
Cdd:PHA02927  105 GSSITYSCNSGYQLIGESKSYCELgstgSMVWNPEAPICESV-KCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLI 183

                          90       100
                  ....*....|....*....|....
gi 1919629425 741 GAAMLTCYSRDtgtpkWSDRvPKC 764
Cdd:PHA02927  184 GNSGVLCSGGE-----WSDP-PTC 201
Sushi pfam00084
Sushi repeat (SCR repeat);
290-345 8.96e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 52.12  E-value: 8.96e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1919629425 290 CGFPPRPAHGDVSVTD--LHPGGTATFHCDSGYQLQGEETLICLNGtrPSWNGETPSC 345
Cdd:pfam00084   1 CPPPPDIPNGKVSATKneYNYGASVSYECDPGYRLVGSPTITCQED--GTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
705-764 3.85e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 50.58  E-value: 3.85e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 705 CADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCysrdTGTPKWSDRVPKC 764
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITC----QEDGTWSPPFPEC 56
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 359-417 4.46e-08

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 51.62  E-value: 4.46e-08
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1919629425  359 GRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDN----DRLMVRSGGSPLSPVI 417
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSDnceyDYVEIYDGPSASSPLL 63
Sushi pfam00084
Sushi repeat (SCR repeat);
464-523 1.18e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 46.34  E-value: 1.18e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1919629425 464 CFAPF-LAHGNVTTTDPEYRPGALATFSCLPGYALEppgPPNAIECVDptEPHWNDTEPAC 523
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRLV---GSPTITCQE--DGTWSPPFPEC 56
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 182-283 8.83e-06

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 45.07  E-value: 8.83e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425  182 GYVESPDLGSPVSRtlgLLDCTYSIHVYPGYGIEIQVQTLNLSQEEE-----LLVLAGggsPGLAPRLLAN--SSMLGEg 254
Cdd:smart00042   1 GTITSPNYPQSYPN---NLDCVWTIRAPPGYRIELQFTDFDLESSDNceydyVEIYDG---PSASSPLLGRfcGSEAPP- 73

                           90       100
                   ....*....|....*....|....*....
gi 1919629425  255 QVLRSPTNRLLLHFQSPRVPRGGGFRIHY 283
Cdd:smart00042  74 PVISSSSNSLTLTFVSDSSVQKRGFSARY 102
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 665-771 1.02e-05

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 48.54  E-value: 1.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 665 GTVLTYQCEPGYELLGSDILTCQWDlSWSAAPPACQKimtCADPgEIANGhrTASDAGFPVGSHVQYRCLPGYSLEGAAM 744
Cdd:PHA02954  150 GEHITINCDVGYEVIGASYISCTAN-SWNVIPSCQQK---CDIP-SLSNG--LISGSTFSIGGVIHLSCKSGFTLTGSPS 222

                          90       100
                  ....*....|....*....|....*..
gi 1919629425 745 LTCYSrdtgtPKWSDRVPKCAFAYEEL 771
Cdd:PHA02954  223 STCID-----GKWNPVLPICVRSNEEF 244
PHA02639 PHA02639
EEV host range protein; Provisional
 676-764 1.39e-05

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 47.74  E-value: 1.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 676 YELLGSDILTCQWDLSWSAAPPACqKIMTCADPGeIANGHRTA--SDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTg 753
Cdd:PHA02639  121 YSLVGNEKITCIQDKSWKPDPPIC-KMINCRFPA-LQNGYINGipSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINAT- 197

                          90
                  ....*....|.
gi 1919629425 754 tpkWSDRVPKC 764
Cdd:PHA02639  198 ---WFPSIPTC 205
PHA02817 PHA02817
EEV Host range protein; Provisional
 664-764 2.17e-05

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 46.47  E-value: 2.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 664 RGTVLTYQCEPG-----YELLGSDILTCQWDLSWSAAPPACqKIMTCADPGeIANGHRTA--SDAGFPVGSHVQYRCLPG 736
Cdd:PHA02817   44 IGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVC-KIIRCRFPA-LQNGFVNGipDSKKFYYESEVSFSCKPG 121

                          90       100
                  ....*....|....*....|....*...
gi 1919629425 737 YSLEGAAMLTCYSRDTgtpkWSDRVPKC 764
Cdd:PHA02817  122 FVLIGTKYSVCGINSS----WIPKVPIC 145
CUB pfam00431
CUB domain;
349-417 4.13e-05

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 43.44  E-value: 4.13e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1919629425 349 CGGTIHNATlGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDED----NDRLMVRSGGSPLSPVI 417
Cdd:pfam00431   1 CGGVLTDSS-GSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHdecgYDYVEIRDGPSASSPLL 72
PHA02639 PHA02639
EEV host range protein; Provisional
 665-764 7.18e-05

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 45.81  E-value: 7.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 665 GTVLTYQCEPGYELLGSDILTCQWDLS---WSAAPPACQkIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLP----GY 737
Cdd:PHA02639   43 GKLIEYTCNTDYALIGDRFRTCIKDKNnaiWSNKAPFCM-LKECNDPPSIINGKIYNKREMYKVGDEIYYVCNEhkgvQY 121

                          90       100
                  ....*....|....*....|....*..
gi 1919629425 738 SLEGAAMLTCysrdTGTPKWSDRVPKC 764
Cdd:PHA02639  122 SLVGNEKITC----IQDKSWKPDPPIC 144
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 467-524 8.90e-05

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 40.91  E-value: 8.90e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1919629425 467 PFLAHGNVTTTDPEYRPGALATFSCLPGYALEppgPPNAIECVDptEPHWNDTEPACK 524
Cdd:cd00033     5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTLV---GSSTITCTE--NGGWSPPPPTCE 57
CUB pfam00431
CUB domain;
173-283 9.15e-05

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 42.67  E-value: 9.15e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 173 CNNNISEGEGYVESPDLGSPVSRtlgLLDCTYSIHVYPGYGIEIQVQTLNLSQEEE-----LLVLAGGGspglaprllAN 247
Cdd:pfam00431   1 CGGVLTDSSGSISSPNYPNPYPP---NKDCVWLIRAPPGFRVKLTFQDFELEDHDEcgydyVEIRDGPS---------AS 68

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1919629425 248 SSMLGE------GQVLRSPTNRLLLHFQSPRVPRGGGFRIHY 283
Cdd:pfam00431  69 SPLLGRfcgsgiPEDIVSSSNQMTIKFVSDASVQKRGFKATY 110
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 467-523 3.63e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 39.05  E-value: 3.63e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1919629425  467 PFLAHGNVTTTDPEYRPGALATFSCLPGYALEppgPPNAIECVDptEPHWNDTEPAC 523
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTLI---GSSTITCLE--NGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 665-764 3.87e-04

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 43.10  E-value: 3.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 665 GTVLTYQCEPGY--ELLGSDILTCQWDlSWSAAPPACQKimTCADPGEIANGHRTASDAGFpvGSHVQYRCLPGYSLEGA 742
Cdd:PHA02927   47 GDTIEYLCLPGYrkQKMGPIYAKCTGT-GWTLFNQCIKR--RCPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQLIGE 121

                          90       100
                  ....*....|....*....|..
gi 1919629425 743 AMLTCYSRDTGTPKWSDRVPKC 764
Cdd:PHA02927  122 SKSYCELGSTGSMVWNPEAPIC 143
PHA02639 PHA02639
EEV host range protein; Provisional
 701-764 1.06e-03

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 41.96  E-value: 1.06e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1919629425 701 KIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYsRDTGTPKWSDRVPKC 764
Cdd:PHA02639   18 KSIYCDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCI-KDKNNAIWSNKAPFC 80
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 276-345 1.54e-03

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 41.18  E-value: 1.54e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1919629425 276 GGGFRIHYQAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPS--WNGETPSC 345
Cdd:PHA02927   72 GTGWTLFNQCIKRRCPSPRDIDNGQLDIGGVDFGSSITYSCNSGYQLIGESKSYCELGSTGSmvWNPEAPIC 143
PHA02831 PHA02831
EEV host range protein; Provisional
 665-764 1.87e-03

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 41.13  E-value: 1.87e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629425 665 GTVLTYQCEPG----YELLGSDILTCqWDLSWSAAPPACqKIMTCADPGeIANGHRTASDAGFPVGSHVQYRCLPGYSLE 740
Cdd:PHA02831   99 GDSVTYACKVNklekYSIVGNETVKC-INKQWVPKYPVC-KLIRCKYPA-LQNGFLNVFEKKFYYGDIVNFKCKKGFILL 175

                          90       100
                  ....*....|....*....|....
gi 1919629425 741 GAAMLTCYSRDTgtpkWSDRVPKC 764
Cdd:PHA02831  176 GSSVSTCDINSI----WYPGIPKC 195
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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