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Conserved domains on  [gi|1331037349|ref|NP_001346815|]
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endosome/lysosome-associated apoptosis and autophagy regulator family member 2 isoform 4 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ephrin_rec_like super family cl06646
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 288-318 1.15e-04

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


The actual alignment was detected with superfamily member pfam07699:

Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 40.41  E-value: 1.15e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1331037349 288 FYNNGSSSCHPCPPGTFSD--GTKECKSCPAGT 318
Cdd:pfam07699   3 YSNTGLEPCIPCPRGTYQPeeGQLSCLACPLGT 35
Ephrin_rec_like super family cl06646
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 173-207 2.99e-03

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


The actual alignment was detected with superfamily member pfam07699:

Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 36.56  E-value: 2.99e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1331037349 173 TSECFPCKPGTFSNKPGSFNCQMCPRNTYSEK-GAK 207
Cdd:pfam07699   8 LEPCIPCPRGTYQPEEGQLSCLACPLGTTTDSpGAT 43
 
Name Accession Description Interval E-value
Ephrin_rec_like pfam07699
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 288-318 1.15e-04

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 40.41  E-value: 1.15e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1331037349 288 FYNNGSSSCHPCPPGTFSD--GTKECKSCPAGT 318
Cdd:pfam07699   3 YSNTGLEPCIPCPRGTYQPeeGQLSCLACPLGT 35
Ephrin_rec_like pfam07699
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 173-207 2.99e-03

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 36.56  E-value: 2.99e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1331037349 173 TSECFPCKPGTFSNKPGSFNCQMCPRNTYSEK-GAK 207
Cdd:pfam07699   8 LEPCIPCPRGTYQPEEGQLSCLACPLGTTTDSpGAT 43
 
Name Accession Description Interval E-value
Ephrin_rec_like pfam07699
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 288-318 1.15e-04

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 40.41  E-value: 1.15e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1331037349 288 FYNNGSSSCHPCPPGTFSD--GTKECKSCPAGT 318
Cdd:pfam07699   3 YSNTGLEPCIPCPRGTYQPeeGQLSCLACPLGT 35
Ephrin_rec_like pfam07699
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 173-207 2.99e-03

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 36.56  E-value: 2.99e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1331037349 173 TSECFPCKPGTFSNKPGSFNCQMCPRNTYSEK-GAK 207
Cdd:pfam07699   8 LEPCIPCPRGTYQPEEGQLSCLACPLGTTTDSpGAT 43
Ephrin_rec_like pfam07699
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 182-212 5.85e-03

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 35.79  E-value: 5.85e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1331037349 182 GTFSNKpGSFNCQMCPRNTY-SEKGAKECIRC 212
Cdd:pfam07699   1 GTYSNT-GLEPCIPCPRGTYqPEEGQLSCLAC 31
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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