NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1244518262|ref|NP_001342544|]
View 

oxidative stress-induced growth inhibitor 2 isoform 2 [Mus musculus]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 1000380)

NAD(P)/FAD-dependent oxidoreductase catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant

CATH:  3.50.50.60
EC:  1.-.-.-
Gene Ontology:  GO:0016491
SCOP:  4000117

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
CzcO super family cl34398
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
117-317 4.66e-07

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


The actual alignment was detected with superfamily member COG2072:

Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 52.17  E-value: 4.66e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1244518262 117 IPHLVLGKGP-PGGAWHNM--EGSMLTISfgNWM-ELPGLQFkdWisskrrnlKGDRVMP--EEIARYYKHYVKVMGLQK 190
Cdd:COG2072    30 IDFVVLEKADdVGGTWRDNryPGLRLDTP--SHLySLPFFPN--W--------SDDPDFPtgDEILAYLEAYADKFGLRR 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1244518262 191 NFRENTYITSVSrlyRDQGDNGsqdrdistkhlqnqkskfikrnWEIrgyqRIAGGSHvpfcLFAENVALATGTLDSPAH 270
Cdd:COG2072    98 PIRFGTEVTSAR---WDEADGR----------------------WTV----TTDDGET----LTARFVVVATGPLSRPKI 144
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1244518262 271 LEVEGEEfPF---VFHSmpefgAAIN-----KGKlcgrvdPVLIVGSGLTAADAV 317
Cdd:COG2072   145 PDIPGLE-DFageQLHS-----ADWRnpvdlAGK------RVLVVGTGASAVQIA 187
 
Name Accession Description Interval E-value
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
117-317 4.66e-07

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 52.17  E-value: 4.66e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1244518262 117 IPHLVLGKGP-PGGAWHNM--EGSMLTISfgNWM-ELPGLQFkdWisskrrnlKGDRVMP--EEIARYYKHYVKVMGLQK 190
Cdd:COG2072    30 IDFVVLEKADdVGGTWRDNryPGLRLDTP--SHLySLPFFPN--W--------SDDPDFPtgDEILAYLEAYADKFGLRR 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1244518262 191 NFRENTYITSVSrlyRDQGDNGsqdrdistkhlqnqkskfikrnWEIrgyqRIAGGSHvpfcLFAENVALATGTLDSPAH 270
Cdd:COG2072    98 PIRFGTEVTSAR---WDEADGR----------------------WTV----TTDDGET----LTARFVVVATGPLSRPKI 144
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1244518262 271 LEVEGEEfPF---VFHSmpefgAAIN-----KGKlcgrvdPVLIVGSGLTAADAV 317
Cdd:COG2072   145 PDIPGLE-DFageQLHS-----ADWRnpvdlAGK------RVLVVGTGASAVQIA 187
PRK12770 PRK12770
putative glutamate synthase subunit beta; Provisional
258-333 7.46e-03

putative glutamate synthase subunit beta; Provisional


Pssm-ID: 237197 [Multi-domain]  Cd Length: 352  Bit Score: 38.43  E-value: 7.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1244518262 258 VALATGTLDSpAHLEVEGEEFPFVFHSMpEFGAAINKGKLC----GRVDP-----VLIVGSGLTAADAVLCAYNNNI-PV 327
Cdd:PRK12770  122 VLIATGTWKS-RKLGIPGEDLPGVYSAL-EYLFRIRAAKLGylpwEKVPPvegkkVVVVGAGLTAVDAALEAVLLGAeKV 199

                  ....*.
gi 1244518262 328 IHVFRR 333
Cdd:PRK12770  200 YLAYRR 205
 
Name Accession Description Interval E-value
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
117-317 4.66e-07

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 52.17  E-value: 4.66e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1244518262 117 IPHLVLGKGP-PGGAWHNM--EGSMLTISfgNWM-ELPGLQFkdWisskrrnlKGDRVMP--EEIARYYKHYVKVMGLQK 190
Cdd:COG2072    30 IDFVVLEKADdVGGTWRDNryPGLRLDTP--SHLySLPFFPN--W--------SDDPDFPtgDEILAYLEAYADKFGLRR 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1244518262 191 NFRENTYITSVSrlyRDQGDNGsqdrdistkhlqnqkskfikrnWEIrgyqRIAGGSHvpfcLFAENVALATGTLDSPAH 270
Cdd:COG2072    98 PIRFGTEVTSAR---WDEADGR----------------------WTV----TTDDGET----LTARFVVVATGPLSRPKI 144
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1244518262 271 LEVEGEEfPF---VFHSmpefgAAIN-----KGKlcgrvdPVLIVGSGLTAADAV 317
Cdd:COG2072   145 PDIPGLE-DFageQLHS-----ADWRnpvdlAGK------RVLVVGTGASAVQIA 187
YdhS COG4529
Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];
242-318 8.25e-05

Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];


Pssm-ID: 443597 [Multi-domain]  Cd Length: 466  Bit Score: 44.95  E-value: 8.25e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1244518262 242 RIAGGSHVPfclfAENVALATGTLdSPAHLEVEGEEFPFVFHSM--PEFGAAINKGklcgrvDPVLIVGSGLTAADAVL 318
Cdd:COG4529   142 TLADGETLR----ADAVVLATGHP-PPAPPPGLAAGSPRYIADPwpPGALARIPPD------ARVLIIGTGLTAIDVVL 209
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
258-320 3.98e-04

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 42.81  E-value: 3.98e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1244518262 258 VALATGTLDsPAHLEVEGEEFPFVFHSMpEFGAAINKGKLCGRVDP----VLIVGSGLTAADAVLCA 320
Cdd:COG0493   210 VFLATGAGK-PRDLGIPGEDLKGVHSAM-DFLTAVNLGEAPDTILAvgkrVVVIGGGNTAMDCARTA 274
PRK12770 PRK12770
putative glutamate synthase subunit beta; Provisional
258-333 7.46e-03

putative glutamate synthase subunit beta; Provisional


Pssm-ID: 237197 [Multi-domain]  Cd Length: 352  Bit Score: 38.43  E-value: 7.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1244518262 258 VALATGTLDSpAHLEVEGEEFPFVFHSMpEFGAAINKGKLC----GRVDP-----VLIVGSGLTAADAVLCAYNNNI-PV 327
Cdd:PRK12770  122 VLIATGTWKS-RKLGIPGEDLPGVYSAL-EYLFRIRAAKLGylpwEKVPPvegkkVVVVGAGLTAVDAALEAVLLGAeKV 199

                  ....*.
gi 1244518262 328 IHVFRR 333
Cdd:PRK12770  200 YLAYRR 205
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH