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Conserved domains on  [gi|1240085951|ref|NP_001341990|]
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complement component receptor 1-like protein isoform 3 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 4-257 8.91e-45

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 154.43  E-value: 8.91e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951   4 CPAPSqlpsaKPINLT--------DESMFPIGTYLLYECLPGYIKRQF-SITCKQDSTWTSAEDKCIRKQCKTPSDPENG 74
Cdd:PHA02927   21 CTIPS-----RPINMKfknsvetdANANYNIGDTIEYLCLPGYRKQKMgPIYAKCTGTGWTLFNQCIKRRCPSPRDIDNG 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951  75 LVHVhTGIQFGSRINYTCNQGYRLIGSSSAVCVI-TDQSVDWDTEAPICEWIPCEIPPGIPNGDffSSTREDFHY-GMVV 152
Cdd:PHA02927   96 QLDI-GGVDFGSSITYSCNSGYQLIGESKSYCELgSTGSMVWNPEAPICESVKCQSPPSISNGR--HNGYEDFYTdGSVV 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951 153 TYRCNTDargkalFNLVGEPSLYCTSndgeiGVWSGPPpqCIELNKCtPPPYVENAVMLSENRSLFSLRDIVEFRCHPGF 232
Cdd:PHA02927  173 TYSCNSG------YSLIGNSGVLCSG-----GEWSDPP--TCQIVKC-PHPTISNGYLSSGFKRSYSYNDNVDFKCKYGY 238

                         250       260
                  ....*....|....*....|....*
gi 1240085951 233 IMKGASSVHCQSLNKWEPELPSCFK 257
Cdd:PHA02927  239 KLSGSSSSTCSPGNTWQPELPKCVR 263
PHA02817 super family cl31508
EEV Host range protein; Provisional
 195-323 8.21e-15

EEV Host range protein; Provisional


The actual alignment was detected with superfamily member PHA02817:

Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 72.67  E-value: 8.21e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951 195 ELNKCTPPPYVENAVMLSEnRSLFSLRDIVEFRCHPG-----FIMKGASSVHCQSLNKWEPELPSCfKGVICRLPQEMSG 269
Cdd:PHA02817   20 DLNKCCYPPSIKNGYIYNK-KTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVC-KIIRCRFPALQNG 97

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1240085951 270 FQKGLGMKKEYYYGENVTLECEDGYTLEGSSQSQCQSDGSWNPLLAKCVSRSIS 323
Cdd:PHA02817   98 FVNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPICSRDNIT 151
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 4-257 8.91e-45

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 154.43  E-value: 8.91e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951   4 CPAPSqlpsaKPINLT--------DESMFPIGTYLLYECLPGYIKRQF-SITCKQDSTWTSAEDKCIRKQCKTPSDPENG 74
Cdd:PHA02927   21 CTIPS-----RPINMKfknsvetdANANYNIGDTIEYLCLPGYRKQKMgPIYAKCTGTGWTLFNQCIKRRCPSPRDIDNG 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951  75 LVHVhTGIQFGSRINYTCNQGYRLIGSSSAVCVI-TDQSVDWDTEAPICEWIPCEIPPGIPNGDffSSTREDFHY-GMVV 152
Cdd:PHA02927   96 QLDI-GGVDFGSSITYSCNSGYQLIGESKSYCELgSTGSMVWNPEAPICESVKCQSPPSISNGR--HNGYEDFYTdGSVV 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951 153 TYRCNTDargkalFNLVGEPSLYCTSndgeiGVWSGPPpqCIELNKCtPPPYVENAVMLSENRSLFSLRDIVEFRCHPGF 232
Cdd:PHA02927  173 TYSCNSG------YSLIGNSGVLCSG-----GEWSDPP--TCQIVKC-PHPTISNGYLSSGFKRSYSYNDNVDFKCKYGY 238

                         250       260
                  ....*....|....*....|....*
gi 1240085951 233 IMKGASSVHCQSLNKWEPELPSCFK 257
Cdd:PHA02927  239 KLSGSSSSTCSPGNTWQPELPKCVR 263
PHA02817 PHA02817
EEV Host range protein; Provisional
 195-323 8.21e-15

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 72.67  E-value: 8.21e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951 195 ELNKCTPPPYVENAVMLSEnRSLFSLRDIVEFRCHPG-----FIMKGASSVHCQSLNKWEPELPSCfKGVICRLPQEMSG 269
Cdd:PHA02817   20 DLNKCCYPPSIKNGYIYNK-KTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVC-KIIRCRFPALQNG 97

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1240085951 270 FQKGLGMKKEYYYGENVTLECEDGYTLEGSSQSQCQSDGSWNPLLAKCVSRSIS 323
Cdd:PHA02817   98 FVNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPICSRDNIT 151
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 127-194 2.34e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 55.55  E-value: 2.34e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1240085951 127 CEIPPGIPNGDFfSSTREDFHYGMVVTYRCNTDargkalFNLVGEPSLYCTSNdgeiGVWSGPPPQCI 194
Cdd:cd00033     1 CPPPPVPENGTV-TGSKGSYSYGSTVTYSCNEG------YTLVGSSTITCTEN----GGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 199-255 3.72e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 54.84  E-value: 3.72e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1240085951  199 CTPPPYVENAVMLSENRSlFSLRDIVEFRCHPGFIMKGASSVHCQSLNKWEPELPSC 255
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT-YSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 277-318 1.75e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 53.24  E-value: 1.75e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1240085951 277 KKEYYYGENVTLECEDGYTLEGSSQSQCQSDGSWNPLLAKCV 318
Cdd:cd00033    16 KGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
199-255 6.92e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 51.35  E-value: 6.92e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1240085951 199 CTPPPYVENAVmLSENRSLFSLRDIVEFRCHPGFIMKGASSVHCQSLNKWEPELPSC 255
Cdd:pfam00084   1 CPPPPDIPNGK-VSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 277-317 2.29e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.83  E-value: 2.29e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 1240085951  277 KKEYYYGENVTLECEDGYTLEGSSQSQCQSDGSWNPLLAKC 317
Cdd:smart00032  16 SGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
277-317 2.56e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 47.11  E-value: 2.56e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1240085951 277 KKEYYYGENVTLECEDGYTLEGSSQSQCQSDGSWNPLLAKC 317
Cdd:pfam00084  16 KNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 4-257 8.91e-45

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 154.43  E-value: 8.91e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951   4 CPAPSqlpsaKPINLT--------DESMFPIGTYLLYECLPGYIKRQF-SITCKQDSTWTSAEDKCIRKQCKTPSDPENG 74
Cdd:PHA02927   21 CTIPS-----RPINMKfknsvetdANANYNIGDTIEYLCLPGYRKQKMgPIYAKCTGTGWTLFNQCIKRRCPSPRDIDNG 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951  75 LVHVhTGIQFGSRINYTCNQGYRLIGSSSAVCVI-TDQSVDWDTEAPICEWIPCEIPPGIPNGDffSSTREDFHY-GMVV 152
Cdd:PHA02927   96 QLDI-GGVDFGSSITYSCNSGYQLIGESKSYCELgSTGSMVWNPEAPICESVKCQSPPSISNGR--HNGYEDFYTdGSVV 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951 153 TYRCNTDargkalFNLVGEPSLYCTSndgeiGVWSGPPpqCIELNKCtPPPYVENAVMLSENRSLFSLRDIVEFRCHPGF 232
Cdd:PHA02927  173 TYSCNSG------YSLIGNSGVLCSG-----GEWSDPP--TCQIVKC-PHPTISNGYLSSGFKRSYSYNDNVDFKCKYGY 238

                         250       260
                  ....*....|....*....|....*
gi 1240085951 233 IMKGASSVHCQSLNKWEPELPSCFK 257
Cdd:PHA02927  239 KLSGSSSSTCSPGNTWQPELPKCVR 263
PHA02639 PHA02639
EEV host range protein; Provisional
 127-318 1.10e-21

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 93.58  E-value: 1.10e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951 127 CEIPPGIPNGdFFSSTREDFHYGMVVTYRCNTDargkalFNLVGEPSLYCTsNDGEIGVWSGPPPQCIeLNKCTPPPYVE 206
Cdd:PHA02639   22 CDKPDDISNG-FITELMEKYEIGKLIEYTCNTD------YALIGDRFRTCI-KDKNNAIWSNKAPFCM-LKECNDPPSII 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951 207 NAVMLSEnRSLFSLRDIVEFRC--HPG--FIMKGASSVHCQSLNKWEPELPSCfKGVICRLPQEMSGFQKGLGMKKEYYY 282
Cdd:PHA02639   93 NGKIYNK-REMYKVGDEIYYVCneHKGvqYSLVGNEKITCIQDKSWKPDPPIC-KMINCRFPALQNGYINGIPSNKKFYY 170

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1240085951 283 GENVTLECEDGYTLEGSSQSQCQSDGSWNPLLAKCV 318
Cdd:PHA02639  171 KTRVGFSCKSGFDLVGEKYSTCNINATWFPSIPTCV 206
PHA02639 PHA02639
EEV host range protein; Provisional
 65-257 1.01e-18

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 85.10  E-value: 1.01e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951  65 CKTPSDPENGLV-HVHTGIQFGSRINYTCNQGYRLIGSSSAVCVITDQSVDWDTEAPICEWIPCEIPPGIPNGDFFSStR 143
Cdd:PHA02639   22 CDKPDDISNGFItELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAIWSNKAPFCMLKECNDPPSIINGKIYNK-R 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951 144 EDFHYGMVVTYRCNtDARGkALFNLVGEPSLYCTSNDGeigvWSGPPPQCIELNkCTPPPYVENAVMLSENRSLFSLRDI 223
Cdd:PHA02639  101 EMYKVGDEIYYVCN-EHKG-VQYSLVGNEKITCIQDKS----WKPDPPICKMIN-CRFPALQNGYINGIPSNKKFYYKTR 173

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1240085951 224 VEFRCHPGFIMKGASSVHCQSLNKWEPELPSCFK 257
Cdd:PHA02639  174 VGFSCKSGFDLVGEKYSTCNINATWFPSIPTCVR 207
PHA02817 PHA02817
EEV Host range protein; Provisional
 195-323 8.21e-15

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 72.67  E-value: 8.21e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951 195 ELNKCTPPPYVENAVMLSEnRSLFSLRDIVEFRCHPG-----FIMKGASSVHCQSLNKWEPELPSCfKGVICRLPQEMSG 269
Cdd:PHA02817   20 DLNKCCYPPSIKNGYIYNK-KTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVC-KIIRCRFPALQNG 97

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1240085951 270 FQKGLGMKKEYYYGENVTLECEDGYTLEGSSQSQCQSDGSWNPLLAKCVSRSIS 323
Cdd:PHA02817   98 FVNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPICSRDNIT 151
PHA02831 PHA02831
EEV host range protein; Provisional
 154-322 1.42e-12

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 66.94  E-value: 1.42e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951 154 YRCNTDargkalFNlvgepSLYCTSNDGEigvWSgPPPQCIELNKCTPPPYVENAvMLSENRSLFSLRDIVEFRCHPGFI 233
Cdd:PHA02831   48 YKCNNN------FD-----KVFVTCNNGS---WS-TKNMCIGKRNCKDPVTILNG-YIKNKKDQYSFGDSVTYACKVNKL 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951 234 MK----GASSVHCQSlNKWEPELPSCfKGVICRLPQEMSGFQKGLgmKKEYYYGENVTLECEDGYTLEGSSQSQCQSDGS 309
Cdd:PHA02831  112 EKysivGNETVKCIN-KQWVPKYPVC-KLIRCKYPALQNGFLNVF--EKKFYYGDIVNFKCKKGFILLGSSVSTCDINSI 187

                         170
                  ....*....|...
gi 1240085951 310 WNPLLAKCVSRSI 322
Cdd:PHA02831  188 WYPGIPKCVKDKV 200
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 127-194 2.34e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 55.55  E-value: 2.34e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1240085951 127 CEIPPGIPNGDFfSSTREDFHYGMVVTYRCNTDargkalFNLVGEPSLYCTSNdgeiGVWSGPPPQCI 194
Cdd:cd00033     1 CPPPPVPENGTV-TGSKGSYSYGSTVTYSCNEG------YTLVGSSTITCTEN----GGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 199-255 3.72e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 54.84  E-value: 3.72e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1240085951  199 CTPPPYVENAVMLSENRSlFSLRDIVEFRCHPGFIMKGASSVHCQSLNKWEPELPSC 255
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT-YSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 199-255 8.39e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.01  E-value: 8.39e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1240085951 199 CTPPPYVENAVMLSENRSlFSLRDIVEFRCHPGFIMKGASSVHCQSLNKWEPELPSC 255
Cdd:cd00033     1 CPPPPVPENGTVTGSKGS-YSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 3-194 1.04e-09

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 58.91  E-value: 1.04e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951   3 HCPAPSQLPSAKPINLTDEsmFPIGTYLLYECLPGY--IKRQFSiTC---KQDSTWTSAEDKCIRKQCKTPSDPENGLVH 77
Cdd:PHA02639   21 YCDKPDDISNGFITELMEK--YEIGKLIEYTCNTDYalIGDRFR-TCikdKNNAIWSNKAPFCMLKECNDPPSIINGKIY 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951  78 VHTGI-QFGSRINYTCNQ----GYRLIGSSSAVCVitdQSVDWDTEAPICEWIPCEIPP---GIPNGdffSSTREDFHYG 149
Cdd:PHA02639   98 NKREMyKVGDEIYYVCNEhkgvQYSLVGNEKITCI---QDKSWKPDPPICKMINCRFPAlqnGYING---IPSNKKFYYK 171

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1240085951 150 MVVTYRCntdargKALFNLVGEPSLYCTSNdgeiGVWSGPPPQCI 194
Cdd:PHA02639  172 TRVGFSC------KSGFDLVGEKYSTCNIN----ATWFPSIPTCV 206
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 65-123 1.15e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 53.62  E-value: 1.15e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951  65 CKTPSDPENGLVHVHTGI-QFGSRINYTCNQGYRLIGSSSAVCVITDQsvdWDTEAPICE 123
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSySYGSTVTYSCNEGYTLVGSSTITCTENGG---WSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 277-318 1.75e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 53.24  E-value: 1.75e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1240085951 277 KKEYYYGENVTLECEDGYTLEGSSQSQCQSDGSWNPLLAKCV 318
Cdd:cd00033    16 KGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 127-193 2.55e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.53  E-value: 2.55e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1240085951  127 CEIPPGIPNGdFFSSTREDFHYGMVVTYRCNTDargkalFNLVGEPSLYCTSNdgeiGVWSGPPPQC 193
Cdd:smart00032   1 CPPPPDIENG-TVTSSSGTYSYGDTVTYSCDPG------YTLIGSSTITCLEN----GTWSPPPPTC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 30-195 3.27e-09

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 56.92  E-value: 3.27e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951  30 LLYECLPGYIKrqFSITCKQDStWtSAEDKCIRKQ-CKTPSDPENGLV-HVHTGIQFGSRINYTCN----QGYRLIGSSS 103
Cdd:PHA02831   46 LEYKCNNNFDK--VFVTCNNGS-W-STKNMCIGKRnCKDPVTILNGYIkNKKDQYSFGDSVTYACKvnklEKYSIVGNET 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951 104 AVCVitdqSVDWDTEAPICEWIPCEIPpGIPNGdFFSSTREDFHYGMVVTYRCNTDargkalFNLVGEPSLYCTSNdgei 183
Cdd:PHA02831  122 VKCI----NKQWVPKYPVCKLIRCKYP-ALQNG-FLNVFEKKFYYGDIVNFKCKKG------FILLGSSVSTCDIN---- 185

                         170
                  ....*....|..
gi 1240085951 184 GVWSGPPPQCIE 195
Cdd:PHA02831  186 SIWYPGIPKCVK 197
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 65-122 4.16e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.14  E-value: 4.16e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1240085951   65 CKTPSDPENGLVHVHTG-IQFGSRINYTCNQGYRLIGSSSAVCVitdQSVDWDTEAPIC 122
Cdd:smart00032   1 CPPPPDIENGTVTSSSGtYSYGDTVTYSCDPGYTLIGSSTITCL---ENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
199-255 6.92e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 51.35  E-value: 6.92e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1240085951 199 CTPPPYVENAVmLSENRSLFSLRDIVEFRCHPGFIMKGASSVHCQSLNKWEPELPSC 255
Cdd:pfam00084   1 CPPPPDIPNGK-VSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 277-317 2.29e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.83  E-value: 2.29e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 1240085951  277 KKEYYYGENVTLECEDGYTLEGSSQSQCQSDGSWNPLLAKC 317
Cdd:smart00032  16 SGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
65-122 3.74e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 49.42  E-value: 3.74e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1240085951  65 CKTPSDPENGLVHV-HTGIQFGSRINYTCNQGYRLIGSSSAVCVITDQsvdWDTEAPIC 122
Cdd:pfam00084   1 CPPPPDIPNGKVSAtKNEYNYGASVSYECDPGYRLVGSPTITCQEDGT---WSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
127-193 7.97e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.26  E-value: 7.97e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1240085951 127 CEIPPGIPNGDFfSSTREDFHYGMVVTYRCNtdaRGkalFNLVGEPSLYCTSNdgeiGVWSGPPPQC 193
Cdd:pfam00084   1 CPPPPDIPNGKV-SATKNEYNYGASVSYECD---PG---YRLVGSPTITCQED----GTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
277-317 2.56e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 47.11  E-value: 2.56e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1240085951 277 KKEYYYGENVTLECEDGYTLEGSSQSQCQSDGSWNPLLAKC 317
Cdd:pfam00084  16 KNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
4-60 5.89e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.95  E-value: 5.89e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1240085951   4 CPAPSQLPSAKPINLTDEsmFPIGTYLLYECLPGYIKR-QFSITCKQDSTWTSAEDKC 60
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNE--YNYGASVSYECDPGYRLVgSPTITCQEDGTWSPPFPEC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 65-318 1.20e-06

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 49.70  E-value: 1.20e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951  65 CKTPSDPENGLVHVHTGIQFGSRINYTCNQGYRLIgSSSAVCvitdQSVDWDTEAPiCEWIpCEIppgipnGDFFSS--T 142
Cdd:PHA02954   21 CTVPTMNNAKLTSTETSFNDKQKVTFTCDSGYYSL-DPNAVC----ETDKWKYENP-CKKM-CTV------SDYVSElyD 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951 143 REDFHYGMVVTYRCNTDARgkalfnlvgepSLYCTSNDGEIGvWSG----PPPQC--IELNKCTPPPYVENavmlsenrs 216
Cdd:PHA02954   88 KPLYEVNSTITLICKDETK-----------YFRCEEKNGNTS-WNDtvtcPNAECqpLQLEHGSCQPVKEK--------- 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951 217 lFSLRDIVEFRCHPGFIMKGASSVHCQSlNKWEPeLPSCFKGviCRLPQEMSGFQKGlgmkKEYYYGENVTLECEDGYTL 296
Cdd:PHA02954  147 -YSFGEHITINCDVGYEVIGASYISCTA-NSWNV-IPSCQQK--CDIPSLSNGLISG----STFSIGGVIHLSCKSGFTL 217

                         250       260
                  ....*....|....*....|..
gi 1240085951 297 EGSSQSQCqSDGSWNPLLAKCV 318
Cdd:PHA02954  218 TGSPSSTC-IDGKWNPVLPICV 238
PHA02817 PHA02817
EEV Host range protein; Provisional
 60-198 1.58e-05

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 45.70  E-value: 1.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951  60 CIRKQCKTPSDPENGLVH-VHTGIQFGSRINYTCNQG-----YRLIGSSSAVCvitDQSVDWDTEAPICEWIPCEIPP-- 131
Cdd:PHA02817   19 CDLNKCCYPPSIKNGYIYnKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIIC---EKDGKWNKEFPVCKIIRCRFPAlq 95

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1240085951 132 -----GIPNGdffsstrEDFHYGMVVTYRCntdargKALFNLVGEPSLYCTSNDgeigVWSGPPPQCIELNK 198
Cdd:PHA02817   96 ngfvnGIPDS-------KKFYYESEVSFSC------KPGFVLIGTKYSVCGINS----SWIPKVPICSRDNI 150
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 4-61 6.26e-05

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 40.14  E-value: 6.26e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1240085951   4 CPAPSQLPSAKPINLTDEsmFPIGTYLLYECLPGY-IKRQFSITCKQDSTWTSAEDKCI 61
Cdd:cd00033     1 CPPPPVPENGTVTGSKGS--YSYGSTVTYSCNEGYtLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 4-60 2.56e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 38.66  E-value: 2.56e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1240085951    4 CPAPSQLPSAKPINLTDEsmFPIGTYLLYECLPGY-IKRQFSITCKQDSTWTSAEDKC 60
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT--YSYGDTVTYSCDPGYtLIGSSTITCLENGTWSPPPPTC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 1-122 1.30e-03

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 40.03  E-value: 1.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951   1 MGHCPAPSQLPSAKPINltDESMFPIGTYLLYEClPGYIKRQFS------ITCKQDSTWTSAEDKCIRKQCKTPSdPENG 74
Cdd:PHA02639   82 LKECNDPPSIINGKIYN--KREMYKVGDEIYYVC-NEHKGVQYSlvgnekITCIQDKSWKPDPPICKMINCRFPA-LQNG 157

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1240085951  75 LVH---VHTGIQFGSRINYTCNQGYRLIGSSSAVCVItdqSVDWDTEAPIC 122
Cdd:PHA02639  158 YINgipSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNI---NATWFPSIPTC 205
PHA02817 PHA02817
EEV Host range protein; Provisional
 45-122 1.70e-03

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 39.54  E-value: 1.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951  45 ITCKQDSTWTSAEDKCIRKQCKTPSdPENGLVHvhtGIQ------FGSRINYTCNQGYRLIGSSSAVCVITDQsvdWDTE 118
Cdd:PHA02817   69 IICEKDGKWNKEFPVCKIIRCRFPA-LQNGFVN---GIPdskkfyYESEVSFSCKPGFVLIGTKYSVCGINSS---WIPK 141


                  ....
gi 1240085951 119 APIC 122
Cdd:PHA02817  142 VPIC 145
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 44-202 2.30e-03

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 39.30  E-value: 2.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951  44 SITCKQDSTWTSAEDK-----------CIRKQCKTPSDPENGLVHVHTGIQFGSRINYTCNQGYRLIGSSSAVCVITDQS 112
Cdd:PHA02954   98 TLICKDETKYFRCEEKngntswndtvtCPNAECQPLQLEHGSCQPVKEKYSFGEHITINCDVGYEVIGASYISCTANSWN 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951 113 VdwdteAPICEWiPCEIpPGIPNGDFFSSTredFHYGMVVTYRCntdargKALFNLVGEPSLYCTSndgeiGVWSGPPPQ 192
Cdd:PHA02954  178 V-----IPSCQQ-KCDI-PSLSNGLISGST---FSIGGVIHLSC------KSGFTLTGSPSSTCID-----GKWNPVLPI 236

                         170
                  ....*....|
gi 1240085951 193 CIELNKCTPP 202
Cdd:PHA02954  237 CVRSNEEFDP 246
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 143-257 4.47e-03

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 38.53  E-value: 4.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1240085951 143 REDFHYGMVVTYRCNTDargkalFNLVGEPSLYCTSNDGEIgvwsgpPPQCIElnKCTPPPYVENAVmlseNRSLFSLRD 222
Cdd:PHA02954  144 KEKYSFGEHITINCDVG------YEVIGASYISCTANSWNV------IPSCQQ--KCDIPSLSNGLI----SGSTFSIGG 205

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1240085951 223 IVEFRCHPGFIMKGASSVHCQSlNKWEPELPSCFK 257
Cdd:PHA02954  206 VIHLSCKSGFTLTGSPSSTCID-GKWNPVLPICVR 239
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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