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Conserved domains on  [gi|1237938158|ref|NP_001341387|]
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phospholipid phosphatase 5 isoform 8 [Homo sapiens]

Protein Classification

phosphatase PAP2 family protein( domain architecture ID 10130247)

type 2 phosphatidic acid phosphatase (PAP2) family protein similar to Homo sapiens phospholipid phosphatase that catalyzes the conversion of phosphatidic acid to diacylglycerol

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PAP2_containing_1_like cd03390
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. ...
 2-99 2.53e-54

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both diacylglycerol pyrophosphate phosphatase activity as well as phosphatidate (PA) phosphatase activity, they may have a more generic housekeeping role in lipid metabolism.


:

Pssm-ID: 239484 [Multi-domain]  Cd Length: 193  Bit Score: 168.55  E-value: 2.53e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237938158   2 CTGDKDVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKLHCFTPqgRGKSWRFCAFLSPLLFAAVIALSRTCDYKHHWQDV 81
Cdd:cd03390    98 CTGDPGVLKEGRKSFPSGHSSFAFAGLGFLSLYLAGKLHIFDP--RGSSWRLLLALLPLLLAILVAVSRTRDYRHHFSDV 175

                          90
                  ....*....|....*...
gi 1237938158  82 LVGSMIGMTFAYVCYRQY 99
Cdd:cd03390   176 IAGSLIGLIIAYLSYRQY 193
 
Name Accession Description Interval E-value
PAP2_containing_1_like cd03390
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. ...
 2-99 2.53e-54

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both diacylglycerol pyrophosphate phosphatase activity as well as phosphatidate (PA) phosphatase activity, they may have a more generic housekeeping role in lipid metabolism.


Pssm-ID: 239484 [Multi-domain]  Cd Length: 193  Bit Score: 168.55  E-value: 2.53e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237938158   2 CTGDKDVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKLHCFTPqgRGKSWRFCAFLSPLLFAAVIALSRTCDYKHHWQDV 81
Cdd:cd03390    98 CTGDPGVLKEGRKSFPSGHSSFAFAGLGFLSLYLAGKLHIFDP--RGSSWRLLLALLPLLLAILVAVSRTRDYRHHFSDV 175

                          90
                  ....*....|....*...
gi 1237938158  82 LVGSMIGMTFAYVCYRQY 99
Cdd:cd03390   176 IAGSLIGLIIAYLSYRQY 193
PLN02250 PLN02250
lipid phosphate phosphatase
 1-111 1.08e-39

lipid phosphate phosphatase


Pssm-ID: 215139  Cd Length: 314  Bit Score: 135.05  E-value: 1.08e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237938158   1 MCTGDKDVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKLHCFtpQGRGKSWRFCAFLSPLLFAAVIALSRTCDYKHHWQD 80
Cdd:PLN02250  148 LCTGAKSVIKEGHKSFPSGHTSWSFAGLGFLSLYLSGKIRVF--DRRGHVAKLCIVFLPLLVAALVGVSRVDDYWHHWQD 225

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1237938158  81 VLVGSMIGMTFAYVCYRQYYPPLTDAECHKP 111
Cdd:PLN02250  226 VFAGALIGLTVASFCYLQFFPPPYDIDGWGP 256
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 11-100 3.96e-18

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 74.38  E-value: 3.96e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237938158  11 EGRKSFPSGHSSFAFAGLAFASFYLAGklhcftpqgRGKSWRFCAFLSPLLFAAVIALSRTCDYKHHWQDVLVGSMIGMT 90
Cdd:pfam01569  43 GLGYSFPSGHSATAFALALLLALLLRR---------LRKIVRVLLALLLLVLALLVGLSRLYLGVHFPSDVLAGALIGIL 113

                          90
                  ....*....|
gi 1237938158  91 FAYVCYRQYY 100
Cdd:pfam01569 114 LALLVYRLVP 123
acidPPc smart00014
Acid phosphatase homologues;
1-96 1.05e-17

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 73.15  E-value: 1.05e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237938158    1 MCTGDKDVVNEGRKSFPSGHSSFAFAGLAFASFYLagklhcftpQGRGKSWRFCAFLspLLFAAVIALSRTCDYKHHWQD 80
Cdd:smart00014  32 CCTPNFLLTLEAGYSFPSGHTAFAFAFALFLLLYL---------PARAGRKLLIFLL--LLLALVVGFSRVYLGAHWPSD 100

                           90
                   ....*....|....*.
gi 1237938158   81 VLVGSMIGMTFAYVCY 96
Cdd:smart00014 101 VLAGSLLGILIAAVLF 116
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 8-99 5.71e-10

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 54.28  E-value: 5.71e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237938158   8 VVNEGRKSFPSGHSSFAFAGLAFASFYLagklhcftpqgrgksWRFCAFLSPLLFAAVIALSRTCDYKHHWQDVLVGSMI 87
Cdd:COG0671   111 LGTAGGYSFPSGHAAAAFALALVLALLL---------------PRRWLAALLLALALLVGLSRVYLGVHYPSDVLAGALL 175

                          90
                  ....*....|..
gi 1237938158  88 GMTFAYVCYRQY 99
Cdd:COG0671   176 GLAIALLLLALL 187
 
Name Accession Description Interval E-value
PAP2_containing_1_like cd03390
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. ...
 2-99 2.53e-54

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both diacylglycerol pyrophosphate phosphatase activity as well as phosphatidate (PA) phosphatase activity, they may have a more generic housekeeping role in lipid metabolism.


Pssm-ID: 239484 [Multi-domain]  Cd Length: 193  Bit Score: 168.55  E-value: 2.53e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237938158   2 CTGDKDVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKLHCFTPqgRGKSWRFCAFLSPLLFAAVIALSRTCDYKHHWQDV 81
Cdd:cd03390    98 CTGDPGVLKEGRKSFPSGHSSFAFAGLGFLSLYLAGKLHIFDP--RGSSWRLLLALLPLLLAILVAVSRTRDYRHHFSDV 175

                          90
                  ....*....|....*...
gi 1237938158  82 LVGSMIGMTFAYVCYRQY 99
Cdd:cd03390   176 IAGSLIGLIIAYLSYRQY 193
PLN02250 PLN02250
lipid phosphate phosphatase
 1-111 1.08e-39

lipid phosphate phosphatase


Pssm-ID: 215139  Cd Length: 314  Bit Score: 135.05  E-value: 1.08e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237938158   1 MCTGDKDVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKLHCFtpQGRGKSWRFCAFLSPLLFAAVIALSRTCDYKHHWQD 80
Cdd:PLN02250  148 LCTGAKSVIKEGHKSFPSGHTSWSFAGLGFLSLYLSGKIRVF--DRRGHVAKLCIVFLPLLVAALVGVSRVDDYWHHWQD 225

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1237938158  81 VLVGSMIGMTFAYVCYRQYYPPLTDAECHKP 111
Cdd:PLN02250  226 VFAGALIGLTVASFCYLQFFPPPYDIDGWGP 256
PLN02731 PLN02731
Putative lipid phosphate phosphatase
 1-127 3.18e-34

Putative lipid phosphate phosphatase


Pssm-ID: 178332  Cd Length: 333  Bit Score: 121.29  E-value: 3.18e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237938158   1 MCTGDKDVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKLHCFtpQGRGKSWRFCAFLSPLLFAAVIALSRTCDYKHHWQD 80
Cdd:PLN02731  166 ICHGDKSVIREGHKSFPSGHTSWSFSGLGFLSLYLSGKIQAF--DGKGHVAKLCIVILPLLFAALVGISRVDDYWHHWQD 243

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1237938158  81 VLVGSMIGMTFAYVCYRQYYPPLTDAECHKPFQDKLVLSTAQKPGDS 127
Cdd:PLN02731  244 VFAGGLLGLAISTICYLQFFPPPYHTEGWGPYAYFQVLEAARVQGAA 290
PLN02715 PLN02715
lipid phosphate phosphatase
 1-127 1.93e-29

lipid phosphate phosphatase


Pssm-ID: 178317 [Multi-domain]  Cd Length: 327  Bit Score: 108.60  E-value: 1.93e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237938158   1 MCTGDKDVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKLHCFTPQGRGKswRFCAFLSPLLFAAVIALSRTCDYKHHWQD 80
Cdd:PLN02715  172 ICHGKAAEVKEGHKSFPSGHTSWSFAGLTFLSLYLSGKIKAFNGEGHVA--KLCLVIFPLLAACLVGISRVDDYWHHWQD 249

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1237938158  81 VLVGSMIGMTFAYVCYRQYYPPLTDAECHKPF------QDKLVLSTAQKPGDS 127
Cdd:PLN02715  250 VFAGALIGILVAAFCYRQFYPNPYHEEGWGPYayfkaaQERGVPVASSQNGDA 302
PAP2_wunen cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid ...
 2-94 1.34e-22

PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the survival of PGCs and is essential in the migration process of these cells towards the somatic gonadal precursors.


Pssm-ID: 239479  Cd Length: 150  Bit Score: 86.53  E-value: 1.34e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237938158   2 CTGDKDVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKLhcftpqgrgkSWRFCAFLSPLL------FAAVIALSRTCDYK 75
Cdd:cd03384    60 CTGDPDLIREARLSFPSGHASLSMYAAVFLALYLQARL----------KLRGSRLLRPLLqflllaLALYVGLSRISDYK 129

                          90
                  ....*....|....*....
gi 1237938158  76 HHWQDVLVGSMIGMTFAYV 94
Cdd:cd03384   130 HHWSDVLAGALLGSVIALF 148
PAP2_like cd01610
PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, ...
 3-96 1.14e-19

PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid phosphatase, vanadium chloroperoxidases, vanadium bromoperoxidases, and several other mostly uncharacterized subfamilies. Several members of this superfamily have been predicted to be transmembrane proteins.


Pssm-ID: 238813 [Multi-domain]  Cd Length: 122  Bit Score: 78.27  E-value: 1.14e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237938158   3 TGDKDVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKLhcftpqgrgksWRFCAFLSPLLFAAVIALSRTCDYKHHWQDVL 82
Cdd:cd01610    40 DGDPLLLTEGGYSFPSGHAAFAFALALFLALLLPRRL-----------LRLLLGLLLLLLALLVGLSRVYLGVHYPSDVL 108

                          90
                  ....*....|....
gi 1237938158  83 VGSMIGMTFAYVCY 96
Cdd:cd01610   109 AGALLGILVALLVL 122
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 11-100 3.96e-18

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 74.38  E-value: 3.96e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237938158  11 EGRKSFPSGHSSFAFAGLAFASFYLAGklhcftpqgRGKSWRFCAFLSPLLFAAVIALSRTCDYKHHWQDVLVGSMIGMT 90
Cdd:pfam01569  43 GLGYSFPSGHSATAFALALLLALLLRR---------LRKIVRVLLALLLLVLALLVGLSRLYLGVHFPSDVLAGALIGIL 113

                          90
                  ....*....|
gi 1237938158  91 FAYVCYRQYY 100
Cdd:pfam01569 114 LALLVYRLVP 123
acidPPc smart00014
Acid phosphatase homologues;
1-96 1.05e-17

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 73.15  E-value: 1.05e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237938158    1 MCTGDKDVVNEGRKSFPSGHSSFAFAGLAFASFYLagklhcftpQGRGKSWRFCAFLspLLFAAVIALSRTCDYKHHWQD 80
Cdd:smart00014  32 CCTPNFLLTLEAGYSFPSGHTAFAFAFALFLLLYL---------PARAGRKLLIFLL--LLLALVVGFSRVYLGAHWPSD 100

                           90
                   ....*....|....*.
gi 1237938158   81 VLVGSMIGMTFAYVCY 96
Cdd:smart00014 101 VLAGSLLGILIAAVLF 116
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 8-99 5.71e-10

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 54.28  E-value: 5.71e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237938158   8 VVNEGRKSFPSGHSSFAFAGLAFASFYLagklhcftpqgrgksWRFCAFLSPLLFAAVIALSRTCDYKHHWQDVLVGSMI 87
Cdd:COG0671   111 LGTAGGYSFPSGHAAAAFALALVLALLL---------------PRRWLAALLLALALLVGLSRVYLGVHYPSDVLAGALL 175

                          90
                  ....*....|..
gi 1237938158  88 GMTFAYVCYRQY 99
Cdd:COG0671   176 GLAIALLLLALL 187
PAP2_like_5 cd03394
PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 6-93 5.77e-10

PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239488 [Multi-domain]  Cd Length: 106  Bit Score: 52.72  E-value: 5.77e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237938158   6 KDVVNEGRKSFPSGHSSFAFAGLAFASFYLagklhcftpqgrGKSWrfcAFLSPLLFAAVIALSRTCDYKHHWQDVLVGS 85
Cdd:cd03394    31 PDGSNNGYRSFPSGHTASAFAAATFLQYRY------------GWRW---YGIPAYALASLVGASRVVANRHWLSDVLAGA 95


                  ....*...
gi 1237938158  86 MIGMTFAY 93
Cdd:cd03394    96 AIGILVGY 103
PAP2_lipid_A_1_phosphatase cd03389
PAP2_like proteins, Lipid A 1-phosphatase subfamily. Lipid A 1-phosphatase, or LpxE from ...
 15-99 2.48e-08

PAP2_like proteins, Lipid A 1-phosphatase subfamily. Lipid A 1-phosphatase, or LpxE from Francisella novicida selectively dephosphorylates lipid A at the 1-position. Lipid A is the membrane-anchor component of lipopolysaccharides (LPS), the major constituents of the outer membrane in many gram-negative bacteria.


Pssm-ID: 239483  Cd Length: 186  Bit Score: 50.01  E-value: 2.48e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237938158  15 SFPSGHSSFAFAgLAFASFYLAGKlhcftpqgrgksWRFCAflspLLFAAVIALSRTCDYKHHWQDVLVGSMIGMTFAYV 94
Cdd:cd03389   119 SFPSGHSATAGA-AAAALALLFPR------------YRWAF----ILLALLIAFSRVIVGAHYPSDVIAGSLLGAVTALA 181


                  ....*
gi 1237938158  95 CYRQY 99
Cdd:cd03389   182 LYQRF 186
PAP2_like_2 cd03392
PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 7-99 1.56e-07

PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239486  Cd Length: 182  Bit Score: 47.60  E-value: 1.56e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237938158   7 DVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKLHcftpqgrGKSWRFCAFLSPLLFAAVIALSRTcdYKH-HW-QDVLVG 84
Cdd:cd03392    94 LLVPEGGYSFPSGHAMGATVLYGFLAYLLARRLP-------RRRVRILLLILAAILILLVGLSRL--YLGvHYpSDVLAG 164

                          90
                  ....*....|....*
gi 1237938158  85 SMIGMTFAYVCYRQY 99
Cdd:cd03392   165 WLLGLAWLALLILLY 179
PAP2_dolichyldiphosphatase cd03382
PAP2_like proteins, dolichyldiphosphatase subfamily. Dolichyldiphosphatase is a ...
 16-96 1.11e-05

PAP2_like proteins, dolichyldiphosphatase subfamily. Dolichyldiphosphatase is a membrane-associated protein located in the endoplasmic reticulum and hydrolyzes dolichyl pyrophosphate, as well as dolichylmonophosphate at a low rate. The enzyme is necessary for maintaining proper levels of dolichol-linked oligosaccharides and protein N-glycosylation, and might play a role in re-utilization of the glycosyl carrier lipid for additional rounds of lipid intermediate biosynthesis after its release during protein N-glycosylation reactions.


Pssm-ID: 239477  Cd Length: 159  Bit Score: 42.26  E-value: 1.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237938158  16 FPSGHSSFAFaglaFASFYLAGKLHCFTPQGRGKSWRFCAFLSPLLFAAVIALSRTCDYKHHWQDVLVGSMIGMTFAYVC 95
Cdd:cd03382    83 MPSSHSQFMG----FFAVYLLLFIYLRLGRLNSLVSRFLLSLGLLLLALLVSYSRVYLGYHTVSQVVVGAIVGILLGILW 158


                  .
gi 1237938158  96 Y 96
Cdd:cd03382   159 F 159
PAP2_containing_2_like cd03391
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. ...
 15-88 2.42e-05

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to eukaryota, lacks functional characterization and may act as a membrane-associated phosphatidic acid phosphatase.


Pssm-ID: 239485 [Multi-domain]  Cd Length: 159  Bit Score: 41.53  E-value: 2.42e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1237938158  15 SFPSGHSSFAFAGLAFASFYLAGKLHcftpqgrgkswrfcaFLSPL-LFAAVIALSRTCDYKHHWQDVLVGSMIG 88
Cdd:cd03391    92 SFPSGHASRAAFVARFLLNHLVLAVP---------------LRVLLvLWATVVGISRVLLGRHHVLDVLAGAFLG 151
PAP2_like_4 cd03395
PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 12-97 1.14e-04

PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239489  Cd Length: 177  Bit Score: 39.55  E-value: 1.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237938158  12 GRKSFPSGHSSFAFAGLAFASFYlagklhcftpqgrgksWRFCAFLSPLLF-AAVIALSRTCDYKHHWQDVLVGSMIGMT 90
Cdd:cd03395   102 GSYSFASSHAANSFALALFIWLF----------------FRRGLFSPVLLLwALLVGYSRVYVGVHYPGDVIAGALIGII 165


                  ....*..
gi 1237938158  91 FAYVCYR 97
Cdd:cd03395   166 SGLLFYL 172
COG3907 COG3907
Membrane-associated enzyme, PAP2 (acid phosphatase) superfamily [General function prediction ...
 14-70 6.95e-03

Membrane-associated enzyme, PAP2 (acid phosphatase) superfamily [General function prediction only];


Pssm-ID: 443113  Cd Length: 236  Bit Score: 34.87  E-value: 6.95e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1237938158  14 KSFPSGHSSfafAGLAFASFYLAGKlhcftpqGRGKSWRFCAFLSPLLFAAVIALSR 70
Cdd:COG3907   151 RCFPAGHAS---AGFALLALYFLLR-------RRRPRLARLGLAAGLALGLLMGLAQ 197
PAP2_like_6 cd03396
PAP2_like_6 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 10-97 8.34e-03

PAP2_like_6 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which mainly contains bacterial proteins, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239490  Cd Length: 197  Bit Score: 34.58  E-value: 8.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237938158  10 NEGRKSFPSGHSSFAFAGLAFASFYLAgklhcftpqgRGKSWRFCAFLSPLLFAAVIALSRTCDYKHHWQDVLVGSMIGM 89
Cdd:cd03396   118 CGKGCSFPSGHASAGFALLALYFLFRR----------RRPRLARLVLAAGLALGALMGLARMARGAHFLSDVLWSLLLVW 187


                  ....*...
gi 1237938158  90 TFAYVCYR 97
Cdd:cd03396   188 LIALLLYR 195
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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