NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1012306331|ref|NP_001308685|]
View 

CDAN1-interacting nuclease 1 isoform 2 [Homo sapiens]

Protein Classification

C15orf41 family protein( domain architecture ID 10632347)

C15orf41 family protein is a TPD sequence-motif-containing protein, similar to human C15orf41 protein that plays a role in erythroid cell differentiation and is associated with congenital dyserythropoietic anemia

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TPD pfam14811
Protein of unknown function TPD sequence-motif; This is a family of eukaryotic proteins of ...
 34-171 5.67e-84

Protein of unknown function TPD sequence-motif; This is a family of eukaryotic proteins of unknown function. A few members have an associated zinc-finger domain. All members carry a highly conserved TPD sequence-motif.


:

Pssm-ID: 464328  Cd Length: 138  Bit Score: 244.01  E-value: 5.67e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012306331  34 PDGVLANQVYQCIVNDCCYGPLVDCIKHAIGHEHEVLLRDLLLEKNLSFLDEDQLRAKGYDKTPDFILQVPVAVEGHIIH 113
Cdd:pfam14811   1 EDKRLAAEVRQCIEYDDFYSPIADAIRHSIGQEYEDLLEKWLKERGIPFQTEDDLRAKGYDKTPDIKLEVPIAVDGHVVN 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1012306331 114 WIESKASFGDECSHHAYLHDQFWSYWNRFGPGLVIYWYGFIQELDCNRERGILLKACF 171
Cdd:pfam14811  81 WIESKASFGDEIEHKKYLKDQLSSYWNRFGPGMVIYWFGYLDELSLPADKGILIKDRF 138
 
Name Accession Description Interval E-value
TPD pfam14811
Protein of unknown function TPD sequence-motif; This is a family of eukaryotic proteins of ...
 34-171 5.67e-84

Protein of unknown function TPD sequence-motif; This is a family of eukaryotic proteins of unknown function. A few members have an associated zinc-finger domain. All members carry a highly conserved TPD sequence-motif.


Pssm-ID: 464328  Cd Length: 138  Bit Score: 244.01  E-value: 5.67e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012306331  34 PDGVLANQVYQCIVNDCCYGPLVDCIKHAIGHEHEVLLRDLLLEKNLSFLDEDQLRAKGYDKTPDFILQVPVAVEGHIIH 113
Cdd:pfam14811   1 EDKRLAAEVRQCIEYDDFYSPIADAIRHSIGQEYEDLLEKWLKERGIPFQTEDDLRAKGYDKTPDIKLEVPIAVDGHVVN 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1012306331 114 WIESKASFGDECSHHAYLHDQFWSYWNRFGPGLVIYWYGFIQELDCNRERGILLKACF 171
Cdd:pfam14811  81 WIESKASFGDEIEHKKYLKDQLSSYWNRFGPGMVIYWFGYLDELSLPADKGILIKDRF 138
 
Name Accession Description Interval E-value
TPD pfam14811
Protein of unknown function TPD sequence-motif; This is a family of eukaryotic proteins of ...
 34-171 5.67e-84

Protein of unknown function TPD sequence-motif; This is a family of eukaryotic proteins of unknown function. A few members have an associated zinc-finger domain. All members carry a highly conserved TPD sequence-motif.


Pssm-ID: 464328  Cd Length: 138  Bit Score: 244.01  E-value: 5.67e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012306331  34 PDGVLANQVYQCIVNDCCYGPLVDCIKHAIGHEHEVLLRDLLLEKNLSFLDEDQLRAKGYDKTPDFILQVPVAVEGHIIH 113
Cdd:pfam14811   1 EDKRLAAEVRQCIEYDDFYSPIADAIRHSIGQEYEDLLEKWLKERGIPFQTEDDLRAKGYDKTPDIKLEVPIAVDGHVVN 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1012306331 114 WIESKASFGDECSHHAYLHDQFWSYWNRFGPGLVIYWYGFIQELDCNRERGILLKACF 171
Cdd:pfam14811  81 WIESKASFGDEIEHKKYLKDQLSSYWNRFGPGMVIYWFGYLDELSLPADKGILIKDRF 138
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH