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Conserved domains on  [gi|987437845|ref|NP_001306924|]
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PCNA-interacting partner isoform 4 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
UvrD super family cl33806
Superfamily I DNA or RNA helicase [Replication, recombination and repair];
91-140 2.22e-06

Superfamily I DNA or RNA helicase [Replication, recombination and repair];


The actual alignment was detected with superfamily member COG0210:

Pssm-ID: 439980 [Multi-domain]  Cd Length: 721  Bit Score: 46.47  E-value: 2.22e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 987437845  91 KIIFSYLNLLVNSKNDLAVAYILNIPDRGLGREAFTDLKHAAREKQMSIF 140
Cdd:COG0210  388 KDLLAYLRLLANPDDDVALLRILNVPRRGIGAATLERLREAAREEGISLL 437
 
Name Accession Description Interval E-value
UvrD COG0210
Superfamily I DNA or RNA helicase [Replication, recombination and repair];
91-140 2.22e-06

Superfamily I DNA or RNA helicase [Replication, recombination and repair];


Pssm-ID: 439980 [Multi-domain]  Cd Length: 721  Bit Score: 46.47  E-value: 2.22e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 987437845  91 KIIFSYLNLLVNSKNDLAVAYILNIPDRGLGREAFTDLKHAAREKQMSIF 140
Cdd:COG0210  388 KDLLAYLRLLANPDDDVALLRILNVPRRGIGAATLERLREAAREEGISLL 437
UvrD_C pfam13361
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ...
91-160 1.71e-03

UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.


Pssm-ID: 433145 [Multi-domain]  Cd Length: 377  Bit Score: 37.77  E-value: 1.71e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987437845   91 KIIFSYLNLLVNSKNDLAVAYILNIPDRGLGREAFTDLkhaareKQMSIFLVWLCDMFKIKTPCTVDPCI 160
Cdd:pfam13361 117 KDILAYLRLIANKHDSISLKRILNGPKRGIGNATLERI------REYKKRGLRLSDFINPDTLTYGDPFV 180
 
Name Accession Description Interval E-value
UvrD COG0210
Superfamily I DNA or RNA helicase [Replication, recombination and repair];
91-140 2.22e-06

Superfamily I DNA or RNA helicase [Replication, recombination and repair];


Pssm-ID: 439980 [Multi-domain]  Cd Length: 721  Bit Score: 46.47  E-value: 2.22e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 987437845  91 KIIFSYLNLLVNSKNDLAVAYILNIPDRGLGREAFTDLKHAAREKQMSIF 140
Cdd:COG0210  388 KDLLAYLRLLANPDDDVALLRILNVPRRGIGAATLERLREAAREEGISLL 437
UvrD_C pfam13361
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ...
91-160 1.71e-03

UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.


Pssm-ID: 433145 [Multi-domain]  Cd Length: 377  Bit Score: 37.77  E-value: 1.71e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987437845   91 KIIFSYLNLLVNSKNDLAVAYILNIPDRGLGREAFTDLkhaareKQMSIFLVWLCDMFKIKTPCTVDPCI 160
Cdd:pfam13361 117 KDILAYLRLIANKHDSISLKRILNGPKRGIGNATLERI------REYKKRGLRLSDFINPDTLTYGDPFV 180
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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