|
Name |
Accession |
Description |
Interval |
E-value |
| SM-ATX |
pfam14438 |
Ataxin 2 SM domain; This SM domain is found in Ataxin-2. |
3-76 |
4.26e-21 |
|
Ataxin 2 SM domain; This SM domain is found in Ataxin-2.
:
Pssm-ID: 464173 Cd Length: 78 Bit Score: 88.38 E-value: 4.26e-21
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 858437822 3 MVHILTSVVGSKCEVQVKNGGIYEGVFKTYSP--KCDLVLDAAHEKSTESSSG--PKREEIMESILFKCSDFVVVQFK 76
Cdd:pfam14438 1 LLFLLTSLVGLVVEVTTKNGEVYEGIFSTASLekDFGVVLKMARRIKKSNGSGlnPVRGEIVDTMIFPAKDIVDIEAK 78
|
|
| LsmAD |
pfam06741 |
LsmAD domain; This domain is found associated with Lsm domain. |
144-205 |
8.07e-16 |
|
LsmAD domain; This domain is found associated with Lsm domain.
:
Pssm-ID: 461998 [Multi-domain] Cd Length: 65 Bit Score: 72.60 E-value: 8.07e-16
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 858437822 144 YGVVSTYDSSLssYTVPLERdNSEEFLKREARANQLAEEIESSAQYKARVALENDDR------SEEEK 205
Cdd:pfam06741 1 FGVKSTYDENL--YTTKLDR-SSPDYKEREAEAERIAREIEGSASTNAHVAEERGLDvddsglDEEDK 65
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
664-988 |
5.29e-08 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 57.64 E-value: 5.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 664 PKPSTTPTSPRPQAQPSP--SMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQ------PLYPIPMTPMPVNQAKTYRAV 735
Cdd:PHA03247 2674 AQASSPPQRPRRRAARPTvgSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAaarqasPALPAAPAPPAVPAGPATPGG 2753
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 736 PNMPQQRQDQHHQSAMMHPAS-AAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPhyqSQHPHVYSPVIQGNARMMAP 814
Cdd:PHA03247 2754 PARPARPPTTAGPPAPAPPAApAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAA---VLAPAAALPPAASPAGPLPP 2830
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 815 PTHAQP-------GLVSSSATQYGA------------HEQTHAMYACP-KLPYNKETSPSFyfAISTGSLAQQyahPNAT 874
Cdd:PHA03247 2831 PTSAQPtapppppGPPPPSLPLGGSvapggdvrrrppSRSPAAKPAAPaRPPVRRLARPAV--SRSTESFALP---PDQP 2905
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 875 LHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSfp 954
Cdd:PHA03247 2906 ERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPA-- 2983
|
330 340 350
....*....|....*....|....*....|....*
gi 858437822 955 aaqqtvftihPSHVQPA-YTNPPHMAHVPQCASEA 988
Cdd:PHA03247 2984 ----------PSREAPAsSTPPLTGHSLSRVSSWA 3008
|
|
| PRK12323 super family |
cl46901 |
DNA polymerase III subunit gamma/tau; |
303-494 |
7.82e-04 |
|
DNA polymerase III subunit gamma/tau;
The actual alignment was detected with superfamily member PRK12323:
Pssm-ID: 481241 [Multi-domain] Cd Length: 700 Bit Score: 43.33 E-value: 7.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 303 QSGPNSLPPRAAT----PTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSI 378
Cdd:PRK12323 367 QSGGGAGPATAAAapvaQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGG 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 379 SSGLEFVSHNPPSEAATPPVARTSPSGGTWSSV-VSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAM 457
Cdd:PRK12323 447 APAPAPAPAAAPAAAARPAAAGPRPVAAAAAAApARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESI 526
|
170 180 190
....*....|....*....|....*....|....*..
gi 858437822 458 PIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSP 494
Cdd:PRK12323 527 PDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAP 563
|
|
| PAM2 |
pfam07145 |
Ataxin-2 C-terminal region; The PABP-interacting motif PAM2 has been identified in various ... |
645-660 |
5.40e-03 |
|
Ataxin-2 C-terminal region; The PABP-interacting motif PAM2 has been identified in various eukaryotic proteins as an important binding site for pfam00658. It has been found in a wide range of eukaryotic proteins. Strikingly, this motif appears to occur solely outside of globular domains.
:
Pssm-ID: 429316 Cd Length: 17 Bit Score: 35.28 E-value: 5.40e-03
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SM-ATX |
pfam14438 |
Ataxin 2 SM domain; This SM domain is found in Ataxin-2. |
3-76 |
4.26e-21 |
|
Ataxin 2 SM domain; This SM domain is found in Ataxin-2.
Pssm-ID: 464173 Cd Length: 78 Bit Score: 88.38 E-value: 4.26e-21
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 858437822 3 MVHILTSVVGSKCEVQVKNGGIYEGVFKTYSP--KCDLVLDAAHEKSTESSSG--PKREEIMESILFKCSDFVVVQFK 76
Cdd:pfam14438 1 LLFLLTSLVGLVVEVTTKNGEVYEGIFSTASLekDFGVVLKMARRIKKSNGSGlnPVRGEIVDTMIFPAKDIVDIEAK 78
|
|
| LsmAD |
pfam06741 |
LsmAD domain; This domain is found associated with Lsm domain. |
144-205 |
8.07e-16 |
|
LsmAD domain; This domain is found associated with Lsm domain.
Pssm-ID: 461998 [Multi-domain] Cd Length: 65 Bit Score: 72.60 E-value: 8.07e-16
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 858437822 144 YGVVSTYDSSLssYTVPLERdNSEEFLKREARANQLAEEIESSAQYKARVALENDDR------SEEEK 205
Cdd:pfam06741 1 FGVKSTYDENL--YTTKLDR-SSPDYKEREAEAERIAREIEGSASTNAHVAEERGLDvddsglDEEDK 65
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
664-988 |
5.29e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 57.64 E-value: 5.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 664 PKPSTTPTSPRPQAQPSP--SMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQ------PLYPIPMTPMPVNQAKTYRAV 735
Cdd:PHA03247 2674 AQASSPPQRPRRRAARPTvgSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAaarqasPALPAAPAPPAVPAGPATPGG 2753
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 736 PNMPQQRQDQHHQSAMMHPAS-AAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPhyqSQHPHVYSPVIQGNARMMAP 814
Cdd:PHA03247 2754 PARPARPPTTAGPPAPAPPAApAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAA---VLAPAAALPPAASPAGPLPP 2830
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 815 PTHAQP-------GLVSSSATQYGA------------HEQTHAMYACP-KLPYNKETSPSFyfAISTGSLAQQyahPNAT 874
Cdd:PHA03247 2831 PTSAQPtapppppGPPPPSLPLGGSvapggdvrrrppSRSPAAKPAAPaRPPVRRLARPAV--SRSTESFALP---PDQP 2905
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 875 LHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSfp 954
Cdd:PHA03247 2906 ERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPA-- 2983
|
330 340 350
....*....|....*....|....*....|....*
gi 858437822 955 aaqqtvftihPSHVQPA-YTNPPHMAHVPQCASEA 988
Cdd:PHA03247 2984 ----------PSREAPAsSTPPLTGHSLSRVSSWA 3008
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
665-837 |
8.47e-06 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 50.03 E-value: 8.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 665 KPSTTPTSPRPQAQPSPSMVGHQ--------------QPTPVYTQPvcfaPNMMYPVPVSPGVQPLYPIPMTPMPVNQAK 730
Cdd:pfam09770 169 KAAAPAPAPQPAAQPASLPAPSRkmmsleeveaamraQAKKPAQQP----APAPAQPPAAPPAQQAQQQQQFPPQIQQQQ 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 731 TYRAVPNMPQQRQDQHHQ-SAMMHPASAAGPPiaaTPPAYSTQyvaySPQQFPNQPLVQHVPHYQSQHPHVYSPV---IQ 806
Cdd:pfam09770 245 QPQQQPQQPQQHPGQGHPvTILQRPQSPQPDP---AQPSIQPQ----AQQFHQQPPPVPVQPTQILQNPNRLSAArvgYP 317
|
170 180 190
....*....|....*....|....*....|.
gi 858437822 807 GNARMMAPPTHAQPGLVSSSATQYGAHEQTH 837
Cdd:pfam09770 318 QNPQPGVQPAPAHQAHRQQGSFGRQAPIITH 348
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
672-785 |
4.66e-05 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 47.49 E-value: 4.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 672 SPRPQAQPSPS-MVGHQQPTPVYTQpvcfAPNMMYP-VPVSPGVQPLYPIPMTPMPVNQAKTYravPNMPQQRQDQHHQS 749
Cdd:TIGR01628 379 QPRMRQLPMGSpMGGAMGQPPYYGQ----GPQQQFNgQPLGWPRMSMMPTPMGPGGPLRPNGL---APMNAVRAPSRNAQ 451
|
90 100 110
....*....|....*....|....*....|....*.
gi 858437822 750 AMMHPASAagPPIAATPPAYSTQyvaySPQQFPNQP 785
Cdd:TIGR01628 452 NAAQKPPM--QPVMYPPNYQSLP----LSQDLPQPQ 481
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
303-494 |
7.82e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 43.33 E-value: 7.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 303 QSGPNSLPPRAAT----PTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSI 378
Cdd:PRK12323 367 QSGGGAGPATAAAapvaQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGG 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 379 SSGLEFVSHNPPSEAATPPVARTSPSGGTWSSV-VSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAM 457
Cdd:PRK12323 447 APAPAPAPAAAPAAAARPAAAGPRPVAAAAAAApARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESI 526
|
170 180 190
....*....|....*....|....*....|....*..
gi 858437822 458 PIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSP 494
Cdd:PRK12323 527 PDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAP 563
|
|
| PAM2 |
pfam07145 |
Ataxin-2 C-terminal region; The PABP-interacting motif PAM2 has been identified in various ... |
645-660 |
5.40e-03 |
|
Ataxin-2 C-terminal region; The PABP-interacting motif PAM2 has been identified in various eukaryotic proteins as an important binding site for pfam00658. It has been found in a wide range of eukaryotic proteins. Strikingly, this motif appears to occur solely outside of globular domains.
Pssm-ID: 429316 Cd Length: 17 Bit Score: 35.28 E-value: 5.40e-03
|
| Sm_like |
cd00600 |
Sm and related proteins; The eukaryotic Sm and Sm-like (LSm) proteins associate with RNA to ... |
7-74 |
7.57e-03 |
|
Sm and related proteins; The eukaryotic Sm and Sm-like (LSm) proteins associate with RNA to form the core domain of the ribonucleoprotein particles involved in a variety of RNA processing events including pre-mRNA splicing, telomere replication, and mRNA degradation. Members of this family share a highly conserved Sm fold containing an N-terminal helix followed by a strongly bent five-stranded antiparallel beta-sheet. Sm-like proteins exist in archaea as well as prokaryotes that form heptameric and hexameric ring structures similar to those found in eukaryotes.
Pssm-ID: 212462 [Multi-domain] Cd Length: 63 Bit Score: 36.07 E-value: 7.57e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 858437822 7 LTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTEsssgpKREEIMESILFKCSDFVVVQ 74
Cdd:cd00600 1 LKDFIGKTVSVELKDGRVLTGTLVAFDKYMNLVLDDVVETGRD-----GKVRVLGLVLIRGSNIVSIR 63
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SM-ATX |
pfam14438 |
Ataxin 2 SM domain; This SM domain is found in Ataxin-2. |
3-76 |
4.26e-21 |
|
Ataxin 2 SM domain; This SM domain is found in Ataxin-2.
Pssm-ID: 464173 Cd Length: 78 Bit Score: 88.38 E-value: 4.26e-21
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 858437822 3 MVHILTSVVGSKCEVQVKNGGIYEGVFKTYSP--KCDLVLDAAHEKSTESSSG--PKREEIMESILFKCSDFVVVQFK 76
Cdd:pfam14438 1 LLFLLTSLVGLVVEVTTKNGEVYEGIFSTASLekDFGVVLKMARRIKKSNGSGlnPVRGEIVDTMIFPAKDIVDIEAK 78
|
|
| LsmAD |
pfam06741 |
LsmAD domain; This domain is found associated with Lsm domain. |
144-205 |
8.07e-16 |
|
LsmAD domain; This domain is found associated with Lsm domain.
Pssm-ID: 461998 [Multi-domain] Cd Length: 65 Bit Score: 72.60 E-value: 8.07e-16
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 858437822 144 YGVVSTYDSSLssYTVPLERdNSEEFLKREARANQLAEEIESSAQYKARVALENDDR------SEEEK 205
Cdd:pfam06741 1 FGVKSTYDENL--YTTKLDR-SSPDYKEREAEAERIAREIEGSASTNAHVAEERGLDvddsglDEEDK 65
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
664-988 |
5.29e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 57.64 E-value: 5.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 664 PKPSTTPTSPRPQAQPSP--SMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQ------PLYPIPMTPMPVNQAKTYRAV 735
Cdd:PHA03247 2674 AQASSPPQRPRRRAARPTvgSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAaarqasPALPAAPAPPAVPAGPATPGG 2753
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 736 PNMPQQRQDQHHQSAMMHPAS-AAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPhyqSQHPHVYSPVIQGNARMMAP 814
Cdd:PHA03247 2754 PARPARPPTTAGPPAPAPPAApAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAA---VLAPAAALPPAASPAGPLPP 2830
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 815 PTHAQP-------GLVSSSATQYGA------------HEQTHAMYACP-KLPYNKETSPSFyfAISTGSLAQQyahPNAT 874
Cdd:PHA03247 2831 PTSAQPtapppppGPPPPSLPLGGSvapggdvrrrppSRSPAAKPAAPaRPPVRRLARPAV--SRSTESFALP---PDQP 2905
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 875 LHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSfp 954
Cdd:PHA03247 2906 ERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPA-- 2983
|
330 340 350
....*....|....*....|....*....|....*
gi 858437822 955 aaqqtvftihPSHVQPA-YTNPPHMAHVPQCASEA 988
Cdd:PHA03247 2984 ----------PSREAPAsSTPPLTGHSLSRVSSWA 3008
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
665-837 |
8.47e-06 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 50.03 E-value: 8.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 665 KPSTTPTSPRPQAQPSPSMVGHQ--------------QPTPVYTQPvcfaPNMMYPVPVSPGVQPLYPIPMTPMPVNQAK 730
Cdd:pfam09770 169 KAAAPAPAPQPAAQPASLPAPSRkmmsleeveaamraQAKKPAQQP----APAPAQPPAAPPAQQAQQQQQFPPQIQQQQ 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 731 TYRAVPNMPQQRQDQHHQ-SAMMHPASAAGPPiaaTPPAYSTQyvaySPQQFPNQPLVQHVPHYQSQHPHVYSPV---IQ 806
Cdd:pfam09770 245 QPQQQPQQPQQHPGQGHPvTILQRPQSPQPDP---AQPSIQPQ----AQQFHQQPPPVPVQPTQILQNPNRLSAArvgYP 317
|
170 180 190
....*....|....*....|....*....|.
gi 858437822 807 GNARMMAPPTHAQPGLVSSSATQYGAHEQTH 837
Cdd:pfam09770 318 QNPQPGVQPAPAHQAHRQQGSFGRQAPIITH 348
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
672-785 |
4.66e-05 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 47.49 E-value: 4.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 672 SPRPQAQPSPS-MVGHQQPTPVYTQpvcfAPNMMYP-VPVSPGVQPLYPIPMTPMPVNQAKTYravPNMPQQRQDQHHQS 749
Cdd:TIGR01628 379 QPRMRQLPMGSpMGGAMGQPPYYGQ----GPQQQFNgQPLGWPRMSMMPTPMGPGGPLRPNGL---APMNAVRAPSRNAQ 451
|
90 100 110
....*....|....*....|....*....|....*.
gi 858437822 750 AMMHPASAagPPIAATPPAYSTQyvaySPQQFPNQP 785
Cdd:TIGR01628 452 NAAQKPPM--QPVMYPPNYQSLP----LSQDLPQPQ 481
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
662-950 |
5.23e-05 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 47.39 E-value: 5.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 662 SQPKPSTTPTSPRPQAQPSPsmvGHQQPTPVYT-QPVCFAPNMMYPVPVSPGVQPLYPiPMTPMPVNQAKTYRAVPNMPQ 740
Cdd:PRK10263 345 PVASVDVPPAQPTVAWQPVP---GPQTGEPVIApAPEGYPQQSQYAQPAVQYNEPLQQ-PVQPQQPYYAPAAEQPAQQPY 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 741 QRQDQHHQSAMMHPASAAGPPIAATPpaystqyvaysPQQFPNQPLVQHVPHYQSQHPHVySPVIQgnarmmaPPTHAQP 820
Cdd:PRK10263 421 YAPAPEQPAQQPYYAPAPEQPVAGNA-----------WQAEEQQSTFAPQSTYQTEQTYQ-QPAAQ-------EPLYQQP 481
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 821 GLVsssatqygahEQTHAMYACPKLPYNKETSPSFYFaisTGSLAQQYAHPNATLHP-HTPHPQPSATPTGQQQSQHGGS 899
Cdd:PRK10263 482 QPV----------EQQPVVEPEPVVEETKPARPPLYY---FEEVEEKRAREREQLAAwYQPIPEPVKEPEPIKSSLKAPS 548
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 858437822 900 HPAPSPVQHHQHQAAQALHLaspqqQSAIYHAGLAPTP--PSMTPASN-TQSPQ 950
Cdd:PRK10263 549 VAAVPPVEAAAAVSPLASGV-----KKATLATGAAATVaaPVFSLANSgGPRPQ 597
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
665-1069 |
1.04e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.86 E-value: 1.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 665 KPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQd 744
Cdd:PHA03247 2588 RPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRR- 2666
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 745 qhhQSAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPglvs 824
Cdd:PHA03247 2667 ---ARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAP---- 2739
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 825 ssatqygaheqthamyaCPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPS 904
Cdd:PHA03247 2740 -----------------APPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPW 2802
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 905 PVQHHQHQAAQALHLASPQQQSaiyhAGLAPTPPSMTPASnTQSPQNSFPAAQQTVFTIHP----SHVQPAYTNPPHMAH 980
Cdd:PHA03247 2803 DPADPPAAVLAPAAALPPAASP----AGPLPPPTSAQPTA-PPPPPGPPPPSLPLGGSVAPggdvRRRPPSRSPAAKPAA 2877
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 981 VPQCASEALARCGLEMRLSWIYLSEGYLAHVQSGMVPSHPTAHAPMMLMTTQPPGGPQAALAQSALQPIPVSTTAHFPYM 1060
Cdd:PHA03247 2878 PARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSG 2957
|
....*....
gi 858437822 1061 THPSVQAHH 1069
Cdd:PHA03247 2958 AVPQPWLGA 2966
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
663-903 |
1.37e-04 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 46.18 E-value: 1.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 663 QPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFA-PNMMYPVPVSP--------GVQPLYPIPMTPMPVNQAKTYR 733
Cdd:pfam09770 106 QPAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRTGyEKYKEPEPIPDlqvdaslwGVAPKKAAAPAPAPQPAAQPAS 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 734 AVPNMPQQRQDQHHQSAMM---HPASAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPhvysPVIQGNAR 810
Cdd:pfam09770 186 LPAPSRKMMSLEEVEAAMRaqaKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQP----QQHPGQGH 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 811 MMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPynketSPSfyfaistgslaQQYAHPN------ATLHPHTPHPQP 884
Cdd:pfam09770 262 PVTILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPV-----QPT-----------QILQNPNrlsaarVGYPQNPQPGVQ 325
|
250
....*....|....*....
gi 858437822 885 SATPTGQQQSQHGGSHPAP 903
Cdd:pfam09770 326 PAPAHQAHRQQGSFGRQAP 344
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
647-930 |
1.68e-04 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 45.83 E-value: 1.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 647 STLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVytQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPV 726
Cdd:PHA03378 583 SQLASSAPSYAQTPWPVPHPSQTPEPPTTQSHIPETSAPRQWPMPL--RPIPMRPLRMQPITFNVLVFPTPHQPPQVEIT 660
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 727 NQAKTYRAVPNMPQQRQDQHHqsAMMHPASAAgPPIAATPPAYSTQYvaySPQQFPNQPlvqhvphyqSQHPHvyspviq 806
Cdd:PHA03378 661 PYKPTWTQIGHIPYQPSPTGA--NTMLPIQWA-PGTMQPPPRAPTPM---RPPAAPPGR---------AQRPA------- 718
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 807 gNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETspsfyfaistgslaqQYAHPNATLHPHTPHPQPSA 886
Cdd:PHA03378 719 -AATGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPG---------------RARPPAAAPGAPTPQPPPQA 782
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 858437822 887 TPTGQQQSQHGgshPAPSPVQHHQHQAAQALHLASPQQQSAIYH 930
Cdd:PHA03378 783 PPAPQQRPRGA---PTPQPPPQAGPTSMQLMPRAAPGQQGPTKQ 823
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
645-801 |
4.62e-04 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 44.03 E-value: 4.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 645 RKSTLNpnaKEFNPRSFSQPKPSTTptSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQ--PLYPIPMT 722
Cdd:TIGR01628 367 RRAHLQ---DQFMQLQPRMRQLPMG--SPMGGAMGQPPYYGQGPQQQFNGQPLGWPRMSMMPTPMGPGGPlrPNGLAPMN 441
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 723 PMpvnqaktyRAVPNMPQQRQDQHHQSAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQ------ 796
Cdd:TIGR01628 442 AV--------RAPSRNAQNAAQKPPMQPVMYPPNYQSLPLSQDLPQPQSTASQGGQNKKLAQVLASATPQMQKQvlgerl 513
|
....*
gi 858437822 797 HPHVY 801
Cdd:TIGR01628 514 FPLVE 518
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
303-494 |
7.82e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 43.33 E-value: 7.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 303 QSGPNSLPPRAAT----PTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSI 378
Cdd:PRK12323 367 QSGGGAGPATAAAapvaQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGG 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 379 SSGLEFVSHNPPSEAATPPVARTSPSGGTWSSV-VSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAM 457
Cdd:PRK12323 447 APAPAPAPAAAPAAAARPAAAGPRPVAAAAAAApARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESI 526
|
170 180 190
....*....|....*....|....*....|....*..
gi 858437822 458 PIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSP 494
Cdd:PRK12323 527 PDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAP 563
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
753-983 |
8.05e-04 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 43.49 E-value: 8.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 753 HPASAAGPPIAATPPAYSTQY-VAYSPQQFPNQPLVQHVPHYQSQHP----HVySPVIQGNARMMAPPTHAQPGLVSSSA 827
Cdd:pfam09770 106 QPAARAAQSSAQPPASSLPQYqYASQQSQQPSKPVRTGYEKYKEPEPipdlQV-DASLWGVAPKKAAAPAPAPQPAAQPA 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 828 TQYGAH-------EQTHAMYACPKLPYNKETSPSFYFAistgslaQQYAHPNATLHPHTPHPQPSATPTGQQQSQHGGSH 900
Cdd:pfam09770 185 SLPAPSrkmmsleEVEAAMRAQAKKPAQQPAPAPAQPP-------AAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHP 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 901 PAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPqNSFPAAQQTVFTIHPSHVQPAytnPPHMAH 980
Cdd:pfam09770 258 GQGHPVTILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNP-NRLSAARVGYPQNPQPGVQPA---PAHQAH 333
|
...
gi 858437822 981 VPQ 983
Cdd:pfam09770 334 RQQ 336
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
306-906 |
1.15e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 43.39 E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 306 PNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPV-STMPK--RMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGL 382
Cdd:PHA03247 2556 PPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPqSARPRapVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAA 2635
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 383 EFVSHNPPSEAATPPVARTSPSGGTWS-----SVVSGVPRLSPKTHRPRSPRQNSigntPSGPV--LASPQAGIIPTEAV 455
Cdd:PHA03247 2636 NEPDPHPPPTVPPPERPRDDPAPGRVSrprraRRLGRAAQASSPPQRPRRRAARP----TVGSLtsLADPPPPPPTPEPA 2711
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 456 AMPIPAASPTPASPASNRAVTPSSEAKD-SRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGisPVVSEHRKQIddlkk 534
Cdd:PHA03247 2712 PHALVSATPLPPGPAAARQASPALPAAPaPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAA--PAAGPPRRLT----- 2784
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 535 fkndfRLQPSSTSESMDQLlnknregeksrdlikdkiePSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPE 614
Cdd:PHA03247 2785 -----RPAVASLSESRESL-------------------PSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPP 2840
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 615 VTSQGVQTSSPACkqekddkeekkdaaeqvrkSTLNPNAkEFNPRSFSQPKPSTTPTSPRPQ----AQPSPSmvghqQPT 690
Cdd:PHA03247 2841 PPPGPPPPSLPLG-------------------GSVAPGG-DVRRRPPSRSPAAKPAAPARPPvrrlARPAVS-----RST 2895
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 691 PVYTQPvcfapnmmyPVPVSPGVQPLYPIPMTPMPVNQAKTYRAVPNMPQQRQDqhhqsammhpasAAGPPIAATPPAYS 770
Cdd:PHA03247 2896 ESFALP---------PDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQ------------PPLAPTTDPAGAGE 2954
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 771 TQYVAYSPQQFPNQPLVQHVPHYQSQHPhvySPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPK----LP 846
Cdd:PHA03247 2955 PSGAVPQPWLGALVPGRVAVPRFRVPQP---APSREAPASSTPPLTGHSLSRVSSWASSLALHEETDPPPVSLKqtlwPP 3031
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 858437822 847 YNKETSPSFYFAISTGSLAQQYA---HPNATLHPHTPHPQPSATPTGQQQSQHggSHPAPSPV 906
Cdd:PHA03247 3032 DDTEDSDADSLFDSDSERSDLEAldpLPPEPHDPFAHEPDPATPEAGARESPS--SQFGPPPL 3092
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
651-976 |
3.00e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 41.68 E-value: 3.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 651 PNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYP-------VPVSPGVQPLYPIPMTP 723
Cdd:pfam03154 184 PSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPqrlpsphPPLQPMTQPPPPSQVSP 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 724 MPVNQAKTYRAVPNMPQQRQDQhhQSAMMHPASAAGPPIAAT------PPAYSTQyVAYSPQQFPNQPLVQhvPHYQSQH 797
Cdd:pfam03154 264 QPLPQPSLHGQMPPMPHSLQTG--PSHMQHPVPPQPFPLTPQssqsqvPPGPSPA-APGQSQQRIHTPPSQ--SQLQSQQ 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 798 PHVYSPVIQGNARM---MAPPTHAQPGLVSSSATQYGAHEQTHAMYacpKLPYNKETSPSFYFAISTGSLAQQYAHPNA- 873
Cdd:pfam03154 339 PPREQPLPPAPLSMphiKPPPTTPIPQLPNPQSHKHPPHLSGPSPF---QMNSNLPPPPALKPLSSLSTHHPPSAHPPPl 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 874 TLHPHT-PHPQPSATPTGQQQSQH----GGSHPAPSPVQHHQHQAAQALHLASPQQQSAIyhaglapTPPSMTPASNTQS 948
Cdd:pfam03154 416 QLMPQSqQLPPPPAQPPVLTQSQSlpppAASHPPTSGLHQVPSQSPFPQHPFVPGGPPPI-------TPPSGPPTSTSSA 488
|
330 340
....*....|....*....|....*...
gi 858437822 949 PQNSFPAAQQTVFTIHPSHVQPAYTNPP 976
Cdd:pfam03154 489 MPGIQPPSSASVSSSGPVPAAVSCPLPP 516
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
658-1055 |
3.04e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 41.51 E-value: 3.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 658 PRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPvytqpvcfAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAVPN 737
Cdd:PRK07764 400 SAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAP--------APAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPA 471
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 738 MPQQRQDQHHQSAMMHPASAAGPPIAATPPAYSTQYVAYSPQQFPNQpLVQHVPHYQ-------SQHPHVYSpvIQGNAR 810
Cdd:PRK07764 472 AAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRERWPE-ILAAVPKRSrktwailLPEATVLG--VRGDTL 548
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 811 MMApptHAQPGLVSSSATQYGA-------HEQTHAMYAcpklpYNKETSPSFYFAISTGSLAQQYAHPNatlhPHTPHPQ 883
Cdd:PRK07764 549 VLG---FSTGGLARRFASPGNAevlvtalAEELGGDWQ-----VEAVVGPAPGAAGGEGPPAPASSGPP----EEAARPA 616
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 884 PSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFTI 963
Cdd:PRK07764 617 APAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGA 696
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 858437822 964 HPSHVQPAYTNPPHMAHVPQCASEALARCGlemrlswiylSEGYLAHVQSGMVPSHPTAHAPMMLMTT--QPPGGPQAAL 1041
Cdd:PRK07764 697 APAQPAPAPAATPPAGQADDPAAQPPQAAQ----------GASAPSPAADDPVPLPPEPDDPPDPAGApaQPPPPPAPAP 766
|
410
....*....|....
gi 858437822 1042 AQSALQPIPVSTTA 1055
Cdd:PRK07764 767 AAAPAAAPPPSPPS 780
|
|
| PAM2 |
pfam07145 |
Ataxin-2 C-terminal region; The PABP-interacting motif PAM2 has been identified in various ... |
645-660 |
5.40e-03 |
|
Ataxin-2 C-terminal region; The PABP-interacting motif PAM2 has been identified in various eukaryotic proteins as an important binding site for pfam00658. It has been found in a wide range of eukaryotic proteins. Strikingly, this motif appears to occur solely outside of globular domains.
Pssm-ID: 429316 Cd Length: 17 Bit Score: 35.28 E-value: 5.40e-03
|
| Sm_like |
cd00600 |
Sm and related proteins; The eukaryotic Sm and Sm-like (LSm) proteins associate with RNA to ... |
7-74 |
7.57e-03 |
|
Sm and related proteins; The eukaryotic Sm and Sm-like (LSm) proteins associate with RNA to form the core domain of the ribonucleoprotein particles involved in a variety of RNA processing events including pre-mRNA splicing, telomere replication, and mRNA degradation. Members of this family share a highly conserved Sm fold containing an N-terminal helix followed by a strongly bent five-stranded antiparallel beta-sheet. Sm-like proteins exist in archaea as well as prokaryotes that form heptameric and hexameric ring structures similar to those found in eukaryotes.
Pssm-ID: 212462 [Multi-domain] Cd Length: 63 Bit Score: 36.07 E-value: 7.57e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 858437822 7 LTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTEsssgpKREEIMESILFKCSDFVVVQ 74
Cdd:cd00600 1 LKDFIGKTVSVELKDGRVLTGTLVAFDKYMNLVLDDVVETGRD-----GKVRVLGLVLIRGSNIVSIR 63
|
|
| |
