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Conserved domains on  [gi|819231783|ref|NP_001295415|]
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threonylcarbamoyladenosine tRNA methylthiotransferase isoform 2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UPF0004 super family cl38018
Uncharacterized protein family UPF0004; This family is the N terminal half of the Prosite ...
 64-94 1.19e-07

Uncharacterized protein family UPF0004; This family is the N terminal half of the Prosite family. The C-terminal half has been shown to be related to MiaB proteins. This domain is a nearly always found in conjunction with pfam04055 and pfam01938 although its function is uncertain.


The actual alignment was detected with superfamily member pfam00919:

Pssm-ID: 459997 [Multi-domain]  Cd Length: 98  Bit Score: 46.35  E-value: 1.19e-07
                          10        20        30
                  ....*....|....*....|....*....|.
gi 819231783   64 KIWIRTWGCSHNNSDGEYMAGQLAAYGYKIT 94
Cdd:pfam00919   1 KVYIETLGCQMNQADSEIMAGLLEKAGYEVV 31
 
Name Accession Description Interval E-value
UPF0004 pfam00919
Uncharacterized protein family UPF0004; This family is the N terminal half of the Prosite ...
 64-94 1.19e-07

Uncharacterized protein family UPF0004; This family is the N terminal half of the Prosite family. The C-terminal half has been shown to be related to MiaB proteins. This domain is a nearly always found in conjunction with pfam04055 and pfam01938 although its function is uncertain.


Pssm-ID: 459997 [Multi-domain]  Cd Length: 98  Bit Score: 46.35  E-value: 1.19e-07
                          10        20        30
                  ....*....|....*....|....*....|.
gi 819231783   64 KIWIRTWGCSHNNSDGEYMAGQLAAYGYKIT 94
Cdd:pfam00919   1 KVYIETLGCQMNQADSEIMAGLLEKAGYEVV 31
MiaB COG0621
tRNA A37 methylthiotransferase MiaB [Translation, ribosomal structure and biogenesis]; tRNA ...
 64-95 8.15e-06

tRNA A37 methylthiotransferase MiaB [Translation, ribosomal structure and biogenesis]; tRNA A37 methylthiotransferase MiaB is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440386 [Multi-domain]  Cd Length: 435  Bit Score: 43.53  E-value: 8.15e-06
                         10        20        30
                 ....*....|....*....|....*....|..
gi 819231783  64 KIWIRTWGCSHNNSDGEYMAGQLAAYGYKITA 95
Cdd:COG0621    3 KVYIVTLGCQMNQVDSERMAGLLEAAGYELVD 34
PRK14328 PRK14328
(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional
 63-94 5.55e-03

(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional


Pssm-ID: 237675 [Multi-domain]  Cd Length: 439  Bit Score: 35.73  E-value: 5.55e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 819231783  63 QKIWIRTWGCSHNNSDGEYMAGQLAAYGYKIT 94
Cdd:PRK14328   2 KKYFIETYGCQMNEEDSEKLAGMLKSMGYERT 33
 
Name Accession Description Interval E-value
UPF0004 pfam00919
Uncharacterized protein family UPF0004; This family is the N terminal half of the Prosite ...
 64-94 1.19e-07

Uncharacterized protein family UPF0004; This family is the N terminal half of the Prosite family. The C-terminal half has been shown to be related to MiaB proteins. This domain is a nearly always found in conjunction with pfam04055 and pfam01938 although its function is uncertain.


Pssm-ID: 459997 [Multi-domain]  Cd Length: 98  Bit Score: 46.35  E-value: 1.19e-07
                          10        20        30
                  ....*....|....*....|....*....|.
gi 819231783   64 KIWIRTWGCSHNNSDGEYMAGQLAAYGYKIT 94
Cdd:pfam00919   1 KVYIETLGCQMNQADSEIMAGLLEKAGYEVV 31
MiaB COG0621
tRNA A37 methylthiotransferase MiaB [Translation, ribosomal structure and biogenesis]; tRNA ...
 64-95 8.15e-06

tRNA A37 methylthiotransferase MiaB [Translation, ribosomal structure and biogenesis]; tRNA A37 methylthiotransferase MiaB is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440386 [Multi-domain]  Cd Length: 435  Bit Score: 43.53  E-value: 8.15e-06
                         10        20        30
                 ....*....|....*....|....*....|..
gi 819231783  64 KIWIRTWGCSHNNSDGEYMAGQLAAYGYKITA 95
Cdd:COG0621    3 KVYIVTLGCQMNQVDSERMAGLLEAAGYELVD 34
PRK14328 PRK14328
(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional
 63-94 5.55e-03

(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional


Pssm-ID: 237675 [Multi-domain]  Cd Length: 439  Bit Score: 35.73  E-value: 5.55e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 819231783  63 QKIWIRTWGCSHNNSDGEYMAGQLAAYGYKIT 94
Cdd:PRK14328   2 KKYFIETYGCQMNEEDSEKLAGMLKSMGYERT 33
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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