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Conserved domains on  [gi|295789151|ref|NP_001171458|]
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zinc finger MYM-type protein 3 isoform 4 [Mus musculus]

Protein Classification

TRASH and zf-FCS domain-containing protein( domain architecture ID 10654501)

TRASH and zf-FCS domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 393-434 5.21e-08

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 48.91  E-value: 5.21e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 295789151  393 LGRKTCTFCKKEIWNTKDSVVVQtgPGGSFHEFCTSVCLSLY 434
Cdd:pfam06467   1 LVKATCWFCKKLIKNKPTVIVLQ--NDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 491-533 3.39e-07

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 46.59  E-value: 3.39e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 295789151  491 LKTNCCDQCGAYIYARPGGlgpELLFHDGQQKRFCNTTCLGAY 533
Cdd:pfam06467   1 LVKATCWFCKKLIKNKPTV---IVLQNDGSVGQFCSQSCLDSY 40
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 39-349 2.01e-06

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.94  E-value: 2.01e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295789151   39 GPYPAMDPSDFPSPFDPLTLPEKPLAGD----LPVDMEFGEDLLESQTAPSRGWAPPGPSPSSGALDLLDTPSGLEKDPG 114
Cdd:PHA03307   60 AACDRFEPPTGPPPGPGTEAPANESRSTptwsLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLR 139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295789151  115 GVLDGATELLGLGGLLYKAPSPPEVD--HGPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGAGASPPSPEGllEPLAPDS 192
Cdd:PHA03307  140 PVGSPGPPPAASPPAAGASPAAVASDaaSSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRS--SPISASA 217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295789151  193 PIILESPHIEEEIPPLATRRRGSP--------GQEEEHTQGQPQSPNAP-----PSPSVGETLGDGINSSQSKPGVCTPT 259
Cdd:PHA03307  218 SSPAPAPGRSAADDAGASSSDSSSsessgcgwGPENECPLPRPAPITLPtriweASGWNGPSSRPGPASSSSSPRERSPS 297

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295789151  260 AHPSLPGDGLTgkeieKPPERVQKRSERVRRAEPPKP---EVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMS 336
Cdd:PHA03307  298 PSPSSPGSGPA-----PSSPRASSSSSSSRESSSSSTsssSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPS 372

                         330
                  ....*....|...
gi 295789151  337 LRSSMAQRAGRSS 349
Cdd:PHA03307  373 RAPSSPAASAGRP 385
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 449-485 1.22e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 39.66  E-value: 1.22e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 295789151  449 ADATRCSICQKTGEVLHE---VSNGSVVHRLCSDSCFSKF 485
Cdd:pfam06467   1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
356-392 1.52e-04

metallochaperone-like domain;


:

Pssm-ID: 214799  Cd Length: 39  Bit Score: 39.28  E-value: 1.52e-04
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 295789151   356 CAHCRTPLQKGQTA--YQRKGLPQLFCSSSCLTTYSKKP 392
Cdd:smart00746   1 CSFCGKDIYNPGTGimVVNDGKVYYFCSSKCLSKFKKKR 39
 
Name Accession Description Interval E-value
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 393-434 5.21e-08

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 48.91  E-value: 5.21e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 295789151  393 LGRKTCTFCKKEIWNTKDSVVVQtgPGGSFHEFCTSVCLSLY 434
Cdd:pfam06467   1 LVKATCWFCKKLIKNKPTVIVLQ--NDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 491-533 3.39e-07

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 46.59  E-value: 3.39e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 295789151  491 LKTNCCDQCGAYIYARPGGlgpELLFHDGQQKRFCNTTCLGAY 533
Cdd:pfam06467   1 LVKATCWFCKKLIKNKPTV---IVLQNDGSVGQFCSQSCLDSY 40
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 39-349 2.01e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.94  E-value: 2.01e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295789151   39 GPYPAMDPSDFPSPFDPLTLPEKPLAGD----LPVDMEFGEDLLESQTAPSRGWAPPGPSPSSGALDLLDTPSGLEKDPG 114
Cdd:PHA03307   60 AACDRFEPPTGPPPGPGTEAPANESRSTptwsLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLR 139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295789151  115 GVLDGATELLGLGGLLYKAPSPPEVD--HGPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGAGASPPSPEGllEPLAPDS 192
Cdd:PHA03307  140 PVGSPGPPPAASPPAAGASPAAVASDaaSSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRS--SPISASA 217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295789151  193 PIILESPHIEEEIPPLATRRRGSP--------GQEEEHTQGQPQSPNAP-----PSPSVGETLGDGINSSQSKPGVCTPT 259
Cdd:PHA03307  218 SSPAPAPGRSAADDAGASSSDSSSsessgcgwGPENECPLPRPAPITLPtriweASGWNGPSSRPGPASSSSSPRERSPS 297

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295789151  260 AHPSLPGDGLTgkeieKPPERVQKRSERVRRAEPPKP---EVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMS 336
Cdd:PHA03307  298 PSPSSPGSGPA-----PSSPRASSSSSSSRESSSSSTsssSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPS 372

                         330
                  ....*....|...
gi 295789151  337 LRSSMAQRAGRSS 349
Cdd:PHA03307  373 RAPSSPAASAGRP 385
TRASH smart00746
metallochaperone-like domain;
496-535 3.01e-05

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 41.21  E-value: 3.01e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 295789151   496 CDQCGAYIYaRPGGlgPELLFHDGQQKRFCNTTCLGAYKK 535
Cdd:smart00746   1 CSFCGKDIY-NPGT--GIMVVNDGKVYYFCSSKCLSKFKK 37
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 449-485 1.22e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 39.66  E-value: 1.22e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 295789151  449 ADATRCSICQKTGEVLHE---VSNGSVVHRLCSDSCFSKF 485
Cdd:pfam06467   1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
356-392 1.52e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 39.28  E-value: 1.52e-04
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 295789151   356 CAHCRTPLQKGQTA--YQRKGLPQLFCSSSCLTTYSKKP 392
Cdd:smart00746   1 CSFCGKDIYNPGTGimVVNDGKVYYFCSSKCLSKFKKKR 39
TRASH smart00746
metallochaperone-like domain;
398-438 2.86e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.43  E-value: 2.86e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 295789151   398 CTFCKKEIWNTKDSVVVQTGpGGSFHeFCTSVCLSLYEAQQ 438
Cdd:smart00746   1 CSFCGKDIYNPGTGIMVVND-GKVYY-FCSSKCLSKFKKKR 39
TRASH smart00746
metallochaperone-like domain;
454-489 7.31e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 34.27  E-value: 7.31e-03
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 295789151   454 CSICQKTGEVLHEVS---NGSVVHRLCSDSCFSKFRANK 489
Cdd:smart00746   1 CSFCGKDIYNPGTGImvvNDGKVYYFCSSKCLSKFKKKR 39
 
Name Accession Description Interval E-value
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 393-434 5.21e-08

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 48.91  E-value: 5.21e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 295789151  393 LGRKTCTFCKKEIWNTKDSVVVQtgPGGSFHEFCTSVCLSLY 434
Cdd:pfam06467   1 LVKATCWFCKKLIKNKPTVIVLQ--NDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 491-533 3.39e-07

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 46.59  E-value: 3.39e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 295789151  491 LKTNCCDQCGAYIYARPGGlgpELLFHDGQQKRFCNTTCLGAY 533
Cdd:pfam06467   1 LVKATCWFCKKLIKNKPTV---IVLQNDGSVGQFCSQSCLDSY 40
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 39-349 2.01e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.94  E-value: 2.01e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295789151   39 GPYPAMDPSDFPSPFDPLTLPEKPLAGD----LPVDMEFGEDLLESQTAPSRGWAPPGPSPSSGALDLLDTPSGLEKDPG 114
Cdd:PHA03307   60 AACDRFEPPTGPPPGPGTEAPANESRSTptwsLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLR 139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295789151  115 GVLDGATELLGLGGLLYKAPSPPEVD--HGPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGAGASPPSPEGllEPLAPDS 192
Cdd:PHA03307  140 PVGSPGPPPAASPPAAGASPAAVASDaaSSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRS--SPISASA 217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295789151  193 PIILESPHIEEEIPPLATRRRGSP--------GQEEEHTQGQPQSPNAP-----PSPSVGETLGDGINSSQSKPGVCTPT 259
Cdd:PHA03307  218 SSPAPAPGRSAADDAGASSSDSSSsessgcgwGPENECPLPRPAPITLPtriweASGWNGPSSRPGPASSSSSPRERSPS 297

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295789151  260 AHPSLPGDGLTgkeieKPPERVQKRSERVRRAEPPKP---EVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMS 336
Cdd:PHA03307  298 PSPSSPGSGPA-----PSSPRASSSSSSSRESSSSSTsssSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPS 372

                         330
                  ....*....|...
gi 295789151  337 LRSSMAQRAGRSS 349
Cdd:PHA03307  373 RAPSSPAASAGRP 385
TRASH smart00746
metallochaperone-like domain;
496-535 3.01e-05

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 41.21  E-value: 3.01e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 295789151   496 CDQCGAYIYaRPGGlgPELLFHDGQQKRFCNTTCLGAYKK 535
Cdd:smart00746   1 CSFCGKDIY-NPGT--GIMVVNDGKVYYFCSSKCLSKFKK 37
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 76-349 5.19e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.32  E-value: 5.19e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295789151   76 DLLESQTAPSRGWAPPGPSPSSGALDLLDTPSGLEKDPGGVLD------GATELLGLGGLLYKAPSPPEVDHGPEGTLAW 149
Cdd:PHA03307    9 DLIEAAAEGGEFFPRPPATPGDAADDLLSGSQGQLVSDSAELAavtvvaGAAACDRFEPPTGPPPGPGTEAPANESRSTP 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295789151  150 DSGEQTLEPGPGCQTPEVMPPDPGAGASPPSPEGLLEPLAPDSPIILESPHIEEEIPPLATRRRGSPGQEEEHTQGQPQS 229
Cdd:PHA03307   89 TWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAAS 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295789151  230 PN--APPSPSVGETLGDGINSSQSKPGVCTPTAHPslPGDGLTGKEIEKPPERVQKRSERVRRAEPPKPEVVDSTESIPV 307
Cdd:PHA03307  169 SRqaALPLSSPEETARAPSSPPAEPPPSTPPAAAS--PRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSG 246

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 295789151  308 SDEDSDAMVDDPNDEDFV-PFRPRRSPRMSLRSSMAQRAGRSS 349
Cdd:PHA03307  247 CGWGPENECPLPRPAPITlPTRIWEASGWNGPSSRPGPASSSS 289
PHA03247 PHA03247
large tegument protein UL36; Provisional
 27-320 5.61e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.47  E-value: 5.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295789151   27 GVVTKPEPFNWQGPYPAMDPSDFPSPfDPLTLPEKPLAGDLPVdmefgedlLESQTAPSRGWAPPGP-SPSSGALDLLDT 105
Cdd:PHA03247 2753 GPARPARPPTTAGPPAPAPPAAPAAG-PPRRLTRPAVASLSES--------RESLPSPWDPADPPAAvLAPAAALPPAAS 2823

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295789151  106 PSGLEKDPGGVLDGATEllglggllyKAPSPPEVDHGPEGTLAwdSGEQTLEPGPGCQTPEV-----MPPDPGAGASPPS 180
Cdd:PHA03247 2824 PAGPLPPPTSAQPTAPP---------PPPGPPPPSLPLGGSVA--PGGDVRRRPPSRSPAAKpaapaRPPVRRLARPAVS 2892

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295789151  181 PEGLLEPLAPDSPIILESPHIEEEIPPLATRRRGSPGQEEEHTQGQPQSPNAPPSPSVGetlgdginSSQSKPGVCTPTA 260
Cdd:PHA03247 2893 RSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAG--------AGEPSGAVPQPWL 2964

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 295789151  261 HPSLPGdgltgkEIEKPPERVQKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPN 320
Cdd:PHA03247 2965 GALVPG------RVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLALHEETD 3018
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 449-485 1.22e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 39.66  E-value: 1.22e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 295789151  449 ADATRCSICQKTGEVLHE---VSNGSVVHRLCSDSCFSKF 485
Cdd:pfam06467   1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
356-392 1.52e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 39.28  E-value: 1.52e-04
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 295789151   356 CAHCRTPLQKGQTA--YQRKGLPQLFCSSSCLTTYSKKP 392
Cdd:smart00746   1 CSFCGKDIYNPGTGimVVNDGKVYYFCSSKCLSKFKKKR 39
TRASH smart00746
metallochaperone-like domain;
398-438 2.86e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.43  E-value: 2.86e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 295789151   398 CTFCKKEIWNTKDSVVVQTGpGGSFHeFCTSVCLSLYEAQQ 438
Cdd:smart00746   1 CSFCGKDIYNPGTGIMVVND-GKVYY-FCSSKCLSKFKKKR 39
TRASH smart00746
metallochaperone-like domain;
454-489 7.31e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 34.27  E-value: 7.31e-03
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 295789151   454 CSICQKTGEVLHEVS---NGSVVHRLCSDSCFSKFRANK 489
Cdd:smart00746   1 CSFCGKDIYNPGTGImvvNDGKVYYFCSSKCLSKFKKKR 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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