NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|295444883|ref|NP_001171231|]
View 

tumor necrosis factor alpha-induced protein 8 isoform 3 [Mus musculus]

Protein Classification

TNFAIP8 family protein( domain architecture ID 10527599)

tumor necrosis factor alpha-induced protein 8 (TNFAIP8) family protein is a DUF758 domain-containing protein similar to vertebrate TNFAIP8 that acts as a negative mediator of apoptosis and may play a role in tumor progression

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DUF758 pfam05527
Domain of unknown function (DUF758); Family of eukaryotic proteins with unknown function, ...
 27-109 7.92e-40

Domain of unknown function (DUF758); Family of eukaryotic proteins with unknown function, which are induced by tumour necrosis factor.


:

Pssm-ID: 461672  Cd Length: 160  Bit Score: 130.77  E-value: 7.92e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295444883   27 SIATTLIDDTSSEVLDELYRVTKEYTQNKKEAERVIKNLIKTVIKLAVLHRNNQFNQDELALMEKFKKKVHQLAMTVVSF 106
Cdd:pfam05527   1 SVAKLFIDDTSSELLDNLYRLAKEYTGNKKEAEKVVKNLIKIVVKVGVLYRNNQFSAEELALLEKFRRKFHQLAMTAISF 80


                  ...
gi 295444883  107 HQI 109
Cdd:pfam05527  81 YEV 83
 
Name Accession Description Interval E-value
DUF758 pfam05527
Domain of unknown function (DUF758); Family of eukaryotic proteins with unknown function, ...
 27-109 7.92e-40

Domain of unknown function (DUF758); Family of eukaryotic proteins with unknown function, which are induced by tumour necrosis factor.


Pssm-ID: 461672  Cd Length: 160  Bit Score: 130.77  E-value: 7.92e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295444883   27 SIATTLIDDTSSEVLDELYRVTKEYTQNKKEAERVIKNLIKTVIKLAVLHRNNQFNQDELALMEKFKKKVHQLAMTVVSF 106
Cdd:pfam05527   1 SVAKLFIDDTSSELLDNLYRLAKEYTGNKKEAEKVVKNLIKIVVKVGVLYRNNQFSAEELALLEKFRRKFHQLAMTAISF 80


                  ...
gi 295444883  107 HQI 109
Cdd:pfam05527  81 YEV 83
 
Name Accession Description Interval E-value
DUF758 pfam05527
Domain of unknown function (DUF758); Family of eukaryotic proteins with unknown function, ...
 27-109 7.92e-40

Domain of unknown function (DUF758); Family of eukaryotic proteins with unknown function, which are induced by tumour necrosis factor.


Pssm-ID: 461672  Cd Length: 160  Bit Score: 130.77  E-value: 7.92e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295444883   27 SIATTLIDDTSSEVLDELYRVTKEYTQNKKEAERVIKNLIKTVIKLAVLHRNNQFNQDELALMEKFKKKVHQLAMTVVSF 106
Cdd:pfam05527   1 SVAKLFIDDTSSELLDNLYRLAKEYTGNKKEAEKVVKNLIKIVVKVGVLYRNNQFSAEELALLEKFRRKFHQLAMTAISF 80


                  ...
gi 295444883  107 HQI 109
Cdd:pfam05527  81 YEV 83
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH