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Conserved domains on  [gi|281182834|ref|NP_001162089|]
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intraflagellar transport protein 46 homolog isoform 2 [Homo sapiens]

Protein Classification

intraflagellar transport protein 46( domain architecture ID 10574223)

intraflagellar transport protein 46 (IFT46) forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IFT46_B_C pfam12317
Intraflagellar transport complex B protein 46 C terminal; This family of proteins is found in ...
 65-267 2.16e-147

Intraflagellar transport complex B protein 46 C terminal; This family of proteins is found in eukaryotes. Proteins in this family are typically between 298 and 416 amino acids in length. IFT46 is a flagellar protein of complex B. Like all IFT proteins, it is required for transport of IFT particles into the flagella.


:

Pssm-ID: 463532  Cd Length: 203  Bit Score: 411.97  E-value: 2.16e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281182834   65 DPADYEHLPVSAEIKELFQYISRYTPQLIDLDHKLKPFIPDFIPAVGDIDAFLKVPRPDGKPDNLGLLVLDEPSTKQSDP 144
Cdd:pfam12317   1 DPADYENLPVSAEIKELFQYITRYTPQTIELDTKLKPFIPDYIPAVGDIDAFLKVPRPDGKPDNLGLTVLDEPSANQSDP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281182834  145 TVLSLWLTENSKQHNITQHMKVKSLEDAEKNPKAIDTWIESISELHRSKPPATVHYTRPMPDIDTLMQEWSPEFEELLGK 224
Cdd:pfam12317  81 TVLDLQLRSISKQSAGKPDVVVKSIENAEKNPKAIDKWIESIEELHRSKPPPTVHYSKPMPDIETLMQEWPPEFEEALNK 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 281182834  225 VSLPTAEIDCSLAEYIDMICAILDIPVYKSRIQSLHLLFSLYS 267
Cdd:pfam12317 161 VGLPSAELDCDLAEYVDIICAILDIPVYGSRIESLHLLFTLYL 203
 
Name Accession Description Interval E-value
IFT46_B_C pfam12317
Intraflagellar transport complex B protein 46 C terminal; This family of proteins is found in ...
 65-267 2.16e-147

Intraflagellar transport complex B protein 46 C terminal; This family of proteins is found in eukaryotes. Proteins in this family are typically between 298 and 416 amino acids in length. IFT46 is a flagellar protein of complex B. Like all IFT proteins, it is required for transport of IFT particles into the flagella.


Pssm-ID: 463532  Cd Length: 203  Bit Score: 411.97  E-value: 2.16e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281182834   65 DPADYEHLPVSAEIKELFQYISRYTPQLIDLDHKLKPFIPDFIPAVGDIDAFLKVPRPDGKPDNLGLLVLDEPSTKQSDP 144
Cdd:pfam12317   1 DPADYENLPVSAEIKELFQYITRYTPQTIELDTKLKPFIPDYIPAVGDIDAFLKVPRPDGKPDNLGLTVLDEPSANQSDP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281182834  145 TVLSLWLTENSKQHNITQHMKVKSLEDAEKNPKAIDTWIESISELHRSKPPATVHYTRPMPDIDTLMQEWSPEFEELLGK 224
Cdd:pfam12317  81 TVLDLQLRSISKQSAGKPDVVVKSIENAEKNPKAIDKWIESIEELHRSKPPPTVHYSKPMPDIETLMQEWPPEFEEALNK 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 281182834  225 VSLPTAEIDCSLAEYIDMICAILDIPVYKSRIQSLHLLFSLYS 267
Cdd:pfam12317 161 VGLPSAELDCDLAEYVDIICAILDIPVYGSRIESLHLLFTLYL 203
 
Name Accession Description Interval E-value
IFT46_B_C pfam12317
Intraflagellar transport complex B protein 46 C terminal; This family of proteins is found in ...
 65-267 2.16e-147

Intraflagellar transport complex B protein 46 C terminal; This family of proteins is found in eukaryotes. Proteins in this family are typically between 298 and 416 amino acids in length. IFT46 is a flagellar protein of complex B. Like all IFT proteins, it is required for transport of IFT particles into the flagella.


Pssm-ID: 463532  Cd Length: 203  Bit Score: 411.97  E-value: 2.16e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281182834   65 DPADYEHLPVSAEIKELFQYISRYTPQLIDLDHKLKPFIPDFIPAVGDIDAFLKVPRPDGKPDNLGLLVLDEPSTKQSDP 144
Cdd:pfam12317   1 DPADYENLPVSAEIKELFQYITRYTPQTIELDTKLKPFIPDYIPAVGDIDAFLKVPRPDGKPDNLGLTVLDEPSANQSDP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281182834  145 TVLSLWLTENSKQHNITQHMKVKSLEDAEKNPKAIDTWIESISELHRSKPPATVHYTRPMPDIDTLMQEWSPEFEELLGK 224
Cdd:pfam12317  81 TVLDLQLRSISKQSAGKPDVVVKSIENAEKNPKAIDKWIESIEELHRSKPPPTVHYSKPMPDIETLMQEWPPEFEEALNK 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 281182834  225 VSLPTAEIDCSLAEYIDMICAILDIPVYKSRIQSLHLLFSLYS 267
Cdd:pfam12317 161 VGLPSAELDCDLAEYVDIICAILDIPVYGSRIESLHLLFTLYL 203
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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