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Conserved domains on  [gi|209977087|ref|NP_001129698|]
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U3 small nucleolar RNA-associated protein 14 homolog B [Mus musculus]

Protein Classification

UTP14 family protein( domain architecture ID 12054186)

UTP14 family protein may be required for ribosome biogenesis, similar to human U3 small nucleolar RNA-associated protein 14 homolog C (UTP14C) that is essential for spermatogenesis

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
Utp14 pfam04615
Utp14 protein; This protein is found to be part of a large ribonucleoprotein complex ...
68-743 2.81e-153

Utp14 protein; This protein is found to be part of a large ribonucleoprotein complex containing the U3 snoRNA. Depletion of the Utp proteins impedes production of the 18S rRNA, indicating that they are part of the active pre-rRNA processing complex. This large RNP complex has been termed the small subunit (SSU) processome.


:

Pssm-ID: 461368 [Multi-domain]  Cd Length: 704  Bit Score: 463.73  E-value: 2.81e-153
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087   68 QKLLEAVSSL-GRKNKWKLAERSEASRMVSEFNVTSegsGEKLVLSDLLGSATalSSVAAVKKQLHRV----KSKTLTPP 142
Cdd:pfam04615   1 DKLLSFISGLdGKKKKRKLKDRTEEAGQESEFGLTS---GGKLSLADLLLPLV--KKDSSLKKSLKLLekekKSKKLAAP 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  143 LNKEEADRALREAAFSKTSQMLSRWDPVVLKNRQAEQLIFPMEK-EPPAVAPIEHVFTDWKVRTPLEREVFNLLHKNKqP 221
Cdd:pfam04615  76 LPKRQQDRLDRKAAYEKTKEELDKWEPTVKRNRRAEHLSFPLQQpDTVGKSTLAPLASKFKPRTELEKKIASILEESG-L 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  222 VTDPLLTPVETASIRAMSLEEAKIRRAELQRTRALQSYYEARARREKRIKSKKYHRALKKGKAKKALKEFEELWKDCPNA 301
Cdd:pfam04615 155 AEEKKLATFEELALNKLSVEEVKERRAELRKMRELMFREEAKAKRIKKIKSKTYRRIHRKEREKEAEKEEEALAEAALED 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  302 ALQELEKMEKARMTERMSLKHQGSGKWAKS--KAIMAKYDPEARKAMQEQLAKNRELTQKLQVVSESEEEDgcteEGIVS 379
Cdd:pfam04615 235 DEEEREKQERKRAEERMTLKHKNTSKWAKSmkKRGRAAWDEETRAALAEQLRRGEELRRKIEGKDVSDDDD----DSDDD 310
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  380 VSHGMDDLQMNADGVNPWMLSSCNSNAKRGEIKTDP-------------------EQMPEFVA------HVSSESEGDER 434
Cdd:pfam04615 311 SSDSEDEDDNDAKLVKRKKLGKLKELEEKAEEEEEGpesgllsmkfmkraearrkEENDEEIEelrrelEQGDEEDGDEE 390
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  435 PVAEELVLKERSF-----QERVDPNNAKLMDGQETEDSDSQEVLQKLNKESHQSDNQKVSSEENVLHIQREDLASEKLLV 509
Cdd:pfam04615 391 EEEEQGNVGRRVFgpgakVKSLKSKKKKSDSKVDSSKREEFEEDKSKDLEDRAKKKKAKKSSKESKKLASEAASEEEADD 470
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  510 LQRLERAHVLEQQGELSKEEHYPKKGLSRPLLKGDwKEMKPLTNPDASGGKKKKEQMIDLRNLLTANSSPVRSLAVPTiQ 589
Cdd:pfam04615 471 ESNPWLDESKTAKKTSSKVEVFVDKSSSKATKSKN-KIKKSKKKNSSKKKSSKDDALIDIDLSNTLKDESDDDDDDEE-E 548
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  590 QLEDEVETDHKQLIREAFAGDDVIREFLKEKREAIETNKPKDLDLSLPGWGEWVGMGLKPSAKKRRRFLIKAP--ESSPR 667
Cdd:pfam04615 549 EVDLPVAFKQRDLIARAFAGDDVVAEFEKEKKRVIEEEDPKEIDNTLPGWGSWAGDGVKKREKKKRKFLKKVEgvKKKKR 628
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 209977087  668 KDKNLPNVIISEKRNIHAAAHQVRALPHPFTHQQQFERTIQNPIGYMWNTQRTFQKLTVPKVGTKLGHIIKPIKAE 743
Cdd:pfam04615 629 KDAKLKNVIINEKRDKKNAKYLASQLPFPFESKEQYERSLRMPIGPEWNTKETFQKLTKPRVVTKQGVIIKPLKKP 704
 
Name Accession Description Interval E-value
Utp14 pfam04615
Utp14 protein; This protein is found to be part of a large ribonucleoprotein complex ...
68-743 2.81e-153

Utp14 protein; This protein is found to be part of a large ribonucleoprotein complex containing the U3 snoRNA. Depletion of the Utp proteins impedes production of the 18S rRNA, indicating that they are part of the active pre-rRNA processing complex. This large RNP complex has been termed the small subunit (SSU) processome.


Pssm-ID: 461368 [Multi-domain]  Cd Length: 704  Bit Score: 463.73  E-value: 2.81e-153
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087   68 QKLLEAVSSL-GRKNKWKLAERSEASRMVSEFNVTSegsGEKLVLSDLLGSATalSSVAAVKKQLHRV----KSKTLTPP 142
Cdd:pfam04615   1 DKLLSFISGLdGKKKKRKLKDRTEEAGQESEFGLTS---GGKLSLADLLLPLV--KKDSSLKKSLKLLekekKSKKLAAP 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  143 LNKEEADRALREAAFSKTSQMLSRWDPVVLKNRQAEQLIFPMEK-EPPAVAPIEHVFTDWKVRTPLEREVFNLLHKNKqP 221
Cdd:pfam04615  76 LPKRQQDRLDRKAAYEKTKEELDKWEPTVKRNRRAEHLSFPLQQpDTVGKSTLAPLASKFKPRTELEKKIASILEESG-L 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  222 VTDPLLTPVETASIRAMSLEEAKIRRAELQRTRALQSYYEARARREKRIKSKKYHRALKKGKAKKALKEFEELWKDCPNA 301
Cdd:pfam04615 155 AEEKKLATFEELALNKLSVEEVKERRAELRKMRELMFREEAKAKRIKKIKSKTYRRIHRKEREKEAEKEEEALAEAALED 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  302 ALQELEKMEKARMTERMSLKHQGSGKWAKS--KAIMAKYDPEARKAMQEQLAKNRELTQKLQVVSESEEEDgcteEGIVS 379
Cdd:pfam04615 235 DEEEREKQERKRAEERMTLKHKNTSKWAKSmkKRGRAAWDEETRAALAEQLRRGEELRRKIEGKDVSDDDD----DSDDD 310
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  380 VSHGMDDLQMNADGVNPWMLSSCNSNAKRGEIKTDP-------------------EQMPEFVA------HVSSESEGDER 434
Cdd:pfam04615 311 SSDSEDEDDNDAKLVKRKKLGKLKELEEKAEEEEEGpesgllsmkfmkraearrkEENDEEIEelrrelEQGDEEDGDEE 390
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  435 PVAEELVLKERSF-----QERVDPNNAKLMDGQETEDSDSQEVLQKLNKESHQSDNQKVSSEENVLHIQREDLASEKLLV 509
Cdd:pfam04615 391 EEEEQGNVGRRVFgpgakVKSLKSKKKKSDSKVDSSKREEFEEDKSKDLEDRAKKKKAKKSSKESKKLASEAASEEEADD 470
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  510 LQRLERAHVLEQQGELSKEEHYPKKGLSRPLLKGDwKEMKPLTNPDASGGKKKKEQMIDLRNLLTANSSPVRSLAVPTiQ 589
Cdd:pfam04615 471 ESNPWLDESKTAKKTSSKVEVFVDKSSSKATKSKN-KIKKSKKKNSSKKKSSKDDALIDIDLSNTLKDESDDDDDDEE-E 548
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  590 QLEDEVETDHKQLIREAFAGDDVIREFLKEKREAIETNKPKDLDLSLPGWGEWVGMGLKPSAKKRRRFLIKAP--ESSPR 667
Cdd:pfam04615 549 EVDLPVAFKQRDLIARAFAGDDVVAEFEKEKKRVIEEEDPKEIDNTLPGWGSWAGDGVKKREKKKRKFLKKVEgvKKKKR 628
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 209977087  668 KDKNLPNVIISEKRNIHAAAHQVRALPHPFTHQQQFERTIQNPIGYMWNTQRTFQKLTVPKVGTKLGHIIKPIKAE 743
Cdd:pfam04615 629 KDAKLKNVIINEKRDKKNAKYLASQLPFPFESKEQYERSLRMPIGPEWNTKETFQKLTKPRVVTKQGVIIKPLKKP 704
COG5644 COG5644
U3 small nucleolar RNA-associated protein 14 [Function unknown];
41-744 8.23e-65

U3 small nucleolar RNA-associated protein 14 [Function unknown];


Pssm-ID: 227931 [Multi-domain]  Cd Length: 869  Bit Score: 232.29  E-value: 8.23e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  41 EELVDLPENYPLSTSEDEGDSdgegKRQKLLEAVSSlGRKNKWKLAERSEASrmvsefnvtseGSGEKLVLSDLLGSATA 120
Cdd:COG5644  188 DSKLDNLRNYIVSLKKDEADA----ESVLSSDDNDS-IEEIKYDPHETNKES-----------GSSETIDITDLLDSIPM 251
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087 121 LSSVAAVKkqLHRVKSKTLTPPLNKEEADRALREAAFSKTSQMLSRWDPVVLKNRQAEQLIFPMEKEPPAVAPIEHVFTD 200
Cdd:COG5644  252 EQLKVSLK--PLVSESSKLDAPLAKSIQDRLERQAAYEQTKNDLEKWKPIVADNRKSDQLIFPMNETARPVPSNNGLASS 329
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087 201 WKVRTPLEREVFNLLhKNKQPVTDPLLTPVETASIRAMSLEEAKIRRAELQRTRALQSYYEARARREKRIKSKKYHRALK 280
Cdd:COG5644  330 FEPRTESERKMHQAL-LDAGLENESALKKQEELALNKLSVEEVAERTRQLRFMRELMFREERKAKRVAKIKSKTYRKIRK 408
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087 281 KgkakkalkEFEELWKDCPNAALQELEKMEKARMTERMSLKHQGSGKWAKSKAIMAKYDPEARKAMQEQLAKNRELTQKL 360
Cdd:COG5644  409 N--------RKEKEMALIPKSEDLENEKSEEARALERMTQRHKNTSSWTRKMLERASHGEGTREAVNEQIRKGDELMQRI 480
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087 361 QVVSESEEEDGC--------TEEGIVSVSHGMDDlQMNADGVNPWMLSSCNSNAKRgeiktdpEQMPEFVAHVSSESEGD 432
Cdd:COG5644  481 HGKEIMDGEDVSefsdsdydTNEQVSTAFEKIRN-EEELKGVLGMKFMRDASNRQM-------AASKISVADLVKVENGD 552
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087 433 ERPVAEElvlkersfqervDPNNAKLMDGQETEDSDSQEVLQKLNKESHQSDNQKVSSEENVLHIQREDLASEKllvlQR 512
Cdd:COG5644  553 DIDVGEL------------DEVGGDAIYANAGRREVFPVVEQRRKLAPRKRKEDFVTPSTSLEKSMDRILHGQK----KR 616
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087 513 LERAHVLEQQGELSKEEHYpkkGLSRPL--LKGDWKEMKPLTNPDASGGKKKKEQMIDLRNLLtaNSSPVRSLAVPTIQQ 590
Cdd:COG5644  617 AEGAVVFEKPLEATENFNP---WLDRKMrrIKRIKKKAYRRIRRDKRLKKKMPEEENTQENHL--GSEKKRHGGVPDILL 691
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087 591 LEDEVETDHK----------------------QLIREAFAGDDVIREFLKEKREAIETNKPKDLDLSLPGWGEWVGMGLK 648
Cdd:COG5644  692 KEIEVEDDEKtpilspggdeeveeglsiktqeELVALAFAGDDVVAEFEEEKREIVNREAPKEEDVVLPGWGEWAGPGLK 771
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087 649 PSAKKRR--RFLIKAPESSPRKDKNLPNVIISEKRNIHAAAHQVRALPHPFTHQQQFERTIQNPIGYMWNTQRTFQKLTV 726
Cdd:COG5644  772 VIKKKSNtvKKVVGGIKYSKRKDFNLSHVIINEKVNKKDKKFLADEVPFPFETREQYERSLNAPIGREWTTRASHKRLVR 851
                        730
                 ....*....|....*...
gi 209977087 727 PKVGTKLGHIIKPIKAEN 744
Cdd:COG5644  852 PRTRTKNGEVIEPFKAPP 869
 
Name Accession Description Interval E-value
Utp14 pfam04615
Utp14 protein; This protein is found to be part of a large ribonucleoprotein complex ...
68-743 2.81e-153

Utp14 protein; This protein is found to be part of a large ribonucleoprotein complex containing the U3 snoRNA. Depletion of the Utp proteins impedes production of the 18S rRNA, indicating that they are part of the active pre-rRNA processing complex. This large RNP complex has been termed the small subunit (SSU) processome.


Pssm-ID: 461368 [Multi-domain]  Cd Length: 704  Bit Score: 463.73  E-value: 2.81e-153
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087   68 QKLLEAVSSL-GRKNKWKLAERSEASRMVSEFNVTSegsGEKLVLSDLLGSATalSSVAAVKKQLHRV----KSKTLTPP 142
Cdd:pfam04615   1 DKLLSFISGLdGKKKKRKLKDRTEEAGQESEFGLTS---GGKLSLADLLLPLV--KKDSSLKKSLKLLekekKSKKLAAP 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  143 LNKEEADRALREAAFSKTSQMLSRWDPVVLKNRQAEQLIFPMEK-EPPAVAPIEHVFTDWKVRTPLEREVFNLLHKNKqP 221
Cdd:pfam04615  76 LPKRQQDRLDRKAAYEKTKEELDKWEPTVKRNRRAEHLSFPLQQpDTVGKSTLAPLASKFKPRTELEKKIASILEESG-L 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  222 VTDPLLTPVETASIRAMSLEEAKIRRAELQRTRALQSYYEARARREKRIKSKKYHRALKKGKAKKALKEFEELWKDCPNA 301
Cdd:pfam04615 155 AEEKKLATFEELALNKLSVEEVKERRAELRKMRELMFREEAKAKRIKKIKSKTYRRIHRKEREKEAEKEEEALAEAALED 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  302 ALQELEKMEKARMTERMSLKHQGSGKWAKS--KAIMAKYDPEARKAMQEQLAKNRELTQKLQVVSESEEEDgcteEGIVS 379
Cdd:pfam04615 235 DEEEREKQERKRAEERMTLKHKNTSKWAKSmkKRGRAAWDEETRAALAEQLRRGEELRRKIEGKDVSDDDD----DSDDD 310
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  380 VSHGMDDLQMNADGVNPWMLSSCNSNAKRGEIKTDP-------------------EQMPEFVA------HVSSESEGDER 434
Cdd:pfam04615 311 SSDSEDEDDNDAKLVKRKKLGKLKELEEKAEEEEEGpesgllsmkfmkraearrkEENDEEIEelrrelEQGDEEDGDEE 390
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  435 PVAEELVLKERSF-----QERVDPNNAKLMDGQETEDSDSQEVLQKLNKESHQSDNQKVSSEENVLHIQREDLASEKLLV 509
Cdd:pfam04615 391 EEEEQGNVGRRVFgpgakVKSLKSKKKKSDSKVDSSKREEFEEDKSKDLEDRAKKKKAKKSSKESKKLASEAASEEEADD 470
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  510 LQRLERAHVLEQQGELSKEEHYPKKGLSRPLLKGDwKEMKPLTNPDASGGKKKKEQMIDLRNLLTANSSPVRSLAVPTiQ 589
Cdd:pfam04615 471 ESNPWLDESKTAKKTSSKVEVFVDKSSSKATKSKN-KIKKSKKKNSSKKKSSKDDALIDIDLSNTLKDESDDDDDDEE-E 548
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  590 QLEDEVETDHKQLIREAFAGDDVIREFLKEKREAIETNKPKDLDLSLPGWGEWVGMGLKPSAKKRRRFLIKAP--ESSPR 667
Cdd:pfam04615 549 EVDLPVAFKQRDLIARAFAGDDVVAEFEKEKKRVIEEEDPKEIDNTLPGWGSWAGDGVKKREKKKRKFLKKVEgvKKKKR 628
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 209977087  668 KDKNLPNVIISEKRNIHAAAHQVRALPHPFTHQQQFERTIQNPIGYMWNTQRTFQKLTVPKVGTKLGHIIKPIKAE 743
Cdd:pfam04615 629 KDAKLKNVIINEKRDKKNAKYLASQLPFPFESKEQYERSLRMPIGPEWNTKETFQKLTKPRVVTKQGVIIKPLKKP 704
COG5644 COG5644
U3 small nucleolar RNA-associated protein 14 [Function unknown];
41-744 8.23e-65

U3 small nucleolar RNA-associated protein 14 [Function unknown];


Pssm-ID: 227931 [Multi-domain]  Cd Length: 869  Bit Score: 232.29  E-value: 8.23e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087  41 EELVDLPENYPLSTSEDEGDSdgegKRQKLLEAVSSlGRKNKWKLAERSEASrmvsefnvtseGSGEKLVLSDLLGSATA 120
Cdd:COG5644  188 DSKLDNLRNYIVSLKKDEADA----ESVLSSDDNDS-IEEIKYDPHETNKES-----------GSSETIDITDLLDSIPM 251
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087 121 LSSVAAVKkqLHRVKSKTLTPPLNKEEADRALREAAFSKTSQMLSRWDPVVLKNRQAEQLIFPMEKEPPAVAPIEHVFTD 200
Cdd:COG5644  252 EQLKVSLK--PLVSESSKLDAPLAKSIQDRLERQAAYEQTKNDLEKWKPIVADNRKSDQLIFPMNETARPVPSNNGLASS 329
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087 201 WKVRTPLEREVFNLLhKNKQPVTDPLLTPVETASIRAMSLEEAKIRRAELQRTRALQSYYEARARREKRIKSKKYHRALK 280
Cdd:COG5644  330 FEPRTESERKMHQAL-LDAGLENESALKKQEELALNKLSVEEVAERTRQLRFMRELMFREERKAKRVAKIKSKTYRKIRK 408
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087 281 KgkakkalkEFEELWKDCPNAALQELEKMEKARMTERMSLKHQGSGKWAKSKAIMAKYDPEARKAMQEQLAKNRELTQKL 360
Cdd:COG5644  409 N--------RKEKEMALIPKSEDLENEKSEEARALERMTQRHKNTSSWTRKMLERASHGEGTREAVNEQIRKGDELMQRI 480
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087 361 QVVSESEEEDGC--------TEEGIVSVSHGMDDlQMNADGVNPWMLSSCNSNAKRgeiktdpEQMPEFVAHVSSESEGD 432
Cdd:COG5644  481 HGKEIMDGEDVSefsdsdydTNEQVSTAFEKIRN-EEELKGVLGMKFMRDASNRQM-------AASKISVADLVKVENGD 552
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087 433 ERPVAEElvlkersfqervDPNNAKLMDGQETEDSDSQEVLQKLNKESHQSDNQKVSSEENVLHIQREDLASEKllvlQR 512
Cdd:COG5644  553 DIDVGEL------------DEVGGDAIYANAGRREVFPVVEQRRKLAPRKRKEDFVTPSTSLEKSMDRILHGQK----KR 616
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087 513 LERAHVLEQQGELSKEEHYpkkGLSRPL--LKGDWKEMKPLTNPDASGGKKKKEQMIDLRNLLtaNSSPVRSLAVPTIQQ 590
Cdd:COG5644  617 AEGAVVFEKPLEATENFNP---WLDRKMrrIKRIKKKAYRRIRRDKRLKKKMPEEENTQENHL--GSEKKRHGGVPDILL 691
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087 591 LEDEVETDHK----------------------QLIREAFAGDDVIREFLKEKREAIETNKPKDLDLSLPGWGEWVGMGLK 648
Cdd:COG5644  692 KEIEVEDDEKtpilspggdeeveeglsiktqeELVALAFAGDDVVAEFEEEKREIVNREAPKEEDVVLPGWGEWAGPGLK 771
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977087 649 PSAKKRR--RFLIKAPESSPRKDKNLPNVIISEKRNIHAAAHQVRALPHPFTHQQQFERTIQNPIGYMWNTQRTFQKLTV 726
Cdd:COG5644  772 VIKKKSNtvKKVVGGIKYSKRKDFNLSHVIINEKVNKKDKKFLADEVPFPFETREQYERSLNAPIGREWTTRASHKRLVR 851
                        730
                 ....*....|....*...
gi 209977087 727 PKVGTKLGHIIKPIKAEN 744
Cdd:COG5644  852 PRTRTKNGEVIEPFKAPP 869
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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