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Conserved domains on  [gi|194440687|ref|NP_001123949|]
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serine/arginine repetitive matrix protein 1 isoform 2 [Mus musculus]

Protein Classification

PWI domain-containing protein( domain architecture ID 10478549)

PWI domain-containing protein may function as a splicing factor; similar to Homo sapiens serine/arginine repetitive matrix protein 1 that is involved in numerous pre-mRNA processing events

CATH:  1.20.1390.10
Gene Ontology:  GO:0006397|GO:0003676
PubMed:  10322432|12600940
SCOP:  4000671

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PWI pfam01480
PWI domain;
46-115 3.86e-38

PWI domain;


:

Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 136.48  E-value: 3.86e-38
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687   46 EVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNgKNAREFMGELWPLLLSAQEN 115
Cdd:pfam01480   1 EVLKPWIEKKITEILGFEDDVVVEYVVNLLEEKFPDPKELQIQLTGFLD-KDAAKFVKELWKLLLSAQES 69
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 619-816 5.66e-06

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.55  E-value: 5.66e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  619 SPSPPPKRRTASPPPPPKR---RASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPqpnkr 695
Cdd:PHA03307  101 AREGSPTPPGPSSPDPPPPtppPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALP----- 175

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  696 hSPSPRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAK 775
Cdd:PHA03307  176 -LSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENE 254

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 194440687  776 KPPAPPSPVQSQSPSTNWSPAVPAKKAKSPTPSLSPARNSD 816
Cdd:PHA03307  255 CPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERS 295
 
Name Accession Description Interval E-value
PWI pfam01480
PWI domain;
46-115 3.86e-38

PWI domain;


Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 136.48  E-value: 3.86e-38
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687   46 EVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNgKNAREFMGELWPLLLSAQEN 115
Cdd:pfam01480   1 EVLKPWIEKKITEILGFEDDVVVEYVVNLLEEKFPDPKELQIQLTGFLD-KDAAKFVKELWKLLLSAQES 69
PWI smart00311
PWI, domain in splicing factors;
40-115 1.98e-28

PWI, domain in splicing factors;


Pssm-ID: 214609 [Multi-domain]  Cd Length: 74  Bit Score: 108.97  E-value: 1.98e-28
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 194440687    40 MSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEV-KNPDSKMMQINLTGFLngkNAREFMGELWPLLLSAQEN 115
Cdd:smart00311   1 LSKLKLDEIKPWITKKVIEFLGFEEDTLVEFILSQIRQhKGPQAKLLQINLTGFE---DAEEFVDKLWRLLIFELKN 74
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 619-816 5.66e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.55  E-value: 5.66e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  619 SPSPPPKRRTASPPPPPKR---RASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPqpnkr 695
Cdd:PHA03307  101 AREGSPTPPGPSSPDPPPPtppPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALP----- 175

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  696 hSPSPRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAK 775
Cdd:PHA03307  176 -LSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENE 254

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 194440687  776 KPPAPPSPVQSQSPSTNWSPAVPAKKAKSPTPSLSPARNSD 816
Cdd:PHA03307  255 CPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERS 295
Pneumo_att_G pfam05539
Pneumovirinae attachment membrane glycoprotein G;
622-755 3.13e-04

Pneumovirinae attachment membrane glycoprotein G;


Pssm-ID: 114270 [Multi-domain]  Cd Length: 408  Bit Score: 44.27  E-value: 3.13e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  622 PPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNKRHSPSPR 701
Cdd:pfam05539 168 PKTAVTTSKTTSWPTEVSHPTYPSQVTPQSQPATQGHQTATANQRLSSTEPVGTQGTTTSSNPEPQTEPPPSQRGPSGSP 247

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 194440687  702 PRAPQTSSPPPVRRGAS--ASPQGRQSPSPS-TRPIRRVSRTPEPKKIKKAASPSPQ 755
Cdd:pfam05539 248 QHPPSTTSQDQSTTGDGqeHTQRRKTPPATSnRRSPHSTATPPPTTKRQETGRPTPR 304
 
Name Accession Description Interval E-value
PWI pfam01480
PWI domain;
46-115 3.86e-38

PWI domain;


Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 136.48  E-value: 3.86e-38
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687   46 EVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNgKNAREFMGELWPLLLSAQEN 115
Cdd:pfam01480   1 EVLKPWIEKKITEILGFEDDVVVEYVVNLLEEKFPDPKELQIQLTGFLD-KDAAKFVKELWKLLLSAQES 69
PWI smart00311
PWI, domain in splicing factors;
40-115 1.98e-28

PWI, domain in splicing factors;


Pssm-ID: 214609 [Multi-domain]  Cd Length: 74  Bit Score: 108.97  E-value: 1.98e-28
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 194440687    40 MSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEV-KNPDSKMMQINLTGFLngkNAREFMGELWPLLLSAQEN 115
Cdd:smart00311   1 LSKLKLDEIKPWITKKVIEFLGFEEDTLVEFILSQIRQhKGPQAKLLQINLTGFE---DAEEFVDKLWRLLIFELKN 74
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 619-816 5.66e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.55  E-value: 5.66e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  619 SPSPPPKRRTASPPPPPKR---RASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPqpnkr 695
Cdd:PHA03307  101 AREGSPTPPGPSSPDPPPPtppPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALP----- 175

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  696 hSPSPRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAK 775
Cdd:PHA03307  176 -LSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENE 254

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 194440687  776 KPPAPPSPVQSQSPSTNWSPAVPAKKAKSPTPSLSPARNSD 816
Cdd:PHA03307  255 CPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERS 295
PHA03247 PHA03247
large tegument protein UL36; Provisional
 619-814 8.18e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.94  E-value: 8.18e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  619 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVShSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRST-REARSPQPNKRHS 697
Cdd:PHA03247 2753 GPARPARPPTTAGPPAPAPPAAPAAGPPRRLT-RPAVASLSESRESLPSPWDPADPPAAVLAPAAAlPPAASPAGPLPPP 2831

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  698 PSPRPRAPQTSSPP---------------PVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSS 762
Cdd:PHA03247 2832 TSAQPTAPPPPPGPpppslplggsvapggDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQP 2911

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 194440687  763 SRSVSGSPEPAAKKPPAPPSPVQSQS-PSTNWSPAVPAKKAKSPTPSLSPARN 814
Cdd:PHA03247 2912 QAPPPPQPQPQPPPPPQPQPPPPPPPrPQPPLAPTTDPAGAGEPSGAVPQPWL 2964
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 617-812 5.92e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 46.90  E-value: 5.92e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687 617 RYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNKRH 696
Cdd:PRK07764 585 EAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASD 664

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687 697 SPSPRPR----APQTSSPPPVRRGASASPQGRQSPSPSTRPirRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEP 772
Cdd:PRK07764 665 GGDGWPAkaggAAPAAPPPAPAPAAPAAPAGAAPAQPAPAP--AATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLP 742

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 194440687 773 AAKKPPAPPSPVQSQSPSTNWSPAVPAKKAKSPTPSLSPA 812
Cdd:PRK07764 743 PEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEE 782
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
620-815 5.95e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 46.79  E-value: 5.95e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687 620 PSPPPKRRTASPPPPPKRRASPSPPPKrrVSHSPPPKQRSPTvtkRRSPSLSS--KHRKGSSPGRSTREARSPQPNKRHS 697
Cdd:PRK12323 385 PAPAAAAPAAAAPAPAAPPAAPAAAPA--AAAAARAVAAAPA---RRSPAPEAlaAARQASARGPGGAPAPAPAPAAAPA 459

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687 698 PSPRPRAPQTSSPPPvrrgASASPQGRQSPSPSTRPIRRvSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKP 777
Cdd:PRK12323 460 AAARPAAAGPRPVAA----AAAAAPARAAPAAAPAPADD-DPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPATADP 534

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 194440687 778 PAPPSpvqSQSPSTNWSPAVPAKKAKSPTPSLSPARNS 815
Cdd:PRK12323 535 DDAFE---TLAPAPAAAPAPRAAAATEPVVAPRPPRAS 569
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 373-722 6.18e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 47.09  E-value: 6.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  373 SPPRKTRRLSPSASPPRRRHRPSSPATPPPktrhSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRK 452
Cdd:PHA03307   99 SPAREGSPTPPGPSSPDPPPPTPPPASPPP----SPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAAL 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  453 VELSESEEDKGSKMAAADSVQQRRQYRRQNQQSSSDSGSSSTSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKE 532
Cdd:PHA03307  175 PLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENE 254

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  533 TsPRmqmgkrwQSPVTKSSRRRRSPSPPPARRRRSPSPAPPPPPPPPPPRRRRSPTPPPRRRTPSPPPRRRSPSPRRYSP 612
Cdd:PHA03307  255 C-PL-------PRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSS 326

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  613 PIQRRYSPSPppkrRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSskhrKGSSPGRSTREARSPQP 692
Cdd:PHA03307  327 SSTSSSSESS----RGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAAS----AGRPTRRRARAAVAGRA 398

                         330       340       350
                  ....*....|....*....|....*....|
gi 194440687  693 NKRHSPSPRPRAPQTSSPPPVRRGASASPQ 722
Cdd:PHA03307  399 RRRDATGRFPAGRPRPSPLDAGAASGAFYA 428
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 623-820 6.50e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 47.09  E-value: 6.50e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  623 PPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQP---------- 692
Cdd:PHA03307  108 PPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSspeetaraps 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  693 ---------NKRHSPSPRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSS 763
Cdd:PHA03307  188 sppaepppsTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPT 267

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 194440687  764 RSVSGSPEPAAKKPPAPPSPVQS-QSPSTNWSPAVPAKKAKSPTPSLSPARNSDQEGG 820
Cdd:PHA03307  268 RIWEASGWNGPSSRPGPASSSSSpRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESS 325
Pneumo_att_G pfam05539
Pneumovirinae attachment membrane glycoprotein G;
622-755 3.13e-04

Pneumovirinae attachment membrane glycoprotein G;


Pssm-ID: 114270 [Multi-domain]  Cd Length: 408  Bit Score: 44.27  E-value: 3.13e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  622 PPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNKRHSPSPR 701
Cdd:pfam05539 168 PKTAVTTSKTTSWPTEVSHPTYPSQVTPQSQPATQGHQTATANQRLSSTEPVGTQGTTTSSNPEPQTEPPPSQRGPSGSP 247

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 194440687  702 PRAPQTSSPPPVRRGAS--ASPQGRQSPSPS-TRPIRRVSRTPEPKKIKKAASPSPQ 755
Cdd:pfam05539 248 QHPPSTTSQDQSTTGDGqeHTQRRKTPPATSnRRSPHSTATPPPTTKRQETGRPTPR 304
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 617-743 4.70e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 43.93  E-value: 4.70e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687 617 RYSPSPPPKRRTASPPPPPKRRASPSPPPKR---RVSHSPPPKQRSPTVTkrrSPSlsskhrkGSSPGRSTREARSPQPN 693
Cdd:PRK14951 367 AAAAEAAAPAEKKTPARPEAAAPAAAPVAQAaaaPAPAAAPAAAASAPAA---PPA-------AAPPAPVAAPAAAAPAA 436

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 194440687 694 KRHsPSPRPRAPQTSSPPPVRRGASASPQgRQSPSPSTRPIRRVSRTPEP 743
Cdd:PRK14951 437 APA-AAPAAVALAPAPPAQAAPETVAIPV-RVAPEPAVASAAPAPAAAPA 484
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 620-732 9.39e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 42.78  E-value: 9.39e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687 620 PSPPPKRRTASPPPPPKRRASPSPPPKRRVshsPPPKQRSPTVTKrrspslsskhrkgSSPGRSTREARSPQPNKRHSPS 699
Cdd:PRK14951 393 PVAQAAAAPAPAAAPAAAASAPAAPPAAAP---PAPVAAPAAAAP-------------AAAPAAAPAAVALAPAPPAQAA 456

                         90       100       110
                 ....*....|....*....|....*....|....
gi 194440687 700 PRPRA-PQTSSPPPVRRGASASPQGRQSPSPSTR 732
Cdd:PRK14951 457 PETVAiPVRVAPEPAVASAAPAPAAAPAAARLTP 490
KAR9 pfam08580
Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal ...
 619-754 2.60e-03

Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal protein required for karyogamy, correct positioning of the mitotic spindle and for orientation of cytoplasmic microtubules. KAR9 localizes at the shmoo tip in mating cells and at the tip of the growing bud in anaphase.


Pssm-ID: 430088 [Multi-domain]  Cd Length: 684  Bit Score: 41.35  E-value: 2.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  619 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTvtKRRSPSLSSKHRKGSSpgRSTREARSPQPNKRHSP 698
Cdd:pfam08580 483 STLKQTKRPSKIPRASPNHSGFLSTPSNTATSETPTPALRPPS--RPQPPPPGNRPRWNAS--TNTNDLDVGHNFKPLTL 558

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 194440687  699 SPRPRAPQTSSPP--------PVRRGASASPqgrqspSPSTRPIRRVSRTPEPKKIKKAASPSP 754
Cdd:pfam08580 559 TTPSPTPSRSSRSsstlppvsPLSRDKSRSP------APTCRSVSRASRRRASRKPTRIGSPNS 616
PHA03247 PHA03247
large tegument protein UL36; Provisional
 576-810 2.99e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.46  E-value: 2.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  576 PPPPPPRRRRSPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYS-------PSPPPK--RRTASPPP---------PPKR 637
Cdd:PHA03247 2625 DPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARrlgraaqASSPPQrpRRRAARPTvgsltsladPPPP 2704

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  638 RASPSPPPKRRVSHSPPP------KQRSPTVTKRRSPSLSSKhrKGSSPGRSTREARSPQPNKRHSPSPrPRAPQTSSPP 711
Cdd:PHA03247 2705 PPTPEPAPHALVSATPLPpgpaaaRQASPALPAAPAPPAVPA--GPATPGGPARPARPPTTAGPPAPAP-PAAPAAGPPR 2781

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  712 --PVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQ---- 785
Cdd:PHA03247 2782 rlTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVApggd 2861

                         250       260
                  ....*....|....*....|....*.
gi 194440687  786 -SQSPSTNWSPAVPAKKAKSPTPSLS 810
Cdd:PHA03247 2862 vRRRPPSRSPAAKPAAPARPPVRRLA 2887
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 575-811 4.03e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.92  E-value: 4.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  575 PPPPPPPRRRRSPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPP 654
Cdd:PHA03307  128 PSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPP 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  655 PKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNKRHSP---SPRPRAPQTSSPPPVRRGASASPQG-RQSPSPS 730
Cdd:PHA03307  208 RRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPeneCPLPRPAPITLPTRIWEASGWNGPSsRPGPASS 287

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  731 TRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPV-------QSQSPSTNWSPAVPAKKAK 803
Cdd:PHA03307  288 SSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVspgpspsRSPSPSRPPPPADPSSPRK 367


                  ....*...
gi 194440687  804 SPTPSLSP 811
Cdd:PHA03307  368 RPRPSRAP 375
PHA03247 PHA03247
large tegument protein UL36; Provisional
 610-812 5.35e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.69  E-value: 5.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  610 YSPPIQRRYSPSPPPKRRT--------------ASPPPPPKRRASPSPPPKRRVSHS-PPPKQRSPTVTKR-RSPSLSSK 673
Cdd:PHA03247 2515 LAPAILPDEPVGEPVHPRMltwirgleelasddAGDPPPPLPPAAPPAAPDRSVPPPrPAPRPSEPAVTSRaRRPDAPPQ 2594

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  674 HRKGSSPGRSTREARSPQPnkrhsPSPRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIR--------RVSRTPEPKK 745
Cdd:PHA03247 2595 SARPRAPVDDRGDPRGPAP-----PSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERprddpapgRVSRPRRARR 2669

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 194440687  746 IKKAASPS-PQSVRRVSSSRSVSGSPEPAAKKPPAPPSPvqsQSPSTNWSPAVP------AKKAKSPTPSLSPA 812
Cdd:PHA03247 2670 LGRAAQASsPPQRPRRRAARPTVGSLTSLADPPPPPPTP---EPAPHALVSATPlppgpaAARQASPALPAAPA 2740
PHA03247 PHA03247
large tegument protein UL36; Provisional
 617-754 5.73e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.69  E-value: 5.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  617 RYSPSPPPKRRTASPPP----------------PPKRRASPSPPPK----------------RRVSHSPPPKQRSPT-VT 663
Cdd:PHA03247  273 RGATGPPPPPEAAAPNGaaappdgvwgaalagaPLALPAPPDPPPPapagdaeeeddedgamEVVSPLPRPRQHYPLgFP 352

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  664 KRRSPS---------LSS--KHRKGSSPG----RSTREARSP---QPNKRHSPSPRPRAPQTSSPPPVRRGASASPQGRQ 725
Cdd:PHA03247  353 KRRRPTwtppssledLSAgrHHPKRASLPtrkrRSARHAATPfarGPGGDDQTRPAAPVPASVPTPAPTPVPASAPPPPA 432

                         170       180
                  ....*....|....*....|....*....
gi 194440687  726 SPSPSTRPIRRVSRTPEPKKIKKAASPSP 754
Cdd:PHA03247  433 TPLPSAEPGSDDGPAPPPERQPPAPATEP 461
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 620-754 8.20e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 39.85  E-value: 8.20e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687 620 PSPPPKRRTASPPPPPKRRASPSPPPkrrvshSPPPKQRSPTVTKRRSPSLSSKHrkgsspgrSTREARSPQPNKRHSPS 699
Cdd:PRK07994 379 ASAQATAAPTAAVAPPQAPAVPPPPA------SAPQQAPAVPLPETTSQLLAARQ--------QLQRAQGATKAKKSEPA 444

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 194440687 700 PRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKAASPSP 754
Cdd:PRK07994 445 AASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKA 499
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 677-901 9.28e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 39.97  E-value: 9.28e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687 677 GSSPGRSTREARSPQPNKRHSPSPRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIrrvsrTPEPKKIKKAASPSPQS 756
Cdd:PRK07764 590 PAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGV-----AAPEHHPKHVAVPDASD 664

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687 757 VRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPAKKAKSPTPSLSPARNSDQEGGGKKKKKKKDKKHKKDK 836
Cdd:PRK07764 665 GGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPE 744

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 194440687 837 KHKKHKKHKKEKAVTIATPATAAPAAVSAATTTSAQEEPA----AAPEPRKETESEAEDDNLDDLERHL 901
Cdd:PRK07764 745 PDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEmaedDAPSMDDEDRRDAEEVAMELLEEEL 813
Gag_spuma pfam03276
Spumavirus gag protein;
620-728 9.42e-03

Spumavirus gag protein;


Pssm-ID: 460872 [Multi-domain]  Cd Length: 614  Bit Score: 39.73  E-value: 9.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440687  620 PSPPPKRRTASPPPPPK-------RRASPSPPPKRRVS-HSPPPKQRSPTvtkrRSPSLSSKHRKGSSPGRSTREARSPQ 691
Cdd:pfam03276 207 PAIPGIHARAPPGNIARslgddimPSLGDAGMPQPRFAfHPGNPFAEAEG----HPFAEAEGERPRDIPRAPRIDAPSAP 282

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 194440687  692 PNKRHSPSPRPRAPQTSSPPPVRRGASASPQGRQSPS 728
Cdd:pfam03276 283 AIPAIQPIAPPMIPPIGAPIPIPHGASIPGEHIRNPR 319
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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