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Conserved domains on  [gi|147907040|ref|NP_001091491|]
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renin receptor precursor [Bos taurus]

Protein Classification

Renin_r domain-containing protein( domain architecture ID 10545182)

Renin_r domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Renin_r pfam07850
Renin receptor-like protein; The sequences featured in this family are similar to a region of ...
 255-351 1.96e-55

Renin receptor-like protein; The sequences featured in this family are similar to a region of the human renin receptor that bears a putative transmembrane spanning segment. The renin receptor is involved in intracellular signal transduction by the activation of the ERK1/ERK2 pathway, and it also serves to increase the efficiency of angiotensinogen cleavage by receptor-bound renin, therefore facilitating angiotensin II generation and action on a cell surface.


:

Pssm-ID: 462287  Cd Length: 97  Bit Score: 176.34  E-value: 1.96e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147907040  255 LYGGNAVVELVTVRSFDTSLVRKTRNILETKQVKDPSTTYNLAYKYNFEYPVVFNLVLWIMIGLALTLIVTCYNIWNMDP 334
Cdd:pfam07850   1 LYGGNAVVELVTVKAFDGILKRKKRSILQAKQANDPKTPYNLAYKYSSDYPVIFNIILWLMVALVLALIVISYGLWNMDP 80

                          90
                  ....*....|....*..
gi 147907040  335 GYDSIIYRMTNQKIRMD 351
Cdd:pfam07850  81 GRDSIIYRMTTTRMKKD 97
 
Name Accession Description Interval E-value
Renin_r pfam07850
Renin receptor-like protein; The sequences featured in this family are similar to a region of ...
 255-351 1.96e-55

Renin receptor-like protein; The sequences featured in this family are similar to a region of the human renin receptor that bears a putative transmembrane spanning segment. The renin receptor is involved in intracellular signal transduction by the activation of the ERK1/ERK2 pathway, and it also serves to increase the efficiency of angiotensinogen cleavage by receptor-bound renin, therefore facilitating angiotensin II generation and action on a cell surface.


Pssm-ID: 462287  Cd Length: 97  Bit Score: 176.34  E-value: 1.96e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147907040  255 LYGGNAVVELVTVRSFDTSLVRKTRNILETKQVKDPSTTYNLAYKYNFEYPVVFNLVLWIMIGLALTLIVTCYNIWNMDP 334
Cdd:pfam07850   1 LYGGNAVVELVTVKAFDGILKRKKRSILQAKQANDPKTPYNLAYKYSSDYPVIFNIILWLMVALVLALIVISYGLWNMDP 80

                          90
                  ....*....|....*..
gi 147907040  335 GYDSIIYRMTNQKIRMD 351
Cdd:pfam07850  81 GRDSIIYRMTTTRMKKD 97
 
Name Accession Description Interval E-value
Renin_r pfam07850
Renin receptor-like protein; The sequences featured in this family are similar to a region of ...
 255-351 1.96e-55

Renin receptor-like protein; The sequences featured in this family are similar to a region of the human renin receptor that bears a putative transmembrane spanning segment. The renin receptor is involved in intracellular signal transduction by the activation of the ERK1/ERK2 pathway, and it also serves to increase the efficiency of angiotensinogen cleavage by receptor-bound renin, therefore facilitating angiotensin II generation and action on a cell surface.


Pssm-ID: 462287  Cd Length: 97  Bit Score: 176.34  E-value: 1.96e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 147907040  255 LYGGNAVVELVTVRSFDTSLVRKTRNILETKQVKDPSTTYNLAYKYNFEYPVVFNLVLWIMIGLALTLIVTCYNIWNMDP 334
Cdd:pfam07850   1 LYGGNAVVELVTVKAFDGILKRKKRSILQAKQANDPKTPYNLAYKYSSDYPVIFNIILWLMVALVLALIVISYGLWNMDP 80

                          90
                  ....*....|....*..
gi 147907040  335 GYDSIIYRMTNQKIRMD 351
Cdd:pfam07850  81 GRDSIIYRMTTTRMKKD 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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