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Conserved domains on  [gi|2451557013|ref|XP_053825113|]
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GTP:AMP phosphotransferase AK3, mitochondrial isoform X1 [Vidua chalybeata]

Protein Classification

nucleoside monophosphate kinase( domain architecture ID 11995178)

nucleoside monophosphate kinase catalyzes the transfer of the terminal phosphoryl group from a nucleoside triphosphate, usually ATP, to a nucleoside monophosphate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ADK pfam00406
Adenylate kinase;
11-188 5.30e-98

Adenylate kinase;


:

Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 283.05  E-value: 5.30e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  11 IMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLD-QYNWLLD 89
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDcKNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  90 GFPRTVAQAEALDK----ECHIDTVINLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVQGIDDITGEQLVQRDDDKP 165
Cdd:pfam00406  81 GFPRTVPQAEALEEllerGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDNE 160

                         170       180
                  ....*....|....*....|...
gi 2451557013 166 ETVSKRLQAYDAQTKPVLEYYRT 188
Cdd:pfam00406 161 ETVKKRLETYHKQTKPLIDYYKK 183
 
Name Accession Description Interval E-value
ADK pfam00406
Adenylate kinase;
11-188 5.30e-98

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 283.05  E-value: 5.30e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  11 IMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLD-QYNWLLD 89
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDcKNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  90 GFPRTVAQAEALDK----ECHIDTVINLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVQGIDDITGEQLVQRDDDKP 165
Cdd:pfam00406  81 GFPRTVPQAEALEEllerGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDNE 160

                         170       180
                  ....*....|....*....|...
gi 2451557013 166 ETVSKRLQAYDAQTKPVLEYYRT 188
Cdd:pfam00406 161 ETVKKRLETYHKQTKPLIDYYKK 183
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 8-187 6.30e-93

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 271.23  E-value: 6.30e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013   8 RAVIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLD-QYNW 86
Cdd:COG0563     2 RIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDcANGF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  87 LLDGFPRTVAQAEALDK-----ECHIDTVINLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVQGIDDITGEQLVQRD 161
Cdd:COG0563    82 ILDGFPRTVAQAEALDEllaelGIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQRA 161

                         170       180
                  ....*....|....*....|....*.
gi 2451557013 162 DDKPETVSKRLQAYDAQTKPVLEYYR 187
Cdd:COG0563   162 DDNEETVRKRLEVYHEQTAPLIDYYR 187
adk PRK00279
adenylate kinase; Reviewed
 7-187 1.19e-89

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 263.16  E-value: 1.19e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013   7 LRAVIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLD-QYN 85
Cdd:PRK00279    1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDcKNG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  86 WLLDGFPRTVAQAEALDKECH-----IDTVINLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVQGIDDITGEQLVQR 160
Cdd:PRK00279   81 FLLDGFPRTIPQAEALDEMLKelgikLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQR 160

                         170       180
                  ....*....|....*....|....*..
gi 2451557013 161 DDDKPETVSKRLQAYDAQTKPVLEYYR 187
Cdd:PRK00279  161 ADDNEETVRKRLEVYHKQTAPLIDYYK 187
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 8-188 3.39e-88

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 259.47  E-value: 3.39e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013   8 RAVIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLD--QYN 85
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQNDdnENG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  86 WLLDGFPRTVAQAEALDK--ECHIDTVINLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVQGIDDITGEQLVQRDDD 163
Cdd:TIGR01351  81 FILDGFPRTLSQAEALDAllEEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQREDD 160

                         170       180
                  ....*....|....*....|....*
gi 2451557013 164 KPETVSKRLQAYDAQTKPVLEYYRT 188
Cdd:TIGR01351 161 TEEVVKKRLEVYKEQTEPLIDYYKK 185
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 8-187 3.49e-83

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 245.99  E-value: 3.49e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013   8 RAVIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLDQYN-W 86
Cdd:cd01428     1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKPDCKKgF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  87 LLDGFPRTVAQAEALDKECH----IDTVINLDVPFETIKCRLTARWIHPASGRVYNLefsppkvqGIDDITGEQLVQRDD 162
Cdd:cd01428    81 ILDGFPRTVDQAEALDELLDegikPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRSD 152

                         170       180
                  ....*....|....*....|....*
gi 2451557013 163 DKPETVSKRLQAYDAQTKPVLEYYR 187
Cdd:cd01428   153 DNEETIKKRLEVYKEQTAPLIDYYK 177
 
Name Accession Description Interval E-value
ADK pfam00406
Adenylate kinase;
11-188 5.30e-98

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 283.05  E-value: 5.30e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  11 IMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLD-QYNWLLD 89
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDcKNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  90 GFPRTVAQAEALDK----ECHIDTVINLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVQGIDDITGEQLVQRDDDKP 165
Cdd:pfam00406  81 GFPRTVPQAEALEEllerGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDNE 160

                         170       180
                  ....*....|....*....|...
gi 2451557013 166 ETVSKRLQAYDAQTKPVLEYYRT 188
Cdd:pfam00406 161 ETVKKRLETYHKQTKPLIDYYKK 183
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 8-187 6.30e-93

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 271.23  E-value: 6.30e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013   8 RAVIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLD-QYNW 86
Cdd:COG0563     2 RIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDcANGF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  87 LLDGFPRTVAQAEALDK-----ECHIDTVINLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVQGIDDITGEQLVQRD 161
Cdd:COG0563    82 ILDGFPRTVAQAEALDEllaelGIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQRA 161

                         170       180
                  ....*....|....*....|....*.
gi 2451557013 162 DDKPETVSKRLQAYDAQTKPVLEYYR 187
Cdd:COG0563   162 DDNEETVRKRLEVYHEQTAPLIDYYR 187
adk PRK00279
adenylate kinase; Reviewed
 7-187 1.19e-89

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 263.16  E-value: 1.19e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013   7 LRAVIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLD-QYN 85
Cdd:PRK00279    1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDcKNG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  86 WLLDGFPRTVAQAEALDKECH-----IDTVINLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVQGIDDITGEQLVQR 160
Cdd:PRK00279   81 FLLDGFPRTIPQAEALDEMLKelgikLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQR 160

                         170       180
                  ....*....|....*....|....*..
gi 2451557013 161 DDDKPETVSKRLQAYDAQTKPVLEYYR 187
Cdd:PRK00279  161 ADDNEETVRKRLEVYHKQTAPLIDYYK 187
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 8-188 3.39e-88

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 259.47  E-value: 3.39e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013   8 RAVIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLD--QYN 85
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQNDdnENG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  86 WLLDGFPRTVAQAEALDK--ECHIDTVINLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVQGIDDITGEQLVQRDDD 163
Cdd:TIGR01351  81 FILDGFPRTLSQAEALDAllEEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQREDD 160

                         170       180
                  ....*....|....*....|....*
gi 2451557013 164 KPETVSKRLQAYDAQTKPVLEYYRT 188
Cdd:TIGR01351 161 TEEVVKKRLEVYKEQTEPLIDYYKK 185
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 8-187 3.49e-83

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 245.99  E-value: 3.49e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013   8 RAVIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLDQYN-W 86
Cdd:cd01428     1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKPDCKKgF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  87 LLDGFPRTVAQAEALDKECH----IDTVINLDVPFETIKCRLTARWIHPASGRVYNLefsppkvqGIDDITGEQLVQRDD 162
Cdd:cd01428    81 ILDGFPRTVDQAEALDELLDegikPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRSD 152

                         170       180
                  ....*....|....*....|....*
gi 2451557013 163 DKPETVSKRLQAYDAQTKPVLEYYR 187
Cdd:cd01428   153 DNEETIKKRLEVYKEQTAPLIDYYK 177
PLN02674 PLN02674
adenylate kinase
 5-186 3.46e-59

adenylate kinase


Pssm-ID: 178279 [Multi-domain]  Cd Length: 244  Bit Score: 187.01  E-value: 3.46e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013   5 PLLRAVIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLD-Q 83
Cdd:PLN02674   30 PDKRLILIGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGIKAKEAMDKGELVSDDLVVGIIDEAMKKPScQ 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  84 YNWLLDGFPRTVAQAEALD-----KECHIDTVINLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVQGIDDITGEQLV 158
Cdd:PLN02674  110 KGFILDGFPRTVVQAQKLDemlakQGAKIDKVLNFAIDDAILEERITGRWIHPSSGRTYHTKFAPPKVPGVDDVTGEPLI 189

                         170       180
                  ....*....|....*....|....*...
gi 2451557013 159 QRDDDKPETVSKRLQAYDAQTKPVLEYY 186
Cdd:PLN02674  190 QRKDDTAAVLKSRLEAFHKQTEPVIDYY 217
PRK14530 PRK14530
adenylate kinase; Provisional
 8-187 1.03e-50

adenylate kinase; Provisional


Pssm-ID: 237747 [Multi-domain]  Cd Length: 215  Bit Score: 164.19  E-value: 1.03e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013   8 RAVIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKK-----TEVGIlAKSYIDQGQLIPDHIMTQLMLNEIKGLD 82
Cdd:PRK14530    5 RILLLGAPGAGKGTQSSNLAEEFGVEHVTTGDALRANKQMDisdmdTEYDT-PGEYMDAGELVPDAVVNEIVEEALSDAD 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  83 QYnwLLDGFPRTVAQAEALDKECHIDTVINLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVQGIDDITGEQLVQRDD 162
Cdd:PRK14530   84 GF--VLDGYPRNLEQAEYLESITDLDVVLYLDVSEEELVDRLTGRRVCPDCGANYHVEFNQPEEEGVCDECGGELIQRDD 161

                         170       180
                  ....*....|....*....|....*
gi 2451557013 163 DKPETVSKRLQAYDAQTKPVLEYYR 187
Cdd:PRK14530  162 DTEETVRERLDVFEENTEPVIEHYR 186
adk PRK02496
adenylate kinase; Provisional
 8-187 6.90e-44

adenylate kinase; Provisional


Pssm-ID: 179433 [Multi-domain]  Cd Length: 184  Bit Score: 145.66  E-value: 6.90e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013   8 RAVIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLDQYN-W 86
Cdd:PRK02496    3 RLIFLGPPGAGKGTQAVVLAEHLHIPHISTGDILRQAIKEQTPLGIKAQGYMDKGELVPDQLVLDLVQERLQQPDAANgW 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  87 LLDGFPRTVAQAEALDK---ECH--IDTVINLDVPFETIKCRLTARwihpasgrvynlefsppkvqgidditgeqlvQRD 161
Cdd:PRK02496   83 ILDGFPRKVTQAAFLDEllqEIGqsGERVVNLDVPDDVVVERLLAR-------------------------------GRK 131

                         170       180
                  ....*....|....*....|....*.
gi 2451557013 162 DDKPETVSKRLQAYDAQTKPVLEYYR 187
Cdd:PRK02496  132 DDTEEVIRRRLEVYREQTAPLIDYYR 157
PRK14526 PRK14526
adenylate kinase; Provisional
 7-186 8.38e-43

adenylate kinase; Provisional


Pssm-ID: 172992 [Multi-domain]  Cd Length: 211  Bit Score: 143.84  E-value: 8.38e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013   7 LRAVIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLDQY-N 85
Cdd:PRK14526    1 MKLVFLGPPGSGKGTIAKILSNELNYYHISTGDLFRENILNSTPLGKEIKQIVENGQLVPDSITIKIVEDKINTIKNNdN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  86 WLLDGFPRTVAQAEALDKECHIDTVINLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVQGIDDITGEQLVQRDDDKP 165
Cdd:PRK14526   81 FILDGFPRNINQAKALDKFLPNIKIINFLIDEELLIKRLSGRRICKSCNNIFNIYTLPTKEKGICDVCKGDLYQRKDDKE 160

                         170       180
                  ....*....|....*....|.
gi 2451557013 166 ETVSKRLQAYDAQTKPVLEYY 186
Cdd:PRK14526  161 ESLKTRLQEYKLQTKPLIEFY 181
PLN02842 PLN02842
nucleotide kinase
 10-192 1.39e-39

nucleotide kinase


Pssm-ID: 178435 [Multi-domain]  Cd Length: 505  Bit Score: 142.31  E-value: 1.39e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  10 VIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLD--QYNWL 87
Cdd:PLN02842    1 MISGAPASGKGTQCELIVHKFGLVHISTGDLLRAEVSAGTDIGKRAKEFMNSGRLVPDEIVIAMVTGRLSREDakEKGWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  88 LDGFPRTVAQAEALDK-ECHIDTVINLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKvqgiDDITGEQLVQRDDDKPE 166
Cdd:PLN02842   81 LDGYPRSFAQAQSLEKlKIRPDIFILLDVPDEILIDRCVGRRLDPVTGKIYHIKNFPPE----SEEIKARLITRPDDTEE 156

                         170       180
                  ....*....|....*....|....*.
gi 2451557013 167 TVSKRLQAYDAQTKPVLEYYRTVEQK 192
Cdd:PLN02842  157 KVKARLQIYKKNAEAILSTYSDIMVK 182
PRK14527 PRK14527
adenylate kinase; Provisional
 8-188 1.22e-37

adenylate kinase; Provisional


Pssm-ID: 237745 [Multi-domain]  Cd Length: 191  Bit Score: 129.91  E-value: 1.22e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013   8 RAVI-MGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLDQYNW 86
Cdd:PRK14527    7 KVVIfLGPPGAGKGTQAERLAQELGLKKLSTGDILRDHVARGTELGQRAKPIMEAGDLVPDELILALIRDELAGMEPVRV 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  87 LLDGFPRTVAQAEALDK-----ECHIDTVINLDVPFETIKCRLTARwihpasgrvynlefsppkvqgidditGEQlVQRD 161
Cdd:PRK14527   87 IFDGFPRTLAQAEALDRlleelGARLLAVVLLEVPDEELIRRIVER--------------------------ARQ-EGRS 139

                         170       180
                  ....*....|....*....|....*..
gi 2451557013 162 DDKPETVSKRLQAYDAQTKPVLEYYRT 188
Cdd:PRK14527  140 DDNEETVRRRQQVYREQTQPLVDYYEA 166
PRK14528 PRK14528
adenylate kinase; Provisional
 8-187 3.04e-36

adenylate kinase; Provisional


Pssm-ID: 172994 [Multi-domain]  Cd Length: 186  Bit Score: 126.28  E-value: 3.04e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013   8 RAVIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLDQYN-W 86
Cdd:PRK14528    3 NIIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEAKRYMDAGDLVPDSVVIGIIKDRIREADCKNgF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  87 LLDGFPRTVAQAEALD---KECH--IDTVINLDVPFETIKCRLTARWIhpasgrvynlefsppkVQGidditgeqlvqRD 161
Cdd:PRK14528   83 LLDGFPRTVEQADALDallKNEGksIDKAINLEVPDGELLKRLLGRAE----------------IEG-----------RA 135

                         170       180
                  ....*....|....*....|....*.
gi 2451557013 162 DDKPETVSKRLQAYDAQTKPVLEYYR 187
Cdd:PRK14528  136 DDNEATIKNRLDNYNKKTLPLLDFYA 161
PRK13808 PRK13808
adenylate kinase; Provisional
 7-186 1.32e-35

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 128.47  E-value: 1.32e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013   7 LRAVIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLDQYN- 85
Cdd:PRK13808    1 MRLILLGPPGAGKGTQAQRLVQQYGIVQLSTGDMLRAAVAAGTPVGLKAKDIMASGGLVPDEVVVGIISDRIEQPDAANg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  86 WLLDGFPRTVAQAEALD-----KECHIDTVINLDVPFETIKCRLTARwihPASGRVynlefsppkvqgiddiTGEQLvqR 160
Cdd:PRK13808   81 FILDGFPRTVPQAEALDallkdKQLKLDAVVELRVNEGALLARVETR---VAEMRA----------------RGEEV--R 139

                         170       180
                  ....*....|....*....|....*.
gi 2451557013 161 DDDKPETVSKRLQAYDAQTKPVLEYY 186
Cdd:PRK13808  140 ADDTPEVLAKRLASYRAQTEPLVHYY 165
UMP_CMP_kin_fam TIGR01359
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ...
 11-187 3.01e-35

UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.


Pssm-ID: 273576 [Multi-domain]  Cd Length: 185  Bit Score: 123.64  E-value: 3.01e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  11 IMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKK-TEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLDQ-YNWLL 88
Cdd:TIGR01359   4 VLGGPGSGKGTQCAKIVENFGFTHLSAGDLLRAEIKREgSENGSLIESYIKEGKIVPSEVTVELLKKAIQEDGSsKKFLI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  89 DGFPRTVAQAEA----LDKECHIDTVINLDVPFETIKCRLTARwiHPASGRVynlefsppkvqgidditgeqlvqrdDDK 164
Cdd:TIGR01359  84 DGFPRNEENLEAweklMDNKVNFKFVLFFDCPEETMIKRLLKR--GQTSGRV-------------------------DDN 136

                         170       180
                  ....*....|....*....|...
gi 2451557013 165 PETVSKRLQAYDAQTKPVLEYYR 187
Cdd:TIGR01359 137 IETLKKRFRTYNEETLPIIEHFE 159
PLN02459 PLN02459
probable adenylate kinase
 10-188 1.80e-34

probable adenylate kinase


Pssm-ID: 215253 [Multi-domain]  Cd Length: 261  Bit Score: 123.80  E-value: 1.80e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  10 VIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLM---LNEIKGLDQYNW 86
Cdd:PLN02459   33 VFLGCPGVGKGTYASRLSKLLGVPHIATGDLVREEIKSSGPLGAQLKEIVNQGKLVPDEIIFSLLskrLEAGEEEGESGF 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  87 LLDGFPRTVAQAEALDKECHIDTVINLDVPFETIKCRLTARWIHPASGRVYNLE----FSPPKVQGI-------DDITGE 155
Cdd:PLN02459  113 ILDGFPRTVRQAEILEGVTDIDLVVNLKLREEVLVEKCLGRRICSECGKNFNVAdidlKGEDGRPGIvmppllpPPECAS 192

                         170       180       190
                  ....*....|....*....|....*....|...
gi 2451557013 156 QLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRT 188
Cdd:PLN02459  193 KLITRADDTEEVVKARLRVYKEESQPVEDFYRK 225
PRK14531 PRK14531
adenylate kinase; Provisional
 8-187 3.77e-34

adenylate kinase; Provisional


Pssm-ID: 172997 [Multi-domain]  Cd Length: 183  Bit Score: 120.69  E-value: 3.77e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013   8 RAVIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLDQYNWL 87
Cdd:PRK14531    4 RLLFLGPPGAGKGTQAARLCAAHGLRHLSTGDLLRSEVAAGSALGQEAEAVMNRGELVSDALVLAIVESQLKALNSGGWL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  88 LDGFPRTVAQAEALDKechidTVINLDVPFETikcrltarwihpasgrVYNLEFSppkvqgiDDITGEQLVQ--RDDDKP 165
Cdd:PRK14531   84 LDGFPRTVAQAEALEP-----LLEELKQPIEA----------------VVLLELD-------DAVLIERLLArgRADDNE 135

                         170       180
                  ....*....|....*....|..
gi 2451557013 166 ETVSKRLQAYDAQTKPVLEYYR 187
Cdd:PRK14531  136 AVIRNRLEVYREKTAPLIDHYR 157
PRK14532 PRK14532
adenylate kinase; Provisional
 10-187 6.70e-33

adenylate kinase; Provisional


Pssm-ID: 184729 [Multi-domain]  Cd Length: 188  Bit Score: 117.62  E-value: 6.70e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  10 VIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLM---LNEIKGLDQYnw 86
Cdd:PRK14532    4 ILFGPPAAGKGTQAKRLVEERGMVQLSTGDMLRAAIASGSELGQRVKGIMDRGELVSDEIVIALIeerLPEAEAAGGA-- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  87 LLDGFPRTVAQAEALDK-----ECHIDTVINLDVPFETIKCRLTARWihpasgrvynlefsppKVQGidditgeqlvqRD 161
Cdd:PRK14532   82 IFDGFPRTVAQAEALDKmlasrGQKIDVVIRLKVDDEALIERIVKRF----------------EEQG-----------RP 134

                         170       180
                  ....*....|....*....|....*.
gi 2451557013 162 DDKPETVSKRLQAYDAQTKPVLEYYR 187
Cdd:PRK14532  135 DDNPEVFVTRLDAYNAQTAPLLPYYA 160
PRK14529 PRK14529
adenylate kinase; Provisional
 10-179 2.08e-31

adenylate kinase; Provisional


Pssm-ID: 237746 [Multi-domain]  Cd Length: 223  Bit Score: 114.82  E-value: 2.08e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  10 VIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLDQYNWLLD 89
Cdd:PRK14529    4 LIFGPNGSGKGTQGALVKKKYDLAHIESGAIFREHIGGGTELGKKAKEYIDRGDLVPDDITIPMILETLKQDGKNGWLLD 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  90 GFPRTVAQAEALDKECH-----IDTVINLDVPFETIKCRLTARWI------HPAsgrvyNLEFSPPKVQG-IDDITGEQL 157
Cdd:PRK14529   84 GFPRNKVQAEKLWEALQkegmkLDYVIEILLPREVAKNRIMGRRLckndnnHPN-----NIFIDAIKPDGdVCRVCGGEL 158

                         170       180
                  ....*....|....*....|....
gi 2451557013 158 VQRDDDKPET-VSKRLQA-YDAQT 179
Cdd:PRK14529  159 STRADDQDEEaINKRHDIyYDTET 182
PTZ00088 PTZ00088
adenylate kinase 1; Provisional
 7-187 7.12e-31

adenylate kinase 1; Provisional


Pssm-ID: 240262 [Multi-domain]  Cd Length: 229  Bit Score: 113.36  E-value: 7.12e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013   7 LRAVIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEI-KGLDQY- 84
Cdd:PTZ00088    7 LKIVLFGAPGVGKGTFAEILSKKENLKHINMGNILREEIKAKTTIGKEIQKVVTSGNLVPDNLVIAIVKDEIaKVTDDCf 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  85 -NWLLDGFPRTVAQAEALDKECHIDTVINLDVPFETIKCRLTARWIHPASGRVYNL------EFSPPKV---QGIDDITG 154
Cdd:PTZ00088   87 kGFILDGFPRNLKQCKELGKITNIDLFVNIYLPRNILIKKLLGRRICNTCNRNFNIahirsdPYDMPPIlppADCEGCKG 166

                         170       180       190
                  ....*....|....*....|....*....|....
gi 2451557013 155 E-QLVQRDDDKPETVSKRLQAYDAQTKPVLEYYR 187
Cdd:PTZ00088  167 NpKLQKRSDDTEEIVAHRLNTYESTNSPIIQFFK 200
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 11-188 8.16e-28

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 104.51  E-value: 8.16e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  11 IMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQlMLNE--IKGLDQYN-WL 87
Cdd:TIGR01360   8 IVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLD-LLKDamVAALGTSKgFL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  88 LDGFPRTVAQAEALDKEC-HIDTVINLDVPFETIKCRLTARwiHPASGRVynlefsppkvqgidditgeqlvqrdDDKPE 166
Cdd:TIGR01360  87 IDGYPREVKQGEEFERRIgPPTLVLYFDCSEDTMVKRLLKR--AETSGRV-------------------------DDNEK 139

                         170       180
                  ....*....|....*....|..
gi 2451557013 167 TVSKRLQAYDAQTKPVLEYYRT 188
Cdd:TIGR01360 140 TIKKRLETYYKATEPVIAYYET 161
AAA_17 pfam13207
AAA domain;
12-140 1.85e-27

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 101.93  E-value: 1.85e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  12 MGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTevGILAKSYIDQGQLIPDHIMTQLMLNEIKGLD-QYNWLLDG 90
Cdd:pfam13207   1 TGVPGSGKTTQLKKLAEKLGFPHISAGDLLREEAKERG--LVEDRDEMRKLPLEPQKELQKLAAERIAEEAgEGGVIVDG 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2451557013  91 FPRTVAQAEALD-------KECHIDTVINLDVPFETIKCRLTARwihPASGRVY-NLE 140
Cdd:pfam13207  79 HPRIKTPAGYLPglpvevlRELKPDAIILLEADPEEILERRLKD---RTRGRDDdSEE 133
PLN02200 PLN02200
adenylate kinase family protein
 11-186 3.03e-23

adenylate kinase family protein


Pssm-ID: 215125 [Multi-domain]  Cd Length: 234  Bit Score: 93.80  E-value: 3.03e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  11 IMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKKTEVGILAKSYIDQGQLIPDHIMTQLMLNEIKGLDQYNWLLDG 90
Cdd:PLN02200   48 VLGGPGSGKGTQCEKIVETFGFKHLSAGDLLRREIASNSEHGAMILNTIKEGKIVPSEVTVKLIQKEMESSDNNKFLIDG 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  91 FPRTVAQAEALDK--ECHIDTVINLDVPFETIKCRLTARwihpASGRVynlefsppkvqgidditgeqlvqrdDDKPETV 168
Cdd:PLN02200  128 FPRTEENRIAFERiiGAEPNVVLFFDCPEEEMVKRVLNR----NQGRV-------------------------DDNIDTI 178

                         170
                  ....*....|....*...
gi 2451557013 169 SKRLQAYDAQTKPVLEYY 186
Cdd:PLN02200  179 KKRLKVFNALNLPVIDYY 196
ADK_lid pfam05191
Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular ...
 127-162 2.18e-16

Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular divergence in the active site lid. In some organizms, particularly the Gram-positive bacteria, residues in the lid domain have been mutated to cysteines and these cysteine residues are responsible for the binding of a zinc ion. The bound zinc ion in the lid domain, is clearly structurally homologous to Zinc-finger domains. However, it is unclear whether the adenylate kinase lid is a novel zinc-finger DNA/RNA binding domain, or that the lid bound zinc serves a purely structural function.


Pssm-ID: 461578 [Multi-domain]  Cd Length: 36  Bit Score: 70.18  E-value: 2.18e-16
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2451557013 127 RWIHPASGRVYNLEFSPPKVQGIDDITGEQLVQRDD 162
Cdd:pfam05191   1 RRVCPKCGRIYHVYFNPPKVEGVCDVCGGELVQRDD 36
PRK04182 PRK04182
cytidylate kinase; Provisional
 7-43 1.28e-07

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 49.80  E-value: 1.28e-07
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2451557013   7 LRAVIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRD 43
Cdd:PRK04182    1 MIITISGPPGSGKTTVARLLAEKLGLKHVSAGEIFRE 37
cyt_kin_arch TIGR02173
cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. ...
 10-48 1.69e-07

cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. Members of this family are found in the archaea and in spirochaetes, and differ considerably from the common bacterial form of cytidylate kinase described by TIGR00017.


Pssm-ID: 274012 [Multi-domain]  Cd Length: 171  Bit Score: 49.34  E-value: 1.69e-07
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2451557013  10 VIMGPPGSGKGTVSARIIKHFGVKHLSSGDLLRDNMQKK 48
Cdd:TIGR02173   4 TISGPPGSGKTTVAKILAEKLSLKLISAGDIFRELAAKM 42
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 11-40 5.80e-07

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 47.48  E-value: 5.80e-07
                          10        20        30
                  ....*....|....*....|....*....|
gi 2451557013  11 IMGPPGSGKGTVSARIIKHFGVKHLSSGDL 40
Cdd:cd02020     4 IDGPAGSGKSTVAKLLAKKLGLPYLDTGGI 33
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 10-130 3.13e-06

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 45.71  E-value: 3.13e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  10 VIMGPPGSGKGTVSARIIKHFGVKHLsSGDLLR--DNMQKKTEvGI-LAKS-YIDQGQLIPDHImtqlmlneikgldqYN 85
Cdd:cd02021     3 VVMGVSGSGKSTVGKALAERLGAPFI-DGDDLHppANIAKMAA-GIpLNDEdRWPWLQALTDAL--------------LA 66

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2451557013  86 WLLDGFPRTVAQAEAL--------DKECHI--DTVINLDVPFETIKCRLTARWIH 130
Cdd:cd02021    67 KLASAGEGVVVACSALkriyrdilRGGAANprVRFVHLDGPREVLAERLAARKGH 121
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
10-127 7.91e-05

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 41.82  E-value: 7.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  10 VIMGPPGSGKGTVSARIIKHFGVKHLSSgDLLRdnmqkKTevgiLAKSYIDQGQLIPDH------IMTQLMLNEIKG--- 80
Cdd:COG0645     3 LVCGLPGSGKSTLARALAERLGAVRLRS-DVVR-----KR----LFGAGLAPLERSPEAtartyaRLLALARELLAAgrs 72

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2451557013  81 --LDQYNWlldgFPRTVAQAEALDKECHID-TVINLDVPFETIKCRLTAR 127
Cdd:COG0645    73 viLDATFL----RRAQREAFRALAEEAGAPfVLIWLDAPEEVLRERLEAR 118
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 10-127 2.39e-03

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 37.29  E-value: 2.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  10 VIM-GPPGSGKGTVSARIIKHFGVKHLSSgDLLRDNMQKKTEVGILAksYIDQGQLIPDHIMTQLMLNEIKG----LDQY 84
Cdd:pfam13671   2 ILLvGLPGSGKSTLARRLLEELGAVRLSS-DDERKRLFGEGRPSISY--YTDATDRTYERLHELARIALRAGrpviLDAT 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2451557013  85 NWLLDGFPRTVAQAEALDKECHIdtvINLDVPFETIKCRLTAR 127
Cdd:pfam13671  79 NLRRDERARLLALAREYGVPVRI---VVFEAPEEVLRERLAAR 118
PRK11860 PRK11860
bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase;
11-42 2.48e-03

bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase;


Pssm-ID: 237003 [Multi-domain]  Cd Length: 661  Bit Score: 38.49  E-value: 2.48e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2451557013  11 IMGPPGSGKGTVSARIIKHFGVKHLSSGDLLR 42
Cdd:PRK11860  447 IDGPTASGKGTVAARVAEALGYHYLDSGALYR 478
AAA_18 pfam13238
AAA domain;
10-127 7.52e-03

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 35.48  E-value: 7.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451557013  10 VIMGPPGSGKGTVSARIIKHFGVkHLSSGDLLRDNMQKKTEVGILAKSY-IDQGQLipDHIMTQLMlnEIKGLDQY-NWL 87
Cdd:pfam13238   2 LITGTPGVGKTTLAKELSKRLGF-GDNVRDLALENGLVLGDDPETRESKrLDEDKL--DRLLDLLE--ENAALEEGgNLI 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 2451557013  88 LDGFPrtvAQAEA-LDKECHidtVINLDVPFETIKCRLTAR 127
Cdd:pfam13238  77 IDGHL---AELEPeRAKDLV---GIVLRASPEELLERLEKR 111
Cmk COG0283
Cytidylate kinase [Nucleotide transport and metabolism];
13-38 7.72e-03

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440052 [Multi-domain]  Cd Length: 220  Bit Score: 36.54  E-value: 7.72e-03
                          10        20
                  ....*....|....*....|....*.
gi 2451557013  13 GPPGSGKGTVSARIIKHFGVKHLSSG 38
Cdd:COG0283     7 GPAGSGKSTVAKALAKRLGYHYLDTG 32
DEXXQc_UPF1 cd18039
DEXXQ-box helicase domain of UPF1; UPF1 (also called RNA Helicase And ATPase, Regulator Of ...
 11-34 7.83e-03

DEXXQ-box helicase domain of UPF1; UPF1 (also called RNA Helicase And ATPase, Regulator Of Nonsense Transcripts, or ATP-Dependent Helicase RENT1) is an RNA-dependent helicase and ATPase required for nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. It is recruited to mRNAs upon translation termination and undergoes a cycle of phosphorylation and dephosphorylation; its phosphorylation appears to be a key step in NMD. It is recruited by release factors to stalled ribosomes together with the SMG1C protein kinase complex to form the transient SURF (SMG1-UPF1-eRF1-eRF3) complex. In EJC-dependent NMD, the SURF complex associates with the exon junction complex (EJC) located downstream from the termination codon through UPF2 and allows the formation of an UPF1-UPF2-UPF3 surveillance complex which is believed to activate NMD. Diseases associated with UPF1 include juvenile amyotrophic lateral sclerosis and epidermolysis bullosa, junctional, non-Herlitz type. UPF1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350797 [Multi-domain]  Cd Length: 234  Bit Score: 36.46  E-value: 7.83e-03
                          10        20
                  ....*....|....*....|....
gi 2451557013  11 IMGPPGSGKGTVSARIIKHFgVKH 34
Cdd:cd18039    21 IQGPPGTGKTVTSATIVYHL-VKQ 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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