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Conserved domains on  [gi|2217329876|ref|XP_047301161|]
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inactive dipeptidyl peptidase 10 isoform X4 [Homo sapiens]

Protein Classification

S9 family peptidase( domain architecture ID 13559808)

peptidase S9 family protein, an oligopeptidase which may cleave the prolyl bond of short peptides, similar to Apis mellifera venom dipeptidyl peptidase 4 that removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline

CATH:  3.40.50.1820|2.140.10.30
EC:  3.4.-.-
Gene Ontology:  GO:0008236|GO:0006508
MEROPS:  S9
PubMed:  19508187|12369917|35631755
SCOP:  3000102

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DPPIV_N super family cl37636
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
 1-245 2.14e-82

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


The actual alignment was detected with superfamily member pfam00930:

Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 260.71  E-value: 2.14e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876   1 MINDSLVPTMVIPRFT-GALYPKGKQYPYPKAGQVNPTIKLYVVNLYGPTHTlELMPPDSFKSREYYITMVKWVSNTKTV 79
Cdd:pfam00930 119 RFDESEVPIITLPYYTdEGPGPEVREIKYPKAGAPNPTVELFVYDLASGKTV-EVVPPDDLSDADYYITRVKWVPDGKLL 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876  80 VRWLNRAQNISILTVCETTTGACSKKYEMTSDTWLSQQNEEPVFSRDGSKFFMTVPvKQGgrgeFHHVAMFLIQSKSeqi 159
Cdd:pfam00930 198 VQWLNRDQNRLKVVLCDAETGRTVVILEETSDGWVELHQDPHFIKRDGSGFLWISE-RDG----YNHLYLYDLDGKS--- 269

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 160 tVRHLTSGNWEVIKILAYDETTQKIYFLSTESSPRGRQLYSASTEGLLNRQCISCNFMKEqctYFDASFSPMNQHFLLFC 239
Cdd:pfam00930 270 -PIQLTSGNWEVTSILGVDETRDLVYFTATEDSPTERHLYSVSLDSGGEPTCLTDDSGDH---DYSASFSPNGSYYVLTY 345


                  ....*.
gi 2217329876 240 EGPRVP 245
Cdd:pfam00930 346 SGPDTP 351
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
326-528 1.33e-50

Prolyl oligopeptidase family;


:

Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 172.80  E-value: 1.33e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 326 FHIDWD-SVLIDMDnVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIAS 404
Cdd:pfam00326   1 PSFSWNaQLLADRG-YVVAIANGRGSGGYGEAFHDAGKGDLGQNEFDDFIAAAEYLIEQGYTDPDRLAIWGGSYGGYLTG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 405 MILKSDEKLFKCGSVVAPITDLKLYAS----AFSERYLGMPS--KEESTYQAASVLHNVHGLKEEN-ILIIHGTADTKVH 477
Cdd:pfam00326  80 AALNQRPDLFKAAVAHVPVVDWLAYMSdtslPFTERYMEWGNpwDNEEGYDYLSPYSPADNVKVYPpLLLIHGLLDDRVP 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2217329876 478 FQHSAELIKHLIKAGVNYTMQVYPDEGHNV-SEKSKYHLYSTILKFFSDCLK 528
Cdd:pfam00326 160 PWQSLKLVAALQRKGVPFLLLIFPDEGHGIgKPRNKVEEYARELAFLLEYLG 211
 
Name Accession Description Interval E-value
DPPIV_N pfam00930
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
 1-245 2.14e-82

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 260.71  E-value: 2.14e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876   1 MINDSLVPTMVIPRFT-GALYPKGKQYPYPKAGQVNPTIKLYVVNLYGPTHTlELMPPDSFKSREYYITMVKWVSNTKTV 79
Cdd:pfam00930 119 RFDESEVPIITLPYYTdEGPGPEVREIKYPKAGAPNPTVELFVYDLASGKTV-EVVPPDDLSDADYYITRVKWVPDGKLL 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876  80 VRWLNRAQNISILTVCETTTGACSKKYEMTSDTWLSQQNEEPVFSRDGSKFFMTVPvKQGgrgeFHHVAMFLIQSKSeqi 159
Cdd:pfam00930 198 VQWLNRDQNRLKVVLCDAETGRTVVILEETSDGWVELHQDPHFIKRDGSGFLWISE-RDG----YNHLYLYDLDGKS--- 269

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 160 tVRHLTSGNWEVIKILAYDETTQKIYFLSTESSPRGRQLYSASTEGLLNRQCISCNFMKEqctYFDASFSPMNQHFLLFC 239
Cdd:pfam00930 270 -PIQLTSGNWEVTSILGVDETRDLVYFTATEDSPTERHLYSVSLDSGGEPTCLTDDSGDH---DYSASFSPNGSYYVLTY 345


                  ....*.
gi 2217329876 240 EGPRVP 245
Cdd:pfam00930 346 SGPDTP 351
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
326-528 1.33e-50

Prolyl oligopeptidase family;


Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 172.80  E-value: 1.33e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 326 FHIDWD-SVLIDMDnVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIAS 404
Cdd:pfam00326   1 PSFSWNaQLLADRG-YVVAIANGRGSGGYGEAFHDAGKGDLGQNEFDDFIAAAEYLIEQGYTDPDRLAIWGGSYGGYLTG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 405 MILKSDEKLFKCGSVVAPITDLKLYAS----AFSERYLGMPS--KEESTYQAASVLHNVHGLKEEN-ILIIHGTADTKVH 477
Cdd:pfam00326  80 AALNQRPDLFKAAVAHVPVVDWLAYMSdtslPFTERYMEWGNpwDNEEGYDYLSPYSPADNVKVYPpLLLIHGLLDDRVP 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2217329876 478 FQHSAELIKHLIKAGVNYTMQVYPDEGHNV-SEKSKYHLYSTILKFFSDCLK 528
Cdd:pfam00326 160 PWQSLKLVAALQRKGVPFLLLIFPDEGHGIgKPRNKVEEYARELAFLLEYLG 211
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
341-528 4.43e-42

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 150.55  E-value: 4.43e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 341 IVARFDGRGSGFQGlkilqeihRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIASMILKSDEKLFKCGSVV 420
Cdd:COG1506    53 AVLAPDYRGYGESA--------GDWGGDEVDDVLAAIDYLAARPYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVAL 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 421 APITDLKLYA---SAFSERYLGMPSKEESTYQAASVLHNVHGLKEeNILIIHGTADTKVHFQHSAELIKHLIKAGVNYTM 497
Cdd:COG1506   125 AGVSDLRSYYgttREYTERLMGGPWEDPEAYAARSPLAYADKLKT-PLLLIHGEADDRVPPEQAERLYEALKKAGKPVEL 203

                         170       180       190
                  ....*....|....*....|....*....|.
gi 2217329876 498 QVYPDEGHNVSEKSKYHLYSTILKFFSDCLK 528
Cdd:COG1506   204 LVYPGEGHGFSGAGAPDYLERILDFLDRHLK 234
PLN02442 PLN02442
S-formylglutathione hydrolase
 377-505 1.89e-04

S-formylglutathione hydrolase


Pssm-ID: 178061 [Multi-domain]  Cd Length: 283  Bit Score: 43.61  E-value: 1.89e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 377 VKFLLKL-----PYIDSKRLSIFGKGYGGYIASMI-LKSDEKlFKCGSVVAPI---TDLKLYASAFSErYLGmPSKEE-S 446
Cdd:PLN02442  126 VKELPKLlsdnfDQLDTSRASIFGHSMGGHGALTIyLKNPDK-YKSVSAFAPIanpINCPWGQKAFTN-YLG-SDKADwE 202

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 447 TYQAASVLHNVHGLKEEnILIIHGTADTKVHFQHSAELIKHLIK-AGVNYTMQVYPDEGH 505
Cdd:PLN02442  203 EYDATELVSKFNDVSAT-ILIDQGEADKFLKEQLLPENFEEACKeAGAPVTLRLQPGYDH 261
 
Name Accession Description Interval E-value
DPPIV_N pfam00930
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
 1-245 2.14e-82

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 260.71  E-value: 2.14e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876   1 MINDSLVPTMVIPRFT-GALYPKGKQYPYPKAGQVNPTIKLYVVNLYGPTHTlELMPPDSFKSREYYITMVKWVSNTKTV 79
Cdd:pfam00930 119 RFDESEVPIITLPYYTdEGPGPEVREIKYPKAGAPNPTVELFVYDLASGKTV-EVVPPDDLSDADYYITRVKWVPDGKLL 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876  80 VRWLNRAQNISILTVCETTTGACSKKYEMTSDTWLSQQNEEPVFSRDGSKFFMTVPvKQGgrgeFHHVAMFLIQSKSeqi 159
Cdd:pfam00930 198 VQWLNRDQNRLKVVLCDAETGRTVVILEETSDGWVELHQDPHFIKRDGSGFLWISE-RDG----YNHLYLYDLDGKS--- 269

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 160 tVRHLTSGNWEVIKILAYDETTQKIYFLSTESSPRGRQLYSASTEGLLNRQCISCNFMKEqctYFDASFSPMNQHFLLFC 239
Cdd:pfam00930 270 -PIQLTSGNWEVTSILGVDETRDLVYFTATEDSPTERHLYSVSLDSGGEPTCLTDDSGDH---DYSASFSPNGSYYVLTY 345


                  ....*.
gi 2217329876 240 EGPRVP 245
Cdd:pfam00930 346 SGPDTP 351
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
326-528 1.33e-50

Prolyl oligopeptidase family;


Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 172.80  E-value: 1.33e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 326 FHIDWD-SVLIDMDnVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIAS 404
Cdd:pfam00326   1 PSFSWNaQLLADRG-YVVAIANGRGSGGYGEAFHDAGKGDLGQNEFDDFIAAAEYLIEQGYTDPDRLAIWGGSYGGYLTG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 405 MILKSDEKLFKCGSVVAPITDLKLYAS----AFSERYLGMPS--KEESTYQAASVLHNVHGLKEEN-ILIIHGTADTKVH 477
Cdd:pfam00326  80 AALNQRPDLFKAAVAHVPVVDWLAYMSdtslPFTERYMEWGNpwDNEEGYDYLSPYSPADNVKVYPpLLLIHGLLDDRVP 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2217329876 478 FQHSAELIKHLIKAGVNYTMQVYPDEGHNV-SEKSKYHLYSTILKFFSDCLK 528
Cdd:pfam00326 160 PWQSLKLVAALQRKGVPFLLLIFPDEGHGIgKPRNKVEEYARELAFLLEYLG 211
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
341-528 4.43e-42

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 150.55  E-value: 4.43e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 341 IVARFDGRGSGFQGlkilqeihRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIASMILKSDEKLFKCGSVV 420
Cdd:COG1506    53 AVLAPDYRGYGESA--------GDWGGDEVDDVLAAIDYLAARPYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVAL 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 421 APITDLKLYA---SAFSERYLGMPSKEESTYQAASVLHNVHGLKEeNILIIHGTADTKVHFQHSAELIKHLIKAGVNYTM 497
Cdd:COG1506   125 AGVSDLRSYYgttREYTERLMGGPWEDPEAYAARSPLAYADKLKT-PLLLIHGEADDRVPPEQAERLYEALKKAGKPVEL 203

                         170       180       190
                  ....*....|....*....|....*....|.
gi 2217329876 498 QVYPDEGHNVSEKSKYHLYSTILKFFSDCLK 528
Cdd:COG1506   204 LVYPGEGHGFSGAGAPDYLERILDFLDRHLK 234
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 341-527 5.67e-09

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 56.85  E-value: 5.67e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 341 IVARFDGRGSGF-QGLkilqeiHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIASMILKSDEKlFKCGSV 419
Cdd:COG1073    66 NVLAFDYRGYGEsEGE------PREEGSPERRDARAAVDYLRTLPGVDPERIGLLGISLGGGYALNAAATDPR-VKAVIL 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 420 VAPITDLK-----LYASAFSERYLGMPSKEESTY-----QAASVLHNVHGLKeENILIIHGTADTKVHFQHSAELIKhli 489
Cdd:COG1073   139 DSPFTSLEdlaaqRAKEARGAYLPGVPYLPNVRLasllnDEFDPLAKIEKIS-RPLLFIHGEKDEAVPFYMSEDLYE--- 214

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 2217329876 490 KAGVNYTMQVYPDEGHNVSEKSKYHLY-STILKFFSDCL 527
Cdd:COG1073   215 AAAEPKELLIVPGAGHVDLYDRPEEEYfDKLAEFFKKNL 253
COG4099 COG4099
Predicted peptidase [General function prediction only];
376-507 3.63e-07

Predicted peptidase [General function prediction only];


Pssm-ID: 443275 [Multi-domain]  Cd Length: 235  Bit Score: 51.51  E-value: 3.63e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 376 AVKFLLKLPYIDSKRLSIFGKGYGGYIA-SMILKSDEkLFKCGSVVAPITDLklyasAFSERYLGMPskeestyqaasvl 454
Cdd:COG4099   112 LLDDLIAEYRIDPDRIYLTGLSMGGYGTwDLAARYPD-LFAAAVPICGGGDP-----ANAANLKKVP------------- 172

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2217329876 455 hnvhglkeenILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNV 507
Cdd:COG4099   173 ----------VWIFHGAKDDVVPVEESRAMVEALKAAGADVKYTEYPGVGHNS 215
YpfH COG0400
Predicted esterase [General function prediction only];
386-509 3.44e-05

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 44.90  E-value: 3.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 386 IDSKRLSIFGKGYGGYIASMILKSDEKLFKCgsVVApitdlklyasaFSerylGMPSKEESTYQAASVLHNVHglkeenI 465
Cdd:COG0400    86 IDPERIVLAGFSQGAAMALSLALRRPELLAG--VVA-----------LS----GYLPGEEALPAPEAALAGTP------V 142

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2217329876 466 LIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDeGHNVSE 509
Cdd:COG0400   143 FLAHGTQDPVIPVERAREAAEALEAAGADVTYREYPG-GHEISP 185
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
370-505 1.70e-04

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 43.03  E-value: 1.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 370 VKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIAsMILKSDEKLFKCgsVVApitdlklyasafserYLGMPSKEESTYQ 449
Cdd:COG0412    90 AADLRAALDWLKAQPEVDAGRVGVVGFCFGGGLA-LLAAARGPDLAA--AVS---------------FYGGLPADDLLDL 151

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2217329876 450 AASVLHNVhglkeeniLIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGH 505
Cdd:COG0412   152 AARIKAPV--------LLLYGEKDPLVPPEQVAALEAALAAAGVDVELHVYPGAGH 199
PLN02442 PLN02442
S-formylglutathione hydrolase
 377-505 1.89e-04

S-formylglutathione hydrolase


Pssm-ID: 178061 [Multi-domain]  Cd Length: 283  Bit Score: 43.61  E-value: 1.89e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 377 VKFLLKL-----PYIDSKRLSIFGKGYGGYIASMI-LKSDEKlFKCGSVVAPI---TDLKLYASAFSErYLGmPSKEE-S 446
Cdd:PLN02442  126 VKELPKLlsdnfDQLDTSRASIFGHSMGGHGALTIyLKNPDK-YKSVSAFAPIanpINCPWGQKAFTN-YLG-SDKADwE 202

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 447 TYQAASVLHNVHGLKEEnILIIHGTADTKVHFQHSAELIKHLIK-AGVNYTMQVYPDEGH 505
Cdd:PLN02442  203 EYDATELVSKFNDVSAT-ILIDQGEADKFLKEQLLPENFEEACKeAGAPVTLRLQPGYDH 261
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
342-525 1.48e-03

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 40.37  E-value: 1.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 342 VARFDGRGSGfqglkilqEIHRRLGSVE-----VKDQITAVKFLLKLPyidSKRLSIFGKGYGGYIASMILKSDEKLFKc 416
Cdd:COG2267    58 VLAFDLRGHG--------RSDGPRGHVDsfddyVDDLRAALDALRARP---GLPVVLLGHSMGGLIALLYAARYPDRVA- 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329876 417 gSVVapitdlkLYASAFSERYLGMPSkeESTYQAASVLHNVHGLKEEnILIIHGTADTKVHFQHSAELIKHLIKAGvnyT 496
Cdd:COG2267   126 -GLV-------LLAPAYRADPLLGPS--ARWLRALRLAEALARIDVP-VLVLHGGADRVVPPEAARRLAARLSPDV---E 191

                         170       180       190
                  ....*....|....*....|....*....|
gi 2217329876 497 MQVYPDEGHNV-SEKSKYHLYSTILKFFSD 525
Cdd:COG2267   192 LVLLPGARHELlNEPAREEVLAAILAWLER 221
PRK11460 PRK11460
putative hydrolase; Provisional
 432-505 6.16e-03

putative hydrolase; Provisional


Pssm-ID: 183144 [Multi-domain]  Cd Length: 232  Bit Score: 38.48  E-value: 6.16e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2217329876 432 AFSERYLGMPSKEestyQAASVLHnvhglkeenilIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGH 505
Cdd:PRK11460  133 AFSGRYASLPETA----PTATTIH-----------LIHGGEDPVIDVAHAVAAQEALISLGGDVTLDIVEDLGH 191
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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